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M. thermoresistible (build 8) TH_2706 (-)

annotation: putative methyltransferase
coordinates: 674825 - 675757
length: 311

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2706--100% (311)putative methyltransferase
M. thermoresistible (build 8)TH_0301-5e-7958.98% (256) CONSERVED HYPOTHETICAL PROTEIN
M. thermoresistible (build 8)TH_4502-6e-6445.57% (316) PUTATIVE methyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0747c-1e-8460.22% (269) hypothetical protein Mb0747c
M. gilvum PYR-GCKMflv_5025-6e-9661.59% (289) putative methyltransferase
M. tuberculosis H37RvRv0726c-1e-8460.22% (269) hypothetical protein Rv0726c
M. leprae Br4923MLBr_02640-1e-6447.57% (309) hypothetical protein MLBr_02640
M. abscessus ATCC 19977MAB_3787-3e-8255.75% (287) hypothetical protein MAB_3787
M. marinum MMMAR_1068-1e-10362.33% (300) O-methyltransferase
M. avium 104MAV_4435-6e-9860.13% (301) methyltransferase, putative, family protein
M. smegmatis MC2 155MSMEG_1481-1e-10563.73% (306) methyltransferase
M. ulcerans Agy99MUL_0816-3e-9057.75% (284) O-methyltransferase
M. vanbaalenii PYR-1Mvan_1344-2e-9159.86% (289) putative methyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


TH_2706|M.thermoresistible__bu      MARS-----ESDTWDLTSGVGVTATMVAAARALASREPEPLIDDPFAAPL
MSMEG_1481|M.smegmatis_MC2_155      MART-----DTDSWDLASSVGATATMVAAARAIASTEPNALIDDPYAADL
MMAR_1068|M.marinum_M               MTRT-----DQDSWDLASSVGATATMVAAARALASAEANPIIDDPFAAPL
MAV_4435|M.avium_104                MTRT-----DQDSWDLASSVGATATMVAAARALASTGERPIINDPFAAPL
Mflv_5025|M.gilvum_PYR-GCK          MART-----PDDSWDLASSVGATATMVAAGRAVASADPDPLINDPYAEPL
Mvan_1344|M.vanbaalenii_PYR-1       MART-----ADDSWDPASSVGATATMVAAGRAAASADPDPLINDPYAEPL
MUL_0816|M.ulcerans_Agy99           MART-----HDDKWDLASSVGATATIVAAGRAMASRDPRGLIDDPFAEPL
MAB_3787|M.abscessus_ATCC_1997      MART-----DDDSWDLASSVGATATMVAAQRALASHVPNPLINDPYAEPL
Mb0747c|M.bovis_AF2122/97           MTYTGSIRCEGDTWDLASSVGATATMVAAARAMATRAANPLINDQFAEPL
Rv0726c|M.tuberculosis_H37Rv        MTYTGSIRCEGDTWDLASSVGATATMVAAARAMATRAANPLINDQFAEPL
MLBr_02640|M.leprae_Br4923          -MRT-----HDDTWDIKTSVGTTAVMVAAARAAETDRPDALIRDPYAKLL
                                       :       *.**  :.**.**.:*** **  :     :* * :*  *

TH_2706|M.thermoresistible__bu      VRAVGV-EFFTRLVDGDLELP--ADTAEERAAAQVLTEVMAVRTRFFDDF
MSMEG_1481|M.smegmatis_MC2_155      VRKVGL-EFFTKLVDGDIALD--GD---DAAAAGLMVSMMAVRTRFFDDF
MMAR_1068|M.marinum_M               VRAVGL-DFFTRLAEGEID----HDEQAQRDR-QLVADSIAVRTRFFDDF
MAV_4435|M.avium_104                VRAVGL-DFFRRLVDGEVAPA--DPQRGERDL-QLETDSIAVRTRFFDDF
Mflv_5025|M.gilvum_PYR-GCK          VRAVGL-DFFTRMLDGELDLSVFPDSSPE--RAQAMIDGMAVRTRFFDDC
Mvan_1344|M.vanbaalenii_PYR-1       VRAVGL-SFFTKMLDGELDLSQFADGSPE--RVQAMIDGMAVRTRFFDDC
MUL_0816|M.ulcerans_Agy99           VRAVGV-DFFIKMMDGEFDLSVLQNVSSA--KAQAMVDGMAVRTKYFDDY
MAB_3787|M.abscessus_ATCC_1997      VRAVGI-EYFTKLASGAFDPEQMAGLVQLGITADGMANGMASRTWYYDTA
Mb0747c|M.bovis_AF2122/97           VRAVGV-DVLTRLASGELTASDIDDPERPNASMVRMAEHHAVRTKFFDEF
Rv0726c|M.tuberculosis_H37Rv        VRAVGV-DVLTRLASGELTASDIDDPERPNASMVRMAEHHAVRTKFFDEF
MLBr_02640|M.leprae_Br4923          VTNTGAGALWEAMLDPSMVAKVEAIDAEAAAMVEHMRSYQAVRTNFFDTY
                                    *  .*       : .  .                   .  * ** ::*  

TH_2706|M.thermoresistible__bu      FTDATRVGARQAVILASGLDARAYRLTWPDGTVVYEIDQPEVIAFKTRTL
MSMEG_1481|M.smegmatis_MC2_155      FCDAAGAGIRQSVILAAGLDSRAYRLGWPAGTVVYEIDQPRVIEAKTAAM
MMAR_1068|M.marinum_M               FLDAARRGVRQSVILAAGLDARAYRLPWPSGSVVYEVDQPDVIDFKDTTM
MAV_4435|M.avium_104                FTGAARDGIRQSVILAAGLDARAYRLDWPAGAVVYEVDQPKVVEFKTNTM
Mflv_5025|M.gilvum_PYR-GCK          CLAAASAGVRQVVILAAGLDARTYRLPWPDGTVVYELDQPDVIAFKTQTL
Mvan_1344|M.vanbaalenii_PYR-1       CGTSTTAGITQVVILASGLDARAYRLGWPAGTVVYELDQPAVIEFKTRTL
MUL_0816|M.ulcerans_Agy99           FGDAIKSGIRQAVILASGLDARAYRLPWPADTVVYELDQPQVIEFKTNVL
MAB_3787|M.abscessus_ATCC_1997      FESSTAAGVRQAVILASGLDTRAYRLTWPAGTTVYELDQPEVITFKTDTL
Mb0747c|M.bovis_AF2122/97           FMDATRAGIRQVVILASGLDSRAYRLAWPAQTVVYEIDQPQVMEFKTRTL
Rv0726c|M.tuberculosis_H37Rv        FMDATRAGIRQVVILASGLDSRAYRLAWPAQTVVYEIDQPQVMEFKTRTL
MLBr_02640|M.leprae_Br4923          FNNAVIDGIRQFVILASGLDSRAYRLDWPTGTTVYEIDQPKVLAYKSTTL
                                       :   *  * ****:***:*:*** **  :.***:*** *:  *  .:

TH_2706|M.thermoresistible__bu      AELGAPPTAPHRPVAVDLRDDWPAALTAAGFDPTVATAWSAEGLLRYLPP
MSMEG_1481|M.smegmatis_MC2_155      AEIGASPTAERRTVAVDLRDDWPAALRAAGFDAATPTAWIAEGLLVYLPP
MMAR_1068|M.marinum_M               SALGAVPTATRRTVRVDLRDDWPAALRHNGFDTTQPTAWSAEGLLMYLPP
MAV_4435|M.avium_104                AALDARPAAQLRTVSIDLREDWPEALRANGFDVTQATSWSAEGLLMYLPP
Mflv_5025|M.gilvum_PYR-GCK          RNLGAEPAATQRPVPVDLREDWPAALRAAGFDATRPTAWLAEGLLIYLPP
Mvan_1344|M.vanbaalenii_PYR-1       AGLGAHPTATHRPVPIDLREDWPAALHAAGFDASRPTAWLAEGLLIYLPP
MUL_0816|M.ulcerans_Agy99           ADLGAEPRATRRAIPIDLRGDWPVALRAAGLDTTAPTAWLAEGLLIYLPP
MAB_3787|M.abscessus_ATCC_1997      AELGASPSAERRTVAIDLREDWPAALQAAGFDPEQPTVWSAEGLLIYLPP
Mb0747c|M.bovis_AF2122/97           AELGATPTADRRVVTADLRADWPTALGAAGFDPTQPTAWSAEGLLRYLPP
Rv0726c|M.tuberculosis_H37Rv        AELGATPTADRRVVTADLRADWPTALGAAGFDPTQPTAWSAEGLLRYLPP
MLBr_02640|M.leprae_Br4923          AEHGVTPTADRREVPIDLRQDWPPALRSAGFDPSARTAWLAEGLLMYLPA
                                       .. * *  * :  *** *** **   *:*    * * ***** ***.

TH_2706|M.thermoresistible__bu      DAQDRLFDHITDLSAPGSRLATEDHPGP----GAGLGEKADELGRRWREH
MSMEG_1481|M.smegmatis_MC2_155      EAQDRLFDNITALSARGSRLATEYHPDI----TSTLRGRGQAMSERWRDH
MMAR_1068|M.marinum_M               DAQDRLFDAISGLSAPGSRLATEYHPDP----GSTMAERAQQFNQRWVRL
MAV_4435|M.avium_104                EAQDRLFDNITALSAPGSRLATEYHPDAT---GTTMAQRAQEFNDRWARV
Mflv_5025|M.gilvum_PYR-GCK          EAQDALFDTVTALSAPGSTLATEYVPGIV---DFDG-AKARALSEPLREH
Mvan_1344|M.vanbaalenii_PYR-1       EAQDQLFDRITALSAPGSTIATEYAPGII---DFDD-EKARAMSAPMREM
MUL_0816|M.ulcerans_Agy99           EAQDRLFDNITALSAPGSTVATEFVPGIV---DFDV-DRARQMSGPFRDH
MAB_3787|M.abscessus_ATCC_1997      EAQDRLFASITELSAPGSRLVCEQVPGLE---TADF-SKARELTRQFAGE
Mb0747c|M.bovis_AF2122/97           EAQDRLLDNVTALSVPDSRFATESIRNFKPHHEERMRERMTILANRWRAY
Rv0726c|M.tuberculosis_H37Rv        EAQDRLLDNVTALSVPDSRFATESIRNFKPHHEERMRERMTILANRWRAY
MLBr_02640|M.leprae_Br4923          TAQDGLFTEIGGLSAVGSRIAVETSPLHGDEWREQMQLRFRRVSDALG-F
                                     *** *:  :  **. .* .. *               :   .       

TH_2706|M.thermoresistible__bu      GFEVQLSELFHPGE-RTPVVDYLRGRGWDARARPRAEVFAG---------
MSMEG_1481|M.smegmatis_MC2_155      GFDVDLSDLWYGGD-RNAADEYLAGHGWQVSTRPRPEVFAA---------
MMAR_1068|M.marinum_M               GCDIDLSGLFYEGE-RSNVVDYLTEHGWHVAARPRQDLFTD---------
MAV_4435|M.avium_104                GCDIDLSGLFFDGE-RSNVVEYLTGRGWRVSARPRRDLFDD---------
Mflv_5025|M.gilvum_PYR-GCK          GLDIDMPSLVYTGA-RTPVMDHLRGAGWQVSGTARAELFAR---------
Mvan_1344|M.vanbaalenii_PYR-1       GLDIDMPSLVYAGT-RSHVMDYLAGQGWEVTGVPRRELFTR---------
MUL_0816|M.ulcerans_Agy99           GLDIDMSSLVYTGA-RNHVVDYLRAKGWDAEGVTRSKLFER---------
MAB_3787|M.abscessus_ATCC_1997      TLDLDLESLVYTQE-RQMAADWLAEHGWTVITEENDELYAR---------
Mb0747c|M.bovis_AF2122/97           GFDLDMNELVYFGD-RNEPASYLSDNGWLLTEIKSQDLLTANGFQPFEDE
Rv0726c|M.tuberculosis_H37Rv        GFDLDMNELVYFGD-RNEPASYLSDNGWLLTEIKSQDLLTANGFQPFEDE
MLBr_02640|M.leprae_Br4923          EQAVDVQELIYHDENRAVVADWLNRHGWRATAQSAPDEMRRVG-------
                                       :::  * .    *    . *   **        .             

TH_2706|M.thermoresistible__bu      -----------------------YGREFPDSAAL----AAMRDSSAVTAV
MSMEG_1481|M.smegmatis_MC2_155      -----------------------YGRTFPDLTLTGDDNAAMRQSVAITAT
MMAR_1068|M.marinum_M               -----------------------YGRVFP-DADT----SQLRSIVAVTAT
MAV_4435|M.avium_104                -----------------------YGLAYPEDDET----AQFPNIVAVSAE
Mflv_5025|M.gilvum_PYR-GCK          -----------------------FGRPLPQDADGT---DPLGEIVYVSAT
Mvan_1344|M.vanbaalenii_PYR-1       -----------------------YGRPLPPEAGDT---DPLGEIVYVSAH
MUL_0816|M.ulcerans_Agy99           -----------------------NGMAVPAPSDD----DPLGEIIFISAA
MAB_3787|M.abscessus_ATCC_1997      -----------------------LNLDPPNPLLR----SIFPNIVYVDAT
Mb0747c|M.bovis_AF2122/97           EVPLPDFFYVSARLQRKHRQYPAHRKPAPSWRHTACPVNELSKSAAYTMT
Rv0726c|M.tuberculosis_H37Rv        EVPLPDFFYVSARLQRKHRQYPAHRKPAPSWRHTACPVNELSKSAAYTMT
MLBr_02640|M.leprae_Br4923          ----------------------RWGDGVPMADDK----DAFAEFVTAHRL
                                                                *           : .       

TH_2706|M.thermoresistible__bu      RPVVRAGMR----------
MSMEG_1481|M.smegmatis_MC2_155      RS-----------------
MMAR_1068|M.marinum_M               FGEAG--------------
MAV_4435|M.avium_104                LG-----------------
Mflv_5025|M.gilvum_PYR-GCK          LAADA--------------
Mvan_1344|M.vanbaalenii_PYR-1       RPQ----------------
MUL_0816|M.ulcerans_Agy99           LTG----------------
MAB_3787|M.abscessus_ATCC_1997      LG-----------------
Mb0747c|M.bovis_AF2122/97           RSDAHQASTTAPPPPGLTG
Rv0726c|M.tuberculosis_H37Rv        RSDAHQASTTAPPPPGLTG
MLBr_02640|M.leprae_Br4923          -------------------