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M. abscessus ATCC 19977 MAB_4703c (-)

annotation: membrane protein MmpL
coordinates: 4811058 - 4813904
length: 948

SGRPPLLAGLIRRLSVPIILGWLGMIAIVTFAVPSLEQVGRESSVSLVPQAAPSFRAMQRMGEVFGESNS
DSVAMVVLEGQQPLDDEAHAYYDSLVRQLGADTTHVQHIQDYWGDPLTASGVQSGDGKSVYVQISLAGNQ
GQALANKSVEAVRSIVERSAPPPGVQAYVTGPAPLVTDMNDAGNSSIIKITAVTLVVIFTMLLFVYRSVM
TVILLLIMVGIQVQAARGIVAFLGDQGVIGLSTFSVNLLVSLGIAVGTDYGIFFTGRYQEARQCGEDRET
AFYTTYSGVAKVVVASGLTIAGAIFCLSFTRLPYFQTMGIPAAIGMAVAVAVAVTLVPAVISFGSRFGLF
EPKRRMMVRRWRWIGTATVRWPGPILAAACAVGLVGLLALPGYQTSYDDRLYVPQDIPANVGYAAAQRHF
PESRMTPDVMLLEADHDMRNPADFVVLHKLAKGLFAVPGISMVQSITRPEGSPIERTSIPFQISLQSAGM
LQILPFGKERVDDMLKQAEDTTKMINQMQHTYELMSNISGITNETVVMNRELTATVDRLRDYIANFDDFF
KPLRNYLYWEKHCETIPICFAIRSVFQALDGTDLLSERTHRILERVEEMNLYQRELIALFPPMITTMKSM
RAMMLTMHSTMSGIFSLIDQTAANASAMGKIYDGAQNDDSFYLPPEVFENEDFKRAMSLFFSPDGKAVRL
ILTYRGDPGTPDSLSRVNAVRLAAQEALKVTPLENATIHLAGTAATFKDLRDGSAYDLLIAGVAALCLIF
GIMLIMTRSFVAALVIVGTVALSLGAAFGLSVLIWQNILGIELHWLVLAMSVIILLAVGSDYNLLLVSRM
KEELGAGINTGIIRAMGGTGKVVTSAGLVFAFTMLSMVVSDLRVIGQVGSTIGIGLLFDTLVVRAFMTPA
IAALLGRWFWWPQRIRRRPAITSQAPAERRMRVLLDA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_4703c--100% (948)membrane protein MmpL
M. abscessus ATCC 19977MAB_4704c-0.065.28% (939) membrane protein MmpL
M. abscessus ATCC 19977MAB_4115c-0.064.42% (936) putative membrane protein, MmpL

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0458cmmpL40.063.38% (934) transmembrane transport protein MmpL4
M. gilvum PYR-GCKMflv_2705-0.058.94% (928) transport protein
M. tuberculosis H37RvRv0450cmmpL40.063.49% (934) transmembrane transport protein MmpL4
M. leprae Br4923MLBr_02378-0.062.21% (934) hypothetical protein MLBr_02378
M. marinum MMMAR_0094mmpL5_30.063.27% (931) transmembrane transport protein, MmpL5_3
M. avium 104MAV_3249-0.063.01% (930) Mmp14A protein
M. smegmatis MC2 155MSMEG_0381-0.064.40% (927) Mmp14a protein
M. thermoresistible (build 8)TH_3056-0.061.02% (939) PUTATIVE Mmp14a protein
M. ulcerans Agy99MUL_0757mmpL50.058.58% (927) transmembrane transport protein, MmpL5
M. vanbaalenii PYR-1Mvan_3833-0.058.86% (926) transport protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb0458c|M.bovis_AF2122/97           ----MSTKFANDSNTNARPEKPFIARMIHAFAVPIILGWLAVCVVVTVFV
Rv0450c|M.tuberculosis_H37Rv        ----MSTKFANDSNTNARPEKPFIARMIHAFAVPIILGWLAVCVVVTVFV
MLBr_02378|M.leprae_Br4923          ----MTVKCANDLDTHTKP--PFVARMIHRFAVPIILVWLAIAVTVSVFI
MMAR_0094|M.marinum_M               -------------MTIKRPVRQSLSCAIRRLSIPIVIGWIALSAYLTVGL
MSMEG_0381|M.smegmatis_MC2_155      --------MTEPATTQNREARPRIASFIRRFSVLIILAWIVVAALATFAI
TH_3056|M.thermoresistible__bu      --------MSVLDRVGVEPRRPRVASFIRRYSVLIILGWVALTVLATVAV
MAB_4703c|M.abscessus_ATCC_199      ----------------MSGRPPLLAGLIRRLSVPIILGWLGMIAIVTFAV
MAV_3249|M.avium_104                --------------------------------MFIILGWVALTLLVTFGV
MUL_0757|M.ulcerans_Agy99           MTATTTDTPTDVVPPAEHPPRPFIPRMIRTFAVPLILGWVLLIAVLNSVV
Mflv_2705|M.gilvum_PYR-GCK          --------MSSSRDRAALREPRSVARWIRRLAVPIILGWLLLAVALNALV
Mvan_3833|M.vanbaalenii_PYR-1       --------MRAHADR-DLRDPTPVARWIRRLAIPIILGWVLLVAALNLLV
                                                                    : ::: *: :    .  :

Mb0458c|M.bovis_AF2122/97           PSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVIIEGN--
Rv0450c|M.tuberculosis_H37Rv        PSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVIIEGN--
MLBr_02378|M.leprae_Br4923          PSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGNSDSVIMIVLEGD--
MMAR_0094|M.marinum_M               PPLEVVGQLHSVSMNPRDAPSAVAMRRIGELFKESDSDNTAMILLEGD--
MSMEG_0381|M.smegmatis_MC2_155      PPLEVVEREHSVSLSPPDAPSVQAMKRMGEVFQESNSNSVAVLVLEGQ--
TH_3056|M.thermoresistible__bu      PPLEAVEREKSLSLIPYDAPAFAAMHRMGELFDEPDSESIAIIVLEGQ--
MAB_4703c|M.abscessus_ATCC_199      PSLEQVGRESSVSLVPQAAPSFRAMQRMGEVFGESNSDSVAMVVLEGQ--
MAV_3249|M.avium_104                PRLEIVGQQHSVPLAPQDAPAVQAMQRMGRDFKESDSDSFAMLVLEGQ--
MUL_0757|M.ulcerans_Agy99           PQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAMIVLEGQ--
Mflv_2705|M.gilvum_PYR-GCK          PQLEVVAAKNAVSMSPSNAPSMQAMADMGRLFEESDSDSIALIVLESETD
Mvan_3833|M.vanbaalenii_PYR-1       PQLEVVAAQNAVSMSPSDAPAMQAMSDMGRLFGESDSDSIAMVVLEGE--
                                    * ** *    ::.: *  **:  :*  :*  * * :*:.  ::::*.:  

Mb0458c|M.bovis_AF2122/97           QPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSNDGKAAY
Rv0450c|M.tuberculosis_H37Rv        QPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSNDGKAAY
MLBr_02378|M.leprae_Br4923          KPLGDDAHRFYDGLIRKLRADK-HVQSVQDFWGDPLTAPGAQSNDGKAAY
MMAR_0094|M.marinum_M               QPLGDNAHYYYNNLVRQLSSDTTHVQHIQNFWGDPLTAEGAQSTDGKAAY
MSMEG_0381|M.smegmatis_MC2_155      EPLGDDAHRYYDEIIRKLKDDPEHVQHVQDFWGDPLTAGAAESGDRKAAY
TH_3056|M.thermoresistible__bu      EPLGLEAHEYYDQLISQLREHPQYVQHIRDFWGDPLTAGAAQSDDGKAAF
MAB_4703c|M.abscessus_ATCC_199      QPLDDEAHAYYDSLVRQLGADTTHVQHIQDYWGDPLTASGVQSGDGKSVY
MAV_3249|M.avium_104                QQLGDDAHAYYDKLVRELRNDTKHVEHVQDLWGDRLTQAGAQSPDGKAVY
MUL_0757|M.ulcerans_Agy99           EPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQSGDGKAAY
Mflv_2705|M.gilvum_PYR-GCK          QPLGDDAHEYYDGLIAALLADTENVRNIQDTWGDPLTEAAAQSSDGRAAY
Mvan_3833|M.vanbaalenii_PYR-1       QPLGDDAHAYYDQLIEKLEAAPDHVRNIQDMWGDPLTEAAAQSTDGHAAY
                                    : *.  ** :*: ::  *      *. ::: *** **  ..:* * ::.:

Mb0458c|M.bovis_AF2122/97           VQLSLAGNQGTPLANESVEAVRSIVESTPAPPGIKAYVTGPSALAADMHH
Rv0450c|M.tuberculosis_H37Rv        VQLSLAGNQGTPLANESVEAVRSIVESTPAPPGIKAYVTGPSALAADMHH
MLBr_02378|M.leprae_Br4923          VQLSLAGNQGELLAQESIDAVRKIVVQTPAPPGITAWVTGASALIADMHH
MMAR_0094|M.marinum_M               VQLNLAGNMGGPLANQSIEAVRQILARTPPPPGIKVYVTGPSALTADMSR
MSMEG_0381|M.smegmatis_MC2_155      VQINLHGSFGQAEANESVKAVQDAVESTPAPPGVQAFVTGPAAIVADMGE
TH_3056|M.thermoresistible__bu      VQVNLVGRFGQAKVNEAVRAVQEIVERTPAPEGVETFVTGPAALGADAGD
MAB_4703c|M.abscessus_ATCC_199      VQISLAGNQGQALANKSVEAVRSIVERSAPPPGVQAYVTGPAPLVTDMND
MAV_3249|M.avium_104                VQLNLAGNQGTTLGQESVAAVRDVIARIPPPAGLKAYVTGPAALFSDMQL
MUL_0757|M.ulcerans_Agy99           VQVKLAGNQGESLANESVEAVKTIVDSLQAPPGVKVYVTGSAALVADQQL
Mflv_2705|M.gilvum_PYR-GCK          ATLNLAGNMGETESNEAVAAVRDIVANSPPPPGVTVHVTGPAALIADVNI
Mvan_3833|M.vanbaalenii_PYR-1       VALNLAGNMGETKSNESVAAVRDIVADSPPPPGVQVHVTGPAALTADVNI
                                    . :.* *  *    :::: **:  :    .* *: . ***.:.: :*   

Mb0458c|M.bovis_AF2122/97           SGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVELTAARGVVA
Rv0450c|M.tuberculosis_H37Rv        SGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVELTAARGVVA
MLBr_02378|M.leprae_Br4923          SGDKSMIRITATSVIVILVTLLLVYRSFITVILLLFTVGIESAVARGVVA
MMAR_0094|M.marinum_M               TGDKSLVIVTMISVLVIFTMLLLVYRSIVTVTLLLITVGIELTAARGVVA
MSMEG_0381|M.smegmatis_MC2_155      SGNKTVLLITLVTVGVIFLMLLLLYRRVLIVLILLATVAIELQVARGLVS
TH_3056|M.thermoresistible__bu      SGTATVILITLVTVAVIFLMLLFFFRSFLTVIVLLLTVAVELQVARGLVA
MAB_4703c|M.abscessus_ATCC_199      AGNSSIIKITAVTLVVIFTMLLFVYRSVMTVILLLIMVGIQVQAARGIVA
MAV_3249|M.avium_104                AGDRSILKMTLIGALIIFIVLLFVYRSVTTVVLLLLTVGIEVFAARGVIA
MUL_0757|M.ulcerans_Agy99           AGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIMLTMVVLGLLATRGGVA
Mflv_2705|M.gilvum_PYR-GCK          AGERSMALVLLVTFVVIIVLLLFFYRSISTVLLLLVVVGIQLLVARGVVA
Mvan_3833|M.vanbaalenii_PYR-1       AGESSMALILLVTFVVIIVLLLFFYRSITTVVLLLIMVGVQMSVARGVVA
                                    :*  ::  :      :*:  **:.:* .  . ::*  * :   .:** ::

Mb0458c|M.bovis_AF2122/97           VLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEARQAGEDKEAA
Rv0450c|M.tuberculosis_H37Rv        VLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEARQAGEDKEAA
MLBr_02378|M.leprae_Br4923          LLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFITGRYQEARQANENKEAA
MMAR_0094|M.marinum_M               FLAWHGVIGLSTYAINLLTTMAIAAGTDYSIFIIGRYQEARQAGEDAETA
MSMEG_0381|M.smegmatis_MC2_155      FLALNGIVGLTTYVVNLLVSVGIAAGTDYGIFFAGRYQEARQAGEDREQA
TH_3056|M.thermoresistible__bu      YLGLQGWVGLTTYVVNLLVSVGIAAGTDYGIFFFGRYQEAREAGEDRDSA
MAB_4703c|M.abscessus_ATCC_199      FLGDQGVIGLSTFSVNLLVSLGIAVGTDYGIFFTGRYQEARQCGEDRETA
MAV_3249|M.avium_104                FVANNNLMPLSTFAVNLLVALAMAAGTDYAIFFFGRYQEAREAGEDRATA
MUL_0757|M.ulcerans_Agy99           FLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEARGLGQDRESA
Mflv_2705|M.gilvum_PYR-GCK          ALAHVGVIGLSTYATNLLISLAVAAGTDYAIFLVGRYQEARASGADHEEA
Mvan_3833|M.vanbaalenii_PYR-1       ALGHFQVIGLSTFAVNLLISLAVAAGTDYAIFLVGRYQEARASGADPEAA
                                     :.    : *:*:  .**  :.:*..***.**: *******  . :   *

Mb0458c|M.bovis_AF2122/97           YYTMYRGTAHVILGSGLTITGATFCLSFARMPYFQTLGIPCAVGMLVAVA
Rv0450c|M.tuberculosis_H37Rv        YYTMYRGTAHVILGSGLTIAGATFCLSFARMPYFQTLGIPCAVGMLVAVA
MLBr_02378|M.leprae_Br4923          FYTMYRGTFHVILGSGLTISGATFCLSFARMPYFQTLGVPCAVGMLIAVA
MMAR_0094|M.marinum_M               FYTMYRGVAHVILGSGLTIAGAMYCLTFTRMPYFQSMGIPCAAGMLVAVV
MSMEG_0381|M.smegmatis_MC2_155      YYTSFAGVAKVVLASGATIAGAIACLSFTRLPYFQPLGIPGAVGIGVAVA
TH_3056|M.thermoresistible__bu      YFTTYRSVAKVVLASGLTIAGAIACLSFTRLPHFQPLGIPGAVGLLVAVA
MAB_4703c|M.abscessus_ATCC_199      FYTTYSGVAKVVVASGLTIAGAIFCLSFTRLPYFQTMGIPAAIGMAVAVA
MAV_3249|M.avium_104                YFTTYRSVAPVVLGSGLTIAGAMLCLSFTRMPIFQTMGLPCSVGMLISVF
MUL_0757|M.ulcerans_Agy99           YYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPLAIGMVIVVA
Mflv_2705|M.gilvum_PYR-GCK          YYEMFHGTAHVVLGSGLTIAGAMLCLSFTRMPYFQSMGIPCAVGIAAGVA
Mvan_3833|M.vanbaalenii_PYR-1       YYEMFGGTAHVVLGSGLTIAGAMYCLSFARMPYFQSMGVPCAVGILAGVA
                                    ::  : ..  *::.** **:**  **:*:*:* **.:*:* : *:   * 

Mb0458c|M.bovis_AF2122/97           VALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVGTVVVRWPLPVLVATC
Rv0450c|M.tuberculosis_H37Rv        VALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVGTVVVRWPLPVLVATC
MLBr_02378|M.leprae_Br4923          VALTLGPAVLTVGSRFG-LFEPKRLIKVRGWRRIGTVVVRWPLPILITTC
MMAR_0094|M.marinum_M               AALTMGPAVLALGSRFG-LFDPKRKIKTRGWRRIGTAVVRWPAPILTATC
MSMEG_0381|M.smegmatis_MC2_155      VALTLVPACIAATNRFG-WFDPRRLVTTRRWRRIGTAVVRWPAPILIATI
TH_3056|M.thermoresistible__bu      VALTLVPATIALGSRFG-LFEPKRRVMTHRWRRIGTAVVRWPVPILTAAV
MAB_4703c|M.abscessus_ATCC_199      VAVTLVPAVISFGSRFG-LFEPKRRMMVRRWRWIGTATVRWPGPILAAAC
MAV_3249|M.avium_104                IALTLVPAVLTVGGGFG-LFDPKRAIGFGRWRRIGTAIVRWPAPILTATI
MUL_0757|M.ulcerans_Agy99           TALTLGPALIAVMSRFGKLLEPKRMARVRGWRKIGAAIVRWPGPILIGAV
Mflv_2705|M.gilvum_PYR-GCK          VALTLGPAIVTVGSRFN-LLEPKRAMRIRAWRRIGTMVVRWPGPILVASL
Mvan_3833|M.vanbaalenii_PYR-1       VALTLGPAIVTVGSRFG-LLEPKRAMRIRAWRRVGATVVRWPGPILVASL
                                     *:*: ** :   . *.  ::*:*      ** :*:  **** *:*  : 

Mb0458c|M.bovis_AF2122/97           AIALVGLLALPGYKTSYNDRDYLPDFIPANQGYAAADRHFSQARMK-PEI
Rv0450c|M.tuberculosis_H37Rv        AIALVGLLALPGYKTSYNDRDYLPDFIPANQGYAAADRHFSQARMK-PEI
MLBr_02378|M.leprae_Br4923          AIAMVGLLALPGYRTNYKDRAYLPASIPANQGFAAADRHFPQARMK-PEI
MMAR_0094|M.marinum_M               AVSLVGLIALPGYQTNYDDQTYVPENIPANAGYAAANRHFPPSRMK-PDV
MSMEG_0381|M.smegmatis_MC2_155      AVAVIGLLTLPGYNPSYSDQKYIPQDIPANQGFAAAARHFPESKMTTPDI
TH_3056|M.thermoresistible__bu      ALSLVGLLTLPGYNPSYSDQEFIPDDIPASEGYKAAARHFPASAMSVPDV
MAB_4703c|M.abscessus_ATCC_199      AVGLVGLLALPGYQTSYDDRLYVPQDIPANVGYAAAQRHFPESRMT-PDV
MAV_3249|M.avium_104                AVALVGLVTLPGYKTSYNNRLYMPDSVPANVGYAAADRHFTQSRMM-PEL
MUL_0757|M.ulcerans_Agy99           ALALVGLLTLPGYKTNYNDRNYLPADLPANEGYSAAERHFSQARMN-PEV
Mflv_2705|M.gilvum_PYR-GCK          ALALVGLAALPGYQTSYDDTRYVPESIPANAGLQAATQHFTLSRMS-PEI
Mvan_3833|M.vanbaalenii_PYR-1       ALALIGLAALPGYKTSYDDTRYIPESIPANAGLQAATKYFSLSRMS-PEV
                                    *:.::** :****...*.:  ::*  :**. *  ** ::*. : *  *::

Mb0458c|M.bovis_AF2122/97           LMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAITRPEGTTMDHTSI
Rv0450c|M.tuberculosis_H37Rv        LMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAITRPEGTTMDHTSI
MLBr_02378|M.leprae_Br4923          LMIESDHDMRNPADFLILDKLARGIFRVPGISRVQAITRPDGTAMDHTSI
MMAR_0094|M.marinum_M               LLIVADHDMRNSADFLVLDKLAKGIFHVPGISRVQAITRPKGTPIEHTSI
MSMEG_0381|M.smegmatis_MC2_155      LLVEADHDMRNSADLLVLNKLAKAVFAVPGVSNVQAITRPEGTPIEHTSI
TH_3056|M.thermoresistible__bu      VLIEADRDMRNPADLLVLNKVAKKIFEVPGVANVQSVTRPEGRQIEHTTI
MAB_4703c|M.abscessus_ATCC_199      MLLEADHDMRNPADFVVLHKLAKGLFAVPGISMVQSITRPEGSPIERTSI
MAV_3249|M.avium_104                LMIESDHDMRNPADFLVLHRLAKGVFGVHGISRVQGITRPEGTPIQHTSI
MUL_0757|M.ulcerans_Agy99           LMVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQAITRPDGKPIEHTSI
Mflv_2705|M.gilvum_PYR-GCK          LIVEADRDLRNPADFLVLDRLAKRVFAVEGVARVQAPSRPDGSPIAKTSI
Mvan_3833|M.vanbaalenii_PYR-1       LIVEADRDLRNSSDFLILDRLAKRVFNVEGVARVQAPSRPDGAPIAHTSI
                                    ::: :*:*:**.:*::::.::*: :* * *:: **. :**.*  : :*:*

Mb0458c|M.bovis_AF2122/97           PFQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTRMHSLMAEMA
Rv0450c|M.tuberculosis_H37Rv        PFQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTRMHSLMAEMA
MLBr_02378|M.leprae_Br4923          PFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAETIASMRRMHQLMALLT
MMAR_0094|M.marinum_M               PFQISMQNAGQLQNMKYQRDRMNDMLTQADQLTSTIALMKRTYDLMLQMS
MSMEG_0381|M.smegmatis_MC2_155      PFMLSMSNASQRLSLPFQQQRMEDLLKQADELTKNIALMKHMYALMQEMV
TH_3056|M.thermoresistible__bu      PFMLSMSQASQRLALPFQRARMDDMLKQADELTETIALMRRMQSLMEKMV
MAB_4703c|M.abscessus_ATCC_199      PFQISLQSAGMLQILPFGKERVDDMLKQAEDTTKMINQMQHTYELMSNIS
MAV_3249|M.avium_104                PFLLSMQQATMHQDIQYMKARMDDMLVQADLMRKQIEIMRHIYELQKRLT
MUL_0757|M.ulcerans_Agy99           PFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNIDQMERMHDLTQQMA
Mflv_2705|M.gilvum_PYR-GCK          PFLISMQGVGQQQNMKLMQDRMDDMRTQADNLGKTLGTMRTMYGLMTRLS
Mvan_3833|M.vanbaalenii_PYR-1       PFLISMQGVGQQQNMKLMKDRIADMRVQADDIGETIATMKTMYGLMTKFS
                                    ** :*:. .         :    .:  *.:     :  :     *   : 

Mb0458c|M.bovis_AF2122/97           STTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWEKHCYGIPIC
Rv0450c|M.tuberculosis_H37Rv        STTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWEKHCYGIPIC
MLBr_02378|M.leprae_Br4923          ENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPIRSYFYWERHCFNIPIC
MMAR_0094|M.marinum_M               KTTHRMVGDTLEMKSVTDELRDHIADFEDTWRPIRSYFYWEKHCADIPIC
MSMEG_0381|M.smegmatis_MC2_155      ATTHSTVETTHEVQQTTKDLRDSIEDFQDFWRPIRNYLYWEPHCYDIPLC
TH_3056|M.thermoresistible__bu      ATTHSMVGTTHELLDTTRDLRDHIADFDDFFRPIRNYFHWEPHCYNIPIC
MAB_4703c|M.abscessus_ATCC_199      GITNETVVMNRELTATVDRLRDYIANFDDFFKPLRNYLYWEKHCETIPIC
MAV_3249|M.avium_104                DITHDSIVKTKEMAAVLWELRDKMSDFEDFWRPLRSYFYWEKHCYDIPIC
MUL_0757|M.ulcerans_Agy99           DVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRSYFYWEKHCFDIPVC
Mflv_2705|M.gilvum_PYR-GCK          EVTTVMIDDFTEMQQTVHQIRDMVANFDDQFRPVRNYFYWEPHCYNIPLC
Mvan_3833|M.vanbaalenii_PYR-1       NITTVMIDDMTEMRDTVHQIRDMVATFDDQFRPIRNYFYWEPHCYNIPLC
                                      *   :     :      :*: :  *:* ::*:*.*::** **  **:*

Mb0458c|M.bovis_AF2122/97           WSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQIPPQIEAMEN
Rv0450c|M.tuberculosis_H37Rv        WSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQIPPQIEAMEN
MLBr_02378|M.leprae_Br4923          WSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMPQMLEQFPPMIESMES
MMAR_0094|M.marinum_M               WSLRSIFDALDGVDQVSEQLTTLTGDLTDMDRILPQVVATFPQMIQNMEG
MSMEG_0381|M.smegmatis_MC2_155      WSIRSLFDGLDGINEVTDKMGDLVEDLDHLDTLMPQMLLQFPPMIAMLEN
TH_3056|M.thermoresistible__bu      WSIRSIFDALDGINEMTEKMEELVEDMDRLDALMPQMLVQFPQMIETMES
MAB_4703c|M.abscessus_ATCC_199      FAIRSVFQALDGTDLLSERTHRILERVEEMNLYQRELIALFPPMITTMKS
MAV_3249|M.avium_104                WSLRNIFETLDGVDTLSDKMTYLLQDLDHMDRLMPQLLEQYPPMIAMSED
MUL_0757|M.ulcerans_Agy99           WSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQMTAMMPEMIQTMKS
Mflv_2705|M.gilvum_PYR-GCK          WSFRSLFDSMDGISTMTESFDKALVNMETMRSLLPQMLATFPPMIETMES
Mvan_3833|M.vanbaalenii_PYR-1       WSFRSLFDSMDGISVMTDTFDKAVANMDEMKALLPQMLATFPPMIETMES
                                    :::*.:*: :** . : :        :  :     ::    *  *   :.

Mb0458c|M.bovis_AF2122/97           MRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAAKNDDSFYLPPEVFK
Rv0450c|M.tuberculosis_H37Rv        MRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAAKNDDSFYLPPEVFK
MLBr_02378|M.leprae_Br4923          MRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFDTAKNDDSFYLPPEVFK
MMAR_0094|M.marinum_M               MRTLILTMHSTMSGIYDQMDELSKNSTAMGQAFDAAKNDDSFYLPPEVFN
MSMEG_0381|M.smegmatis_MC2_155      SRSMILTMHSTMSGIFSQMDDSTDNATAMGKAFDAARNDDSFYLPPDILE
TH_3056|M.thermoresistible__bu      SRTMILTMHATMSGIFDQMESSSENATAMGKAFDASHNDDSFYLPPEALE
MAB_4703c|M.abscessus_ATCC_199      MRAMMLTMHSTMSGIFSLIDQTAANASAMGKIYDGAQNDDSFYLPPEVFE
MAV_3249|M.avium_104                MLRMMLTNHSTMSGIIGQMDSNNKDATAMGEAFDASKNDDSFYLPPDIFD
MUL_0757|M.ulcerans_Agy99           MKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDSSRNDDSFYLPPEVFN
Mflv_2705|M.gilvum_PYR-GCK          MRQMMLTTYATMGGFYDQMDELTQDSTEMGKAFDEAKNDDSFYLPPEVFE
Mvan_3833|M.vanbaalenii_PYR-1       MRQMMLTTYATMGGFYDQMDELTRDSTEMGKAFDAAKNDDSFYLPPEVFE
                                        :*: ::*  *: . :     ::. **: :* ::*********: :.

Mb0458c|M.bovis_AF2122/97           NKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGIKSIDAIRTAAEESLK
Rv0450c|M.tuberculosis_H37Rv        NKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGIKSIDAIRTAAEESLK
MLBr_02378|M.leprae_Br4923          NTDFKRAMKSFLSSDGHAARFIILHRGDPASVAGIASINAIRTAAEEALK
MMAR_0094|M.marinum_M               NPDFKRGMKMFLSQDGKAARLFIFHRGNAAGYEGISSISAINIAAAEALK
MSMEG_0381|M.smegmatis_MC2_155      NEDFKRVMKIFMSPDGKAARMLITQRGDPATPEGIALVEPIRVAAEEALK
TH_3056|M.thermoresistible__bu      NKDFQRVMEIFLSPDGKAARMLVTQRGDPATPEGMALVEPIYIAAEEALK
MAB_4703c|M.abscessus_ATCC_199      NEDFKRAMSLFFSPDGKAVRLILTYRGDPGTPDSLSRVNAVRLAAQEALK
MAV_3249|M.avium_104                NADFKKAMSQFLSPDGKAARFIISHRGDPATSEALNRIDKIRSAAEEALK
MUL_0757|M.ulcerans_Agy99           NPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAGINHIDKIKTAAKEAIK
Mflv_2705|M.gilvum_PYR-GCK          NEDFKRAMESFFSPDGKTVRMLVSHRGDPTTPEALARVEPIKIAAIEALK
Mvan_3833|M.vanbaalenii_PYR-1       NEDFKRAMESFFSPDGKTVRMLIAHRGNPTTDEALQRVEPIKIAAIEALK
                                    * **:: :. *:* **::.*:::  .*:.    .:  :. :  ** *::*

Mb0458c|M.bovis_AF2122/97           GTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLCLIFIIMLIITRA
Rv0450c|M.tuberculosis_H37Rv        GTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLCLIFIIMLIITRA
MLBr_02378|M.leprae_Br4923          GTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGISSLCLIFIIMLIITRA
MMAR_0094|M.marinum_M               GTPLEDAQIYLTGTAAVYKDIADGSKYDLIIAGLSSLCLIFIIMLLITRG
MSMEG_0381|M.smegmatis_MC2_155      GTPLESAELHLAGTAAGVKDLVDGSKIDLLIAGVAALCLIFIIMLIMTRS
TH_3056|M.thermoresistible__bu      GTPLESSRIYLAGSAAGVKDLVEGAKYDLMIAAISAVCLIFMIMVFMTRS
MAB_4703c|M.abscessus_ATCC_199      VTPLENATIHLAGTAATFKDLRDGSAYDLLIAGVAALCLIFGIMLIMTRS
MAV_3249|M.avium_104                NTPLENAKIYLAGTASTFKDFRDGSTYDLFIAGVGALCLIFIIMLILTRS
MUL_0757|M.ulcerans_Agy99           GTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGISALCLIFIIMLIITRS
Mflv_2705|M.gilvum_PYR-GCK          GTPLENAQIQLGGTAATFKDMSDGSRYDMMIAILSALCLVLVIMLVLTRS
Mvan_3833|M.vanbaalenii_PYR-1       GTPLENAQIQLGGTAATFKDMSDGSRYDLLIAVISALCLVLMIMLVLTRS
                                     ****.: : * *:.:  :*: :*   *:.** :.::**:: **:.:**.

Mb0458c|M.bovis_AF2122/97           FIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLAMSVIVLLAVG
Rv0450c|M.tuberculosis_H37Rv        FIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLAMSVIVLLAVG
MLBr_02378|M.leprae_Br4923          FVAAAVIVGTVALSLGASFGLSVLLWQHILGIELHYLVLAMSVIVLLAVG
MMAR_0094|M.marinum_M               FVAALVIVGTVALSLGVSFGLSVLLWQHLLRIELHWLVLAMSVIVLLAVG
MSMEG_0381|M.smegmatis_MC2_155      FIAALVIVGTVAMSLGASFGLSVLVWQHLLGIQINWVVLAMSVIVLLAVG
TH_3056|M.thermoresistible__bu      VIAALVIVGTVVLSLGASFGMSVLLWQHLLGIQLHWVVLAMSVIVLLAVG
MAB_4703c|M.abscessus_ATCC_199      FVAALVIVGTVALSLGAAFGLSVLIWQNILGIELHWLVLAMSVIILLAVG
MAV_3249|M.avium_104                FIAALVIVGTVTLSLGASFGLSVLIWQYIFGIQLYWMVLPMSVIVLLAVG
MUL_0757|M.ulcerans_Agy99           VVAAAVIVGTVVLSLGASFGLSVLIWQHVLGIELHWLVLAMAVIILLAVG
Mflv_2705|M.gilvum_PYR-GCK          LVAAVVIVGTVALSLGASFGVSVLIWQHLLGVELHWMVLVMSIIALIAVG
Mvan_3833|M.vanbaalenii_PYR-1       LVAALVIVGTVTLSLGASFGISILIWQHIVGIELHWMVLALSIIALIAVG
                                    .:** ******.:***.:**:*:*:** :. :.: ::** :::* *:***

Mb0458c|M.bovis_AF2122/97           SDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTNAGLVFAVTMASMAV
Rv0450c|M.tuberculosis_H37Rv        SDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTNAGLVFAVTMASMAV
MLBr_02378|M.leprae_Br4923          SDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVVTNAGLVFAFTMASMVV
MMAR_0094|M.marinum_M               SDYNLLLVSRLKEEVGAGIKTGIIRAMGGTGKVVTSAGLVFALTMASMAV
MSMEG_0381|M.smegmatis_MC2_155      SDYNLLLVSRMKEEIGAGLNTGIIRAMGGTGKVVTAAGLVFAATMASMIV
TH_3056|M.thermoresistible__bu      SDYNLMLVSRMKEEIGAGLNTGIIRAMGGTGRVVTMAGLVFAATMASMIV
MAB_4703c|M.abscessus_ATCC_199      SDYNLLLVSRMKEELGAGINTGIIRAMGGTGKVVTSAGLVFAFTMLSMVV
MAV_3249|M.avium_104                SDYNLLLVSRMKEEISAGINTGIIRAMGGTGKVVTNAGLVFAFTMASMVV
MUL_0757|M.ulcerans_Agy99           ADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAGLVFAFTMMSFAV
Mflv_2705|M.gilvum_PYR-GCK          SDYNLLLVSRFKEEIGAGIKTGIIRAIGGTGSVVSVAGVVFALTMASMVV
Mvan_3833|M.vanbaalenii_PYR-1       SDYNLLLVSRFKEEIPAGIKTGIIRAIGGTGSVVTVAGVVFALTMASMVV
                                    :****:**:*:*:*: **::*****::**:* **: **:*** ** *: *

Mb0458c|M.bovis_AF2122/97           SDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFWWPLRVRSRP
Rv0450c|M.tuberculosis_H37Rv        SDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFWWPLRVRSRP
MLBr_02378|M.leprae_Br4923          SDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAALLGRWFWWPQQGRTRP
MMAR_0094|M.marinum_M               SDLIVIGQIGTTIGLGLLFDTLIVRSLMTPSIAALLGRWFWWPLNIRSRP
MSMEG_0381|M.smegmatis_MC2_155      SDLLTIGQVGTTIGLGLLFDTLVVRAFMTPSIAALLGRWFWWPQRVRQRP
TH_3056|M.thermoresistible__bu      SDLLMIGQVGTTIALGLLFDTMVVRAFMTPSVAAILGRWFWWPQRVRTRP
MAB_4703c|M.abscessus_ATCC_199      SDLRVIGQVGSTIGIGLLFDTLVVRAFMTPAIAALLGRWFWWPQRIRRRP
MAV_3249|M.avium_104                SDLRIIGQVGTTIGLGLMFDTLIVRSFMTPTIAALLGRWFWWPQLVRRRP
MUL_0757|M.ulcerans_Agy99           SELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGKWFWWPQVVRQRP
Mflv_2705|M.gilvum_PYR-GCK          SDLKVIAQVGTTIGLGLLFDTFIVRAFMMPSIATLLGRWFWWPLVVRSRP
Mvan_3833|M.vanbaalenii_PYR-1       SDLRVMAQVGTTIGLGLLFDTFIVRAFMMPAIATLLGRWFWWPLVVRSRP
                                    *:*  :.*:*:**.:**:***::**::* *::*::**:*****   * **

Mb0458c|M.bovis_AF2122/97           ARTPTVPSETQPAGRPLAMSSDRLG-------------
Rv0450c|M.tuberculosis_H37Rv        ARTPTVPSETQPAGRPLAMSSDRLG-------------
MLBr_02378|M.leprae_Br4923          LLTVAAPVGLPPD-RSLVYSD-----------------
MMAR_0094|M.marinum_M               PRLTRQRPLPSVSQEPAAARV-----------------
MSMEG_0381|M.smegmatis_MC2_155      ASAMLRSVGPRPLVRSLLLRD-----------------
TH_3056|M.thermoresistible__bu      ASAMLRPVGPRPLVRSLLLRD-----------------
MAB_4703c|M.abscessus_ATCC_199      AITSQAPAERR--MRVLLDA------------------
MAV_3249|M.avium_104                ASQLLRSEGTRRSVRVLLHQNDDADADTAEIPVPRPTA
MUL_0757|M.ulcerans_Agy99           APQPWPTPAPTPPPATTSV-------------------
Mflv_2705|M.gilvum_PYR-GCK          LRPRPQQQALGVGGQQG---------------------
Mvan_3833|M.vanbaalenii_PYR-1       LRLPPRT-------------------------------