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VRIRRHAAVADGIAEQIRTGALPAGTRLPTHRALAARHGIAVATASRVYRDLTASGLVVGEPGRGTFVRD LSGFAGLEPARLSAGQRTADLSFNQPLSTGQDDELRQALRGLAAEGDLTSLLYQQPPGGRSRDRAAIASY LLGRGIDVAPHSVLITGGAQQGLDALLVALAEPRAVVAVDALTYPGIRMLATARHLDLAAVRADTTGMDI DHLEWLCGQRPISMLYLIPTLHNPLGYILGASARQRIAALAARHDFHIIEDATYAFLEPAAPPPVQTVAP ERTFYIGSMSKNLASGLRIGYVVAPLARRPALIRSLRATSWGASSIASALTTRWLTDGTAAKLEKQRRED ARQRQVIARAELAGLDYHAHPASYSGWLTLPEHARSDVIAHELAEHGIMVTTADAFATTAHAPNALRLAL ATPELSELTAALRHIRTATT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3582 | - | - | 100% (440) | GntR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0196c | - | 3e-23 | 27.00% (400) | GntR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0810c | - | 7e-23 | 25.26% (479) | GntR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0881c | - | 3e-08 | 28.07% (228) | aminotransferase |
| M. gilvum PYR-GCK | Mflv_1181 | - | 7e-25 | 27.32% (399) | GntR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0858c | - | 4e-08 | 28.07% (228) | aminotransferase |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_2376 | - | 4e-12 | 24.68% (385) | GntR family transcriptional regulator |
| M. avium 104 | MAV_3214 | - | 3e-14 | 26.61% (387) | GntR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_5760 | - | 3e-29 | 28.86% (447) | GntR-family protein regulator |
| M. thermoresistible (build 8) | TH_4188 | - | 4e-08 | 37.33% (75) | PUTATIVE transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_1552 | - | 2e-12 | 24.68% (385) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5625 | - | 5e-27 | 28.26% (407) | GntR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2376|M.marinum_M ------------MPVQYR-----IAGGGAESIAASIESAISQGGLAPGDA
MUL_1552|M.ulcerans_Agy99 ------------MPVQNR-----IAGGGAGSIAASIESAISQGGLAPGDA
MAV_3214|M.avium_104 ------------MAVQKS-----ITGTGAESIAASIEAAISAGSLAPGDA
Mflv_1181|M.gilvum_PYR-GCK MVSSWSNSGSRDLHLDLREALRPGARGNRNALVAALREAVRSGRLSAGTT
Mvan_5625|M.vanbaalenii_PYR-1 -MTSWANSATRDLHLDLRDALVPGARGTKDALISALRDAARSGRLTAGTM
MSMEG_5760|M.smegmatis_MC2_155 ----MDRIAGLDLHLDR-----PAGR-TREALMDAVRDAIRSGRLVSGTR
Mb0881c|M.bovis_AF2122/97 -------------------------------------MTVSRLRPYATTV
Rv0858c|M.tuberculosis_H37Rv -------------------------------------MTVSRLRPYATTV
MAB_3582|M.abscessus_ATCC_1997 -----------------------MRIRRHAAVADGIAEQIRTGALPAGTR
TH_4188|M.thermoresistible__bu ----------------------VRPRPAYQVLRDRLRDDIAAGRYRDGTR
MMAR_2376|M.marinum_M LPSIREVAGQLGVNPNTVAAAYRLLRDRGTVETAGRRGTRVRDRPASTPR
MUL_1552|M.ulcerans_Agy99 LPSIREVAGQLGVNPNTVAAAYRLLRDRGTVETAGRRGTRVRDRPASTPR
MAV_3214|M.avium_104 LPPVRELAARLGVNANTAAAAYRLLRHRGAVETAGRRGTRVRHRPATTPR
Mflv_1181|M.gilvum_PYR-GCK LPPSRALAADLGLARNTVADAYAELVAEGWLASRQGAGTWVVDTARASSQ
Mvan_5625|M.vanbaalenii_PYR-1 LPSSRTLATDLGLARNTVAEAYAELVAEGWLASRQGAGTWVADVT----T
MSMEG_5760|M.smegmatis_MC2_155 LPSSRALAADLGVARNTVARAYAELIAEGWLTSQHGSHTTVSQRAAEAVR
Mb0881c|M.bovis_AF2122/97 FAEMSALATRIGAVN----------LGQGFPDEDGPPKMLQAAQDAIAGG
Rv0858c|M.tuberculosis_H37Rv FAEMSALATRIGAVN----------LGQGFPDEDGPPKMLQAAQDAIAGG
MAB_3582|M.abscessus_ATCC_1997 LPTHRALAARHGIAVATASRVYRDLTASGLVVGEPGRGTFVRDLSGFAGL
TH_4188|M.thermoresistible__bu LPTESELMAQYGVSRQTVRRAFQDLVAEGSVYRVPGRGTYAADRYLR---
:. : * *
MMAR_2376|M.marinum_M SSLDLGVPAGAR-----DLSTGNPAPELLP---------LAAVG-WPDGS
MUL_1552|M.ulcerans_Agy99 SSLDLGVPAGAR-----DLSTGNPAPELLP---------LAAVG-WPDGS
MAV_3214|M.avium_104 SLLGLDVPAGVR-----DLSTGNPHPALLP---------LAAAAPARPAS
Mflv_1181|M.gilvum_PYR-GCK PPPVPPRPHGARVAPVHNLMPGSPDVAEFPRSQWAASARRALTHAPTDAF
Mvan_5625|M.vanbaalenii_PYR-1 PAHTPPRPHGVRVAPTHNLMPGSPDVAEFPRSQWLASTRRALGGAPTEAL
MSMEG_5760|M.smegmatis_MC2_155 SVTPPARPRPPR-RLDHDLRPGHPDLSSFPRTEWSRAVKRALANAPSEAF
Mb0881c|M.bovis_AF2122/97 VNQYPPGP------------------------------------------
Rv0858c|M.tuberculosis_H37Rv VNQYPPGP------------------------------------------
MAB_3582|M.abscessus_ATCC_1997 EPARLSAGQRTA-----DLSFNQPLSTGQDDELRQALRGLAAEGDLTSLL
TH_4188|M.thermoresistible__bu --------------------------------------------------
MMAR_2376|M.marinum_M VLPLLYGAPAMSAELVDYARAALAADGVAADHLAVTNGALDGIERALSAN
MUL_1552|M.ulcerans_Agy99 VLPLLYGAPAMSAELVDYARAALAADGVAADHLAVTNGALDGIERALSAN
MAV_3214|M.avium_104 GRAVLYGEPAISPALAEYARAALSADGVPADHLALTSGALDGIERALTAH
Mflv_1181|M.gilvum_PYR-GCK RMGDPRGRPELRSALAEYLARARGVR-TSPESLVICAGVRHAVELLARTL
Mvan_5625|M.vanbaalenii_PYR-1 RMGDPRGRPELRSALAEYLARARGVR-TSPESIVICAGVRHAVELLTRAL
MSMEG_5760|M.smegmatis_MC2_155 GYAEPQGRPELRRALAEYLARARGVR-ARPCNIVVCCGAAEGLNLVAGAL
Mb0881c|M.bovis_AF2122/97 ------GSAPLRRAIAAQRRRHFGVDYDPETEVLVTVGATEAIAAAVLGL
Rv0858c|M.tuberculosis_H37Rv ------GSAPLRRAIAAQRRRHFGVDYDPETEVLVTVGATEAIAAAVLGL
MAB_3582|M.abscessus_ATCC_1997 YQQPPGGRSRDRAAIASYLLG-RGID-VAPHSVLITGGAQQGLDALLVAL
TH_4188|M.thermoresistible__bu ----QFGSIEDLMALSD------------DTTMEVRSGLRRRVDVDAASR
* : : : * :
MMAR_2376|M.marinum_M LRPG-DRVAVEDPGWANLLDLLAALGLPVEPMGVDDDGP----LVADLQR
MUL_1552|M.ulcerans_Agy99 LRPG-DRVAVEDPGWANLLDLLAALGLPVEPMGVDDDGP----LVADLQR
MAV_3214|M.avium_104 LRPG-DRVAVEDPGWANLLDLLAALGFSAEPVRVDDAGP----LPEDLAR
Mflv_1181|M.gilvum_PYR-GCK G----GPVAVEAYGLFVFRDAIAACGVQTVPIGVDDDGA----VIADLDD
Mvan_5625|M.vanbaalenii_PYR-1 G----GPIAVESYGLFVFRDAIAAAGASTVPIGVDDRGA----VVDELDG
MSMEG_5760|M.smegmatis_MC2_155 AEMGVAATAVEAYGLPTQRAALARAGLRCPPLAVDADGA----DINALNT
Mb0881c|M.bovis_AF2122/97 VEPG-SEVLLIEPFYDSYSPVVAMAGAHRVTVPLVPDGRGFALDADALRR
Rv0858c|M.tuberculosis_H37Rv VEPG-SEVLLIEPFYDSYSPVVAMAGAHRVTVPLVPDGRGFALDADALRR
MAB_3582|M.abscessus_ATCC_1997 AEPR-AVVAVDALTYPGIRMLATARHLDLAAVRADTTGM----DIDHLEW
TH_4188|M.thermoresistible__bu LR-----LDDDVVHTVVFRRLHAGAPFVSTVVHLPDRAA-----------
: : .
MMAR_2376|M.marinum_M ALG-RGVRAVVVTSRAQNPTGAALSAARAEELREVLSQGAEEVLLVEDDH
MUL_1552|M.ulcerans_Agy99 ALG-RGVRAVVVTSRAQNPTGAALSAARAEELREVLSQGAEEVLLVEDDH
MAV_3214|M.avium_104 ALG-RGARALVLTTRAQNPTGAALSAERAAALRDLLSGRADDVLLVEDDH
Mflv_1181|M.gilvum_PYR-GCK T----SARSVLLTPAHHNPLGMPLHPSRRAAVIEWATRTGGYILDDDYDG
Mvan_5625|M.vanbaalenii_PYR-1 L----DVPAVLLTPAHHNPLGMPLHSSRRTAVIEWAQRTGGFVLDDDYDG
MSMEG_5760|M.smegmatis_MC2_155 MP---EVGAVLLTPSHQFPLGVPLHSDRRAAVIDWARRTGGMIIEDDYDG
Mb0881c|M.bovis_AF2122/97 AVT-PRTRALIIN-SPHNPTGAVLSATELAAIAEIAVAANLVVITDEVYE
Rv0858c|M.tuberculosis_H37Rv AVT-PRTRALIIN-SPHNPTGAVLSATELAAIAEIAVAANLVVITDEVYE
MAB_3582|M.abscessus_ATCC_1997 LCGQRPISMLYLIPTLHNPLGYILGASARQRIAALAARHDFHIIEDATYA
TH_4188|M.thermoresistible__bu ---------------------HHLHGCAELRTGAVSTHTVIGLLEPHLEE
* ::
MMAR_2376|M.marinum_M CAGIAGV---PLHTLAGAT-QHWAFVRSAAKAYGPDLRLAVLAGDQRTVE
MUL_1552|M.ulcerans_Agy99 CAGIAGV---PLHTLAGAT-QHWAFVRSAAKAYGPDLRLAVLAGDQRTVE
MAV_3214|M.avium_104 CAGISGA---ALHPVAGCT-THWAFVRSASKAYGPDLRVAVLAGDQRTVD
Mflv_1181|M.gilvum_PYR-GCK EFRYDRQ---PVGALQALRPDRVAYLGSTSKSLSQALRLGWMALPAELVD
Mvan_5625|M.vanbaalenii_PYR-1 EFRYDRQ---PVGALQSLRPDRVAYLGSTSKSLSQTLRLGWMALPDNLID
MSMEG_5760|M.smegmatis_MC2_155 EFRYDRS---PVGALHGVDPAHVIYLGTASKSLAPGLRLGWLVLPDRLVD
Mb0881c|M.bovis_AF2122/97 HLVFDHARHLPLAGFDGMAERTITISSAAKMFNCTGWKIGWACGPAELIA
Rv0858c|M.tuberculosis_H37Rv HLVFDHARHLPLAGFDGMAERTITISSAAKMFNCTGWKIGWACGPAELIA
MAB_3582|M.abscessus_ATCC_1997 FLEPAAP-----PPVQTVAPERTFYIGSMSKNLASGLRIGYVVAPLARRP
TH_4188|M.thermoresistible__bu PIDQAAQ------------------------------SITVAPADDDTAD
:
MMAR_2376|M.marinum_M RVHGRLRLGPGWVSHILQDLAVRLFADDAATGLVRQAQERYADARGRLCA
MUL_1552|M.ulcerans_Agy99 RVHGRLRLGPGWVSHILQDLAVRLFADDAATGLVRQAQERYADARGRLCA
MAV_3214|M.avium_104 RVHGRLRLGPGWVSHVLQQLAVELWSDTAASELVATAERRYADRRRRLCG
Mflv_1181|M.gilvum_PYR-GCK QVVETAGGQQFHVDVVSQLTLADFLTAGHYDRHIRRMRMRYRRRRDMLVS
Mvan_5625|M.vanbaalenii_PYR-1 AVLAAAGGQQFYVDAINQLTLADFIAGGHYDRHIRRMRMRYRRRRDVLVS
MSMEG_5760|M.smegmatis_MC2_155 AVLRQKGETEETSGFVDQLTMAEFIESGSYDRHIRTMRAQYRRRREQLVA
Mb0881c|M.bovis_AF2122/97 GVRAAKQYLSYVGGAPFQPAVALALDT--EDAWVAALRNSLRARRDRLAA
Rv0858c|M.tuberculosis_H37Rv GVRAAKQYLSYVGGAPFQPAVALALDT--EDAWVAALRNSLRARRDRLAA
MAB_3582|M.abscessus_ATCC_1997 ALIRSLRATSWGASSIASALTTRWLTDGTAAKLEKQRREDARQRQVIARA
TH_4188|M.thermoresistible__bu AVGVEPGHPMLRIDRLYSDRTGRPVELSVSHFLPEQYTYRVTLRRE----
: . . :
MMAR_2376|M.marinum_M ALSARGVA---AHGRSGLNVWIPVPD--ETAAITRLLNRGWAAAPGARFR
MUL_1552|M.ulcerans_Agy99 ALSARGVA---AHGRSGLNVWIPVPD--ETAAITRLLNRGWAAAPGARFR
MAV_3214|M.avium_104 ALAERGVD---AHGRSGLNVWVRVPD--EAVAVSRLLGAGWAAAPGARFR
Mflv_1181|M.gilvum_PYR-GCK ALSPFAVG--IGGLAAGVNLLVTLPDGAEPELIRRAGEAGIALVGLSMMR
Mvan_5625|M.vanbaalenii_PYR-1 ALSPFDVG--IGGLAAGVNLLVTLPDGAEPEVMRRAGESGLAVSGLSIMR
MSMEG_5760|M.smegmatis_MC2_155 AVTAASPATTVAGLPAGLHVMLEIAGANASALAHQLAWRRLGVESLDRYR
Mb0881c|M.bovis_AF2122/97 GLTEIGFAVHDSYGTYFLCADPRPLGYDDSTEFCAALPEKVGVAAIPMSA
Rv0858c|M.tuberculosis_H37Rv GLTEIGFAVHDSYGTYFLCADPRPLGYDDSTEFCAALPEKVGVAAIPMSA
MAB_3582|M.abscessus_ATCC_1997 ELAGLDYH---AHPASYSGWLTLPEHARSDVIAHELAEHGIMVTTADAFA
TH_4188|M.thermoresistible__bu --------------------------------------------------
MMAR_2376|M.marinum_M IRSAPGIRVTIAGLSAEEIEPL-----ADAIAEAIQRTGRPTV----
MUL_1552|M.ulcerans_Agy99 VRSAPGIRVTIAGLSAEEIEPL-----ADAIAGAIQRTGRPTV----
MAV_3214|M.avium_104 MQTPAGIRITIADLTPDEIEPL-----ADAVAQAVRPSGRPIV----
Mflv_1181|M.gilvum_PYR-GCK HPRAGSGVAERDGLIVGFAAAP-----EHAFPAAVSALCEVLRASGL
Mvan_5625|M.vanbaalenii_PYR-1 HPMAGP--ADVDGLIVGFAAPP-----EHAFSAAVAALCDVLRASGL
MSMEG_5760|M.smegmatis_MC2_155 HPEFDN---ERSGLVFSYAAPS-----PSAWSAALDAVVRLLP----
Mb0881c|M.bovis_AF2122/97 FCDPAAGQASQQADVWNHLVRFTFCKRDDTLDEAIRRLSVLAERPAT
Rv0858c|M.tuberculosis_H37Rv FCDPAAGQASQQADVWNHLVRFTFCKRDDTLDEAIRRLSVLAERPAT
MAB_3582|M.abscessus_ATCC_1997 TTAHAP-----NALRLALATPE-----LSELTAALRHIRTATT----
TH_4188|M.thermoresistible__bu -----------------------------------------------