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LMAATPEFGSLRSDDDHWDIVSSVGYTALLVAGWRALHAVGPQPLVRDEYAKYFITASRDPYLMNLLANP GTSLNETAFPRLYGVQTRFFDDFFSSAGDTGIRQAVIVAAGLDSRAYRLKWPNGATVFEIDLPKVLEFKA RVLAEQGAIPNAGRSEVAADLRADWPRALKAAGFDPQRSSAWSVEGLLPYLTNDAQSALFTRIGELCAPG SRIAVGALGSRLDRKQLAALEATHPGVNISGDVDFSALTYEPKTDSAQWLAAHGWAVEPVRNTLELQTSY GMTPPDVDVQMDSFMHSQYITATR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. leprae Br4923 | MLBr_02020 | - | - | 100% (304) | hypothetical protein MLBr_02020 |
M. leprae Br4923 | MLBr_02640 | - | 7e-54 | 40.97% (310) | hypothetical protein MLBr_02640 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1931c | - | 1e-137 | 78.00% (300) | hypothetical protein Mb1931c |
M. gilvum PYR-GCK | Mflv_0743 | - | 5e-56 | 45.45% (275) | putative methyltransferase |
M. tuberculosis H37Rv | Rv1896c | - | 1e-137 | 78.00% (300) | hypothetical protein Rv1896c |
M. abscessus ATCC 19977 | MAB_4584c | - | 1e-66 | 47.21% (305) | hypothetical protein MAB_4584c |
M. marinum M | MMAR_2791 | - | 1e-130 | 75.33% (300) | hypothetical protein MMAR_2791 |
M. avium 104 | MAV_2803 | - | 1e-135 | 77.33% (300) | methyltransferase, putative, family protein |
M. smegmatis MC2 155 | MSMEG_0093 | - | 5e-57 | 43.60% (289) | methyltransferase |
M. thermoresistible (build 8) | TH_4502 | - | 3e-59 | 42.90% (317) | PUTATIVE methyltransferase |
M. ulcerans Agy99 | MUL_2961 | - | 1e-127 | 74.33% (300) | hypothetical protein MUL_2961 |
M. vanbaalenii PYR-1 | Mvan_0104 | - | 1e-57 | 45.61% (285) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment Mb1931c|M.bovis_AF2122/97 --MTTPEYGSL-RSDDDHWDIVSNVGYTALLVAGWRALHTTGPKPLVQDE Rv1896c|M.tuberculosis_H37Rv --MTTPEYGSL-RSDDDHWDIVSNVGYTALLVAGWRALHTTGPKPLVQDE MLBr_02020|M.leprae_Br4923 MMAATPEFGSL-RSDDDHWDIVSSVGYTALLVAGWRALHAVGPQPLVRDE MAV_2803|M.avium_104 --MTTPQFGSQ-RSDDDNWDIVSSVGYTALLVAGWRALHAVSPRPLVRDD MMAR_2791|M.marinum_M --MTTSEYGSR-RSDDDQWDIVSGVGYTALLVAGWRALDTVGPQPLAPDE MUL_2961|M.ulcerans_Agy99 --MTTSEYGSR-RSDDDQWDIVSGVGYTALLVAGWRALDTVGPQPLAPDE MAB_4584c|M.abscessus_ATCC_199 --MTNIEDKDWSRSEGDSWDIVSSVGFTALGVAAARAVENREADPLVRDP Mflv_0743|M.gilvum_PYR-GCK --------MSSLRTDDDTWDIASSVGATAVMVAAARAAETERHDALINDP Mvan_0104|M.vanbaalenii_PYR-1 --------MSSLRTDNDTWDIASSVGATAVMVAAARAAETERPEPLIDDP TH_4502|M.thermoresistible__bu --------MSSLRTDDDTWDIATSVGSTAVMVAASRAAETEREDALIRDP MSMEG_0093|M.smegmatis_MC2_155 --MTDVRETPSVRSARDSWGITESVGATALGVAAARAAETAQADPLIRDE *: * *.*. .** **: **. ** . .* * Mb1931c|M.bovis_AF2122/97 YAKHFITASADPYLEGLLANP------RTSEDGTAFPRLYG----VQTRF Rv1896c|M.tuberculosis_H37Rv YAKHFITASADPYLEGLLANP------RTSEDGTAFPRLYG----VQTRF MLBr_02020|M.leprae_Br4923 YAKYFITASRDPYLMNLLANP------GTSLNETAFPRLYG----VQTRF MAV_2803|M.avium_104 YAKTFIAASGDPYLTGVLANP------GTSEDELAFPRLYG----VQTRF MMAR_2791|M.marinum_M YAKYFIAASGDAYLNDQLAHP------PTSVDETAFPRLYG----VQTRF MUL_2961|M.ulcerans_Agy99 YAKYFIAASGDAYLNDQLAHP------PTSVDETAFPRLYG----VQTRF MAB_4584c|M.abscessus_ATCC_199 YAEHFVRAAGEPHLIGLLDSSE-----PKPPNPGTAPRHIG----LRSKF Mflv_0743|M.gilvum_PYR-GCK YAKVLVEGAGAGAWRFIADEDLVAKASESDTEVGALFEHMKNYQAVRTHF Mvan_0104|M.vanbaalenii_PYR-1 YAKILVAGAGNGAWQYIADDGFVAKVTESDPEIGPLFEHMKNYQAVRTHF TH_4502|M.thermoresistible__bu YAKVLVAGAGTGVWELILDDDFTAKIEAADPETAAIFDHMGNYQAVRTHF MSMEG_0093|M.smegmatis_MC2_155 FAFLLVSAAGP-TWAQMAVSD--PHWLGADADARRIHEISRNYQAVRTHY :* :: .: : ::::: Mb1931c|M.bovis_AF2122/97 FDDFFNCADEAGIRQAVIVAAGLDCRAYRLDWQPGTTVFEIDVPKVLEFK Rv1896c|M.tuberculosis_H37Rv FDDFFNCADEAGIRQAVIVAAGLDCRAYRLDWQPGTTVFEIDVPKVLEFK MLBr_02020|M.leprae_Br4923 FDDFFSSAGDTGIRQAVIVAAGLDSRAYRLKWPNGATVFEIDLPKVLEFK MAV_2803|M.avium_104 FDDFFDAAGAAGIRQAVIIAAGLDSRAYRLEWPPATTVFEVDLAKVLEFK MMAR_2791|M.marinum_M FDDFFRSAAAAGTKQAVIVAAGLDSRAYRLEWPSGTTVFEIDLPQVLEFK MUL_2961|M.ulcerans_Agy99 FDDFFR-SAAAGTKQAVIVAAGLDSRAYRLEWPSGTTVFEIDLAQVLEFK MAB_4584c|M.abscessus_ATCC_199 FDEFFINATNSGCKQAVILAAGLDVRAHRLPWPAGTKVFELDQPQVLEFK Mflv_0743|M.gilvum_PYR-GCK FDAFFSAAVDAGVRQIVILASGLDSRAFRLPWPAGTVVYEIDQPLVLDYK Mvan_0104|M.vanbaalenii_PYR-1 FDAFFAAAVDAGIRQIVILASGLDSRAFRLPWPAGTTVFEIDQPLVLAYK TH_4502|M.thermoresistible__bu FDTYFARAAEAGIRQVVILASGLDSRAYRLPWPDGTVVYEIDQPKVLEYK MSMEG_0093|M.smegmatis_MC2_155 FDEYFSDVAHAGIRQVVILAAGLDSRAFRLDWPAGTTVFEIDQPKVLEYK ** :* :* :* **:*:*** **.** * .: *:*:* . ** :* Mb1931c|M.bovis_AF2122/97 ARVLSERGAVPKAHRVAVPADLRTDWPTPLTAAGFDPQRPSAWSVEGLLP Rv1896c|M.tuberculosis_H37Rv ARVLSERGAVPKAHRVAVPADLRTDWPTPLTAAGFDPQRPSAWSVEGLLP MLBr_02020|M.leprae_Br4923 ARVLAEQGAIPNAGRSEVAADLRADWPRALKAAGFDPQRSSAWSVEGLLP MAV_2803|M.avium_104 ARVLGEQGAVPKARRVEVAADLRADWSRPLEAAGFDVESPSAWSVEGLLP MMAR_2791|M.marinum_M ARVLQRHGVEPKARRNEVAADLRTDWPATLHAAGFEPGQPSAWSVEGLLP MUL_2961|M.ulcerans_Agy99 ARVLQRHGVEPKARRNAVAADLRTDWPATLHAAGFEPGQPSAWSVEGLLP MAB_4584c|M.abscessus_ATCC_199 DRVLAEHDATPTSDRREIAVDLRDDWPAALLAAGFDPEVPTAWSAEGLII Mflv_0743|M.gilvum_PYR-GCK SSTLAAHGVAPTAERREVPIDLRQDWPAALVATGFDPARPTAWLAEGLLM Mvan_0104|M.vanbaalenii_PYR-1 SSTLASHGVQPTADRREVPIDLRQDWPTALTHAGFDADQPTAWLAEGLLM TH_4502|M.thermoresistible__bu SATLAAHGVQPAADRREVAVDLRHDWPKALRAKGFDPQQRTAWLAEGLLM MSMEG_0093|M.smegmatis_MC2_155 TATLDAHGAVAKARYVPVPADLRDDWPAALVEAGFDPAQPTAWLAEGLLP .* :.. . : :. *** **. .* **: :** .***: Mb1931c|M.bovis_AF2122/97 YLTGDAQYALFARIDELCAPGSRVALGALGSRLD------HEQLAALETA Rv1896c|M.tuberculosis_H37Rv YLTGDAQYALFARIDELCAPGSRVALGALGSRLD------HEQLAALETA MLBr_02020|M.leprae_Br4923 YLTNDAQSALFTRIGELCAPGSRIAVGALGSRLD------RKQLAALEAT MAV_2803|M.avium_104 YLTDEAQHALFTRISGLSAPGSRIAIGALGSRLD------HDQLHALEES MMAR_2791|M.marinum_M YLTADAQDALFARIDDLCAPGSRIATGALGSRLD------HDQLVALEQT MUL_2961|M.ulcerans_Agy99 YLTADAQDALFARIDDLCAPGSRIATGALGSRLD------HDQLVALEQT MAB_4584c|M.abscessus_ATCC_199 YLPSAAQDLLFERVVALSAPGSQVAVEATRGRPD------IAKWGEMQKK Mflv_0743|M.gilvum_PYR-GCK YLPADAQDRLFAQITELSAPGSQVAAESMGVHAP----DRRERMRERFAS Mvan_0104|M.vanbaalenii_PYR-1 YLPADAQDRLFAQITELSAPGSRVAAESMGIHAQ----DRRERMRERFAS TH_4502|M.thermoresistible__bu YLPADAQDRLFENITALSAPGSRLAVETAAEEPV----DRREQMRARMER MSMEG_0093|M.smegmatis_MC2_155 YLPADAQDRLFELVGVNSAPGSRIAVEAFNMSPERYTEERRAQRRARGEQ **. ** ** : .****::* : : Mb1931c|M.bovis_AF2122/97 HP--GVNMSGDVNFSALTYDD--KTDPVEWLVEHGWAVDPVRSTLELQVG Rv1896c|M.tuberculosis_H37Rv HP--GVNMSGDVNFSALTYDD--KTDPVEWLVEHGWAVDPVRSTLELQVG MLBr_02020|M.leprae_Br4923 HP--GVNISGDVDFSALTYEP--KTDSAQWLAAHGWAVEPVRNTLELQTS MAV_2803|M.avium_104 HP--GVDVSGNVDFSALTYEP--QSDPAEWLAAHGWVVDPVRNTLDLQAG MMAR_2791|M.marinum_M HP--GVNLSGDVNFSALTYDD--KTNPAQWLAARGWVVEPVRNTLELEAG MUL_2961|M.ulcerans_Agy99 HP--GVNLFGDVNFSALTYDD--KTNPAQWLAARGWVVEPVRNTLELEAG MAB_4584c|M.abscessus_ATCC_199 YADEGHPMS-KVDITTLFYDEE-RADVAEWLAARGWKVQGS-HALELAAA Mflv_0743|M.gilvum_PYR-GCK IAS-QIDIEP-MDITELTYEDPDRAEVAEWLAAHGWTAQAVPSQDAMRRL Mvan_0104|M.vanbaalenii_PYR-1 ITA-QFDVEP-MDITELTYEDPDRADVAQWLTAHGWRAEAVPSQDEMRRL TH_4502|M.thermoresistible__bu IAS-QFGLEKALDVAQLMYDDPDRADVPEWLTGHGWRTEWVSAPDEMRRL MSMEG_0093|M.smegmatis_MC2_155 MRK-QLDLDI--DVDALMYTADDRADAAQWLSEHGWQVEAVPSADEMARL : :. * * ::: :** :** .: : Mb1931c|M.bovis_AF2122/97 YGLTP---------PDVDVKIDSFMRS-QYITAVRA- Rv1896c|M.tuberculosis_H37Rv YGLTP---------PDVDVKIDSFMRS-QYITAVRA- MLBr_02020|M.leprae_Br4923 YGMTP---------PDVDVQMDSFMHS-QYITATR-- MAV_2803|M.avium_104 YGMTP---------PEVDVKIDGFMRS-QYITAAR-- MMAR_2791|M.marinum_M YGMTP---------PAVDVRLDAIMHS-EYIVATKP- MUL_2961|M.ulcerans_Agy99 YGMTP---------PAVDVRLDAIMHS-EYIVATKP- MAB_4584c|M.abscessus_ATCC_199 YGVEI---------PELPEDVVEVVKQGNYVTAVLPS Mflv_0743|M.gilvum_PYR-GCK DRYV----------EVADS--DGQSFS-TFTTGTKL- Mvan_0104|M.vanbaalenii_PYR-1 HRLV----------EIADG--DDQSFS-TFTTAVKR- TH_4502|M.thermoresistible__bu DRFVAAAMPPGDDADAADL--DDTAFS-KFVTAERPS MSMEG_0093|M.smegmatis_MC2_155 GRPAA-------EADLAEFGMDGVLMR-ARLDGERL- .