For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MPRVTDDHLAARRRQILDGARRCFAEYGYESATVRRLEQTIGLSRGAIFHHFRDKDTLFFELAREDAERM ADVAAREGLIQVMRDMLAAPDQFDWLATRLEIARKLRNDPAFSQGWAERSAELSAATTERLRRQKQAGRL RDDVDGEVLRTYLELVLDGLVARLASGDDPEKLSAVLDLVEASVRQP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3666 | - | - | 100% (187) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4158 | - | 2e-06 | 25.17% (147) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3637 | - | 2e-06 | 32.47% (77) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1510c | - | 3e-86 | 82.80% (186) | transcriptional regulatory protein |
| M. tuberculosis H37Rv | Rv1474c | - | 3e-86 | 82.80% (186) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2731 | - | 1e-80 | 78.49% (186) | TetR family transcriptional regulator |
| M. marinum M | MMAR_2281 | - | 5e-87 | 83.33% (186) | transcriptional regulatory protein |
| M. avium 104 | MAV_3305 | - | 2e-87 | 83.87% (186) | HTH-type transcriptional repressor AcnR |
| M. smegmatis MC2 155 | MSMEG_3142 | - | 4e-90 | 87.63% (186) | HTH-type transcriptional repressor AcnR |
| M. thermoresistible (build 8) | TH_0251 | - | 2e-90 | 89.56% (182) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_1483 | - | 1e-86 | 82.80% (186) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_2744 | - | 5e-98 | 95.70% (186) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1510c|M.bovis_AF2122/97 MPKVSEDHLAARRRQILDGARRCFAEYGYDKATVRRLEQAIGMSRGAIFH
Rv1474c|M.tuberculosis_H37Rv MPKVSEDHLAARRRQILDGARRCFAEYGYDKATVRRLEQAIGMSRGAIFH
MMAR_2281|M.marinum_M MPKVSEDHLAARRRQILDGARRCFAEYGYDKATVRRLEQAIGMSRGAIFH
MUL_1483|M.ulcerans_Agy99 MPKVSEDHLAARRRQILDGARRCFAEYGYDKATVRRLEQAIGMSRGAIFH
MAV_3305|M.avium_104 MPKVSEDHLAARRRQILDGARRCFAEFGYDKATVRRLEQAIGMSRGAIFH
Mflv_3666|M.gilvum_PYR-GCK MPRVTDDHLAARRRQILDGARRCFAEYGYESATVRRLEQTIGLSRGAIFH
Mvan_2744|M.vanbaalenii_PYR-1 MPRVTDDHLAARRRQILDGARRCFAEYGYDRATVRRLEQTIGLSRGAIFH
MSMEG_3142|M.smegmatis_MC2_155 MPRVTDDHLAARRRQILDGARRCFAKYGYESATVRRLEETIGLSRGAIFH
TH_0251|M.thermoresistible__bu ---VTDDHLAARRRQILDGARRCFAEYGYEQATVRRLEQATGLSRGAIFH
MAB_2731|M.abscessus_ATCC_1997 MPRVSEDHLAARRRQILDGARRCFAEYGYDGATVRRLEHTIGMSRGAIFH
*::*******************::**: *******.: *:*******
Mb1510c|M.bovis_AF2122/97 HFRDKDALFFALAREDTERMAAVASREGLIGVMRDMLAAPDQFDWLATRL
Rv1474c|M.tuberculosis_H37Rv HFRDKDALFFALAREDTERMAAVASREGLIGVMRDMLAAPDQFDWLATRL
MMAR_2281|M.marinum_M HFRDKDALFFALAHEDAERMADVASREGLIQVMRDMLAAPDQFDWLATRL
MUL_1483|M.ulcerans_Agy99 HFRDKDALFFALAHEDAERMADVASREGLIQVMRDMLAAPEQFDWLATRL
MAV_3305|M.avium_104 HFRDKDALFFALAHEDAERMAEVASRAGLIQVMRDMLAAPDQFDWLATRL
Mflv_3666|M.gilvum_PYR-GCK HFRDKDTLFFELAREDAERMADVAAREGLIQVMRDMLAAPDQFDWLATRL
Mvan_2744|M.vanbaalenii_PYR-1 HFRDKDTLFFELAREDAERMADVAAREGLIQVMRDMLAAPDQFNWLATRL
MSMEG_3142|M.smegmatis_MC2_155 HFKDKDTLFFELAREDAERMAEVAAREGLIQVMRDLLAAPEQYDWLATRL
TH_0251|M.thermoresistible__bu HFKDKDTLFFELAREDAERMAEVASREGLIQVMRDLIAAPEQYDWLTTRL
MAB_2731|M.abscessus_ATCC_1997 HFRDKDTLFFALAREDAERMANVASREGLVQVMRDMLADPSQFDWLATRL
**:***:*** **:**:**** **:* **: ****::* *.*::**:***
Mb1510c|M.bovis_AF2122/97 EIARKLRNDPDFSRGWAERSAELAAATTDRLRRQKQANRVRDDVPSDVLR
Rv1474c|M.tuberculosis_H37Rv EIARKLRNDPDFSRGWAERSAELAAATTDRLRRQKQANRVRDDVPSDVLR
MMAR_2281|M.marinum_M EIARKLRNDPEFSRGWAERSAELAAATTDRLRRQKQANRVRDDVPNEVLQ
MUL_1483|M.ulcerans_Agy99 EIARKLRNDPEFSRGWAERSAELAAATTDRLRRQKQANRVRDDVPNEVLQ
MAV_3305|M.avium_104 EIARKLRNDPAFSRGWAERSAELAAATTDRLRRQTEAHRVRDDVPGDVLQ
Mflv_3666|M.gilvum_PYR-GCK EIARKLRNDPAFSQGWAERSAELSAATTERLRRQKQAGRLRDDVDGEVLR
Mvan_2744|M.vanbaalenii_PYR-1 EIARKLRNDPAFSRGWAERSAELSAATTERLRRQKRAGRLRDDVPGDVLR
MSMEG_3142|M.smegmatis_MC2_155 EIARKLRNDPDFHRGWAERSAELTAATTERLRRQKQAGRLRDDVPSAVLH
TH_0251|M.thermoresistible__bu EIARKLRNDPEFHRGWSELSAELAAATTARLRRQKQAGRLRDDVPGEVLR
MAB_2731|M.abscessus_ATCC_1997 EIARKLRNDPEFRRGWNQRSEELNTATLARLQRQKKAGRLREDVPSEVIL
********** * :** : * ** :** **:**..* *:*:** . *:
Mb1510c|M.bovis_AF2122/97 CYLDLVLDGLLARLASGEDPQRLAAVLDLVENSVRRS-------------
Rv1474c|M.tuberculosis_H37Rv CYLDLVLDGLLARLASGEDPQRLAAVLDLVENSVRRS-------------
MMAR_2281|M.marinum_M CYLDLVLDGLVARLASGEDPQRLTDVLDLVENSLRRS-------------
MUL_1483|M.ulcerans_Agy99 CYLDLVLDGLVARLASGEDPQRLTDVLDLVENSLRRS-------------
MAV_3305|M.avium_104 CYLELVLDGLVARLASGEDPQRLSAVLDLVENSVRRNDSRPG--------
Mflv_3666|M.gilvum_PYR-GCK TYLELVLDGLVARLASGDDPEKLSAVLDLVEASVRQP-------------
Mvan_2744|M.vanbaalenii_PYR-1 TYLELVLDGLVARLASGDDPEKLGAVLDLVEASVRQQ-------------
MSMEG_3142|M.smegmatis_MC2_155 IYLDVVLDGLVARLASGEDSKNLSAVLDLVEASVRQQPKPAPAVSTDHSF
TH_0251|M.thermoresistible__bu TYLELVLDGLVARLASGDDPEKLSAVLDLVEASVRHQGSE----------
MAB_2731|M.abscessus_ATCC_1997 GYLDLVLDGLVARLAAGESTESLSRVLDLVEDSVRRADHA----------
**::*****:****:*:..: * ****** *:*:
Mb1510c|M.bovis_AF2122/97 ----
Rv1474c|M.tuberculosis_H37Rv ----
MMAR_2281|M.marinum_M ----
MUL_1483|M.ulcerans_Agy99 ----
MAV_3305|M.avium_104 ----
Mflv_3666|M.gilvum_PYR-GCK ----
Mvan_2744|M.vanbaalenii_PYR-1 ----
MSMEG_3142|M.smegmatis_MC2_155 SDES
TH_0251|M.thermoresistible__bu ----
MAB_2731|M.abscessus_ATCC_1997 ----