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M. leprae Br4923 MLBr_02020 (-)

annotation: hypothetical protein MLBr_02020
coordinates: 2411240 - 2412154
length: 304

LMAATPEFGSLRSDDDHWDIVSSVGYTALLVAGWRALHAVGPQPLVRDEYAKYFITASRDPYLMNLLANP
GTSLNETAFPRLYGVQTRFFDDFFSSAGDTGIRQAVIVAAGLDSRAYRLKWPNGATVFEIDLPKVLEFKA
RVLAEQGAIPNAGRSEVAADLRADWPRALKAAGFDPQRSSAWSVEGLLPYLTNDAQSALFTRIGELCAPG
SRIAVGALGSRLDRKQLAALEATHPGVNISGDVDFSALTYEPKTDSAQWLAAHGWAVEPVRNTLELQTSY
GMTPPDVDVQMDSFMHSQYITATR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_02020--100% (304)hypothetical protein MLBr_02020
M. leprae Br4923MLBr_02640-7e-5440.97% (310) hypothetical protein MLBr_02640

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1931c-1e-13778.00% (300) hypothetical protein Mb1931c
M. gilvum PYR-GCKMflv_0743-5e-5645.45% (275) putative methyltransferase
M. tuberculosis H37RvRv1896c-1e-13778.00% (300) hypothetical protein Rv1896c
M. abscessus ATCC 19977MAB_4584c-1e-6647.21% (305) hypothetical protein MAB_4584c
M. marinum MMMAR_2791-1e-13075.33% (300) hypothetical protein MMAR_2791
M. avium 104MAV_2803-1e-13577.33% (300) methyltransferase, putative, family protein
M. smegmatis MC2 155MSMEG_0093-5e-5743.60% (289) methyltransferase
M. thermoresistible (build 8)TH_4502-3e-5942.90% (317) PUTATIVE methyltransferase
M. ulcerans Agy99MUL_2961-1e-12774.33% (300) hypothetical protein MUL_2961
M. vanbaalenii PYR-1Mvan_0104-1e-5745.61% (285) putative methyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mb1931c|M.bovis_AF2122/97           --MTTPEYGSL-RSDDDHWDIVSNVGYTALLVAGWRALHTTGPKPLVQDE
Rv1896c|M.tuberculosis_H37Rv        --MTTPEYGSL-RSDDDHWDIVSNVGYTALLVAGWRALHTTGPKPLVQDE
MLBr_02020|M.leprae_Br4923          MMAATPEFGSL-RSDDDHWDIVSSVGYTALLVAGWRALHAVGPQPLVRDE
MAV_2803|M.avium_104                --MTTPQFGSQ-RSDDDNWDIVSSVGYTALLVAGWRALHAVSPRPLVRDD
MMAR_2791|M.marinum_M               --MTTSEYGSR-RSDDDQWDIVSGVGYTALLVAGWRALDTVGPQPLAPDE
MUL_2961|M.ulcerans_Agy99           --MTTSEYGSR-RSDDDQWDIVSGVGYTALLVAGWRALDTVGPQPLAPDE
MAB_4584c|M.abscessus_ATCC_199      --MTNIEDKDWSRSEGDSWDIVSSVGFTALGVAAARAVENREADPLVRDP
Mflv_0743|M.gilvum_PYR-GCK          --------MSSLRTDDDTWDIASSVGATAVMVAAARAAETERHDALINDP
Mvan_0104|M.vanbaalenii_PYR-1       --------MSSLRTDNDTWDIASSVGATAVMVAAARAAETERPEPLIDDP
TH_4502|M.thermoresistible__bu      --------MSSLRTDDDTWDIATSVGSTAVMVAASRAAETEREDALIRDP
MSMEG_0093|M.smegmatis_MC2_155      --MTDVRETPSVRSARDSWGITESVGATALGVAAARAAETAQADPLIRDE
                                                *:  * *.*. .** **: **. ** .     .*  * 

Mb1931c|M.bovis_AF2122/97           YAKHFITASADPYLEGLLANP------RTSEDGTAFPRLYG----VQTRF
Rv1896c|M.tuberculosis_H37Rv        YAKHFITASADPYLEGLLANP------RTSEDGTAFPRLYG----VQTRF
MLBr_02020|M.leprae_Br4923          YAKYFITASRDPYLMNLLANP------GTSLNETAFPRLYG----VQTRF
MAV_2803|M.avium_104                YAKTFIAASGDPYLTGVLANP------GTSEDELAFPRLYG----VQTRF
MMAR_2791|M.marinum_M               YAKYFIAASGDAYLNDQLAHP------PTSVDETAFPRLYG----VQTRF
MUL_2961|M.ulcerans_Agy99           YAKYFIAASGDAYLNDQLAHP------PTSVDETAFPRLYG----VQTRF
MAB_4584c|M.abscessus_ATCC_199      YAEHFVRAAGEPHLIGLLDSSE-----PKPPNPGTAPRHIG----LRSKF
Mflv_0743|M.gilvum_PYR-GCK          YAKVLVEGAGAGAWRFIADEDLVAKASESDTEVGALFEHMKNYQAVRTHF
Mvan_0104|M.vanbaalenii_PYR-1       YAKILVAGAGNGAWQYIADDGFVAKVTESDPEIGPLFEHMKNYQAVRTHF
TH_4502|M.thermoresistible__bu      YAKVLVAGAGTGVWELILDDDFTAKIEAADPETAAIFDHMGNYQAVRTHF
MSMEG_0093|M.smegmatis_MC2_155      FAFLLVSAAGP-TWAQMAVSD--PHWLGADADARRIHEISRNYQAVRTHY
                                    :*  :: .:                      :             :::::

Mb1931c|M.bovis_AF2122/97           FDDFFNCADEAGIRQAVIVAAGLDCRAYRLDWQPGTTVFEIDVPKVLEFK
Rv1896c|M.tuberculosis_H37Rv        FDDFFNCADEAGIRQAVIVAAGLDCRAYRLDWQPGTTVFEIDVPKVLEFK
MLBr_02020|M.leprae_Br4923          FDDFFSSAGDTGIRQAVIVAAGLDSRAYRLKWPNGATVFEIDLPKVLEFK
MAV_2803|M.avium_104                FDDFFDAAGAAGIRQAVIIAAGLDSRAYRLEWPPATTVFEVDLAKVLEFK
MMAR_2791|M.marinum_M               FDDFFRSAAAAGTKQAVIVAAGLDSRAYRLEWPSGTTVFEIDLPQVLEFK
MUL_2961|M.ulcerans_Agy99           FDDFFR-SAAAGTKQAVIVAAGLDSRAYRLEWPSGTTVFEIDLAQVLEFK
MAB_4584c|M.abscessus_ATCC_199      FDEFFINATNSGCKQAVILAAGLDVRAHRLPWPAGTKVFELDQPQVLEFK
Mflv_0743|M.gilvum_PYR-GCK          FDAFFSAAVDAGVRQIVILASGLDSRAFRLPWPAGTVVYEIDQPLVLDYK
Mvan_0104|M.vanbaalenii_PYR-1       FDAFFAAAVDAGIRQIVILASGLDSRAFRLPWPAGTTVFEIDQPLVLAYK
TH_4502|M.thermoresistible__bu      FDTYFARAAEAGIRQVVILASGLDSRAYRLPWPDGTVVYEIDQPKVLEYK
MSMEG_0093|M.smegmatis_MC2_155      FDEYFSDVAHAGIRQVVILAAGLDSRAFRLDWPAGTTVFEIDQPKVLEYK
                                    ** :*     :* :* **:*:*** **.** *  .: *:*:* . ** :*

Mb1931c|M.bovis_AF2122/97           ARVLSERGAVPKAHRVAVPADLRTDWPTPLTAAGFDPQRPSAWSVEGLLP
Rv1896c|M.tuberculosis_H37Rv        ARVLSERGAVPKAHRVAVPADLRTDWPTPLTAAGFDPQRPSAWSVEGLLP
MLBr_02020|M.leprae_Br4923          ARVLAEQGAIPNAGRSEVAADLRADWPRALKAAGFDPQRSSAWSVEGLLP
MAV_2803|M.avium_104                ARVLGEQGAVPKARRVEVAADLRADWSRPLEAAGFDVESPSAWSVEGLLP
MMAR_2791|M.marinum_M               ARVLQRHGVEPKARRNEVAADLRTDWPATLHAAGFEPGQPSAWSVEGLLP
MUL_2961|M.ulcerans_Agy99           ARVLQRHGVEPKARRNAVAADLRTDWPATLHAAGFEPGQPSAWSVEGLLP
MAB_4584c|M.abscessus_ATCC_199      DRVLAEHDATPTSDRREIAVDLRDDWPAALLAAGFDPEVPTAWSAEGLII
Mflv_0743|M.gilvum_PYR-GCK          SSTLAAHGVAPTAERREVPIDLRQDWPAALVATGFDPARPTAWLAEGLLM
Mvan_0104|M.vanbaalenii_PYR-1       SSTLASHGVQPTADRREVPIDLRQDWPTALTHAGFDADQPTAWLAEGLLM
TH_4502|M.thermoresistible__bu      SATLAAHGVQPAADRREVAVDLRHDWPKALRAKGFDPQQRTAWLAEGLLM
MSMEG_0093|M.smegmatis_MC2_155      TATLDAHGAVAKARYVPVPADLRDDWPAALVEAGFDPAQPTAWLAEGLLP
                                      .*  :.. . :    :. *** **. .*   **:    :** .***: 

Mb1931c|M.bovis_AF2122/97           YLTGDAQYALFARIDELCAPGSRVALGALGSRLD------HEQLAALETA
Rv1896c|M.tuberculosis_H37Rv        YLTGDAQYALFARIDELCAPGSRVALGALGSRLD------HEQLAALETA
MLBr_02020|M.leprae_Br4923          YLTNDAQSALFTRIGELCAPGSRIAVGALGSRLD------RKQLAALEAT
MAV_2803|M.avium_104                YLTDEAQHALFTRISGLSAPGSRIAIGALGSRLD------HDQLHALEES
MMAR_2791|M.marinum_M               YLTADAQDALFARIDDLCAPGSRIATGALGSRLD------HDQLVALEQT
MUL_2961|M.ulcerans_Agy99           YLTADAQDALFARIDDLCAPGSRIATGALGSRLD------HDQLVALEQT
MAB_4584c|M.abscessus_ATCC_199      YLPSAAQDLLFERVVALSAPGSQVAVEATRGRPD------IAKWGEMQKK
Mflv_0743|M.gilvum_PYR-GCK          YLPADAQDRLFAQITELSAPGSQVAAESMGVHAP----DRRERMRERFAS
Mvan_0104|M.vanbaalenii_PYR-1       YLPADAQDRLFAQITELSAPGSRVAAESMGIHAQ----DRRERMRERFAS
TH_4502|M.thermoresistible__bu      YLPADAQDRLFENITALSAPGSRLAVETAAEEPV----DRREQMRARMER
MSMEG_0093|M.smegmatis_MC2_155      YLPADAQDRLFELVGVNSAPGSRIAVEAFNMSPERYTEERRAQRRARGEQ
                                    **.  **  **  :   .****::*  :              :       

Mb1931c|M.bovis_AF2122/97           HP--GVNMSGDVNFSALTYDD--KTDPVEWLVEHGWAVDPVRSTLELQVG
Rv1896c|M.tuberculosis_H37Rv        HP--GVNMSGDVNFSALTYDD--KTDPVEWLVEHGWAVDPVRSTLELQVG
MLBr_02020|M.leprae_Br4923          HP--GVNISGDVDFSALTYEP--KTDSAQWLAAHGWAVEPVRNTLELQTS
MAV_2803|M.avium_104                HP--GVDVSGNVDFSALTYEP--QSDPAEWLAAHGWVVDPVRNTLDLQAG
MMAR_2791|M.marinum_M               HP--GVNLSGDVNFSALTYDD--KTNPAQWLAARGWVVEPVRNTLELEAG
MUL_2961|M.ulcerans_Agy99           HP--GVNLFGDVNFSALTYDD--KTNPAQWLAARGWVVEPVRNTLELEAG
MAB_4584c|M.abscessus_ATCC_199      YADEGHPMS-KVDITTLFYDEE-RADVAEWLAARGWKVQGS-HALELAAA
Mflv_0743|M.gilvum_PYR-GCK          IAS-QIDIEP-MDITELTYEDPDRAEVAEWLAAHGWTAQAVPSQDAMRRL
Mvan_0104|M.vanbaalenii_PYR-1       ITA-QFDVEP-MDITELTYEDPDRADVAQWLTAHGWRAEAVPSQDEMRRL
TH_4502|M.thermoresistible__bu      IAS-QFGLEKALDVAQLMYDDPDRADVPEWLTGHGWRTEWVSAPDEMRRL
MSMEG_0093|M.smegmatis_MC2_155      MRK-QLDLDI--DVDALMYTADDRADAAQWLSEHGWQVEAVPSADEMARL
                                           :    :.  * *    :::  :**  :** .:       :   

Mb1931c|M.bovis_AF2122/97           YGLTP---------PDVDVKIDSFMRS-QYITAVRA-
Rv1896c|M.tuberculosis_H37Rv        YGLTP---------PDVDVKIDSFMRS-QYITAVRA-
MLBr_02020|M.leprae_Br4923          YGMTP---------PDVDVQMDSFMHS-QYITATR--
MAV_2803|M.avium_104                YGMTP---------PEVDVKIDGFMRS-QYITAAR--
MMAR_2791|M.marinum_M               YGMTP---------PAVDVRLDAIMHS-EYIVATKP-
MUL_2961|M.ulcerans_Agy99           YGMTP---------PAVDVRLDAIMHS-EYIVATKP-
MAB_4584c|M.abscessus_ATCC_199      YGVEI---------PELPEDVVEVVKQGNYVTAVLPS
Mflv_0743|M.gilvum_PYR-GCK          DRYV----------EVADS--DGQSFS-TFTTGTKL-
Mvan_0104|M.vanbaalenii_PYR-1       HRLV----------EIADG--DDQSFS-TFTTAVKR-
TH_4502|M.thermoresistible__bu      DRFVAAAMPPGDDADAADL--DDTAFS-KFVTAERPS
MSMEG_0093|M.smegmatis_MC2_155      GRPAA-------EADLAEFGMDGVLMR-ARLDGERL-
                                                                    .