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PTVTWSRLNEDRRAAVVAAAEAEFAAHGFSQGSLNVIARRAGVAKGSLFQYFADKRDLYAHITDVGSQRV RCYMEDQIRVLDPTRPFFAFLTDLLDVWVAYFAEHPRERSLHAAASFEVDTDTRVSVRAVIHRHYLEVLR PLVRDARGRGDLRPDADTDALLSLLLMILPHLALAPYVRGMDPVLGLDELSPDQPALVVRRYVAVLAAAF APQPLTTATPGGAQSHG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3467 | - | - | 100% (228) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1492 | - | 4e-10 | 32.08% (212) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4194 | - | 1e-07 | 40.98% (61) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0237 | - | 4e-96 | 78.18% (220) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3060 | - | 1e-106 | 85.33% (225) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0232 | - | 4e-96 | 78.18% (220) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 2e-06 | 31.00% (100) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4946 | - | 1e-08 | 28.66% (164) | putative transcriptional regulator, TetR |
| M. marinum M | MMAR_0489 | - | 2e-94 | 78.87% (213) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4938 | - | 8e-97 | 77.38% (221) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3807 | - | 5e-11 | 29.85% (201) | TetR-type regulator |
| M. thermoresistible (build 8) | TH_4573 | - | 2e-06 | 24.53% (159) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_1152 | - | 2e-94 | 78.40% (213) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3467|M.vanbaalenii_PYR-1 --------------------------MPTVTWSRLNEDR-----RAAVVA
Mflv_3060|M.gilvum_PYR-GCK --------------------------MPTVTWSRLGADR-----RAAVVA
Mb0237|M.bovis_AF2122/97 --------------------------MPTVTWARVDPAR-----RAAVVE
Rv0232|M.tuberculosis_H37Rv --------------------------MPTVTWARVDPAR-----RAAVVE
MMAR_0489|M.marinum_M --------------------------MPTVTWARVDPAR-----RAAIVE
MUL_1152|M.ulcerans_Agy99 --------------------------MPTVTWARVDPAR-----RAAIVE
MAV_4938|M.avium_104 --------------------------MPTVTWARVDPAR-----RAAIIE
MSMEG_3807|M.smegmatis_MC2_155 -------------------------MTSSVKPARADATRN----REALLA
MAB_4946|M.abscessus_ATCC_1997 ---------------------MEDPAEPPIRMADRQRARRSELVKEEVVE
TH_4573|M.thermoresistible__bu -------------------------MATQRATADVEEQHESDR-RDQILE
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKR----RGQLLI
. : : ::
Mvan_3467|M.vanbaalenii_PYR-1 AAEAEFAAHGFSQGSLNVIARRAGVAKGSLFQYFADKRDLYAHITDVGSQ
Mflv_3060|M.gilvum_PYR-GCK AAETEFAAHGFSGGSLNVIARRAGVAKGSLFQYFADKRDLYAHITEVGSQ
Mb0237|M.bovis_AF2122/97 AAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLYAFIADIASQ
Rv0232|M.tuberculosis_H37Rv AAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLYAFIADIASQ
MMAR_0489|M.marinum_M AAEAEFGAHGFSQGSLNVIARRARVAKGSLFQYFADKRDLYAYIADIASQ
MUL_1152|M.ulcerans_Agy99 AAEAEFGAHGFSQGSLNVIARRARVAKGSLFQYFADKRDLYAYIADIANQ
MAV_4938|M.avium_104 AAESEFGAHGFSRGSLNVIARKAGVAKGSLFQYFADKRDLYAFIADIGSQ
MSMEG_3807|M.smegmatis_MC2_155 AAEEEFAERGLA-ASVADIARRAGVAKGTVFRHFPTKEDLIAAIVTAHTA
MAB_4946|M.abscessus_ATCC_1997 AALAEFSERGYHQTSIAHIAERLGTGHSMFYRYFTNKRDILEHVVQHATQ
TH_4573|M.thermoresistible__bu AANACFAQLGIHRTSVQDVARAANVSRGTVYRYFEDRTILIEAAIEYGAQ
MLBr_00815|M.leprae_Br4923 VASDVFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMN
.* * * .: :* ..: .:::* : :
Mvan_3467|M.vanbaalenii_PYR-1 RVRCYMEDQIR-VLDPTRPFFAFLTDLLDVWVAYFAEHPRERSLHAAASF
Mflv_3060|M.gilvum_PYR-GCK RVRRHMEDQIR-ILDPGRPFFEFLTDLLDVWVAYFAEHPQDRALHAAASF
Mb0237|M.bovis_AF2122/97 RVRSYMEDLIR-ELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATL
Rv0232|M.tuberculosis_H37Rv RVRSYMEDLIR-ELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATL
MMAR_0489|M.marinum_M RVRTHIEGLIR-ELDSSRPFFEFLTDLLDGWVAYFAEHPRERALHAAATL
MUL_1152|M.ulcerans_Agy99 RVRTHIEGLIR-ELDSSRPFFEFLTDLLDGWVAYFAEHPRERALHAAATL
MAV_4938|M.avium_104 RVRGYIEQLIR-ELDPTRPFFEFLTDLLDGWVAYFADHPHERALHAAATL
MSMEG_3807|M.smegmatis_MC2_155 TLSETARSLVD-APDPGAALLEFLTEAAD--------QRRQHDLTFLQAA
MAB_4946|M.abscessus_ATCC_1997 RTIETLSHTLPGRITSLNEFHDFSVNLGLAYIDLVVADPRLSRLLLQQGA
TH_4573|M.thermoresistible__bu KFYQEIAAAMA----KKSTLAEQLGAMAETHAKILLDHRTRNRLMTDDAE
MLBr_00815|M.leprae_Br4923 NLVSSVQQALR----TTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDN
: . *
Mvan_3467|M.vanbaalenii_PYR-1 EVDTDTRVSVRAVIHRHYLEVLRPLVRDARGRGDLRPDADTDALLSLLLM
Mflv_3060|M.gilvum_PYR-GCK EVDTDARVSVRAVVHRHYLQVLRPLVHAAGTRGDLRPDADTDTMLSLLLM
Mb0237|M.bovis_AF2122/97 EVDTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLL
Rv0232|M.tuberculosis_H37Rv EVDTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLL
MMAR_0489|M.marinum_M EVDTDARISVRSVIHRHYLEVLRPLVRDALARGDLRADSDTDALLSLLLM
MUL_1152|M.ulcerans_Agy99 EVDTDARISVRSVIHRHYLEVLRPLVRDALARGDLRADSDTDALLSLLLM
MAV_4938|M.avium_104 EVDTEARISVQNVIHRHYLEVLRPLVRDARLRGDLRADSDTDALLSLLLL
MSMEG_3807|M.smegmatis_MC2_155 SADDSSVTAARDELHG----YVEQLVAAAREAGAIRADVTGTDVF--LLM
MAB_4946|M.abscessus_ATCC_1997 AVDAEMTAQFCGVFDAG-AAVLGGLLRDGIESGYVREDIDVEAVADSVVG
TH_4573|M.thermoresistible__bu LMR--HMIADADAAVRRTTEFLMPYVQQAKERGEVGSGVDVKAASEWLAR
MLBr_00815|M.leprae_Br4923 ITEPRVAAQVR-VATESCIDAVFALISADSRLDPHRARMVAVGLVGISVD
: : .
Mvan_3467|M.vanbaalenii_PYR-1 ILPHLALAPYVRGMDPVLGLDELSPDQPALVVRRYVAVLAAAFA--PQPL
Mflv_3060|M.gilvum_PYR-GCK ILPHLALAPYVRGMDPVLGLDEIAPEQPALVVRRYVAVLAAAFADTPTPG
Mb0237|M.bovis_AF2122/97 IFPHLALAPYMRGLDPILGLDEPTPEQPALAVRRLVAVLAAAFDAQHPAT
Rv0232|M.tuberculosis_H37Rv IFPHLALAPYMRGLDPILGLDEPTPEQPALAVRRLVAVLAAAFDAQHPAT
MMAR_0489|M.marinum_M IFPHLALAPYMRGLDPILGLDEPTPEQPALAVRRLVAVLTAAYSP----S
MUL_1152|M.ulcerans_Agy99 IFPHLALAPYMRGLDPILGLDEPTPEQPALAVRRLVAVLTAAYSP----S
MAV_4938|M.avium_104 IFPHLALAPYMRGLDPVLGLDEPTPEQPALAVRRLVAVLAAAFSP--APA
MSMEG_3807|M.smegmatis_MC2_155 CTP----------IHVVENLPDPSPD----LWQRYLGILFDGLRP--EGA
MAB_4946|M.abscessus_ATCC_1997 IPLG---------ILARYGHE-PNQDILAARVRATADLVCRGIAP-----
TH_4573|M.thermoresistible__bu IIYS---------FTTVNEGLTFDMSKPATVRRYVERFAVNGLR------
MLBr_00815|M.leprae_Br4923 CAR--------------YWLDTNRPISKSDAVEGTVQFAWGGLSHVPLTR
. . .
Mvan_3467|M.vanbaalenii_PYR-1 TTATPGGAQSHG
Mflv_3060|M.gilvum_PYR-GCK PRQPQPKENSHE
Mb0237|M.bovis_AF2122/97 NSAQTRSEEIT-
Rv0232|M.tuberculosis_H37Rv NSAQTRSEEIT-
MMAR_0489|M.marinum_M LTVEVR--KVT-
MUL_1152|M.ulcerans_Agy99 LTVEVR--KVT-
MAV_4938|M.avium_104 HFATPRSEEVT-
MSMEG_3807|M.smegmatis_MC2_155 HPLPQPPPRLT-
MAB_4946|M.abscessus_ATCC_1997 ------------
TH_4573|M.thermoresistible__bu ------------
MLBr_00815|M.leprae_Br4923 L-----------