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VRTATELRGEILQAAGAEFAQYGLAGARIDRIARVAQASKERLYAHFRDKETLFREVVAAGNREFFSAVT LRPDAVPDFVGGIYDLAREHPEHHRMISWAQLEGIALDEPHAEGQPAFAQHVAAIEAAQADGHVDGAWQP DDLLIVLFGIALAWANSPHPDAATNDPDANARRRAAAVEAARRIIAPSK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0082 | - | - | 100% (189) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_1611 | - | 6e-06 | 42.86% (63) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_4506 | - | 5e-05 | 24.24% (165) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1047 | - | 3e-05 | 41.07% (56) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4672 | - | 2e-05 | 25.44% (169) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1019 | - | 3e-05 | 41.07% (56) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3705 | - | 3e-25 | 34.57% (188) | TetR family regulatory protein |
| M. marinum M | MMAR_3952 | - | 1e-67 | 69.15% (188) | hypothetical protein MMAR_3952 |
| M. smegmatis MC2 155 | MSMEG_1305 | - | 1e-16 | 34.62% (156) | TetR family protein regulatory protein |
| M. thermoresistible (build 8) | TH_4573 | - | 5e-06 | 30.77% (65) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_4837 | - | 2e-05 | 36.23% (69) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4046 | - | 3e-62 | 63.64% (187) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1047|M.bovis_AF2122/97 ------------------------------MTGTERRHQLIGIARSLFAE
Rv1019|M.tuberculosis_H37Rv ------------------------------MTGTERRHQLIGIARSLFAE
MAV_0082|M.avium_104 -----------------------------MRTATELRGEILQAAGAEFAQ
MMAR_3952|M.marinum_M -----------------------------MRTTAELRETILTAARSEFAQ
Mvan_4046|M.vanbaalenii_PYR-1 -----------------------------MRSTGELRDAILVAARAEFAQ
MAB_3705|M.abscessus_ATCC_1997 ----------------------------MPPDASATKKRLLDAAYAEFAE
MSMEG_1305|M.smegmatis_MC2_155 ----------------------------MAWDTARTKQKLLDAAVHEFSE
Mflv_4672|M.gilvum_PYR-GCK MSELAKTAPRRGGQPANGTGSSGAARRGNRLPRDERRGQLLAAASEVFVD
MUL_4837|M.ulcerans_Agy99 --------------------MGTETSTDGVESITDLDRTILDTAHAVFET
TH_4573|M.thermoresistible__bu ------------------MATQRATADVEEQHESDRRDQILEAANACFAQ
:: * *
Mb1047|M.bovis_AF2122/97 RGYDGTSIEEIAQRANVSKPVVYEHFGGKEGLYAVVVDREMSALLDGITS
Rv1019|M.tuberculosis_H37Rv RGYDGTSIEEIAQRANVSKPVVYEHFGGKEGLYAVVVDREMSALLDGITS
MAV_0082|M.avium_104 YGLAGARIDRIARVAQASKERLYAHFRDKETLFREVVAAGNREFFSAVTL
MMAR_3952|M.marinum_M YGLAGARIDRIARTAEASKERLYAHFQDKEALFRSVVAADMEEFFAAVTL
Mvan_4046|M.vanbaalenii_PYR-1 YGLAGARIDRIAKAAAASKERLYAHFRDKETLFREVLAADGAEFFAAVSL
MAB_3705|M.abscessus_ATCC_1997 HGLAGARVDRIGAAAEANKRLLYVYYTNKETLFDIVVAHSIQQMSEAVPF
MSMEG_1305|M.smegmatis_MC2_155 HGPLGARVDRVASRAGVNKERIYQYFGSKQNLFSAVLEQEMIKLAAAVPL
Mflv_4672|M.gilvum_PYR-GCK RGYHAAGMDEIADRAGVSKPVLYQHFSSKVELYLAVLQRHVDNLVSGVRQ
MUL_4837|M.ulcerans_Agy99 YGVRRANIEDVATRAGVSRSTIYRRFPTKDELFERVVRREAELFFAALNQ
TH_4573|M.thermoresistible__bu LGIHRTSVQDVARAANVSRGTVYRYFEDRTILIEAAIEYGAQKFYQEIAA
* : :: :. * ..: :* : : * .: : :
Mb1047|M.bovis_AF2122/97 SLTNNR-SRVRVERVALALLTYVEERTDGFRIMIRDSPASISSG----TY
Rv1019|M.tuberculosis_H37Rv SLTNNR-SRVRVERVALALLTYVEERTDGFRIMIRDSPASISSG----TY
MAV_0082|M.avium_104 RP-------DAVPDFVGGIYDLAREHPEHHRMISWAQLEGIALD---EPH
MMAR_3952|M.marinum_M RP-------DAVPEFVGDIYDLACRRPEHLRMITWANLEGLVLD---PPQ
Mvan_4046|M.vanbaalenii_PYR-1 RP-------DSVPEFAGDIFDLSLSHPEHFRMINWGRLEGVSLD---PPA
MAB_3705|M.abscessus_ATCC_1997 TP-------EDLPGYAGALFDHLIKHPEHLRLATWAQLER-------PAA
MSMEG_1305|M.smegmatis_MC2_155 TPE----LAHDLGEFSGRIYDYHREYPHYLRLLLWEGLDRNPLDGNPPAA
Mflv_4672|M.gilvum_PYR-GCK ALRTTTDNRQRVRAAVQAFFDFIEHDSQGYRLIFENDYVTEP-----QVA
MUL_4837|M.ulcerans_Agy99 ATN-----GHNPREAVIEAFTLGVRLIRDSPLYSRIAESEPELFG--MFS
TH_4573|M.thermoresistible__bu AMAKKSTLAEQLGAMAETHAKILLDHRTRNRLMTDDAELMRHMIA---DA
:
Mb1047|M.bovis_AF2122/97 SSLLNDAVSQVSSILAGDFARRGLDPDLAPLYAQALVGSVSMTAQWWLD-
Rv1019|M.tuberculosis_H37Rv SSLLNDAVSQVSSILAGDFARRGLDPDLAPLYAQALVGSVSMTAQWWLD-
MAV_0082|M.avium_104 AEG-QPAFAQHVAAIEAAQADGHVDGAWQPDDLLIVLFGIALAWANSPH-
MMAR_3952|M.marinum_M VEGVESVQARDVGVIEAAQAAGHVDPHWHPMDLLVLLFGVGLAWAQSPH-
Mvan_4046|M.vanbaalenii_PYR-1 GDDGRTAPAEALDAVRAAQRDGLVDTRWDPEELLILLFGLGLAWAHWPD-
MAB_3705|M.abscessus_ATCC_1997 G--PAETSAYAAKVAAIAQTGLSAGDVEPADILALTLGLTTAWLGASPA-
MSMEG_1305|M.smegmatis_MC2_155 RDERAEHYAGDRRVVALAQADKTLRDDVAPAYLLYVARSMAAWWLAVPA-
Mflv_4672|M.gilvum_PYR-GCK AQVKVATESCTDAVFDLISHDSGLEPHRARMIAVGLVSISVDSARYWLN-
MUL_4837|M.ulcerans_Agy99 RSHVFPIGQFADGIAHTLRRCGADAPDADLANIADILLRVAVGIIMFPT-
TH_4573|M.thermoresistible__bu DAAVRRTTEFLMPYVQQAKERGEVGSGVDVKAASEWLARIIYSFTTVNEG
Mb1047|M.bovis_AF2122/97 AREPKKE-VVAAHLVNLVWNGLTHLEADPRLQDE------------
Rv1019|M.tuberculosis_H37Rv AREPKKE-VVAAHLVNLVWNGLTHLEADPRLQDE------------
MAV_0082|M.avium_104 PDAATNDPDANARRRAAAVEAARRIIAPSK----------------
MMAR_3952|M.marinum_M PDAVATDRAVIEGRRAAAVEAARRIVAPIRGIS-------------
Mvan_4046|M.vanbaalenii_PYR-1 PRSVTEDAGQIAQRRAAAVEAASRIVAVADGAADGSDRLATSPRSR
MAB_3705|M.abscessus_ATCC_1997 LRGLAASEPFSPERLATHRTALIAAVEALVSAAAR-----------
MSMEG_1305|M.smegmatis_MC2_155 AIDLMLGTTVAGEGPDVRRKALVTLVNDAVRYRKS-----------
Mflv_4672|M.gilvum_PYR-GCK NERPIDKDDAVEGTVQFIWGGLSHVPLTRS----------------
MUL_4837|M.ulcerans_Agy99 ERLDTSDDAAVREYAARYLIPIITL---------------------
TH_4573|M.thermoresistible__bu LTFDMSKPATVRRYVERFAVNGLR----------------------