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M. abscessus ATCC 19977 MAB_4107c (-)

annotation: glycosyltransferase GtfA
coordinates: 4166752 - 4168020
length: 422

KFVLASYGTRGDIEPSVVVARELQRRGHDVVMAVPPDLISFTESAGLETVSYGLDTKTWLDVYRNFWTFF
FHTFWKVREIRTMWRQMWELSDECWAQMNTTLMSAAQGADVLFAGQSYQEPAANVAEYHDIPLVTLHHIP
MRPNGQLVTILPSRLGRAAMRAFDWVSWRLNKKVEDAQRRELRLPKASSPSPQRIAERRSLEIQGYDSVC
FPGLATEWAKWNGLRPFVGSLTMAMTQEADEEVASWIAGGTPPIFFGFGSMPVESPSAALEMIGSACAEL
GERALIGAGWSDFGGAQLPEHVKVVGAVNYATVFPACRAVVHHGGSGTTAASLRAGVPTLILSMDANQTL
WGGQVKKLKVGTTRRFSTTTRESLVADLRRILASDYADRARELAAGMTKPGESAVAAADAMERFAQARCS
A*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_4107c--100% (422)glycosyltransferase GtfA
M. abscessus ATCC 19977MAB_4112c-e-14661.02% (413) putative glycosyltransferase GtfA
M. abscessus ATCC 19977MAB_4694c-e-14560.28% (423) glycosyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1551-1e-13057.14% (420) glycosyltransferase
M. gilvum PYR-GCKMflv_3984-6e-0726.54% (309) UDP-glucuronosyl/UDP-glucosyltransferase
M. tuberculosis H37RvRv1524-1e-13057.14% (420) glycosyltransferase
M. leprae Br4923MLBr_02348-1e-12253.55% (422) putative glycosyl transferase
M. marinum MMMAR_2353-1e-12554.72% (413) UDP-glycosyltransferase
M. avium 104MAV_3265-0.076.37% (419) glycosyl transferase
M. smegmatis MC2 155MSMEG_0389-0.076.30% (422) glycosyl transferase
M. thermoresistible (build 8)TH_1989-1e-4666.67% (141) Glycosyltransferase family protein 28
M. ulcerans Agy99MUL_1529-1e-10252.68% (355) UDP-glycosyltransferase
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Mb1551|M.bovis_AF2122/97            MKFVVASYGTRGDIEPCAAVGLELQRRGHDVCLAVPPNLIGFVETAGLSA
Rv1524|M.tuberculosis_H37Rv         MKFVVASYGTRGDIEPCAAVGLELQRRGHDVCLAVPPNLIGFVETAGLSA
MMAR_2353|M.marinum_M               MKFALAINGTRGDVEPCAALGRELSRRGHEVRVAVPPNLTGLAAAAGLEA
MUL_1529|M.ulcerans_Agy99           ----MSNRALHSGGNYRAEATKDAS--------QYPPNLTGVAAAAGLEA
MLBr_02348|M.leprae_Br4923          MKFTLAASGSRGDVEPFAALGLELQRRGHEVRIGVPPDMLRFVESAGLAA
MAB_4107c|M.abscessus_ATCC_199      MKFVLASYGTRGDIEPSVVVARELQRRGHDVVMAVPPDLISFTESAGLET
MSMEG_0389|M.smegmatis_MC2_155      MKFVLASYGTRGDIEPSVVVGRELQSRGHTVLMAVPPDLIEFTEAANLRT
MAV_3265|M.avium_104                MKCVLASYGTRGDIEPSVVVARELQRRGHDMIMAVPPDSVSFTEAAGLTA
TH_1989|M.thermoresistible__bu      --------------------------------------------------
Mflv_3984|M.gilvum_PYR-GCK          MRVAVVAGPDPGHAFPALELCRRFRAAGDAPTLLTGTRWLDVARGEGVDA
                                                                                      

Mb1551|M.bovis_AF2122/97            VAYGSRDSQEQLDEQ------FLHNAWKLQNPIKLLREAMAPVTEGWAEL
Rv1524|M.tuberculosis_H37Rv         VAYGSRDSQEQLDEQ------FLHNAWKLQNPIKLLREAMAPVTEGWAEL
MMAR_2353|M.marinum_M               VPYGP-DTDELLNDE-----DNLQEFWKPQTSIKLVREGISDLRQAWSDM
MUL_1529|M.ulcerans_Agy99           VPYCP-DTDELLNDE-----DNLQEFWKPQTSIKLVREGISDLRQAWSDM
MLBr_02348|M.leprae_Br4923          VAYGP-DTQEFLARDT---YSQWRQWWKILPPIKALQQ----LRQAWADM
MAB_4107c|M.abscessus_ATCC_199      VSYGL-DTKTWLDVYRNFWTFFFHTFWKVREIRTMWRQMWELSDECWAQM
MSMEG_0389|M.smegmatis_MC2_155      VAYGL-DTKTWLDIYRNFWTFALHRFWKAREIRSLWREMWDLSDECWAQM
MAV_3265|M.avium_104                VPYGL-DSQAWLDVYRNFWTSFFRGFWKMGEMRGMWREMWDLSDQCWAQM
TH_1989|M.thermoresistible__bu      --------------------------------------------------
Mflv_3984|M.gilvum_PYR-GCK          VELDGLDPTAFDDDT--------------DAGEKIHRRAARMAVLNRARI
                                                                                      

Mb1551|M.bovis_AF2122/97            SAMLTPVAAGADLLLTG-QIYQEVVANVAEHHGIPLAALHFYPVRANGEI
Rv1524|M.tuberculosis_H37Rv         SAMLTPVAAGADLLLTG-QIYQEVVANVAEHHGIPLAALHFYPVRANGEI
MMAR_2353|M.marinum_M               AGTLKTLADGADLVLTG-MIHQGIALNAAEYYGIPLATMHFLPSRVNSRV
MUL_1529|M.ulcerans_Agy99           AGTLKTLADGADLVLTG-MIHQGIALNAAEYYGIPLATMHFLPSRVNSRV
MLBr_02348|M.leprae_Br4923          ATDLKSLADGADLVMTG-VVYQGVVANVAEYYGIPFGVLHFVPARVNGKI
MAB_4107c|M.abscessus_ATCC_199      NTTLMSAAQGADVLFAG-QSYQEPAANVAEYHDIPLVTLHHIPMRPNGQL
MSMEG_0389|M.smegmatis_MC2_155      NATLRSVAADADVLFAG-QSYQEPAANVAEFYDVPLVTLHHIPMRPNGRL
MAV_3265|M.avium_104                NTTLLSLADGADLLFAG-QSYQEPAANVAEYYDLPLATLHHVPMRPNGQV
TH_1989|M.thermoresistible__bu      --------------------------------------------------
Mflv_3984|M.gilvum_PYR-GCK          GELSPDLVVSDSITVCGGLAADLLGVPWVELNTHPLYRPSRGLPPVGSGL
                                                                                      

Mb1551|M.bovis_AF2122/97            AFPARLPAPLVRSTITAIDWLYWRMTKGVEDAQRRELGLPKASTPAPRRM
Rv1524|M.tuberculosis_H37Rv         AFPARLPAPLVRSTITAIDWLYWRMTKGVEDAQRRELGLPKASTPAPRRM
MMAR_2353|M.marinum_M               IP--ILSPRLNRSVISALWWVHWRVTKNPEEAQRRELGMAKASSSSTSRI
MUL_1529|M.ulcerans_Agy99           IP--ILSPRLNRSVISALWWVHWRVTKNPEEAQRRELGMAKASSSSTSRI
MLBr_02348|M.leprae_Br4923          IP--SLPSPLNRAILATVWRAHWLLAKKPEDAQRRELGLPKATSLSTRRI
MAB_4107c|M.abscessus_ATCC_199      VT--ILPSRLGRAAMRAFDWVSWRLNKKVEDAQRRELRLPKASSPSPQRI
MSMEG_0389|M.smegmatis_MC2_155      VT--FLPPVLARASMTAFDWFAWRLNKKVEDAQRRDLGLPKATGPSTQRI
MAV_3265|M.avium_104                VS--VLPAPLARSAMTAFDWFCWRLNKKVEDAQRRELGLPKATGPSPRRI
TH_1989|M.thermoresistible__bu      --------------------------------------------------
Mflv_3984|M.gilvum_PYR-GCK          APGVGLRGRARDAVLRALTARSWRAGLRQRAAARVEIGLPGDDPGPVRRL
                                                                                      

Mb1551|M.bovis_AF2122/97            AVRGSLEIQAYDALCFPGLAAEW---GGRRPFVGALTMESATDADDEVAS
Rv1524|M.tuberculosis_H37Rv         AVRGSLEIQAYDALCFPGLAAEW---GGRRPFVGALTMESATDADDEVAS
MMAR_2353|M.marinum_M               LKGRSLEIQAYDELCFPGLAAEWAEWGDRRPFVGALTLEMPTESDNEVLS
MUL_1529|M.ulcerans_Agy99           LKGRSLEIQAYDELCFPGLAAEWAEWGDRRPFVGALTLEMPTESDNEVLS
MLBr_02348|M.leprae_Br4923          VKRGALEIQAYDELCFPGLAAEWAEYGDRRPFVGALTLELPTAADNEVLS
MAB_4107c|M.abscessus_ATCC_199      AERRSLEIQGYDSVCFPGLATEWAKWNGLRPFVGSLTMAMTQEADEEVAS
MSMEG_0389|M.smegmatis_MC2_155      ADRMSLEVQAYDEVCFPGLAEEWAKWGELRPYVGTLTMELTTPADEEVSS
MAV_3265|M.avium_104                AERGSLEIQAYDEVCFPGLAEEWAKWDGQRPFVGTLTMELTTEADDEVMS
TH_1989|M.thermoresistible__bu      --------------------------------------------------
Mflv_3984|M.gilvum_PYR-GCK          IAT------------LPALEVPRPDWPAEAVVVGPLHFEPTT----ELLA
                                                                                      

Mb1551|M.bovis_AF2122/97            WIAADTPPIYFGFGSMPIGSLADRVAMISAACAELGERALICSGPSDATG
Rv1524|M.tuberculosis_H37Rv         WIAADTPPIYFGFGSMPIGSLADRVAMISAACAELGERALICSGPSDATG
MMAR_2353|M.marinum_M               WIASGTPPIYFGFGSMPVESPAATIAMISAACAELGERALICTGSNDLGG
MUL_1529|M.ulcerans_Agy99           WIASGTPPIYFGFGSMPVESPAATIAIISAACAELGERALICTGSNDLGG
MLBr_02348|M.leprae_Br4923          WIAAGTPPIYFGFGSMPIVSPTDTVAMIAAACADLGERALISVKPKDLTQ
MAB_4107c|M.abscessus_ATCC_199      WIAGGTPPIFFGFGSMPVESPSAALEMIGSACAELGERALIGAGWSDFGG
MSMEG_0389|M.smegmatis_MC2_155      WICGGTPPICFGFGSMPVESPADTVAMISSVCAELGERALICAGWSDFSD
MAV_3265|M.avium_104                WIRGGTPPICFGFGSMPVESPADTVDMIGTACAQLGERALLCAGRSDFSG
TH_1989|M.thermoresistible__bu      --------------------------MFASVCSRLGERALICAGGTDIDG
Mflv_3984|M.gilvum_PYR-GCK          VPAGGGPLVVVAPSTATTGAGGMAELALNTLVPGDTLPPGARVAVSQLDG
                                                               : :  .     .      .:   

Mb1551|M.bovis_AF2122/97            -IPQFDHVKVVRVVSHAAVFPTCRAVVHHGGAGTTAAGLRAGIPTLILWV
Rv1524|M.tuberculosis_H37Rv         -IPQFDHVKVVRVVSHAAVFPTCRAVVHHGGAGTTAAGLRAGIPTLILWV
MMAR_2353|M.marinum_M               -LQAPENVKLVSGVSHAAVFPACRAVVHHGGAGTTAAGMRAGIPTLILWI
MUL_1529|M.ulcerans_Agy99           -LQAPENVKLVSGVSHAAVFPACCAVVHHGGAGTTAAGMRAGIPTLILWI
MLBr_02348|M.leprae_Br4923          -VPKFDHVKIVTSVSHAAVFPACRAVVHHGGAGTTAASLRAGVPTLILWI
MAB_4107c|M.abscessus_ATCC_199      -AQLPEHVKVVGAVNYATVFPACRAVVHHGGSGTTAASLRAGVPTLILSM
MSMEG_0389|M.smegmatis_MC2_155      -VALADHVKVVGAVNYATVFPGCRAVVHHGGSGTTAASLRAGLPTLVLSM
MAV_3265|M.avium_104                -VPAPDHVKVVGPVNYATIFPACRAVVHHGGSGTTAASLRAGVPTLILSM
TH_1989|M.thermoresistible__bu      -VPEYGHVKVVGAVNYARVFPACRAIVHHGGSGTTAAVLRAGVPSLVTWS
Mflv_3984|M.gilvum_PYR-GCK          PDSAVPPWAVVGLGRQDELLARADLLICGGGHGTVAKSLLAGVPMVVVPG
                                             :*       ::. .  ::  ** **.*  : **:* ::   

Mb1551|M.bovis_AF2122/97            TSDQPIWAAQIKQLKVGRGRRFSSATKESLIADLRTILA-PDYVTRAREI
Rv1524|M.tuberculosis_H37Rv         TSDQPIWAAQIKQLKVGRGRRFSSATKESLIADLRTILA-PDYVTRAREI
MMAR_2353|M.marinum_M               WIEQPIWLAQIKRLKIGSGRRLASTTKETLVSDLRCILG-PDYVARARTI
MUL_1529|M.ulcerans_Agy99           WIEQPIWLAQIKRLKIGSGRRLASTTKETLVSDLRCILG-PDYVARP---
MLBr_02348|M.leprae_Br4923          FIEQPVWAAQIKRLKVGAGRRFSATTQRSLAADLRTILA-PQYATRAREV
MAB_4107c|M.abscessus_ATCC_199      DANQTLWGGQVKKLKVGTTRRFSTTTRESLVADLRRILA-SDYADRAREL
MSMEG_0389|M.smegmatis_MC2_155      DANQALWGAQIKRLKVGTTRRFSKTNRRTLIADLRTILD-PAYAARAQAL
MAV_3265|M.avium_104                DANQTIWGAQLKRLKVGATRRFSATDRDSLVQDLRKILA-PDYARRAREI
TH_1989|M.thermoresistible__bu      SADQPYWGNQVKRLKVGTSRRFSHTTPDTLVADLRRILT-PDYAVRARAV
Mflv_3984|M.gilvum_PYR-GCK          GGDQ--WEIANRLVRQGSAQLVRPLSAESLAAAVREVLGSPSYREAAVRA
                                      :*  *    : :: *  : .      :*   :* :*  . *   .   

Mb1551|M.bovis_AF2122/97            ASRMTKPAASVTATADLLEDAARRAR--------
Rv1524|M.tuberculosis_H37Rv         ASRMTKPAASVTATADLLEDAARRAR--------
MMAR_2353|M.marinum_M               ANEMSKPGESATRAADLLENEVSVS---------
MUL_1529|M.ulcerans_Agy99           ------PG--LRRC--------------------
MLBr_02348|M.leprae_Br4923          ANRMSKPDESVNAAADLLEDKASRNKSRTRYQDC
MAB_4107c|M.abscessus_ATCC_199      AAGMTKPGESAVAAADAMERFAQARCSA------
MSMEG_0389|M.smegmatis_MC2_155      ARGMTRPAESVVRAADVIEAFARSRCSA------
MAV_3265|M.avium_104                AARMTKPADSVMKAADVVEDFVQSRSRTGRS---
TH_1989|M.thermoresistible__bu      AARMTDPADSVVRAADLFETAVECAPGVAHRE--
Mflv_3984|M.gilvum_PYR-GCK          GAGVADVADPVRVCHDALGAPRKLGPCG------