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FSLHATRSRASTNAFPRAIFEVSRTTRERTTRTEKFSDCDARQHLCPAQEPVAAREAIPPNLTRYGPLRA GWAIIPAHANPRGLIRMKFALACYGTRGDVEPSVAVGRELQRRGHEVCVAVPPGLVAFAETAGLDAVAYG PELDNFLRDDFLRNFWMQMIRNPVGSLRELWAPITRYWNDTSKVLTTLADGADLLSTGINFEQAAANVAE HYDIPFVSLHHFPMRPNGKLVPALPASVVRSVGALSEWLFWRSTKEVEDAQRRELGLPRTKVPSPRRIAE RGSLEIQAYDAVSVPGLADEWADQNRQRPFTGALTMSLSTEADDDVTSWITSGEPPICFATGSIPVQSPT ATIEMISHACDQLGQRALVCAGGTDLRGVPQFDNVKMVGAVNYAAVFPLCRGIVHHGGSGTTAASLRAGV PTLILWSTADQPYWGNQLKRLKVGTSRRFSGASRKSLVTDLRRILRPEYAVRARELAMRMTPAAESVTIA ADLYENAVRQAAM*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0392 | - | - | 100% (504) | glycosyl transferase |
| M. smegmatis MC2 155 | MSMEG_0385 | - | e-145 | 62.29% (411) | glycosyl transferase |
| M. smegmatis MC2 155 | MSMEG_0389 | - | e-128 | 55.61% (419) | glycosyl transferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1551 | - | 1e-138 | 58.37% (418) | glycosyltransferase |
| M. gilvum PYR-GCK | Mflv_0466 | - | 2e-06 | 25.00% (360) | glycosyl transferase family protein |
| M. tuberculosis H37Rv | Rv1524 | - | 1e-138 | 58.37% (418) | glycosyltransferase |
| M. leprae Br4923 | MLBr_02348 | - | 1e-122 | 54.72% (413) | putative glycosyl transferase |
| M. abscessus ATCC 19977 | MAB_4104 | - | 1e-168 | 67.15% (417) | putative glycosyltransferase GtfB |
| M. marinum M | MMAR_2353 | - | 1e-121 | 52.63% (418) | UDP-glycosyltransferase |
| M. avium 104 | MAV_3258 | - | 1e-162 | 64.75% (417) | glycosyltransferase family protein 28 |
| M. thermoresistible (build 8) | TH_1989 | - | 7e-56 | 69.39% (147) | Glycosyltransferase family protein 28 |
| M. ulcerans Agy99 | MUL_4949 | - | 9e-99 | 47.45% (411) | glycosyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1905 | - | 4e-06 | 23.38% (432) | glycosyl transferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0392|M.smegmatis_MC2_155 MFSLHATRSRASTNAFPRAIFEVSRTTRERTTRTEKFSDCDARQHLCPAQ
MAB_4104|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAV_3258|M.avium_104 --------------------------------------------------
Mb1551|M.bovis_AF2122/97 --------------------------------------------------
Rv1524|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02348|M.leprae_Br4923 --------------------------------------------------
MMAR_2353|M.marinum_M --------------------------------------------------
MUL_4949|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0466|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1905|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0392|M.smegmatis_MC2_155 EPVAAREAIPPNLTRYGPLRAGWAIIPAHANPRGLIRMKFALACYG-TRG
MAB_4104|M.abscessus_ATCC_1997 -------------------------------------MKFALACYG-TRG
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAV_3258|M.avium_104 -------------------------------------MRFALASYG-TRG
Mb1551|M.bovis_AF2122/97 -------------------------------------MKFVVASYG-TRG
Rv1524|M.tuberculosis_H37Rv -------------------------------------MKFVVASYG-TRG
MLBr_02348|M.leprae_Br4923 -------------------------------------MKFTLAASG-SRG
MMAR_2353|M.marinum_M -------------------------------------MKFALAING-TRG
MUL_4949|M.ulcerans_Agy99 -------------------------------------MKAVVASYG-SRG
Mflv_0466|M.gilvum_PYR-GCK -------------------------------------MAVILAYTAPALG
Mvan_1905|M.vanbaalenii_PYR-1 -------------------------------------MATILAYTSPALG
MSMEG_0392|M.smegmatis_MC2_155 DVEPSVAVGRELQRRGHEVCVAVPPGLVAFAETAGLDAVAYGP-ELDNFL
MAB_4104|M.abscessus_ATCC_1997 DVEPSVSVGCELSRRGHDVSIAVPPELIGFAESAGLAAVPYGP-KLHDFL
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAV_3258|M.avium_104 DIEPSAAVGRELLRRGHDVRLAVPPELVGFVESTGLAAVPYGP-NVQEFL
Mb1551|M.bovis_AF2122/97 DIEPCAAVGLELQRRGHDVCLAVPPNLIGFVETAGLSAVAYGSRDSQEQL
Rv1524|M.tuberculosis_H37Rv DIEPCAAVGLELQRRGHDVCLAVPPNLIGFVETAGLSAVAYGSRDSQEQL
MLBr_02348|M.leprae_Br4923 DVEPFAALGLELQRRGHEVRIGVPPDMLRFVESAGLAAVAYGP-DTQEFL
MMAR_2353|M.marinum_M DVEPCAALGRELSRRGHEVRVAVPPNLTGLAAAAGLEAVPYGP-DTDELL
MUL_4949|M.ulcerans_Agy99 DVEPCAAAARELLRRGHEVRVAAPPNLVGFLESAGLTTVAYGP-DSHQQM
Mflv_0466|M.gilvum_PYR-GCK HLFPFCAVLQELARRGHDIHVRTLAAGLQICRDEGFTAAAVDP-RIEAIQ
Mvan_1905|M.vanbaalenii_PYR-1 HLLPMGALLSELSRRGHTVHLRTLSSGLDHARGLGVSVEPIDP-RIEAIE
MSMEG_0392|M.smegmatis_MC2_155 RDD---FLRNFWMQMIRNPVGSLRELWAPITRYWNDTSKVLTTLADGADL
MAB_4104|M.abscessus_ATCC_1997 QDE---FLRTFWTRLMRNPIGALRELWAPIARYWPDTSTTLLSLAEDADL
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAV_3258|M.avium_104 DEE---FLRNMWRDFFRNPIRLVLKVWDPIIKYWAEASATLKSVAEGADL
Mb1551|M.bovis_AF2122/97 DEQ---FLHNAWK--LQNPIKLLREAMAPVTEGWAELSAMLTPVAAGADL
Rv1524|M.tuberculosis_H37Rv DEQ---FLHNAWK--LQNPIKLLREAMAPVTEGWAELSAMLTPVAAGADL
MLBr_02348|M.leprae_Br4923 ARDTYSQWRQWWK--ILPPIKALQQ----LRQAWADMATDLKSLADGADL
MMAR_2353|M.marinum_M NDE--DNLQEFWK--PQTSIKLVREGISDLRQAWSDMAGTLKTLADGADL
MUL_4949|M.ulcerans_Agy99 GPAP--NLVGDLAATAQHPITMVPKLIEHLTRVNAAKSETLTALADGADL
Mflv_0466|M.gilvum_PYR-GCK ADD------TLTG-TVRAAADTVEVLTARAPLEVADLLSAVESVQP--DV
Mvan_1905|M.vanbaalenii_PYR-1 LDD------WKASNPVGALKLSIGAFGRRASYEIADLGKALTTVQP--DG
MSMEG_0392|M.smegmatis_MC2_155 LSTGINFEQAAANVAEHYDIPFVSLH-HFPMRPNGKLVP--ALPASVVRS
MAB_4104|M.abscessus_ATCC_1997 LSTGLNFEQSAGNVAEYFDIPLIMLH-HFPMRPNGQLLP--MLPARLVRS
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAV_3258|M.avium_104 LSTGLNFEQAAANVAEYYDIPLASLH-HFPMRANGQLVP--NMPSPLVRS
Mb1551|M.bovis_AF2122/97 LLTGQIYQEVVANVAEHHGIPLAALH-FYPVRANGEIAFPARLPAPLVRS
Rv1524|M.tuberculosis_H37Rv LLTGQIYQEVVANVAEHHGIPLAALH-FYPVRANGEIAFPARLPAPLVRS
MLBr_02348|M.leprae_Br4923 VMTGVVYQGVVANVAEYYGIPFGVLH-FVPARVNGKIIP--SLPSPLNRA
MMAR_2353|M.marinum_M VLTGMIHQGIALNAAEYYGIPLATMH-FLPSRVNSRVIP--ILSPRLNRS
MUL_4949|M.ulcerans_Agy99 LVVGFNEQAVAANVAEYFGIPLAGLH-FFPAP---------ALPAGMLST
Mflv_0466|M.gilvum_PYR-GCK VIVDANCWGAMS-VAETLGRPWVVLSPFTPYLRSPGAPPFGPGATPWPGP
Mvan_1905|M.vanbaalenii_PYR-1 VLVDVNCWGAHS-AVEATGVPWASFAPYTPALTVAGVPPFGLGLKPMSGP
MSMEG_0392|M.smegmatis_MC2_155 VGALSEWLFWRSTKEVEDAQRRELGLPRTKVPSPRRIAERGSLEIQAYDA
MAB_4104|M.abscessus_ATCC_1997 GGLLSEWLLWRATKDADDAQREVLGLPRATRPSAFRTARRGAVEIQAYDA
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAV_3258|M.avium_104 TMTAIEWLFWRSTKKVDNAQRRQLGLPKATRRSQRRIAERGWLEIQAYDE
Mb1551|M.bovis_AF2122/97 TITAIDWLYWRMTKGVEDAQRRELGLPKASTPAPRRMAVRGSLEIQAYDA
Rv1524|M.tuberculosis_H37Rv TITAIDWLYWRMTKGVEDAQRRELGLPKASTPAPRRMAVRGSLEIQAYDA
MLBr_02348|M.leprae_Br4923 ILATVWRAHWLLAKKPEDAQRRELGLPKATSLSTRRIVKRGALEIQAYDE
MMAR_2353|M.marinum_M VISALWWVHWRVTKNPEEAQRRELGMAKASSSSTSRILKGRSLEIQAYDE
MUL_4949|M.ulcerans_Agy99 ----------LATKAADDAQRQALGLPPASESVPQRVAEQGSLEIQAYDQ
Mflv_0466|M.gilvum_PYR-GCK LGRIRDWGIGLVTTAVFDRPFARQIAPLRRALGLTPVRTAGDLLLRAPAV
Mvan_1905|M.vanbaalenii_PYR-1 VGRLRDSVVRAGVSWPLERPAVAAINTVRSRVGLTPVGSLDQFLRRAPLL
MSMEG_0392|M.smegmatis_MC2_155 VSVPGLADEWADQNRQRPFTGALTMSLSTEADDDVTSWITSGEPPICFAT
MAB_4104|M.abscessus_ATCC_1997 VSVPGLAMEWAKWGDSRPFVGALTMGLTTGADQDVAAWLAAGKPPICFAT
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAV_3258|M.avium_104 VCFPGLAAEWAHWGDRRPFVGALTMELPTESDDDVASWIAAGTPPICFGS
Mb1551|M.bovis_AF2122/97 LCFPGLAAEWG---GRRPFVGALTMESATDADDEVASWIAADTPPIYFGF
Rv1524|M.tuberculosis_H37Rv LCFPGLAAEWG---GRRPFVGALTMESATDADDEVASWIAADTPPIYFGF
MLBr_02348|M.leprae_Br4923 LCFPGLAAEWAEYGDRRPFVGALTLELPTAADNEVLSWIAAGTPPIYFGF
MMAR_2353|M.marinum_M LCFPGLAAEWAEWGDRRPFVGALTLEMPTESDNEVLSWIASGTPPIYFGF
MUL_4949|M.ulcerans_Agy99 IVLPGPPGRWVQADGRHPFIGALTLQSPTDDDDAILAWIAEGAPPIYFGF
Mflv_0466|M.gilvum_PYR-GCK LVATGKPLEYP-HTDWGETVTMIGPAVFEPRAAQRPSWLDHIDDPIVLVT
Mvan_1905|M.vanbaalenii_PYR-1 FLATGTPFQY--AADWGENVHMIGPCAPEKAHGDAPDWLTAIDRPIVLVT
MSMEG_0392|M.smegmatis_MC2_155 GSIPVQSPTATIEMISHACDQLGQRALVCAGGTDLRGVPQFDNVKMVGAV
MAB_4104|M.abscessus_ATCC_1997 GSIPLESPSDTVEMISSACAELGERGLICAGGTDFSEITIPDHVKVVGAV
TH_1989|M.thermoresistible__bu -------------MFASVCSRLGERALICAGGTDIDGVPEYGHVKVVGAV
MAV_3258|M.avium_104 GSIPLESPTATVEMIGAASARLGERALICFGGTDVRGVPRFDHVKVVGPV
Mb1551|M.bovis_AF2122/97 GSMPIGSLADRVAMISAACAELGERALICSGPSDATGIPQFDHVKVVRVV
Rv1524|M.tuberculosis_H37Rv GSMPIGSLADRVAMISAACAELGERALICSGPSDATGIPQFDHVKVVRVV
MLBr_02348|M.leprae_Br4923 GSMPIVSPTDTVAMIAAACADLGERALISVKPKDLTQVPKFDHVKIVTSV
MMAR_2353|M.marinum_M GSMPVESPAATIAMISAACAELGERALICTGSNDLGGLQAPENVKLVSGV
MUL_4949|M.ulcerans_Agy99 GSTPLTSPAEQFAMISAACAQLGERALICAGPNDFGQMPHSHQVMVAPAV
Mflv_0466|M.gilvum_PYR-GCK TSSVGQSDAALVETAVEALRDE-PVHLVVTAPTGDVDVMTRPGVTQVRFA
Mvan_1905|M.vanbaalenii_PYR-1 TSSERQGDAGLVSAAVDALTDE-PVHVVATLPAGVDQVPGSAHATILRFV
. :: . : . .
MSMEG_0392|M.smegmatis_MC2_155 NYAAVFPLCRGIVHHGGSGTTAASLRAGVPTLILWSTADQPYWGNQLKRL
MAB_4104|M.abscessus_ATCC_1997 NYAAVFAASRAVVHHGGSGTTAASLRAGVPTLILWSSADQPYWGNQLSRL
TH_1989|M.thermoresistible__bu NYARVFPACRAIVHHGGSGTTAAVLRAGVPSLVTWSSADQPYWGNQVKRL
MAV_3258|M.avium_104 NYASVFPACRAVVHHGGSGTTAASLRAGIPTLALWSSADQPYWAAQIKRL
Mb1551|M.bovis_AF2122/97 SHAAVFPTCRAVVHHGGAGTTAAGLRAGIPTLILWVTSDQPIWAAQIKQL
Rv1524|M.tuberculosis_H37Rv SHAAVFPTCRAVVHHGGAGTTAAGLRAGIPTLILWVTSDQPIWAAQIKQL
MLBr_02348|M.leprae_Br4923 SHAAVFPACRAVVHHGGAGTTAASLRAGVPTLILWIFIEQPVWAAQIKRL
MMAR_2353|M.marinum_M SHAAVFPACRAVVHHGGAGTTAAGMRAGIPTLILWIWIEQPIWLAQIKRL
MUL_4949|M.ulcerans_Agy99 NHAAVFPACRAIVHHGGAGTTAAGLRAGIPMLIRWLWLDQPIWAAGIEEL
Mflv_0466|M.gilvum_PYR-GCK PHSMLLEHAVCVITHGGMGVTQKALARGVPVCVVPFGRDQFEVARRVELA
Mvan_1905|M.vanbaalenii_PYR-1 DHDLVLGRAVCAVTHGGMGATQRALARGVPVCVVPYGRDQFEVARRAEVA
: :: . : *** *.* : *:* :* .
MSMEG_0392|M.smegmatis_MC2_155 KVGTSRRFSGASRKSLVTDLRRILRPEYAVRARELAMRMTPAAESVTIAA
MAB_4104|M.abscessus_ATCC_1997 KVGAARRFSATDRNTLAADLRRVLLPEYAVAARAVSAQMTSPTDSVTKAA
TH_1989|M.thermoresistible__bu KVGTSRRFSHTTPDTLVADLRRILTPDYAVRARAVAARMTDPADSVVRAA
MAV_3258|M.avium_104 KVGTARRFSATTSETLAADLRTILAPDYATRARDLAARMTKPAESIETTA
Mb1551|M.bovis_AF2122/97 KVGRGRRFSSATKESLIADLRTILAPDYVTRAREIASRMTKPAASVTATA
Rv1524|M.tuberculosis_H37Rv KVGRGRRFSSATKESLIADLRTILAPDYVTRAREIASRMTKPAASVTATA
MLBr_02348|M.leprae_Br4923 KVGAGRRFSATTQRSLAADLRTILAPQYATRAREVANRMSKPDESVNAAA
MMAR_2353|M.marinum_M KIGSGRRLASTTKETLVSDLRCILGPDYVARARTIANEMSKPGESATRAA
MUL_4949|M.ulcerans_Agy99 GVGVGQPFSAATSESLAAGLGSILAAQYIARARTVADQMTPPAHSIAMAA
Mflv_0466|M.gilvum_PYR-GCK GCGTRLPAGKLSVGRLRTAVKTAAT--MTGGAARVAAGFAATG-GVARGA
Mvan_1905|M.vanbaalenii_PYR-1 RCGTRLPAKRLSAPRLRNKIREAMG--LTSGARAVADGFAATG-GVARGA
* * : * :: :: . . *
MSMEG_0392|M.smegmatis_MC2_155 DLYENAVRQAAM-------
MAB_4104|M.abscessus_ATCC_1997 DLFESTAGRKAV-------
TH_1989|M.thermoresistible__bu DLFETAVECAPGVAHRE--
MAV_3258|M.avium_104 DLLEEAARRKTLG------
Mb1551|M.bovis_AF2122/97 DLLEDAARRAR--------
Rv1524|M.tuberculosis_H37Rv DLLEDAARRAR--------
MLBr_02348|M.leprae_Br4923 DLLEDKASRNKSRTRYQDC
MMAR_2353|M.marinum_M DLLENEVSVS---------
MUL_4949|M.ulcerans_Agy99 DLLEHTAHVDRRS------
Mflv_0466|M.gilvum_PYR-GCK DVVESRLVARCALPEEQ--
Mvan_1905|M.vanbaalenii_PYR-1 DLFEHLVGGN---------
*: *