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VSAMRAAGQATHDRIMAAAKAEFTEHGLAGARLNRIAINANASKERLYSYFESKERLFEAVVAQWINDAP YQVPLSAEDVPGYVAGLFDNIIADPQGARLQRWIELEAPDGMFDNHLLRRIFQAKLDEVRRGQQCGLIDP AWDPKSLLMLLIDIAYSMAASGFSIDRIVGEPLSERTLADRRNAAAEAARRLVGIS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4389 | - | - | 100% (196) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3705 | - | 1e-24 | 37.84% (185) | TetR family regulatory protein |
| M. abscessus ATCC 19977 | MAB_4647 | - | 3e-06 | 34.62% (78) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0149 | - | 4e-05 | 35.59% (59) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4072 | - | 1e-05 | 38.33% (60) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0144 | - | 4e-05 | 35.59% (59) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 3e-05 | 30.85% (94) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_3952 | - | 2e-23 | 36.17% (188) | hypothetical protein MMAR_3952 |
| M. avium 104 | MAV_0082 | - | 2e-23 | 38.46% (182) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1305 | - | 6e-12 | 38.00% (100) | TetR family protein regulatory protein |
| M. thermoresistible (build 8) | TH_4015 | - | 3e-06 | 26.11% (180) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4487 | - | 7e-06 | 48.00% (50) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4046 | - | 1e-25 | 38.58% (197) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3952|M.marinum_M --------------------------------------------------
MAV_0082|M.avium_104 --------------------------------------------------
Mvan_4046|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4389|M.abscessus_ATCC_1997 --------------------------------------------------
Mb0149|M.bovis_AF2122/97 MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV
Rv0144|M.tuberculosis_H37Rv MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV
MSMEG_1305|M.smegmatis_MC2_155 --------------------------------------------------
TH_4015|M.thermoresistible__bu --------------------------------------------------
MLBr_00815|M.leprae_Br4923 -------------------------------------------------M
Mflv_4072|M.gilvum_PYR-GCK --------------------------------------------------
MUL_4487|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3952|M.marinum_M -------------------------------MRTTAELR-ETILTAARSE
MAV_0082|M.avium_104 -------------------------------MRTATELR-GEILQAAGAE
Mvan_4046|M.vanbaalenii_PYR-1 -------------------------------MRSTGELR-DAILVAARAE
MAB_4389|M.abscessus_ATCC_1997 ----------------------------MSAMRAAGQATHDRIMAAAKAE
Mb0149|M.bovis_AF2122/97 ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQV
Rv0144|M.tuberculosis_H37Rv ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQV
MSMEG_1305|M.smegmatis_MC2_155 -------------------------------MAWDTARTKQKLLDAAVHE
TH_4015|M.thermoresistible__bu VVPRRRVDNGSNEQGVASDATGGDRMNRPLPPTARGRRSRRALLDAAKEV
MLBr_00815|M.leprae_Br4923 NNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASDV
Mflv_4072|M.gilvum_PYR-GCK -----------MRHSLIMDAVSGPKSGESLTVRRQ-RATKARIAAAAAEA
MUL_4487|M.ulcerans_Agy99 ------------------------MGRTDWLAAHRSEVAADRILDAAERL
: .*
MMAR_3952|M.marinum_M FAQYGLAGARIDRIARTAEASKERLYAHFQDKEALFRSVVAADMEEFFAA
MAV_0082|M.avium_104 FAQYGLAGARIDRIARVAQASKERLYAHFRDKETLFREVVAAGNREFFSA
Mvan_4046|M.vanbaalenii_PYR-1 FAQYGLAGARIDRIAKAAAASKERLYAHFRDKETLFREVLAADGAEFFAA
MAB_4389|M.abscessus_ATCC_1997 FTEHGLAGARLNRIAINANASKERLYSYFESKERLFEAVVAQWINDAPYQ
Mb0149|M.bovis_AF2122/97 FSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVIVA
Rv0144|M.tuberculosis_H37Rv FSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVIVA
MSMEG_1305|M.smegmatis_MC2_155 FSEHGPLGARVDRVASRAGVNKERIYQYFGSKQNLFSAVLEQEMIKLAAA
TH_4015|M.thermoresistible__bu FARDGFADARITDIADAAGTAHGSFYRYFDSKEEIFIELLRELVEELRQP
MLBr_00815|M.leprae_Br4923 FVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVSS
Mflv_4072|M.gilvum_PYR-GCK VAAHGLAGATIEHIAAAAEVGRATFFRYFSAKEDAVVEGMAAHWLDAIAD
MUL_4487|M.ulcerans_Agy99 YTEHDPASIGMNEIARAAGCSRATLYRYFESREALRTAYVHRETLRLGRE
. . :* * : : :* : :
MMAR_3952|M.marinum_M VTLRPDAVPEFVG-------DIYDLACRRPEHLRMITWANLE--GLVLDP
MAV_0082|M.avium_104 VTLRPDAVPDFVG-------GIYDLAREHPEHHRMISWAQLE--GIALDE
Mvan_4046|M.vanbaalenii_PYR-1 VSLRPDSVPEFAG-------DIFDLSLSHPEHFRMINWGRLE--GVSLDP
MAB_4389|M.abscessus_ATCC_1997 VPLSAEDVPGYVA-------GLFDNIIADPQGARLQRWIELE--APDG-M
Mb0149|M.bovis_AF2122/97 GIERARREPTLMGRLAVVVDFAMEADAQYPASTAFLATTVLE--SQRHPE
Rv0144|M.tuberculosis_H37Rv GIERARREPTLMGRLAVVVDFAMEADAQYPASTAFLATTVLE--SQRHPE
MSMEG_1305|M.smegmatis_MC2_155 VPLTPELAHDLGEFSG----RIYDYHREYPHYLRLLLWEGLDRNPLDGNP
TH_4015|M.thermoresistible__bu VRTDAGTEPKNPYERILR-ANRTYLEAYRANRAIMIVWEQVASLNEHVEQ
MLBr_00815|M.leprae_Br4923 VQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDNITEPRVAAQ
Mflv_4072|M.gilvum_PYR-GCK AIAAQPPELAADA-------AVVAAFQDLGHGFEAVSDQVRELAVMTRSS
MUL_4487|M.ulcerans_Agy99 IMQQIGDIDDPRD----------QLITSITATLRMVRQRPALAAWFASTR
MMAR_3952|M.marinum_M PQVEGVESVQAR-------DVGVIEAAQAAGHVDPHWHPMDLLVLLFGVG
MAV_0082|M.avium_104 PHAEG-QPAFAQ-------HVAAIEAAQADGHVDGAWQPDDLLIVLFGIA
Mvan_4046|M.vanbaalenii_PYR-1 PAGDDGRTAPAE-------ALDAVRAAQRDGLVDTRWDPEELLILLFGLG
MAB_4389|M.abscessus_ATCC_1997 FDNHLLRRIFQA-------KLDEVRRGQQCGLIDPAWDPKSLLMLLIDIA
Mb0149|M.bovis_AF2122/97 LSRTENDAVRATREFLVWAVNDAIERGELAADVDVSSLAETLLVVLCGVG
Rv0144|M.tuberculosis_H37Rv LSRTENDAVRATREFLVWAVNDAIERGELAADVDVSSLAETLLVVLCGVG
MSMEG_1305|M.smegmatis_MC2_155 PAARDERAEHYAG------DRRVVALAQADKTLRDDVAPAYLLYVARSMA
TH_4015|M.thermoresistible__bu LRREYSDRFAARIER---AIIRWQEAGLADPAIDPRYAAAALSGMLSNFA
MLBr_00815|M.leprae_Br4923 VRVATESCIDAV--------FALISADSRLDPHRARMVAVGLVGISVDCA
Mflv_4072|M.gilvum_PYR-GCK PVFSAWTLQLYLR-------YEAAIADLVGIRMADPAPDDPRPRLLGALA
MUL_4487|M.ulcerans_Agy99 PPIGGELAGQSE------VIAGLAAAFLQSLGPEAPAAVERRARWTVRVI
MMAR_3952|M.marinum_M LAWAQSPHPDAVAT----DRAVIEGRRAAAVEAARRIVAPIRGIS-----
MAV_0082|M.avium_104 LAWANSPHPDAATN----DPDANARRRAAAVEAARRIIAPSK--------
Mvan_4046|M.vanbaalenii_PYR-1 LAWAHWPDPRSVTE----DAGQIAQRRAAAVEAASRIVAVADGAADGSDR
MAB_4389|M.abscessus_ATCC_1997 YSMAASGFSIDRIVGEPLSERTLADRRNAAAEAARRLVGIS---------
Mb0149|M.bovis_AF2122/97 FYIGFVGSYQRMAT-------ITDSFQQLLAGTLWRPPT-----------
Rv0144|M.tuberculosis_H37Rv FYIGFVGSYQRMAT-------ITDSFQQLLAGTLWRPPT-----------
MSMEG_1305|M.smegmatis_MC2_155 AWWLAVPAAIDLMLGTTVAGEGPDVRRKALVTLVNDAVRYRKS-------
TH_4015|M.thermoresistible__bu YRWSVQDADYDLDTAAEQLSLLWANALGVRVPAHHEPAHA----------
MLBr_00815|M.leprae_Br4923 RYWLDTNRPISKSD-------AVEGTVQFAWGGLSHVPLTRL--------
Mflv_4072|M.gilvum_PYR-GCK MASVRIALDDWLVHG-----GSLPERVRTALASLHVA-------------
MUL_4487|M.ulcerans_Agy99 VSLLMFPGQDEADER-----AMLEEFVAPVVTPFPTRR------------
MMAR_3952|M.marinum_M --------
MAV_0082|M.avium_104 --------
Mvan_4046|M.vanbaalenii_PYR-1 LATSPRSR
MAB_4389|M.abscessus_ATCC_1997 --------
Mb0149|M.bovis_AF2122/97 --------
Rv0144|M.tuberculosis_H37Rv --------
MSMEG_1305|M.smegmatis_MC2_155 --------
TH_4015|M.thermoresistible__bu --------
MLBr_00815|M.leprae_Br4923 --------
Mflv_4072|M.gilvum_PYR-GCK --------
MUL_4487|M.ulcerans_Agy99 --------