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MATILAYTSPALGHLLPMGALLSELSRRGHTVHLRTLSSGLDHARGLGVSVEPIDPRIEAIELDDWKASN PVGALKLSIGAFGRRASYEIADLGKALTTVQPDGVLVDVNCWGAHSAVEATGVPWASFAPYTPALTVAGV PPFGLGLKPMSGPVGRLRDSVVRAGVSWPLERPAVAAINTVRSRVGLTPVGSLDQFLRRAPLLFLATGTP FQYAADWGENVHMIGPCAPEKAHGDAPDWLTAIDRPIVLVTTSSERQGDAGLVSAAVDALTDEPVHVVAT LPAGVDQVPGSAHATILRFVDHDLVLGRAVCAVTHGGMGATQRALARGVPVCVVPYGRDQFEVARRAEVA RCGTRLPAKRLSAPRLRNKIREAMGLTSGARAVADGFAATGGVARGADLFEHLVGGN
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_1905 | - | - | 100% (407) | glycosyl transferase family protein |
M. vanbaalenii PYR-1 | Mvan_4034 | - | 3e-31 | 29.44% (428) | glycosyl transferase family protein |
M. vanbaalenii PYR-1 | Mvan_4035 | - | 5e-25 | 28.74% (428) | glycosyl transferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2759c | - | 3e-25 | 29.38% (405) | alanine rich transferase |
M. gilvum PYR-GCK | Mflv_0466 | - | 1e-114 | 53.48% (402) | glycosyl transferase family protein |
M. tuberculosis H37Rv | Rv2739c | - | 3e-25 | 29.38% (405) | alanine rich transferase |
M. leprae Br4923 | MLBr_00985 | - | 3e-23 | 26.32% (418) | putative glycosyltransferase |
M. abscessus ATCC 19977 | MAB_3062c | - | 1e-23 | 29.37% (395) | hypothetical protein MAB_3062c |
M. marinum M | MMAR_1974 | - | 2e-24 | 29.02% (410) | glycosyl transferase |
M. avium 104 | MAV_3631 | - | 3e-28 | 31.13% (408) | hypothetical protein MAV_3631 |
M. smegmatis MC2 155 | MSMEG_2342 | - | 1e-117 | 52.46% (406) | putative glycosyltransferase |
M. thermoresistible (build 8) | TH_4587 | - | 4e-18 | 25.53% (423) | PUTATIVE putative oleandomycin glycosyltransferase |
M. ulcerans Agy99 | MUL_3383 | - | 9e-24 | 28.78% (410) | glycosyl transferase |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_1905|M.vanbaalenii_PYR-1 ---MATILAYTSPALGHLLPMGALLSELSRRGHTVHLRTLSSGLDHARGL Mflv_0466|M.gilvum_PYR-GCK ---MAVILAYTAPALGHLFPFCAVLQELARRGHDIHVRTLAAGLQICRDE MSMEG_2342|M.smegmatis_MC2_155 ---MATILAYTSPALGHVYPLAALLTELACRGHEIHLRTMAREVEAMRAA MMAR_1974|M.marinum_M ----MRVAVVAGPDPGHSFPAIALCRRFLAAGDIPTLLTGVEWLDTARAA MUL_3383|M.ulcerans_Agy99 ----MRVAVVAGPDPGHSFPAIALCRRFLAAGDIPTLLTGVEWLDTARAA MAV_3631|M.avium_104 ----MRVAVVAGPDPGHSFPAIALCRRFADAGDTPTLFTGAEWLDTARGA Mb2759c|M.bovis_AF2122/97 ----MRVAVVAGPDPGHSFPAIALCQRFRAAADTPTLFTGVEWLEAARAA Rv2739c|M.tuberculosis_H37Rv ----MRVAVVAGPDPGHSFPAIALCQRFRAAADTPTLFTGVEWLEAARAA MLBr_00985|M.leprae_Br4923 MVHYMRVAVVAGPDPGHSFPAIALCQRFAEAGDTPTLFTGVECVDIARAA MAB_3062c|M.abscessus_ATCC_199 ----MRVAVVAGPDPGHAFPALALCLKFAAAGDDPVLLTGTRWLDQARAA TH_4587|M.thermoresistible__bu ---VAHIVFAVPVGVGHVNPTLGVAAELIARGHRVSYAATERHAARIADV : . ** * .: .: .. : Mvan_1905|M.vanbaalenii_PYR-1 GVSVEPIDPRIEAIELDDWKASNPVGALKLSIGAFGRRASYEIADLGKAL Mflv_0466|M.gilvum_PYR-GCK GFTAAAVDPRIEAIQADDTLTG-TVRAAADTVEVLTARAPLEVADLLSAV MSMEG_2342|M.smegmatis_MC2_155 GFRADAVAPEIEAIRGDDRSTSDALEVLAMSLDVLCSRAASEVDDIRDAI MMAR_1974|M.marinum_M GVDAIELAGLVA--TDEDLDAGARIHRRAAQMALLN----------APAL MUL_3383|M.ulcerans_Agy99 GVDAIELAGLVA--TDEDLDAGARIHRRAAQMALLN----------APAL MAV_3631|M.avium_104 GVDAVELDGLAA--TDEDVDAGARIHRRAARMAVLN----------VPAL Mb2759c|M.bovis_AF2122/97 GIDAVELDGLAA--TDRDLDAGARIHRRAAQMAVLN----------VPRL Rv2739c|M.tuberculosis_H37Rv GIDAVELDGLAA--TDRDLDAGARIHRRAAQMAVLN----------VPRL MLBr_00985|M.leprae_Br4923 GVETALLDGLVA--VDDDVDAGARIHRRAAQMAVLN----------VPVL MAB_3062c|M.abscessus_ATCC_199 GVESVELLGLQPRVDDDDADSGAKIHQRAAHMALAN----------LDQL TH_4587|M.thermoresistible__bu GARLVPYATTLSGPEPPPQFTARDFHRATEAALRET-------------- * :. . Mvan_1905|M.vanbaalenii_PYR-1 TTVQPDGVLVDVNCWGAHSAVEATGVPWASFAPYTPALTVAGVPPFGLGL Mflv_0466|M.gilvum_PYR-GCK ESVQPDVVIVDANCWGAMSVAETLGRPWVVLSPFTPYLRSPGAPPFGPGA MSMEG_2342|M.smegmatis_MC2_155 ARSRPDLVIVDANCWGAMAAAEAEGLPWAVFSPFTPYLRSRGVPPFGPGL MMAR_1974|M.marinum_M SDLAPDLVVSDVITACGGMAAERLGIPWIELNPHPLYRPSKGLPPIGSGL MUL_3383|M.ulcerans_Agy99 SDLAPDLVVSDVITACGGMAAERLGIPWIELNPHPLYRPSKGLPPIGSGL MAV_3631|M.avium_104 RDLAPDLVVSDVITAGGGMAAELLGIPWIELSPHPLYLPSKGLPPIGSGL Mb2759c|M.bovis_AF2122/97 RALEPELVVSDVITACGGMAAELLGIPWVELNPHPLYLPSKGLPPIGSGL Rv2739c|M.tuberculosis_H37Rv RALEPELVVSDVITACGGMAAELLGIPWVELNPHPLYLPSKGLPPIGSGL MLBr_00985|M.leprae_Br4923 RDLAPDLIVSDVITAAGGMAAELLGIPWIELNPHPLYLPSKGLPPIGSGL MAB_3062c|M.abscessus_ATCC_199 RALAPDLIVSDVITACGGMAGELLGVPWVELNPHPLYLPSKGLPPLGSGL TH_4587|M.thermoresistible__bu GHVLPQVLDGFAGDRPDLVLHDATMAWWGRLAAAAWEVPVVAGWPNLVGN *: : . : * : . . . * * Mvan_1905|M.vanbaalenii_PYR-1 KPMSGPVGRLRDSVVRAGVSWPLERPAVAAINTVRSRVGLTPVGSLDQFL Mflv_0466|M.gilvum_PYR-GCK TPWPGPLGRIRDWGIGLVTTAVFDRPFARQIAPLRRALGLTPVRTAGDLL MSMEG_2342|M.smegmatis_MC2_155 RPWPGLPGRARDALMRRVTGRMFDDPVLRRMNPLRAEAGVPEVDSVDAMM MMAR_1974|M.marinum_M APGTGIRGRLRDTTMRALTARSWR-AGLRQRAAVRAEIGLAEHD------ MUL_3383|M.ulcerans_Agy99 APGTGIRGRLRDTTMRALTARSWR-AGLRQRAAVRAEIGLAEHD------ MAV_3631|M.avium_104 ATGTGLRGRLRDATMRALTARSWR-AGLRQRAAARAEIGLPARD------ Mb2759c|M.bovis_AF2122/97 AAGTGIRGRLRDATMRALTGRSWR-AGLRQRAAVRVEIGLPARD------ Rv2739c|M.tuberculosis_H37Rv AAGTGIRGRLRDATMRALTGRSWR-AGLRQRAAVRVEIGLPARD------ MLBr_00985|M.leprae_Br4923 ASGVGIHGRMRDATMRALTARSWR-AGLRERAAVRVQIGLPACD------ MAB_3062c|M.abscessus_ATCC_199 APGVGLRGRLRDGLMRRLTQKSID-QGLRQRSQARVEIGLPARD------ TH_4587|M.thermoresistible__bu RHWSMNRYIKVNPLHPRLLWNLWR---AHRLARRHGLTGLSLVR-----A : : *:. Mvan_1905|M.vanbaalenii_PYR-1 RRAPLLFLATGTPFQY-AADWGENVHMIGPCAPE-KAHGDAPDWLTAIDR Mflv_0466|M.gilvum_PYR-GCK LRAPAVLVATGKPLEYPHTDWGETVTMIGPAVFE-PRAAQRPSWLDHIDD MSMEG_2342|M.smegmatis_MC2_155 RRAPLTLGVGGRPFEYPHPDWGDSVHQLGACVFE-PGPVAEPPWLAEIDR MMAR_1974|M.marinum_M PGPLRRLIATLPALEVPRPDWPAEAIVVGPLHFE-PTDQLLK--VPAGSG MUL_3383|M.ulcerans_Agy99 PGPLRRLIATLPALEVPRPDWPAEAIVVGPLHFE-PTDQLLK--VPAGSG MAV_3631|M.avium_104 PGPLRRLIATLPALEVPRPDWPDEAVLVGPLHFE-PTDRVLD--IPAGSG Mb2759c|M.bovis_AF2122/97 PGPLRRLIATLPALEVPRPDWPAEAVVVGPLHFE-PTDRVLA--IPAGTG Rv2739c|M.tuberculosis_H37Rv PGPLRRLIATLPALEVPRPDWPAEAVVVGPLHFE-PTDRVLA--IPAGTG MLBr_00985|M.leprae_Br4923 SGPLRRLIATLPALEVSRPDWPAEAVVVGPLHFE-PTDRVLQ--IPSGSG MAB_3062c|M.abscessus_ATCC_199 PGPMRRLIATLPALEVPRPDWPAEAVVVGPLHWE-PTDVVLQ--PPSGSG TH_4587|M.thermoresistible__bu TAADAQLVYLPREFQYAGDTFGAHYAFVGPCLVDRPSDGEWRPPPGRDGR . : :: : :*. : Mvan_1905|M.vanbaalenii_PYR-1 PIVLVTTSSERQGDAGLVSAAVDALTD-----EPVHVVATLPAGVDQ--- Mflv_0466|M.gilvum_PYR-GCK PIVLVTTSSVGQSDAALVETAVEALRD-----EPVHLVVTAPTGDVD--- MSMEG_2342|M.smegmatis_MC2_155 PVVLVNTSSIAQADTILAHTALAAFAD-----EPVHVVATFPAGVPDG-- MMAR_1974|M.marinum_M PVLVIAPSTALSGTAGLAEVALESLIPGDTLPSGSRLVVSRLGGDDL--- MUL_3383|M.ulcerans_Agy99 PVLVIAPSTALSGTAGLAEVALESLIPGGTLSSGSRLVVSRLGGDDL--- MAV_3631|M.avium_104 PVVVVAPSTAQTGARGLAEVALSCLTPGETLPAGARLVVSRLAGPEL--- Mb2759c|M.bovis_AF2122/97 PVVVVAPSTALTGTAGLTEVALQSLTPGETVPSGSRLVVSRLSGADL--- Rv2739c|M.tuberculosis_H37Rv PVVVVAPSTALTGTAGLTEVALQSLTPGETVPSGSRLVVSRLSGADL--- MLBr_00985|M.leprae_Br4923 PVIVVAPSTALTGISGMAQTALDALVPGDTLPSGSRVVVSRLNGPDL--- MAB_3062c|M.abscessus_ATCC_199 PVVVIAPSTAFTGAEGMTELAVQALES-----AGARVVISALEPPSS--- TH_4587|M.thermoresistible__bu RVVLIALGTAYHDRADFFRTCLAAFAD-----SGWHVVLAVGDRVDPAGL :::: .: : .: .: ::* : Mvan_1905|M.vanbaalenii_PYR-1 VPGSAHATILRFVDHDLVLGRAVCAVTHGGMGATQRALARGVPVCVVPYG Mflv_0466|M.gilvum_PYR-GCK VMTRPGVTQVRFAPHSMLLEHAVCVITHGGMGVTQKALARGVPVCVVPFG MSMEG_2342|M.smegmatis_MC2_155 LPRPANATIGEYIPHGVVLDRTVCVVTHGGMGTTLKALDRGIPVCVVPFA MMAR_1974|M.marinum_M --VTPSWAAVGLGSQAELLTHADVVICGGGHGMVSKTLLAGVPLVVVPGG MUL_3383|M.ulcerans_Agy99 --VTPSWAAVGLGSQAELLTHADVVICGGGHGMVSKTLLAGVPLVVVPGG MAV_3631|M.avium_104 --AAPPWAVVGLGSQAELLRHADVVVCGGGHGMVAKTLLAGVPLVAVPGG Mb2759c|M.bovis_AF2122/97 --TVPPWAVAGLGSQAELLTRADLVICGGGHGMVAKTLLAGVPMVVVPGG Rv2739c|M.tuberculosis_H37Rv --TVPPWAVAGLGSQAELLTRADLVICGGGHGMVAKTLLAGVPMVVVPGG MLBr_00985|M.leprae_Br4923 --TVPSWAVAGLVHQTKLLAHADVVICGGGHGMVAKTLLAGVPLVVVPGG MAB_3062c|M.abscessus_ATCC_199 --GLPSWAIAGLARQDLLLSGADLAVCGGGHGFLSKALLAGVPTVVVPGG TH_4587|M.thermoresistible__bu GPVPPHVEVHASVPQLQVLRHASVFVSHAGMGSVMEALAHRVPIVAVPQM . : :* : : .* * .:* :* .** Mvan_1905|M.vanbaalenii_PYR-1 RDQFEVARRAEVARCGTRLPAKRLSAPRLRNKIREAMG---LTSGARAVA Mflv_0466|M.gilvum_PYR-GCK RDQFEVARRVELAGCGTRLPAGKLSVGRLRTAVKTAAT---MTGGAARVA MSMEG_2342|M.smegmatis_MC2_155 RDQAEVARRVQMARCGTRLPAKHLSAARLRRKVRQAMA---MSDGARRVA MMAR_1974|M.marinum_M GDQWEIANRVVRQ--GSARLIRPLGAEALAAAVNEVLS---SPGYREAAQ MUL_3383|M.ulcerans_Agy99 GDQWEIANRVVRQ--GSARLIRPLGADALAAAVNEVLS---SPGYREAAQ MAV_3631|M.avium_104 GDQWEIANRVVRQ--GSARLIRPLSADALVAAVNEVLS---SPGYRAAAQ Mb2759c|M.bovis_AF2122/97 GDQWEIANRVVRQ--GSAVLIRPLTADALVAAVNEVLS---SPRFREAAR Rv2739c|M.tuberculosis_H37Rv GDQWEIANRVVRQ--GSAVLIRPLTADALVAAVNEVLS---SPRFREAAR MLBr_00985|M.leprae_Br4923 GDQWEMANRVVRQ--GSAQLIRPLTAAALLAAVNKVLS---SPDYREAAQ MAB_3062c|M.abscessus_ATCC_199 GDQWELANRVVRQ--GSAELVRPLSRDSLASAIGRVLG---EPRYREAAR TH_4587|M.thermoresistible__bu TEQQANADRIAELNLGVRLGRDEITADRLRSAVERVAGSATIAAAVRTMH :* * * * : * : . . Mvan_1905|M.vanbaalenii_PYR-1 DGFAATGGVARGADLFEHLVGGN------- Mflv_0466|M.gilvum_PYR-GCK AGFAATGGVARGADVVESRLVARCALPEEQ MSMEG_2342|M.smegmatis_MC2_155 AGFAATGGVVRGADLIEQQVFSSEMRM--- MMAR_1974|M.marinum_M RAAASIADVADPVQVCHEALALAG------ MUL_3383|M.ulcerans_Agy99 RAAASIADVADPVQVCHEALALAG------ MAV_3631|M.avium_104 RAAAGIADVADPVRVCREALAG-------- Mb2759c|M.bovis_AF2122/97 RAAASVAGAADPVRVCHDALALAG------ Rv2739c|M.tuberculosis_H37Rv RAAASVAGAADPVRVCHDALALAG------ MLBr_00985|M.leprae_Br4923 RAAISIAGVADPVQVCHEALGLAG------ MAB_3062c|M.abscessus_ATCC_199 RAAAGAIAVEDPVRVCQDVLAALR------ TH_4587|M.thermoresistible__bu DAITAAGGAAAAADIVEDVLTRSR------ . . . . : . :