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SGRPPLLAGLIRRLSVPIILGWLGMIAIVTFAVPSLEQVGRESSVSLVPQAAPSFRAMQRMGEVFGESNS DSVAMVVLEGQQPLDDEAHAYYDSLVRQLGADTTHVQHIQDYWGDPLTASGVQSGDGKSVYVQISLAGNQ GQALANKSVEAVRSIVERSAPPPGVQAYVTGPAPLVTDMNDAGNSSIIKITAVTLVVIFTMLLFVYRSVM TVILLLIMVGIQVQAARGIVAFLGDQGVIGLSTFSVNLLVSLGIAVGTDYGIFFTGRYQEARQCGEDRET AFYTTYSGVAKVVVASGLTIAGAIFCLSFTRLPYFQTMGIPAAIGMAVAVAVAVTLVPAVISFGSRFGLF EPKRRMMVRRWRWIGTATVRWPGPILAAACAVGLVGLLALPGYQTSYDDRLYVPQDIPANVGYAAAQRHF PESRMTPDVMLLEADHDMRNPADFVVLHKLAKGLFAVPGISMVQSITRPEGSPIERTSIPFQISLQSAGM LQILPFGKERVDDMLKQAEDTTKMINQMQHTYELMSNISGITNETVVMNRELTATVDRLRDYIANFDDFF KPLRNYLYWEKHCETIPICFAIRSVFQALDGTDLLSERTHRILERVEEMNLYQRELIALFPPMITTMKSM RAMMLTMHSTMSGIFSLIDQTAANASAMGKIYDGAQNDDSFYLPPEVFENEDFKRAMSLFFSPDGKAVRL ILTYRGDPGTPDSLSRVNAVRLAAQEALKVTPLENATIHLAGTAATFKDLRDGSAYDLLIAGVAALCLIF GIMLIMTRSFVAALVIVGTVALSLGAAFGLSVLIWQNILGIELHWLVLAMSVIILLAVGSDYNLLLVSRM KEELGAGINTGIIRAMGGTGKVVTSAGLVFAFTMLSMVVSDLRVIGQVGSTIGIGLLFDTLVVRAFMTPA IAALLGRWFWWPQRIRRRPAITSQAPAERRMRVLLDA*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_4703c | - | - | 100% (948) | membrane protein MmpL |
M. abscessus ATCC 19977 | MAB_4704c | - | 0.0 | 65.28% (939) | membrane protein MmpL |
M. abscessus ATCC 19977 | MAB_4115c | - | 0.0 | 64.42% (936) | putative membrane protein, MmpL |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0458c | mmpL4 | 0.0 | 63.38% (934) | transmembrane transport protein MmpL4 |
M. gilvum PYR-GCK | Mflv_2705 | - | 0.0 | 58.94% (928) | transport protein |
M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 63.49% (934) | transmembrane transport protein MmpL4 |
M. leprae Br4923 | MLBr_02378 | - | 0.0 | 62.21% (934) | hypothetical protein MLBr_02378 |
M. marinum M | MMAR_0094 | mmpL5_3 | 0.0 | 63.27% (931) | transmembrane transport protein, MmpL5_3 |
M. avium 104 | MAV_3249 | - | 0.0 | 63.01% (930) | Mmp14A protein |
M. smegmatis MC2 155 | MSMEG_0381 | - | 0.0 | 64.40% (927) | Mmp14a protein |
M. thermoresistible (build 8) | TH_3056 | - | 0.0 | 61.02% (939) | PUTATIVE Mmp14a protein |
M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 58.58% (927) | transmembrane transport protein, MmpL5 |
M. vanbaalenii PYR-1 | Mvan_3833 | - | 0.0 | 58.86% (926) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb0458c|M.bovis_AF2122/97 ----MSTKFANDSNTNARPEKPFIARMIHAFAVPIILGWLAVCVVVTVFV Rv0450c|M.tuberculosis_H37Rv ----MSTKFANDSNTNARPEKPFIARMIHAFAVPIILGWLAVCVVVTVFV MLBr_02378|M.leprae_Br4923 ----MTVKCANDLDTHTKP--PFVARMIHRFAVPIILVWLAIAVTVSVFI MMAR_0094|M.marinum_M -------------MTIKRPVRQSLSCAIRRLSIPIVIGWIALSAYLTVGL MSMEG_0381|M.smegmatis_MC2_155 --------MTEPATTQNREARPRIASFIRRFSVLIILAWIVVAALATFAI TH_3056|M.thermoresistible__bu --------MSVLDRVGVEPRRPRVASFIRRYSVLIILGWVALTVLATVAV MAB_4703c|M.abscessus_ATCC_199 ----------------MSGRPPLLAGLIRRLSVPIILGWLGMIAIVTFAV MAV_3249|M.avium_104 --------------------------------MFIILGWVALTLLVTFGV MUL_0757|M.ulcerans_Agy99 MTATTTDTPTDVVPPAEHPPRPFIPRMIRTFAVPLILGWVLLIAVLNSVV Mflv_2705|M.gilvum_PYR-GCK --------MSSSRDRAALREPRSVARWIRRLAVPIILGWLLLAVALNALV Mvan_3833|M.vanbaalenii_PYR-1 --------MRAHADR-DLRDPTPVARWIRRLAIPIILGWVLLVAALNLLV : ::: *: : . : Mb0458c|M.bovis_AF2122/97 PSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVIIEGN-- Rv0450c|M.tuberculosis_H37Rv PSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVIIEGN-- MLBr_02378|M.leprae_Br4923 PSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGNSDSVIMIVLEGD-- MMAR_0094|M.marinum_M PPLEVVGQLHSVSMNPRDAPSAVAMRRIGELFKESDSDNTAMILLEGD-- MSMEG_0381|M.smegmatis_MC2_155 PPLEVVEREHSVSLSPPDAPSVQAMKRMGEVFQESNSNSVAVLVLEGQ-- TH_3056|M.thermoresistible__bu PPLEAVEREKSLSLIPYDAPAFAAMHRMGELFDEPDSESIAIIVLEGQ-- MAB_4703c|M.abscessus_ATCC_199 PSLEQVGRESSVSLVPQAAPSFRAMQRMGEVFGESNSDSVAMVVLEGQ-- MAV_3249|M.avium_104 PRLEIVGQQHSVPLAPQDAPAVQAMQRMGRDFKESDSDSFAMLVLEGQ-- MUL_0757|M.ulcerans_Agy99 PQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAMIVLEGQ-- Mflv_2705|M.gilvum_PYR-GCK PQLEVVAAKNAVSMSPSNAPSMQAMADMGRLFEESDSDSIALIVLESETD Mvan_3833|M.vanbaalenii_PYR-1 PQLEVVAAQNAVSMSPSDAPAMQAMSDMGRLFGESDSDSIAMVVLEGE-- * ** * ::.: * **: :* :* * * :*:. ::::*.: Mb0458c|M.bovis_AF2122/97 QPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSNDGKAAY Rv0450c|M.tuberculosis_H37Rv QPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSNDGKAAY MLBr_02378|M.leprae_Br4923 KPLGDDAHRFYDGLIRKLRADK-HVQSVQDFWGDPLTAPGAQSNDGKAAY MMAR_0094|M.marinum_M QPLGDNAHYYYNNLVRQLSSDTTHVQHIQNFWGDPLTAEGAQSTDGKAAY MSMEG_0381|M.smegmatis_MC2_155 EPLGDDAHRYYDEIIRKLKDDPEHVQHVQDFWGDPLTAGAAESGDRKAAY TH_3056|M.thermoresistible__bu EPLGLEAHEYYDQLISQLREHPQYVQHIRDFWGDPLTAGAAQSDDGKAAF MAB_4703c|M.abscessus_ATCC_199 QPLDDEAHAYYDSLVRQLGADTTHVQHIQDYWGDPLTASGVQSGDGKSVY MAV_3249|M.avium_104 QQLGDDAHAYYDKLVRELRNDTKHVEHVQDLWGDRLTQAGAQSPDGKAVY MUL_0757|M.ulcerans_Agy99 EPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQSGDGKAAY Mflv_2705|M.gilvum_PYR-GCK QPLGDDAHEYYDGLIAALLADTENVRNIQDTWGDPLTEAAAQSSDGRAAY Mvan_3833|M.vanbaalenii_PYR-1 QPLGDDAHAYYDQLIEKLEAAPDHVRNIQDMWGDPLTEAAAQSTDGHAAY : *. ** :*: :: * *. ::: *** ** ..:* * ::.: Mb0458c|M.bovis_AF2122/97 VQLSLAGNQGTPLANESVEAVRSIVESTPAPPGIKAYVTGPSALAADMHH Rv0450c|M.tuberculosis_H37Rv VQLSLAGNQGTPLANESVEAVRSIVESTPAPPGIKAYVTGPSALAADMHH MLBr_02378|M.leprae_Br4923 VQLSLAGNQGELLAQESIDAVRKIVVQTPAPPGITAWVTGASALIADMHH MMAR_0094|M.marinum_M VQLNLAGNMGGPLANQSIEAVRQILARTPPPPGIKVYVTGPSALTADMSR MSMEG_0381|M.smegmatis_MC2_155 VQINLHGSFGQAEANESVKAVQDAVESTPAPPGVQAFVTGPAAIVADMGE TH_3056|M.thermoresistible__bu VQVNLVGRFGQAKVNEAVRAVQEIVERTPAPEGVETFVTGPAALGADAGD MAB_4703c|M.abscessus_ATCC_199 VQISLAGNQGQALANKSVEAVRSIVERSAPPPGVQAYVTGPAPLVTDMND MAV_3249|M.avium_104 VQLNLAGNQGTTLGQESVAAVRDVIARIPPPAGLKAYVTGPAALFSDMQL MUL_0757|M.ulcerans_Agy99 VQVKLAGNQGESLANESVEAVKTIVDSLQAPPGVKVYVTGSAALVADQQL Mflv_2705|M.gilvum_PYR-GCK ATLNLAGNMGETESNEAVAAVRDIVANSPPPPGVTVHVTGPAALIADVNI Mvan_3833|M.vanbaalenii_PYR-1 VALNLAGNMGETKSNESVAAVRDIVADSPPPPGVQVHVTGPAALTADVNI . :.* * * :::: **: : .* *: . ***.:.: :* Mb0458c|M.bovis_AF2122/97 SGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVELTAARGVVA Rv0450c|M.tuberculosis_H37Rv SGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVELTAARGVVA MLBr_02378|M.leprae_Br4923 SGDKSMIRITATSVIVILVTLLLVYRSFITVILLLFTVGIESAVARGVVA MMAR_0094|M.marinum_M TGDKSLVIVTMISVLVIFTMLLLVYRSIVTVTLLLITVGIELTAARGVVA MSMEG_0381|M.smegmatis_MC2_155 SGNKTVLLITLVTVGVIFLMLLLLYRRVLIVLILLATVAIELQVARGLVS TH_3056|M.thermoresistible__bu SGTATVILITLVTVAVIFLMLLFFFRSFLTVIVLLLTVAVELQVARGLVA MAB_4703c|M.abscessus_ATCC_199 AGNSSIIKITAVTLVVIFTMLLFVYRSVMTVILLLIMVGIQVQAARGIVA MAV_3249|M.avium_104 AGDRSILKMTLIGALIIFIVLLFVYRSVTTVVLLLLTVGIEVFAARGVIA MUL_0757|M.ulcerans_Agy99 AGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIMLTMVVLGLLATRGGVA Mflv_2705|M.gilvum_PYR-GCK AGERSMALVLLVTFVVIIVLLLFFYRSISTVLLLLVVVGIQLLVARGVVA Mvan_3833|M.vanbaalenii_PYR-1 AGESSMALILLVTFVVIIVLLLFFYRSITTVVLLLIMVGVQMSVARGVVA :* :: : :*: **:.:* . . ::* * : .:** :: Mb0458c|M.bovis_AF2122/97 VLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEARQAGEDKEAA Rv0450c|M.tuberculosis_H37Rv VLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEARQAGEDKEAA MLBr_02378|M.leprae_Br4923 LLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFITGRYQEARQANENKEAA MMAR_0094|M.marinum_M FLAWHGVIGLSTYAINLLTTMAIAAGTDYSIFIIGRYQEARQAGEDAETA MSMEG_0381|M.smegmatis_MC2_155 FLALNGIVGLTTYVVNLLVSVGIAAGTDYGIFFAGRYQEARQAGEDREQA TH_3056|M.thermoresistible__bu YLGLQGWVGLTTYVVNLLVSVGIAAGTDYGIFFFGRYQEAREAGEDRDSA MAB_4703c|M.abscessus_ATCC_199 FLGDQGVIGLSTFSVNLLVSLGIAVGTDYGIFFTGRYQEARQCGEDRETA MAV_3249|M.avium_104 FVANNNLMPLSTFAVNLLVALAMAAGTDYAIFFFGRYQEAREAGEDRATA MUL_0757|M.ulcerans_Agy99 FLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEARGLGQDRESA Mflv_2705|M.gilvum_PYR-GCK ALAHVGVIGLSTYATNLLISLAVAAGTDYAIFLVGRYQEARASGADHEEA Mvan_3833|M.vanbaalenii_PYR-1 ALGHFQVIGLSTFAVNLLISLAVAAGTDYAIFLVGRYQEARASGADPEAA :. : *:*: .** :.:*..***.**: ******* . : * Mb0458c|M.bovis_AF2122/97 YYTMYRGTAHVILGSGLTITGATFCLSFARMPYFQTLGIPCAVGMLVAVA Rv0450c|M.tuberculosis_H37Rv YYTMYRGTAHVILGSGLTIAGATFCLSFARMPYFQTLGIPCAVGMLVAVA MLBr_02378|M.leprae_Br4923 FYTMYRGTFHVILGSGLTISGATFCLSFARMPYFQTLGVPCAVGMLIAVA MMAR_0094|M.marinum_M FYTMYRGVAHVILGSGLTIAGAMYCLTFTRMPYFQSMGIPCAAGMLVAVV MSMEG_0381|M.smegmatis_MC2_155 YYTSFAGVAKVVLASGATIAGAIACLSFTRLPYFQPLGIPGAVGIGVAVA TH_3056|M.thermoresistible__bu YFTTYRSVAKVVLASGLTIAGAIACLSFTRLPHFQPLGIPGAVGLLVAVA MAB_4703c|M.abscessus_ATCC_199 FYTTYSGVAKVVVASGLTIAGAIFCLSFTRLPYFQTMGIPAAIGMAVAVA MAV_3249|M.avium_104 YFTTYRSVAPVVLGSGLTIAGAMLCLSFTRMPIFQTMGLPCSVGMLISVF MUL_0757|M.ulcerans_Agy99 YYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPLAIGMVIVVA Mflv_2705|M.gilvum_PYR-GCK YYEMFHGTAHVVLGSGLTIAGAMLCLSFTRMPYFQSMGIPCAVGIAAGVA Mvan_3833|M.vanbaalenii_PYR-1 YYEMFGGTAHVVLGSGLTIAGAMYCLSFARMPYFQSMGVPCAVGILAGVA :: : .. *::.** **:** **:*:*:* **.:*:* : *: * Mb0458c|M.bovis_AF2122/97 VALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVGTVVVRWPLPVLVATC Rv0450c|M.tuberculosis_H37Rv VALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVGTVVVRWPLPVLVATC MLBr_02378|M.leprae_Br4923 VALTLGPAVLTVGSRFG-LFEPKRLIKVRGWRRIGTVVVRWPLPILITTC MMAR_0094|M.marinum_M AALTMGPAVLALGSRFG-LFDPKRKIKTRGWRRIGTAVVRWPAPILTATC MSMEG_0381|M.smegmatis_MC2_155 VALTLVPACIAATNRFG-WFDPRRLVTTRRWRRIGTAVVRWPAPILIATI TH_3056|M.thermoresistible__bu VALTLVPATIALGSRFG-LFEPKRRVMTHRWRRIGTAVVRWPVPILTAAV MAB_4703c|M.abscessus_ATCC_199 VAVTLVPAVISFGSRFG-LFEPKRRMMVRRWRWIGTATVRWPGPILAAAC MAV_3249|M.avium_104 IALTLVPAVLTVGGGFG-LFDPKRAIGFGRWRRIGTAIVRWPAPILTATI MUL_0757|M.ulcerans_Agy99 TALTLGPALIAVMSRFGKLLEPKRMARVRGWRKIGAAIVRWPGPILIGAV Mflv_2705|M.gilvum_PYR-GCK VALTLGPAIVTVGSRFN-LLEPKRAMRIRAWRRIGTMVVRWPGPILVASL Mvan_3833|M.vanbaalenii_PYR-1 VALTLGPAIVTVGSRFG-LLEPKRAMRIRAWRRVGATVVRWPGPILVASL *:*: ** : . *. ::*:* ** :*: **** *:* : Mb0458c|M.bovis_AF2122/97 AIALVGLLALPGYKTSYNDRDYLPDFIPANQGYAAADRHFSQARMK-PEI Rv0450c|M.tuberculosis_H37Rv AIALVGLLALPGYKTSYNDRDYLPDFIPANQGYAAADRHFSQARMK-PEI MLBr_02378|M.leprae_Br4923 AIAMVGLLALPGYRTNYKDRAYLPASIPANQGFAAADRHFPQARMK-PEI MMAR_0094|M.marinum_M AVSLVGLIALPGYQTNYDDQTYVPENIPANAGYAAANRHFPPSRMK-PDV MSMEG_0381|M.smegmatis_MC2_155 AVAVIGLLTLPGYNPSYSDQKYIPQDIPANQGFAAAARHFPESKMTTPDI TH_3056|M.thermoresistible__bu ALSLVGLLTLPGYNPSYSDQEFIPDDIPASEGYKAAARHFPASAMSVPDV MAB_4703c|M.abscessus_ATCC_199 AVGLVGLLALPGYQTSYDDRLYVPQDIPANVGYAAAQRHFPESRMT-PDV MAV_3249|M.avium_104 AVALVGLVTLPGYKTSYNNRLYMPDSVPANVGYAAADRHFTQSRMM-PEL MUL_0757|M.ulcerans_Agy99 ALALVGLLTLPGYKTNYNDRNYLPADLPANEGYSAAERHFSQARMN-PEV Mflv_2705|M.gilvum_PYR-GCK ALALVGLAALPGYQTSYDDTRYVPESIPANAGLQAATQHFTLSRMS-PEI Mvan_3833|M.vanbaalenii_PYR-1 ALALIGLAALPGYKTSYDDTRYIPESIPANAGLQAATKYFSLSRMS-PEV *:.::** :****...*.: ::* :**. * ** ::*. : * *:: Mb0458c|M.bovis_AF2122/97 LMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAITRPEGTTMDHTSI Rv0450c|M.tuberculosis_H37Rv LMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAITRPEGTTMDHTSI MLBr_02378|M.leprae_Br4923 LMIESDHDMRNPADFLILDKLARGIFRVPGISRVQAITRPDGTAMDHTSI MMAR_0094|M.marinum_M LLIVADHDMRNSADFLVLDKLAKGIFHVPGISRVQAITRPKGTPIEHTSI MSMEG_0381|M.smegmatis_MC2_155 LLVEADHDMRNSADLLVLNKLAKAVFAVPGVSNVQAITRPEGTPIEHTSI TH_3056|M.thermoresistible__bu VLIEADRDMRNPADLLVLNKVAKKIFEVPGVANVQSVTRPEGRQIEHTTI MAB_4703c|M.abscessus_ATCC_199 MLLEADHDMRNPADFVVLHKLAKGLFAVPGISMVQSITRPEGSPIERTSI MAV_3249|M.avium_104 LMIESDHDMRNPADFLVLHRLAKGVFGVHGISRVQGITRPEGTPIQHTSI MUL_0757|M.ulcerans_Agy99 LMVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQAITRPDGKPIEHTSI Mflv_2705|M.gilvum_PYR-GCK LIVEADRDLRNPADFLVLDRLAKRVFAVEGVARVQAPSRPDGSPIAKTSI Mvan_3833|M.vanbaalenii_PYR-1 LIVEADRDLRNSSDFLILDRLAKRVFNVEGVARVQAPSRPDGAPIAHTSI ::: :*:*:**.:*::::.::*: :* * *:: **. :**.* : :*:* Mb0458c|M.bovis_AF2122/97 PFQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTRMHSLMAEMA Rv0450c|M.tuberculosis_H37Rv PFQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTRMHSLMAEMA MLBr_02378|M.leprae_Br4923 PFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAETIASMRRMHQLMALLT MMAR_0094|M.marinum_M PFQISMQNAGQLQNMKYQRDRMNDMLTQADQLTSTIALMKRTYDLMLQMS MSMEG_0381|M.smegmatis_MC2_155 PFMLSMSNASQRLSLPFQQQRMEDLLKQADELTKNIALMKHMYALMQEMV TH_3056|M.thermoresistible__bu PFMLSMSQASQRLALPFQRARMDDMLKQADELTETIALMRRMQSLMEKMV MAB_4703c|M.abscessus_ATCC_199 PFQISLQSAGMLQILPFGKERVDDMLKQAEDTTKMINQMQHTYELMSNIS MAV_3249|M.avium_104 PFLLSMQQATMHQDIQYMKARMDDMLVQADLMRKQIEIMRHIYELQKRLT MUL_0757|M.ulcerans_Agy99 PFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNIDQMERMHDLTQQMA Mflv_2705|M.gilvum_PYR-GCK PFLISMQGVGQQQNMKLMQDRMDDMRTQADNLGKTLGTMRTMYGLMTRLS Mvan_3833|M.vanbaalenii_PYR-1 PFLISMQGVGQQQNMKLMKDRIADMRVQADDIGETIATMKTMYGLMTKFS ** :*:. . : .: *.: : : * : Mb0458c|M.bovis_AF2122/97 STTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWEKHCYGIPIC Rv0450c|M.tuberculosis_H37Rv STTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWEKHCYGIPIC MLBr_02378|M.leprae_Br4923 ENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPIRSYFYWERHCFNIPIC MMAR_0094|M.marinum_M KTTHRMVGDTLEMKSVTDELRDHIADFEDTWRPIRSYFYWEKHCADIPIC MSMEG_0381|M.smegmatis_MC2_155 ATTHSTVETTHEVQQTTKDLRDSIEDFQDFWRPIRNYLYWEPHCYDIPLC TH_3056|M.thermoresistible__bu ATTHSMVGTTHELLDTTRDLRDHIADFDDFFRPIRNYFHWEPHCYNIPIC MAB_4703c|M.abscessus_ATCC_199 GITNETVVMNRELTATVDRLRDYIANFDDFFKPLRNYLYWEKHCETIPIC MAV_3249|M.avium_104 DITHDSIVKTKEMAAVLWELRDKMSDFEDFWRPLRSYFYWEKHCYDIPIC MUL_0757|M.ulcerans_Agy99 DVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRSYFYWEKHCFDIPVC Mflv_2705|M.gilvum_PYR-GCK EVTTVMIDDFTEMQQTVHQIRDMVANFDDQFRPVRNYFYWEPHCYNIPLC Mvan_3833|M.vanbaalenii_PYR-1 NITTVMIDDMTEMRDTVHQIRDMVATFDDQFRPIRNYFYWEPHCYNIPLC * : : :*: : *:* ::*:*.*::** ** **:* Mb0458c|M.bovis_AF2122/97 WSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQIPPQIEAMEN Rv0450c|M.tuberculosis_H37Rv WSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQIPPQIEAMEN MLBr_02378|M.leprae_Br4923 WSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMPQMLEQFPPMIESMES MMAR_0094|M.marinum_M WSLRSIFDALDGVDQVSEQLTTLTGDLTDMDRILPQVVATFPQMIQNMEG MSMEG_0381|M.smegmatis_MC2_155 WSIRSLFDGLDGINEVTDKMGDLVEDLDHLDTLMPQMLLQFPPMIAMLEN TH_3056|M.thermoresistible__bu WSIRSIFDALDGINEMTEKMEELVEDMDRLDALMPQMLVQFPQMIETMES MAB_4703c|M.abscessus_ATCC_199 FAIRSVFQALDGTDLLSERTHRILERVEEMNLYQRELIALFPPMITTMKS MAV_3249|M.avium_104 WSLRNIFETLDGVDTLSDKMTYLLQDLDHMDRLMPQLLEQYPPMIAMSED MUL_0757|M.ulcerans_Agy99 WSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQMTAMMPEMIQTMKS Mflv_2705|M.gilvum_PYR-GCK WSFRSLFDSMDGISTMTESFDKALVNMETMRSLLPQMLATFPPMIETMES Mvan_3833|M.vanbaalenii_PYR-1 WSFRSLFDSMDGISVMTDTFDKAVANMDEMKALLPQMLATFPPMIETMES :::*.:*: :** . : : : : :: * * :. Mb0458c|M.bovis_AF2122/97 MRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAAKNDDSFYLPPEVFK Rv0450c|M.tuberculosis_H37Rv MRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAAKNDDSFYLPPEVFK MLBr_02378|M.leprae_Br4923 MRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFDTAKNDDSFYLPPEVFK MMAR_0094|M.marinum_M MRTLILTMHSTMSGIYDQMDELSKNSTAMGQAFDAAKNDDSFYLPPEVFN MSMEG_0381|M.smegmatis_MC2_155 SRSMILTMHSTMSGIFSQMDDSTDNATAMGKAFDAARNDDSFYLPPDILE TH_3056|M.thermoresistible__bu SRTMILTMHATMSGIFDQMESSSENATAMGKAFDASHNDDSFYLPPEALE MAB_4703c|M.abscessus_ATCC_199 MRAMMLTMHSTMSGIFSLIDQTAANASAMGKIYDGAQNDDSFYLPPEVFE MAV_3249|M.avium_104 MLRMMLTNHSTMSGIIGQMDSNNKDATAMGEAFDASKNDDSFYLPPDIFD MUL_0757|M.ulcerans_Agy99 MKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDSSRNDDSFYLPPEVFN Mflv_2705|M.gilvum_PYR-GCK MRQMMLTTYATMGGFYDQMDELTQDSTEMGKAFDEAKNDDSFYLPPEVFE Mvan_3833|M.vanbaalenii_PYR-1 MRQMMLTTYATMGGFYDQMDELTRDSTEMGKAFDAAKNDDSFYLPPEVFE :*: ::* *: . : ::. **: :* ::*********: :. Mb0458c|M.bovis_AF2122/97 NKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGIKSIDAIRTAAEESLK Rv0450c|M.tuberculosis_H37Rv NKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGIKSIDAIRTAAEESLK MLBr_02378|M.leprae_Br4923 NTDFKRAMKSFLSSDGHAARFIILHRGDPASVAGIASINAIRTAAEEALK MMAR_0094|M.marinum_M NPDFKRGMKMFLSQDGKAARLFIFHRGNAAGYEGISSISAINIAAAEALK MSMEG_0381|M.smegmatis_MC2_155 NEDFKRVMKIFMSPDGKAARMLITQRGDPATPEGIALVEPIRVAAEEALK TH_3056|M.thermoresistible__bu NKDFQRVMEIFLSPDGKAARMLVTQRGDPATPEGMALVEPIYIAAEEALK MAB_4703c|M.abscessus_ATCC_199 NEDFKRAMSLFFSPDGKAVRLILTYRGDPGTPDSLSRVNAVRLAAQEALK MAV_3249|M.avium_104 NADFKKAMSQFLSPDGKAARFIISHRGDPATSEALNRIDKIRSAAEEALK MUL_0757|M.ulcerans_Agy99 NPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAGINHIDKIKTAAKEAIK Mflv_2705|M.gilvum_PYR-GCK NEDFKRAMESFFSPDGKTVRMLVSHRGDPTTPEALARVEPIKIAAIEALK Mvan_3833|M.vanbaalenii_PYR-1 NEDFKRAMESFFSPDGKTVRMLIAHRGNPTTDEALQRVEPIKIAAIEALK * **:: :. *:* **::.*::: .*:. .: :. : ** *::* Mb0458c|M.bovis_AF2122/97 GTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLCLIFIIMLIITRA Rv0450c|M.tuberculosis_H37Rv GTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLCLIFIIMLIITRA MLBr_02378|M.leprae_Br4923 GTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGISSLCLIFIIMLIITRA MMAR_0094|M.marinum_M GTPLEDAQIYLTGTAAVYKDIADGSKYDLIIAGLSSLCLIFIIMLLITRG MSMEG_0381|M.smegmatis_MC2_155 GTPLESAELHLAGTAAGVKDLVDGSKIDLLIAGVAALCLIFIIMLIMTRS TH_3056|M.thermoresistible__bu GTPLESSRIYLAGSAAGVKDLVEGAKYDLMIAAISAVCLIFMIMVFMTRS MAB_4703c|M.abscessus_ATCC_199 VTPLENATIHLAGTAATFKDLRDGSAYDLLIAGVAALCLIFGIMLIMTRS MAV_3249|M.avium_104 NTPLENAKIYLAGTASTFKDFRDGSTYDLFIAGVGALCLIFIIMLILTRS MUL_0757|M.ulcerans_Agy99 GTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGISALCLIFIIMLIITRS Mflv_2705|M.gilvum_PYR-GCK GTPLENAQIQLGGTAATFKDMSDGSRYDMMIAILSALCLVLVIMLVLTRS Mvan_3833|M.vanbaalenii_PYR-1 GTPLENAQIQLGGTAATFKDMSDGSRYDLLIAVISALCLVLMIMLVLTRS ****.: : * *:.: :*: :* *:.** :.::**:: **:.:**. Mb0458c|M.bovis_AF2122/97 FIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLAMSVIVLLAVG Rv0450c|M.tuberculosis_H37Rv FIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLAMSVIVLLAVG MLBr_02378|M.leprae_Br4923 FVAAAVIVGTVALSLGASFGLSVLLWQHILGIELHYLVLAMSVIVLLAVG MMAR_0094|M.marinum_M FVAALVIVGTVALSLGVSFGLSVLLWQHLLRIELHWLVLAMSVIVLLAVG MSMEG_0381|M.smegmatis_MC2_155 FIAALVIVGTVAMSLGASFGLSVLVWQHLLGIQINWVVLAMSVIVLLAVG TH_3056|M.thermoresistible__bu VIAALVIVGTVVLSLGASFGMSVLLWQHLLGIQLHWVVLAMSVIVLLAVG MAB_4703c|M.abscessus_ATCC_199 FVAALVIVGTVALSLGAAFGLSVLIWQNILGIELHWLVLAMSVIILLAVG MAV_3249|M.avium_104 FIAALVIVGTVTLSLGASFGLSVLIWQYIFGIQLYWMVLPMSVIVLLAVG MUL_0757|M.ulcerans_Agy99 VVAAAVIVGTVVLSLGASFGLSVLIWQHVLGIELHWLVLAMAVIILLAVG Mflv_2705|M.gilvum_PYR-GCK LVAAVVIVGTVALSLGASFGVSVLIWQHLLGVELHWMVLVMSIIALIAVG Mvan_3833|M.vanbaalenii_PYR-1 LVAALVIVGTVTLSLGASFGISILIWQHIVGIELHWMVLALSIIALIAVG .:** ******.:***.:**:*:*:** :. :.: ::** :::* *:*** Mb0458c|M.bovis_AF2122/97 SDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTNAGLVFAVTMASMAV Rv0450c|M.tuberculosis_H37Rv SDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTNAGLVFAVTMASMAV MLBr_02378|M.leprae_Br4923 SDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVVTNAGLVFAFTMASMVV MMAR_0094|M.marinum_M SDYNLLLVSRLKEEVGAGIKTGIIRAMGGTGKVVTSAGLVFALTMASMAV MSMEG_0381|M.smegmatis_MC2_155 SDYNLLLVSRMKEEIGAGLNTGIIRAMGGTGKVVTAAGLVFAATMASMIV TH_3056|M.thermoresistible__bu SDYNLMLVSRMKEEIGAGLNTGIIRAMGGTGRVVTMAGLVFAATMASMIV MAB_4703c|M.abscessus_ATCC_199 SDYNLLLVSRMKEELGAGINTGIIRAMGGTGKVVTSAGLVFAFTMLSMVV MAV_3249|M.avium_104 SDYNLLLVSRMKEEISAGINTGIIRAMGGTGKVVTNAGLVFAFTMASMVV MUL_0757|M.ulcerans_Agy99 ADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAGLVFAFTMMSFAV Mflv_2705|M.gilvum_PYR-GCK SDYNLLLVSRFKEEIGAGIKTGIIRAIGGTGSVVSVAGVVFALTMASMVV Mvan_3833|M.vanbaalenii_PYR-1 SDYNLLLVSRFKEEIPAGIKTGIIRAIGGTGSVVTVAGVVFALTMASMVV :****:**:*:*:*: **::*****::**:* **: **:*** ** *: * Mb0458c|M.bovis_AF2122/97 SDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFWWPLRVRSRP Rv0450c|M.tuberculosis_H37Rv SDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFWWPLRVRSRP MLBr_02378|M.leprae_Br4923 SDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAALLGRWFWWPQQGRTRP MMAR_0094|M.marinum_M SDLIVIGQIGTTIGLGLLFDTLIVRSLMTPSIAALLGRWFWWPLNIRSRP MSMEG_0381|M.smegmatis_MC2_155 SDLLTIGQVGTTIGLGLLFDTLVVRAFMTPSIAALLGRWFWWPQRVRQRP TH_3056|M.thermoresistible__bu SDLLMIGQVGTTIALGLLFDTMVVRAFMTPSVAAILGRWFWWPQRVRTRP MAB_4703c|M.abscessus_ATCC_199 SDLRVIGQVGSTIGIGLLFDTLVVRAFMTPAIAALLGRWFWWPQRIRRRP MAV_3249|M.avium_104 SDLRIIGQVGTTIGLGLMFDTLIVRSFMTPTIAALLGRWFWWPQLVRRRP MUL_0757|M.ulcerans_Agy99 SELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGKWFWWPQVVRQRP Mflv_2705|M.gilvum_PYR-GCK SDLKVIAQVGTTIGLGLLFDTFIVRAFMMPSIATLLGRWFWWPLVVRSRP Mvan_3833|M.vanbaalenii_PYR-1 SDLRVMAQVGTTIGLGLLFDTFIVRAFMMPAIATLLGRWFWWPLVVRSRP *:* :.*:*:**.:**:***::**::* *::*::**:***** * ** Mb0458c|M.bovis_AF2122/97 ARTPTVPSETQPAGRPLAMSSDRLG------------- Rv0450c|M.tuberculosis_H37Rv ARTPTVPSETQPAGRPLAMSSDRLG------------- MLBr_02378|M.leprae_Br4923 LLTVAAPVGLPPD-RSLVYSD----------------- MMAR_0094|M.marinum_M PRLTRQRPLPSVSQEPAAARV----------------- MSMEG_0381|M.smegmatis_MC2_155 ASAMLRSVGPRPLVRSLLLRD----------------- TH_3056|M.thermoresistible__bu ASAMLRPVGPRPLVRSLLLRD----------------- MAB_4703c|M.abscessus_ATCC_199 AITSQAPAERR--MRVLLDA------------------ MAV_3249|M.avium_104 ASQLLRSEGTRRSVRVLLHQNDDADADTAEIPVPRPTA MUL_0757|M.ulcerans_Agy99 APQPWPTPAPTPPPATTSV------------------- Mflv_2705|M.gilvum_PYR-GCK LRPRPQQQALGVGGQQG--------------------- Mvan_3833|M.vanbaalenii_PYR-1 LRLPPRT-------------------------------