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VTEFAVPTTTHSGPAVERDVVVIGAGISGLMTARRLVQAGHSVAVLEARDRVGGRTWSQIMDGEFFEIGG QWISSDQDALKDLLAELGKKTFRRYREGNSVYIGQDGERREFTGDFPVPEATLQQVNQLIHALDSLAAEI DAATPWQHPRAAELDAIPFATWLASNSDDKEARRIVGHYIAAGMFTKPSHSFSVLQAMLMIASAGKFEHL IDEGILLDERVVGGMQSVSQQIADELGPDVVHLSTRVRHLAWSDAGDGLPSIVSAVSDRVTVRARFAVLA IPPNLYSTIDYQPPLPRIQQVSHQHQSMGLVIKAQAVYETPFWRAHGLSGTGFASRERICEVYDNTVADH PHGTLVGFVAGEQAEETWALPDDQRRGAILESFAAYFGDEAKRPLAVYLSDWGTEEFTRGAYGASWSIGG LSRWGHLQNRPVGPIFFASSDIQGIGYMHVDGGVRIGTDTANRINSALLAPVNS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4321 | - | - | 100% (474) | putrescine oxidase |
| M. abscessus ATCC 19977 | MAB_2659 | - | 1e-47 | 27.41% (456) | putative flavin-containing monoamine oxidase AofH |
| M. abscessus ATCC 19977 | MAB_2294c | - | 2e-05 | 53.85% (39) | monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3195 | aofH | 5e-61 | 35.90% (454) | flavin-containing monoamine oxidase |
| M. gilvum PYR-GCK | Mflv_1230 | - | 8e-53 | 30.69% (466) | amine oxidase (flavin-containing) |
| M. tuberculosis H37Rv | Rv3170 | aofH | 5e-61 | 35.90% (454) | flavin-containing monoamine oxidase |
| M. leprae Br4923 | MLBr_00062 | gltD | 5e-05 | 48.65% (37) | glutamate synthase subunit beta |
| M. marinum M | MMAR_3362 | aofH_1 | 7e-64 | 33.63% (452) | flavin-containing monoamine oxidase AofH_1 |
| M. avium 104 | MAV_4062 | - | 4e-59 | 34.92% (461) | putative flavin-containing monoamine oxidase AofH |
| M. smegmatis MC2 155 | MSMEG_2035 | - | 6e-55 | 32.52% (452) | amine oxidase |
| M. thermoresistible (build 8) | TH_2921 | - | 6e-64 | 34.70% (464) | PUTATIVE putative flavin-containing monoamine oxidase AofH_1 |
| M. ulcerans Agy99 | MUL_1281 | aofH_1 | 1e-64 | 33.85% (452) | flavin-containing monoamine oxidase AofH_1 |
| M. vanbaalenii PYR-1 | Mvan_1178 | - | 1e-61 | 33.77% (453) | amine oxidase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3362|M.marinum_M --------------MAEVDVCVVGAGFAGLTAALRLKQAGHSVALLEARD
MUL_1281|M.ulcerans_Agy99 --------------MAEVDVCVVGAGFAGLTAALRLKQAGHSVALLEARD
Mvan_1178|M.vanbaalenii_PYR-1 --------------MVDLDYCVVGAGFAGLTAALRLKQAGHSVTLLEARD
Mb3195|M.bovis_AF2122/97 ----------MTNPPWTVDVVVVGAGFAGLAAARELTRQGHEVLVFEGRD
Rv3170|M.tuberculosis_H37Rv ----------MTNPPWTVDVVVVGAGFAGLAAARELTRQGHEVLVFEGRD
MAV_4062|M.avium_104 ----------MSGPPRIVDVVVVGAGFAGLAAARELNRQGHDVVVFEGRD
MSMEG_2035|M.smegmatis_MC2_155 ----------MSIPT-SADVVVVGAGFAGLTAARRLVQLGYDVVVLEGRD
Mflv_1230|M.gilvum_PYR-GCK ------------MARDEADVLIVGAGISGLIAARTVLAAGLTPLVVEADT
TH_2921|M.thermoresistible__bu -------------------VVVVGAGLAGLTAARTLRRAGVDVVVLEARD
MAB_4321|M.abscessus_ATCC_1997 MTEFAVPTTTHSGPAVERDVVVIGAGISGLMTARRLVQAGHSVAVLEARD
MLBr_00062|M.leprae_Br4923 -----MADPAGFLKYTQRELPRRRPVPLRLRDWKELYEEFDKETLRNQAS
. * : : :
MMAR_3362|M.marinum_M RVGGRTFTVVREDGS---------WIDKGGAWIGPTQ--HRIYALMKEFG
MUL_1281|M.ulcerans_Agy99 RVGGRTFTVVREDGS---------WIDKGGAWIGPTQ--HRIYALMKEFG
Mvan_1178|M.vanbaalenii_PYR-1 RIGGRTFTVNRDDGT---------WIDRGGAWIGPGQ--DRIDALMEEFG
Mb3195|M.bovis_AF2122/97 RVGGRSLTGRVAGVP----------ADMGGSFIGPTQ--DAVLALATELG
Rv3170|M.tuberculosis_H37Rv RVGGRSLTGRVAGVP----------ADMGGSFIGPTQ--DAVLALATELG
MAV_4062|M.avium_104 RVGGRSFTGSVAGLP----------ADLGGTFVGPTQ--DAVLALAAELE
MSMEG_2035|M.smegmatis_MC2_155 RVGGRSSTATIAGVP----------VDLGGTFVGPTQ--DAVLGLAAELG
Mflv_1230|M.gilvum_PYR-GCK RVGGRVLTEELAGLP----------MELGAQWIGDTH--HRMFALAAELG
TH_2921|M.thermoresistible__bu RVGGRTLNHFLEHGPD---PENDAVVELGGQWIGPGH--QRIRALIDELG
MAB_4321|M.abscessus_ATCC_1997 RVGGRTWSQIMDGEF----------FEIGGQWISSDQ--DALKDLLAELG
MLBr_00062|M.leprae_Br4923 RCMDCGIPFCHNGCPLGNLIPEWNDLVRRGRWHDAVERLHATNNFPDVTG
* . . : . . . :
MMAR_3362|M.marinum_M VAAFKQYTDGEAMMVVD---GKQYRYQGTIPRTLSPLASMNLGTAMFEIS
MUL_1281|M.ulcerans_Agy99 VAAFKQYTDGEAMMVVD---GKQYRYQGTIPRTLSPLASMNLGTAMFEIS
Mvan_1178|M.vanbaalenii_PYR-1 IPSYKQYVDGDAMMFID---GKTYRYHGTIPMSMSPFAVANLGVVFLELT
Mb3195|M.bovis_AF2122/97 IPTTPTHRDGRNVIQWR---GSARSYRGTIPK-LSLTGLIDIGRLRWQFE
Rv3170|M.tuberculosis_H37Rv IPTTPTHRDGRNVIQWR---GSARSYRGTIPK-LSLTGLIDIGRLRWQFE
MAV_4062|M.avium_104 VPTTPTHHEGKNLIHWR---GWTHAYHGTIPK-LSLTGLLDIGRLRWQFD
MSMEG_2035|M.smegmatis_MC2_155 CATVPTYNRGKNLIRWH---GRVRSYRSTIPR-LSIIELLDVSRIQWRFE
Mflv_1230|M.gilvum_PYR-GCK VETYPQYDDGETSYELA---GTGVLRGNDFHE-RFAGELAELEKVLRRLD
TH_2921|M.thermoresistible__bu LSTFDTYDRGAKLWEHN---GRVRRYTGEIPR-ANPLHLADLQIALTRLE
MAB_4321|M.abscessus_ATCC_1997 KKTFRRYREGNSVYIGQD--GERREFTGDFPV--PEATLQQVNQLIHALD
MLBr_00062|M.leprae_Br4923 RLCPAPCESACVLGINQDPVTIKQIELEIIDKAFDEGWVQPLPPQQLTGK
. : :
MMAR_3362|M.marinum_M QMCKTIPLEAPWEAKRAAKWDRMTLAQWLRNNVKSKAAHD-LLETAIAG-
MUL_1281|M.ulcerans_Agy99 QMCKTIPLEAPWEAKRAAKWDRMTLAQWLRNNVKSKAAHD-LLETAIAG-
Mvan_1178|M.vanbaalenii_PYR-1 RMCKSIPPEAPWTAPKAHKWDQVTWAKWLDGNTLSTPARQ-LLESAVSG-
Mb3195|M.bovis_AF2122/97 RIARGVPVAAPWDARRARELDDVSLGEWLRLVRATSSSRN-LMAIMTRV-
Rv3170|M.tuberculosis_H37Rv RIARGVPVAAPWDARRARELDDVSLGEWLRLVRATSSSRN-LMAIMTRV-
MAV_4062|M.avium_104 RIARSIPLAAPWEARRAAELDGLSLGGWLRSVRATASSHA-LLAMVARV-
MSMEG_2035|M.smegmatis_MC2_155 RLFRHVDVAEPWNGSLAHKLDQYSMERWLRYVHANASTRN-LMAIMSRV-
Mflv_1230|M.gilvum_PYR-GCK ELAAEVCAATPWTAPHAAEWDAITAGAWYDAQGLSPVART-LLEICTVG-
TH_2921|M.thermoresistible__bu RMARRIDPAAPWAAPRAAQWDRQTVAGWIDRHVRTAVGRA-FIELVCEA-
MAB_4321|M.abscessus_ATCC_1997 SLAAEIDAATPWQHPRAAELDAIPFATWLASNSDDKEARR-IVGHYIAAG
MLBr_00062|M.leprae_Br4923 TVAVVGSGPAGLAAAQQLTRAGHRVTVFERDDRIGGLLRYGIPEFKMEKR
: : : :
MMAR_3362|M.marinum_M CYTSDASEVSMLFVLYQMASGGGPGFVLG-SKGAAQDARPIGGMGAVYGP
MUL_1281|M.ulcerans_Agy99 CYTSDASEVSMLFVLYQMASGGGPGFVLG-SKGAAQDARPIGGMGAVYGP
Mvan_1178|M.vanbaalenii_PYR-1 LYTSAASELSLLFCLYQMAAAGGPSFVLG-VKDAAEDARPVGGMGAIHRA
Mb3195|M.bovis_AF2122/97 TWGCEPDDVSMLHAARYVRAAGGLDRLLD-VKNGAQQDRVPGGTQQIAQA
Rv3170|M.tuberculosis_H37Rv TWGCEPDDVSMLHAARYVRAAGGLDRLLD-VKNGAQQDRVPGGTQQIAQA
MAV_4062|M.avium_104 TWGCEPDEVSMLHAARYAHAAGGLDRLLD-VEDGAQQDRFPGGTQQIAAA
MSMEG_2035|M.smegmatis_MC2_155 TWGAEPDQVSMLHAVRYVKAAGGLTRLLD-VEGGAQQDRLVEGTQQIALR
Mflv_1230|M.gilvum_PYR-GCK ILAVPTVEVSFLHLLFTIQTCGVTAELFAESEGGAQTTRFVGGTAEIPKR
TH_2921|M.thermoresistible__bu VWAADAADLSLLHLLTYTSSNQGLSQLIT-TRGGAQQSRIIGGAQQISTA
MAB_4321|M.abscessus_ATCC_1997 MFTKPSHSFSVLQAMLMIASAGKFEHLID--EGILLDERVVGGMQSVSQQ
MLBr_00062|M.leprae_Br4923 FLERRLDQLRAEGTEFRSGVNVGVDITADQLCADFDAVVLAGGAATWREL
.. *
MMAR_3362|M.marinum_M MAAELG-DAIHLSQPVRSITQDSGG------VTVQAEGLTVRANRTIVAV
MUL_1281|M.ulcerans_Agy99 MAAELG-DAIHLSQPVRSITQDSGG------VTVQAEGLTVRANRTIVAV
Mvan_1178|M.vanbaalenii_PYR-1 VAAELG-DVVQLSQPVRSIAQDAEG------VTVRSEDRVVRARRAIVTV
Mb3195|M.bovis_AF2122/97 AAAQLG-ARVLLNAAVRRIDRHGAG------VTVTSDQGQAEAGFVIVAI
Rv3170|M.tuberculosis_H37Rv AAAQLG-ARVLLNAAVRRIDRHGAG------VTVTSDQGQAEAGFVIVAI
MAV_4062|M.avium_104 AAAELG-ARVVLGAPVRRIERHGAG------VTVRTDLGDTEAGFVIVAI
MSMEG_2035|M.smegmatis_MC2_155 MADELG-QRIALDAPVQRIERHSGGD-----IGVTFTTGHVRARAVVIAI
Mflv_1230|M.gilvum_PYR-GCK LAALIS-EHIVLDSPVQLIEHRADSV-----TLHCRGGRTAQGRRVIVAV
TH_2921|M.thermoresistible__bu MADELG-DAVRLGAPVREIRTRDG-------VQVVADTATVRAERVVVAM
MAB_4321|M.abscessus_ATCC_1997 IADELGPDVVHLSTRVRHLAWSDAGDGLPSIVSAVSDRVTVRARFAVLAI
MLBr_00062|M.leprae_Br4923 PIPGRELDGVHQAMEFLPWVNRVQEG---DDVLGDDGQPPITAKDKKVVI
: . . :.:
MMAR_3362|M.marinum_M P------LAIASQIVYEPMLPTDRSFLHQRMPSGAVVKISAVYDEPFWRA
MUL_1281|M.ulcerans_Agy99 P------LAIASQIVYEPMLPTDRSFLHQRMPSGAVVKISAVYDEPFWRA
Mvan_1178|M.vanbaalenii_PYR-1 P------IAIASHILYEPMLPVDRSFLHQRMPSGAVFKIAMVFDEPFWRA
Mb3195|M.bovis_AF2122/97 P------PAHRVAIEFDPPLPPEYQQLAHHWPQGRLSKAYAAYSTPFWRA
Rv3170|M.tuberculosis_H37Rv P------PAHRVAIEFDPPLPPEYQQLAHHWPQGRLSKAYAAYSTPFWRA
MAV_4062|M.avium_104 P------PAHRAAIEFAPPLPAEYEQLARHWPQGRLSKAYAAYSTPFWRA
MSMEG_2035|M.smegmatis_MC2_155 A------PQHRGDIEFDPPLPPEYTELAARWPQGRLSKAYAAYDRPFWRA
Mflv_1230|M.gilvum_PYR-GCK S------PTLAGRIMYDPPLSGYRDQLTQRMPNSAAMKAFFVYDEPFWRA
TH_2921|M.thermoresistible__bu S------PTLAGRLHYDEPLPADRDQLTQRMPNGSVVKCMAIYDEPFWRA
MAB_4321|M.abscessus_ATCC_1997 P------PNLYSTIDYQPPLPRIQQVSHQHQSMGLVIKAQAVYETPFWRA
MLBr_00062|M.leprae_Br4923 IGGGDTGADCLGAVHRQGAIHVHQLEIMPRPPDARAASTPWPTYPLMYRV
: : : . . . ::*.
MMAR_3362|M.marinum_M DGLCGQSAAPTSLATLTIDASPNSGTPGVLCVVIEGPVARQYERLDDDGR
MUL_1281|M.ulcerans_Agy99 DGLCGQSAAPTSLATLTIDASPNSGTPGVLCVVIEGPVARQYERLDDDGR
Mvan_1178|M.vanbaalenii_PYR-1 DGLSGQSFAPGSAANLTIDSCTDTGSPGILTAITEGLEARELCKLSDADR
Mb3195|M.bovis_AF2122/97 SGYSGQALSDEAPVFITFDVSPHADGPGILMGFVD---ARGFDSLPIEER
Rv3170|M.tuberculosis_H37Rv SGYSGQALSDEAPVFITFDVSPHADGPGILMGFVD---ARGFDSLPIEER
MAV_4062|M.avium_104 DGFSGQALSDEGPVFITFDVSPHPDGPGILMGFVD---ARAFDSLPADQR
MSMEG_2035|M.smegmatis_MC2_155 NGCSGEALSDEGPVFITFDVSPGDEGPGILLGFTD---ARTFDALPPEQR
Mflv_1230|M.gilvum_PYR-GCK DGLNGQLISDIGPARMSNDTCIQGDDHGVILLFLEGEQARTHGHWSEEER
TH_2921|M.thermoresistible__bu DGLSGQGVGFTGPVKVFFDNSPPSGRPGVLLGFLEGSQARELGRADTRTR
MAB_4321|M.abscessus_ATCC_1997 HGLSGTGFASRERICEVYDNTVADHPHGTLVGFVAGEQAEETWALPDDQR
MLBr_00062|M.leprae_Br4923 SPAHEEGGERVFSVNTEEFVGKNGRVHALKAHEVTMQDGRFVKVENSVFE
. .. .
MMAR_3362|M.marinum_M RQAVLAALVE-RFGAKAAKPIDYFEQNWSRE-RYSGGGMLSHTPPGVLTQ
MUL_1281|M.ulcerans_Agy99 RQAVLAALVE-RFGAKAAKPIDYFEQNWSRE-RYSGGGMLSHTPPGVLTQ
Mvan_1178|M.vanbaalenii_PYR-1 RKAVLAAVAE-RFGDKALSPLDYIEHNWTVE-RYSGGGMIAHTPPGVLTE
Mb3195|M.bovis_AF2122/97 RRDALRCFAS-LFGDEALDPLDYVDYRWGTE-EFAPGGPTAAVPPGSWTK
Rv3170|M.tuberculosis_H37Rv RRDALRCFAS-LFGDEALDPLDYVDYRWGTE-EFAPGGPTAAVPPGSWTK
MAV_4062|M.avium_104 RRDALRCFAT-LFGDDALKPLDYVDHRWGAE-EFAPGGPTAAVPPGSWTR
MSMEG_2035|M.smegmatis_MC2_155 RQRALGGFAT-FFGDAARDPIDYLDHCWGTE-AFAPGGPTAAVPPEAWTA
Mflv_1230|M.gilvum_PYR-GCK REALTAELVR-HFGDRAARPSHYIDGEWGSR-QWTRGCYNANCGPLVWTT
TH_2921|M.thermoresistible__bu REAVIGCFAR-MFGPRAARPVDYVEKVWAAD-QWTRGCYGAFLPPNTWTQ
MAB_4321|M.abscessus_ATCC_1997 RGAILESFAA-YFGDEAKRPLAVYLSDWGTE-EFTRGAYGASWSIGGLSR
MLBr_00062|M.leprae_Br4923 LEADLVLLAMGFVGPEKPGLLTDLGVKFTDRGNVARGADFDTSVPGVFVA
.. .* : : *
MMAR_3362|M.marinum_M FGHALRRPCGRIHWAGTETSAKMCGWIDGAIRSGERAASEVMANQTMTMA
MUL_1281|M.ulcerans_Agy99 FGHALRRPCGRIHWAGTEISAKMCGWIDGAIRSGERAASEVMANQTMTMA
Mvan_1178|M.vanbaalenii_PYR-1 YGPALRRPCGRIHWAGTESSALMYGFIDGAVRSGERAAAEVVEHEAMATS
Mb3195|M.bovis_AF2122/97 YGHWLREPVGPIHWASTETADEWTGYFDGAVRSGQRAAAEVAALL-----
Rv3170|M.tuberculosis_H37Rv YGHWLREPVGPIHWASTETADEWTGYFDGAVRSGQRAAAEVAALL-----
MAV_4062|M.avium_104 FGRWLREPVGPIHWAGTETADEWTGFLDGAIRSGRRAAAEVTALL-----
MSMEG_2035|M.smegmatis_MC2_155 YGPWLRKPIDGIHWAGTETADVWTGFLDGAVRSGQRAATEVAEALKSSAA
Mflv_1230|M.gilvum_PYR-GCK YGAALAEPIGVIHWASTDTAVEWSAYMEGAVEAGERAAREVIDALVSQRD
TH_2921|M.thermoresistible__bu VGPALRRAVGPIHWAGAETAVRSMGYMDGAVASGERAAAEVLTALGSGA-
MAB_4321|M.abscessus_ATCC_1997 WGHLQNRPVGPIFFASSDIQGIGYMHVDGGVRIGTDTANRINSALLAPVN
MLBr_00062|M.leprae_Br4923 G--DMGRGQSLIVWAIAEGRAAAAAVDRFLMGATALPAPVKPSSLPLQ--
. . * :* :: : .*
MMAR_3362|M.marinum_M SDS
MUL_1281|M.ulcerans_Agy99 SDS
Mvan_1178|M.vanbaalenii_PYR-1 ---
Mb3195|M.bovis_AF2122/97 ---
Rv3170|M.tuberculosis_H37Rv ---
MAV_4062|M.avium_104 ---
MSMEG_2035|M.smegmatis_MC2_155 AG-
Mflv_1230|M.gilvum_PYR-GCK R--
TH_2921|M.thermoresistible__bu ---
MAB_4321|M.abscessus_ATCC_1997 S--
MLBr_00062|M.leprae_Br4923 ---