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MKFTLAASGSRGDVEPFAALGLELQRRGHEVRIGVPPDMLRFVESAGLAAVAYGPDTQEFLARDTYSQWR QWWKILPPIKALQQLRQAWADMATDLKSLADGADLVMTGVVYQGVVANVAEYYGIPFGVLHFVPARVNGK IIPSLPSPLNRAILATVWRAHWLLAKKPEDAQRRELGLPKATSLSTRRIVKRGALEIQAYDELCFPGLAA EWAEYGDRRPFVGALTLELPTAADNEVLSWIAAGTPPIYFGFGSMPIVSPTDTVAMIAAACADLGERALI SVKPKDLTQVPKFDHVKIVTSVSHAAVFPACRAVVHHGGAGTTAASLRAGVPTLILWIFIEQPVWAAQIK RLKVGAGRRFSATTQRSLAADLRTILAPQYATRAREVANRMSKPDESVNAAADLLEDKASRNKSRTRYQD C
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_02348 | - | - | 100% (421) | putative glycosyl transferase |
| M. leprae Br4923 | MLBr_00985 | - | 3e-05 | 24.18% (306) | putative glycosyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1551 | - | 1e-144 | 62.68% (418) | glycosyltransferase |
| M. gilvum PYR-GCK | Mflv_0466 | - | 5e-06 | 24.86% (346) | glycosyl transferase family protein |
| M. tuberculosis H37Rv | Rv1524 | - | 1e-144 | 62.68% (418) | glycosyltransferase |
| M. abscessus ATCC 19977 | MAB_4112c | - | 1e-127 | 55.61% (419) | putative glycosyltransferase GtfA |
| M. marinum M | MMAR_2353 | - | 1e-155 | 64.01% (414) | UDP-glycosyltransferase |
| M. avium 104 | MAV_3258 | - | 1e-144 | 61.11% (414) | glycosyltransferase family protein 28 |
| M. smegmatis MC2 155 | MSMEG_0385 | - | 1e-129 | 56.72% (409) | glycosyl transferase |
| M. thermoresistible (build 8) | TH_1989 | - | 1e-43 | 60.28% (141) | Glycosyltransferase family protein 28 |
| M. ulcerans Agy99 | MUL_1529 | - | 1e-128 | 62.22% (352) | UDP-glycosyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1905 | - | 4e-07 | 24.43% (352) | glycosyl transferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2353|M.marinum_M ---------------------MKFALAINGTRGDVEPCAALGRELSRRGH
MUL_1529|M.ulcerans_Agy99 -------------------------MSNRALHSGGNYRAEATKDAS----
MLBr_02348|M.leprae_Br4923 ---------------------MKFTLAASGSRGDVEPFAALGLELQRRGH
Mb1551|M.bovis_AF2122/97 ---------------------MKFVVASYGTRGDIEPCAAVGLELQRRGH
Rv1524|M.tuberculosis_H37Rv ---------------------MKFVVASYGTRGDIEPCAAVGLELQRRGH
MAV_3258|M.avium_104 ---------------------MRFALASYGTRGDIEPSAAVGRELLRRGH
MAB_4112c|M.abscessus_ATCC_199 MAENIDVHSVAHSDIGEVYTVMKFAMASYGTRGDIEPAVAVGRELQRRGH
MSMEG_0385|M.smegmatis_MC2_155 -------------------------MASYGTRGDVEPAVAVARELRRRGH
TH_1989|M.thermoresistible__bu --------------------------------------------------
Mflv_0466|M.gilvum_PYR-GCK --------------------MAVILAYTAPALGHLFPFCAVLQELARRGH
Mvan_1905|M.vanbaalenii_PYR-1 --------------------MATILAYTSPALGHLLPMGALLSELSRRGH
MMAR_2353|M.marinum_M EVRVAVPPNLTGLAAAAGLEAVPYGP-DTDELLNDE-----DNLQEFWK-
MUL_1529|M.ulcerans_Agy99 ----QYPPNLTGVAAAAGLEAVPYCP-DTDELLNDE-----DNLQEFWK-
MLBr_02348|M.leprae_Br4923 EVRIGVPPDMLRFVESAGLAAVAYGP-DTQEFLARDT---YSQWRQWWK-
Mb1551|M.bovis_AF2122/97 DVCLAVPPNLIGFVETAGLSAVAYGSRDSQEQLDEQ------FLHNAWK-
Rv1524|M.tuberculosis_H37Rv DVCLAVPPNLIGFVETAGLSAVAYGSRDSQEQLDEQ------FLHNAWK-
MAV_3258|M.avium_104 DVRLAVPPELVGFVESTGLAAVPYGP-NVQEFLDEE------FLRNMWRD
MAB_4112c|M.abscessus_ATCC_199 EVRMAVPPDLIGFAGSVGLSAVPYGI-HVGPQLDEYRDLWTSWTRHFWR-
MSMEG_0385|M.smegmatis_MC2_155 DVCIAVPPDLVRFAEDAGLSATSYGM-EVEPQLDAYRDIWTSWARKLWR-
TH_1989|M.thermoresistible__bu --------------------------------------------------
Mflv_0466|M.gilvum_PYR-GCK DIHVRTLAAGLQICRDEGFTAAAVDPRIEAIQADDT----------LTG-
Mvan_1905|M.vanbaalenii_PYR-1 TVHLRTLSSGLDHARGLGVSVEPIDPRIEAIELDDW----------KASN
MMAR_2353|M.marinum_M -PQTSIKLVREGISDLRQAWSDMAGTLKTLADGADLVLTGMIHQGIALNA
MUL_1529|M.ulcerans_Agy99 -PQTSIKLVREGISDLRQAWSDMAGTLKTLADGADLVLTGMIHQGIALNA
MLBr_02348|M.leprae_Br4923 -ILPPIKALQQ----LRQAWADMATDLKSLADGADLVMTGVVYQGVVANV
Mb1551|M.bovis_AF2122/97 -LQNPIKLLREAMAPVTEGWAELSAMLTPVAAGADLLLTGQIYQEVVANV
Rv1524|M.tuberculosis_H37Rv -LQNPIKLLREAMAPVTEGWAELSAMLTPVAAGADLLLTGQIYQEVVANV
MAV_3258|M.avium_104 FFRNPIRLVLKVWDPIIKYWAEASATLKSVAEGADLLSTGLNFEQAAANV
MAB_4112c|M.abscessus_ATCC_199 -LQDLVALCRQALKLVTEQWSEMSETLVSVAEGADLLSTSVGYEEPAANV
MSMEG_0385|M.smegmatis_MC2_155 -LQDFVNLCREALGVTISQWEDIGKTLVTLADGADLLTTGVGFEQPAANV
TH_1989|M.thermoresistible__bu --------------------------------------------------
Mflv_0466|M.gilvum_PYR-GCK TVRAAADTVEVLTARAPLEVADLLSAVESVQP--DVVIVDANCWGAMS-V
Mvan_1905|M.vanbaalenii_PYR-1 PVGALKLSIGAFGRRASYEIADLGKALTTVQP--DGVLVDVNCWGAHS-A
MMAR_2353|M.marinum_M AEYYGIPLATMH-FLPSRVNSRVIP--ILSPRLNRSVISALWWVHWRVTK
MUL_1529|M.ulcerans_Agy99 AEYYGIPLATMH-FLPSRVNSRVIP--ILSPRLNRSVISALWWVHWRVTK
MLBr_02348|M.leprae_Br4923 AEYYGIPFGVLH-FVPARVNGKIIP--SLPSPLNRAILATVWRAHWLLAK
Mb1551|M.bovis_AF2122/97 AEHHGIPLAALH-FYPVRANGEIAFPARLPAPLVRSTITAIDWLYWRMTK
Rv1524|M.tuberculosis_H37Rv AEHHGIPLAALH-FYPVRANGEIAFPARLPAPLVRSTITAIDWLYWRMTK
MAV_3258|M.avium_104 AEYYDIPLASLH-HFPMRANGQLVP--NMPSPLVRSTMTAIEWLFWRSTK
MAB_4112c|M.abscessus_ATCC_199 AEFYGIPLVALH-TMPWRPNGQLFP--VLPPMLTRTGMTAYDWLTWRVTK
MSMEG_0385|M.smegmatis_MC2_155 AEYYGIPLIALH-TFPWRPNGRLVP--AIPPLLTRSAMNVYDWLGWRLTK
TH_1989|M.thermoresistible__bu --------------------------------------------------
Mflv_0466|M.gilvum_PYR-GCK AETLGRPWVVLSPFTPYLRSPGAPPFGPGATPWPGPLGRIRDWGIGLVTT
Mvan_1905|M.vanbaalenii_PYR-1 VEATGVPWASFAPYTPALTVAGVPPFGLGLKPMSGPVGRLRDSVVRAGVS
MMAR_2353|M.marinum_M NPEEAQRRELGMAKASSSSTSRILKGRSLEIQAYDELCFPGLAAEWAEWG
MUL_1529|M.ulcerans_Agy99 NPEEAQRRELGMAKASSSSTSRILKGRSLEIQAYDELCFPGLAAEWAEWG
MLBr_02348|M.leprae_Br4923 KPEDAQRRELGLPKATSLSTRRIVKRGALEIQAYDELCFPGLAAEWAEYG
Mb1551|M.bovis_AF2122/97 GVEDAQRRELGLPKASTPAPRRMAVRGSLEIQAYDALCFPGLAAEW---G
Rv1524|M.tuberculosis_H37Rv GVEDAQRRELGLPKASTPAPRRMAVRGSLEIQAYDALCFPGLAAEW---G
MAV_3258|M.avium_104 KVDNAQRRQLGLPKATRRSQRRIAERGWLEIQAYDEVCFPGLAAEWAHWG
MAB_4112c|M.abscessus_ATCC_199 GAEDAQRRHLGLPQATSPSPQRIGQRNSLEIQAYDAVCFRGLAEEWAKYG
MSMEG_0385|M.smegmatis_MC2_155 QAEDAQRRELGLPMATSAARQRMAERGVLEIQAYDAISFPGLADEWARYG
TH_1989|M.thermoresistible__bu --------------------------------------------------
Mflv_0466|M.gilvum_PYR-GCK AVFDRPFARQIAPLRRALGLTPVRTAGDLLLRAPAVLVATGKPLEYP-HT
Mvan_1905|M.vanbaalenii_PYR-1 WPLERPAVAAINTVRSRVGLTPVGSLDQFLRRAPLLFLATGTPFQY--AA
MMAR_2353|M.marinum_M DRRPFVGALTLEMPTESDNEVLSWIASGTPPIYFGFGSMPVESPAATIAM
MUL_1529|M.ulcerans_Agy99 DRRPFVGALTLEMPTESDNEVLSWIASGTPPIYFGFGSMPVESPAATIAI
MLBr_02348|M.leprae_Br4923 DRRPFVGALTLELPTAADNEVLSWIAAGTPPIYFGFGSMPIVSPTDTVAM
Mb1551|M.bovis_AF2122/97 GRRPFVGALTMESATDADDEVASWIAADTPPIYFGFGSMPIGSLADRVAM
Rv1524|M.tuberculosis_H37Rv GRRPFVGALTMESATDADDEVASWIAADTPPIYFGFGSMPIGSLADRVAM
MAV_3258|M.avium_104 DRRPFVGALTMELPTESDDDVASWIAAGTPPICFGSGSIPLESPTATVEM
MAB_4112c|M.abscessus_ATCC_199 GRRPFVGALTMELTTSADDEVMSWIASGPPPICFASGSIPVESPAETVEM
MSMEG_0385|M.smegmatis_MC2_155 ARRPFVGTLTMELATADDSEVTSWIAHGTPPICFGFGSIPVESPAETIDM
TH_1989|M.thermoresistible__bu -------------------------------------------------M
Mflv_0466|M.gilvum_PYR-GCK DWGETVTMIGPAVFEPRAAQRPSWLDHIDDPIVLVTTSSVGQSDAALVET
Mvan_1905|M.vanbaalenii_PYR-1 DWGENVHMIGPCAPEKAHGDAPDWLTAIDRPIVLVTTSSERQGDAGLVSA
MMAR_2353|M.marinum_M ISAACAELGERALICTGSNDLGGLQAPENVKLVSGVSHAAVFPACRAVVH
MUL_1529|M.ulcerans_Agy99 ISAACAELGERALICTGSNDLGGLQAPENVKLVSGVSHAAVFPACCAVVH
MLBr_02348|M.leprae_Br4923 IAAACADLGERALISVKPKDLTQVPKFDHVKIVTSVSHAAVFPACRAVVH
Mb1551|M.bovis_AF2122/97 ISAACAELGERALICSGPSDATGIPQFDHVKVVRVVSHAAVFPTCRAVVH
Rv1524|M.tuberculosis_H37Rv ISAACAELGERALICSGPSDATGIPQFDHVKVVRVVSHAAVFPTCRAVVH
MAV_3258|M.avium_104 IGAASARLGERALICFGGTDVRGVPRFDHVKVVGPVNYASVFPACRAVVH
MAB_4112c|M.abscessus_ATCC_199 IGSACAELGERALVCAGATDFSGVQTSPHVKLVGVVNYAAVFPVSRAIVH
MSMEG_0385|M.smegmatis_MC2_155 IASACAELGERALVCAGGTDFGDSPRFEHVKVAGTVNYATVFPVCRAVVH
TH_1989|M.thermoresistible__bu FASVCSRLGERALICAGGTDIDGVPEYGHVKVVGAVNYARVFPACRAIVH
Mflv_0466|M.gilvum_PYR-GCK AVEALRDE-PVHLVVTAPTGDVDVMTRPGVTQVRFAPHSMLLEHAVCVIT
Mvan_1905|M.vanbaalenii_PYR-1 AVDALTDE-PVHVVATLPAGVDQVPGSAHATILRFVDHDLVLGRAVCAVT
. :: . .. . : :: . . :
MMAR_2353|M.marinum_M HGGAGTTAAGMRAGIPTLILWIWIEQPIWLAQIKRLKIGSGRRLASTTKE
MUL_1529|M.ulcerans_Agy99 HGGAGTTAAGMRAGIPTLILWIWIEQPIWLAQIKRLKIGSGRRLASTTKE
MLBr_02348|M.leprae_Br4923 HGGAGTTAASLRAGVPTLILWIFIEQPVWAAQIKRLKVGAGRRFSATTQR
Mb1551|M.bovis_AF2122/97 HGGAGTTAAGLRAGIPTLILWVTSDQPIWAAQIKQLKVGRGRRFSSATKE
Rv1524|M.tuberculosis_H37Rv HGGAGTTAAGLRAGIPTLILWVTSDQPIWAAQIKQLKVGRGRRFSSATKE
MAV_3258|M.avium_104 HGGSGTTAASLRAGIPTLALWSSADQPYWAAQIKRLKVGTARRFSATTSE
MAB_4112c|M.abscessus_ATCC_199 HGGSGTTAASLRAGVPTLILWTVGDQPFWGNQLRRMGVGASRRFSTTTRD
MSMEG_0385|M.smegmatis_MC2_155 HGGSGTTAASLRAGVPTLTLWTAGDQPFWGAQLKKLKVGASRRFSATTRD
TH_1989|M.thermoresistible__bu HGGSGTTAAVLRAGVPSLVTWSSADQPYWGNQVKRLKVGTSRRFSHTTPD
Mflv_0466|M.gilvum_PYR-GCK HGGMGVTQKALARGVPVCVVPFGRDQFEVARRVELAGCGTRLPAGKLSVG
Mvan_1905|M.vanbaalenii_PYR-1 HGGMGATQRALARGVPVCVVPYGRDQFEVARRAEVARCGTRLPAKRLSAP
*** *.* : *:* :* : . * :
MMAR_2353|M.marinum_M TLVSDLRCILGPDYVARARTIANEMSKPGESATRAADLLENEVSVS----
MUL_1529|M.ulcerans_Agy99 TLVSDLRCILGPDYVARP---------PG--LRRC---------------
MLBr_02348|M.leprae_Br4923 SLAADLRTILAPQYATRAREVANRMSKPDESVNAAADLLEDKASRNKSRT
Mb1551|M.bovis_AF2122/97 SLIADLRTILAPDYVTRAREIASRMTKPAASVTATADLLEDAARRAR---
Rv1524|M.tuberculosis_H37Rv SLIADLRTILAPDYVTRAREIASRMTKPAASVTATADLLEDAARRAR---
MAV_3258|M.avium_104 TLAADLRTILAPDYATRARDLAARMTKPAESIETTADLLEEAARRKTLG-
MAB_4112c|M.abscessus_ATCC_199 SLVSDLRTILTPECAARARAIAPHMSKPHDSVSKAADLLEAKASHP----
MSMEG_0385|M.smegmatis_MC2_155 TLVSDLRRILSPEYAVKAREVATRMTNPAESVSRAADLIEQNLDPTRRS-
TH_1989|M.thermoresistible__bu TLVADLRRILTPDYAVRARAVAARMTDPADSVVRAADLFETAVECAPGVA
Mflv_0466|M.gilvum_PYR-GCK RLRTAVKTAAT--MTGGAARVAAGFAATG-GVARGADVVESRLVARCALP
Mvan_1905|M.vanbaalenii_PYR-1 RLRNKIREAMG--LTSGARAVADGFAATG-GVARGADLFEHLVGGN----
* :: . . .
MMAR_2353|M.marinum_M -----
MUL_1529|M.ulcerans_Agy99 -----
MLBr_02348|M.leprae_Br4923 RYQDC
Mb1551|M.bovis_AF2122/97 -----
Rv1524|M.tuberculosis_H37Rv -----
MAV_3258|M.avium_104 -----
MAB_4112c|M.abscessus_ATCC_199 -----
MSMEG_0385|M.smegmatis_MC2_155 -----
TH_1989|M.thermoresistible__bu HRE--
Mflv_0466|M.gilvum_PYR-GCK EEQ--
Mvan_1905|M.vanbaalenii_PYR-1 -----