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MKFVVASYGTRGDIEPCAAVGLELQRRGHDVCLAVPPNLIGFVETAGLSAVAYGSRDSQEQLDEQFLHNA WKLQNPIKLLREAMAPVTEGWAELSAMLTPVAAGADLLLTGQIYQEVVANVAEHHGIPLAALHFYPVRAN GEIAFPARLPAPLVRSTITAIDWLYWRMTKGVEDAQRRELGLPKASTPAPRRMAVRGSLEIQAYDALCFP GLAAEWGGRRPFVGALTMESATDADDEVASWIAADTPPIYFGFGSMPIGSLADRVAMISAACAELGERAL ICSGPSDATGIPQFDHVKVVRVVSHAAVFPTCRAVVHHGGAGTTAAGLRAGIPTLILWVTSDQPIWAAQI KQLKVGRGRRFSSATKESLIADLRTILAPDYVTRAREIASRMTKPAASVTATADLLEDAARRAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1551 | - | - | 100% (414) | glycosyltransferase |
| M. bovis AF2122 / 97 | Mb1553c | - | e-134 | 58.55% (415) | glycosyltransferase |
| M. bovis AF2122 / 97 | Mb2759c | - | 2e-05 | 26.17% (298) | alanine rich transferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0466 | - | 8e-07 | 25.37% (402) | glycosyl transferase family protein |
| M. tuberculosis H37Rv | Rv1524 | - | 0.0 | 100.00% (414) | glycosyltransferase |
| M. leprae Br4923 | MLBr_02348 | - | 1e-144 | 62.68% (418) | putative glycosyl transferase |
| M. abscessus ATCC 19977 | MAB_4112c | - | 1e-136 | 59.09% (418) | putative glycosyltransferase GtfA |
| M. marinum M | MMAR_2353 | - | 1e-138 | 60.10% (411) | UDP-glycosyltransferase |
| M. avium 104 | MAV_3258 | - | 1e-153 | 65.23% (417) | glycosyltransferase family protein 28 |
| M. smegmatis MC2 155 | MSMEG_0392 | - | 1e-138 | 58.37% (418) | glycosyl transferase |
| M. thermoresistible (build 8) | TH_1989 | - | 3e-48 | 58.50% (147) | Glycosyltransferase family protein 28 |
| M. ulcerans Agy99 | MUL_4949 | - | 1e-115 | 54.46% (415) | glycosyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1905 | - | 3e-08 | 24.72% (356) | glycosyl transferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1551|M.bovis_AF2122/97 --------------------------------------------------
Rv1524|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_0392|M.smegmatis_MC2_155 MFSLHATRSRASTNAFPRAIFEVSRTTRERTTRTEKFSDCDARQHLCPAQ
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAV_3258|M.avium_104 --------------------------------------------------
MAB_4112c|M.abscessus_ATCC_199 ------------------------------------------------MA
MLBr_02348|M.leprae_Br4923 --------------------------------------------------
MMAR_2353|M.marinum_M --------------------------------------------------
MUL_4949|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0466|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1905|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1551|M.bovis_AF2122/97 -------------------------------------MKFVVASYG-TRG
Rv1524|M.tuberculosis_H37Rv -------------------------------------MKFVVASYG-TRG
MSMEG_0392|M.smegmatis_MC2_155 EPVAAREAIPPNLTRYGPLRAGWAIIPAHANPRGLIRMKFALACYG-TRG
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAV_3258|M.avium_104 -------------------------------------MRFALASYG-TRG
MAB_4112c|M.abscessus_ATCC_199 ENIDVHSVAHSDIG------------------EVYTVMKFAMASYG-TRG
MLBr_02348|M.leprae_Br4923 -------------------------------------MKFTLAASG-SRG
MMAR_2353|M.marinum_M -------------------------------------MKFALAING-TRG
MUL_4949|M.ulcerans_Agy99 -------------------------------------MKAVVASYG-SRG
Mflv_0466|M.gilvum_PYR-GCK -------------------------------------MAVILAYTAPALG
Mvan_1905|M.vanbaalenii_PYR-1 -------------------------------------MATILAYTSPALG
Mb1551|M.bovis_AF2122/97 DIEPCAAVGLELQRRGHDVCLAVPPNLIGFVETAGLSAVAYG-----SRD
Rv1524|M.tuberculosis_H37Rv DIEPCAAVGLELQRRGHDVCLAVPPNLIGFVETAGLSAVAYG-----SRD
MSMEG_0392|M.smegmatis_MC2_155 DVEPSVAVGRELQRRGHEVCVAVPPGLVAFAETAGLDAVAY----GPELD
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAV_3258|M.avium_104 DIEPSAAVGRELLRRGHDVRLAVPPELVGFVESTGLAAVPY----GPNVQ
MAB_4112c|M.abscessus_ATCC_199 DIEPAVAVGRELQRRGHEVRMAVPPDLIGFAGSVGLSAVPYGIHVGPQLD
MLBr_02348|M.leprae_Br4923 DVEPFAALGLELQRRGHEVRIGVPPDMLRFVESAGLAAVAYG---PDTQE
MMAR_2353|M.marinum_M DVEPCAALGRELSRRGHEVRVAVPPNLTGLAAAAGLEAVPYG---PDTDE
MUL_4949|M.ulcerans_Agy99 DVEPCAAAARELLRRGHEVRVAAPPNLVGFLESAGLTTVAYG----PDSH
Mflv_0466|M.gilvum_PYR-GCK HLFPFCAVLQELARRGHDIHVRTLAAGLQICRDEGFTAAAVD--------
Mvan_1905|M.vanbaalenii_PYR-1 HLLPMGALLSELSRRGHTVHLRTLSSGLDHARGLGVSVEPID--------
Mb1551|M.bovis_AF2122/97 SQEQLDEQFLHNAWK--LQNPIKLLREAMAPVTEGWAELSAMLTPVAAGA
Rv1524|M.tuberculosis_H37Rv SQEQLDEQFLHNAWK--LQNPIKLLREAMAPVTEGWAELSAMLTPVAAGA
MSMEG_0392|M.smegmatis_MC2_155 NF--LRDDFLRNFWMQMIRNPVGSLRELWAPITRYWNDTSKVLTTLADGA
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAV_3258|M.avium_104 EF--LDEEFLRNMWRDFFRNPIRLVLKVWDPIIKYWAEASATLKSVAEGA
MAB_4112c|M.abscessus_ATCC_199 EYRDLWTSWTRHFWR--LQDLVALCRQALKLVTEQWSEMSETLVSVAEGA
MLBr_02348|M.leprae_Br4923 FLARDTYSQWRQWWK--ILPPIKALQQ----LRQAWADMATDLKSLADGA
MMAR_2353|M.marinum_M LLNDE--DNLQEFWK--PQTSIKLVREGISDLRQAWSDMAGTLKTLADGA
MUL_4949|M.ulcerans_Agy99 QQMGPAPNLVGDLAAT-AQHPITMVPKLIEHLTRVNAAKSETLTALADGA
Mflv_0466|M.gilvum_PYR-GCK -PRIEAIQADDTLTG-TVRAAADTVEVLTARAPLEVADLLSAVESVQP--
Mvan_1905|M.vanbaalenii_PYR-1 -PRIEAIELDDWKASNPVGALKLSIGAFGRRASYEIADLGKALTTVQP--
Mb1551|M.bovis_AF2122/97 DLLLTGQIYQEVVANVAEHHGIPLAALH-FYPVRANGEIAFPARLPAPLV
Rv1524|M.tuberculosis_H37Rv DLLLTGQIYQEVVANVAEHHGIPLAALH-FYPVRANGEIAFPARLPAPLV
MSMEG_0392|M.smegmatis_MC2_155 DLLSTGINFEQAAANVAEHYDIPFVSLH-HFPMRPNGKLVP--ALPASVV
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAV_3258|M.avium_104 DLLSTGLNFEQAAANVAEYYDIPLASLH-HFPMRANGQLVP--NMPSPLV
MAB_4112c|M.abscessus_ATCC_199 DLLSTSVGYEEPAANVAEFYGIPLVALH-TMPWRPNGQLFP--VLPPMLT
MLBr_02348|M.leprae_Br4923 DLVMTGVVYQGVVANVAEYYGIPFGVLH-FVPARVNGKIIP--SLPSPLN
MMAR_2353|M.marinum_M DLVLTGMIHQGIALNAAEYYGIPLATMH-FLPSRVNSRVIP--ILSPRLN
MUL_4949|M.ulcerans_Agy99 DLLVVGFNEQAVAANVAEYFGIPLAGLH-FFPAP---------ALPAGML
Mflv_0466|M.gilvum_PYR-GCK DVVIVDANCWGAMS-VAETLGRPWVVLSPFTPYLRSPGAPPFGPGATPWP
Mvan_1905|M.vanbaalenii_PYR-1 DGVLVDVNCWGAHS-AVEATGVPWASFAPYTPALTVAGVPPFGLGLKPMS
Mb1551|M.bovis_AF2122/97 RSTITAIDWLYWRMTKGVEDAQRRELGLPKASTPAPRRMAVRGSLEIQAY
Rv1524|M.tuberculosis_H37Rv RSTITAIDWLYWRMTKGVEDAQRRELGLPKASTPAPRRMAVRGSLEIQAY
MSMEG_0392|M.smegmatis_MC2_155 RSVGALSEWLFWRSTKEVEDAQRRELGLPRTKVPSPRRIAERGSLEIQAY
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAV_3258|M.avium_104 RSTMTAIEWLFWRSTKKVDNAQRRQLGLPKATRRSQRRIAERGWLEIQAY
MAB_4112c|M.abscessus_ATCC_199 RTGMTAYDWLTWRVTKGAEDAQRRHLGLPQATSPSPQRIGQRNSLEIQAY
MLBr_02348|M.leprae_Br4923 RAILATVWRAHWLLAKKPEDAQRRELGLPKATSLSTRRIVKRGALEIQAY
MMAR_2353|M.marinum_M RSVISALWWVHWRVTKNPEEAQRRELGMAKASSSSTSRILKGRSLEIQAY
MUL_4949|M.ulcerans_Agy99 ST----------LATKAADDAQRQALGLPPASESVPQRVAEQGSLEIQAY
Mflv_0466|M.gilvum_PYR-GCK GPLGRIRDWGIGLVTTAVFDRPFARQIAPLRRALGLTPVRTAGDLLLRAP
Mvan_1905|M.vanbaalenii_PYR-1 GPVGRLRDSVVRAGVSWPLERPAVAAINTVRSRVGLTPVGSLDQFLRRAP
Mb1551|M.bovis_AF2122/97 DALCFPGLAAEWG---GRRPFVGALTMESATDADDEVASWIAADTPPIYF
Rv1524|M.tuberculosis_H37Rv DALCFPGLAAEWG---GRRPFVGALTMESATDADDEVASWIAADTPPIYF
MSMEG_0392|M.smegmatis_MC2_155 DAVSVPGLADEWADQNRQRPFTGALTMSLSTEADDDVTSWITSGEPPICF
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAV_3258|M.avium_104 DEVCFPGLAAEWAHWGDRRPFVGALTMELPTESDDDVASWIAAGTPPICF
MAB_4112c|M.abscessus_ATCC_199 DAVCFRGLAEEWAKYGGRRPFVGALTMELTTSADDEVMSWIASGPPPICF
MLBr_02348|M.leprae_Br4923 DELCFPGLAAEWAEYGDRRPFVGALTLELPTAADNEVLSWIAAGTPPIYF
MMAR_2353|M.marinum_M DELCFPGLAAEWAEWGDRRPFVGALTLEMPTESDNEVLSWIASGTPPIYF
MUL_4949|M.ulcerans_Agy99 DQIVLPGPPGRWVQADGRHPFIGALTLQSPTDDDDAILAWIAEGAPPIYF
Mflv_0466|M.gilvum_PYR-GCK AVLVATGKPLEYP-HTDWGETVTMIGPAVFEPRAAQRPSWLDHIDDPIVL
Mvan_1905|M.vanbaalenii_PYR-1 LLFLATGTPFQY--AADWGENVHMIGPCAPEKAHGDAPDWLTAIDRPIVL
Mb1551|M.bovis_AF2122/97 GFGSMPIGSLADRVAMISAACAELGERALICSGPSDATGIPQFDHVKVVR
Rv1524|M.tuberculosis_H37Rv GFGSMPIGSLADRVAMISAACAELGERALICSGPSDATGIPQFDHVKVVR
MSMEG_0392|M.smegmatis_MC2_155 ATGSIPVQSPTATIEMISHACDQLGQRALVCAGGTDLRGVPQFDNVKMVG
TH_1989|M.thermoresistible__bu ---------------MFASVCSRLGERALICAGGTDIDGVPEYGHVKVVG
MAV_3258|M.avium_104 GSGSIPLESPTATVEMIGAASARLGERALICFGGTDVRGVPRFDHVKVVG
MAB_4112c|M.abscessus_ATCC_199 ASGSIPVESPAETVEMIGSACAELGERALVCAGATDFSGVQTSPHVKLVG
MLBr_02348|M.leprae_Br4923 GFGSMPIVSPTDTVAMIAAACADLGERALISVKPKDLTQVPKFDHVKIVT
MMAR_2353|M.marinum_M GFGSMPVESPAATIAMISAACAELGERALICTGSNDLGGLQAPENVKLVS
MUL_4949|M.ulcerans_Agy99 GFGSTPLTSPAEQFAMISAACAQLGERALICAGPNDFGQMPHSHQVMVAP
Mflv_0466|M.gilvum_PYR-GCK VTTSSVGQSDAALVETAVEALRDE-PVHLVVTAPTGDVDVMTRPGVTQVR
Mvan_1905|M.vanbaalenii_PYR-1 VTTSSERQGDAGLVSAAVDALTDE-PVHVVATLPAGVDQVPGSAHATILR
. :: . : .
Mb1551|M.bovis_AF2122/97 VVSHAAVFPTCRAVVHHGGAGTTAAGLRAGIPTLILWVTSDQPIWAAQIK
Rv1524|M.tuberculosis_H37Rv VVSHAAVFPTCRAVVHHGGAGTTAAGLRAGIPTLILWVTSDQPIWAAQIK
MSMEG_0392|M.smegmatis_MC2_155 AVNYAAVFPLCRGIVHHGGSGTTAASLRAGVPTLILWSTADQPYWGNQLK
TH_1989|M.thermoresistible__bu AVNYARVFPACRAIVHHGGSGTTAAVLRAGVPSLVTWSSADQPYWGNQVK
MAV_3258|M.avium_104 PVNYASVFPACRAVVHHGGSGTTAASLRAGIPTLALWSSADQPYWAAQIK
MAB_4112c|M.abscessus_ATCC_199 VVNYAAVFPVSRAIVHHGGSGTTAASLRAGVPTLILWTVGDQPFWGNQLR
MLBr_02348|M.leprae_Br4923 SVSHAAVFPACRAVVHHGGAGTTAASLRAGVPTLILWIFIEQPVWAAQIK
MMAR_2353|M.marinum_M GVSHAAVFPACRAVVHHGGAGTTAAGMRAGIPTLILWIWIEQPIWLAQIK
MUL_4949|M.ulcerans_Agy99 AVNHAAVFPACRAIVHHGGAGTTAAGLRAGIPMLIRWLWLDQPIWAAGIE
Mflv_0466|M.gilvum_PYR-GCK FAPHSMLLEHAVCVITHGGMGVTQKALARGVPVCVVPFGRDQFEVARRVE
Mvan_1905|M.vanbaalenii_PYR-1 FVDHDLVLGRAVCAVTHGGMGATQRALARGVPVCVVPYGRDQFEVARRAE
. : :: . : *** *.* : *:* :* .
Mb1551|M.bovis_AF2122/97 QLKVGRGRRFSSATKESLIADLRTILAPDYVTRAREIASRMTKPAASVTA
Rv1524|M.tuberculosis_H37Rv QLKVGRGRRFSSATKESLIADLRTILAPDYVTRAREIASRMTKPAASVTA
MSMEG_0392|M.smegmatis_MC2_155 RLKVGTSRRFSGASRKSLVTDLRRILRPEYAVRARELAMRMTPAAESVTI
TH_1989|M.thermoresistible__bu RLKVGTSRRFSHTTPDTLVADLRRILTPDYAVRARAVAARMTDPADSVVR
MAV_3258|M.avium_104 RLKVGTARRFSATTSETLAADLRTILAPDYATRARDLAARMTKPAESIET
MAB_4112c|M.abscessus_ATCC_199 RMGVGASRRFSTTTRDSLVSDLRTILTPECAARARAIAPHMSKPHDSVSK
MLBr_02348|M.leprae_Br4923 RLKVGAGRRFSATTQRSLAADLRTILAPQYATRAREVANRMSKPDESVNA
MMAR_2353|M.marinum_M RLKIGSGRRLASTTKETLVSDLRCILGPDYVARARTIANEMSKPGESATR
MUL_4949|M.ulcerans_Agy99 ELGVGVGQPFSAATSESLAAGLGSILAAQYIARARTVADQMTPPAHSIAM
Mflv_0466|M.gilvum_PYR-GCK LAGCGTRLPAGKLSVGRLRTAVKTAAT--MTGGAARVAAGFAATG-GVAR
Mvan_1905|M.vanbaalenii_PYR-1 VARCGTRLPAKRLSAPRLRNKIREAMG--LTSGARAVADGFAATG-GVAR
* : * : * :* :: . .
Mb1551|M.bovis_AF2122/97 TADLLEDAARRAR--------
Rv1524|M.tuberculosis_H37Rv TADLLEDAARRAR--------
MSMEG_0392|M.smegmatis_MC2_155 AADLYENAVRQAAM-------
TH_1989|M.thermoresistible__bu AADLFETAVECAPGVAHRE--
MAV_3258|M.avium_104 TADLLEEAARRKTLG------
MAB_4112c|M.abscessus_ATCC_199 AADLLEAKASHP---------
MLBr_02348|M.leprae_Br4923 AADLLEDKASRNKSRTRYQDC
MMAR_2353|M.marinum_M AADLLENEVSVS---------
MUL_4949|M.ulcerans_Agy99 AADLLEHTAHVDRRS------
Mflv_0466|M.gilvum_PYR-GCK GADVVESRLVARCALPEEQ--
Mvan_1905|M.vanbaalenii_PYR-1 GADLFEHLVGGN---------
**: *