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KNSAQGPASGSARTLPRSVVALLAIATATSVAVAYYSQPLLDAIGTDLGIPATVAPLIVTLTQLGFAASL FLILPLGDMLNRRRLIVGLSVLSALVLGLTALAPTGTWVLWLSPLVGAMAVVAQLLVALTATLAPAEQRG RVVGTVMSGLLIGILLARTAAGLIADLAGWRAVYVTAATSMLAVAAALARRLPSEESAGTTRNYIRLLGS VLDLVYQQKVLRTRMLFGAIAFAQFSVLWTALTSLLSGEPYGYSEGVIGLFGVIGAAGALGARFAGKLAD SGRSATTTLGAAITMLVSWPALLFGGDDLIALVLGILLLDFGVQAMHVTNQSQIYALPGDARSRITSAYM TAYFAGGALGSAAVSVAGSRWGWTGVCTVGAGFALLQLLTAALRPRESSQAIGALSVCSQDKNLWSLGES NS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0022c | - | - | 100% (423) | permease |
| M. abscessus ATCC 19977 | MAB_4064 | - | 1e-75 | 40.41% (386) | major facilitator transporter |
| M. abscessus ATCC 19977 | MAB_2706c | - | 7e-23 | 26.17% (386) | putative transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1908 | - | 8e-07 | 25.20% (254) | hypothetical protein Mb1908 |
| M. gilvum PYR-GCK | Mflv_1475 | - | 1e-10 | 27.66% (329) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv1877 | - | 8e-07 | 25.20% (254) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_3524 | - | 9e-13 | 25.64% (390) | hypothetical protein MMAR_3524 |
| M. avium 104 | MAV_1539 | - | 2e-23 | 27.09% (395) | major facilitator family protein transporter |
| M. smegmatis MC2 155 | MSMEG_2810 | - | 1e-72 | 41.60% (375) | major facilitator superfamily protein |
| M. thermoresistible (build 8) | TH_3988 | - | 3e-13 | 28.22% (287) | PUTATIVE putative MFS permease |
| M. ulcerans Agy99 | MUL_0949 | - | 3e-08 | 23.80% (437) | integral membrane transport protein |
| M. vanbaalenii PYR-1 | Mvan_1322 | - | 5e-13 | 22.95% (440) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_0022c|M.abscessus_ATCC_199 ---------MKNSAQGPASGSARTLPRSVVALLAIATATSVAVAYYSQPL
MSMEG_2810|M.smegmatis_MC2_155 --------------MTAEDLQHRGMSTRLTVLFALAGAMAVGNLYYTQPL
Mb1908|M.bovis_AF2122/97 MAGPTAPTTAPTAIRAGGPLLSPVRRNIIFTALVFGVLVAATGQTIVVPA
Rv1877|M.tuberculosis_H37Rv MAGPTAPTTAPTAIRAGGPLLSPVRRNIIFTALVFGVLVAATGQTIVVPA
MAV_1539|M.avium_104 ---------MVMPNGPVAHQAGTRGYRRMTAALCGAGLASFAAMYCTQAL
Mflv_1475|M.gilvum_PYR-GCK --------------------MAPLSPTAQRAPLLAAGFTTAFGAHAVAGT
Mvan_1322|M.vanbaalenii_PYR-1 --------------MTDTHRGDDGGTPLALAALLSGTLVGTISNNVVNVP
MMAR_3524|M.marinum_M -------------------MKASAPSRRIVAVLLCVVPLNQIPMDAYTPA
TH_3988|M.thermoresistible__bu MSESKASQDASAPAADPVDATARRTPWIAILAAALGIFVMITIEELPIGV
MUL_0949|M.ulcerans_Agy99 ----------------MSRVALACVVGSTVEYYDFCIYGTAAALVFPAVF
MAB_0022c|M.abscessus_ATCC_199 LDAIGTDLGIPATVAPLIVTLTQLGFAASLFLILPLGDMLNRRRLIVGLS
MSMEG_2810|M.smegmatis_MC2_155 LHVIGVSLHTEVGHVGLLVTATQIGYSLGVLLLVPLGDSRDRRRLIPTLM
Mb1908|M.bovis_AF2122/97 LPTIVAELGSTVDQS-WAVTSYLLGGTVVVVVAGKLGDLLGRNRVLLGSV
Rv1877|M.tuberculosis_H37Rv LPTIVAELGSTVDQS-WAVTSYLLGGTVVVVVAGKLGDLLGRNRVLLGSV
MAV_1539|M.avium_104 LPALSAHHRIGPATAALTVSLTTGALALSIIPASVLSERYGRTRVMLISG
Mflv_1475|M.gilvum_PYR-GCK LGTTTTGTAASLLTLGAMLAIYDGAEVILKPLFGTLADRIGARTVLIAGL
Mvan_1322|M.vanbaalenii_PYR-1 MPAILADFDAPLESGVFIVVGFLLTFTATMPVVGWIGDRIGRRRVYCASM
MMAR_3524|M.marinum_M LPQMETSIGTTATALQSTVTVFMIGMALSYLAVGIMSDSWGRKPVLMGCA
TH_3988|M.thermoresistible__bu LTLIGDDLGLSSGVVGLTVTIPGVLAGAVAVLTPTLIGRLDRRLALVSAL
MUL_0949|M.ulcerans_Agy99 YPGLSPALATIASMG--TFATAFLSRPLGAAVFGHFGDRLGRKKTLVATL
. : .
MAB_0022c|M.abscessus_ATCC_199 VLSALVLGLTALAPTGT--------WVLWLSPLVGAMA-VVAQLLVALTA
MSMEG_2810|M.smegmatis_MC2_155 LLSAAALTWCAVAPTLS--------ALAVASLALGLTT-VSGQLLTPLAG
Mb1908|M.bovis_AF2122/97 VVFVVGSVLCGLSQTMT--------MLAISRALQGVGAGAISVTAYALAA
Rv1877|M.tuberculosis_H37Rv VVFVVGSVLCGLSQTMT--------MLAISRALQGVGAGAISVTAYALAA
MAV_1539|M.avium_104 VASSVIGLLLPFSPSLG--------VLVFGRAVQGVALAGIPAVAMALLA
Mflv_1475|M.gilvum_PYR-GCK AVFAVASLSFAVADETA--------WLWAARLGQGIGAAAFSPAASALVA
Mvan_1322|M.vanbaalenii_PYR-1 IGTALCAIGAATAPTLE--------LLILWRCLGGLAASALGPAVMGLLT
MMAR_3524|M.marinum_M AALTVTSLACAAANNVA--------MLLVLRFLQGGACSAFIVVAIAIAA
TH_3988|M.thermoresistible__bu LLVFVSAATSAIAPNLP--------VLLASRLFAGMAIGVFWALLAVVVA
MUL_0949|M.ulcerans_Agy99 LIMALSTVTVGVVPSTATIGVSAPLILVALRLLQGFAVGGEWAGSALLSI
: * :
MAB_0022c|M.abscessus_ATCC_199 TLAPAEQRGRVVGTVMSGLLIGILLA--------RTAAGLIADLAGWRA-
MSMEG_2810|M.smegmatis_MC2_155 DLADDRSRGRVVGIVVSGLVTGILVS--------RIAGGVIAGAWGWRA-
Mb1908|M.bovis_AF2122/97 EVVPLRDRGRYQGVLGAVFGVNTVTG--------PLLGGWLTDYLSWRW-
Rv1877|M.tuberculosis_H37Rv EVVPLRDRGRYQGVLGAVFGVNTVTG--------PLLGGWLTDYLSWRW-
MAV_1539|M.avium_104 EEVDASSLGSAMGRYIAGTTIGGLAG--------RIVPSVVVQVGTWRV-
Mflv_1475|M.gilvum_PYR-GCK RLAPASGQGRAFGTYGSYKSVGYTLG--------PLIGGAIVTFGGLQA-
Mvan_1322|M.vanbaalenii_PYR-1 WLFAGERRGRAVGAWASVNGIGQAIG--------PTMGGFIADAWGWRW-
MMAR_3524|M.marinum_M DCFEGARLRSVNGLLGAAWSAAPILA--------PAVGGFIVEYASWRY-
TH_3988|M.thermoresistible__bu RVAHPDDLPKALTLAFGGVSVAVVLG--------VPFAAWIGAMVGWRW-
MUL_0949|M.ulcerans_Agy99 ESAPAHKRGYYGMFTVLGGGVALVVSGLTFLGVNYTIGESSSALLQWGWR
.
MAB_0022c|M.abscessus_ATCC_199 VYVTAATSMLAVAAALARRLPSEESAG-------TTRNYIRLLGSVLDLV
MSMEG_2810|M.smegmatis_MC2_155 VFAIAAAITAALALVLAAAVPRVPPT--------TRVAYPKLLGSVLALA
Mb1908|M.bovis_AF2122/97 AFWINVPVSIAVLTVAATAVPALARP---------PKPVIDYLG-ILVIA
Rv1877|M.tuberculosis_H37Rv AFWINVPVSIAVLTVAATAVPALARP---------PKPVIDYLG-ILVIA
MAV_1539|M.avium_104 ALLACSLITLAGTAVFAVLVPRSRFFT-------PKPASVRAALRNLAGH
Mflv_1475|M.gilvum_PYR-GCK LFAVMAALAAAVAVWAAVAVPRLAVLPR------TRQTLLDTVRRFSESS
Mvan_1322|M.vanbaalenii_PYR-1 VFVPLVPVALAGLIGTLRHIPRYPGTRMSFDAVGATALTVGSGLLILGVA
MMAR_3524|M.marinum_M VFVLIAALSVVVGLAVTWALPETLDQES------RTRFELGQTWQVLTAT
TH_3988|M.thermoresistible__bu AFVLVGALGLMVAVALTVLLPPVPVAER-------TTLGQLGAAWSIPAA
MUL_0949|M.ulcerans_Agy99 VPFLLSALLIAFALYVRLEINETPVFARAMAQADDQESTAAARAPLAAVL
:
MAB_0022c|M.abscessus_ATCC_199 YQQKVLRTRMLFGAIAFAQFSVLWTALTSLLSGEPYGYSEGVIG------
MSMEG_2810|M.smegmatis_MC2_155 VREPTVRVTLVLGALGFAMFTMFWTALTFLLSGAPYDFTAWQIG------
Mb1908|M.bovis_AF2122/97 VATTALIMATSWGGTTYAWGSATIVGL-LIGAAVALGFFVWLEGRARCGH
Rv1877|M.tuberculosis_H37Rv VATTALIMATSWGGTTYAWGSATIVGL-LIGAAVALGFFVWLEGRAAAAI
MAV_1539|M.avium_104 LRNPVLAKLFAVGFVLMGGFVTVYNYLGYRLAARPFGLAPSVVG------
Mflv_1475|M.gilvum_PYR-GCK FVTPTLALAAATAALSAGVGFLPVLGTDFGLSPVVTGAVVSVLA------
Mvan_1322|M.vanbaalenii_PYR-1 LIPRLGVSVAVLSAIAVAVVVLAFFVWHCLRTPEPFVDVRLVAESRFAR-
MMAR_3524|M.marinum_M ARNRVFLALAAIFGLLAGPQLSFGVAAPFLYQD-EMGFSPSAYG------
TH_3988|M.thermoresistible__bu RTGVLVTLVMVTAHFTAYTYASPVLQDRIHITESGVGPMLFVFG------
MUL_0949|M.ulcerans_Agy99 CRQRREIVLAAGAMLAAFGCLYLASTFLPSYAQLHLGYSRNLVL------
MAB_0022c|M.abscessus_ATCC_199 ----------------------------------LFGVIGAAGALG----
MSMEG_2810|M.smegmatis_MC2_155 ----------------------------------LVGVAGLVGALA----
Mb1908|M.bovis_AF2122/97 PAAQAVWQP--SICRVLR--------------PVLRGRIRDAGCTD----
Rv1877|M.tuberculosis_H37Rv LPPRLFGSPVFAVCCVLSFVVGFAMLGALTFVPIYLGYVDGASATASGLR
MAV_1539|M.avium_104 ----------------------------------LLFLLYLVGTGT----
Mflv_1475|M.gilvum_PYR-GCK ----------------------------------LTTAVVQPLAGR----
Mvan_1322|M.vanbaalenii_PYR-1 --------------------------------STLAAFAFMFGLGAT---
MMAR_3524|M.marinum_M ----------------------------------LIALVVGVAVLLG---
TH_3988|M.thermoresistible__bu ----------------------------------IAGFLGNFAAGP----
MUL_0949|M.ulcerans_Agy99 ----------------------------------LIGVLGGLVCIG----
MAB_0022c|M.abscessus_ATCC_199 -----------ARFAGKLADSGR----------SATTTLGAAITMLVSWP
MSMEG_2810|M.smegmatis_MC2_155 -----------AQGAGRLHDRGR----------NVAATGACWCLGLAAWA
Mb1908|M.bovis_AF2122/97 ---------LRTDLSGVRGRRVG-----DRVRSAHVADGDRPADRLDRDG
Rv1877|M.tuberculosis_H37Rv TLPMVIGLLIASTGTGVLVGRTGRYKIFPVAGMALMAVAFLLMSQMDEWT
MAV_1539|M.avium_104 -----------SVVAGRLADRRG----------RPLVLGAALPIAVAGLL
Mflv_1475|M.gilvum_PYR-GCK -----------AADSGRISLTSG--------------LFTGVVVTAAGVA
Mvan_1322|M.vanbaalenii_PYR-1 ----------LLAVPLYLVDRGR------------SGSVAGLVLLAVPAS
MMAR_3524|M.marinum_M -----------SFSTGMLATRMA-----------------FRRLAFADWT
TH_3988|M.thermoresistible__bu ----------------LLRRSMR-----------------------ATYV
MUL_0949|M.ulcerans_Agy99 ----------FVALSAILCDRFG--------RRRVMLVGWAVGLFWSPLV
MAB_0022c|M.abscessus_ATCC_199 ALLFG---------------------------GDDLIA------------
MSMEG_2810|M.smegmatis_MC2_155 VAAVS---------------------------HNLLIG------------
Mb1908|M.bovis_AF2122/97 CPGRP------------------------DGPLQDLPGRGDG--------
Rv1877|M.tuberculosis_H37Rv PPLLQSLYLVVLGAGIGLSMQVLVLIVQNTSSFEDLGVATSGVTFFRVVG
MAV_1539|M.avium_104 LTVPP-----------------------------SLAA------------
Mflv_1475|M.gilvum_PYR-GCK AAALP-----------------------------GLVG------------
Mvan_1322|M.vanbaalenii_PYR-1 MTVLG-----------------------------PLVGRYLDRIGPR---
MMAR_3524|M.marinum_M LYMVG---------------------------------------------
TH_3988|M.thermoresistible__bu VLPIG---------------------------------------------
MUL_0949|M.ulcerans_Agy99 MPLIG---------------------------------------------
MAB_0022c|M.abscessus_ATCC_199 -----LVLGILLLDFGVQAMHVTNQSQIYALPGDAR------------SR
MSMEG_2810|M.smegmatis_MC2_155 -----IIVAAIVLDVSVQGLNILNQSRVFVVAQEAR------------SR
Mb1908|M.bovis_AF2122/97 -----ADGGCVPADVADGRVD--ATAAAIAVPGRPR----------CRHR
Rv1877|M.tuberculosis_H37Rv ASFGTATFGALFVNFLDRRLGSALTSGAVPVPAVPSPAVLHQLPQSMAAP
MAV_1539|M.avium_104 -----IVAGVGVFTGGFFAAHTVASGWVGAVAQRDR------------AE
Mflv_1475|M.gilvum_PYR-GCK -----LLGGAVVIGVGCGLITPLAFTMLARSTPEER-----------LGQ
Mvan_1322|M.vanbaalenii_PYR-1 ---RVLRTGLLLMAAGQVGLAVAVGGRIADRVHGLAG----------LTA
MMAR_3524|M.marinum_M --AALLLGSAPVVGVNPWAITLAVSLAVAGCGALVP-----------QAQ
TH_3988|M.thermoresistible__bu -----VMVGVXXXGPNSRWRPDGTRM------------------------
MUL_0949|M.ulcerans_Agy99 ------SGDTVGFTVALLGLYAVAASGFGPAASLIP---------ELFAT
MAB_0022c|M.abscessus_ATCC_199 ITSAYMTAYFAG--------------------------------------
MSMEG_2810|M.smegmatis_MC2_155 VNTAYVTANFVG--------------------------------------
Mb1908|M.bovis_AF2122/97 IVHAGARSHR-------AEHVV--------------------------FR
Rv1877|M.tuberculosis_H37Rv IVRAYAESLTQVFLCAVSVTVVGFILALLLREVPLTDIHDDADDLGDGFG
MAV_1539|M.avium_104 ASALYLFSYYLG--------------------------------------
Mflv_1475|M.gilvum_PYR-GCK TMGAAEIG------------------------------------------
Mvan_1322|M.vanbaalenii_PYR-1 ILVVVGIGIAFVQTP-----------------------------------
MMAR_3524|M.marinum_M AAALGAFSRNLG--------------------------------------
TH_3988|M.thermoresistible__bu --------------------------------------------------
MUL_0949|M.ulcerans_Agy99 RYRYTGTALALN--------------------------------------
MAB_0022c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_2810|M.smegmatis_MC2_155 --------------------------------------------------
Mb1908|M.bovis_AF2122/97 RPRRRNIG-------CDLLPGGR----------------------RLVWY
Rv1877|M.tuberculosis_H37Rv VPRAESPEDVLEIAVRRMLPNGVRLRDIATQPGCGLGVAELWALLRIYQY
MAV_1539|M.avium_104 --------------------------------------------------
Mflv_1475|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1322|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_3524|M.marinum_M --------------------------------------------------
TH_3988|M.thermoresistible__bu --------------------------------------------------
MUL_0949|M.ulcerans_Agy99 --------------------------------------------------
MAB_0022c|M.abscessus_ATCC_199 ----------GALGSAAVSVAGSRWGWTGVCTVGAGFALLQLLTAALRPR
MSMEG_2810|M.smegmatis_MC2_155 ----------GTGGSLAAAVLWSVGGWSAITVAGAAMSVLGCAVWAAARR
Mb1908|M.bovis_AF2122/97 R------NIRCVVRKLPGPKTRFRADVGRRACPGSAISG--CLASAAPEH
Rv1877|M.tuberculosis_H37Rv QRLFEAVRLTDIGRHLHVPYQVFEPVFDRLVQTGYAARDGDILTLTPSGH
MAV_1539|M.avium_104 ----------GSVAGAFGGVLYGVGGWSATVCFVVVLLMAGAALVALLVR
Mflv_1475|M.gilvum_PYR-GCK ----------RECGDAAGPLVVAAIAAASTVPFGFLGLAAVVAASGVGVR
Mvan_1322|M.vanbaalenii_PYR-1 -------AATGATRSPAGAQGTGLGLYNLIRFSGSAMGAAWVAIALAAFG
MMAR_3524|M.marinum_M -------LVSGLFGTLTYLIIAAIMAIVGVSPERTQAPLGWLYVLCGALV
TH_3988|M.thermoresistible__bu --------------------------------------------------
MUL_0949|M.ulcerans_Agy99 --------VAGIVGGAAPPLIAGTLLASYGSSAVGLMMTALVAASLLCTY
MAB_0022c|M.abscessus_ATCC_199 ESSQAIGALSVCSQDKNLWSLGESNS------------------------
MSMEG_2810|M.smegmatis_MC2_155 ------GALRASRDVHTS--------------------------------
Mb1908|M.bovis_AF2122/97 GRPDRAGICR----VAHPGVPLRGLGHGGRFHPGAVAARGTAHRHPR---
Rv1877|M.tuberculosis_H37Rv RQVDSLAVLIRQWLLDHLAVAPGLKRQPDHQFEAALQHVTDAVLVQRDWY
MAV_1539|M.avium_104 DNGFRIGRRVVAGVASVK--------------------------------
Mflv_1475|M.gilvum_PYR-GCK RGRGRVGGVG----------------------------------------
Mvan_1322|M.vanbaalenii_PYR-1 AATGYSAVFLVVGGVAVLGLLGSFVGPDPAPAR-----------------
MMAR_3524|M.marinum_M FAALAWVTPRVQGEKPTPG-------------------------------
TH_3988|M.thermoresistible__bu --------------------------------------------------
MUL_0949|M.ulcerans_Agy99 LLPETAGAPLTAA-------------------------------------
MAB_0022c|M.abscessus_ATCC_199 ----------------
MSMEG_2810|M.smegmatis_MC2_155 ----------------
Mb1908|M.bovis_AF2122/97 ----------------
Rv1877|M.tuberculosis_H37Rv EDLGDLSESRQLAATT
MAV_1539|M.avium_104 ----------------
Mflv_1475|M.gilvum_PYR-GCK ----------------
Mvan_1322|M.vanbaalenii_PYR-1 ----------------
MMAR_3524|M.marinum_M ----------------
TH_3988|M.thermoresistible__bu ----------------
MUL_0949|M.ulcerans_Agy99 ----------------