For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
AENIDVHSVAHSDIGEVYTVMKFAMASYGTRGDIEPAVAVGRELQRRGHEVRMAVPPDLIGFAGSVGLSA VPYGIHVGPQLDEYRDLWTSWTRHFWRLQDLVALCRQALKLVTEQWSEMSETLVSVAEGADLLSTSVGYE EPAANVAEFYGIPLVALHTMPWRPNGQLFPVLPPMLTRTGMTAYDWLTWRVTKGAEDAQRRHLGLPQATS PSPQRIGQRNSLEIQAYDAVCFRGLAEEWAKYGGRRPFVGALTMELTTSADDEVMSWIASGPPPICFASG SIPVESPAETVEMIGSACAELGERALVCAGATDFSGVQTSPHVKLVGVVNYAAVFPVSRAIVHHGGSGTT AASLRAGVPTLILWTVGDQPFWGNQLRRMGVGASRRFSTTTRDSLVSDLRTILTPECAARARAIAPHMSK PHDSVSKAADLLEAKASHP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4112c | - | - | 100% (440) | putative glycosyltransferase GtfA |
| M. abscessus ATCC 19977 | MAB_4107c | - | e-146 | 61.02% (413) | glycosyltransferase GtfA |
| M. abscessus ATCC 19977 | MAB_4104 | - | e-144 | 60.53% (418) | putative glycosyltransferase GtfB |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1551 | - | 1e-136 | 59.09% (418) | glycosyltransferase |
| M. gilvum PYR-GCK | Mflv_3984 | - | 2e-06 | 26.77% (310) | UDP-glucuronosyl/UDP-glucosyltransferase |
| M. tuberculosis H37Rv | Rv1524 | - | 1e-136 | 59.09% (418) | glycosyltransferase |
| M. leprae Br4923 | MLBr_02348 | - | 1e-127 | 55.61% (419) | putative glycosyl transferase |
| M. marinum M | MMAR_2353 | - | 1e-131 | 54.68% (417) | UDP-glycosyltransferase |
| M. avium 104 | MAV_3265 | - | 1e-156 | 64.16% (413) | glycosyl transferase |
| M. smegmatis MC2 155 | MSMEG_0385 | - | 1e-173 | 69.93% (409) | glycosyl transferase |
| M. thermoresistible (build 8) | TH_1989 | - | 4e-50 | 65.96% (141) | Glycosyltransferase family protein 28 |
| M. ulcerans Agy99 | MUL_1529 | - | 1e-104 | 51.55% (355) | UDP-glycosyltransferase |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1551|M.bovis_AF2122/97 ---------------------MKFVVASYGTRGDIEPCAAVGLELQRRGH
Rv1524|M.tuberculosis_H37Rv ---------------------MKFVVASYGTRGDIEPCAAVGLELQRRGH
MMAR_2353|M.marinum_M ---------------------MKFALAINGTRGDVEPCAALGRELSRRGH
MUL_1529|M.ulcerans_Agy99 -------------------------MSNRALHSGGNYRAEATKDAS----
MLBr_02348|M.leprae_Br4923 ---------------------MKFTLAASGSRGDVEPFAALGLELQRRGH
MAB_4112c|M.abscessus_ATCC_199 MAENIDVHSVAHSDIGEVYTVMKFAMASYGTRGDIEPAVAVGRELQRRGH
MSMEG_0385|M.smegmatis_MC2_155 -------------------------MASYGTRGDVEPAVAVARELRRRGH
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAV_3265|M.avium_104 ---------------------MKCVLASYGTRGDIEPSVVVARELQRRGH
Mflv_3984|M.gilvum_PYR-GCK ---------------------MRVAVVAGPDPGHAFPALELCRRFRAAGD
Mb1551|M.bovis_AF2122/97 DVCLAVPPNLIGFVETAGLSAVAYGSRDSQEQLDEQ------FLHNAWKL
Rv1524|M.tuberculosis_H37Rv DVCLAVPPNLIGFVETAGLSAVAYGSRDSQEQLDEQ------FLHNAWKL
MMAR_2353|M.marinum_M EVRVAVPPNLTGLAAAAGLEAVPYGP-DTDELLNDE-----DNLQEFWKP
MUL_1529|M.ulcerans_Agy99 ----QYPPNLTGVAAAAGLEAVPYCP-DTDELLNDE-----DNLQEFWKP
MLBr_02348|M.leprae_Br4923 EVRIGVPPDMLRFVESAGLAAVAYGP-DTQEFLARDT---YSQWRQWWKI
MAB_4112c|M.abscessus_ATCC_199 EVRMAVPPDLIGFAGSVGLSAVPYGI-HVGPQLDEYRDLWTSWTRHFWRL
MSMEG_0385|M.smegmatis_MC2_155 DVCIAVPPDLVRFAEDAGLSATSYGM-EVEPQLDAYRDIWTSWARKLWRL
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAV_3265|M.avium_104 DMIMAVPPDSVSFTEAAGLTAVPYGL-DSQAWLDVYRNFWTSFFRGFWKM
Mflv_3984|M.gilvum_PYR-GCK APTLLTGTRWLDVARGEGVDAVELDGLDPTAFDDDT--------------
Mb1551|M.bovis_AF2122/97 QNPIKLLREAMAPVTEGWAELSAMLTPVAAGADLLLTG-QIYQEVVANVA
Rv1524|M.tuberculosis_H37Rv QNPIKLLREAMAPVTEGWAELSAMLTPVAAGADLLLTG-QIYQEVVANVA
MMAR_2353|M.marinum_M QTSIKLVREGISDLRQAWSDMAGTLKTLADGADLVLTG-MIHQGIALNAA
MUL_1529|M.ulcerans_Agy99 QTSIKLVREGISDLRQAWSDMAGTLKTLADGADLVLTG-MIHQGIALNAA
MLBr_02348|M.leprae_Br4923 LPPIKALQQ----LRQAWADMATDLKSLADGADLVMTG-VVYQGVVANVA
MAB_4112c|M.abscessus_ATCC_199 QDLVALCRQALKLVTEQWSEMSETLVSVAEGADLLSTS-VGYEEPAANVA
MSMEG_0385|M.smegmatis_MC2_155 QDFVNLCREALGVTISQWEDIGKTLVTLADGADLLTTG-VGFEQPAANVA
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAV_3265|M.avium_104 GEMRGMWREMWDLSDQCWAQMNTTLLSLADGADLLFAG-QSYQEPAANVA
Mflv_3984|M.gilvum_PYR-GCK DAGEKIHRRAARMAVLNRARIGELSPDLVVSDSITVCGGLAADLLGVPWV
Mb1551|M.bovis_AF2122/97 EHHGIPLAALHFYPVRANGEIAFPARLPAPLVRSTITAIDWLYWRMTKGV
Rv1524|M.tuberculosis_H37Rv EHHGIPLAALHFYPVRANGEIAFPARLPAPLVRSTITAIDWLYWRMTKGV
MMAR_2353|M.marinum_M EYYGIPLATMHFLPSRVNSRVIP--ILSPRLNRSVISALWWVHWRVTKNP
MUL_1529|M.ulcerans_Agy99 EYYGIPLATMHFLPSRVNSRVIP--ILSPRLNRSVISALWWVHWRVTKNP
MLBr_02348|M.leprae_Br4923 EYYGIPFGVLHFVPARVNGKIIP--SLPSPLNRAILATVWRAHWLLAKKP
MAB_4112c|M.abscessus_ATCC_199 EFYGIPLVALHTMPWRPNGQLFP--VLPPMLTRTGMTAYDWLTWRVTKGA
MSMEG_0385|M.smegmatis_MC2_155 EYYGIPLIALHTFPWRPNGRLVP--AIPPLLTRSAMNVYDWLGWRLTKQA
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAV_3265|M.avium_104 EYYDLPLATLHHVPMRPNGQVVS--VLPAPLARSAMTAFDWFCWRLNKKV
Mflv_3984|M.gilvum_PYR-GCK ELNTHPLYRPSRGLPPVGSGLAPGVGLRGRARDAVLRALTARSWRAGLRQ
Mb1551|M.bovis_AF2122/97 EDAQRRELGLPKASTPAPRRMAVRGSLEIQAYDALCFPGLAAEW---GGR
Rv1524|M.tuberculosis_H37Rv EDAQRRELGLPKASTPAPRRMAVRGSLEIQAYDALCFPGLAAEW---GGR
MMAR_2353|M.marinum_M EEAQRRELGMAKASSSSTSRILKGRSLEIQAYDELCFPGLAAEWAEWGDR
MUL_1529|M.ulcerans_Agy99 EEAQRRELGMAKASSSSTSRILKGRSLEIQAYDELCFPGLAAEWAEWGDR
MLBr_02348|M.leprae_Br4923 EDAQRRELGLPKATSLSTRRIVKRGALEIQAYDELCFPGLAAEWAEYGDR
MAB_4112c|M.abscessus_ATCC_199 EDAQRRHLGLPQATSPSPQRIGQRNSLEIQAYDAVCFRGLAEEWAKYGGR
MSMEG_0385|M.smegmatis_MC2_155 EDAQRRELGLPMATSAARQRMAERGVLEIQAYDAISFPGLADEWARYGAR
TH_1989|M.thermoresistible__bu --------------------------------------------------
MAV_3265|M.avium_104 EDAQRRELGLPKATGPSPRRIAERGSLEIQAYDEVCFPGLAEEWAKWDGQ
Mflv_3984|M.gilvum_PYR-GCK RAAARVEIGLPGDDPGPVRRLIAT------------LPALEVPRPDWPAE
Mb1551|M.bovis_AF2122/97 RPFVGALTMESATDADDEVASWIAADTPPIYFGFGSMPIGSLADRVAMIS
Rv1524|M.tuberculosis_H37Rv RPFVGALTMESATDADDEVASWIAADTPPIYFGFGSMPIGSLADRVAMIS
MMAR_2353|M.marinum_M RPFVGALTLEMPTESDNEVLSWIASGTPPIYFGFGSMPVESPAATIAMIS
MUL_1529|M.ulcerans_Agy99 RPFVGALTLEMPTESDNEVLSWIASGTPPIYFGFGSMPVESPAATIAIIS
MLBr_02348|M.leprae_Br4923 RPFVGALTLELPTAADNEVLSWIAAGTPPIYFGFGSMPIVSPTDTVAMIA
MAB_4112c|M.abscessus_ATCC_199 RPFVGALTMELTTSADDEVMSWIASGPPPICFASGSIPVESPAETVEMIG
MSMEG_0385|M.smegmatis_MC2_155 RPFVGTLTMELATADDSEVTSWIAHGTPPICFGFGSIPVESPAETIDMIA
TH_1989|M.thermoresistible__bu -----------------------------------------------MFA
MAV_3265|M.avium_104 RPFVGTLTMELTTEADDEVMSWIRGGTPPICFGFGSMPVESPADTVDMIG
Mflv_3984|M.gilvum_PYR-GCK AVVVGPLHFEPTT----ELLAVPAGGGPLVVVAPSTATTGAGGMAELALN
:
Mb1551|M.bovis_AF2122/97 AACAELGERALICSGPSDATGI-PQFDHVKVVRVVSHAAVFPTCRAVVHH
Rv1524|M.tuberculosis_H37Rv AACAELGERALICSGPSDATGI-PQFDHVKVVRVVSHAAVFPTCRAVVHH
MMAR_2353|M.marinum_M AACAELGERALICTGSNDLGGL-QAPENVKLVSGVSHAAVFPACRAVVHH
MUL_1529|M.ulcerans_Agy99 AACAELGERALICTGSNDLGGL-QAPENVKLVSGVSHAAVFPACCAVVHH
MLBr_02348|M.leprae_Br4923 AACADLGERALISVKPKDLTQV-PKFDHVKIVTSVSHAAVFPACRAVVHH
MAB_4112c|M.abscessus_ATCC_199 SACAELGERALVCAGATDFSGV-QTSPHVKLVGVVNYAAVFPVSRAIVHH
MSMEG_0385|M.smegmatis_MC2_155 SACAELGERALVCAGGTDFGDS-PRFEHVKVAGTVNYATVFPVCRAVVHH
TH_1989|M.thermoresistible__bu SVCSRLGERALICAGGTDIDGV-PEYGHVKVVGAVNYARVFPACRAIVHH
MAV_3265|M.avium_104 TACAQLGERALLCAGRSDFSGV-PAPDHVKVVGPVNYATIFPACRAVVHH
Mflv_3984|M.gilvum_PYR-GCK TLVPGDTLPPGARVAVSQLDGPDSAVPPWAVVGLGRQDELLARADLLICG
: . . .: :. ::. . ::
Mb1551|M.bovis_AF2122/97 GGAGTTAAGLRAGIPTLILWVTSDQPIWAAQIKQLKVGRGRRFSSATKES
Rv1524|M.tuberculosis_H37Rv GGAGTTAAGLRAGIPTLILWVTSDQPIWAAQIKQLKVGRGRRFSSATKES
MMAR_2353|M.marinum_M GGAGTTAAGMRAGIPTLILWIWIEQPIWLAQIKRLKIGSGRRLASTTKET
MUL_1529|M.ulcerans_Agy99 GGAGTTAAGMRAGIPTLILWIWIEQPIWLAQIKRLKIGSGRRLASTTKET
MLBr_02348|M.leprae_Br4923 GGAGTTAASLRAGVPTLILWIFIEQPVWAAQIKRLKVGAGRRFSATTQRS
MAB_4112c|M.abscessus_ATCC_199 GGSGTTAASLRAGVPTLILWTVGDQPFWGNQLRRMGVGASRRFSTTTRDS
MSMEG_0385|M.smegmatis_MC2_155 GGSGTTAASLRAGVPTLTLWTAGDQPFWGAQLKKLKVGASRRFSATTRDT
TH_1989|M.thermoresistible__bu GGSGTTAAVLRAGVPSLVTWSSADQPYWGNQVKRLKVGTSRRFSHTTPDT
MAV_3265|M.avium_104 GGSGTTAASLRAGVPTLILSMDANQTIWGAQLKRLKVGATRRFSATDRDS
Mflv_3984|M.gilvum_PYR-GCK GGHGTVAKSLLAGVPMVVVPGGGDQ--WEIANRLVRQGSAQLVRPLSAES
** **.* : **:* : :* * : : * : . :
Mb1551|M.bovis_AF2122/97 LIADLRTILA-PDYVTRAREIASRMTKPAASVTATADLLEDAARRAR---
Rv1524|M.tuberculosis_H37Rv LIADLRTILA-PDYVTRAREIASRMTKPAASVTATADLLEDAARRAR---
MMAR_2353|M.marinum_M LVSDLRCILG-PDYVARARTIANEMSKPGESATRAADLLENEVSVS----
MUL_1529|M.ulcerans_Agy99 LVSDLRCILG-PDYVARP---------PG--LRRC---------------
MLBr_02348|M.leprae_Br4923 LAADLRTILA-PQYATRAREVANRMSKPDESVNAAADLLEDKASRNKSRT
MAB_4112c|M.abscessus_ATCC_199 LVSDLRTILT-PECAARARAIAPHMSKPHDSVSKAADLLEAKASHP----
MSMEG_0385|M.smegmatis_MC2_155 LVSDLRRILS-PEYAVKAREVATRMTNPAESVSRAADLIEQNLDPTRRS-
TH_1989|M.thermoresistible__bu LVADLRRILT-PDYAVRARAVAARMTDPADSVVRAADLFETAVECAPGVA
MAV_3265|M.avium_104 LVQDLRKILA-PDYARRAREIAARMTKPADSVMKAADVVEDFVQSRSRTG
Mflv_3984|M.gilvum_PYR-GCK LAAAVREVLGSPSYREAAVRAGAGVADVADPVRVCHDALGAPRKLGPCG-
* :* :* *. .
Mb1551|M.bovis_AF2122/97 -----
Rv1524|M.tuberculosis_H37Rv -----
MMAR_2353|M.marinum_M -----
MUL_1529|M.ulcerans_Agy99 -----
MLBr_02348|M.leprae_Br4923 RYQDC
MAB_4112c|M.abscessus_ATCC_199 -----
MSMEG_0385|M.smegmatis_MC2_155 -----
TH_1989|M.thermoresistible__bu HRE--
MAV_3265|M.avium_104 RS---
Mflv_3984|M.gilvum_PYR-GCK -----