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M. abscessus ATCC 19977 MAB_4104 (-)

annotation: putative glycosyltransferase GtfB
coordinates: 4163464 - 4164717
length: 417

MKFALACYGTRGDVEPSVSVGCELSRRGHDVSIAVPPELIGFAESAGLAAVPYGPKLHDFLQDEFLRTFW
TRLMRNPIGALRELWAPIARYWPDTSTTLLSLAEDADLLSTGLNFEQSAGNVAEYFDIPLIMLHHFPMRP
NGQLLPMLPARLVRSGGLLSEWLLWRATKDADDAQREVLGLPRATRPSAFRTARRGAVEIQAYDAVSVPG
LAMEWAKWGDSRPFVGALTMGLTTGADQDVAAWLAAGKPPICFATGSIPLESPSDTVEMISSACAELGER
GLICAGGTDFSEITIPDHVKVVGAVNYAAVFAASRAVVHHGGSGTTAASLRAGVPTLILWSSADQPYWGN
QLSRLKVGAARRFSATDRNTLAADLRRVLLPEYAVAARAVSAQMTSPTDSVTKAADLFESTAGRKAV
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_4104--100% (417)putative glycosyltransferase GtfB
M. abscessus ATCC 19977MAB_4112c-e-14460.53% (418) putative glycosyltransferase GtfA
M. abscessus ATCC 19977MAB_4107c-e-12856.46% (418) glycosyltransferase GtfA

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1551-1e-12354.44% (417) glycosyltransferase
M. gilvum PYR-GCKMflv_0466-3e-0823.17% (341) glycosyl transferase family protein
M. tuberculosis H37RvRv1524-1e-12354.44% (417) glycosyltransferase
M. leprae Br4923MLBr_02348-1e-12053.96% (417) putative glycosyl transferase
M. marinum MMMAR_2353-1e-11650.85% (411) UDP-glycosyltransferase
M. avium 104MAV_3258-1e-16166.43% (417) glycosyltransferase family protein 28
M. smegmatis MC2 155MSMEG_0392-1e-16867.15% (417) glycosyl transferase
M. thermoresistible (build 8)TH_1989-4e-5470.42% (142) Glycosyltransferase family protein 28
M. ulcerans Agy99MUL_4949-6e-9547.70% (413) glycosyltransferase
M. vanbaalenii PYR-1Mvan_1905-2e-0823.53% (425) glycosyl transferase family protein

CLUSTAL 2.0.9 multiple sequence alignment


MAB_4104|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0392|M.smegmatis_MC2_155      MFSLHATRSRASTNAFPRAIFEVSRTTRERTTRTEKFSDCDARQHLCPAQ
TH_1989|M.thermoresistible__bu      --------------------------------------------------
MAV_3258|M.avium_104                --------------------------------------------------
Mb1551|M.bovis_AF2122/97            --------------------------------------------------
Rv1524|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02348|M.leprae_Br4923          --------------------------------------------------
MMAR_2353|M.marinum_M               --------------------------------------------------
MUL_4949|M.ulcerans_Agy99           --------------------------------------------------
Mflv_0466|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1905|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

MAB_4104|M.abscessus_ATCC_1997      -------------------------------------MKFALACYG-TRG
MSMEG_0392|M.smegmatis_MC2_155      EPVAAREAIPPNLTRYGPLRAGWAIIPAHANPRGLIRMKFALACYG-TRG
TH_1989|M.thermoresistible__bu      --------------------------------------------------
MAV_3258|M.avium_104                -------------------------------------MRFALASYG-TRG
Mb1551|M.bovis_AF2122/97            -------------------------------------MKFVVASYG-TRG
Rv1524|M.tuberculosis_H37Rv         -------------------------------------MKFVVASYG-TRG
MLBr_02348|M.leprae_Br4923          -------------------------------------MKFTLAASG-SRG
MMAR_2353|M.marinum_M               -------------------------------------MKFALAING-TRG
MUL_4949|M.ulcerans_Agy99           -------------------------------------MKAVVASYG-SRG
Mflv_0466|M.gilvum_PYR-GCK          -------------------------------------MAVILAYTAPALG
Mvan_1905|M.vanbaalenii_PYR-1       -------------------------------------MATILAYTSPALG
                                                                                      

MAB_4104|M.abscessus_ATCC_1997      DVEPSVSVGCELSRRGHDVSIAVPPELIGFAESAGLAAVPYGP-KLHDFL
MSMEG_0392|M.smegmatis_MC2_155      DVEPSVAVGRELQRRGHEVCVAVPPGLVAFAETAGLDAVAYGP-ELDNFL
TH_1989|M.thermoresistible__bu      --------------------------------------------------
MAV_3258|M.avium_104                DIEPSAAVGRELLRRGHDVRLAVPPELVGFVESTGLAAVPYGP-NVQEFL
Mb1551|M.bovis_AF2122/97            DIEPCAAVGLELQRRGHDVCLAVPPNLIGFVETAGLSAVAYGSRDSQEQL
Rv1524|M.tuberculosis_H37Rv         DIEPCAAVGLELQRRGHDVCLAVPPNLIGFVETAGLSAVAYGSRDSQEQL
MLBr_02348|M.leprae_Br4923          DVEPFAALGLELQRRGHEVRIGVPPDMLRFVESAGLAAVAYGP-DTQEFL
MMAR_2353|M.marinum_M               DVEPCAALGRELSRRGHEVRVAVPPNLTGLAAAAGLEAVPYGP-DTDELL
MUL_4949|M.ulcerans_Agy99           DVEPCAAAARELLRRGHEVRVAAPPNLVGFLESAGLTTVAYGP-DSHQQM
Mflv_0466|M.gilvum_PYR-GCK          HLFPFCAVLQELARRGHDIHVRTLAAGLQICRDEGFTAAAVDP-RIEAIQ
Mvan_1905|M.vanbaalenii_PYR-1       HLLPMGALLSELSRRGHTVHLRTLSSGLDHARGLGVSVEPIDP-RIEAIE
                                                                                      

MAB_4104|M.abscessus_ATCC_1997      QDE---FLRTFWTRLMRNPIGALRELWAPIARYWPDTSTTLLSLAEDADL
MSMEG_0392|M.smegmatis_MC2_155      RDD---FLRNFWMQMIRNPVGSLRELWAPITRYWNDTSKVLTTLADGADL
TH_1989|M.thermoresistible__bu      --------------------------------------------------
MAV_3258|M.avium_104                DEE---FLRNMWRDFFRNPIRLVLKVWDPIIKYWAEASATLKSVAEGADL
Mb1551|M.bovis_AF2122/97            DEQ---FLHNAWK--LQNPIKLLREAMAPVTEGWAELSAMLTPVAAGADL
Rv1524|M.tuberculosis_H37Rv         DEQ---FLHNAWK--LQNPIKLLREAMAPVTEGWAELSAMLTPVAAGADL
MLBr_02348|M.leprae_Br4923          ARDTYSQWRQWWK--ILPPIKALQQ----LRQAWADMATDLKSLADGADL
MMAR_2353|M.marinum_M               NDE--DNLQEFWK--PQTSIKLVREGISDLRQAWSDMAGTLKTLADGADL
MUL_4949|M.ulcerans_Agy99           GPAP--NLVGDLAATAQHPITMVPKLIEHLTRVNAAKSETLTALADGADL
Mflv_0466|M.gilvum_PYR-GCK          ADD------TLTG-TVRAAADTVEVLTARAPLEVADLLSAVESVQP--DV
Mvan_1905|M.vanbaalenii_PYR-1       LDD------WKASNPVGALKLSIGAFGRRASYEIADLGKALTTVQP--DG
                                                                                      

MAB_4104|M.abscessus_ATCC_1997      LSTGLNFEQSAGNVAEYFDIPLIMLH-HFPMRPNGQLLP--MLPARLVRS
MSMEG_0392|M.smegmatis_MC2_155      LSTGINFEQAAANVAEHYDIPFVSLH-HFPMRPNGKLVP--ALPASVVRS
TH_1989|M.thermoresistible__bu      --------------------------------------------------
MAV_3258|M.avium_104                LSTGLNFEQAAANVAEYYDIPLASLH-HFPMRANGQLVP--NMPSPLVRS
Mb1551|M.bovis_AF2122/97            LLTGQIYQEVVANVAEHHGIPLAALH-FYPVRANGEIAFPARLPAPLVRS
Rv1524|M.tuberculosis_H37Rv         LLTGQIYQEVVANVAEHHGIPLAALH-FYPVRANGEIAFPARLPAPLVRS
MLBr_02348|M.leprae_Br4923          VMTGVVYQGVVANVAEYYGIPFGVLH-FVPARVNGKIIP--SLPSPLNRA
MMAR_2353|M.marinum_M               VLTGMIHQGIALNAAEYYGIPLATMH-FLPSRVNSRVIP--ILSPRLNRS
MUL_4949|M.ulcerans_Agy99           LVVGFNEQAVAANVAEYFGIPLAGLH-FFPAP---------ALPAGMLST
Mflv_0466|M.gilvum_PYR-GCK          VIVDANCWGAMS-VAETLGRPWVVLSPFTPYLRSPGAPPFGPGATPWPGP
Mvan_1905|M.vanbaalenii_PYR-1       VLVDVNCWGAHS-AVEATGVPWASFAPYTPALTVAGVPPFGLGLKPMSGP
                                                                                      

MAB_4104|M.abscessus_ATCC_1997      GGLLSEWLLWRATKDADDAQREVLGLPRATRPSAFRTARRGAVEIQAYDA
MSMEG_0392|M.smegmatis_MC2_155      VGALSEWLFWRSTKEVEDAQRRELGLPRTKVPSPRRIAERGSLEIQAYDA
TH_1989|M.thermoresistible__bu      --------------------------------------------------
MAV_3258|M.avium_104                TMTAIEWLFWRSTKKVDNAQRRQLGLPKATRRSQRRIAERGWLEIQAYDE
Mb1551|M.bovis_AF2122/97            TITAIDWLYWRMTKGVEDAQRRELGLPKASTPAPRRMAVRGSLEIQAYDA
Rv1524|M.tuberculosis_H37Rv         TITAIDWLYWRMTKGVEDAQRRELGLPKASTPAPRRMAVRGSLEIQAYDA
MLBr_02348|M.leprae_Br4923          ILATVWRAHWLLAKKPEDAQRRELGLPKATSLSTRRIVKRGALEIQAYDE
MMAR_2353|M.marinum_M               VISALWWVHWRVTKNPEEAQRRELGMAKASSSSTSRILKGRSLEIQAYDE
MUL_4949|M.ulcerans_Agy99           ----------LATKAADDAQRQALGLPPASESVPQRVAEQGSLEIQAYDQ
Mflv_0466|M.gilvum_PYR-GCK          LGRIRDWGIGLVTTAVFDRPFARQIAPLRRALGLTPVRTAGDLLLRAPAV
Mvan_1905|M.vanbaalenii_PYR-1       VGRLRDSVVRAGVSWPLERPAVAAINTVRSRVGLTPVGSLDQFLRRAPLL
                                                                                      

MAB_4104|M.abscessus_ATCC_1997      VSVPGLAMEWAKWGDSRPFVGALTMGLTTGADQDVAAWLAAGKPPICFAT
MSMEG_0392|M.smegmatis_MC2_155      VSVPGLADEWADQNRQRPFTGALTMSLSTEADDDVTSWITSGEPPICFAT
TH_1989|M.thermoresistible__bu      --------------------------------------------------
MAV_3258|M.avium_104                VCFPGLAAEWAHWGDRRPFVGALTMELPTESDDDVASWIAAGTPPICFGS
Mb1551|M.bovis_AF2122/97            LCFPGLAAEWG---GRRPFVGALTMESATDADDEVASWIAADTPPIYFGF
Rv1524|M.tuberculosis_H37Rv         LCFPGLAAEWG---GRRPFVGALTMESATDADDEVASWIAADTPPIYFGF
MLBr_02348|M.leprae_Br4923          LCFPGLAAEWAEYGDRRPFVGALTLELPTAADNEVLSWIAAGTPPIYFGF
MMAR_2353|M.marinum_M               LCFPGLAAEWAEWGDRRPFVGALTLEMPTESDNEVLSWIASGTPPIYFGF
MUL_4949|M.ulcerans_Agy99           IVLPGPPGRWVQADGRHPFIGALTLQSPTDDDDAILAWIAEGAPPIYFGF
Mflv_0466|M.gilvum_PYR-GCK          LVATGKPLEYP-HTDWGETVTMIGPAVFEPRAAQRPSWLDHIDDPIVLVT
Mvan_1905|M.vanbaalenii_PYR-1       FLATGTPFQY--AADWGENVHMIGPCAPEKAHGDAPDWLTAIDRPIVLVT
                                                                                      

MAB_4104|M.abscessus_ATCC_1997      GSIPLESPSDTVEMISSACAELGERGLICAGGTDFSEITIPDHVKVVGAV
MSMEG_0392|M.smegmatis_MC2_155      GSIPVQSPTATIEMISHACDQLGQRALVCAGGTDLRGVPQFDNVKMVGAV
TH_1989|M.thermoresistible__bu      -------------MFASVCSRLGERALICAGGTDIDGVPEYGHVKVVGAV
MAV_3258|M.avium_104                GSIPLESPTATVEMIGAASARLGERALICFGGTDVRGVPRFDHVKVVGPV
Mb1551|M.bovis_AF2122/97            GSMPIGSLADRVAMISAACAELGERALICSGPSDATGIPQFDHVKVVRVV
Rv1524|M.tuberculosis_H37Rv         GSMPIGSLADRVAMISAACAELGERALICSGPSDATGIPQFDHVKVVRVV
MLBr_02348|M.leprae_Br4923          GSMPIVSPTDTVAMIAAACADLGERALISVKPKDLTQVPKFDHVKIVTSV
MMAR_2353|M.marinum_M               GSMPVESPAATIAMISAACAELGERALICTGSNDLGGLQAPENVKLVSGV
MUL_4949|M.ulcerans_Agy99           GSTPLTSPAEQFAMISAACAQLGERALICAGPNDFGQMPHSHQVMVAPAV
Mflv_0466|M.gilvum_PYR-GCK          TSSVGQSDAALVETAVEALRDE-PVHLVVTAPTGDVDVMTRPGVTQVRFA
Mvan_1905|M.vanbaalenii_PYR-1       TSSERQGDAGLVSAAVDALTDE-PVHVVATLPAGVDQVPGSAHATILRFV
                                                     .        ::     .   :     .     .

MAB_4104|M.abscessus_ATCC_1997      NYAAVFAASRAVVHHGGSGTTAASLRAGVPTLILWSSADQPYWGNQLSRL
MSMEG_0392|M.smegmatis_MC2_155      NYAAVFPLCRGIVHHGGSGTTAASLRAGVPTLILWSTADQPYWGNQLKRL
TH_1989|M.thermoresistible__bu      NYARVFPACRAIVHHGGSGTTAAVLRAGVPSLVTWSSADQPYWGNQVKRL
MAV_3258|M.avium_104                NYASVFPACRAVVHHGGSGTTAASLRAGIPTLALWSSADQPYWAAQIKRL
Mb1551|M.bovis_AF2122/97            SHAAVFPTCRAVVHHGGAGTTAAGLRAGIPTLILWVTSDQPIWAAQIKQL
Rv1524|M.tuberculosis_H37Rv         SHAAVFPTCRAVVHHGGAGTTAAGLRAGIPTLILWVTSDQPIWAAQIKQL
MLBr_02348|M.leprae_Br4923          SHAAVFPACRAVVHHGGAGTTAASLRAGVPTLILWIFIEQPVWAAQIKRL
MMAR_2353|M.marinum_M               SHAAVFPACRAVVHHGGAGTTAAGMRAGIPTLILWIWIEQPIWLAQIKRL
MUL_4949|M.ulcerans_Agy99           NHAAVFPACRAIVHHGGAGTTAAGLRAGIPMLIRWLWLDQPIWAAGIEEL
Mflv_0466|M.gilvum_PYR-GCK          PHSMLLEHAVCVITHGGMGVTQKALARGVPVCVVPFGRDQFEVARRVELA
Mvan_1905|M.vanbaalenii_PYR-1       DHDLVLGRAVCAVTHGGMGATQRALARGVPVCVVPYGRDQFEVARRAEVA
                                     :  ::  .   : *** *.*   :  *:*        :*       .  

MAB_4104|M.abscessus_ATCC_1997      KVGAARRFSATDRNTLAADLRRVLLPEYAVAARAVSAQMTSPTDSVTKAA
MSMEG_0392|M.smegmatis_MC2_155      KVGTSRRFSGASRKSLVTDLRRILRPEYAVRARELAMRMTPAAESVTIAA
TH_1989|M.thermoresistible__bu      KVGTSRRFSHTTPDTLVADLRRILTPDYAVRARAVAARMTDPADSVVRAA
MAV_3258|M.avium_104                KVGTARRFSATTSETLAADLRTILAPDYATRARDLAARMTKPAESIETTA
Mb1551|M.bovis_AF2122/97            KVGRGRRFSSATKESLIADLRTILAPDYVTRAREIASRMTKPAASVTATA
Rv1524|M.tuberculosis_H37Rv         KVGRGRRFSSATKESLIADLRTILAPDYVTRAREIASRMTKPAASVTATA
MLBr_02348|M.leprae_Br4923          KVGAGRRFSATTQRSLAADLRTILAPQYATRAREVANRMSKPDESVNAAA
MMAR_2353|M.marinum_M               KIGSGRRLASTTKETLVSDLRCILGPDYVARARTIANEMSKPGESATRAA
MUL_4949|M.ulcerans_Agy99           GVGVGQPFSAATSESLAAGLGSILAAQYIARARTVADQMTPPAHSIAMAA
Mflv_0466|M.gilvum_PYR-GCK          GCGTRLPAGKLSVGRLRTAVKTAAT--MTGGAARVAAGFAATG-GVARGA
Mvan_1905|M.vanbaalenii_PYR-1       RCGTRLPAKRLSAPRLRNKIREAMG--LTSGARAVADGFAATG-GVARGA
                                      *            *   :           *  ::  :: .  .    *

MAB_4104|M.abscessus_ATCC_1997      DLFESTAGRKAV-------
MSMEG_0392|M.smegmatis_MC2_155      DLYENAVRQAAM-------
TH_1989|M.thermoresistible__bu      DLFETAVECAPGVAHRE--
MAV_3258|M.avium_104                DLLEEAARRKTLG------
Mb1551|M.bovis_AF2122/97            DLLEDAARRAR--------
Rv1524|M.tuberculosis_H37Rv         DLLEDAARRAR--------
MLBr_02348|M.leprae_Br4923          DLLEDKASRNKSRTRYQDC
MMAR_2353|M.marinum_M               DLLENEVSVS---------
MUL_4949|M.ulcerans_Agy99           DLLEHTAHVDRRS------
Mflv_0466|M.gilvum_PYR-GCK          DVVESRLVARCALPEEQ--
Mvan_1905|M.vanbaalenii_PYR-1       DLFEHLVGGN---------
                                    *: *