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TNIEDKDWSRSEGDSWDIVSSVGFTALGVAAARAVENREADPLVRDPYAEHFVRAAGEPHLIGLLDSSEP KPPNPGTAPRHIGLRSKFFDEFFINATNSGCKQAVILAAGLDVRAHRLPWPAGTKVFELDQPQVLEFKDR VLAEHDATPTSDRREIAVDLRDDWPAALLAAGFDPEVPTAWSAEGLIIYLPSAAQDLLFERVVALSAPGS QVAVEATRGRPDIAKWGEMQKKYADEGHPMSKVDITTLFYDEERADVAEWLAARGWKVQGSHALELAAAY GVEIPELPEDVVEVVKQGNYVTAVLPS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4584c | - | - | 100% (308) | hypothetical protein MAB_4584c |
| M. abscessus ATCC 19977 | MAB_4585c | - | e-101 | 57.47% (308) | hypothetical protein MAB_4585c |
| M. abscessus ATCC 19977 | MAB_0027c | - | 1e-79 | 51.68% (298) | hypothetical protein MAB_0027c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0150 | - | 1e-67 | 46.95% (311) | hypothetical protein Mb0150 |
| M. gilvum PYR-GCK | Mflv_0743 | - | 1e-64 | 48.91% (276) | putative methyltransferase |
| M. tuberculosis H37Rv | Rv0145 | - | 1e-67 | 46.95% (311) | hypothetical protein Rv0145 |
| M. leprae Br4923 | MLBr_02020 | - | 5e-67 | 47.21% (305) | hypothetical protein MLBr_02020 |
| M. marinum M | MMAR_0955 | - | 2e-67 | 49.50% (301) | hypothetical protein MMAR_0955 |
| M. avium 104 | MAV_4557 | - | 4e-68 | 47.51% (301) | methyltransferase, putative, family protein |
| M. smegmatis MC2 155 | MSMEG_1480 | - | 2e-71 | 48.50% (301) | methyltransferase |
| M. thermoresistible (build 8) | TH_2706 | - | 2e-69 | 46.10% (308) | PUTATIVE putative methyltransferase |
| M. ulcerans Agy99 | MUL_0818 | - | 1e-66 | 46.80% (297) | O-methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_0104 | - | 9e-64 | 48.16% (272) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
TH_2706|M.thermoresistible__bu ------------MARSESDTWDLTSGVGVTATMVAAARALASREPEPLID
MUL_0818|M.ulcerans_Agy99 -------MTSTGSTRYDGDSWDLASSVGVTATMVAAARAMATRAENPLIN
MSMEG_1480|M.smegmatis_MC2_155 ------------MTRTDGDTWDLATSVGSTATGVAAMRALATRQPDPLID
Mb0150|M.bovis_AF2122/97 MTELDDVSSLPSSRRTAGDTWAITESVGATALGVAAARAVETAATNPLIR
Rv0145|M.tuberculosis_H37Rv MTELDDVSSLPSSRRTAGDTWAITESVGATALGVAAARAVETAATNPLIR
Mflv_0743|M.gilvum_PYR-GCK ----------MSSLRTDDDTWDIASSVGATAVMVAAARAAETERHDALIN
Mvan_0104|M.vanbaalenii_PYR-1 ----------MSSLRTDNDTWDIASSVGATAVMVAAARAAETERPEPLID
MMAR_0955|M.marinum_M ------------MARTEDDSWEITESVGATALGVASARAAETRSQHPLIS
MAV_4557|M.avium_104 ----------MSTARTDDDSWEITESVGATALGVASARAAETRSENPLIK
MAB_4584c|M.abscessus_ATCC_199 ----MTNIEDKDWSRSEGDSWDIVSSVGFTALGVAAARAVENREADPLVR
MLBr_02020|M.leprae_Br4923 ---MMAATPEFGSLRSDDDHWDIVSSVGYTALLVAGWRALHAVGPQPLVR
* .* * :. .** ** **. ** ..*:
TH_2706|M.thermoresistible__bu DPFAAPLVRAVGVEFFTRLVDGDLELP-ADTAEERAAAQV--LTEVMAVR
MUL_0818|M.ulcerans_Agy99 DPYAEPLVRAVGVDLLTRLATGEFNVADLDDDPQRPLGPIGDVADNMAVR
MSMEG_1480|M.smegmatis_MC2_155 DPYADALVKAVGLEHCIALADGETCVE------GDPMLDLNRMCEQIAVR
Mb0150|M.bovis_AF2122/97 DEFAKVLVSSAGT-AWARLADADLAWLDGD---QLGRRVHRVACDYQAVR
Rv0145|M.tuberculosis_H37Rv DEFAKVLVSSAGT-AWARLADADLAWLDGD---QLGRRVHRVACDYQAVR
Mflv_0743|M.gilvum_PYR-GCK DPYAKVLVEGAGAGAWRFIADEDLVAKASESDTEVG-ALFEHMKNYQAVR
Mvan_0104|M.vanbaalenii_PYR-1 DPYAKILVAGAGNGAWQYIADDGFVAKVTESDPEIG-PLFEHMKNYQAVR
MMAR_0955|M.marinum_M DPFAQVFLDAVGDGVWNWHSAPQLPAELLEIEPDLP-LQMEAMVSYMASR
MAV_4557|M.avium_104 DPFAQVFLDAAGDGVWNWHSAPQLPPELIEAEPTIP-LQQQAMVSYMASR
MAB_4584c|M.abscessus_ATCC_199 DPYAEHFVRAAGEPHLIGLLDSSEPKP----------PNPGTAPRHIGLR
MLBr_02020|M.leprae_Br4923 DEYAKYFITASRDPYLMNLLANP-----------GTSLNETAFPRLYGVQ
* :* :: . . :
TH_2706|M.thermoresistible__bu TRFFDDFFTDATRVGARQAVILASGLDARAYRLTWPDGTVVYEIDQPEVI
MUL_0818|M.ulcerans_Agy99 TRFFDDFFLAATRAGLEQVVILASGRDARAYRLPWPPQTVVYEIDLPQVI
MSMEG_1480|M.smegmatis_MC2_155 TRYFDELFIAAGADGVRQAVILASGLDTRAYRLDWPAGTVVFEVDQPQVI
Mb0150|M.bovis_AF2122/97 THFFDEYFGAAVDAGVRQVVILAAGLDARAYRLNWPAGTVVYEIDQPSVL
Rv0145|M.tuberculosis_H37Rv THFFDEYFGAAVDAGVRQVVILAAGLDARAYRLNWPAGTVVYEIDQPSVL
Mflv_0743|M.gilvum_PYR-GCK THFFDAFFSAAVDAGVRQIVILASGLDSRAFRLPWPAGTVVYEIDQPLVL
Mvan_0104|M.vanbaalenii_PYR-1 THFFDAFFAAAVDAGIRQIVILASGLDSRAFRLPWPAGTTVFEIDQPLVL
MMAR_0955|M.marinum_M TAFFDEFFLDATRAGIGQAVILAAGLDSRAWRLPWPAGTTVFELDQPRVL
MAV_4557|M.avium_104 TAFFDSFFLEATGAGIRQAVILAAGLDARSWRLPWPAGTTVYELDQPRVL
MAB_4584c|M.abscessus_ATCC_199 SKFFDEFFINATNSGCKQAVILAAGLDVRAHRLPWPAGTKVFELDQPQVL
MLBr_02020|M.leprae_Br4923 TRFFDDFFSSAGDTGIRQAVIVAAGLDSRAYRLKWPNGATVFEIDLPKVL
: :** * * * * **:*:* * *: ** ** : *:*:* * *:
TH_2706|M.thermoresistible__bu AFKTRTLAELGAPPTAPHRPVAVDLRDDWPAALTAAGFDPTVATAWSAEG
MUL_0818|M.ulcerans_Agy99 DFKSRTLADLGAAPTADRRVVAVDLREDWPAALRAAGFDPNQPTAWSAEG
MSMEG_1480|M.smegmatis_MC2_155 EFKTRTLADLGAQPTAERRTVAVDLRDDWPAALRDAGFDPAEPTAWIAEG
Mb0150|M.bovis_AF2122/97 EYKAGILQSHGAVPTARRHAVAVDLRDDWPAALIAAGFDGTQPTAWLAEG
Rv0145|M.tuberculosis_H37Rv EYKAGILQSHGAVPTARRHAVAVDLRDDWPAALIAAGFDGTQPTAWLAEG
Mflv_0743|M.gilvum_PYR-GCK DYKSSTLAAHGVAPTAERREVPIDLRQDWPAALVATGFDPARPTAWLAEG
Mvan_0104|M.vanbaalenii_PYR-1 AYKSSTLASHGVQPTADRREVPIDLRQDWPTALTHAGFDADQPTAWLAEG
MMAR_0955|M.marinum_M EFKAATLAEHGAEPACGRVAVAVDLRQDWPTALRQAGFDPSVPSVWSAEG
MAV_4557|M.avium_104 EFKESTLAEHGAQPACNRVAVPVDLRHDWPEALRQAGFDASAPSVWSAEG
MAB_4584c|M.abscessus_ATCC_199 EFKDRVLAEHDATPTSDRREIAVDLRDDWPAALLAAGFDPEVPTAWSAEG
MLBr_02020|M.leprae_Br4923 EFKARVLAEQGAIPNAGRSEVAADLRADWPRALKAAGFDPQRSSAWSVEG
:* * .. * . : :. *** *** ** :*** .:.* .**
TH_2706|M.thermoresistible__bu LLRYLPPDAQDRLFDHITDLSAPGSRLATEDHPGPGAG----LGEKADEL
MUL_0818|M.ulcerans_Agy99 LLGYLPPEAQDRLLDTVTELSAPGSRLAAECLSGVDPAEEEQIKERMQEV
MSMEG_1480|M.smegmatis_MC2_155 LLIYLPAEAQDRLLDNITALSAPGSRLATEHMDHRILAEG--AGKRIGEW
Mb0150|M.bovis_AF2122/97 LLPYLPGDAADRLFDMVTALSAPGSQVAVEAFTMNTKGNT----QRWNRM
Rv0145|M.tuberculosis_H37Rv LLPYLPGDAADRLFDMVTALSAPGSQVAVEAFTMNTKGNT----QRWNRM
Mflv_0743|M.gilvum_PYR-GCK LLMYLPADAQDRLFAQITELSAPGSQVAAESMGVHAP-------DRRERM
Mvan_0104|M.vanbaalenii_PYR-1 LLMYLPADAQDRLFAQITELSAPGSRVAAESMGIHAQ-------DRRERM
MMAR_0955|M.marinum_M LMPYLPAVAQDLLFERVQGLTVRASRIAVEALGPKFLDPQ-VRANRSARM
MAV_4557|M.avium_104 LMPYLPAAAQDLLFDRIQGLTVAGSRVAVEALGPKFLDPQ-ARAKRRERM
MAB_4584c|M.abscessus_ATCC_199 LIIYLPSAAQDLLFERVVALSAPGSQVAVEATRGRPD------IAKWGEM
MLBr_02020|M.leprae_Br4923 LLPYLTNDAQSALFTRIGELCAPGSRIAVGALGSRLDR------KQLAAL
*: **. * . *: : * . .*::*. :
TH_2706|M.thermoresistible__bu GRRWREHG-----FEVQLSELFHPG-ERTPVVDYLRGRGWDARARP-RAE
MUL_0818|M.ulcerans_Agy99 SARWRAHG-----FDVDMVGLVYFG-DRNEAVPYLSDRGWLLTSTP-LPE
MSMEG_1480|M.smegmatis_MC2_155 SRRVGSS--------LDIADLFYTG-ERNTAGDYLRGLGWQVTVRP-SKE
Mb0150|M.bovis_AF2122/97 RERLG--------LDIDVQALTYHEPDRSDAAQWLATHGWQVHSVS-NRE
Rv0145|M.tuberculosis_H37Rv RERLG--------LDIDVQALTYHEPDRSDAAQWLATHGWQVHSVS-NRE
Mflv_0743|M.gilvum_PYR-GCK RERFASIASQIDIEPMDITELTYEDPDRAEVAEWLAAHGWTAQAVP-SQD
Mvan_0104|M.vanbaalenii_PYR-1 RERFASITAQFDVEPMDITELTYEDPDRADVAQWLTAHGWRAEAVP-SQD
MMAR_0955|M.marinum_M ERIRAVMAHVEPQREIPRTDELWYFEEREDVGDWFRRHDWDVTVTP-SGE
MAV_4557|M.avium_104 DRIQALMARIDPDRAVPRTDELWYFEEREDVGEWFGRHGWDVRVTP-SDE
MAB_4584c|M.abscessus_ATCC_199 QKKYADEG--HPMSKVDITTLFYDE-ERADVAEWLAARGWKVQGSH-ALE
MLBr_02020|M.leprae_Br4923 EATHPGVN---ISGDVDFSALTYEP--KTDSAQWLAAHGWAVEPVRNTLE
: : :: .* :
TH_2706|M.thermoresistible__bu VFAGYG---REFPDSAALAAMRDSSAVTAVRPVVRAGMR
MUL_0818|M.ulcerans_Agy99 LRAANGLAPAAVDDDGPSVDMLYVSGTLYTTPRPDPAP-
MSMEG_1480|M.smegmatis_MC2_155 AYADHG-----FELPEEMAELSGDSGYLSAHLK------
Mb0150|M.bovis_AF2122/97 EMARLG-----RAIPQDLVDETVRTTLLRGRLVTPAQPA
Rv0145|M.tuberculosis_H37Rv EMARLG-----RAIPQDLVDETVRTTLLRGRLVTPAQPA
Mflv_0743|M.gilvum_PYR-GCK AMRRLD-----RYVEVADSDGQSFSTFTTGTKL------
Mvan_0104|M.vanbaalenii_PYR-1 EMRRLH-----RLVEIADGDDQSFSTFTTAVKR------
MMAR_0955|M.marinum_M LMAGYG-----RAAAAQVEDRVPTNLFVAAQRK------
MAV_4557|M.avium_104 LMAGYG-----RPAPAEVRDFVPGNLFVAAQRR------
MAB_4584c|M.abscessus_ATCC_199 LAAAYG--VEIPELPEDVVEVVKQGNYVTAVLPS-----
MLBr_02020|M.leprae_Br4923 LQTSYG---MTPPDVDVQMDSFMHSQYITATR-------