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M. avium 104 MAV_5138 (-)

annotation: transcriptional regulator, TetR family protein
coordinates: 5289593 - 5290228
length: 211

PADSSTPNGQTRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILYDIYQQAAERT
LAAVHDDPSMTAREALYQYTVRLLDQIAANPEGAAVYFQEQPYITEWFTKEQVAAVREKETQVYEHVHGL
IDRGIASGEFYECDSHVLALGYIGMTLGAYRWLRPSGRRSAKEIAAEFSTALLRGLIRDEEIRTTSPLGP
*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_5138--100% (211)transcriptional regulator, TetR family protein
M. avium 104MAV_4155-6e-1328.72% (188) TetR-family protein transcriptional regulator
M. avium 104MAV_0110-1e-1033.03% (109) transcriptional regulator, TetR family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0163-1e-10589.52% (210) TetR family transcriptional regulator
M. gilvum PYR-GCKMflv_0719-7e-8777.39% (199) TetR family transcriptional regulator
M. tuberculosis H37RvRv0158-1e-10589.52% (210) TetR family transcriptional regulator
M. leprae Br4923MLBr_00815-1e-1026.50% (200) putative TetR-family transcriptional regulator
M. abscessus ATCC 19977MAB_4574c-1e-7868.27% (208) TetR family transcriptional regulator
M. marinum MMMAR_0381-2e-9783.81% (210) TetR family transcriptional regulator
M. smegmatis MC2 155MSMEG_0120-1e-8674.76% (206) transcriptional regulatory protein
M. thermoresistible (build 8)TH_0160-1e-8878.89% (199) PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY
M. ulcerans Agy99MUL_4731-1e-9783.81% (210) TetR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_0126-8e-9279.51% (205) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0719|M.gilvum_PYR-GCK          -------------------------------------MSRREELLAVATK
Mvan_0126|M.vanbaalenii_PYR-1       ---------------------------MSESTT--NGMSRREELLAVATK
MSMEG_0120|M.smegmatis_MC2_155      ---------------------------MTSAAN--NGTSRREELLNVAAK
TH_0160|M.thermoresistible__bu      -------------------------------------MTRREELLAVATR
MMAR_0381|M.marinum_M               ---------------------------MPSET----GLSRREELLAVATK
MUL_4731|M.ulcerans_Agy99           ---------------------------MPSET----GLSRREELLAVATK
Mb0163|M.bovis_AF2122/97            ---------------------------MPSDTS-PNGLSRREELLAVATK
Rv0158|M.tuberculosis_H37Rv         ---------------------------MPSDTS-PNGLSRREELLAVATK
MAV_5138|M.avium_104                ---------------------------MPADSSTPNGQTRREELLAVATK
MAB_4574c|M.abscessus_ATCC_199      --------------------MQPVPEASKAGSSSQRRAGRREELVAVASK
MLBr_00815|M.leprae_Br4923          MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
                                                                           ** :*: **: 

Mflv_0719|M.gilvum_PYR-GCK          LFAARGYHGTRMDDVADAVGLNKATVYHYYASKSLILYDIYKGAADFTVD
Mvan_0126|M.vanbaalenii_PYR-1       LFAARGYHGTRMDDVADAVGLNKATVYHYYASKSLILYDIYKGAADFTVD
MSMEG_0120|M.smegmatis_MC2_155      LFAARGYHGTRMDDVAEAVGLNKATVYHYYASKSLILYDIYKSAADFTVE
TH_0160|M.thermoresistible__bu      LFAARGYHGTRMDDVADAIGLNKATVYHYYASKSLILYDIYRRAADSTVA
MMAR_0381|M.marinum_M               LFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTLG
MUL_4731|M.ulcerans_Agy99           LFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTLG
Mb0163|M.bovis_AF2122/97            LFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTLA
Rv0158|M.tuberculosis_H37Rv         LFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTLA
MAV_5138|M.avium_104                LFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILYDIYQQAAERTLA
MAB_4574c|M.abscessus_ATCC_199      LFAARGYHGTRMDDIADVAGLNKATVYHYFASKALILYEIYFKAAEETLA
MLBr_00815|M.leprae_Br4923          VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
                                    :*. :***.: **::*:  *:.*..:*::::**  :   :     :  : 

Mflv_0719|M.gilvum_PYR-GCK          ALHDDP--TASARETIYHFTRRLLVGIASDIERAAVYFQEGPYISEWFTE
Mvan_0126|M.vanbaalenii_PYR-1       ALHDDP--TATARETIYHFTRRLLVGIANDIERAAVYFQEGPYITEWFTE
MSMEG_0120|M.smegmatis_MC2_155      ALHDDP--TSSARETIYHFTRRLMVGIANDLERAAVYFQEGPYIAEWFTE
TH_0160|M.thermoresistible__bu      ALHDDP--NASAREMIYEFTRRLLVGIAGDIERAAVYFQEAPYITEWFTE
MMAR_0381|M.marinum_M               ALHAEP--SWTAREALYQYTVRLLTGIADNPERAAVYFQEQPYIAEWFTP
MUL_4731|M.ulcerans_Agy99           ALHAEP--SWTAREALYQYTVRLLTGIADNPERAAVYFQEQPYIAEWFTP
Mb0163|M.bovis_AF2122/97            AVHDDP--SWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTS
Rv0158|M.tuberculosis_H37Rv         AVHDDP--SWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTS
MAV_5138|M.avium_104                AVHDDP--SMTAREALYQYTVRLLDQIAANPEGAAVYFQEQPYITEWFTK
MAB_4574c|M.abscessus_ATCC_199      CLQDDP--RWSARESLYQCTSRMLALIFSNREQGAVYFQENPFLSEWLSP
MLBr_00815|M.leprae_Br4923          SVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFEND----NITEP
                                    .::       . *: ::  .  ::  *  : :   : *::     :    

Mflv_0719|M.gilvum_PYR-GCK          EQVDYIREKEAQVYEHVRDVIDRGIASGEFNDCDSHVLALGYIGMTLGSY
Mvan_0126|M.vanbaalenii_PYR-1       EQVEYIREKETQVYEHVRDVIDRGIASGEFYDCDSHVLALGYIGMTLGSY
MSMEG_0120|M.smegmatis_MC2_155      EQVEYIRHSEAQVYEHVRDVIDRGIASGEFYDCDSHVLALGYIGMVLGAY
TH_0160|M.thermoresistible__bu      EQVAYIRESEAKVYEHVRDVIDRGIASGEFYECDSHVLALGYIGMTLGSY
MMAR_0381|M.marinum_M               EQVAEVREKEAQVHEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSY
MUL_4731|M.ulcerans_Agy99           EQVAEVREKEAQVHEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSY
Mb0163|M.bovis_AF2122/97            EQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSY
Rv0158|M.tuberculosis_H37Rv         EQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSY
MAV_5138|M.avium_104                EQVAAVREKETQVYEHVHGLIDRGIASGEFYECDSHVLALGYIGMTLGAY
MAB_4574c|M.abscessus_ATCC_199      EQVAEIRTREDMVQERVQNIIERGIASGEFVECDSHVMALGYIGMVLGSY
MLBr_00815|M.leprae_Br4923          RVAAQVRVATESCIDAVFALIS---ADSRLDPHRARMVAVGLVGISVDCA
                                    . .  :*       : *  :*.   *...:    ::::*:* :*: :.. 

Mflv_0719|M.gilvum_PYR-GCK          RWLRPHGRRTAQEIAVEFSSALLRGLIRDETVRATSPLGVGIDVTAKQ--
Mvan_0126|M.vanbaalenii_PYR-1       RWLRPHGRRTAQEIAVEFSTALLRGLIRDETVRTLSPLGVGIDAPVKTRI
MSMEG_0120|M.smegmatis_MC2_155      RWLRPHGRRTAKEIAVEFSTALLRGLIRDENIRVESPLGIDVQAGSEEQR
TH_0160|M.thermoresistible__bu      RWLRPDGRRTAEEIAEEFSTALLRGLIRDEKIRADFPHGTGESEAEPANP
MMAR_0381|M.marinum_M               RWLRPHGRRTAREIAAEFSTALLRGLIRDESIRNQSPLGS----------
MUL_4731|M.ulcerans_Agy99           RWLRPHGRRTAREIAAEFSTALLRGLIRDESIRNQSPLGS----------
Mb0163|M.bovis_AF2122/97            RWLRPSGRRTAKEIAAEFSTALLRGLIRDESIRNQSPLGTRKET------
Rv0158|M.tuberculosis_H37Rv         RWLRPSGRRTAKEIAAEFSTALLRGLIRDESIRNQSPLGTRKET------
MAV_5138|M.avium_104                RWLRPSGRRSAKEIAAEFSTALLRGLIRDEEIRTTSPLGP----------
MAB_4574c|M.abscessus_ATCC_199      RWLNPSGRRSAQEIAVEFSTTLLRGLIRDEATRINDPLGVASATSLDGAR
MLBr_00815|M.leprae_Br4923          RYWLDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL---------------
                                    *:    .*  :.. * * :  :  * : .                     

Mflv_0719|M.gilvum_PYR-GCK          -----
Mvan_0126|M.vanbaalenii_PYR-1       LEEPS
MSMEG_0120|M.smegmatis_MC2_155      -----
TH_0160|M.thermoresistible__bu      AG---
MMAR_0381|M.marinum_M               -----
MUL_4731|M.ulcerans_Agy99           -----
Mb0163|M.bovis_AF2122/97            -----
Rv0158|M.tuberculosis_H37Rv         -----
MAV_5138|M.avium_104                -----
MAB_4574c|M.abscessus_ATCC_199      -----
MLBr_00815|M.leprae_Br4923          -----