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AVILAYTAPALGHLFPFCAVLQELARRGHDIHVRTLAAGLQICRDEGFTAAAVDPRIEAIQADDTLTGTV RAAADTVEVLTARAPLEVADLLSAVESVQPDVVIVDANCWGAMSVAETLGRPWVVLSPFTPYLRSPGAPP FGPGATPWPGPLGRIRDWGIGLVTTAVFDRPFARQIAPLRRALGLTPVRTAGDLLLRAPAVLVATGKPLE YPHTDWGETVTMIGPAVFEPRAAQRPSWLDHIDDPIVLVTTSSVGQSDAALVETAVEALRDEPVHLVVTA PTGDVDVMTRPGVTQVRFAPHSMLLEHAVCVITHGGMGVTQKALARGVPVCVVPFGRDQFEVARRVELAG CGTRLPAGKLSVGRLRTAVKTAATMTGGAARVAAGFAATGGVARGADVVESRLVARCALPEEQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0466 | - | - | 100% (414) | glycosyl transferase family protein |
| M. gilvum PYR-GCK | Mflv_2592 | - | 5e-35 | 29.93% (431) | glycosyl transferase family protein |
| M. gilvum PYR-GCK | Mflv_3984 | - | 3e-24 | 28.82% (406) | UDP-glucuronosyl/UDP-glucosyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2759c | - | 3e-29 | 29.72% (397) | alanine rich transferase |
| M. tuberculosis H37Rv | Rv2739c | - | 3e-29 | 29.72% (397) | alanine rich transferase |
| M. leprae Br4923 | MLBr_00985 | - | 8e-30 | 30.45% (358) | putative glycosyltransferase |
| M. abscessus ATCC 19977 | MAB_3062c | - | 5e-29 | 29.62% (395) | hypothetical protein MAB_3062c |
| M. marinum M | MMAR_1974 | - | 1e-29 | 29.77% (393) | glycosyl transferase |
| M. avium 104 | MAV_3631 | - | 2e-32 | 31.30% (393) | hypothetical protein MAV_3631 |
| M. smegmatis MC2 155 | MSMEG_2342 | - | 1e-123 | 54.43% (406) | putative glycosyltransferase |
| M. thermoresistible (build 8) | TH_3465 | - | 3e-20 | 30.98% (397) | PUTATIVE UDP-glucuronosyl/UDP-glucosyltransferase |
| M. ulcerans Agy99 | MUL_3383 | - | 9e-30 | 29.77% (393) | glycosyl transferase |
| M. vanbaalenii PYR-1 | Mvan_1905 | - | 1e-114 | 53.48% (402) | glycosyl transferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0466|M.gilvum_PYR-GCK ------------------------MAVILAYTAPALGHLFPFCAVLQELA
Mvan_1905|M.vanbaalenii_PYR-1 ------------------------MATILAYTSPALGHLLPMGALLSELS
MSMEG_2342|M.smegmatis_MC2_155 ------------------------MATILAYTSPALGHVYPLAALLTELA
MMAR_1974|M.marinum_M -------------------------MRVAVVAGPDPGHSFPAIALCRRFL
MUL_3383|M.ulcerans_Agy99 -------------------------MRVAVVAGPDPGHSFPAIALCRRFL
MAV_3631|M.avium_104 -------------------------MRVAVVAGPDPGHSFPAIALCRRFA
Mb2759c|M.bovis_AF2122/97 -------------------------MRVAVVAGPDPGHSFPAIALCQRFR
Rv2739c|M.tuberculosis_H37Rv -------------------------MRVAVVAGPDPGHSFPAIALCQRFR
MLBr_00985|M.leprae_Br4923 ---------------------MVHYMRVAVVAGPDPGHSFPAIALCQRFA
MAB_3062c|M.abscessus_ATCC_199 -------------------------MRVAVVAGPDPGHAFPALALCLKFA
TH_3465|M.thermoresistible__bu VGGYGLTRTRLLGRRLSSGSEDEFLARYLLAATPLSGHVAPLVQIGATLR
: * ** * : :
Mflv_0466|M.gilvum_PYR-GCK RRGHDIHVRTLAAGLQICRDEGFTAAAVDPRIEAIQADDT---------L
Mvan_1905|M.vanbaalenii_PYR-1 RRGHTVHLRTLSSGLDHARGLGVSVEPIDPRIEAIELDDW---------K
MSMEG_2342|M.smegmatis_MC2_155 CRGHEIHLRTMAREVEAMRAAGFRADAVAPEIEAIRGDDR---------S
MMAR_1974|M.marinum_M AAGDIPTLLTGVEWLDTARAAGVDAIELAGLVA--TDEDL---------D
MUL_3383|M.ulcerans_Agy99 AAGDIPTLLTGVEWLDTARAAGVDAIELAGLVA--TDEDL---------D
MAV_3631|M.avium_104 DAGDTPTLFTGAEWLDTARGAGVDAVELDGLAA--TDEDV---------D
Mb2759c|M.bovis_AF2122/97 AAADTPTLFTGVEWLEAARAAGIDAVELDGLAA--TDRDL---------D
Rv2739c|M.tuberculosis_H37Rv AAADTPTLFTGVEWLEAARAAGIDAVELDGLAA--TDRDL---------D
MLBr_00985|M.leprae_Br4923 EAGDTPTLFTGVECVDIARAAGVETALLDGLVA--VDDDV---------D
MAB_3062c|M.abscessus_ATCC_199 AAGDDPVLLTGTRWLDQARAAGVESVELLGLQPRVDDDDA---------D
TH_3465|M.thermoresistible__bu SRGHTVTVLTTTEFADAVTRAGLRFTALPAGTAIDPPAAPPWWARYLPSQ
.. : * : *. :
Mflv_0466|M.gilvum_PYR-GCK TG-TVRAAADTVEVLTARAPLEVADLLSAVESVQPDVVIVDANCWGAM--
Mvan_1905|M.vanbaalenii_PYR-1 ASNPVGALKLSIGAFGRRASYEIADLGKALTTVQPDGVLVDVNCWGAH--
MSMEG_2342|M.smegmatis_MC2_155 TSDALEVLAMSLDVLCSRAASEVDDIRDAIARSRPDLVIVDANCWGAM--
MMAR_1974|M.marinum_M AG----------ARIHRRAAQMALLNAPALSDLAPDLVVSDVITACGG--
MUL_3383|M.ulcerans_Agy99 AG----------ARIHRRAAQMALLNAPALSDLAPDLVVSDVITACGG--
MAV_3631|M.avium_104 AG----------ARIHRRAARMAVLNVPALRDLAPDLVVSDVITAGGG--
Mb2759c|M.bovis_AF2122/97 AG----------ARIHRRAAQMAVLNVPRLRALEPELVVSDVITACGG--
Rv2739c|M.tuberculosis_H37Rv AG----------ARIHRRAAQMAVLNVPRLRALEPELVVSDVITACGG--
MLBr_00985|M.leprae_Br4923 AG----------ARIHRRAAQMAVLNVPVLRDLAPDLIVSDVITAAGG--
MAB_3062c|M.abscessus_ATCC_199 SG----------AKIHQRAAHMALANLDQLRALAPDLIVSDVITACGG--
TH_3465|M.thermoresistible__bu ARRFLLGRAELDSVYIRPLGHQAAALRSVLDREPADAVLVDMTFTGAAAL
: : .: :: * .
Mflv_0466|M.gilvum_PYR-GCK SVAETLGRPWVVLSPFTPYLRSPGAPPFGPGATPWPGPLGR----IRDWG
Mvan_1905|M.vanbaalenii_PYR-1 SAVEATGVPWASFAPYTPALTVAGVPPFGLGLKPMSGPVGR----LRDSV
MSMEG_2342|M.smegmatis_MC2_155 AAAEAEGLPWAVFSPFTPYLRSRGVPPFGPGLRPWPGLPGR----ARDAL
MMAR_1974|M.marinum_M MAAERLGIPWIELNPHPLYRPSKGLPPIGSGLAPGTGIRGR----LRDTT
MUL_3383|M.ulcerans_Agy99 MAAERLGIPWIELNPHPLYRPSKGLPPIGSGLAPGTGIRGR----LRDTT
MAV_3631|M.avium_104 MAAELLGIPWIELSPHPLYLPSKGLPPIGSGLATGTGLRGR----LRDAT
Mb2759c|M.bovis_AF2122/97 MAAELLGIPWVELNPHPLYLPSKGLPPIGSGLAAGTGIRGR----LRDAT
Rv2739c|M.tuberculosis_H37Rv MAAELLGIPWVELNPHPLYLPSKGLPPIGSGLAAGTGIRGR----LRDAT
MLBr_00985|M.leprae_Br4923 MAAELLGIPWIELNPHPLYLPSKGLPPIGSGLASGVGIHGR----MRDAT
MAB_3062c|M.abscessus_ATCC_199 MAGELLGVPWVELNPHPLYLPSKGLPPLGSGLAPGVGLRGR----LRDGL
TH_3465|M.thermoresistible__bu LLDDRPRPPLLVCSVGPLTLSSADTPPFGMAWQPRPGVDYRGMTAVAHRV
: * . . **:* . . * * .
Mflv_0466|M.gilvum_PYR-GCK IGLVTTAVFDRPFARQIAPLRRALGLTPVRTAGDLLLRAPAVLVATGKPL
Mvan_1905|M.vanbaalenii_PYR-1 VRAGVSWPLERPAVAAINTVRSRVGLTPVGSLDQFLRRAPLLFLATGTPF
MSMEG_2342|M.smegmatis_MC2_155 MRRVTGRMFDDPVLRRMNPLRAEAGVPEVDSVDAMMRRAPLTLGVGGRPF
MMAR_1974|M.marinum_M MRALTARSWR-AGLRQRAAVRAEIGLAEHD------PGPLRRLIATLPAL
MUL_3383|M.ulcerans_Agy99 MRALTARSWR-AGLRQRAAVRAEIGLAEHD------PGPLRRLIATLPAL
MAV_3631|M.avium_104 MRALTARSWR-AGLRQRAAARAEIGLPARD------PGPLRRLIATLPAL
Mb2759c|M.bovis_AF2122/97 MRALTGRSWR-AGLRQRAAVRVEIGLPARD------PGPLRRLIATLPAL
Rv2739c|M.tuberculosis_H37Rv MRALTGRSWR-AGLRQRAAVRVEIGLPARD------PGPLRRLIATLPAL
MLBr_00985|M.leprae_Br4923 MRALTARSWR-AGLRERAAVRVQIGLPACD------SGPLRRLIATLPAL
MAB_3062c|M.abscessus_ATCC_199 MRRLTQKSID-QGLRQRSQARVEIGLPARD------PGPMRRLIATLPAL
TH_3465|M.thermoresistible__bu IMAGSRRRFD-RALRTAGAGPAPVFLSDWP------ALADRLIQLGVPGF
: :. . : :
Mflv_0466|M.gilvum_PYR-GCK EYPHTDWGETVTMIGPAVFEPRA-AQRPSWLDHIDDPIVLVTTSSVGQSD
Mvan_1905|M.vanbaalenii_PYR-1 QY-AADWGENVHMIGPCAPEKAH-GDAPDWLTAIDRPIVLVTTSSERQGD
MSMEG_2342|M.smegmatis_MC2_155 EYPHPDWGDSVHQLGACVFEPGP-VAEPPWLAEIDRPVVLVNTSSIAQAD
MMAR_1974|M.marinum_M EVPRPDWPAEAIVVGPLHFEPTD-QLLK--VPAGSGPVLVIAPSTALSGT
MUL_3383|M.ulcerans_Agy99 EVPRPDWPAEAIVVGPLHFEPTD-QLLK--VPAGSGPVLVIAPSTALSGT
MAV_3631|M.avium_104 EVPRPDWPDEAVLVGPLHFEPTD-RVLD--IPAGSGPVVVVAPSTAQTGA
Mb2759c|M.bovis_AF2122/97 EVPRPDWPAEAVVVGPLHFEPTD-RVLA--IPAGTGPVVVVAPSTALTGT
Rv2739c|M.tuberculosis_H37Rv EVPRPDWPAEAVVVGPLHFEPTD-RVLA--IPAGTGPVVVVAPSTALTGT
MLBr_00985|M.leprae_Br4923 EVSRPDWPAEAVVVGPLHFEPTD-RVLQ--IPSGSGPVIVVAPSTALTGI
MAB_3062c|M.abscessus_ATCC_199 EVPRPDWPAEAVVVGPLHWEPTD-VVLQ--PPSGSGPVVVIAPSTAFTGA
TH_3465|M.thermoresistible__bu EYHRGDLPSTVDFAGPVLPTGLDGVTLPAWWDDIRSAATVVHVTQGTFDN
: * . *. . :: :
Mflv_0466|M.gilvum_PYR-GCK AALVETAVEALRD-----EPVHLVVT-APTGDVD-VMTRPGVTQVRFAPH
Mvan_1905|M.vanbaalenii_PYR-1 AGLVSAAVDALTD-----EPVHVVAT-LPAGVDQ-VPGSAHATILRFVDH
MSMEG_2342|M.smegmatis_MC2_155 TILAHTALAAFAD-----EPVHVVAT-FPAGVPDGLPRPANATIGEYIPH
MMAR_1974|M.marinum_M AGLAEVALESLIPGDTLPSGSRLVVS-RLGGDDL---VTPSWAAVGLGSQ
MUL_3383|M.ulcerans_Agy99 AGLAEVALESLIPGGTLSSGSRLVVS-RLGGDDL---VTPSWAAVGLGSQ
MAV_3631|M.avium_104 RGLAEVALSCLTPGETLPAGARLVVS-RLAGPEL---AAPPWAVVGLGSQ
Mb2759c|M.bovis_AF2122/97 AGLTEVALQSLTPGETVPSGSRLVVS-RLSGADL---TVPPWAVAGLGSQ
Rv2739c|M.tuberculosis_H37Rv AGLTEVALQSLTPGETVPSGSRLVVS-RLSGADL---TVPPWAVAGLGSQ
MLBr_00985|M.leprae_Br4923 SGMAQTALDALVPGDTLPSGSRVVVS-RLNGPDL---TVPSWAVAGLVHQ
MAB_3062c|M.abscessus_ATCC_199 EGMTELAVQALES-----AGARVVIS-ALEPPSS---GLPSWAIAGLARQ
TH_3465|M.thermoresistible__bu TDLDQLVVPTLEALTDRPDVLVVATTGGRPGQRSGFRVPGNARVTGWLPY
: .: : :. :
Mflv_0466|M.gilvum_PYR-GCK SMLLEHAVCVITHGGMGVTQKALARGVPVCVVPFGRDQFEVARRVELAGC
Mvan_1905|M.vanbaalenii_PYR-1 DLVLGRAVCAVTHGGMGATQRALARGVPVCVVPYGRDQFEVARRAEVARC
MSMEG_2342|M.smegmatis_MC2_155 GVVLDRTVCVVTHGGMGTTLKALDRGIPVCVVPFARDQAEVARRVQMARC
MMAR_1974|M.marinum_M AELLTHADVVICGGGHGMVSKTLLAGVPLVVVPGGGDQWEIANRVVRQ--
MUL_3383|M.ulcerans_Agy99 AELLTHADVVICGGGHGMVSKTLLAGVPLVVVPGGGDQWEIANRVVRQ--
MAV_3631|M.avium_104 AELLRHADVVVCGGGHGMVAKTLLAGVPLVAVPGGGDQWEIANRVVRQ--
Mb2759c|M.bovis_AF2122/97 AELLTRADLVICGGGHGMVAKTLLAGVPMVVVPGGGDQWEIANRVVRQ--
Rv2739c|M.tuberculosis_H37Rv AELLTRADLVICGGGHGMVAKTLLAGVPMVVVPGGGDQWEIANRVVRQ--
MLBr_00985|M.leprae_Br4923 TKLLAHADVVICGGGHGMVAKTLLAGVPLVVVPGGGDQWEMANRVVRQ--
MAB_3062c|M.abscessus_ATCC_199 DLLLSGADLAVCGGGHGFLSKALLAGVPTVVVPGGGDQWELANRVVRQ--
TH_3465|M.thermoresistible__bu RMLMPHVDVMITNGGYGGVQYALSHGVPLIVAGETSDKAEIAARVEFCGA
:: . : ** * :* *:* .. *: *:* *.
Mflv_0466|M.gilvum_PYR-GCK GTRLPAGKLSVGRLRTAVKTAATMTGGAARVAAGFAATGGVARGADVVES
Mvan_1905|M.vanbaalenii_PYR-1 GTRLPAKRLSAPRLRNKIREAMGLTSGARAVADGFAATGGVARGADLFEH
MSMEG_2342|M.smegmatis_MC2_155 GTRLPAKHLSAARLRRKVRQAMAMSDGARRVAAGFAATGGVVRGADLIEQ
MMAR_1974|M.marinum_M GSARLIRPLGAEALAAAVNEVLSSPGYREAAQRAAASIADVADPVQVCHE
MUL_3383|M.ulcerans_Agy99 GSARLIRPLGADALAAAVNEVLSSPGYREAAQRAAASIADVADPVQVCHE
MAV_3631|M.avium_104 GSARLIRPLSADALVAAVNEVLSSPGYRAAAQRAAAGIADVADPVRVCRE
Mb2759c|M.bovis_AF2122/97 GSAVLIRPLTADALVAAVNEVLSSPRFREAARRAAASVAGAADPVRVCHD
Rv2739c|M.tuberculosis_H37Rv GSAVLIRPLTADALVAAVNEVLSSPRFREAARRAAASVAGAADPVRVCHD
MLBr_00985|M.leprae_Br4923 GSAQLIRPLTAAALLAAVNKVLSSPDYREAAQRAAISIAGVADPVQVCHE
MAB_3062c|M.abscessus_ATCC_199 GSAELVRPLSRDSLASAIGRVLGEPRYREAARRAAAGAIAVEDPVRVCQD
TH_3465|M.thermoresistible__bu GIDLGTATPTVRALRAGFDRIRDQDRYRTAARRLAREIRSAAPLDSIAAT
* * . . . :
Mflv_0466|M.gilvum_PYR-GCK RLVARCALPEEQ-----------------------------
Mvan_1905|M.vanbaalenii_PYR-1 LVGGN------------------------------------
MSMEG_2342|M.smegmatis_MC2_155 QVFSSEMRM--------------------------------
MMAR_1974|M.marinum_M ALALAG-----------------------------------
MUL_3383|M.ulcerans_Agy99 ALALAG-----------------------------------
MAV_3631|M.avium_104 ALAG-------------------------------------
Mb2759c|M.bovis_AF2122/97 ALALAG-----------------------------------
Rv2739c|M.tuberculosis_H37Rv ALALAG-----------------------------------
MLBr_00985|M.leprae_Br4923 ALGLAG-----------------------------------
MAB_3062c|M.abscessus_ATCC_199 VLAALR-----------------------------------
TH_3465|M.thermoresistible__bu LERIVAADALNRSARTGSAGAPDPDSTDDRPAPRPARPRVH