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SPVAVPEHRVGKHWAVQKLGHFVDASGYARFVAAYRAGMARLPQIARSFDVPTRLGSVRAYRFGACGGVP LLLLTGRGGSTPLWRANLTSLLSRRSVYCIDLLGEPGMSVQDKPITGPQDHADWLEDVMAGLNLGAVHVV GLSIGGWAAVNHAIRYPCRVRSLVLLDPALTFAPLTWKMVLVSLGSVIPGTPQAIRNRLLSWSAGGAQVD ESLPEAALISAAARDFRICLPSPKVFSDKQLRRLSMPVLTVIAGRTIVHDARRAAQRARSAVPDNRVHVW PDASHALNGEFPGRISELTHEFLDTVEAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3742c | - | - | 100% (310) | hypothetical protein MAB_3742c |
| M. abscessus ATCC 19977 | MAB_3034 | - | 2e-08 | 33.63% (113) | hydrolase |
| M. abscessus ATCC 19977 | MAB_3517 | - | 2e-07 | 35.90% (117) | putative hydrolase, alpha/beta fold LipV |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2734 | - | 4e-12 | 24.37% (279) | hydrolase |
| M. gilvum PYR-GCK | Mflv_3952 | - | 5e-14 | 27.80% (277) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | Rv2715 | - | 4e-12 | 24.37% (279) | hydrolase |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_1997 | - | 7e-11 | 24.39% (287) | hydrolase |
| M. avium 104 | MAV_4567 | - | 9e-14 | 28.24% (262) | dihydrolipoyllysine-residue acetyltransferase component of |
| M. smegmatis MC2 155 | MSMEG_1570 | - | 8e-79 | 47.06% (306) | carboxylesterase |
| M. thermoresistible (build 8) | TH_1700 | - | 8e-83 | 50.00% (306) | carboxylesterase |
| M. ulcerans Agy99 | MUL_3358 | - | 5e-11 | 24.39% (287) | hydrolase |
| M. vanbaalenii PYR-1 | Mvan_2445 | - | 1e-11 | 26.71% (277) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3952|M.gilvum_PYR-GCK ---------------------------------MTARTPNLRPVRELT-P
Mvan_2445|M.vanbaalenii_PYR-1 ---------------------------------MTERKPNLRPVRELT-P
Mb2734|M.bovis_AF2122/97 ---------------------------------MTERKRNLRPVRDVAPP
Rv2715|M.tuberculosis_H37Rv ---------------------------------MTERKRNLRPVRDVAPP
MMAR_1997|M.marinum_M ---------------------------------MTERKRNLRPVREVTAP
MUL_3358|M.ulcerans_Agy99 ---------------------------------MTERKRNLRPVREVTAP
MAV_4567|M.avium_104 ---------------------------------MS---------------
MSMEG_1570|M.smegmatis_MC2_155 ---MEVAVPQVNIASRWSRGGLGAFVGETAFAHYLDAYRAGMALLPPHE-
TH_1700|M.thermoresistible__bu MTPTDLAVPDVRIG---PHRDIGHFRDAAAFDRFLEVYRRGMATLPTFE-
MAB_3742c|M.abscessus_ATCC_199 --MSPVAVPEHRVGKHWAVQKLGHFVDASGYARFVAAYRAGMARLPQIAR
Mflv_3952|M.gilvum_PYR-GCK TLRYCTIHGYRRAYRIAGS--GPAILLIHGIGDNSTTWAGVQTQLAQRFT
Mvan_2445|M.vanbaalenii_PYR-1 TLKFCTIHGYRRAFRVAGS--GPAILLIHGIGDNSTTWSTVQTQLAQRFT
Mb2734|M.bovis_AF2122/97 TLQFRTVHGYRRAFRIAGS--GPAILLIHGIGDNSTTWNGVHAKLAQRFT
Rv2715|M.tuberculosis_H37Rv TLQFRTVHGYRRAFRIAGS--GPAILLIHGIGDNSTTWNGVHAKLAQRFT
MMAR_1997|M.marinum_M SLQFRTIHGYKRAFRIAGS--GPAILLIHGIGDNSTTWTGIHAKLAQRFT
MUL_3358|M.ulcerans_Agy99 SLQFRTIHGYKRAFRIAGS--GPAILLIHGIGDNSTTWTGIHAKLAQRFT
MAV_4567|M.avium_104 ELKFLELHGDRVAFRDQGE--GEVLLLIHGMAGSSETWRSVIPPLAKKFR
MSMEG_1570|M.smegmatis_MC2_155 TFDVPTAFGTVRSYRFAGPECGAPVVLLPGRNAAAPMYATNLTALLRHRT
TH_1700|M.thermoresistible__bu VRDVTTAFGTVRAYRFDGP-AGPPVVLLPGRNAATPMYRGNLPTLLRQRT
MAB_3742c|M.abscessus_ATCC_199 SFDVPTRLGSVRAYRFGAC-GGVPLLLLTGRGGSTPLWRANLTSLLSRRS
* ::* . * ::*: * : : . * :
Mflv_3952|M.gilvum_PYR-GCK VIAPDLLG-HGKSDKPRADYSVAAYANGMRDLLSVLNIDSATVVGHSLGG
Mvan_2445|M.vanbaalenii_PYR-1 VIAPDLLG-HGRSDKPRADYSVAAYANGMRDLLSVLDIDDVTVIGHSLGG
Mb2734|M.bovis_AF2122/97 VIAPDLLG-HGQSDKPRADYSVAAYANGMRDLLSVLDIERVTIVGHSLGG
Rv2715|M.tuberculosis_H37Rv VIAPDLLG-HGQSDKPRADYSVAAYANGMRDLLSVLDIERVTIVGHSLGG
MMAR_1997|M.marinum_M VIAPDLLG-HGRSDKPRADYSIAAYANGMRDLLSVLDIERVTIIGHSLGG
MUL_3358|M.ulcerans_Agy99 VIAPDLLG-HGRSDKPRADYSIAAYANGMRDLLSVLDIERVTIIGHSLGG
MAV_4567|M.avium_104 VIAPDLLG-HGESAKPRTDYSLGAFAVWLRDFLDELGVSRATVVGHSLGG
MSMEG_1570|M.smegmatis_MC2_155 VYAVDLLGEAGLSVQHTPIRTVEDQARWLDDALGGLGLDRAHLFGVSVGG
TH_1700|M.thermoresistible__bu VYGIDLLGEAGLSVQHTPIRSADDIAHWLDDALAGLGLPHAHLLGVSIGG
MAB_3742c|M.abscessus_ATCC_199 VYCIDLLGEPGMSVQDKPITGPQDHADWLEDVMAGLNLGAVHVVGLSIGG
* **** * * : . * : * : *.: . :.* *:**
Mflv_3952|M.gilvum_PYR-GCK GVAMQFAYQFPQLVDRLILVGAGGVTKDVNIALRAASLPMGTEALALLRL
Mvan_2445|M.vanbaalenii_PYR-1 GVAMQFAYQFPQLVNRLILVGAGGVTKDVNIALRLASLPMGSEALALLRL
Mb2734|M.bovis_AF2122/97 GVAMQFAYQFPQLVDRLILVSAGGVTKDVNIVFRLASLPMGSEAMALLRL
Rv2715|M.tuberculosis_H37Rv GVAMQFAYQFPQLVDRLILVSAGGVTKDVNIVFRLASLPMGSEAMALLRL
MMAR_1997|M.marinum_M GVAMQFAYQFPQLVDRLILVGAGGVTKDVNVVFRLASLPMGAEALALLRL
MUL_3358|M.ulcerans_Agy99 GVAMQFAYQFPQLVDRLILVGAGGVTKDVNVVFRLASLPMGAEALALLRL
MAV_4567|M.avium_104 GVAMQFVYQHPDYAQRLILISSGGLGPDVGWVLRLLSAPG---AELVLPV
MSMEG_1570|M.smegmatis_MC2_155 WTAVNAAVHRPGRIASLTLLDP---------VFTFVRIPLAPIAASVLMF
TH_1700|M.thermoresistible__bu WTAMNLAVRRPQRVASLTLLDP---------VFTFAPVRTTPMLASIALI
MAB_3742c|M.abscessus_ATCC_199 WAAVNHAIRYPCRVRSLVLLDP---------ALTFAPLTWKMVLVSLGSV
.*:: . : * * *:.. .: : .
Mflv_3952|M.gilvum_PYR-GCK PLLLPTLRLLGRVGGPLLGNTRIGRDIPNMLRILADLPEPTASSAFARTL
Mvan_2445|M.vanbaalenii_PYR-1 PLVLPALQVLGRVSGTVFGSTGVGRDIPDMLRILADLPEPTASSAFARTL
Mb2734|M.bovis_AF2122/97 PLVLPAVQIAGRIVGKAIGTTSLGHDLPNVLRILDDLPEPTASAAFGRTL
Rv2715|M.tuberculosis_H37Rv PLVLPAVQIAGRIVGKAIGTTSLGHDLPNVLRILDDLPEPTASAAFGRTL
MMAR_1997|M.marinum_M PMVLPTVQLAGKVLGMALGSTALGQDLPNVLRILDDLPEPTASSAFTRTL
MUL_3358|M.ulcerans_Agy99 PMVLPTVQLAGKVLGMALGSTALGQDLPNVLRILDDLPEPTASSAFTRTL
MAV_4567|M.avium_104 IAPTPVLSVGNKLRSWLRGAGIQSPRGAELWNAYSSLSDGETRQSFLKTL
MSMEG_1570|M.smegmatis_MC2_155 APGVP-ERWRRRVQSWIAGGADLDAAAPEATLIGAGATDFTLRTPMPKLF
TH_1700|M.thermoresistible__bu APGVP-PALRRRVLRWISGGADIDAAADEAALIATASRNFVLRQPIPRSF
MAB_3742c|M.abscessus_ATCC_199 IPGTP-QAIRNRLLSWSAGGAQVDESLPEAALISAAARDFRICLPSPKVF
* :: * . : : . : :
Mflv_3952|M.gilvum_PYR-GCK RSVVDWRGQVVTMLDRCYLTQSVPVQLIWGSQDSVIPVSHAEMAHTAMPG
Mvan_2445|M.vanbaalenii_PYR-1 RAVVDWRGQVVTMLDRCYLTQSVPVQLIWGDCDAVIPVSHGEMAHAAMPG
Mb2734|M.bovis_AF2122/97 RAVVDWRGQMVTMLDRCYLTEAIPVQIIWGTKDVVLPVRHAHMAHAAMPG
Rv2715|M.tuberculosis_H37Rv RAVVDWRGQMVTMLDRCYLTEAIPVQIIWGTKDVVLPVRHAHMAHAAMPG
MMAR_1997|M.marinum_M RAVVDWRGQIVTMLDRCYLTQAIPVQIIWGSRDAVVPVRHAEMAHAAMPG
MUL_3358|M.ulcerans_Agy99 RAVVDWRGQIVTMLDRCYLTQAIPVQIIWGSRDAVVPVRHAEMAHAAMPG
MAV_4567|M.avium_104 RSVVDYRGQAVSALNRLRLREELPVMAIWGERDGIIPVDHAYAAHEARTD
MSMEG_1570|M.smegmatis_MC2_155 TD------------EQLRAVDLPVLALIAGSSVMLDPQRAVARARALLPR
TH_1700|M.thermoresistible__bu SD------------DQLRSVTRPVLALIAGRSVMLDAQRATRRARSMLPH
MAB_3742c|M.abscessus_ATCC_199 SD------------KQLRRLSMPVLTVIAGRTIVHDARRAAQRARSAVPD
.: : * * . *: .
Mflv_3952|M.gilvum_PYR-GCK SRLEIFEGAGHFPFHDEPDRFVELVEKFIDSTEPAVYDQEYLRTLLRTGT
Mvan_2445|M.vanbaalenii_PYR-1 SRLEVFEGSGHFPFHDDPDRFVEVVEKFIDTSEPAVYDHEYLRGLLRAGI
Mb2734|M.bovis_AF2122/97 SQLEIFEGSGHFPFHDDPARFIDIVERFMDTTEPAEYDQAALRALLRRGG
Rv2715|M.tuberculosis_H37Rv SQLEIFEGSGHFPFHDDPARFIDIVERFMDTTEPAEYDQAALRALLRRGG
MMAR_1997|M.marinum_M SKLEVFEGSGHFPFHDDPARFIDIVLRFIDSTQPPEYDQAALRELLRTGG
MUL_3358|M.ulcerans_Agy99 SKLEVFEGSGHFPFHDDPARFIDIVLRFIDSTQPPEYDQAALRELLRTGG
MAV_4567|M.avium_104 ARLEVLPDVGHFAQVEAPMRVVELIEDFIATGE-------------RR--
MSMEG_1570|M.smegmatis_MC2_155 GQVELWPDASHAINGEYPDEIAERARRMWDQVDG--VRRG----------
TH_1700|M.thermoresistible__bu GEVELWPAASHAINGEYPERIAQRAAEFWTRVDSDSPHRG----------
MAB_3742c|M.abscessus_ATCC_199 NRVHVWPDASHALNGEFPGRISELTHEFLDTVEAA---------------
.:.: .* : * .. : : :
Mflv_3952|M.gilvum_PYR-GCK SENTLSGDVDTQVAVLDAIGADERSAT
Mvan_2445|M.vanbaalenii_PYR-1 SEGTISGPADTRVAVLDAMGADERSAT
Mb2734|M.bovis_AF2122/97 GEATVTGSADTRVAVLNAIGSNERSAT
Rv2715|M.tuberculosis_H37Rv GEATVTGSADTRVAVLNAIGSNERSAT
MMAR_1997|M.marinum_M GERTVSGPADTRVAVLSAMGSDERSAT
MUL_3358|M.ulcerans_Agy99 GERTVSDPADTRVAVLSAMGSDERSAT
MAV_4567|M.avium_104 -DATSPQPG------------------
MSMEG_1570|M.smegmatis_MC2_155 ---------------------------
TH_1700|M.thermoresistible__bu ---------------------------
MAB_3742c|M.abscessus_ATCC_199 ---------------------------