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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2921 | aofH_1 | - | 100% (453) | putative flavin-containing monoamine oxidase AofH_1 |
| M. thermoresistible (build 8) | TH_0685 | - | 6e-88 | 40.52% (459) | PROBABLE FLAVIN-CONTAINING MONOAMINE OXIDASE AOFH (AMINE |
| M. thermoresistible (build 8) | TH_1483 | - | 1e-05 | 33.04% (112) | dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3195 | aofH | 3e-88 | 40.76% (449) | flavin-containing monoamine oxidase |
| M. gilvum PYR-GCK | Mflv_1230 | - | 8e-95 | 43.48% (460) | amine oxidase (flavin-containing) |
| M. tuberculosis H37Rv | Rv3170 | aofH | 3e-88 | 40.76% (449) | flavin-containing monoamine oxidase |
| M. leprae Br4923 | MLBr_01226 | nadB | 1e-05 | 48.89% (45) | L-aspartate oxidase |
| M. abscessus ATCC 19977 | MAB_2659 | - | 5e-72 | 34.00% (450) | putative flavin-containing monoamine oxidase AofH |
| M. marinum M | MMAR_3362 | aofH_1 | 1e-100 | 44.42% (448) | flavin-containing monoamine oxidase AofH_1 |
| M. avium 104 | MAV_4062 | - | 2e-92 | 42.54% (449) | putative flavin-containing monoamine oxidase AofH |
| M. smegmatis MC2 155 | MSMEG_2035 | - | 2e-95 | 42.07% (454) | amine oxidase |
| M. ulcerans Agy99 | MUL_1281 | aofH_1 | 1e-100 | 44.20% (448) | flavin-containing monoamine oxidase AofH_1 |
| M. vanbaalenii PYR-1 | Mvan_5578 | - | 2e-96 | 44.86% (457) | amine oxidase (flavin-containing) |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3195|M.bovis_AF2122/97 MT------NPPWTVDVVVVGAGFAGLAAARELTRQGHEVLVFEGRDRVGG
Rv3170|M.tuberculosis_H37Rv MT------NPPWTVDVVVVGAGFAGLAAARELTRQGHEVLVFEGRDRVGG
MAV_4062|M.avium_104 MS------GPPRIVDVVVVGAGFAGLAAARELNRQGHDVVVFEGRDRVGG
MSMEG_2035|M.smegmatis_MC2_155 MS------IPT-SADVVVVGAGFAGLTAARRLVQLGYDVVVLEGRDRVGG
MAB_2659|M.abscessus_ATCC_1997 MSRSVDNAVEAASVDVVIVGAGFAGLSAADRLVNMGVSVLVIDARERVGG
Mflv_1230|M.gilvum_PYR-GCK --------MARDEADVLIVGAGISGLIAARTVLAAGLTPLVVEADTRVGG
Mvan_5578|M.vanbaalenii_PYR-1 -----MSGMTGHEADVVVVGAGLSGLIAARTLLGAGLTPLILEADTRVGG
TH_2921|M.thermoresistible__bu ---------------VVVVGAGLAGLTAARTLRRAGVDVVVLEARDRVGG
MMAR_3362|M.marinum_M ----------MAEVDVCVVGAGFAGLTAALRLKQAGHSVALLEARDRVGG
MUL_1281|M.ulcerans_Agy99 ----------MAEVDVCVVGAGFAGLTAALRLKQAGHSVALLEARDRVGG
MLBr_01226|M.leprae_Br4923 ---MMAVPDWKHAADVVVIGTGVAGLAAALAAHRAGRNVVVLTKADQRRG
* ::*:*.:** ** * :. : *
Mb3195|M.bovis_AF2122/97 RSLTGRVAGVP-------ADMGGSFIGPTQDAVLALATELGIPTTPTHR-
Rv3170|M.tuberculosis_H37Rv RSLTGRVAGVP-------ADMGGSFIGPTQDAVLALATELGIPTTPTHR-
MAV_4062|M.avium_104 RSFTGSVAGLP-------ADLGGTFVGPTQDAVLALAAELEVPTTPTHH-
MSMEG_2035|M.smegmatis_MC2_155 RSSTATIAGVP-------VDLGGTFVGPTQDAVLGLAAELGCATVPTYN-
MAB_2659|M.abscessus_ATCC_1997 RSFTGEVAGVK-------VDLGATWVAKRHTAIRDLMDRLGCSLTPQYD-
Mflv_1230|M.gilvum_PYR-GCK RVLTEELAGLP-------MELGAQWIGDTHHRMFALAAELGVETYPQYD-
Mvan_5578|M.vanbaalenii_PYR-1 RILTEDLGGLP-------MELGAQWIGDTHHRMFALAAELGVETYPQFD-
TH_2921|M.thermoresistible__bu RTLNHFLEHGPDPENDAVVELGGQWIGPGHQRIRALIDELGLSTFDTYD-
MMAR_3362|M.marinum_M RTFTVVREDGS------WIDKGGAWIGPTQHRIYALMKEFGVAAFKQYT-
MUL_1281|M.ulcerans_Agy99 RTFTVVREDGS------WIDKGGAWIGPTQHRIYALMKEFGVAAFKQYT-
MLBr_01226|M.leprae_Br4923 ETATHYAQGGIA------VVLPGSDDSVDAHASDTLAAGAGMCNLDTVYS
. . . . *
Mb3195|M.bovis_AF2122/97 ----DGRNVIQWRGSARSYRGTIP--------------KLS-LTGLIDIG
Rv3170|M.tuberculosis_H37Rv ----DGRNVIQWRGSARSYRGTIP--------------KLS-LTGLIDIG
MAV_4062|M.avium_104 ----EGKNLIHWRGWTHAYHGTIP--------------KLS-LTGLLDIG
MSMEG_2035|M.smegmatis_MC2_155 ----RGKNLIRWHGRVRSYRSTIP--------------RLS-IIELLDVS
MAB_2659|M.abscessus_ATCC_1997 ----EGVNLLWMAGKRKTWTGTLP--------------TVD-PVDLEDLG
Mflv_1230|M.gilvum_PYR-GCK ----DGETSYELAGTGVLRGNDFH--------------ERF-AGELAELE
Mvan_5578|M.vanbaalenii_PYR-1 ----DGETTYELAGTGVLRGNEFH--------------DRF-AGELAELE
TH_2921|M.thermoresistible__bu ----RGAKLWEHNGRVRRYTGEIP--------------RAN-PLHLADLQ
MMAR_3362|M.marinum_M ----DGEAMMVVDGKQYRYQGTIP--------------RTLSPLASMNLG
MUL_1281|M.ulcerans_Agy99 ----DGEAMMVVDGKQYRYQGTIP--------------RTLSPLASMNLG
MLBr_01226|M.leprae_Br4923 IVAEGYHAVTELVGYGARFDESIPGRWAVTCEGGHSRRRIVHAGGDATGA
* :
Mb3195|M.bovis_AF2122/97 RLRWQFERIARGVPVAAPWDARRARELDDVSLGEWLRL------------
Rv3170|M.tuberculosis_H37Rv RLRWQFERIARGVPVAAPWDARRARELDDVSLGEWLRL------------
MAV_4062|M.avium_104 RLRWQFDRIARSIPLAAPWEARRAAELDGLSLGGWLRS------------
MSMEG_2035|M.smegmatis_MC2_155 RIQWRFERLFRHVDVAEPWNGSLAHKLDQYSMERWLRY------------
MAB_2659|M.abscessus_ATCC_1997 RITIEMGKLLETINVDAAWKSPNADQLDSISFGEWLSQ------------
Mflv_1230|M.gilvum_PYR-GCK KVLRRLDELAAEVCAATPWTAPHAAEWDAITAGAWYDA------------
Mvan_5578|M.vanbaalenii_PYR-1 KVLRRLDGLATEVDPATPWTAPHAAEWDAITAGAWYDA------------
TH_2921|M.thermoresistible__bu IALTRLERMARRIDPAAPWAAPRAAQWDRQTVAGWIDR------------
MMAR_3362|M.marinum_M TAMFEISQMCKTIPLEAPWEAKRAAKWDRMTLAQWLRN------------
MUL_1281|M.ulcerans_Agy99 TAMFEISQMCKTIPLEAPWEAKRAAKWDRMTLAQWLRN------------
MLBr_01226|M.leprae_Br4923 EVQRALDHAADVLDIRTSHLALRVLHDGTVVNGVSVLNPNGWGIVSAPSV
: : . . . . .
Mb3195|M.bovis_AF2122/97 --------------VRATSSSRNLMAIMTRVTWGCEPDDVSMLHAARYVR
Rv3170|M.tuberculosis_H37Rv --------------VRATSSSRNLMAIMTRVTWGCEPDDVSMLHAARYVR
MAV_4062|M.avium_104 --------------VRATASSHALLAMVARVTWGCEPDEVSMLHAARYAH
MSMEG_2035|M.smegmatis_MC2_155 --------------VHANASTRNLMAIMSRVTWGAEPDQVSMLHAVRYVK
MAB_2659|M.abscessus_ATCC_1997 --------------QQAVTSTNALMYIVTRVQWGCSPLDVSLLHVLRYVQ
Mflv_1230|M.gilvum_PYR-GCK --------------QGLSPVARTLLEICTVGILAVPTVEVSFLHLLFTIQ
Mvan_5578|M.vanbaalenii_PYR-1 --------------QGLSPVARTLLEICTVGILAVPTVEVSFLHLLFTIQ
TH_2921|M.thermoresistible__bu --------------HVRTAVGRAFIELVCEAVWAADAADLSLLHLLTYTS
MMAR_3362|M.marinum_M --------------NVKSKAAHDLLETAIAGCYTSDASEVSMLFVLYQMA
MUL_1281|M.ulcerans_Agy99 --------------NVKSKAAHDLLETAIAGCYTSDASEVSMLFVLYQMA
MLBr_01226|M.leprae_Br4923 ILASGGLGHLYGATTNPEGSTGDGIALALWAGVAVSDLEFIQFHPTMLFA
: :. :.
Mb3195|M.bovis_AF2122/97 AAGGLD---------------RLLD-VKNGAQQDRVPGGTQQIAQAAAAQ
Rv3170|M.tuberculosis_H37Rv AAGGLD---------------RLLD-VKNGAQQDRVPGGTQQIAQAAAAQ
MAV_4062|M.avium_104 AAGGLD---------------RLLD-VEDGAQQDRFPGGTQQIAAAAAAE
MSMEG_2035|M.smegmatis_MC2_155 AAGGLT---------------RLLD-VEGGAQQDRLVEGTQQIALRMADE
MAB_2659|M.abscessus_ATCC_1997 AVGGLD---------------HMLA-VEHGQQEYRVTETTQEIAKRLAAQ
Mflv_1230|M.gilvum_PYR-GCK TCGVTA---------------ELFAESEGGAQTTRFVGGTAEIPKRLAAL
Mvan_5578|M.vanbaalenii_PYR-1 TCGVTS---------------ELFAESEGGAQTTRFVGGTAEIPKRLAAM
TH_2921|M.thermoresistible__bu SNQGLS---------------QLIT-TRGGAQQSRIIGGAQQISTAMADE
MMAR_3362|M.marinum_M SGGGPG---------------FVLG-SKGAAQDARPIGGMGAVYGPMAAE
MUL_1281|M.ulcerans_Agy99 SGGGPG---------------FVLG-SKGAAQDARPIGGMGAVYGPMAAE
MLBr_01226|M.leprae_Br4923 AGTGTGGRRPLVTEAIRGEGAILLDSKGNSVTSGVHPLGDLAPRDVVAAA
: :: . *
Mb3195|M.bovis_AF2122/97 LGARVLLN------AAVRRIDRHGAG-VTVTSDQGQAEAGFVIVAIPPAH
Rv3170|M.tuberculosis_H37Rv LGARVLLN------AAVRRIDRHGAG-VTVTSDQGQAEAGFVIVAIPPAH
MAV_4062|M.avium_104 LGARVVLG------APVRRIERHGAG-VTVRTDLGDTEAGFVIVAIPPAH
MSMEG_2035|M.smegmatis_MC2_155 LGQRIALD------APVQRIERHSGGDIGVTFTTGHVRARAVVIAIAPQH
MAB_2659|M.abscessus_ATCC_1997 IGDQIVLN------TRVRQISQDDNG-VTVSTDSGVINAKYAIVTAAPEH
Mflv_1230|M.gilvum_PYR-GCK ISEHIVLD------SPVQLIEHRADSVTLHCRGGRTAQGRRVIVAVSPTL
Mvan_5578|M.vanbaalenii_PYR-1 LTEHLVLD------APVQLIEHGSDSVTVHCRGGRTARGRRIIVAVSPML
TH_2921|M.thermoresistible__bu LGDAVRLG------APVREIRTR-DGVQVVADT-ATVRAERVVVAMSPTL
MMAR_3362|M.marinum_M LGDAIHLS------QPVRSITQDSGGVTVQAEG-LTVRANRTIVAVPLAI
MUL_1281|M.ulcerans_Agy99 LGDAIHLS------QPVRSITQDSGGVTVQAEG-LTVRANRTIVAVPLAI
MLBr_01226|M.leprae_Br4923 IDARLKATGDSCVYLDARGIDGFASRFPTVTAACRTVGIDPAREPIPVVP
: : .: * . .
Mb3195|M.bovis_AF2122/97 RVAIEFDPPLPPEY--QQLAHHWPQGRLSKAYAAYSTPFWRASGYSGQAL
Rv3170|M.tuberculosis_H37Rv RVAIEFDPPLPPEY--QQLAHHWPQGRLSKAYAAYSTPFWRASGYSGQAL
MAV_4062|M.avium_104 RAAIEFAPPLPAEY--EQLARHWPQGRLSKAYAAYSTPFWRADGFSGQAL
MSMEG_2035|M.smegmatis_MC2_155 RGDIEFDPPLPPEY--TELAARWPQGRLSKAYAAYDRPFWRANGCSGEAL
MAB_2659|M.abscessus_ATCC_1997 RAYIEYQPALPAKI--EGLTTSFPMGALSKAFVAYDKPFWRAEGLSGEAL
Mflv_1230|M.gilvum_PYR-GCK AGRIMYDPPLSGYR--DQLTQRMPNSAAMKAFFVYDEPFWRADGLNGQLI
Mvan_5578|M.vanbaalenii_PYR-1 AGRIMYDPPLSGYR--DQLTQRMPNSAAMKAFFVYDEPFWRADGLNGQLI
TH_2921|M.thermoresistible__bu AGRLHYDEPLPADR--DQLTQRMPNGSVVKCMAIYDEPFWRADGLSGQGV
MMAR_3362|M.marinum_M ASQIVYEPMLPTDR--SFLHQRMPSGAVVKISAVYDEPFWRADGLCGQSA
MUL_1281|M.ulcerans_Agy99 ASQIVYEPMLPTDR--SFLHQRMPSGAVVKISAVYDEPFWRADGLCGQSA
MLBr_01226|M.leprae_Br4923 GAHYSCGGIVTDAYGQTELAGLFAAGEVARTGMHGANRLASNSLLEGLVV
:. * . . : : . *
Mb3195|M.bovis_AF2122/97 SDEAPVFITFDVSPHADGPGILMGFVD---ARGFDSLPIEERRRDALRCF
Rv3170|M.tuberculosis_H37Rv SDEAPVFITFDVSPHADGPGILMGFVD---ARGFDSLPIEERRRDALRCF
MAV_4062|M.avium_104 SDEGPVFITFDVSPHPDGPGILMGFVD---ARAFDSLPADQRRRDALRCF
MSMEG_2035|M.smegmatis_MC2_155 SDEGPVFITFDVSPGDEGPGILLGFTD---ARTFDALPPEQRRQRALGGF
MAB_2659|M.abscessus_ATCC_1997 TDTAPVFITFDVSPSDDGPGILMVFCT---ARVYDGFGPEVRRKLVLKQL
Mflv_1230|M.gilvum_PYR-GCK SDIGPARMSNDTCIQGDDHGVILLFLEGEQARTHGHWSEEERREALTAEL
Mvan_5578|M.vanbaalenii_PYR-1 SDVGPARMSNDTCIRGDDRGVILLFLEGEQARTHGHWSEEERRAALTAEL
TH_2921|M.thermoresistible__bu GFTGPVKVFFDNSPPSGRPGVLLGFLEGSQARELGRADTRTRREAVIGCF
MMAR_3362|M.marinum_M APTSLATLTIDASPNSGTPGVLCVVIEGPVARQYERLDDDGRRQAVLAAL
MUL_1281|M.ulcerans_Agy99 APTSLATLTIDASPNSGTPGVLCVVIEGPVARQYERLDDDGRRQAVLAAL
MLBr_01226|M.leprae_Br4923 GGRAGRAAAAHAAAAGRAYVSKLEPVTHHALKRRELQRVMSRDAAVMRNA
. . . : *
Mb3195|M.bovis_AF2122/97 ASLFGDEALDPLDYVDYRWGTEEFAPGGPTAAVPPGSWTKYGHWLREPVG
Rv3170|M.tuberculosis_H37Rv ASLFGDEALDPLDYVDYRWGTEEFAPGGPTAAVPPGSWTKYGHWLREPVG
MAV_4062|M.avium_104 ATLFGDDALKPLDYVDHRWGAEEFAPGGPTAAVPPGSWTRFGRWLREPVG
MSMEG_2035|M.smegmatis_MC2_155 ATFFGDAARDPIDYLDHCWGTEAFAPGGPTAAVPPEAWTAYGPWLRKPID
MAB_2659|M.abscessus_ATCC_1997 VDLYGEQANTPIDYIDHCWGTEPFAAGGPHPAAPPFASVNYGEALREPHG
Mflv_1230|M.gilvum_PYR-GCK VRHFGDRAARPSHYIDGEWGSRQWTRGCYNANCGPLVWTTYGAALAEPIG
Mvan_5578|M.vanbaalenii_PYR-1 VRHFGERAAHPQLYVDGEWGSRQWTRGCYNANCGPLVWTTYGAALAEPIG
TH_2921|M.thermoresistible__bu ARMFGPRAARPVDYVEKVWAADQWTRGCYGAFLPPNTWTQVGPALRRAVG
MMAR_3362|M.marinum_M VERFGAKAAKPIDYFEQNWSRERYSGGGMLSHTPPGVLTQFGHALRRPCG
MUL_1281|M.ulcerans_Agy99 VERFGAKAAKPIDYFEQNWSRERYSGGGMLSHTPPGVLTQFGHALRRPCG
MLBr_01226|M.leprae_Br4923 AGLQRLSDTLAEAPIRHVTGRRDFEDVALTLTARAVAAAALARNESRGCH
. . . . : . . . .
Mb3195|M.bovis_AF2122/97 PIHWASTETADEWTGYFDGAVRSGQRAAAEVAALL--------
Rv3170|M.tuberculosis_H37Rv PIHWASTETADEWTGYFDGAVRSGQRAAAEVAALL--------
MAV_4062|M.avium_104 PIHWAGTETADEWTGFLDGAIRSGRRAAAEVTALL--------
MSMEG_2035|M.smegmatis_MC2_155 GIHWAGTETADVWTGFLDGAVRSGQRAATEVAEALKSSAAAG-
MAB_2659|M.abscessus_ATCC_1997 RIHWAGTETAGEWVGTMNGAILMGLHTADQIAQQLGVTGEVSK
Mflv_1230|M.gilvum_PYR-GCK VIHWASTDTAVEWSAYMEGAVEAGERAAREVIDALVSQRDR--
Mvan_5578|M.vanbaalenii_PYR-1 PIHWASTDTATEWSAYMEGAVQAGERAAAEVIEALTK------
TH_2921|M.thermoresistible__bu PIHWAGAETAVRSMGYMDGAVASGERAAAEVLTALGSGA----
MMAR_3362|M.marinum_M RIHWAGTETSAKMCGWIDGAIRSGERAASEVMANQTMTMASDS
MUL_1281|M.ulcerans_Agy99 RIHWAGTEISAKMCGWIDGAIRSGERAASEVMANQTMTMASDS
MLBr_01226|M.leprae_Br4923 HCTEYPDTAPEHARSTVIRLADDQNLVRAEALATVG-------
. . . . :