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AWDTARTKQKLLDAAVHEFSEHGPLGARVDRVASRAGVNKERIYQYFGSKQNLFSAVLEQEMIKLAAAVP LTPELAHDLGEFSGRIYDYHREYPHYLRLLLWEGLDRNPLDGNPPAARDERAEHYAGDRRVVALAQADKT LRDDVAPAYLLYVARSMAAWWLAVPAAIDLMLGTTVAGEGPDVRRKALVTLVNDAVRYRKS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1305 | - | - | 100% (202) | TetR family protein regulatory protein |
| M. smegmatis MC2 155 | MSMEG_3807 | - | 6e-08 | 32.19% (146) | TetR-type regulator |
| M. smegmatis MC2 155 | MSMEG_5424 | - | 9e-08 | 25.88% (170) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0244 | - | 3e-08 | 40.32% (62) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0414 | - | 1e-07 | 38.71% (62) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0238 | - | 3e-08 | 40.32% (62) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02568 | - | 4e-09 | 41.94% (62) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3705 | - | 6e-25 | 36.41% (195) | TetR family regulatory protein |
| M. marinum M | MMAR_3952 | - | 2e-17 | 34.57% (162) | hypothetical protein MMAR_3952 |
| M. avium 104 | MAV_0082 | - | 9e-17 | 34.62% (156) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2255 | - | 8e-08 | 38.82% (85) | TetR-family protein transcriptional regulator |
| M. ulcerans Agy99 | MUL_1163 | - | 1e-08 | 41.94% (62) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4046 | - | 8e-17 | 33.95% (162) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0244|M.bovis_AF2122/97 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLY
Rv0238|M.tuberculosis_H37Rv MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLY
MUL_1163|M.ulcerans_Agy99 MAGGTKRLPRAIREQQMLDAAVQMFSANGYHETSMDTIAAAAQISKPMLY
MLBr_02568|M.leprae_Br4923 MAGGAKRIPRAVREQQMLDAAVQMFSVNGYHKTSMDAIAAEAQISKPMLY
Mflv_0414|M.gilvum_PYR-GCK MAGGTKRLPRAVREQQMLDAAVEIFSVNGYHETSMDAIAAEAQISKPMLY
MMAR_3952|M.marinum_M ------MRTTAELRETILTAARSEFAQYGLAGARIDRIARTAEASKERLY
MAV_0082|M.avium_104 ------MRTATELRGEILQAAGAEFAQYGLAGARIDRIARVAQASKERLY
Mvan_4046|M.vanbaalenii_PYR-1 ------MRSTGELRDAILVAARAEFAQYGLAGARIDRIAKAAAASKERLY
MAB_3705|M.abscessus_ATCC_1997 -----MPPDASATKKRLLDAAYAEFAEHGLAGARVDRIGAAAEANKRLLY
MSMEG_1305|M.smegmatis_MC2_155 -----MAWDTARTKQKLLDAAVHEFSEHGPLGARVDRVASRAGVNKERIY
TH_2255|M.thermoresistible__bu -----MPERPDPARQAILDAAVVEFEQHGFRKVALEDVARRAGVSRTTIY
. :* ** * * . :: :. * .: :*
Mb0244|M.bovis_AF2122/97 LYYGSKEDLFGACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYI
Rv0238|M.tuberculosis_H37Rv LYYGSKEDLFGACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYI
MUL_1163|M.ulcerans_Agy99 LYYGSKEDLFGACLNREMSRFIDAVRADIDLSQSPKDLLRNAIVSFLRYI
MLBr_02568|M.leprae_Br4923 LYYGSKEDLFGACLNREMSRFIAMVRADIDFTQSPKDLLRNTIVSFLRYI
Mflv_0414|M.gilvum_PYR-GCK LYYGSKEELFGACLHRELTRFVDEVNSNIDFTAPPKELLRTAVLAFLNYI
MMAR_3952|M.marinum_M AHFQDKEALFRSVVAADMEEFFAAVTLRPD---AVPEFVGDIYDLACRRP
MAV_0082|M.avium_104 AHFRDKETLFREVVAAGNREFFSAVTLRPD---AVPDFVGGIYDLAREHP
Mvan_4046|M.vanbaalenii_PYR-1 AHFRDKETLFREVLAADGAEFFAAVSLRPD---SVPEFAGDIFDLSLSHP
MAB_3705|M.abscessus_ATCC_1997 VYYTNKETLFDIVVAHSIQQMSEAVPFTPE---DLPGYAGALFDHLIKHP
MSMEG_1305|M.smegmatis_MC2_155 QYFGSKQNLFSAVLEQEMIKLAAAVPLTPELAHDLGEFSGRIYDYHREYP
TH_2255|M.thermoresistible__bu RRFTNRDELVAAVVDRENAALFADIAAELKHSGPQGDYYVEAFTLAILKF
: .:: *. : : : .
Mb0244|M.bovis_AF2122/97 DANRASWIVMYTQATSSQAFAHTVREGREQIVQLVAELVRAGTRGPLTDA
Rv0238|M.tuberculosis_H37Rv DANRASWIVMYTQATSSQAFAHTVREGREQIVQLVAELVRAGTRGPLTDA
MUL_1163|M.ulcerans_Agy99 DQNQASWIVMYTQAVSSQAFAQTVREGREQIVELVAGMLRAGTRSPRSDA
MLBr_02568|M.leprae_Br4923 DANRASWIVMYIQAMSLPAFAQTVREARDQITELVAGLMRVGTRSSRPDH
Mflv_0414|M.gilvum_PYR-GCK DANRASWMVLYTQATSSQAFAHTVREGRERIIEIVGRLLRSGTRFPEPDT
MMAR_3952|M.marinum_M EHLRMITWANLEGLVLDPPQVEGVESVQARDVG----VIEAAQAAGHVDP
MAV_0082|M.avium_104 EHHRMISWAQLEGIALDEPHAEG-QPAFAQHVA----AIEAAQADGHVDG
Mvan_4046|M.vanbaalenii_PYR-1 EHFRMINWGRLEGVSLDPPAGDDGRTAPAEALD----AVRAAQRDGLVDT
MAB_3705|M.abscessus_ATCC_1997 EHLRLATWAQLERPAAGP-------AETSAYAA----KVAAIAQTGLSAG
MSMEG_1305|M.smegmatis_MC2_155 HYLRLLLWEGLDRNPLDGNPPAARDERAEHYAGDRR-VVALAQADKTLRD
TH_2255|M.thermoresistible__bu RRHRVLHRMITDEPGFILHLAQQHWGAAVERMAEALRVIFPAGFAERIGE
: :
Mb0244|M.bovis_AF2122/97 EIEMMAVALVGAGEAVATRLGIGDTDVDEAAEMMINLFWLGLKGAP---V
Rv0238|M.tuberculosis_H37Rv EIEMMAVALVGAGEAVATRLGIGDTDVDEAAEMMINLFWLGLKGAP---V
MUL_1163|M.ulcerans_Agy99 EIDMMAAALVGAGEAVANRLSAGDTDVDEAAEMMIDLLWRGLKGAP---S
MLBr_02568|M.leprae_Br4923 EYEIMAGALVGAGEAMATRLTTGDIAVDEAAELMINLFWHGLKGAP---A
Mflv_0414|M.gilvum_PYR-GCK DFDMMAVALVGAGEAIASRVSTGDADVHEASELMINLFWRGLKGSPSAAS
MMAR_3952|M.marinum_M HWHPMDLLVLLFGVGLAWAQSP-----HPDAVATDRAVIEGRRAAAVEAA
MAV_0082|M.avium_104 AWQPDDLLIVLFGIALAWANSP-----HPDAATNDPDANARRRAAAVEAA
Mvan_4046|M.vanbaalenii_PYR-1 RWDPEELLILLFGLGLAWAHWP-----DPRSVTEDAGQIAQRRAAAVEAA
MAB_3705|M.abscessus_ATCC_1997 DVEPADILALTLGLTTAWLGASPALRGLAASEPFSPERLATHRTALIAAV
MSMEG_1305|M.smegmatis_MC2_155 DVAPAYLLYVARSMAAWWLAVP-AAIDLMLGTTVAGEGPDVRRKALVTLV
TH_2255|M.thermoresistible__bu AAVIEFADTILRYAAMALLLPS----VQPLDTADDIRAFATRHFLPSLPA
: :
Mb0244|M.bovis_AF2122/97 DR-LETGH----------------
Rv0238|M.tuberculosis_H37Rv DR-LETGH----------------
MUL_1163|M.ulcerans_Agy99 DREIGSNFAAG-------------
MLBr_02568|M.leprae_Br4923 DRDFGPSIVAG-------------
Mflv_0414|M.gilvum_PYR-GCK DRDADATDATAVITS---------
MMAR_3952|M.marinum_M RRIVAPIRGIS-------------
MAV_0082|M.avium_104 RRIIAPSK----------------
Mvan_4046|M.vanbaalenii_PYR-1 SRIVAVADGAADGSDRLATSPRSR
MAB_3705|M.abscessus_ATCC_1997 EALVSAAAR---------------
MSMEG_1305|M.smegmatis_MC2_155 NDAVRYRKS---------------
TH_2255|M.thermoresistible__bu ALHTGSA-----------------