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TASKRACQGHGSAAESDRPQKLDGQLGVIGIVLMVIAAAAPLTVIGGDGLLAIASGPGPGAPLGFLIAGL LLMAFAVGFVTMTPFVSEAGAFFSYITKGLGERWGLGAAFVALVTYTAIQVGMYGYMGWALNDLVTSYGG PELPWWLWAIVTLGLVAYLGYRNIELSSKVLGIALVLEIAVVLVTDAAIVFQGGRDGISAYSFTPEAAAS GPLGIAILFAFAGFMGFEATAVFRDEARQPERTIPRATYLSVAIIGVFYAVSCWAVVEAWGPANVKDVVQ KSLDSGGNALLDTAEAYVGAVFRDIMQILLVTSLFACVLSFHNVIARYQFALANKGVLPAPVGRVHPTER SPHISSALQSITAVAFVVLVAAVGLDPMVQVFSSMAGISTVGMLMLLILTSVAVPLFFSRDDSARAGRVL TTYVAPIVATIGLSASVYLVLKNFTLVTDQSTVISTVLAALPIAALIYGLVQKKGVHRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4350c | - | - | 100% (480) | putative amino acid permease |
| M. abscessus ATCC 19977 | MAB_0950c | - | 2e-69 | 30.96% (491) | putative amino acid permease family protein |
| M. abscessus ATCC 19977 | MAB_4122 | - | 4e-21 | 25.55% (454) | putative amino acid permease |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2347c | rocE | 8e-19 | 25.93% (405) | cationic amino acid transport integral membrane protein RocE |
| M. gilvum PYR-GCK | Mflv_1244 | - | 8e-64 | 30.91% (427) | amino acid permease-associated region |
| M. tuberculosis H37Rv | Rv2320c | rocE | 8e-19 | 25.93% (405) | cationic amino acid transport integral membrane protein RocE |
| M. leprae Br4923 | MLBr_01974 | - | 5e-12 | 22.22% (405) | putative permease |
| M. marinum M | MMAR_0869 | - | 1e-21 | 23.88% (423) | amino acid permease |
| M. avium 104 | MAV_2087 | - | 3e-19 | 25.56% (403) | amino acid transporter |
| M. smegmatis MC2 155 | MSMEG_1508 | - | 1e-152 | 58.37% (454) | amino acid permease-associated region |
| M. thermoresistible (build 8) | TH_4382 | - | 4e-14 | 23.98% (417) | PUTATIVE amino acid permease-associated region |
| M. ulcerans Agy99 | MUL_1244 | rocE | 5e-21 | 25.56% (403) | cationic amino acid transport integral membrane protein RocE |
| M. vanbaalenii PYR-1 | Mvan_2078 | - | 5e-67 | 32.26% (468) | amino acid permease-associated region |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2347c|M.bovis_AF2122/97 --------------------------------------------------
Rv2320c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2087|M.avium_104 --------------------------------------------------
MUL_1244|M.ulcerans_Agy99 --------------------------------------------------
MAB_4350c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_1508|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1244|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2078|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0869|M.marinum_M --------------------------------------------------
TH_4382|M.thermoresistible__bu --------------------------------------------------
MLBr_01974|M.leprae_Br4923 MFLSADVSCIEIVDINCSELRNDRRIPPQLALFCTNAANKAESAVTSHGQ
Mb2347c|M.bovis_AF2122/97 ---------------------------MPTTSMSLRELMLRRRPVSGAPV
Rv2320c|M.tuberculosis_H37Rv ---------------------------MPTTSMSLRELMLRRRPVSGAPV
MAV_2087|M.avium_104 -------------------------------------------------M
MUL_1244|M.ulcerans_Agy99 ---------------------------MPATSIRLREQMLRRRPAGGAPV
MAB_4350c|M.abscessus_ATCC_199 -----------------------------------MTASKRACQGHGSAA
MSMEG_1508|M.smegmatis_MC2_155 -----------------------------------MSANAPTSDDQGDLR
Mflv_1244|M.gilvum_PYR-GCK -----------------------------------MTESAERTAPGQTTP
Mvan_2078|M.vanbaalenii_PYR-1 -----------------------------------------MSTDSAAVE
MMAR_0869|M.marinum_M -----------------------------------------------MAV
TH_4382|M.thermoresistible__bu ---------------------------------------------MSGTR
MLBr_01974|M.leprae_Br4923 LPIMANRRWAPHTRRQSGRATSTCSSLMRFSASESRAHSRFECYTLVRWS
Mb2347c|M.bovis_AF2122/97 ASGASGNLKRSFGTFQLTMFGVGATIGTGIFFVLAQAVPEAG--PGVIVS
Rv2320c|M.tuberculosis_H37Rv ASGASGNLKRSFGTFQLTMFGVGATIGTGIFFVLAQAVPEAG--PGVIVS
MAV_2087|M.avium_104 APGTADHLRRGIGTFQLTMFGVGSTIGTGIFFVMSQAVPEAG--PAVIVS
MUL_1244|M.ulcerans_Agy99 AEGAAGSLKRSFGTFELTMFGVGSTVGTGIFFVLAEAVPEAG--PAVIVS
MAB_4350c|M.abscessus_ATCC_199 ESDRPQKLDGQLGVIGIVLMVIAAAAPLTVIGGDGLLAIASGPGPGAPLG
MSMEG_1508|M.smegmatis_MC2_155 DE---QRLHGRLGPIGVVFMVVAAAAPLTVIGGNMPLGMGLGNGAGAPVG
Mflv_1244|M.gilvum_PYR-GCK TASVQRLKRNAVGTFGVIFMAVATAAPITAMVGNVPIAVGFGNGSHAPAG
Mvan_2078|M.vanbaalenii_PYR-1 TAAPAGLKKGAIGMVAVIFMAVANAAPITAMTGNVPIAVGFGNGLGAPAG
MMAR_0869|M.marinum_M TTGARSELQKALGQRSAVLFGLAYMTPIIVLGIFGVIAERSK--GASAGS
TH_4382|M.thermoresistible__bu TEQAQPELRRVLGPGLLLLFIVGDILGTGIYALVGDVAGEVG--GAAWLP
MLBr_01974|M.leprae_Br4923 IRGQGGRAISKLGFWSVVMLGINSIIGAGIFMTPGEVIKIAG--PFAPIA
.* :: :
Mb2347c|M.bovis_AF2122/97 FIIAGIAAGLAAICYAELASAVPISGSAYSYAYTTLGEAVAMVVAACLLL
Rv2320c|M.tuberculosis_H37Rv FIIAGIAAGLAAICYAELASAVPISGSAYSYAYTTLGEAVAMVVAACLLL
MAV_2087|M.avium_104 FLLAGVAAGLAAVCYAELASAVPVSGSSYSYAYTTLGEVVAMGVAACLLL
MUL_1244|M.ulcerans_Agy99 FIIAGVAAGLAAICCAELASAVPVSGSSYSYAYATLGEAVAMGVASCLLL
MAB_4350c|M.abscessus_ATCC_199 FLIAGLLLMAFAVGFVTMTPFVSEAGAFFSYITKGLGERWGLGAAFVALV
MSMEG_1508|M.smegmatis_MC2_155 FLIAALVLLLFSIGFVAMTPYVPEAGAFFSYVTLGLGRRLGSGIAAVALI
Mflv_1244|M.gilvum_PYR-GCK YLVATIVLGLFAIGYATMAKHITATGAFYGYISHGLGRVMGMASGLIITL
Mvan_2078|M.vanbaalenii_PYR-1 FLFATIALTLFALGYVAMARHITTTGAFYGFISHGLGQVWGMASGFLATF
MMAR_0869|M.marinum_M YLLATVAMLFTAQSYGVMARHFPVAGSAYTYVRKALDARVGFMVGWAVLL
TH_4382|M.thermoresistible__bu FLIAFLIATVTAFSYLELVTKYPQAAGAALYVHKAFGIQFVTFLVAFIVM
MLBr_01974|M.leprae_Br4923 YTLAGIFAAVLAIVFATAAKYVKTNGSSYAYTTAAFGHRIGIYVGVTHAI
: .* : : . .. : :. .
Mb2347c|M.bovis_AF2122/97 EYGVATAAVAVGWSGYVNKLLSNLFGFQMPHVLSAAPWDTHPG------W
Rv2320c|M.tuberculosis_H37Rv EYGVATAAVAVGWSGYVNKLLSNLFGFQMPHVLSAAPWDTHPG------W
MAV_2087|M.avium_104 EYGVATAAVSVNWSGYLNKLLSNVVGFQLPHALSAAPWDAQPG------Y
MUL_1244|M.ulcerans_Agy99 EYGVATAAVAVGLSGYVNKLLHNVFGFQLPQALSEAPWDERPGEA--AGY
MAB_4350c|M.abscessus_ATCC_199 TYTAIQVGMYGYMGWALNDLVTSYGGPELPWWLWAIVTLGLVA------Y
MSMEG_1508|M.smegmatis_MC2_155 AYTAIQVGIYGYIGWAIDDTVRFYGGPEIPWPVYSFATLAIVA------V
Mflv_1244|M.gilvum_PYR-GCK AYIVFEASLIGIFAFFFQNFLSSQLGITIHWLVPALLMLVLNS------I
Mvan_2078|M.vanbaalenii_PYR-1 AYVVFEGSLIGGCAYFANDGVNTIAGVDIPWLVFAVAAVVAIA------A
MMAR_0869|M.marinum_M DYLFLPLVIWLIGGSYLQDRFP-----TVPFWTWIVGFAALTT------V
TH_4382|M.thermoresistible__bu CSGITSASTASRFFAANLEVGLGQEWGRLGVAGVALLFMALLA------M
MLBr_01974|M.leprae_Br4923 TASIAWGVLASSFVSTLLRVAFPEKIWADNDELISVKTLTFLVFIAVLLA
Mb2347c|M.bovis_AF2122/97 VNLPAVILIGLCALLLIRGASESARVNAIMVLIKLGVLGMFMIIAFSAYS
Rv2320c|M.tuberculosis_H37Rv VNLPAVILIGLCALLLIRGASESARVNAIMVLIKLGVLGMFMIIAFSAYS
MAV_2087|M.avium_104 VNLPAVMLIGMCALLLIRGASESAKVNAIMVMVKLGVLVVFGILAFTAFD
MUL_1244|M.ulcerans_Agy99 LNLPAIILIGLCALLLIRGVSESAKVNAIMVLIKLGVLGMFVILALTAYD
MAB_4350c|M.abscessus_ATCC_199 LGYRNIELSSKVLGIALVLEIAVVLVTDAAIVFQGGRDG-----------
MSMEG_1508|M.smegmatis_MC2_155 LGYRHIELSAKVLGVALALEIGIVVLLDLVIVANPGPAG-----------
Mflv_1244|M.gilvum_PYR-GCK LTYFDVNLTAKVLGVFLITEIFMLALGAVAVAVKGGGPDGFAIAET--LN
Mvan_2078|M.vanbaalenii_PYR-1 LCHFHISLTAAILGVTLVSEVLILLALAFTVIFSGGGPDGFMLDKTVLLN
MMAR_0869|M.marinum_M LNLIGLKVADRANFILMTFQLLILAFFVALTIGYLVGDSRS---------
TH_4382|M.thermoresistible__bu VNLRGVGESVRLNVLLTIVEISGLLLVIFVGLWAFTGGGADVDFTR----
MLBr_01974|M.leprae_Br4923 INIFGNLVIRWANGISALGKIFALSVFIAGGLWTIITQHVNNYVTSRSAY
: :
Mb2347c|M.bovis_AF2122/97 ------ADHLKDFVPFGVAGIGSAAGTIFFSYIGLDAVSTAGDEVKDPQK
Rv2320c|M.tuberculosis_H37Rv ------ADHLKDFVPFGVAGIGSAAGTIFFSYIGLDAVSTAGDEVKDPQK
MAV_2087|M.avium_104 ------MHHLDDFAPFGVAGVGTAAGTIFFSYIGLDAVSTAGDEVTNPQK
MUL_1244|M.ulcerans_Agy99 ------TNHLKDFAPFGVAGVGAAAGTIFFSFIGLDAVSTAGEEVRNPQQ
MAB_4350c|M.abscessus_ATCC_199 -----ISAYSFTPEAAASGPLGIAILFAFAGFMGFEATAVFRDEARQPER
MSMEG_1508|M.smegmatis_MC2_155 -----LTLSSFTPGVFTDGVLGIAVLFALTGFIGFEATAVFRDEARDPER
Mflv_1244|M.gilvum_PYR-GCK ------PVGAFQPAAIAGASAGLGLFFAFWSWVGFESTAMYGEESKDPKR
Mvan_2078|M.vanbaalenii_PYR-1 NAFTSLPEGAFGTAAAAGSMA-IGLFFAFWSWVGFETTAVYGEESRNPKK
MMAR_0869|M.marinum_M -----LLSLTPFTGNGGFTAITAGAAVAAYSFLGFDAVSTLTEETHDAER
TH_4382|M.thermoresistible__bu -----VVAFETTTDKSVFLAVSAATSLAFFAMVGFEDSVNMAEETRDPVV
MLBr_01974|M.leprae_Br4923 QPTTYSLLGVTEIGKSTAASMTLATIVALYAFTGFESIANAAEEMNTPDR
. . *:: :* .
Mb2347c|M.bovis_AF2122/97 TMPRALIAALVVVTGVYVLVALAALG----TQPWQDFAEQETAGLAIILD
Rv2320c|M.tuberculosis_H37Rv TMPRALIAALVVVTGVYVLVALAALG----TQPWQDFAEQETAGLAIILD
MAV_2087|M.avium_104 TMPRALIAALLTVTGVYVFVALAALG----TQPWQDFGGQQEAGLATILD
MUL_1244|M.ulcerans_Agy99 SVPRALIAALFVVTGVYVLVAFAALG----TQPWQMFAGQEEAGLATILD
MAB_4350c|M.abscessus_ATCC_199 TIPRATYLSVAIIGVFYAVSCWAVVEAWGPANVKDVVQKSLDSGGNALLD
MSMEG_1508|M.smegmatis_MC2_155 TIPRATYAAVLIIGGFYALTCWAFVVAIGPDQVAEVAQRTLDGEANMLLD
Mflv_1244|M.gilvum_PYR-GCK IIPRATMIAVLGVGIFYVFVSWMAIAGTGPQQAVELAQS-ADTSSEIFFA
Mvan_2078|M.vanbaalenii_PYR-1 IIPRATLIAVIGLGLFYTFISAMVLAGNGAKASVEASIS-ASP-LDLFFN
MMAR_0869|M.marinum_M TIPRAIVLIALIGGAIFVTVAYVVSL--------VAPGSSFPDADSLSEG
TH_4382|M.thermoresistible__bu IFPRALLTGLGIAGAVYVVVAIVAVA-------LVPVGTLQASDVPLVEV
MLBr_01974|M.leprae_Br4923 TLPKAIPLTILTVGVIYILALVVAML----------LGSDKIVATNHTVK
.*:* .:
Mb2347c|M.bovis_AF2122/97 NVTH--GEWASTILAAGAVVSIFTVTLVTMYGQTRILFAMGRDG---LLP
Rv2320c|M.tuberculosis_H37Rv NVTH--GEWASTILAAGAVVSIFTVTLVTMYGQTRILFAMGRDG---LLP
MAV_2087|M.avium_104 HVTH--GSWASTILAAGAVISIFSVTLVTMYGITRILFAMGRDG---LLP
MUL_1244|M.ulcerans_Agy99 NVTH--SAWASTVLAMGAVISIFTVTLVTMYGQTRILFAMGRDG---LLP
MAB_4350c|M.abscessus_ATCC_199 TAEAYVGAVFRDIMQILLVTSLFACVLSFHNVIARYQFALANKG---VLP
MSMEG_1508|M.smegmatis_MC2_155 TTGDNLGRIGRDVVNVLLLTSLFACVLSFHNVIARYQFALARKG---LLP
Mflv_1244|M.gilvum_PYR-GCK PVRDTYGEWAITLFNILLVTGSFACGMAFHNCASRYLYALGREGLSTGLQ
Mvan_2078|M.vanbaalenii_PYR-1 LVDANLGGFLLDVYKILLVIGSFACALAFHNAASRYLFALGREIPSDKVK
MMAR_0869|M.marinum_M VARTIGGNLFAAVFLAALIIGQFTSGLAAQAAVSRLLYAMGRDG--VLPR
TH_4382|M.thermoresistible__bu VKAGAPGLPIEELLPWISMFAVSNTALINMLMASRLIYGMARQR---VLP
MLBr_01974|M.leprae_Br4923 LAAAVGNNTFRTIIVVGALVSMFGINVAASFGAPRLWTALSDGR---ILP
. : : . : .* .:.
Mb2347c|M.bovis_AF2122/97 ARFAKVNPRTMTPVHNTVIVAIFASTLAAFIP------------------
Rv2320c|M.tuberculosis_H37Rv ARFAKVNPRTMTPVHNTVIVAIFASTLAAFIP------------------
MAV_2087|M.avium_104 PRFARVNPRTMTPVNNTVIVAVAAATLAAFIP------------------
MUL_1244|M.ulcerans_Agy99 ARFAAVHPRFQTPVSNTVVVAIAAAVLAALVP------------------
MAB_4350c|M.abscessus_ATCC_199 APVGRVHPTERSPHISSALQSITAVAFVVLVA----------------AV
MSMEG_1508|M.smegmatis_MC2_155 KPLATVHPSHGSPSVSSLVQTATAAVIVAILA----------------AL
Mflv_1244|M.gilvum_PYR-GCK KTLGATHKTHGSPYIASFVQSGIALVLVLAFF----------------FA
Mvan_2078|M.vanbaalenii_PYR-1 STLGAAHPRHGSPYIASAVQALITMVIVLLFFGFTAVQVPDATGVPVDTP
MMAR_0869|M.marinum_M RVFGVVSAKFHTPMFNIMLTGAVGMAAILLSV------------------
TH_4382|M.thermoresistible__bu PVLGSVHPRRRTPWVAIIFTTLIAFGLIFYVT------------------
MLBr_01974|M.leprae_Br4923 TRLSSKN-RFGVPIVAFGITAFLTLAFPLSLR------------------
.. * .
Mb2347c|M.bovis_AF2122/97 --------LDSLADMVSIGTLTAFSVVAVGVIVLRVREPDLPRG---FKV
Rv2320c|M.tuberculosis_H37Rv --------LDSLADMVSIGTLTAFSVVAVGVIVLRVREPDLPRG---FKV
MAV_2087|M.avium_104 --------LQNLADMVSIGTLTAFVVVSVGVIVLRVREPDLPRG---FRV
MUL_1244|M.ulcerans_Agy99 --------LNRLADMVSIGTLTAFIVVSVGVIILRVREPALPRG---FWV
MAB_4350c|M.abscessus_ATCC_199 GLDPMVQVFSSMAGISTVGMLMLLILTSVAVPLFFSRDDSARAG-RVLTT
MSMEG_1508|M.smegmatis_MC2_155 GIDPLVGVFGSMAGVATVGMVLLMLTTSVAVLVFFARHADLASG-RVWQT
Mflv_1244|M.gilvum_PYR-GCK GMDPYIHMYTLLAILGTMAILIVQSLCAFSVVAYFHFHKNHPSSAHWFKT
Mvan_2078|M.vanbaalenii_PYR-1 SLVPYTNIYGLLALIGTAAILLVQAICSVAVVWYFWVRKTHRG--NVLTT
MMAR_0869|M.marinum_M ---------ATSTSFINFGAFTAFTLVNVSVVVYFVRERGAGLP-----R
TH_4382|M.thermoresistible__bu -AFADSTAIAVLGGTTSLLLLAVFAMVNVAVLVLRRDESRDPVVAR-RHF
MLBr_01974|M.leprae_Br4923 ------FDSLNLTGLAVIARFIQFIIVPIALFALARSRTTNSVY-VKRNV
. ..:
Mb2347c|M.bovis_AF2122/97 PGYPVTPVLSVLACGYILASLHWYTWLAFSGWVAVAVIFYLMWGRHHSAL
Rv2320c|M.tuberculosis_H37Rv PGYPVTPVLSVLACGYILASLHWYTWLAFSGWVAVAVIFYLMWGRHHSAL
MAV_2087|M.avium_104 PGYPVTPVLSIMACGYILASLHWYTWIAFSGWVLLALIFYFVWGRHHSAL
MUL_1244|M.ulcerans_Agy99 PGYPVTPILSILACGYLLYSLHWYTWIAFGGWVGIALIFYLFWGRHHSRL
MAB_4350c|M.abscessus_ATCC_199 YVAPIVATIGLSASVYLVLKNFTLVTDQST------VISTVLAALPIAAL
MSMEG_1508|M.smegmatis_MC2_155 RIAPVLACLGLVGALLLVLTNFTLVTGGSA------TVSAILAAVPFVGL
Mflv_1244|M.gilvum_PYR-GCK FLAPLTGGIGMLYVVYLLWEHKESAAGAASGTLLFKLTPWIVVGVFAFGA
Mvan_2078|M.vanbaalenii_PYR-1 LVCPVLGALAMGYVVWLLWDNRAFAAGYAANSLVFKNAPFFIAGVFLVGL
MMAR_0869|M.marinum_M WRYLVLPVIGAAVDIYLLAHLASDALIVGLSWAAIGFLYLLWLTRGLTRQ
TH_4382|M.thermoresistible__bu RTPTFLPVVGFVASLYLVTPLSGRPAQQYLLSVVLIVIGVLLFGVTMAIN
MLBr_01974|M.leprae_Br4923 FTDKVLPITAVVVSAGLMVSFDYRSIFLTRGGPNYFSISLIAITFIGIPA
. . :: .
Mb2347c|M.bovis_AF2122/97 NEEVP------------------------
Rv2320c|M.tuberculosis_H37Rv NEEVP------------------------
MAV_2087|M.avium_104 NDAAVD--PSGQER---------------
MUL_1244|M.ulcerans_Agy99 NAPALHDNPTGEER---------------
MAB_4350c|M.abscessus_ATCC_199 IYGLVQKKGVHRR----------------
MSMEG_1508|M.smegmatis_MC2_155 LAGAARRP---RD----------------
Mflv_1244|M.gilvum_PYR-GCK AMALYFKFKDKRRYELIGRIVYDDSEVRD
Mvan_2078|M.vanbaalenii_PYR-1 GYALWLRRARPEVYAEIGRTVMEDSHERS
MMAR_0869|M.marinum_M PPDLAGAAERG------------------
TH_4382|M.thermoresistible__bu RQLGIPTRAVGDPAKMVLPPD--------
MLBr_01974|M.leprae_Br4923 VAYLHYYRTSGIK----------------