For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_1700 | - | - | 100% (314) | carboxylesterase |
| M. thermoresistible (build 8) | TH_4528 | - | 3e-09 | 24.51% (253) | PUTATIVE alpha/beta hydrolase fold |
| M. thermoresistible (build 8) | TH_4292 | - | 1e-05 | 31.53% (111) | PUTATIVE putative epoxide hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2734 | - | 7e-07 | 30.77% (143) | hydrolase |
| M. gilvum PYR-GCK | Mflv_1348 | - | 3e-14 | 29.46% (241) | 3-oxoadipate enol-lactonase |
| M. tuberculosis H37Rv | Rv2715 | - | 7e-07 | 30.77% (143) | hydrolase |
| M. leprae Br4923 | MLBr_01921 | - | 6e-06 | 31.30% (115) | hypothetical protein MLBr_01921 |
| M. abscessus ATCC 19977 | MAB_3742c | - | 9e-83 | 50.00% (306) | hypothetical protein MAB_3742c |
| M. marinum M | MMAR_4778 | bphD_1 | 9e-09 | 24.28% (276) | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase BphD_1 |
| M. avium 104 | MAV_0877 | - | 6e-08 | 24.08% (245) | 2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase |
| M. smegmatis MC2 155 | MSMEG_1570 | - | 1e-107 | 63.40% (306) | carboxylesterase |
| M. ulcerans Agy99 | MUL_3358 | - | 1e-06 | 30.34% (145) | hydrolase |
| M. vanbaalenii PYR-1 | Mvan_5882 | - | 5e-12 | 30.32% (277) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
TH_1700|M.thermoresistible__bu MTPTDLAVPDVRIG---PHRDIGHFRDAAAFDRFLEVYRRGMATLPTFE-
MSMEG_1570|M.smegmatis_MC2_155 ---MEVAVPQVNIASRWSRGGLGAFVGETAFAHYLDAYRAGMALLPPHE-
MAB_3742c|M.abscessus_ATCC_199 --MSPVAVPEHRVGKHWAVQKLGHFVDASGYARFVAAYRAGMARLPQIAR
Mb2734|M.bovis_AF2122/97 ------------------------------MTERKRNLRPVRDVAPPTL-
Rv2715|M.tuberculosis_H37Rv ------------------------------MTERKRNLRPVRDVAPPTL-
MUL_3358|M.ulcerans_Agy99 ------------------------------MTERKRNLRPVREVTAPSL-
MMAR_4778|M.marinum_M ------------------------------MTDFESVWSDLQGVMFEQG-
MAV_0877|M.avium_104 ------------------------------MAEFESIWSDLQGVAFEQG-
Mflv_1348|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5882|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01921|M.leprae_Br4923 --------------------------------------------------
TH_1700|M.thermoresistible__bu VRDVTTAFGTVRAYRFDGP-AGPPVVLLPGRNAATPMYRGNLPTLLRQRT
MSMEG_1570|M.smegmatis_MC2_155 TFDVPTAFGTVRSYRFAGPECGAPVVLLPGRNAAAPMYATNLTALLRHRT
MAB_3742c|M.abscessus_ATCC_199 SFDVPTRLGSVRAYRFGAC-GGVPLLLLTGRGGSTPLWRANLTSLLSRRS
Mb2734|M.bovis_AF2122/97 --QFRTVHGYRRAFRIAG--SGPAILLIHGIGDNSTTWNGVHAKLAQRFT
Rv2715|M.tuberculosis_H37Rv --QFRTVHGYRRAFRIAG--SGPAILLIHGIGDNSTTWNGVHAKLAQRFT
MUL_3358|M.ulcerans_Agy99 --QFRTIHGYKRAFRIAG--SGPAILLIHGIGDNSTTWTGIHAKLAQRFT
MMAR_4778|M.marinum_M --YLTTAQGVRTRYLRAGEPDRPLLMLLHGSGGHAEAYVRNLAAHAEHFW
MAV_0877|M.avium_104 --YLD-AGGIRTRYLRAGDPGKPVLVLLHGSGGHAEAYVRNLAAHADHFW
Mflv_1348|M.gilvum_PYR-GCK ------MSAVDVHVIESGLPDGPAVVLSNSLGATHRMWDAQLDALERRFR
Mvan_5882|M.vanbaalenii_PYR-1 -MPLVPTRAGTLAYHVRG--SGPTVVLLPAALHDHHDFDAVSADLARHHR
MLBr_01921|M.leprae_Br4923 -------MSTNLLTLRGG--RGKPLILVHGLMGRGNTWSRQLPWLSQLGT
. . ::* . :
TH_1700|M.thermoresistible__bu VYGIDLLGEAGLSVQHTPIRSADD--IAHWLDDALAGLGLPHAHLLGVSI
MSMEG_1570|M.smegmatis_MC2_155 VYAVDLLGEAGLSVQHTPIRTVED--QARWLDDALGGLGLDRAHLFGVSV
MAB_3742c|M.abscessus_ATCC_199 VYCIDLLGEPGMSVQDKPITGPQD--HADWLEDVMAGLNLGAVHVVGLSI
Mb2734|M.bovis_AF2122/97 VIAPDLLG-HGQSDKPRADYSVAA--YANGMRDLLSVLDIERVTIVGHSL
Rv2715|M.tuberculosis_H37Rv VIAPDLLG-HGQSDKPRADYSVAA--YANGMRDLLSVLDIERVTIVGHSL
MUL_3358|M.ulcerans_Agy99 VIAPDLLG-HGRSDKPRADYSIAA--YANGMRDLLSVLDIERVTIIGHSL
MMAR_4778|M.marinum_M TWAIDMLG-HGYTDKPGHPLEIRH--YVEHLMAVLRAIGAQRASISGESL
MAV_0877|M.avium_104 TWSIDMLG-HGYTDKPGHPLEVRH--YVEHLMTVLRTIGVERASISGESL
Mflv_1348|M.gilvum_PYR-GCK VLRYDTRG-HGASPVPDGPYSIDD--LADDVVGILDRRGIDTAHLVGLSL
Mvan_5882|M.vanbaalenii_PYR-1 VVAVDWPG-CGDSPPAPDPHAVTAPVLADGLEDLVAGLGEEPVVLIGNSV
MLBr_01921|M.leprae_Br4923 VYTYDAPWHRGRNVVDPYPISTER--FVTDLADAVSTLGVP-ARLVGHSM
. * * . . : : . . : * *:
TH_1700|M.thermoresistible__bu GGWTAMNLAVRRPQRVASLTLLDPVFTFAPVR-TTPMLASIALIAPGVP-
MSMEG_1570|M.smegmatis_MC2_155 GGWTAVNAAVHRPGRIASLTLLDPVFTFVRIP-LAPIAASVLMFAPGVP-
MAB_3742c|M.abscessus_ATCC_199 GGWAAVNHAIRYPCRVRSLVLLDPALTFAPLT-WKMVLVSLGSVIPGTP-
Mb2734|M.bovis_AF2122/97 GGGVAMQFAYQFPQLVDRLILVSAGGVTKDVN-IVFRLASLPMGSEAMAL
Rv2715|M.tuberculosis_H37Rv GGGVAMQFAYQFPQLVDRLILVSAGGVTKDVN-IVFRLASLPMGSEAMAL
MUL_3358|M.ulcerans_Agy99 GGGVAMQFAYQFPQLVDRLILVGAGGVTKDVN-VVFRLASLPMGAEALAL
MMAR_4778|M.marinum_M GGWVAARAAVDHPEAVERLVLNTAGGSQADPE-VMARIVTLSMAAAENPT
MAV_0877|M.avium_104 GGWVAARAAIDHPDVVDRLVLNTAGGSQADPV-VMQRIIALSMAAAENPT
Mflv_1348|M.gilvum_PYR-GCK GGMTAMRVAARNPDRVNRMVLLCTAAELAPAQAWTDRAAAVRAGGAESVA
Mvan_5882|M.vanbaalenii_PYR-1 GGFAAARLAIRRPHRVAGLVLVNTGG-FLPIN-PIMRLFCRTLGTPQVAR
MLBr_01921|M.leprae_Br4923 GAMHSWCLAAERPDLVSALVVEDMAPDFRGCSTGPWEPWLRGIPVEFDSV
*. : * * : : :
TH_1700|M.thermoresistible__bu PALRRRVLRWISGG--ADIDAAADEAALIATASRNFVLRQPIPRSFSDDQ
MSMEG_1570|M.smegmatis_MC2_155 ERWRRRVQSWIAGG--ADLDAAAPEATLIGAGATDFTLRTPMPKLFTDEQ
MAB_3742c|M.abscessus_ATCC_199 QAIRNRLLSWSAGG--AQVDESLPEAALISAAARDFRICLPSPKVFSDKQ
Mb2734|M.bovis_AF2122/97 LRLPLVLPAVQIAG--RIVGKAIGTTSLGHDLPNVLRILDDLPEPTASAA
Rv2715|M.tuberculosis_H37Rv LRLPLVLPAVQIAG--RIVGKAIGTTSLGHDLPNVLRILDDLPEPTASAA
MUL_3358|M.ulcerans_Agy99 LRLPMVLPTVQLAG--KVLGMALGSTALGQDLPNVLRILDDLPEPTASSA
MMAR_4778|M.marinum_M WETVQARIKWLMADKSKDYDDLVASRQRIYRQPGFVAAMRDIMALQDPQI
MAV_0877|M.avium_104 WETVQARIKWLMADKSRDYDDLVASRQRVYRQPGFVAAMRDIMALQDPEI
Mflv_1348|M.gilvum_PYR-GCK PAVIARWFTLSHLETHPAERAEWVDMIAATPAEGYASCCEAIAELDLREQ
Mvan_5882|M.vanbaalenii_PYR-1 RILPAFIRLYMQADN-DLARAARDRAVTRAKTTSGVAMTAALWRSFATDA
MLBr_01921|M.leprae_Br4923 EKVFDEFGPVAGQYFLDAFDRTSTGWQLHGHTSRWIEIAAEWGTRDYWEH
TH_1700|M.thermoresistible__bu LR----------------------SVTRPVLALIAGRSVMLDAQRATRRA
MSMEG_1570|M.smegmatis_MC2_155 LR----------------------AVDLPVLALIAGSSVMLDPQRAVARA
MAB_3742c|M.abscessus_ATCC_199 LR----------------------RLSMPVLTVIAGRTIVHDARRAAQRA
Mb2734|M.bovis_AF2122/97 FGRTLRAVVDWRGQMVTMLDRCYLTEAIPVQIIWGTKDVVLPVR-HAHMA
Rv2715|M.tuberculosis_H37Rv FGRTLRAVVDWRGQMVTMLDRCYLTEAIPVQIIWGTKDVVLPVR-HAHMA
MUL_3358|M.ulcerans_Agy99 FTRTLRAVVDWRGQIVTMLDRCYLTQAIPVQIIWGSRDAVVPVR-HAEMA
MMAR_4778|M.marinum_M RARNLLGPAEYG------------AIKAPTLVLWTSHDPTADVT-EGRRI
MAV_0877|M.avium_104 RARNILGPAEYG------------SIIAPTLVLWTSDDPTADVS-EGRRI
Mflv_1348|M.gilvum_PYR-GCK LP----------------------TITAPTLAIAGADDPATPPA-KLEQI
Mvan_5882|M.vanbaalenii_PYR-1 HDLRRDAD----------------KLTAPALIVWGSRDTAIPLP-IGRAT
MLBr_01921|M.leprae_Br4923 WL----------------------AVRSPVLLIEAG--TSVTPHGQMLAM
*. :
TH_1700|M.thermoresistible__bu RSMLPHGEVELWPAASHAINGEYPERIAQRAAEFWTRVDSDSPHRG----
MSMEG_1570|M.smegmatis_MC2_155 RALLPRGQVELWPDASHAINGEYPDEIAERARRMWDQVDG--VRRG----
MAB_3742c|M.abscessus_ATCC_199 RSAVPDNRVHVWPDASHALNGEFPGRISELTHEFLDTVEAA---------
Mb2734|M.bovis_AF2122/97 HAAMPGSQLEIFEGSGHFPFHDDPARFIDIVERFMDTTEPAEYDQAALRA
Rv2715|M.tuberculosis_H37Rv HAAMPGSQLEIFEGSGHFPFHDDPARFIDIVERFMDTTEPAEYDQAALRA
MUL_3358|M.ulcerans_Agy99 HAAMPGSKLEVFEGSGHFPFHDDPARFIDIVLRFIDSTQPPEYDQAALRE
MMAR_4778|M.marinum_M ASMIPGARFEVMSGCGHWPQYEDAKSFNRRHLDFLMGH------------
MAV_0877|M.avium_104 ASMIPGARFEVMPGCGHWPQYEDAKTFNRLHLDFLLGR------------
Mflv_1348|M.gilvum_PYR-GCK VSAIPGARLLVVDGAAHLANAEQPEQITPAIIEHLEQR------------
Mvan_5882|M.vanbaalenii_PYR-1 HTALPRARFETLP-TGHVPFASAPQDFLAILRPFLTRTLGTTAGSPHQ--
MLBr_01921|M.leprae_Br4923 TKTACRTTYLYVPEAGHLIHDEATQVYRQAVVSFLAGCAGRD--------
.* . .
TH_1700|M.thermoresistible__bu ---------------------------------
MSMEG_1570|M.smegmatis_MC2_155 ---------------------------------
MAB_3742c|M.abscessus_ATCC_199 ---------------------------------
Mb2734|M.bovis_AF2122/97 LLRRGGGEATVTGSADTRVAVLNAIGSNERSAT
Rv2715|M.tuberculosis_H37Rv LLRRGGGEATVTGSADTRVAVLNAIGSNERSAT
MUL_3358|M.ulcerans_Agy99 LLRTGGGERTVSDPADTRVAVLSAMGSDERSAT
MMAR_4778|M.marinum_M ---------------------------------
MAV_0877|M.avium_104 ---------------------------------
Mflv_1348|M.gilvum_PYR-GCK ---------------------------------
Mvan_5882|M.vanbaalenii_PYR-1 ---------------------------------
MLBr_01921|M.leprae_Br4923 ---------------------------------