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SNLHAKPHRPFLGHLIRVLSLPIILFWVALAVILGTVTPSLTDVAASRSVPLSPQNSESYQGMLNIGKVF QQYDSDSSAMVVLEGDDKLGDSAHQYYDDIVAKLKADHEHVQNVQDFWSDPLTAAGSQSVDGKAAYVQIF LNGSQGTSASHESVAAVRHIVDSVPAPPGIKAHVAGTTVLNADTQVAGHQSMATMELVSVGVIIVMILFI YRSIVTMLISMVIIGLELFAAQGVTATAGYLNVIGLTPYAVSMVTMLALAAGTDYVIFLFGRYHEERSKG LSREDAYYVAYHGVSHVILGSGLTIVGACLCLTMTTLPYFQSMALPCAISVLVIVAAALTLAPAVLTVAS KFGLLEPRGKLSTTGWRKVGTSVVRWPIPIIVLTSLIAIIGFVSLMTYVPQYNDQKFTPADMPANLAMEV ADRHFSQARMNPELLMLEADHDLRTPADMLVIDRVAKGIVHMRGIERVQTITRPLGAPIEHSSIPFLMGA QNAGTLQTAKFNNENSAQMLEQADELSRTVASMERMYSLMQELTGTMHSMVGRTHEMEATIQEMRDNLAN FDDFFRPLRNYFYWEKHCFDIPICQSLRSIFDVLDSVDVLADQMHGLIADMDHMDQLMPQMLPVLRTTID SMGRMRDFMIATHSTMAGTQAQQQELAKGATEIGLYFDQAKNDDFFYLPPDVFTNPDFKRGLKMFVSPDG KAVRFIITHQGDPASVEGIDHVRDLKGVVADAVKGTPLSNAKVSIAGTASMYADMQDGVSIDLMIAVIAS MILIFAIMVLITRSVVAALVIVGTVAASLGTACGLSVLLWQDILGLGVQWIVIPLSMVILLAVGSDYNLL VVSRLKEEIHAGLNTGMIRGMGATGRVVTAAGLVFAFTMMSMIVSDLRVVGQLGMTIGIGLIVDTLIVRA FMTPSIAAALGRWFWWPINVFEIVRRGRETQAPEPVTAPLPVVDAGPQPPTAPSTS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4310c | - | - | 100% (967) | MmpL family protein |
| M. abscessus ATCC 19977 | MAB_3150 | - | 0.0 | 58.63% (921) | MmpL family protein |
| M. abscessus ATCC 19977 | MAB_1134c | - | 0.0 | 52.62% (975) | membrane protein MmpL |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0458c | mmpL4 | 0.0 | 55.13% (956) | transmembrane transport protein MmpL4 |
| M. gilvum PYR-GCK | Mflv_3435 | - | 0.0 | 52.45% (940) | transport protein |
| M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 55.13% (956) | transmembrane transport protein MmpL4 |
| M. leprae Br4923 | MLBr_02378 | - | 0.0 | 54.22% (924) | hypothetical protein MLBr_02378 |
| M. marinum M | MMAR_0775 | - | 0.0 | 55.33% (947) | MmpL family transport protein |
| M. avium 104 | MAV_4755 | - | 0.0 | 72.67% (933) | MmpL4 protein |
| M. smegmatis MC2 155 | MSMEG_0463 | - | 0.0 | 82.52% (961) | MmpL4 protein |
| M. thermoresistible (build 8) | TH_3260 | - | 0.0 | 49.85% (969) | PUTATIVE MmpL4 protein |
| M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 52.64% (946) | transmembrane transport protein, MmpL5 |
| M. vanbaalenii PYR-1 | Mvan_3189 | - | 0.0 | 52.82% (941) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0458c|M.bovis_AF2122/97 ------MSTKFANDSNTNARPEK----------------PFIARMIHAFA
Rv0450c|M.tuberculosis_H37Rv ------MSTKFANDSNTNARPEK----------------PFIARMIHAFA
MLBr_02378|M.leprae_Br4923 ------MTVKCANDLDTHTKP------------------PFVARMIHRFA
Mflv_3435|M.gilvum_PYR-GCK ------MSAPVSDARTDEFPAAHGPHRS------------FIPRMIRLFA
Mvan_3189|M.vanbaalenii_PYR-1 ------MSAPVSDARTDEFPAARQPHRP------------FIPRMIRLFA
TH_3260|M.thermoresistible__bu ------MTANPGHVRTDEAPTDRLDIKVSTHG------PSFISTWIRRLS
MUL_0757|M.ulcerans_Agy99 ------MTATTTDTPTDVVPPAEHPPRP------------FIPRMIRTFA
MMAR_0775|M.marinum_M MSDDQAVSERAASNGASNGAGAENGNGNENGNGNGNGSRPSMARLIHRMA
MAB_4310c|M.abscessus_ATCC_199 ------MSNLHAKPHR-----------------------PFLGHLIRVLS
MSMEG_0463|M.smegmatis_MC2_155 ------MTNTHSKSQR-----------------------PFVGHVIRIFS
MAV_4755|M.avium_104 -----------------------------------------------MLS
::
Mb0458c|M.bovis_AF2122/97 VPIILGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVF
Rv0450c|M.tuberculosis_H37Rv VPIILGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVF
MLBr_02378|M.leprae_Br4923 VPIILVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVF
Mflv_3435|M.gilvum_PYR-GCK VPIILGWIALIVVVNVTVPQLETVGEAQAVSMSPNDAPSMISMKKVGELF
Mvan_3189|M.vanbaalenii_PYR-1 VPIILGWIALIVILNVTVPQLEAVGEARAVSMSPNEAPSLISMKKVGELF
TH_3260|M.thermoresistible__bu LPIIVGWIALIALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELF
MUL_0757|M.ulcerans_Agy99 VPLILGWVLLIAVLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVF
MMAR_0775|M.marinum_M VPIVVFWVGLVAVLVMFVPSLEEVGKQHTVSLSPSDAESMIAMKRVGKVF
MAB_4310c|M.abscessus_ATCC_199 LPIILFWVALAVILGTVTPSLTDVAASRSVPLSPQNSESYQGMLNIGKVF
MSMEG_0463|M.smegmatis_MC2_155 LPIVLLWVLLVVALGAIFPSLDDVAATRSVPLSPTDSQAYQSMLNIGKVF
MAV_4755|M.avium_104 LPITLGWVFVAVALGVLSPSLDDVASQHSVPMTPRDAPAFKSMMHIGDKF
:*: : *: : . : *.* *. ::*.::* : : .* .:* *
Mb0458c|M.bovis_AF2122/97 KEGDSDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGD
Rv0450c|M.tuberculosis_H37Rv KEGDSDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGD
MLBr_02378|M.leprae_Br4923 NEGNSDSVIMIVLEGDKPLGDDAHRFYDGLIRKLRADK-HVQSVQDFWGD
Mflv_3435|M.gilvum_PYR-GCK EEGDSDSSVMIVFEGDQPLGDEAHAWYDELVDRLEADTAHVQSVQDFWSD
Mvan_3189|M.vanbaalenii_PYR-1 REGDSDSSVMIVFEGDQPLGDEAHAWYDELVERLRADTKHVQSVQDFWSD
TH_3260|M.thermoresistible__bu DEGSSDSQVMIVLEGEEPLGADARAFYDELVKRLEADDAHVENVQDLWSD
MUL_0757|M.ulcerans_Agy99 REGDSDSAAMIVLEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGD
MMAR_0775|M.marinum_M NEFDTDSAVMIVLEGDHPLGDEAHHYYDELVRKLKADKDHVQHVQDFWGD
MAB_4310c|M.abscessus_ATCC_199 QQYDSDSSAMVVLEGDDKLGDSAHQYYDDIVAKLKADHEHVQNVQDFWSD
MSMEG_0463|M.smegmatis_MC2_155 RQYDSDSTAMVVLEGEDKLGDAAHKYYDEIVAKLRADHEHVQNVQDFWSD
MAV_4755|M.avium_104 NEFHTDSTAMVVLEGKDKLGDSAHEFYDRIVRKLRDDHQHVQNIQDFWSD
: :** *:::**.. ** *: :** :: :*. * **: :**:*.*
Mb0458c|M.bovis_AF2122/97 PLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTP---AP
Rv0450c|M.tuberculosis_H37Rv PLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTP---AP
MLBr_02378|M.leprae_Br4923 PLTAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQTP---AP
Mflv_3435|M.gilvum_PYR-GCK PLTASGSQSNDGKAAYVQVKLSGNQGEALANESVKAVQQTVSSLE---PP
Mvan_3189|M.vanbaalenii_PYR-1 PLTASGSQSNDGKAAYVQVKLAGNQGESLANESVQAAQEIVRSLE---PP
TH_3260|M.thermoresistible__bu PLTATGVQSPDGKSAYVQVKLAGNQGEALANESVETVREMIATVSEEMAP
MUL_0757|M.ulcerans_Agy99 PLTATGAQSGDGKAAYVQVKLAGNQGESLANESVEAVKTIVDSLQ---AP
MMAR_0775|M.marinum_M PLTAAGSQSPDGKAAYVQAYLVGNQGEAKANESVDAVRELVNDTP---AP
MAB_4310c|M.abscessus_ATCC_199 PLTAAGSQSVDGKAAYVQIFLNGSQGTSASHESVAAVRHIVDSVP---AP
MSMEG_0463|M.smegmatis_MC2_155 PLTAAGSQSVDGRSAYVQIFLNGPQGTTASYESVAAVRDIVESVP---PP
MAV_4755|M.avium_104 PLTAAGSQSPDGKSAYVQVFLNGAQGTTPSYESVAAVRKIVDSTP---AP
****.* ** **::**** * * ** : **: :.: : .*
Mb0458c|M.bovis_AF2122/97 PGIKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITV
Rv0450c|M.tuberculosis_H37Rv PGIKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITV
MLBr_02378|M.leprae_Br4923 PGITAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITV
Mflv_3435|M.gilvum_PYR-GCK PGVRAFVTGPAALAADQHIAGDRSMRLIEAATFTVIIVMLLLVYRSIVTV
Mvan_3189|M.vanbaalenii_PYR-1 PGVRAFVTGPAALAADQHIASDRSVRVIELVTFAVIIVMLLLVYRSIVTV
TH_3260|M.thermoresistible__bu EGVQAFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVITV
MUL_0757|M.ulcerans_Agy99 PGVKVYVTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITA
MMAR_0775|M.marinum_M PGVKAYVTGPAALIADQSTAGDASIQRVTFITIGVIFVMLLSVYRSLITV
MAB_4310c|M.abscessus_ATCC_199 PGIKAHVAGTTVLNADTQVAGHQSMATMELVSVGVIIVMILFIYRSIVTM
MSMEG_0463|M.smegmatis_MC2_155 PGIKAHVAGTTVLNADTSVAGHQSMARMELISVAVIILMLLAIYRSIVTM
MAV_4755|M.avium_104 PGVKAYVAGNTVLNADTSIVGHKSMATMALVSIVVIFVMLLVVYRSIVTT
*: . *:* :.: ** .. *: : :. ** :* :***.:*
Mb0458c|M.bovis_AF2122/97 VLLLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGI
Rv0450c|M.tuberculosis_H37Rv VLLLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGI
MLBr_02378|M.leprae_Br4923 ILLLFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGI
Mflv_3435|M.gilvum_PYR-GCK LITLVMVVMSLATARGVVAFLGHHEIIGLSTFATNLLVTLAIAAATDYAI
Mvan_3189|M.vanbaalenii_PYR-1 LLTLVMVVLSLATARGVVAFLGWHEIIGLSLFATNLLVTLAIAAATDYAI
TH_3260|M.thermoresistible__bu LIALFMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYAI
MUL_0757|M.ulcerans_Agy99 AIMLTMVVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAI
MMAR_0775|M.marinum_M ISVLVMVGIELMAARGVVAFLADNNVIGLSTFAVNLLVLMAIAAGTDYAI
MAB_4310c|M.abscessus_ATCC_199 LISMVIIGLELFAAQGVTATAGYLNVIGLTPYAVSMVTMLALAAGTDYVI
MSMEG_0463|M.smegmatis_MC2_155 LISMVIIGLELFAAQSVTATAGHFNLIGLTPYAVSMTTMLALAAGTDYVI
MAV_4755|M.avium_104 VLSLVIIGIELFAAQGITATAGNLNIIGLTPYAVSMITMLSIAAGTDYVI
: : : .::. .* . ***: :*..: . :::* ..** *
Mb0458c|M.bovis_AF2122/97 FIIGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTITGATFCLSFARM
Rv0450c|M.tuberculosis_H37Rv FIIGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTIAGATFCLSFARM
MLBr_02378|M.leprae_Br4923 FITGRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARM
Mflv_3435|M.gilvum_PYR-GCK FLIGRYQEARTAGEDKETAYYTMFHGTAHVVLGSGLTIAGATFCLSFTRL
Mvan_3189|M.vanbaalenii_PYR-1 FLIGRYQEARTNGEDKESAYYTMFHGTAHVVLGSGLTIAGATYCLSFTRL
TH_3260|M.thermoresistible__bu FLIGRYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFTRL
MUL_0757|M.ulcerans_Agy99 FLIGRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRL
MMAR_0775|M.marinum_M FVLGRYQEARGEGESREKAFYTMFHGTAHVVLGSGLTIAGAMYCLSFTRL
MAB_4310c|M.abscessus_ATCC_199 FLFGRYHEERSKGLSREDAYYVAYHGVSHVILGSGLTIVGACLCLTMTTL
MSMEG_0463|M.smegmatis_MC2_155 FLLGRYHEERSRGLDREEAYYVAYRGVSHVILGSGLTIAGACLCLTMTTL
MAV_4755|M.avium_104 FLLGRYHEARSFGQGREEAFYTAYHGVSHVILGSGLTIAGACLCLTAARL
*: ***:* * . .: *::. : *. **:*.***** ** **: : :
Mb0458c|M.bovis_AF2122/97 PYFQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGW
Rv0450c|M.tuberculosis_H37Rv PYFQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGW
MLBr_02378|M.leprae_Br4923 PYFQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVRGW
Mflv_3435|M.gilvum_PYR-GCK PYFQTMGVPLAIGMFVVVMAGVVLMVACISVATRFGKLLEPKRAMRIRGW
Mvan_3189|M.vanbaalenii_PYR-1 PYFQTLGVPLAIGMFVVVMAGVILMVAMISVATRFGKLLEPKRAMRIRGW
TH_3260|M.thermoresistible__bu PYFQSLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARVRFW
MUL_0757|M.ulcerans_Agy99 PYFQTLGVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRGW
MMAR_0775|M.marinum_M PYFQTLGAPCAVGMLVAVLAALTLGPAVLVVGSFFK-LFDPKRKMRTRGW
MAB_4310c|M.abscessus_ATCC_199 PYFQSMALPCAISVLVIVAAALTLAPAVLTVASKFG-LLEPRGKLSTTGW
MSMEG_0463|M.smegmatis_MC2_155 PYFQSMALPCAISILVIVIAALTLAPAVLTVASRFG-LLDPKRELSTKSW
MAV_4755|M.avium_104 PYFQTMGLPCAIAMVVIVLAALTLAPAILAVGSRFG-LFDPKRAIDVRGW
****::. * *:.:.: : ..: : * : * : * *::*: *
Mb0458c|M.bovis_AF2122/97 RRVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQ
Rv0450c|M.tuberculosis_H37Rv RRVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQ
MLBr_02378|M.leprae_Br4923 RRIGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQ
Mflv_3435|M.gilvum_PYR-GCK RKIGAAIVRWPGPILVATMAITLVGLLALPGYKTNYNDRDYLPADLPANQ
Mvan_3189|M.vanbaalenii_PYR-1 RKIGAAVVRWPGPILVATLAITLVGLLALPGYKTNYNDRTYLPADLPANE
TH_3260|M.thermoresistible__bu RKVGASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSNA
MUL_0757|M.ulcerans_Agy99 RKIGAAIVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANE
MMAR_0775|M.marinum_M RRVGTAIVRWPGPILAVSIAIALIGLLALPGYRTNYDSKKYLPASTPTNV
MAB_4310c|M.abscessus_ATCC_199 RKVGTSVVRWPIPIIVLTSLIAIIGFVSLMTYVPQYNDQKFTPADMPANL
MSMEG_0463|M.smegmatis_MC2_155 RKVGTAVVRWPIPIILVTGLVAAIGFASLLTYVPQYNDQKFTPADMPANV
MAV_4755|M.avium_104 RKVGTAVVRWPKPIIVVTAAIAVIGFISLLTYVPNYDDQKFTPKDMPANA
*::*: :**** *:: : :: :*: :* * ..*..: : * *:*
Mb0458c|M.bovis_AF2122/97 GYAAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGIS
Rv0450c|M.tuberculosis_H37Rv GYAAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGIS
MLBr_02378|M.leprae_Br4923 GFAAADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGIS
Mflv_3435|M.gilvum_PYR-GCK GYAVADEHFDQARMNPELLMIESDHDLRNSADFLVIDKIAKALFRVEGIA
Mvan_3189|M.vanbaalenii_PYR-1 GYAVADRHFDQARMNPELLMIESDHDLRNSADFLVIDKIAKAIFKVEGIA
TH_3260|M.thermoresistible__bu GYEAAERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEGIS
MUL_0757|M.ulcerans_Agy99 GYSAAERHFSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGIS
MMAR_0775|M.marinum_M GYTAADRHFSQARMNPELLMVETDHDMRNPADMLVIDRIAKGVFHLPGVA
MAB_4310c|M.abscessus_ATCC_199 AMEVADRHFSQARMNPELLMLEADHDLRTPADMLVIDRVAKGIVHMRGIE
MSMEG_0463|M.smegmatis_MC2_155 AMAVADRHFSEARMNPELLMLEADHDIRNPADMLVIDRVAKYVVHMRGIE
MAV_4755|M.avium_104 AMTAAERHFSQARMNPELLMVEADHDLRDPADMLVVDRIAKSVFHLRGIE
. .*:.** **::**:*::*:***:* .:*:*:::::*: :. : *:
Mb0458c|M.bovis_AF2122/97 RVQAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEM
Rv0450c|M.tuberculosis_H37Rv RVQAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEM
MLBr_02378|M.leprae_Br4923 RVQAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENM
Mflv_3435|M.gilvum_PYR-GCK RVQAITRPDGKPIKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLVQADEM
Mvan_3189|M.vanbaalenii_PYR-1 RVQAITRPDGKPIKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLVQADEM
TH_3260|M.thermoresistible__bu RVQGITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADEM
MUL_0757|M.ulcerans_Agy99 RVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDI
MMAR_0775|M.marinum_M RVQAVTRPLGKPIEHSSIPFQISMQNTVQVENMQYMKQRMADMLIQAAAM
MAB_4310c|M.abscessus_ATCC_199 RVQTITRPLGAPIEHSSIPFLMGAQNAGTLQTAKFNNENSAQMLEQADEL
MSMEG_0463|M.smegmatis_MC2_155 RVQTITRPLGSPIEHSSIPFLLGAQNAGTMQAAKFNNDNTAQMLEQADEL
MAV_4755|M.avium_104 RVQTITRPLGAPIEHSSIPFQIAMQNSGTLQTAKFMNDTMANMLEQADEL
*** :*** * .:.*:**** :. *.: :: .: .:* *. :
Mb0458c|M.bovis_AF2122/97 ATTIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWR
Rv0450c|M.tuberculosis_H37Rv ATTIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWR
MLBr_02378|M.leprae_Br4923 AETIASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWR
Mflv_3435|M.gilvum_PYR-GCK ANTIKTMEKMSGLTAQMADITHSMVTKMEGMVVDIEDLRDSIANFDDFFR
Mvan_3189|M.vanbaalenii_PYR-1 ANTIATMEKMSNLTAQMADITHSMVSKMENMLTDIEDLRDSIANFDDFFR
TH_3260|M.thermoresistible__bu QLMIDTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFFR
MUL_0757|M.ulcerans_Agy99 QTNIDQMERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFR
MMAR_0775|M.marinum_M QDSIDTLDRMYDIMGKMVETTHDMDGLTHDMVEITDELRDHIADFDDFWR
MAB_4310c|M.abscessus_ATCC_199 SRTVASMERMYSLMQELTGTMHSMVGRTHEMEATIQEMRDNLANFDDFFR
MSMEG_0463|M.smegmatis_MC2_155 SRTIASMERMYGLTQELTDTTHSMVGRTHDMVEATKEMRDSLADFDDFFR
MAV_4755|M.avium_104 DKTIAVMEHMYGVMKELTATTHSMVGRTHEMVDTTNELRDRIADFDDFFR
: : :* : :. . : * .:*: :::****:*
Mb0458c|M.bovis_AF2122/97 PIRSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDR
Rv0450c|M.tuberculosis_H37Rv PIRSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDR
MLBr_02378|M.leprae_Br4923 PIRSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDL
Mflv_3435|M.gilvum_PYR-GCK PIRNYFYWEPHCYNIPVCWALRSVFDTLDGINIMTDDFKAIIPDMKRLDT
Mvan_3189|M.vanbaalenii_PYR-1 PIRNYFYWEPHCYNIPVCWALRSVFDTLDGINVMTDDFREILPDMKRLDS
TH_3260|M.thermoresistible__bu PIRNYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLND
MUL_0757|M.ulcerans_Agy99 PIRSYFYWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDT
MMAR_0775|M.marinum_M PIRSYFYWEKHCYDVPICWSLRSIFDALDGVDKITEKLAALSRDMDRLDI
MAB_4310c|M.abscessus_ATCC_199 PLRNYFYWEKHCFDIPICQSLRSIFDVLDSVDVLADQMHGLIADMDHMDQ
MSMEG_0463|M.smegmatis_MC2_155 PMRNYLYWEPHCYDIPVCQSLRSVFDTLDGIGQLTDEMQGLTIDMDRMDE
MAV_4755|M.avium_104 PIRSYFYWEKHCFDIPVCWSMRSLFDALDGIDELSDQISGLTIDLDHMDR
*:*.*:*** **:.:*:* ::**:**.**.:. : : : : : .::
Mb0458c|M.bovis_AF2122/97 LMPQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKA
Rv0450c|M.tuberculosis_H37Rv LMPQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKA
MLBr_02378|M.leprae_Br4923 LMPQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKA
Mflv_3435|M.gilvum_PYR-GCK LMPQMVALMPEMIETMKTMRTMMLTMYQSQKGQQDQMAAMSEDADAMGEA
Mvan_3189|M.vanbaalenii_PYR-1 LMPQMVALMPEMIETMKTMRTMMLTMYQSQKGQQDQMAAMSEDADAMGEA
TH_3260|M.thermoresistible__bu LMPQMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMGEA
MUL_0757|M.ulcerans_Agy99 LMPQMTAMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEA
MMAR_0775|M.marinum_M LMPQMRAQIPFQIASMKTMKTMMLTMHSSMSSLYDQMDEMSKNSTAMGKA
MAB_4310c|M.abscessus_ATCC_199 LMPQMLPVLRTTIDSMGRMRDFMIATHSTMAGTQAQQQELAKGATEIGLY
MSMEG_0463|M.smegmatis_MC2_155 LMPQMLPILRSTIDSMKTMRDFMIATHSVMAGTQAQQQELAKNATEIGLY
MAV_4755|M.avium_104 LMPQLLADFPKTIDSMKTMRDFMLSTHSTMAGIQAHQQEAAEGSTLMGQY
****: : : :* *: ::: . : ..: :*
Mb0458c|M.bovis_AF2122/97 FDAAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSP
Rv0450c|M.tuberculosis_H37Rv FDAAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSP
MLBr_02378|M.leprae_Br4923 FDTAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASV
Mflv_3435|M.gilvum_PYR-GCK FDDSMNDDSFYLPPEIFENADFQRGLEQFLSPDGHAVRFIISHEGDPLSP
Mvan_3189|M.vanbaalenii_PYR-1 FDDSMNDDSFYLPPEIFENKDFQRGLEQFLSPDGHAVRFIISHEGDPLSP
TH_3260|M.thermoresistible__bu FDQARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPMTP
MUL_0757|M.ulcerans_Agy99 FDSSRNDDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQ
MMAR_0775|M.marinum_M FDAARNDDSFYIPPEVFDNADFKRGLKMFLSPDGHAVRFIISHEGDPAST
MAB_4310c|M.abscessus_ATCC_199 FDQAKNDDFFYLPPDVFTNPDFKRGLKMFVSPDGKAVRFIITHQGDPASV
MSMEG_0463|M.smegmatis_MC2_155 FDQAKNDDFFYLPPDVFDNPDFKRGLEMFVSPDGKAVRMIITHQGDPASV
MAV_4755|M.avium_104 FDEAKNDDSFYLPPEVFKNPDFKRGLKMFVSPDGTAVRFIITHQGDPASV
** : *** **:**: * * **:*.:: *:*.** *.*:** *.*** :
Mb0458c|M.bovis_AF2122/97 EGIKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIA
Rv0450c|M.tuberculosis_H37Rv EGIKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIA
MLBr_02378|M.leprae_Br4923 AGIASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIA
Mflv_3435|M.gilvum_PYR-GCK EGVAKIDKIKTAAKEAVKGTPLEGSKIYLGGTAAVFKDMQDGNNYDLLIA
Mvan_3189|M.vanbaalenii_PYR-1 EGVAKIDKIKTAAKEAIKGTPLEGSKIYLGGTAATFKDMQDGNNYDLLIA
TH_3260|M.thermoresistible__bu EGLAKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLIIA
MUL_0757|M.ulcerans_Agy99 AGINHIDKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIA
MMAR_0775|M.marinum_M EGISHVKPIMDEAKQAIKGTPLEGAKIYLAGTASVYKDMRDGSRWDLLIA
MAB_4310c|M.abscessus_ATCC_199 EGIDHVRDLKGVVADAVKGTPLSNAKVSIAGTASMYADMQDGVSIDLMIA
MSMEG_0463|M.smegmatis_MC2_155 DGIAHVRDLRDVVADAVKGTPLANAKVSLAGTASLYSDMQDGVVTDLMIA
MAV_4755|M.avium_104 EGIKHVAGVKDAVADAIKGTPLESSKVYLAGTASMYSDMQEGVIIDLLVA
*: : : . :::***** .: : :.**.: : *: :* **::*
Mb0458c|M.bovis_AF2122/97 AISSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAI
Rv0450c|M.tuberculosis_H37Rv AISSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAI
MLBr_02378|M.leprae_Br4923 GISSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGI
Mflv_3435|M.gilvum_PYR-GCK GIAALGLIFIIMLILTRAVVAAAVIVGTVVLSLAASFGLSVLFWQHILGQ
Mvan_3189|M.vanbaalenii_PYR-1 GISALGLIFIIMLILTRAIVAAAVIVGTVVLSLAASFGLSVLFWQHILGT
TH_3260|M.thermoresistible__bu AIAAVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIVGL
MUL_0757|M.ulcerans_Agy99 GISALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGI
MMAR_0775|M.marinum_M GVAAVSLILIIMLIITRSLVAAVVIVGTVLLSLGASFGLSVLVWQDIFGV
MAB_4310c|M.abscessus_ATCC_199 VIASMILIFAIMVLITRSVVAALVIVGTVAASLGTACGLSVLLWQDILGL
MSMEG_0463|M.smegmatis_MC2_155 IIASMILIFGIMLVITRSVVAALVIVGTVAASLGTACGLSVLLWQDILGL
MAV_4755|M.avium_104 GISCLILIFTIMLIITRSVVAALVIVGTVAASLGTACGLSVLMWQDLIGL
::.: **: **:::**:.:** ****** **.:: *:***.** :..
Mb0458c|M.bovis_AF2122/97 HLHWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGK
Rv0450c|M.tuberculosis_H37Rv HLHWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGK
MLBr_02378|M.leprae_Br4923 ELHYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGK
Mflv_3435|M.gilvum_PYR-GCK PLHWMVLAMAVIILLAVGADYNLLLVSRLKEEIHAGIGTGIIRAMGGSGS
Mvan_3189|M.vanbaalenii_PYR-1 ELHWMVLAMAVIVLLAVGADYNLLLVSRLKEEIHAGIGTGIIRAMGGSGS
TH_3260|M.thermoresistible__bu EMHWMVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGSGS
MUL_0757|M.ulcerans_Agy99 ELHWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGS
MMAR_0775|M.marinum_M ELHWMVLAMSVILLLAVGSDYNLLLVSRLKEEIGAGLKTGIIRAMAGTGG
MAB_4310c|M.abscessus_ATCC_199 GVQWIVIPLSMVILLAVGSDYNLLVVSRLKEEIHAGLNTGMIRGMGATGR
MSMEG_0463|M.smegmatis_MC2_155 GVQWVVLPLSIVILLAVGSDYNLLLVSRLKEEIHAGLNTGIIRGMGATGR
MAV_4755|M.avium_104 GVQWIVLPLSIVILLAVGSDYNLLLVSRLKEEIPAGLNTGIIRGMGASGR
::::*:.:::::*****:*****:*:*:::** **: **:**.*..:*
Mb0458c|M.bovis_AF2122/97 VVTNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSI
Rv0450c|M.tuberculosis_H37Rv VVTNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSI
MLBr_02378|M.leprae_Br4923 VVTNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSI
Mflv_3435|M.gilvum_PYR-GCK VVTAAGLVFALTMMSMSVSELTVIGQVGTTIGLGLLFDTLVIRAFMTPSI
Mvan_3189|M.vanbaalenii_PYR-1 VVTAAGLVFALTMMSMAVSELTVIGQVGTTIGLGLLFDTLVIRAFMTPSI
TH_3260|M.thermoresistible__bu VVTAAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMPSI
MUL_0757|M.ulcerans_Agy99 VVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSI
MMAR_0775|M.marinum_M VVTTAGLVFAATMASFIFSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSI
MAB_4310c|M.abscessus_ATCC_199 VVTAAGLVFAFTMMSMIVSDLRVVGQLGMTIGIGLIVDTLIVRAFMTPSI
MSMEG_0463|M.smegmatis_MC2_155 VVTAAGLVFAFTMMAMIVSDLRVVGQLGTTIGLGLIVDTLIVRAFMTPSI
MAV_4755|M.avium_104 VVTAAGLVFAFTMASMIVSQLRVIGELGTTIALGLLVDTLIVRSFMTPSI
*** *****. ** : .*:* *:.::* **.:**:.**:::*:** ***
Mb0458c|M.bovis_AF2122/97 AALLGRWFWWPL-----RVRSRPARTPTVPSETQPAGRPLAMSSDRLG--
Rv0450c|M.tuberculosis_H37Rv AALLGRWFWWPL-----RVRSRPARTPTVPSETQPAGRPLAMSSDRLG--
MLBr_02378|M.leprae_Br4923 AALLGRWFWWPQ-----QGRTRPLLTVAAPVGLPPD-RSLVYSD------
Mflv_3435|M.gilvum_PYR-GCK AALLGPWFWWPQ-----RVRTRPVPAPWPRSGGLQSDPSEGVRA------
Mvan_3189|M.vanbaalenii_PYR-1 AALLGPWFWWPQ-----RVRTRPVPAPWPRPGGLQSDPSEGVKV------
TH_3260|M.thermoresistible__bu ATLLGRWFWWPQ-----FVRKRPVPQPWPSVPPRGPATTDRVSV------
MUL_0757|M.ulcerans_Agy99 AALLGKWFWWPQ-----VVRQRPAPQPWPTPAPTPPPATTSV--------
MMAR_0775|M.marinum_M AALMGRWFWWPQ-----QVRTRPASQLLRPYGPRPLVRALLLPRNGDSAD
MAB_4310c|M.abscessus_ATCC_199 AAALGRWFWWPINVFEIVRRGRETQAPEPVTAPLPVVDAGPQPPTAPSTS
MSMEG_0463|M.smegmatis_MC2_155 AAALGRWFWWPLNTFEITRRGR--QAPHARS-----VDGNTQPFPGVTTA
MAV_4755|M.avium_104 AAALGHWFWWPINTIRMTRRTHHDEEAHTAP--------IRQPALR----
*: :* ***** * :
Mb0458c|M.bovis_AF2122/97 -----------------
Rv0450c|M.tuberculosis_H37Rv -----------------
MLBr_02378|M.leprae_Br4923 -----------------
Mflv_3435|M.gilvum_PYR-GCK -----------------
Mvan_3189|M.vanbaalenii_PYR-1 -----------------
TH_3260|M.thermoresistible__bu -----------------
MUL_0757|M.ulcerans_Agy99 -----------------
MMAR_0775|M.marinum_M GPEDTNTERLAVSSPHY
MAB_4310c|M.abscessus_ATCC_199 -----------------
MSMEG_0463|M.smegmatis_MC2_155 P----------------
MAV_4755|M.avium_104 -----------------