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MSRSVDNAVEAASVDVVIVGAGFAGLSAADRLVNMGVSVLVIDARERVGGRSFTGEVAGVKVDLGATWVA KRHTAIRDLMDRLGCSLTPQYDEGVNLLWMAGKRKTWTGTLPTVDPVDLEDLGRITIEMGKLLETINVDA AWKSPNADQLDSISFGEWLSQQQAVTSTNALMYIVTRVQWGCSPLDVSLLHVLRYVQAVGGLDHMLAVEH GQQEYRVTETTQEIAKRLAAQIGDQIVLNTRVRQISQDDNGVTVSTDSGVINAKYAIVTAAPEHRAYIEY QPALPAKIEGLTTSFPMGALSKAFVAYDKPFWRAEGLSGEALTDTAPVFITFDVSPSDDGPGILMVFCTA RVYDGFGPEVRRKLVLKQLVDLYGEQANTPIDYIDHCWGTEPFAAGGPHPAAPPFASVNYGEALREPHGR IHWAGTETAGEWVGTMNGAILMGLHTADQIAQQLGVTGEVSK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2659 | - | - | 100% (462) | putative flavin-containing monoamine oxidase AofH |
| M. abscessus ATCC 19977 | MAB_4321 | - | 9e-48 | 27.41% (456) | putrescine oxidase |
| M. abscessus ATCC 19977 | MAB_0074c | - | 2e-07 | 50.00% (52) | putative (cyclohexanone) monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3195 | aofH | 1e-117 | 47.74% (442) | flavin-containing monoamine oxidase |
| M. gilvum PYR-GCK | Mflv_4501 | - | 1e-113 | 47.39% (441) | amine oxidase |
| M. tuberculosis H37Rv | Rv3170 | aofH | 1e-117 | 47.74% (442) | flavin-containing monoamine oxidase |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_1389 | aofH | 1e-115 | 46.26% (441) | flavin-containing monoamine oxidase AofH (amine oxidase) |
| M. avium 104 | MAV_4062 | - | 1e-115 | 47.85% (441) | putative flavin-containing monoamine oxidase AofH |
| M. smegmatis MC2 155 | MSMEG_2035 | - | 1e-115 | 46.73% (443) | amine oxidase |
| M. thermoresistible (build 8) | TH_0685 | - | 1e-112 | 46.46% (452) | PROBABLE FLAVIN-CONTAINING MONOAMINE OXIDASE AOFH (AMINE |
| M. ulcerans Agy99 | MUL_2487 | aofH | 1e-112 | 45.58% (441) | flavin-containing monoamine oxidase AofH (amine oxidase) |
| M. vanbaalenii PYR-1 | Mvan_1866 | - | 1e-115 | 47.39% (441) | amine oxidase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4501|M.gilvum_PYR-GCK ------------MAEVVVVGAGFAGLAAARELSRLGRDVVVVEGRDRVGG
Mvan_1866|M.vanbaalenii_PYR-1 ------------MADVVVVGAGFAGLSAARELTRLGHEVVVVEGRDRVGG
TH_0685|M.thermoresistible__bu ------------VVDVVVVGAGFAGLTAARELTGLGYEVVVFEGRDRVGG
MSMEG_2035|M.smegmatis_MC2_155 -------MSIPTSADVVVVGAGFAGLTAARRLVQLGYDVVVLEGRDRVGG
Mb3195|M.bovis_AF2122/97 ------MTNPPWTVDVVVVGAGFAGLAAARELTRQGHEVLVFEGRDRVGG
Rv3170|M.tuberculosis_H37Rv ------MTNPPWTVDVVVVGAGFAGLAAARELTRQGHEVLVFEGRDRVGG
MMAR_1389|M.marinum_M ------MTNPSWIVDVVIVGAGFAGLAAARDLARQGHDVLVLEGRDRVGG
MUL_2487|M.ulcerans_Agy99 ------MTNPSWIVDVVIVGAGFAGLAAARDLARQGHDVLVLEGRDRVGG
MAV_4062|M.avium_104 ------MSGPPRIVDVVVVGAGFAGLAAARELNRQGHDVVVFEGRDRVGG
MAB_2659|M.abscessus_ATCC_1997 MSRSVDNAVEAASVDVVIVGAGFAGLSAADRLVNMGVSVLVIDARERVGG
.:**:********:** * * .*:*.:.*:****
Mflv_4501|M.gilvum_PYR-GCK RSYTGSVGGVPVDFGATFVGPTQDAVLALAAELGVESVPTYGEGKNLIRW
Mvan_1866|M.vanbaalenii_PYR-1 RSYTGTIAGVPVDLGATFVGPTQDAVLKLADELGCEREPTFGRGKNLIRW
TH_0685|M.thermoresistible__bu RSYTATLAGVPVDLGATFVGPGQTAVTGLAAELGCPTVGTYHQGNNLILW
MSMEG_2035|M.smegmatis_MC2_155 RSSTATIAGVPVDLGGTFVGPTQDAVLGLAAELGCATVPTYNRGKNLIRW
Mb3195|M.bovis_AF2122/97 RSLTGRVAGVPADMGGSFIGPTQDAVLALATELGIPTTPTHRDGRNVIQW
Rv3170|M.tuberculosis_H37Rv RSLTGRVAGVPADMGGSFIGPTQDAVLALATELGIPTTPTHRDGRNVIQW
MMAR_1389|M.marinum_M RSFTGSIAGLPADMGGSFVGPTQDAVLALAAELGVPTVPTFHDGKNVIRW
MUL_2487|M.ulcerans_Agy99 RSFTGSIAGLPADMGGSFVGPSQDAVLALAAELGVPTVPTFHDGKNVIRW
MAV_4062|M.avium_104 RSFTGSVAGLPADLGGTFVGPTQDAVLALAAELEVPTTPTHHEGKNLIHW
MAB_2659|M.abscessus_ATCC_1997 RSFTGEVAGVKVDLGATWVAKRHTAIRDLMDRLGCSLTPQYDEGVNLLWM
** *. :.*: .*:*.:::. : *: * .* . * *::
Mflv_4501|M.gilvum_PYR-GCK RGRVRSYRSTIPRLSILELLDVSRIQWRFDRISKRVPVDQPWASPLAGQL
Mvan_1866|M.vanbaalenii_PYR-1 RGSVRSYRSTVPRLSIIELLDVSRIQWRFERVCRKVSVDQPWRSPVAAEL
TH_0685|M.thermoresistible__bu RGRLKSYRSTIPTLSILELLDVSRIQWRFERLCRQIPVGEPWRAPAAHRL
MSMEG_2035|M.smegmatis_MC2_155 HGRVRSYRSTIPRLSIIELLDVSRIQWRFERLFRHVDVAEPWNGSLAHKL
Mb3195|M.bovis_AF2122/97 RGSARSYRGTIPKLSLTGLIDIGRLRWQFERIARGVPVAAPWDARRAREL
Rv3170|M.tuberculosis_H37Rv RGSARSYRGTIPKLSLTGLIDIGRLRWQFERIARGVPVAAPWDARRAREL
MMAR_1389|M.marinum_M RGGVRPYSGTIPRLSLTGLLDIARLRWQFERLARSIPISAPWAANRAADL
MUL_2487|M.ulcerans_Agy99 RGGVRPYSGTIPRLSLTGLLDIARLRWQFERLARSIPISAPWAANRAADL
MAV_4062|M.avium_104 RGWTHAYHGTIPKLSLTGLLDIGRLRWQFDRIARSIPLAAPWEARRAAEL
MAB_2659|M.abscessus_ATCC_1997 AGKRKTWTGTLPTVDPVDLEDLGRITIEMGKLLETINVDAAWKSPNADQL
* :.: .*:* :. * *:.*: .: :: . : : .* . * *
Mflv_4501|M.gilvum_PYR-GCK DDISLDAWLRSVHAGASTRDLMAIMARVTWGAEPGDVSMLHAVRYVNAAG
Mvan_1866|M.vanbaalenii_PYR-1 DAVSLDGWLRSVHAGASTRDLMAIVARVTWGAEPDAVSMLHAVRYVKAAG
TH_0685|M.thermoresistible__bu DTMSLDRWLRSVYASASTRDLMAIMARVTWGCEPHQVSMLHAARYVKAAG
MSMEG_2035|M.smegmatis_MC2_155 DQYSMERWLRYVHANASTRNLMAIMSRVTWGAEPDQVSMLHAVRYVKAAG
Mb3195|M.bovis_AF2122/97 DDVSLGEWLRLVRATSSSRNLMAIMTRVTWGCEPDDVSMLHAARYVRAAG
Rv3170|M.tuberculosis_H37Rv DDVSLGEWLRLVRATSSSRNLMAIMTRVTWGCEPDDVSMLHAARYVRAAG
MMAR_1389|M.marinum_M DGVSLRQWLRSVRASASSHDLMAIMTRVTWGCEPDDVSMLHAARYVRAAG
MUL_2487|M.ulcerans_Agy99 DGVSLRQWLRSVRASASSHDLMAIMTRVTWECEPDDVSMLHAARSVRAAG
MAV_4062|M.avium_104 DGLSLGGWLRSVRATASSHALLAMVARVTWGCEPDEVSMLHAARYAHAAG
MAB_2659|M.abscessus_ATCC_1997 DSISFGEWLSQQQAVTSTNALMYIVTRVQWGCSPLDVSLLHVLRYVQAVG
* *: ** * :*:. *: :::** * ..* **:**. * ..*.*
Mflv_4501|M.gilvum_PYR-GCK GLNRMLDVEGGAQQDRFPAGTQKIADLMAAELG-----DRVVVGAPVRRI
Mvan_1866|M.vanbaalenii_PYR-1 GLSRMLDVKGGAQQDRFLAGTQQIALRMAEQLG-----DRVVLGAPVRRI
TH_0685|M.thermoresistible__bu GLGRMLDVEGGAQQDRFPAGTQQIAQRMAEELDGAEPGSRVRLGAPVRRI
MSMEG_2035|M.smegmatis_MC2_155 GLTRLLDVEGGAQQDRLVEGTQQIALRMADELG-----QRIALDAPVQRI
Mb3195|M.bovis_AF2122/97 GLDRLLDVKNGAQQDRVPGGTQQIAQAAAAQLG-----ARVLLNAAVRRI
Rv3170|M.tuberculosis_H37Rv GLDRLLDVKNGAQQDRVPGGTQQIAQAAAAQLG-----ARVLLNAAVRRI
MMAR_1389|M.marinum_M GLDRLLDVENGAQQELIPGGTQQIAELAAAELG-----THVVLDAPVRRI
MUL_2487|M.ulcerans_Agy99 GLDRLLDVENGAQQELIPGGTQQIAELAAAELG-----IHVVLDAPVRRI
MAV_4062|M.avium_104 GLDRLLDVEDGAQQDRFPGGTQQIAAAAAAELG-----ARVVLGAPVRRI
MAB_2659|M.abscessus_ATCC_1997 GLDHMLAVEHGQQEYRVTETTQEIAKRLAAQIG-----DQIVLNTRVRQI
** ::* *: * *: . **:** * ::. :: :.: *::*
Mflv_4501|M.gilvum_PYR-GCK TRNPDRTVTVTT-AGAEYQAGAVIVAVPPEHRSGIEFDPPLPAEHRELSR
Mvan_1866|M.vanbaalenii_PYR-1 ARHPDHSLTVGT-DRAEYTAAAVVVAIPPAHRGAVEFDPPLPADYGELNR
TH_0685|M.thermoresistible__bu TRNPDGTVTVHTGSGDGVTAGAVVVAVPPAHRDAIEFDPALPPRHTALPG
MSMEG_2035|M.smegmatis_MC2_155 ERHSGGDIGVTF-TTGHVRARAVVIAIAPQHRGDIEFDPPLPPEYTELAA
Mb3195|M.bovis_AF2122/97 DRHGAG-VTVTS-DQGQAEAGFVIVAIPPAHRVAIEFDPPLPPEYQQLAH
Rv3170|M.tuberculosis_H37Rv DRHGAG-VTVTS-DQGQAEAGFVIVAIPPAHRVAIEFDPPLPPEYQQLAH
MMAR_1389|M.marinum_M DRHGAG-VTVTS-DQGQAEAGFVIVAIPPAHRAAIEFNPPLPTGYQELAD
MUL_2487|M.ulcerans_Agy99 DRHGAG-VTVTS-DQGQAEAGFVIVAIPPAHRAAIEFNPPLPTGYQELAD
MAV_4062|M.avium_104 ERHGAG-VTVRT-DLGDTEAGFVIVAIPPAHRAAIEFAPPLPAEYEQLAR
MAB_2659|M.abscessus_ATCC_1997 SQDDNG-VTVST-DSGVINAKYAIVTAAPEHRAYIEYQPALPAKIEGLTT
:. : * * .::: .* ** :*: *.**. *
Mflv_4501|M.gilvum_PYR-GCK HWPQGRLSKAYAAYETPFWRADGHSGESLSDEGPVFITFDCSPGDDGPGV
Mvan_1866|M.vanbaalenii_PYR-1 HWPQGHLSKAYAAYQTPFWRTNGCSGEALSDEGPVFITFDCSPGDGGPGV
TH_0685|M.thermoresistible__bu HWPQGMLSKAYAAYDTPFWRADGRSGEALSDDGPVFITFDVSPDENGPGI
MSMEG_2035|M.smegmatis_MC2_155 RWPQGRLSKAYAAYDRPFWRANGCSGEALSDEGPVFITFDVSPGDEGPGI
Mb3195|M.bovis_AF2122/97 HWPQGRLSKAYAAYSTPFWRASGYSGQALSDEAPVFITFDVSPHADGPGI
Rv3170|M.tuberculosis_H37Rv HWPQGRLSKAYAAYSTPFWRASGYSGQALSDEAPVFITFDVSPHADGPGI
MMAR_1389|M.marinum_M NWPQGRLSKAYAAYSTPFWRINGFTGQSLSDIGPVFITFDASPHDDGPGI
MUL_2487|M.ulcerans_Agy99 NWPQGRLSKAYAAYSTPFWRINGFTGQSLSDMGPVFITFDASPHDDAPGI
MAV_4062|M.avium_104 HWPQGRLSKAYAAYSTPFWRADGFSGQALSDEGPVFITFDVSPHPDGPGI
MAB_2659|M.abscessus_ATCC_1997 SFPMGALSKAFVAYDKPFWRAEGLSGEALTDTAPVFITFDVSPSDDGPGI
:* * ****:.**. **** .* :*::*:* .******* ** .**:
Mflv_4501|M.gilvum_PYR-GCK LLGFTDPRSFDPLPGEQRREIALAGFSALFGAAAAHPIDYVDHCWGAEPF
Mvan_1866|M.vanbaalenii_PYR-1 LLGFTDARTFDPLPPEQRREVALAGFTALFGEAASRPLDYLDHCWGAETF
TH_0685|M.thermoresistible__bu LLGFTDARTFDPLSPDRRRDKALHGFAKLFGDAALKPIDYLDFCWGCDDF
MSMEG_2035|M.smegmatis_MC2_155 LLGFTDARTFDALPPEQRRQRALGGFATFFGDAARDPIDYLDHCWGTEAF
Mb3195|M.bovis_AF2122/97 LMGFVDARGFDSLPIEERRRDALRCFASLFGDEALDPLDYVDYRWGTEEF
Rv3170|M.tuberculosis_H37Rv LMGFVDARGFDSLPIEERRRDALRCFASLFGDEALDPLDYVDYRWGTEEF
MMAR_1389|M.marinum_M LMGFVDAREFDSLSADQRRDRTLRCFASLFGDDALEPLDYVDYCWGTEQF
MUL_2487|M.ulcerans_Agy99 LMGFVDAREFDSLSADQRRDRTLRCFASLFGDDALEPLDYADYCWGTEQF
MAV_4062|M.avium_104 LMGFVDARAFDSLPADQRRRDALRCFATLFGDDALKPLDYVDHRWGAEEF
MAB_2659|M.abscessus_ATCC_1997 LMVFCTARVYDGFGPEVRRKLVLKQLVDLYGEQANTPIDYIDHCWGTEPF
*: * .* :* : : ** .* : ::* * *:** *. ** : *
Mflv_4501|M.gilvum_PYR-GCK SPGGPTAAVPPGAWTAHGRWLRAPVDGIFWAGTETADSWTGFLDGAVRSG
Mvan_1866|M.vanbaalenii_PYR-1 APGGPTAAVPPGAWTAHGRWLRAPVDGIFWAGTETADRWTGFLDGAVRSG
TH_0685|M.thermoresistible__bu APGGPTAAVPPGSWTEFGPWLREPVDQIYWAGTETADQWTGFLDGAVRSG
MSMEG_2035|M.smegmatis_MC2_155 APGGPTAAVPPEAWTAYGPWLRKPIDGIHWAGTETADVWTGFLDGAVRSG
Mb3195|M.bovis_AF2122/97 APGGPTAAVPPGSWTKYGHWLREPVGPIHWASTETADEWTGYFDGAVRSG
Rv3170|M.tuberculosis_H37Rv APGGPTAAVPPGSWTKYGHWLREPVGPIHWASTETADEWTGYFDGAVRSG
MMAR_1389|M.marinum_M APGGPTAAVPPGSWTRYGQLLRKPVGPIHWAGTETADEWTGYFDGAVRSG
MUL_2487|M.ulcerans_Agy99 APGGPTAAVPPGSWTRYGQLLRKPVGPIHWAGTETADEWTGYFDGAVRAG
MAV_4062|M.avium_104 APGGPTAAVPPGSWTRFGRWLREPVGPIHWAGTETADEWTGFLDGAIRSG
MAB_2659|M.abscessus_ATCC_1997 AAGGPHPAAPPFASVNYGEALREPHGRIHWAGTETAGEWVGTMNGAILMG
:.*** .*.** : . .* ** * . *.**.****. *.* ::**: *
Mflv_4501|M.gilvum_PYR-GCK LRAADEAHRELARA-----
Mvan_1866|M.vanbaalenii_PYR-1 LRAATDVHQELTRRS----
TH_0685|M.thermoresistible__bu QRAAAEVHRRLSSGG----
MSMEG_2035|M.smegmatis_MC2_155 QRAATEVAEALKSSAAAG-
Mb3195|M.bovis_AF2122/97 QRAAAEVAALL--------
Rv3170|M.tuberculosis_H37Rv QRAAAEVAALL--------
MMAR_1389|M.marinum_M QRAAAEVAALL--------
MUL_2487|M.ulcerans_Agy99 QRAAAEVAALL--------
MAV_4062|M.avium_104 RRAAAEVTALL--------
MAB_2659|M.abscessus_ATCC_1997 LHTADQIAQQLGVTGEVSK
::* : *