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MKAVVASYGSRGDVEPCAAAARELLRRGHEVRVAAPPNLVGFLESAGLTTVAYGPDSHQQMGPAPNLVGD LAATAQHPITMVPKLIEHLTRVNAAKSETLTALADGADLLVVGFNEQAVAANVAEYFGIPLAGLHFFPAP ALPAGMLSTLATKAADDAQRQALGLPPASESVPQRVAEQGSLEIQAYDQIVLPGPPGRWVQADGRHPFIG ALTLQSPTDDDDAILAWIAEGAPPIYFGFGSTPLTSPAEQFAMISAACAQLGERALICAGPNDFGQMPHS HQVMVAPAVNHAAVFPACRAIVHHGGAGTTAAGLRAGIPMLIRWLWLDQPIWAAGIEELGVGVGQPFSAA TSESLAAGLGSILAAQYIARARTVADQMTPPAHSIAMAADLLEHTAHVDRRS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4949 | - | - | 100% (402) | glycosyltransferase |
| M. ulcerans Agy99 | MUL_1529 | - | 1e-87 | 47.44% (352) | UDP-glycosyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1551 | - | 1e-115 | 54.46% (415) | glycosyltransferase |
| M. gilvum PYR-GCK | Mflv_2592 | - | 1e-06 | 27.16% (243) | glycosyl transferase family protein |
| M. tuberculosis H37Rv | Rv1524 | - | 1e-115 | 54.46% (415) | glycosyltransferase |
| M. leprae Br4923 | MLBr_02348 | - | 1e-110 | 50.84% (415) | putative glycosyl transferase |
| M. abscessus ATCC 19977 | MAB_4112c | - | 2e-98 | 46.67% (420) | putative glycosyltransferase GtfA |
| M. marinum M | MMAR_0148 | - | 0.0 | 98.51% (402) | glycosyltransferase |
| M. avium 104 | MAV_2747 | - | 1e-130 | 59.09% (396) | rhamnosyltransferase RtfA |
| M. smegmatis MC2 155 | MSMEG_4740 | - | 1e-103 | 49.28% (414) | glycosyltransferase family protein 28 |
| M. thermoresistible (build 8) | TH_1989 | - | 2e-37 | 53.90% (141) | Glycosyltransferase family protein 28 |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4949|M.ulcerans_Agy99 ---------------------MKAVVASYGSRGDVEPCAAAARELLRRGH
MMAR_0148|M.marinum_M ---------------------MKAVVASYGSRGDVEPCAAAARELLRRGH
MAV_2747|M.avium_104 ---------------------MKIVLATYGSRGDVEPCAAVARELQGRGH
Mb1551|M.bovis_AF2122/97 ---------------------MKFVVASYGTRGDIEPCAAVGLELQRRGH
Rv1524|M.tuberculosis_H37Rv ---------------------MKFVVASYGTRGDIEPCAAVGLELQRRGH
MLBr_02348|M.leprae_Br4923 ---------------------MKFTLAASGSRGDVEPFAALGLELQRRGH
MSMEG_4740|M.smegmatis_MC2_155 ---------------------MKFVVAIHGTRGDIEPSATVATELRRRGH
MAB_4112c|M.abscessus_ATCC_199 MAENIDVHSVAHSDIGEVYTVMKFAMASYGTRGDIEPAVAVGRELQRRGH
TH_1989|M.thermoresistible__bu --------------------------------------------------
Mflv_2592|M.gilvum_PYR-GCK -----------------MNAMPDILITACPPVGHIGPLLNVAHGLVAHGH
MUL_4949|M.ulcerans_Agy99 EVRVAAPPNLVGFLESAGLT--TVAYGP-DSHQQMGPAPNLVG---DLAA
MMAR_0148|M.marinum_M EVRVAAPPNLVGFLESAGLT--TVAYGP-DSHQQMGPAANLVG---DFAA
MAV_2747|M.avium_104 DVRIALSPDQLGLAESAGLR--AVAYGP-DSREQINTAT-------DFVH
Mb1551|M.bovis_AF2122/97 DVCLAVPPNLIGFVETAGLS--AVAYGSRDSQEQLDEQFLHN------AW
Rv1524|M.tuberculosis_H37Rv DVCLAVPPNLIGFVETAGLS--AVAYGSRDSQEQLDEQFLHN------AW
MLBr_02348|M.leprae_Br4923 EVRIGVPPDMLRFVESAGLA--AVAYGP-DTQEFLARDTYS-------QW
MSMEG_4740|M.smegmatis_MC2_155 EVRMAVPPNLVPFVERIGLS--AESYGV-DSQQQLDADTFRD------FW
MAB_4112c|M.abscessus_ATCC_199 EVRMAVPPDLIGFAGSVGLS--AVPYGI-HVGPQLDEYRDLWTSWTRHFW
TH_1989|M.thermoresistible__bu --------------------------------------------------
Mflv_2592|M.gilvum_PYR-GCK RVTVLTSARHADKIRAVGADPRPLPYGADYDDARLDADLPGRAHTSGIAR
MUL_4949|M.ulcerans_Agy99 TAQHPITMVPKLIEHLTRVNAAKSETLTALADGADLLVVGFNEQAVAANV
MMAR_0148|M.marinum_M TAQHPITMVPKLIEHLTRVNAAKSETLTALADGADLLVVGFNEQAVAANV
MAV_2747|M.avium_104 TVQNPISALPQLTERVTAVWAAKSETLAALAAGADLLVAGMNEQRLAANV
Mb1551|M.bovis_AF2122/97 KLQNPIKLLREAMAPVTEGWAELSAMLTPVAAGADLLLTGQIYQEVVANV
Rv1524|M.tuberculosis_H37Rv KLQNPIKLLREAMAPVTEGWAELSAMLTPVAAGADLLLTGQIYQEVVANV
MLBr_02348|M.leprae_Br4923 RQWWKILPPIKALQQLRQAWADMATDLKSLADGADLVMTGVVYQGVVANV
MSMEG_4740|M.smegmatis_MC2_155 KIRNPVKAIREGREYMVGGWAEMSATVAALADGADVLLTGTTYQEVVANV
MAB_4112c|M.abscessus_ATCC_199 RLQDLVALCRQALKLVTEQWSEMSETLVSVAEGADLLSTSVGYEEPAANV
TH_1989|M.thermoresistible__bu --------------------------------------------------
Mflv_2592|M.gilvum_PYR-GCK INFDVEHVFVRPMPYQFSAVQELLAANSFDAVITDAFFLGVIPLLLDPTL
MUL_4949|M.ulcerans_Agy99 AEYFGIPLAGLHFFPAPA---------LPAGMLST----------LATKA
MMAR_0148|M.marinum_M AEYFGIPLAGLHFFPAPA---------LPAGMLST----------LATKA
MAV_2747|M.avium_104 AQRVGAPLAALHFFPADT---------LELGWIQS----------HVTAA
Mb1551|M.bovis_AF2122/97 AEHHGIPLAALHFYPVRANGEIAFPARLPAPLVRSTITAIDWLYWRMTKG
Rv1524|M.tuberculosis_H37Rv AEHHGIPLAALHFYPVRANGEIAFPARLPAPLVRSTITAIDWLYWRMTKG
MLBr_02348|M.leprae_Br4923 AEYYGIPFGVLHFVPARVNGKIIP--SLPSPLNRAILATVWRAHWLLAKK
MSMEG_4740|M.smegmatis_MC2_155 AESERIPLAALHYFPHRANSQILP-IRLPRRIVEPMWAVAEWGYWQILKS
MAB_4112c|M.abscessus_ATCC_199 AEFYGIPLVALHTMPWRPNGQLFP--VLPPMLTRTGMTAYDWLTWRVTKG
TH_1989|M.thermoresistible__bu --------------------------------------------------
Mflv_2592|M.gilvum_PYR-GCK ARPPIMAYSTTPLFLSSRDTAPAGPGILPMPGAVGRLRNRLLGLLSRAVL
MUL_4949|M.ulcerans_Agy99 ADDAQR-QALGLPPASESVPQRVAEQGSLEIQAYDQIVLPGPPGRWVQAD
MMAR_0148|M.marinum_M ADDAQR-QALGLPPALESVPQRVAEQGSLEIQAYDQIVLPGPPGRWVQAD
MAV_2747|M.avium_104 AEAAQR-QALGLPADAG-----QSDRAALEIQAYDELCVPGRAEQWATAG
Mb1551|M.bovis_AF2122/97 VEDAQR-RELGLPKASTPAPRRMAVRGSLEIQAYDALCFPGLAAEW---G
Rv1524|M.tuberculosis_H37Rv VEDAQR-RELGLPKASTPAPRRMAVRGSLEIQAYDALCFPGLAAEW---G
MLBr_02348|M.leprae_Br4923 PEDAQR-RELGLPKATSLSTRRIVKRGALEIQAYDELCFPGLAAEWAEYG
MSMEG_4740|M.smegmatis_MC2_155 AEDAQR-RELGLAPARSSSVNRIVSSGTLEIQAYDEVFFPGLRQEWR---
MAB_4112c|M.abscessus_ATCC_199 AEDAQR-RHLGLPQATSPSPQRIGQRNSLEIQAYDAVCFRGLAEEWAKYG
TH_1989|M.thermoresistible__bu --------------------------------------------------
Mflv_2592|M.gilvum_PYR-GCK LRPAHRSAERMLRAMGLPDLPVFVLECAILADRVIVPTVPDFEYPRRDLP
MUL_4949|M.ulcerans_Agy99 GRHPFIGALT-LQSPTDDDDAILAWIAEGAPPIYFGFGSTPLTSPAEQFA
MMAR_0148|M.marinum_M GRHPFVGALT-LQSPTDDDDAILAWIAEGAPPIYFGFGSTPLTSPAEQFA
MAV_2747|M.avium_104 HRRPFVGSLT-LGLPTGVDDEVLSWIADGTAPVYFGFGSTPVSSPAETVA
Mb1551|M.bovis_AF2122/97 GRRPFVGALT-MESATDADDEVASWIAADTPPIYFGFGSMPIGSLADRVA
Rv1524|M.tuberculosis_H37Rv GRRPFVGALT-MESATDADDEVASWIAADTPPIYFGFGSMPIGSLADRVA
MLBr_02348|M.leprae_Br4923 DRRPFVGALT-LELPTAADNEVLSWIAAGTPPIYFGFGSMPIVSPTDTVA
MSMEG_4740|M.smegmatis_MC2_155 GTRPFVGALT-LELPTDTDDDVTAWAASGKPPIYFGFGSMPVQSPADAVT
MAB_4112c|M.abscessus_ATCC_199 GRRPFVGALT-MELTTSADDEVMSWIASGPPPICFASGSIPVESPAETVE
TH_1989|M.thermoresistible__bu --------------------------------------------------
Mflv_2592|M.gilvum_PYR-GCK AHVRFVGAVSPLPGDDFIAPAWWGELYRGRPVVHVTQGTVDNADLTRLIE
MUL_4949|M.ulcerans_Agy99 MISAACAQLGERALICAGPNDFGQMPH--SHQVMVAPAVNHAAVFPACRA
MMAR_0148|M.marinum_M MISAACAQLGERALICAGPNDFGQMPH--SHQVMVAPAVNHAAVFPACRA
MAV_2747|M.avium_104 VISAACARVGERALICSGPNDFTGIPP--EDHVKIVPAVNHAAVFPACRA
Mb1551|M.bovis_AF2122/97 MISAACAELGERALICSGPSDATGIPQ--FDHVKVVRVVSHAAVFPTCRA
Rv1524|M.tuberculosis_H37Rv MISAACAELGERALICSGPSDATGIPQ--FDHVKVVRVVSHAAVFPTCRA
MLBr_02348|M.leprae_Br4923 MIAAACADLGERALISVKPKDLTQVPK--FDHVKIVTSVSHAAVFPACRA
MSMEG_4740|M.smegmatis_MC2_155 MISSVCTRLGERALISSGAWNLDAIPE--SDHVKVVGAVNHAKIFPLCRA
MAB_4112c|M.abscessus_ATCC_199 MIGSACAELGERALVCAGATDFSGVQT--SPHVKLVGVVNYAAVFPVSRA
TH_1989|M.thermoresistible__bu MFASVCSRLGERALICAGGTDIDGVPE--YGHVKVVGAVNYARVFPACRA
Mflv_2592|M.gilvum_PYR-GCK PTIEALAGEDVTVVVSTGGRPVSQIRTPLPANTFVAEFLPHDVLLPLVDV
. : . .::. : :. :. : : ::* .
MUL_4949|M.ulcerans_Agy99 IVHHGGAGTTAAGLRAGIPMLIRWLWLDQPIWAAGIEELGVGVGQPFSAA
MMAR_0148|M.marinum_M IVHHGGAGTTAAGLRAGIPMLIRWLWLDQPIWAAGIEELGVGVGQPFSAT
MAV_2747|M.avium_104 VVHHGGSGTTAAGLRAGVPMLILWLWLDQPVWAEAVSALEVGLARAFSAS
Mb1551|M.bovis_AF2122/97 VVHHGGAGTTAAGLRAGIPTLILWVTSDQPIWAAQIKQLKVGRGRRFSSA
Rv1524|M.tuberculosis_H37Rv VVHHGGAGTTAAGLRAGIPTLILWVTSDQPIWAAQIKQLKVGRGRRFSSA
MLBr_02348|M.leprae_Br4923 VVHHGGAGTTAASLRAGVPTLILWIFIEQPVWAAQIKRLKVGAGRRFSAT
MSMEG_4740|M.smegmatis_MC2_155 VVHHGGAGTTAAGLRAARPTLILWVGADQPVWAAAVKRLQAGTAERFSKV
MAB_4112c|M.abscessus_ATCC_199 IVHHGGSGTTAASLRAGVPTLILWTVGDQPFWGNQLRRMGVGASRRFSTT
TH_1989|M.thermoresistible__bu IVHHGGSGTTAAVLRAGVPSLVTWSSADQPYWGNQVKRLKVGTSRRFSHT
Mflv_2592|M.gilvum_PYR-GCK LVTNGGYGAVQRALAEGVPLVVAGDTEDKPEVAARVEYFGVGVNLRTGTP
:* :** *:. * . * :: ::* . : : .* .
MUL_4949|M.ulcerans_Agy99 TSESLAAGLGSILAAQYIARARTVADQMTPPAHSIAMAADLLEHTAHVDR
MMAR_0148|M.marinum_M TSESLAAGLGSILAAQYIARARTVAAQMTPPAHSIAMAADLLEHTAHVDR
MAV_2747|M.avium_104 TLDSLTADLRCVLDGRYHDRAREVATRMTKPGESVAAAADLLEDAARGG-
Mb1551|M.bovis_AF2122/97 TKESLIADLRTILAPDYVTRAREIASRMTKPAASVTATADLLEDAARRAR
Rv1524|M.tuberculosis_H37Rv TKESLIADLRTILAPDYVTRAREIASRMTKPAASVTATADLLEDAARRAR
MLBr_02348|M.leprae_Br4923 TQRSLAADLRTILAPQYATRAREVANRMSKPDESVNAAADLLEDKASRNK
MSMEG_4740|M.smegmatis_MC2_155 TPDSLLAGLQTVLTPRAALRARQIADEMTTPADSVRMTADLLEAAAARPM
MAB_4112c|M.abscessus_ATCC_199 TRDSLVSDLRTILTPECAARARAIAPHMSKPHDSVSKAADLLEAKASHP-
TH_1989|M.thermoresistible__bu TPDTLVADLRRILTPDYAVRARAVAARMTDPADSVVRAADLFETAVECAP
Mflv_2592|M.gilvum_PYR-GCK APQDLRDAVNAVLSDAGYRTRAGRLQAAYASRDSVTAIAALLDEVIPEQA
: * : :* . *: * *::
MUL_4949|M.ulcerans_Agy99 RS------
MMAR_0148|M.marinum_M RS------
MAV_2747|M.avium_104 --------
Mb1551|M.bovis_AF2122/97 --------
Rv1524|M.tuberculosis_H37Rv --------
MLBr_02348|M.leprae_Br4923 SRTRYQDC
MSMEG_4740|M.smegmatis_MC2_155 PA------
MAB_4112c|M.abscessus_ATCC_199 --------
TH_1989|M.thermoresistible__bu GVAHRE--
Mflv_2592|M.gilvum_PYR-GCK AAR-----