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TSTDQGSWARSEGDSWDIVSSVGYTALGVSAQRAVESERPDALIDDPFAKHFVLAAGEPHLIETITKRDA PQASPFEYLRGMGMRSRFFDEFFLEAAASGITQAVILAAGLDARAHRLAWPAGVTVYELDQPQVLAFKDG VYAQQGAEPTCDRRTVAVDLRDDWPAALKEAGFDAGRPTAWSAEGLLPYLPAAAQELLFERMVELSAPGS RAAIEGPTGTLGMSQFAKVEQKYRSEKDTFGKIDITELFYDEEKTPPVEWFSVRGWSTQGLDMFDLAERY GVRHPEVPEDIRELAGAMHYLTCTLPA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4585c | - | - | 100% (308) | hypothetical protein MAB_4585c |
| M. abscessus ATCC 19977 | MAB_4584c | - | e-101 | 57.47% (308) | hypothetical protein MAB_4584c |
| M. abscessus ATCC 19977 | MAB_4586c | - | 7e-70 | 49.82% (273) | hypothetical protein MAB_4586c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3793c | - | 2e-61 | 44.44% (297) | hypothetical protein Mb3793c |
| M. gilvum PYR-GCK | Mflv_5024 | - | 5e-63 | 44.16% (308) | putative methyltransferase |
| M. tuberculosis H37Rv | Rv3767c | - | 2e-61 | 44.44% (297) | hypothetical protein Rv3767c |
| M. leprae Br4923 | MLBr_02020 | - | 1e-63 | 44.16% (308) | hypothetical protein MLBr_02020 |
| M. marinum M | MMAR_2791 | - | 3e-65 | 45.51% (312) | hypothetical protein MMAR_2791 |
| M. avium 104 | MAV_4442 | - | 4e-67 | 45.75% (306) | methyltransferase, putative, family protein |
| M. smegmatis MC2 155 | MSMEG_1480 | - | 4e-66 | 45.33% (300) | methyltransferase |
| M. thermoresistible (build 8) | TH_2706 | - | 6e-64 | 46.58% (292) | PUTATIVE putative methyltransferase |
| M. ulcerans Agy99 | MUL_2961 | - | 5e-64 | 45.51% (312) | hypothetical protein MUL_2961 |
| M. vanbaalenii PYR-1 | Mvan_0104 | - | 8e-65 | 46.45% (282) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5024|M.gilvum_PYR-GCK -MA--------RTDGDTWDLASSVGATATSVAASRAFASRGPDALIDDPY
MSMEG_1480|M.smegmatis_MC2_155 -MT--------RTDGDTWDLATSVGSTATGVAAMRALATRQPDPLIDDPY
MAV_4442|M.avium_104 -MSEG------RTDGDTWGPAQSVGATATMVAAARAVASQGPDALLDDPL
TH_2706|M.thermoresistible__bu -MA--------RSESDTWDLTSGVGVTATMVAAARALASREPEPLIDDPF
Mb3793c|M.bovis_AF2122/97 -MP--------RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPF
Rv3767c|M.tuberculosis_H37Rv -MP--------RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPF
Mvan_0104|M.vanbaalenii_PYR-1 -MSSL------RTDNDTWDIASSVGATAVMVAAARAAETERPEPLIDDPY
MAB_4585c|M.abscessus_ATCC_199 -MTSTDQGSWARSEGDSWDIVSSVGYTALGVSAQRAVESERPDALIDDPF
MMAR_2791|M.marinum_M --MTTSEYGSRRSDDDQWDIVSGVGYTALLVAGWRALDTVGPQPLAPDEY
MUL_2961|M.ulcerans_Agy99 --MTTSEYGSRRSDDDQWDIVSGVGYTALLVAGWRALDTVGPQPLAPDEY
MLBr_02020|M.leprae_Br4923 MMAATPEFGSLRSDDDHWDIVSSVGYTALLVAGWRALHAVGPQPLVRDEY
*::.* * . .** ** *:. ** : :.* *
Mflv_5024|M.gilvum_PYR-GCK ARLLVEAVGLPHFVKVARG---EIDFDGDPLFG---AQQAINQIVVRTRI
MSMEG_1480|M.smegmatis_MC2_155 ADALVKAVGLEHCIALADG---ETCVEGDPMLD---LNRMCEQIAVRTRY
MAV_4442|M.avium_104 AEPLVRAVGLDPFIRIVDG---KLDFPDDPLFN---RRARAEQITVRTRF
TH_2706|M.thermoresistible__bu AAPLVRAVGVEFFTRLVDG---DLELPADTAEERAAAQVLTEVMAVRTRF
Mb3793c|M.bovis_AF2122/97 ARIFVDAAGDGIWSMYTNRTLLAGATDLDPDLR-APIQQMIDFMAARTAF
Rv3767c|M.tuberculosis_H37Rv ARIFVDAAGDGIWSMYTNRTLLAGATDLDPDLR-APIQQMIDFMAARTAF
Mvan_0104|M.vanbaalenii_PYR-1 AKILVAGAGNGAWQYIADDGFVAKVTESDPEIG-PLFEHMKNYQAVRTHF
MAB_4585c|M.abscessus_ATCC_199 AKHFVLAAGEPHLIETITK-------RDAPQAS---PFEYLRGMGMRSRF
MMAR_2791|M.marinum_M AKYFIAASGDAYLNDQLAH--------PPTSVD---ETAFPRLYGVQTRF
MUL_2961|M.ulcerans_Agy99 AKYFIAASGDAYLNDQLAH--------PPTSVD---ETAFPRLYGVQTRF
MLBr_02020|M.leprae_Br4923 AKYFITASRDPYLMNLLAN--------PGTSLN---ETAFPRLYGVQTRF
* :: . . ::
Mflv_5024|M.gilvum_PYR-GCK FDDFLTDAGQREPQIRQAVILASGLDTRAYRLDWPAGTVVYEIDQPEVID
MSMEG_1480|M.smegmatis_MC2_155 FDELFIAAG--ADGVRQAVILASGLDTRAYRLDWPAGTVVFEVDQPQVIE
MAV_4442|M.avium_104 FDDFFIDAT--EGGLRQAVILASGLDTRAYRLAWPAGTVVYEIDQPQVIA
TH_2706|M.thermoresistible__bu FDDFFTDAT--RVGARQAVILASGLDARAYRLTWPDGTVVYEIDQPEVIA
Mb3793c|M.bovis_AF2122/97 FDEYFLATA--DAGVRQVVILASGLDSRAWRLPWPDGTVVYELDQPKVLE
Rv3767c|M.tuberculosis_H37Rv FDEYFLATA--DAGVRQVVILASGLDSRAWRLPWPDGTVVYELDQPKVLE
Mvan_0104|M.vanbaalenii_PYR-1 FDAFFAAAV--DAGIRQIVILASGLDSRAFRLPWPAGTTVFEIDQPLVLA
MAB_4585c|M.abscessus_ATCC_199 FDEFFLEAA--ASGITQAVILAAGLDARAHRLAWPAGVTVYELDQPQVLA
MMAR_2791|M.marinum_M FDDFFRSAA--AAGTKQAVIVAAGLDSRAYRLEWPSGTTVFEIDLPQVLE
MUL_2961|M.ulcerans_Agy99 FDDFFR-SA--AAGTKQAVIVAAGLDSRAYRLEWPSGTTVFEIDLAQVLE
MLBr_02020|M.leprae_Br4923 FDDFFSSAG--DTGIRQAVIVAAGLDSRAYRLKWPNGATVFEIDLPKVLE
** : : * **:*:***:** ** ** *..*:*:* . *:
Mflv_5024|M.gilvum_PYR-GCK FKTAVLTDAGVAPAADRRTVGIDLREDWPTALRDAGFDPDRPTAWIAEGL
MSMEG_1480|M.smegmatis_MC2_155 FKTRTLADLGAQPTAERRTVAVDLRDDWPAALRDAGFDPAEPTAWIAEGL
MAV_4442|M.avium_104 FKTDTLANLGAAPTAERRTISIDLRDDWPAALREGGFDVTRPTAWSAEGL
TH_2706|M.thermoresistible__bu FKTRTLAELGAPPTAPHRPVAVDLRDDWPAALTAAGFDPTVATAWSAEGL
Mb3793c|M.bovis_AF2122/97 FKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCAWLAEGL
Rv3767c|M.tuberculosis_H37Rv FKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCAWLAEGL
Mvan_0104|M.vanbaalenii_PYR-1 YKSSTLASHGVQPTADRREVPIDLRQDWPTALTHAGFDADQPTAWLAEGL
MAB_4585c|M.abscessus_ATCC_199 FKDGVYAQQGAEPTCDRRTVAVDLRDDWPAALKEAGFDAGRPTAWSAEGL
MMAR_2791|M.marinum_M FKARVLQRHGVEPKARRNEVAADLRTDWPATLHAAGFEPGQPSAWSVEGL
MUL_2961|M.ulcerans_Agy99 FKARVLQRHGVEPKARRNAVAADLRTDWPATLHAAGFEPGQPSAWSVEGL
MLBr_02020|M.leprae_Br4923 FKARVLAEQGAIPNAGRSEVAADLRADWPRALKAAGFDPQRSSAWSVEGL
:* . *. * . : *** *** :* .**: . ** .***
Mflv_5024|M.gilvum_PYR-GCK LPYLPPDAQDRLLDSITALSAPGSRLATEHM-DAKALTGDWAKAMTERAR
MSMEG_1480|M.smegmatis_MC2_155 LIYLPAEAQDRLLDNITALSAPGSRLATEHM-DHRILAEGAGKRIGEWSR
MAV_4442|M.avium_104 LPYLPPEAQDRLFDNITALSAPGSRLATEHVPDPNAFSDERLARISERWQ
TH_2706|M.thermoresistible__bu LRYLPPDAQDRLFDHITDLSAPGSRLATEDHPGPGAGLGEKADELGRRWR
Mb3793c|M.bovis_AF2122/97 VRYLPARAQDLLFERIDALSRPGSWLASNVP-GAGFLDPERMRRQRADMR
Rv3767c|M.tuberculosis_H37Rv VRYLPARAQDLLFERIDALSRPGSWLASNVP-GAGFLDPERMRRQRADMR
Mvan_0104|M.vanbaalenii_PYR-1 LMYLPADAQDRLFAQITELSAPGSRVAAESM-GIHAQD----RRER--MR
MAB_4585c|M.abscessus_ATCC_199 LPYLPAAAQELLFERMVELSAPGSRAAIEGPTGTLGMSQFAKVEQKYRSE
MMAR_2791|M.marinum_M LPYLTADAQDALFARIDDLCAPGSRIATGALGSRLDHDQLVALEQTHPGV
MUL_2961|M.ulcerans_Agy99 LPYLTADAQDALFARIDDLCAPGSRIATGALGSRLDHDQLVALEQTHPGV
MLBr_02020|M.leprae_Br4923 LPYLTNDAQSALFTRIGELCAPGSRIAVGALGSRLDRKQLAALEATHPGV
: **. **. *: : *. *** * .
Mflv_5024|M.gilvum_PYR-GCK RHGSD---------IDLTKLFYNGE-RRSATEHLGAVGWQTS-VQTSNDA
MSMEG_1480|M.smegmatis_MC2_155 RVGSS---------LDIADLFYTGE-RNTAGDYLRGLGWQVT-VRPSKEA
MAV_4442|M.avium_104 RLGLN---------LNAADLFYRGE-RNVVADYLTGKGWRVT-PHPARQL
TH_2706|M.thermoresistible__bu EHGFE---------VQLSELFHPGE-RTPVVDYLRGRGWDAR-ARPRAEV
Mb3793c|M.bovis_AF2122/97 RMRAAAAKLVETEISDVDDLWYAEQ-RTAVAEWLRERGWDVS-TATLPEL
Rv3767c|M.tuberculosis_H37Rv RMRAAAAKLVETEISDVDDLWYAEQ-RTAVAEWLRERGWDVS-TATLPEL
Mvan_0104|M.vanbaalenii_PYR-1 ERFASITAQFDVEPMDITELTYEDPDRADVAQWLTAHGWRAE-AVPSQDE
MAB_4585c|M.abscessus_ATCC_199 KDTFG--------KIDITELFYDEE-KTPPVEWFSVRGWSTQ-GLDMFDL
MMAR_2791|M.marinum_M NLSGD---------VNFSALTYDDK--TNPAQWLAARGWVVEPVRNTLEL
MUL_2961|M.ulcerans_Agy99 NLFGD---------VNFSALTYDDK--TNPAQWLAARGWVVEPVRNTLEL
MLBr_02020|M.leprae_Br4923 NISGD---------VDFSALTYEPK--TDSAQWLAAHGWAVEPVRNTLEL
. : * : : : ** . :
Mflv_5024|M.gilvum_PYR-GCK YIANGFG--PIRDDLLAMIGDSGYLTAWRP-------
MSMEG_1480|M.smegmatis_MC2_155 YADHGF---ELPEEMAELSGDSGYLSAHLK-------
MAV_4442|M.avium_104 YARNGFE--FPEDEMRATFGEMSYVDATLTGGRG---
TH_2706|M.thermoresistible__bu FAGYGRE--FPDSAALAAMRDSSAVTAVRPVVRAGMR
Mb3793c|M.bovis_AF2122/97 LARYGR---SIPHSGEDSIPPNLFVSAQRATS-----
Rv3767c|M.tuberculosis_H37Rv LARYGR---SIPHSGEDSIPPNLFVSAQRATS-----
Mvan_0104|M.vanbaalenii_PYR-1 MRRLHR---LVEIADGDDQSFSTFTTAVKR-------
MAB_4585c|M.abscessus_ATCC_199 AERYGVRHPEVPEDIRELAGAMHYLTCTLPA------
MMAR_2791|M.marinum_M EAGYGMTP-PAVDVRLDAIMHSEYIVATKP-------
MUL_2961|M.ulcerans_Agy99 EAGYGMTP-PAVDVRLDAIMHSEYIVATKP-------
MLBr_02020|M.leprae_Br4923 QTSYGMTP-PDVDVQMDSFMHSQYITATR--------
.