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PRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTLLAGATDLDP DLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRLPWPDGTVVYELDQPKVLEFKS ATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCAWLAEGLVRYLPARAQDLLFERIDALSRPG SWLASNVPGAGFLDPERMRRQRADMRRMRAAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTAT LPELLARYGRSIPHSGEDSIPPNLFVSAQRATS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3767c | - | - | 100% (314) | hypothetical protein Rv3767c |
| M. tuberculosis H37Rv | Rv0146 | - | 1e-71 | 47.45% (314) | hypothetical protein Rv0146 |
| M. tuberculosis H37Rv | Rv0145 | - | 2e-67 | 50.17% (293) | hypothetical protein Rv0145 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3793c | - | 0.0 | 100.00% (314) | hypothetical protein Mb3793c |
| M. gilvum PYR-GCK | Mflv_0743 | - | 5e-78 | 50.67% (298) | putative methyltransferase |
| M. leprae Br4923 | MLBr_02640 | - | 6e-67 | 46.55% (290) | hypothetical protein MLBr_02640 |
| M. abscessus ATCC 19977 | MAB_3886c | - | 7e-84 | 51.45% (311) | hypothetical protein MAB_3886c |
| M. marinum M | MMAR_5323 | - | 1e-135 | 73.63% (311) | O-methyltransferase |
| M. avium 104 | MAV_0301 | - | 1e-143 | 78.46% (311) | methyltransferase, putative, family protein |
| M. smegmatis MC2 155 | MSMEG_0095 | - | 9e-76 | 49.20% (311) | methyltransferase |
| M. thermoresistible (build 8) | TH_4502 | - | 2e-76 | 49.38% (320) | PUTATIVE methyltransferase |
| M. ulcerans Agy99 | MUL_4402 | - | 1e-136 | 73.95% (311) | O-methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_0104 | - | 2e-75 | 48.70% (308) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0095|M.smegmatis_MC2_155 MSSLRTDDDTWDIATSVGSTAVMVAAARAGETERDDALIRDPYAKILVAG
TH_4502|M.thermoresistible__bu MSSLRTDDDTWDIATSVGSTAVMVAASRAAETEREDALIRDPYAKVLVAG
Mflv_0743|M.gilvum_PYR-GCK MSSLRTDDDTWDIASSVGATAVMVAAARAAETERHDALINDPYAKVLVEG
Mvan_0104|M.vanbaalenii_PYR-1 MSSLRTDNDTWDIASSVGATAVMVAAARAAETERPEPLIDDPYAKILVAG
MLBr_02640|M.leprae_Br4923 ---MRTHDDTWDIKTSVGTTAVMVAAARAAETDRPDALIRDPYAKLLVTN
Rv3767c|M.tuberculosis_H37Rv --MPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDA
Mb3793c|M.bovis_AF2122/97 --MPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDA
MAV_0301|M.avium_104 --MPRTDNDSWDITQSVGATALGVAAARAAETESENPLISDPFARIFVDA
MMAR_5323|M.marinum_M --MPRTDNDSWTITESVGATALGVAAARAAETESENPLIEDPFARVFVDA
MUL_4402|M.ulcerans_Agy99 --MPRTDNDSWTITESVGATALGVAAARAAETESENPLIEDPFARVFVDA
MAB_3886c|M.abscessus_ATCC_199 --MARRDGDSWEITESVGTTALGVASARDAETRSPNPLISDPYAGHFLAA
* ..*:* * ***:**: **::* .** :.** **:* ::
MSMEG_0095|M.smegmatis_MC2_155 AGTG-VWETV-LDSEFAAKIENLDPEAAAIFAHMGNYQAVRTHFFDAYYR
TH_4502|M.thermoresistible__bu AGTG-VWELI-LDDDFTAKIEAADPETAAIFDHMGNYQAVRTHFFDTYFA
Mflv_0743|M.gilvum_PYR-GCK AGAG-AWRFI-ADEDLVAKASESDTEVGALFEHMKNYQAVRTHFFDAFFS
Mvan_0104|M.vanbaalenii_PYR-1 AGNG-AWQYI-ADDGFVAKVTESDPEIGPLFEHMKNYQAVRTHFFDAFFA
MLBr_02640|M.leprae_Br4923 TGAGALWEAM-LDPSMVAKVEAIDAEAAAMVEHMRSYQAVRTNFFDTYFN
Rv3767c|M.tuberculosis_H37Rv AGDG-IWSMY-TNRTLLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFL
Mb3793c|M.bovis_AF2122/97 AGDG-IWSMY-TNRTLLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFL
MAV_0301|M.avium_104 AGKG-MWSIY-ADPALLTKADDLEPDLRGRLQLMIDFMATRTAFFDEFFL
MMAR_5323|M.marinum_M AGDG-MWSMF-ANPALLAGAPEIESQVGARVRQMIDFMATRTAFFDEFFL
MUL_4402|M.ulcerans_Agy99 AGDG-MWSMF-ANPALLAGAPEIESQVGARVRQMIDFMATRTAFFDEFFL
MAB_3886c|M.abscessus_ATCC_199 AGDG-AWNAYRFDGEPPAALVEAEPRLVERIDAMRSYVACRTKFFDDFFG
:* * * : : :. . * .: * ** *** ::
MSMEG_0095|M.smegmatis_MC2_155 EAADAGIRQIVILASGLDSRAYRLDWPAGTTVYEIDQPKVLEYKSATLRE
TH_4502|M.thermoresistible__bu RAAEAGIRQVVILASGLDSRAYRLPWPDGTVVYEIDQPKVLEYKSATLAA
Mflv_0743|M.gilvum_PYR-GCK AAVDAGVRQIVILASGLDSRAFRLPWPAGTVVYEIDQPLVLDYKSSTLAA
Mvan_0104|M.vanbaalenii_PYR-1 AAVDAGIRQIVILASGLDSRAFRLPWPAGTTVFEIDQPLVLAYKSSTLAS
MLBr_02640|M.leprae_Br4923 NAVIDGIRQFVILASGLDSRAYRLDWPTGTTVYEIDQPKVLAYKSTTLAE
Rv3767c|M.tuberculosis_H37Rv ATADAGVRQVVILASGLDSRAWRLPWPDGTVVYELDQPKVLEFKSATLRQ
Mb3793c|M.bovis_AF2122/97 ATADAGVRQVVILASGLDSRAWRLPWPDGTVVYELDQPKVLEFKSATLRQ
MAV_0301|M.avium_104 AAADAGVRQVVILAAGLDARSWRLPWPDGTVVYELDQPKVLDFKSTTLRE
MMAR_5323|M.marinum_M GAADTGVRQVVILASGLDSRAWRLPWPDGTVVYELDQPRVLEFKSATLRQ
MUL_4402|M.ulcerans_Agy99 GAADAGVRQVVILASGLDSRAWRLPWPDGTVVYELDQPRVLEFKSATLRQ
MAB_3886c|M.abscessus_ATCC_199 DASTSGIRQAVILASGLDARAWRLDWPRDAVLFELDLPRVLAFKAETLDK
: *:** ****:***:*::** ** .:.::*:* * ** :*: **
MSMEG_0095|M.smegmatis_MC2_155 HGIEPVAQRREVPVDLRFDWPTALHDAGFDASLPTAWLAEGLLMYLPAEA
TH_4502|M.thermoresistible__bu HGVQPAADRREVAVDLRHDWPKALRAKGFDPQQRTAWLAEGLLMYLPADA
Mflv_0743|M.gilvum_PYR-GCK HGVAPTAERREVPIDLRQDWPAALVATGFDPARPTAWLAEGLLMYLPADA
Mvan_0104|M.vanbaalenii_PYR-1 HGVQPTADRREVPIDLRQDWPTALTHAGFDADQPTAWLAEGLLMYLPADA
MLBr_02640|M.leprae_Br4923 HGVTPTADRREVPIDLRQDWPPALRSAGFDPSARTAWLAEGLLMYLPATA
Rv3767c|M.tuberculosis_H37Rv HGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCAWLAEGLVRYLPARA
Mb3793c|M.bovis_AF2122/97 HGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCAWLAEGLVRYLPARA
MAV_0301|M.avium_104 HGAQPKAELVNVPIDLRQDWPKALQEAGFDASRPAVWSAEGLVRYLPAQA
MMAR_5323|M.marinum_M HGARPTAQLVNIPIDLRQDWPAALLDSGFDASKPTAWSAEGLVRYLPARA
MUL_4402|M.ulcerans_Agy99 HGARPTAQLMNIPIDLRQDWPAALLDSGFDASKPTAWSAEGLVRYLPARA
MAB_3886c|M.abscessus_ATCC_199 QGATPRIRHVPVAVDLRDDWPAALRAGGFDVGRPAAWIAEGLLPYLPPAA
:* * :.:*** *** ** *** .* ****: ***. *
MSMEG_0095|M.smegmatis_MC2_155 QDRLFELVTELSAPGSRIAVETAGVAATD-----RREAMRERFKKFADQL
TH_4502|M.thermoresistible__bu QDRLFENITALSAPGSRLAVETAAEEPVD-----RREQMRARMERIASQF
Mflv_0743|M.gilvum_PYR-GCK QDRLFAQITELSAPGSQVAAESMGVHAPD-----RRERMRERFASIASQI
Mvan_0104|M.vanbaalenii_PYR-1 QDRLFAQITELSAPGSRVAAESMGIHAQD-----RRERMRERFASITAQF
MLBr_02640|M.leprae_Br4923 QDGLFTEIGGLSAVGSRIAVETSPLHGDE-----WREQMQLRFRRVSDAL
Rv3767c|M.tuberculosis_H37Rv QDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMRAAAAKL
Mb3793c|M.bovis_AF2122/97 QDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMRAAAAKL
MAV_0301|M.avium_104 QDLLFERIDALSVPGSRLASNVPDSGFTDPDRLARQREDMRRMRAAAAKL
MMAR_5323|M.marinum_M QDLLFERIDTLSPAGSWLATNVPQEGFSDPDLVRRQHEEMQRMRAAAGRL
MUL_4402|M.ulcerans_Agy99 QDLLFERIDTLSPAGSWLATNVPQGGFLDPDLVRRQHEEMQRMRAAAGRL
MAB_3886c|M.abscessus_ATCC_199 QDLLFERIDTLSAPGSRIAVENFGEDFFNPETLARQRERGQAFRRVAEEM
** ** : ** ** :* : : :. : : :
MSMEG_0095|M.smegmatis_MC2_155 NLSSALDIQELVYDDPDRADVAEWLDAHGWRARGVHALDEMRRLDRL---
TH_4502|M.thermoresistible__bu GLEKALDVAQLMYDDPDRADVPEWLTGHGWRTEWVSAPDEMRRLDRF---
Mflv_0743|M.gilvum_PYR-GCK DIEP-MDITELTYEDPDRAEVAEWLAAHGWTAQAVPSQDAMRRLDRY---
Mvan_0104|M.vanbaalenii_PYR-1 DVEP-MDITELTYEDPDRADVAQWLTAHGWRAEAVPSQDEMRRLHRL---
MLBr_02640|M.leprae_Br4923 GFEQAVDVQELIYHDENRAVVADWLNRHGWRATAQSAPDEMRRVGRWGDG
Rv3767c|M.tuberculosis_H37Rv VETEISDVDDLWYAE-QRTAVAEWLRERGWDVSTATLPELLARYGRS---
Mb3793c|M.bovis_AF2122/97 VETEISDVDDLWYAE-QRTAVAEWLRERGWDVSTATLPELLARYGRS---
MAV_0301|M.avium_104 VDAEITDFDDLWYPE-ERTPVDSWLRERGWDVSTATFAELMARYGRS---
MMAR_5323|M.marinum_M VEIQMPAVEDLWYAE-ERTPVADWLGEHGWRASATTSAELLTRYGRP---
MUL_4402|M.ulcerans_Agy99 VEIQMPAVEDLWYAE-ERTPVADWLGEHGWRASATTSAELLTRYGRP---
MAB_3886c|M.abscessus_ATCC_199 QGQDIPDVADLWYLE-ERTDAGEFLAGRGWRVTSETAVALLGRHGRD---
. :* * : :*: . .:* :** . : * *
MSMEG_0095|M.smegmatis_MC2_155 VELPDDP---------DRAAFSTFVTAQRL--
TH_4502|M.thermoresistible__bu VAAAMPPGDDADAADLDDTAFSKFVTAERPS-
Mflv_0743|M.gilvum_PYR-GCK VEVADSD----------GQSFSTFTTGTKL--
Mvan_0104|M.vanbaalenii_PYR-1 VEIADGD----------DQSFSTFTTAVKR--
MLBr_02640|M.leprae_Br4923 VPMADDK-----------DAFAEFVTAHRL--
Rv3767c|M.tuberculosis_H37Rv IPHSGED----------SIPPNLFVSAQRATS
Mb3793c|M.bovis_AF2122/97 IPHSGED----------SIPPNLFVSAQRATS
MAV_0301|M.avium_104 IPQGAQD----------SMPPTLYVSAQRRAG
MMAR_5323|M.marinum_M VPDDAEG----------PVPPTLFVSAHRPAA
MUL_4402|M.ulcerans_Agy99 VPDDAEG----------PVPPTLFVSAHRPAA
MAB_3886c|M.abscessus_ATCC_199 IPADLPD----------ATPNSAFLFAQKAD-
: . : . :