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VLTRPVIVLFSFSCGLAVATIYFSQPLLDTIGSQFSMPTAQVGIVLTLTQIGYAIGLLLIVPLGDIVDQR RLIVGQTVLLGVALLATAISPNAWTFLLSITTLGALAVVTQVMVTYTAVHAARERQGWAVGVVTGGIISG ILLARTVSGALSDLLGWRSVYAVAAIAVAAIATILARTLVGSDPTRHGPPYGRLLLSTLRLLRDESVLRS RAIIAMLVFAAITVLLTPMVLPLTSAPYHLSHTQVGLFGLAGAAGAVGAFKAGTWCDRGWANRVTGAGLS LMLAAWALAATLHWTLLGLAVAVVIIDFGLQSVHVANQSLIYRLDPELHGRVTAAYMTFYSIGSAIGAIA STWVYAARAWSGVCLLGAAISLGALAYWAALQRAAHQHRLRHQTHAEGLQDPVTHGTGECQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4064 | - | - | 100% (411) | major facilitator transporter |
| M. abscessus ATCC 19977 | MAB_0022c | - | 1e-75 | 40.41% (386) | permease |
| M. abscessus ATCC 19977 | MAB_2983c | - | 5e-16 | 27.65% (358) | chloramphenicol resistance protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1282 | - | 1e-05 | 27.67% (159) | drug-transport integral membrane protein |
| M. gilvum PYR-GCK | Mflv_5163 | - | 1e-09 | 25.44% (397) | protein of unknown function DUF894, DitE |
| M. tuberculosis H37Rv | Rv1250 | - | 2e-05 | 27.67% (159) | drug-transport integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0577 | - | 7e-10 | 23.22% (379) | integral membrane transport protein |
| M. avium 104 | MAV_1539 | - | 3e-12 | 21.04% (366) | major facilitator family protein transporter |
| M. smegmatis MC2 155 | MSMEG_2810 | - | 3e-66 | 37.04% (378) | major facilitator superfamily protein |
| M. thermoresistible (build 8) | TH_1317 | - | 2e-08 | 24.14% (406) | transmembrane transport protein |
| M. ulcerans Agy99 | MUL_3155 | - | 4e-08 | 24.70% (413) | hypothetical protein MUL_3155 |
| M. vanbaalenii PYR-1 | Mvan_1167 | - | 2e-09 | 26.79% (377) | protein of unknown function DUF894, DitE |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1282|M.bovis_AF2122/97 ----MTTAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIM
Rv1250|M.tuberculosis_H37Rv ----MTTAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIM
MAB_4064|M.abscessus_ATCC_1997 ----------------MLTRPVIVLFSFSCGLAVATIYFSQPLLD--TIG
MSMEG_2810|M.smegmatis_MC2_155 -------MTAEDLQHRGMSTRLTVLFALAGAMAVGNLYYTQPLLH--VIG
Mflv_5163|M.gilvum_PYR-GCK -------MTSPVSTSTWAPLQSPVFRALWIAQFVSNLGTWMQTVGAQWML
Mvan_1167|M.vanbaalenii_PYR-1 -------MALAGSTSTWAPLGSPIFRALWIAQFVSNLGTWMQTVGAQWML
TH_1317|M.thermoresistible__bu ---------------------------LWIAQFVSNLGTWMQTVGAQWML
MAV_1539|M.avium_104 ----MVMPNGPVAHQAGTRGYRRMTAALCGAGLASFAAMYCTQALLPALS
MMAR_0577|M.marinum_M -----MPESVTAPPELGIRHATPGLLALTIATCLAITTEILPVGLLPAIG
MUL_3155|M.ulcerans_Agy99 MTTNGRAIRGGLADAVGGPARMRVIVLLALVVGLEGASNGTIGALAVVLK
: :
Mb1282|M.bovis_AF2122/97 AQLRIGYATVVWVTSAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTV
Rv1250|M.tuberculosis_H37Rv AQLRIGYATVVWVTSAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTV
MAB_4064|M.abscessus_ATCC_1997 SQFSMPTAQVGIVLTLTQIGYAIGLLLIVPLGDIVDQRRLIVGQTVLLGV
MSMEG_2810|M.smegmatis_MC2_155 VSLHTEVGHVGLLVTATQIGYSLGVLLLVPLGDSRDRRRLIPTLMLLSAA
Mflv_5163|M.gilvum_PYR-GCK VDDPAAAVLVPLVQTATTLPVMLLALPSGVLADLVDRRRLLIATQGAMAA
Mvan_1167|M.vanbaalenii_PYR-1 VDDPRAAVLVPLVQTATTLPVMLLALPSGVLADLIDRRRLLIATQGAMAA
TH_1317|M.thermoresistible__bu VSTPAAEVLVPLVQTATTLPIMLLSLPSGVVADLVDRRRLLLATQSMMAA
MAV_1539|M.avium_104 AHHRIGPATAALTVSLTTGALALSIIPASVLSERYGRTRVMLISGVASSV
MMAR_0577|M.marinum_M HTFGVRDAVTGLLVSLYAVLVALLAVPLTVVTARFPRKPLLLTTLLGYAV
MUL_3155|M.ulcerans_Agy99 QAFGITNLQVGLLVTASTAIGIVVMLVSGTLADRVNRTRVLWITVLIWSV
. : : : : : .
Mb1282|M.bovis_AF2122/97 ASLGCGLSSGAGMLIAARVVQGVGAG----LLTPQTLSTITRIFPAHR-R
Rv1250|M.tuberculosis_H37Rv ASLGCGLSSGAGMLIAARVVQGVGAG----LLTPQTLSTITRIFPAHR-R
MAB_4064|M.abscessus_ATCC_1997 ALLATAISPNAWTFLLS--ITTLGAL----AVVTQVMVTYTAVHAARERQ
MSMEG_2810|M.smegmatis_MC2_155 ALTWCAVAPTLSALAVA--SLALGLT----TVSGQLLTPLAGDLADDRSR
Mflv_5163|M.gilvum_PYR-GCK GVGLLATLTGAGLTTPTVLLTLLFVIGCGQALTAPAWQAIQPDLVPSDQI
Mvan_1167|M.vanbaalenii_PYR-1 GVGLLAVLTGAGLTTPTVLLMLLFVIGCGQALTAPAWQAIQPDLVPAHQI
TH_1317|M.thermoresistible__bu AVAILAALTAAQLTTPTVLLILLFLIGCGQAFTAPAWQAIQPELVPREQI
MAV_1539|M.avium_104 IGLLLPFSPSLGVLVFGRAVQGVALAG-----IPAVAMALLAEEVDASSL
MMAR_0577|M.marinum_M SNTLVAIAPTFAMVAAGRAVGGVTHA-----LFFSLCIGYAPRLVGLADV
MUL_3155|M.ulcerans_Agy99 AMALGGISAGYGWLLASRVALGAVVA-----VGGPVVASLMGDFFAQHER
.
Mb1282|M.bovis_AF2122/97 GVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVN-VPVGVIGLILA
Rv1250|M.tuberculosis_H37Rv GVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVN-VPVGVIGLILA
MAB_4064|M.abscessus_ATCC_1997 GWAVGVVTGGIISGILLARTVSGALSDLLGWRSVYAVAAIAVAAIATILA
MSMEG_2810|M.smegmatis_MC2_155 GRVVGIVVSGLVTGILVSRIAGGVIAGAWGWRAVFAIAAAITAALALVLA
Mflv_5163|M.gilvum_PYR-GCK PAAAALGSMSMNGARAIGPAIAGALVSLTGPTIVFALNAVSFVGIVLVLM
Mvan_1167|M.vanbaalenii_PYR-1 PAAAALGSMSMNGARAIGPAIAGALVSLTGPTLVFALNAVSFIGIVLVLI
TH_1317|M.thermoresistible__bu PAAAALTSMSLNAARAVGPAVAGVLVAISGPTLVFTLNAVSFAGIVVVLL
MAV_1539|M.avium_104 GSAMGRYIAGTTIGGLAGRIVPSVVVQVGTWRVALLACSLITLAGTAVFA
MMAR_0577|M.marinum_M GRALALVGGGVSAGIVVGVPLLTSVGTAVGWRGAFAVLAVLAAVLLLVVA
MUL_3155|M.ulcerans_Agy99 GRIYGFVLAGEGICTALGVLVSGWLAAIT-WRLSFLWLAVTGLLLTLALA
. . : .
Mb1282|M.bovis_AF2122/97 AYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIV
Rv1250|M.tuberculosis_H37Rv AYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIV
MAB_4064|M.abscessus_ATCC_1997 RTLVGSDPTRHG--------PPYGRLLLSTLRLLRDESVLRS----RAII
MSMEG_2810|M.smegmatis_MC2_155 AAVPRVPPTTR---------VAYPKLLGSVLALAVREPTVRV----TLVL
Mflv_5163|M.gilvum_PYR-GCK WWRRPPVRSDYPP-------ERALAALSAGGRYIRSSPIVRR----ILLR
Mvan_1167|M.vanbaalenii_PYR-1 SWRRPAVQRDFPP-------ERALAALSAGGRYIRSSPIVRR----ILLR
TH_1317|M.thermoresistible__bu LWKRSSAEQTLAA-------ERPLAALQAGHRYVRSSPVVRR----ILFR
MAV_1539|M.avium_104 VLVPRSRFFTPKP--------ASVRAALRNLAGHLRNPVLAK----LFAV
MMAR_0577|M.marinum_M KLLPPVSSESAPP------------PAGTAKGRRRLAAVVSS--------
MUL_3155|M.ulcerans_Agy99 RTVPEPARGGDTFG-----ASAGSDRRDCSNDTLAAAVIAQRVSAHPHLI
Mb1282|M.bovis_AF2122/97 GGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLGIAIIAFAGTGMM
Rv1250|M.tuberculosis_H37Rv GGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMM
MAB_4064|M.abscessus_ATCC_1997 AMLVFAAITVLLTP--------MVLPLTSAPYHLSHTQVGLFGLAG----
MSMEG_2810|M.smegmatis_MC2_155 GALGFAMFTMFWTA--------LTFLLSGAPYDFTAWQIGLVGVAG----
Mflv_5163|M.gilvum_PYR-GCK TVLFIAPGSAVWGLLPVIARDQLGLGSAGYGALLGALGVGAVLGAFALSR
Mvan_1167|M.vanbaalenii_PYR-1 TVLFIAPASALWGLLPVIAANQLGLGSAGYGLLLGALGAGAVLGAFVLSG
TH_1317|M.thermoresistible__bu AALFILPASALWGLLPVVASSGLGLSSSGYGLMLGALGAGAVLGALTLSA
MAV_1539|M.avium_104 GFVLMGGFVTVYNY--------LGYRLAARPFGLAPSVVGLLFLLY----
MMAR_0577|M.marinum_M NALTYTGQFTLYTF----------ISAVLLAAGARPAFIGPLLLMCG---
MUL_3155|M.ulcerans_Agy99 LQESPEGRSLRWAVG-------YVLKIRTNVALMVASSFGYFFYTG----
. .
Mb1282|M.bovis_AF2122/97 LPVTFYAQAVCGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLG
Rv1250|M.tuberculosis_H37Rv LPVTFYAQAVCGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLG
MAB_4064|M.abscessus_ATCC_1997 --------------------------AAGAVGAFKAGTWCDR-------G
MSMEG_2810|M.smegmatis_MC2_155 --------------------------LVGALAAQGAGRLHDR-------G
Mflv_5163|M.gilvum_PYR-GCK LRARFGQNKLLIAGAAGFGMATAVLALVHNVALVAAALVVGG----AAWL
Mvan_1167|M.vanbaalenii_PYR-1 LRTRFGQNVLLTAGAAGFAVATAVLALVPDFAAVLAALVVGG----GAWL
TH_1317|M.thermoresistible__bu WQSAFRQNTLLALAAVGFAAATAVAVLVPDVVVVLIGLTVGG----MSWL
MAV_1539|M.avium_104 --------------------------LVGTGTSVVAGRLADR--------
MMAR_0577|M.marinum_M --------------------------VCSLAGLWYVGATLDR--------
MUL_3155|M.ulcerans_Agy99 ------------------------------LGTFAVALLRSR-------F
. .
Mb1282|M.bovis_AF2122/97 FGFSVLAIAMTWLLCEMAPGTPIWR-LVLPFIALGVAGAFVWSPLTVTAT
Rv1250|M.tuberculosis_H37Rv FGFSVLAIAMTWLLCEMAPGTPIWR-LVLPFIALGVAGAFVWSPLTVTAT
MAB_4064|M.abscessus_ATCC_1997 WANRVTGAGLSLMLAAWALAATLHW-TLLGLAVAVVIIDFGLQSVHVANQ
MSMEG_2810|M.smegmatis_MC2_155 RNVAATGACWCLGLAAWAVAAVSHN-LLIGIIVAAIVLDVSVQGLNILNQ
Mflv_5163|M.gilvum_PYR-GCK LTLSTLNASMQLSLPSWVRARGLSV-YQLIFMGGQAVGSLLWGLLAGGTS
Mvan_1167|M.vanbaalenii_PYR-1 LSLSTLNASMQLSLPAWVRARGLSV-YQLIFMGGQAIGSLLWGLLAGATN
TH_1317|M.thermoresistible__bu LALATLNASMQLSLPAWVRARGLSV-YLLIFMGGQALGSTMWGLVAGSTS
MAV_1539|M.avium_104 -RGRPLVLGAALPIAVAGLLLTVPP-SLAAIVAGVGVFTGGFFAAHTVAS
MMAR_0577|M.marinum_M NPRQTTVIIIVVVIGALLGLGASFP-ALLPVVLAAAVWNGAFGGIPSIYQ
MUL_3155|M.ulcerans_Agy99 RISQTLAISLIAIIGVGAPIGTLCAGRLADWLIGRGYLGARLGVAGAAFL
:
Mb1282|M.bovis_AF2122/97 RNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPGGVDALT
Rv1250|M.tuberculosis_H37Rv RNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPGGVDALT
MAB_4064|M.abscessus_ATCC_1997 ---------------SLIYRLDPELHGRVTAAYMTFYSIGSAIG------
MSMEG_2810|M.smegmatis_MC2_155 ---------------SRVFVVAQEARSRVNTAYVTANFVGGTGG------
Mflv_5163|M.gilvum_PYR-GCK ---------------SVISLLVSAGLLIFCGLSLWWWPLHAGTGNLDLTP
Mvan_1167|M.vanbaalenii_PYR-1 ---------------SVTSLLVSAGLLVVCALSSLWWPLHAGTGNLDLTP
TH_1317|M.thermoresistible__bu ---------------TVVAMLISAGLLVVSGLSAWWWPLHPQTGQLDVSP
MAV_1539|M.avium_104 ---------------GWVGAVAQRDRAEASALYLFSYYLGGSVAG-----
MMAR_0577|M.marinum_M ----------------AGAVRAQAATPEMAGAWVNATANLGIAAG-----
MUL_3155|M.ulcerans_Agy99 VAGG----------FFVPALLTDNVVIAVVAAFLAAIGLGGVNPP-----
Mb1282|M.bovis_AF2122/97 GPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTG
Rv1250|M.tuberculosis_H37Rv GPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTG
MAB_4064|M.abscessus_ATCC_1997 --AIASTWVYAARAWSGVCLLGAAISLGALAYWAALQRAAHQHRLRHQTH
MSMEG_2810|M.smegmatis_MC2_155 --SLAAAVLWSVGGWSAITVAGAAMSVLGCAVWAAARRGALRASRDVHTS
Mflv_5163|M.gilvum_PYR-GCK SSHWPEPTLLFEPEPLDGPVLVITAYRVLPENEEPFMSAMARLGRSRQRT
Mvan_1167|M.vanbaalenii_PYR-1 SSHWPEPTLVFEPEPLDGPVLVLTSYCVPAHNEGAFLAAMAVLGRSRQRT
TH_1317|M.thermoresistible__bu SAHWPEPALVFEPEPRDGPVLVLSTYRVAPEDEPAFLVAMQRQARSRQRT
MAV_1539|M.avium_104 ---AFGGVLYGVGGWSATVCFVVVLLMAGAALVALLVRDNGFRIGRRVVA
MMAR_0577|M.marinum_M --AAIGAGLLPTIGLAGLPWVAAALIAISLAVTLATGRGPTH--------
MUL_3155|M.ulcerans_Agy99 -LDAARLDIMHSRLWGRAEAIRTTLRSGFTAAAPLVFAWYPCSWRRSGAR
:
Mb1282|M.bovis_AF2122/97 AAVAKEPLPESDGDADDDDYVEYILRREPEEDCDTQPLRASRPAAAAASR
Rv1250|M.tuberculosis_H37Rv AAVAKEPLPESDGDADDDDYVEYILRREPEEDCDTQPLRASRPAAAAASR
MAB_4064|M.abscessus_ATCC_1997 AEGLQDPVTHGTGECQ----------------------------------
MSMEG_2810|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5163|M.gilvum_PYR-GCK GASMWQLFRSIEQESTFVETFIVRSWGEHMHQHYTRLTGQDQLIEQDVER
Mvan_1167|M.vanbaalenii_PYR-1 GASQWRLFRSVEQESTFVETFIVRSWGEHMHQHYTRLTGQDQLIEQNVEQ
TH_1317|M.thermoresistible__bu GAALWRLYRHLEREHTFVEAFLVRSWDEHLRQHHVRLTLVDQRVEEEVRR
MAV_1539|M.avium_104 GVASVK--------------------------------------------
MMAR_0577|M.marinum_M --------------------------------------------------
MUL_3155|M.ulcerans_Agy99 PVGWQPHRPG----------------------------------------
Mb1282|M.bovis_AF2122/97 SGAGGPLAVSWSTSAQGMPPGPPGRRAWQADTESTAPSAL
Rv1250|M.tuberculosis_H37Rv SGAGGPLAVSWSTSAQGMPPGPPGRRAWQADTESTAPSAL
MAB_4064|M.abscessus_ATCC_1997 ----------------------------------------
MSMEG_2810|M.smegmatis_MC2_155 ----------------------------------------
Mflv_5163|M.gilvum_PYR-GCK YTEGEAVAEHYLAVRDAR----------------------
Mvan_1167|M.vanbaalenii_PYR-1 YTDGTPVSQHYLAVRDV-----------------------
TH_1317|M.thermoresistible__bu YAEGPPLVEHLIAVNFDEITRRGV----------------
MAV_1539|M.avium_104 ----------------------------------------
MMAR_0577|M.marinum_M ----------------------------------------
MUL_3155|M.ulcerans_Agy99 ----------------------------------------