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MASDVSTGLTKAARGRQVSQWTPREVELLKVTLRLLQEHGYDRLSVDEVAAESKASKATIYRRWPSKAEL VLAAFIEGMRAQLVRPNTGSLREDLLRIGTNALADVRRNTPVMRGLLIEIERNPALTKAFRTKFVDERKA LIDDVLFAAVQRGEIDADAVNEELWDLLPGYLVFRSLLPVRSPTADTVRTLVDDVIMPSLTRER
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0989 | - | - | 100% (204) | putative HTH-type transcriptional regulator TetR |
| M. abscessus ATCC 19977 | MAB_1497c | - | 1e-16 | 35.33% (184) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4749c | - | 4e-16 | 32.43% (185) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1581 | - | 9e-66 | 63.35% (191) | regulatory protein |
| M. gilvum PYR-GCK | Mflv_3021 | - | 6e-56 | 57.14% (182) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1556 | - | 9e-66 | 63.35% (191) | regulatory protein |
| M. leprae Br4923 | MLBr_01070 | - | 8e-05 | 40.62% (64) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_1695 | - | 7e-64 | 61.26% (191) | regulatory protein |
| M. avium 104 | MAV_3866 | - | 7e-61 | 58.42% (190) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3834 | - | 1e-17 | 39.18% (171) | putative TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_4110 | - | 4e-14 | 30.15% (199) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_1934 | - | 5e-64 | 61.26% (191) | regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_2727 | - | 3e-16 | 30.54% (167) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1581|M.bovis_AF2122/97 -----MVGAVTQ---IADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLT
Rv1556|M.tuberculosis_H37Rv -----MVGAVTQ---IADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLT
MMAR_1695|M.marinum_M ---------MTQ---TADRSAQVSPWSPREAELLAVTLQLLQEHGYDRLT
MUL_1934|M.ulcerans_Agy99 ------MGAMTQ---TADRSAQVSPWSPREAELLAVTLQLLQEHGYDRLT
MAV_3866|M.avium_104 ---------MTQ---TADRCEQASPWSPREAEILAVTLRLLQEHGYDQLT
MAB_0989|M.abscessus_ATCC_1997 -----MASDVSTGLTKAARGRQVSQWTPREVELLKVTLRLLQEHGYDRLS
Mflv_3021|M.gilvum_PYR-GCK ------MCVVSDPRSDPPSAPLKSRRTAREAQLLTITLQQLQQHGYDRLT
Mvan_2727|M.vanbaalenii_PYR-1 --------------------MGRRRGAELDAAIRAAVLELLAEHGPDGVT
MSMEG_3834|M.smegmatis_MC2_155 ------------------MTAGRPQEARVTTVILDAVLSELAEHGFGSMT
TH_4110|M.thermoresistible__bu ------VTATDAAATGRAAARGRPRDPALDSAILDAALEIFVEQGISALS
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLAERPLGDFS
: . : :: . .:
Mb1581|M.bovis_AF2122/97 VDAVAASARASKATVYRRWPSKAELVLAAFIEG-IRQVAVPPN-TGNLRD
Rv1556|M.tuberculosis_H37Rv VDAVAASARASKATVYRRWPSKAELVLAAFIEG-IRQVAVPPN-TGNLRD
MMAR_1695|M.marinum_M IDAVANTARASKATVYRRWPSKAELVLAAFIEG-VRQVAVAPN-TGSLRD
MUL_1934|M.ulcerans_Agy99 IDAVANTARASKATVYRRWPSKAELVLAAFIEG-VRQVAVAPN-TGSLRD
MAV_3866|M.avium_104 VDAVAGAAHASKATVYRRWPSKAELVLAAFIEG-VRQVAVPPN-TGTLRG
MAB_0989|M.abscessus_ATCC_1997 VDEVAAESKASKATIYRRWPSKAELVLAAFIEG-MRAQLVRPN-TGSLRE
Mflv_3021|M.gilvum_PYR-GCK VEAVATQAKASKATLYRRWPSKSDLVLAAFVEG-TRLAAVPPR-TGSLRD
Mvan_2727|M.vanbaalenii_PYR-1 MDAVAVTAQTSKPVLYRRWPDRRALLRDTLLGI-ATSAFPTVD-TGGFRG
MSMEG_3834|M.smegmatis_MC2_155 VDGVAKRAGAGKGAIYRRWPSKIEMTAAAMRTL-ALPEGAAPD-TGSLYG
TH_4110|M.thermoresistible__bu IEQVARRAGVGKPTIYRRWSDKEQLVADAIEHR-VSAELAWPTPAEASVS
MLBr_01070|M.leprae_Br4923 VDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVEALAEQLPA
:: :* : .: ..* :..: : : :
Mb1581|M.bovis_AF2122/97 DLLRLG-ELICREVGQHASTIR-AVLVEVS-----RNPALNDVLQHQFVD
Rv1556|M.tuberculosis_H37Rv DLLRLG-ELICREVGQHASTIR-AVLVEVS-----RNPALNDVLQHQFVD
MMAR_1695|M.marinum_M DLVKIG-EGICGQAHQQASTIR-AVLVEVS-----RHPALSDALQRQFVD
MUL_1934|M.ulcerans_Agy99 DLVKIG-EGICGQAHQQASTIR-AVLVEVS-----RHPALSDALQRQFVD
MAV_3866|M.avium_104 DLLALG-ETVCEQVGHHASTIR-AVMFEVS-----RHPALNDALQHQFLD
MAB_0989|M.abscessus_ATCC_1997 DLLRIG-TNALADVRRNTPVMR-GLLIEIE-----RNPALTKAFRTKFVD
Mflv_3021|M.gilvum_PYR-GCK DLLRVG-ASVCQQACEHASTMR-AVLNEMS-----HNPDLRKAMQDEFVH
Mvan_2727|M.vanbaalenii_PYR-1 DMLAVLRAWAALFTGDSAALMR-SAIGAVT-----ADPELAATFRTDVIG
MSMEG_3834|M.smegmatis_MC2_155 DVLALLADVNRWIGDERMRRLYPDLLAEAQ-----RNPVLAEALMDTVGT
TH_4110|M.thermoresistible__bu DPYELVRRNISAAARTAADPAFRGLIAAIYGSAV-THPALLRTYWEHYIL
MLBr_01070|M.leprae_Br4923 DPAAVWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVRRLWSTVMQQWID
* : * .
Mb1581|M.bovis_AF2122/97 HRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQD
Rv1556|M.tuberculosis_H37Rv HRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQD
MMAR_1695|M.marinum_M QRKALIQQVLQQAVDRGEITQAAITDELWDLLPGYLIFRSIIPNRPPTPH
MUL_1934|M.ulcerans_Agy99 QRKALIQQVLQQAVDRGEITQAAITDELWDLLPGYLIFRSIIPNRPPTPH
MAV_3866|M.avium_104 QRRALIEHVLHQAVDRGEISADAISDELWDLLPGYLIFRSIVPTRPPSRR
MAB_0989|M.abscessus_ATCC_1997 ERKALIDDVLFAAVQRGEIDADAVNEELWDLLPGYLVFRSLLPVRSPTAD
Mflv_3021|M.gilvum_PYR-GCK QHKLVIDEVLAEAVQRGEIDATAISDEIYDLLPGYLVFRALVSARPPTLK
Mvan_2727|M.vanbaalenii_PYR-1 ARKQEMDAIITRGVQRGEVRADVPVDLVRELGQSVLWHRLLISGDPIDDE
MSMEG_3834|M.smegmatis_MC2_155 PRRARARDILDRAATRGELAPGADSELLVDAMGALVFWRLIALFRPVTSE
TH_4110|M.thermoresistible__bu PRRTAAIALLRRARDLGTVAADADLDVLVDMLAGAVTYRVLQP-EPPSAR
MLBr_01070|M.leprae_Br4923 YNTAAIQAERKCGVAP-DTIPAEDLAVALQLMTERVMAATFSDEKPLIPD
. . : : : .
Mb1581|M.bovis_AF2122/97 --TVQALVDDVILP-----SLTRSTG--
Rv1556|M.tuberculosis_H37Rv --TVQALVDDVILP-----SLTRSTG--
MMAR_1695|M.marinum_M --TVQLLVDDFIMP-----GLTQATG--
MUL_1934|M.ulcerans_Agy99 --TVQLLVDDFIMP-----GLTQATG--
MAV_3866|M.avium_104 --TVQALVDGFLIP-----GLTAR----
MAB_0989|M.abscessus_ATCC_1997 --TVRTLVDDVIMP-----SLTRER---
Mflv_3021|M.gilvum_PYR-GCK --SVRTLVDKVLLPSLGHRGLSKPDGQ-
Mvan_2727|M.vanbaalenii_PYR-1 --VVTRLVDEVLIP------VTRPYYEV
MSMEG_3834|M.smegmatis_MC2_155 --YLDRVARAICAF-----ARTGPV---
TH_4110|M.thermoresistible__bu --QLRCYLEVAYRQ----VGLLP-----
MLBr_01070|M.leprae_Br4923 KKVIDTLVHIWLAS------IYGS----
: