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SSWANSAKAESRPLSHDLHLDLRQSITPGTRGVRELLTSALRDAVRSGRLTVGSMLPPSRTLASDLGLAR NTVAEAYAELVAEGWLESRQGSGTRVVNRGKDQLPPRPRGAGTPPPHNLMPGSGDVTAFPRADWLASARR ALNHAPHEALRVGDPRGRHELRSAVAEYVSRVRGVRTTPDSILICAGTRHAVEILTRMYGLARPIAVEAY GLFIFRDCIEATGGSSTPIGFDGEGAVVSDLENLDTSAALITPAHHFPHGLPLHPARRTAVVDWARRTDS YVLEDDYDGEFRYDRQPVGALQSLDPDRVVYLGSASKSLAPALRLGWMVLPPEQMDAAVAATGGAQWYVG AISQLTMADFIAGGHYDRHIRRMRGRYRRRRDLLVQRLAGYNVGVRGLSAGLHLLLTLPEGTESDVLYRA GEAGVALAGLARLRHPLAGPHIPNPDGVVVSFGTPADHGFGPAVDALCRVLAATGL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0196c | - | - | 100% (477) | GntR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1353c | - | 4e-47 | 32.74% (391) | GntR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3582 | - | 4e-23 | 27.00% (400) | GntR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1183 | - | 7e-07 | 42.47% (73) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_1181 | - | 1e-173 | 61.62% (482) | GntR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1152 | - | 7e-07 | 42.47% (73) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_01488 | - | 3e-06 | 25.61% (285) | N-succinyldiaminopimelate aminotransferase |
| M. marinum M | MMAR_2376 | - | 1e-13 | 25.55% (458) | GntR family transcriptional regulator |
| M. avium 104 | MAV_3214 | - | 2e-17 | 26.14% (459) | GntR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_6371 | - | 1e-173 | 65.08% (461) | GntR-family protein regulator |
| M. thermoresistible (build 8) | TH_1831 | - | 2e-06 | 25.83% (271) | PROBABLE AMINOTRANSFERASE |
| M. ulcerans Agy99 | MUL_1552 | - | 7e-13 | 25.17% (453) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5625 | - | 1e-178 | 65.27% (478) | GntR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1183|M.bovis_AF2122/97 -----------------MELRDWLRVDVKAG-KPLFDQLRTQVIDGVRAG
Rv1152|M.tuberculosis_H37Rv -----------------MELRDWLRVDVKAG-KPLFDQLRTQVIDGVRAG
Mflv_1181|M.gilvum_PYR-GCK MVSSWSNSG-------SRDLHLDLREALRPGARGNRNALVAALREAVRSG
Mvan_5625|M.vanbaalenii_PYR-1 -MTSWANSA-------TRDLHLDLRDALVPGARGTKDALISALRDAARSG
MSMEG_6371|M.smegmatis_MC2_155 -MTSRANSG-------ARDLELHT--VITPGSRTAREDLVTALRDGIRSG
MAB_0196c|M.abscessus_ATCC_199 -MSSWANSAKAESRPLSHDLHLDLRQSITPGTRGVRELLTSALRDAVRSG
MMAR_2376|M.marinum_M ---------------------MPVQYRIAGG---GAESIAASIESAISQG
MUL_1552|M.ulcerans_Agy99 ---------------------MPVQNRIAGG---GAGSIAASIESAISQG
MAV_3214|M.avium_104 ---------------------MAVQKSITGT---GAESIAASIEAAISAG
MLBr_01488|M.leprae_Br4923 -------------------MSPFGRVSATLPVFPWDTLADAKAVAESHPD
TH_1831|M.thermoresistible__bu --------------------------------------------------
Mb1183|M.bovis_AF2122/97 ALPPGTRLPTVRDLAGQLGVAANTVARAYRELESAAIVETRGRFGTFISR
Rv1152|M.tuberculosis_H37Rv ALPPGTRLPTVRDLAGQLGVAANTVARAYRELESAAIVETRGRFGTFISR
Mflv_1181|M.gilvum_PYR-GCK RLSAGTTLPPSRALAADLGLARNTVADAYAELVAEGWLASRQGAGTWVVD
Mvan_5625|M.vanbaalenii_PYR-1 RLTAGTMLPSSRTLATDLGLARNTVAEAYAELVAEGWLASRQGAGTWVAD
MSMEG_6371|M.smegmatis_MC2_155 RLGTGTVLPPSRVLAADLGLARNTVAEAYADLVAEGWLASRQGAGTWVAR
MAB_0196c|M.abscessus_ATCC_199 RLTVGSMLPPSRTLASDLGLARNTVAEAYAELVAEGWLESRQGSGTRVVN
MMAR_2376|M.marinum_M GLAPGDALPSIREVAGQLGVNPNTVAAAYRLLRDRGTVETAGRRGTRVRD
MUL_1552|M.ulcerans_Agy99 GLAPGDALPSIREVAGQLGVNPNTVAAAYRLLRDRGTVETAGRRGTRVRD
MAV_3214|M.avium_104 SLAPGDALPPVRELAARLGVNANTAAAAYRLLRHRGAVETAGRRGTRVRH
MLBr_01488|M.leprae_Br4923 GIVDLSVGTPVDPVAPLIQEALAAASSVAGYPTTAGTARLREAAVAALDR
TH_1831|M.thermoresistible__bu -------------VAPVIRAALAEASAAPGYPTTAGTPALRASAAAALER
:* : .: . . : :
Mb1183|M.bovis_AF2122/97 FD------------PTDAAMAAAAKEYVGVARALGLTKS----DAMRYLT
Rv1152|M.tuberculosis_H37Rv FD------------PTDAAMAAAAKEYVGVARALGLTKS----DAMRYLT
Mflv_1181|M.gilvum_PYR-GCK TARASSQPPPVPPRPHGARVAPVHNLMPGSPDVAEFPRSQWAASARRALT
Mvan_5625|M.vanbaalenii_PYR-1 VT----TPAHTPPRPHGVRVAPTHNLMPGSPDVAEFPRSQWLASTRRALG
MSMEG_6371|M.smegmatis_MC2_155 TE----APRLTPP-PLRIAGTPKHNLMPGSPDVAEFPRTAWLASARRALS
MAB_0196c|M.abscessus_ATCC_199 RG-----KDQLPPRPRGAGTPPPHNLMPGSGDVTAFPRADWLASARRALN
MMAR_2376|M.marinum_M RP----------------ASTPRSSLDLGVPAGARDLSTGNPAPELLPLA
MUL_1552|M.ulcerans_Agy99 RP----------------ASTPRSSLDLGVPAGARDLSTGNPAPELLPLA
MAV_3214|M.avium_104 RP----------------ATTPRSLLGLDVPAGVRDLSTGNPHPALLPLA
MLBr_01488|M.leprae_Br4923 RYG-----------------------ITGLTEAAVLPVIGTKELIAWLPT
TH_1831|M.thermoresistible__bu RYG-----------------------ITGLTPDAVLPAIGTKELIAWLPT
.
Mb1183|M.bovis_AF2122/97 HVP--DD-------------------------------------------
Rv1152|M.tuberculosis_H37Rv HVP--DD-------------------------------------------
Mflv_1181|M.gilvum_PYR-GCK HAP--TDAFRMGDPRGRPELRSALAEYLARARGVR-TSPESLVICAGVRH
Mvan_5625|M.vanbaalenii_PYR-1 GAP--TEALRMGDPRGRPELRSALAEYLARARGVR-TSPESIVICAGVRH
MSMEG_6371|M.smegmatis_MC2_155 NAP--ASALRMGDPRGRLELRSALAEYLGRVRGVR-TTSESIVICSGVRN
MAB_0196c|M.abscessus_ATCC_199 HAP--HEALRVGDPRGRHELRSAVAEYVSRVRGVR-TTPDSILICAGTRH
MMAR_2376|M.marinum_M AVG-WPDGSVLPLLYGAPAMSAELVDYARAALAADGVAADHLAVTNGALD
MUL_1552|M.ulcerans_Agy99 AVG-WPDGSVLPLLYGAPAMSAELVDYARAALAADGVAADHLAVTNGALD
MAV_3214|M.avium_104 AAAPARPASGRAVLYGEPAISPALAEYARAALSADGVPADHLALTSGALD
MLBr_01488|M.leprae_Br4923 LLG-----LRAGDVVVVPELAYPTYNVGARLAGARVLRADSLTQLG----
TH_1831|M.thermoresistible__bu LLG-----LGGDDTVVVPELAYPTYDVGARLAGARVFRADSLTQLG----
Mb1183|M.bovis_AF2122/97 --------------------------------------------------
Rv1152|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1181|M.gilvum_PYR-GCK AVE-LLARTLG--GPVAVEAYGLFVFRDAIAACGVQTVPIGVDDDGAVIA
Mvan_5625|M.vanbaalenii_PYR-1 AVE-LLTRALG--GPIAVESYGLFVFRDAIAAAGASTVPIGVDDRGAVVD
MSMEG_6371|M.smegmatis_MC2_155 GVE-LLGKVFGTQRSIAVEAYGLFIFRDALAAMGIATAPIGLDEHGAVIS
MAB_0196c|M.abscessus_ATCC_199 AVE-ILTRMYGLARPIAVEAYGLFIFRDCIEATGGSSTPIGFDGEGAVVS
MMAR_2376|M.marinum_M GIERALSANLRPGDRVAVEDPGWANLLDLLAALGLPVEPMGVDDDGPLVA
MUL_1552|M.ulcerans_Agy99 GIERALSANLRPGDRVAVEDPGWANLLDLLAALGLPVEPMGVDDDGPLVA
MAV_3214|M.avium_104 GIERALTAHLRPGDRVAVEDPGWANLLDLLAALGFSAEPVRVDDAGPLPE
MLBr_01488|M.leprae_Br4923 --------------------------------------------------
TH_1831|M.thermoresistible__bu --------------------------------------------------
Mb1183|M.bovis_AF2122/97 --------------------------------------------------
Rv1152|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1181|M.gilvum_PYR-GCK DLD---DTSARSVLLTPAHHNPLGMPLHPSRRAAVIEWATRTGGYILDDD
Mvan_5625|M.vanbaalenii_PYR-1 ELD---GLDVPAVLLTPAHHNPLGMPLHSSRRTAVIEWAQRTGGFVLDDD
MSMEG_6371|M.smegmatis_MC2_155 DLD---MLDVPAVLLTPAHHSPHGMPLHPSRRSEVIEWARRTGGYVIDDD
MAB_0196c|M.abscessus_ATCC_199 DLE---NLDTSAALITPAHHFPHGLPLHPARRTAVVDWARRTDSYVLEDD
MMAR_2376|M.marinum_M DLQRALGRGVRAVVVTSRAQNPTGAALSAARAEELREVLSQGAEEVLLVE
MUL_1552|M.ulcerans_Agy99 DLQRALGRGVRAVVVTSRAQNPTGAALSAARAEELREVLSQGAEEVLLVE
MAV_3214|M.avium_104 DLARALGRGARALVLTTRAQNPTGAALSAERAAALRDLLSGRADDVLLVE
MLBr_01488|M.leprae_Br4923 -------LQSPALFYLNSPSNPTGQVLAVNHLRKMVGWARNRGVVVVSDE
TH_1831|M.thermoresistible__bu -------PQTPALIYLNSPSNPTGRVLGVDHLRKVVGWARDRGVIVASDE
Mb1183|M.bovis_AF2122/97 --------------------------------------------------
Rv1152|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1181|M.gilvum_PYR-GCK YDGEFRYDRQPVGALQALRPDRVAYLGSTSKSLS-----QALRLGWMALP
Mvan_5625|M.vanbaalenii_PYR-1 YDGEFRYDRQPVGALQSLRPDRVAYLGSTSKSLS-----QTLRLGWMALP
MSMEG_6371|M.smegmatis_MC2_155 YDGEFRYDRQPVGALQSLDPEHVAYLGSASKSLA-----QTLRVGWMALP
MAB_0196c|M.abscessus_ATCC_199 YDGEFRYDRQPVGALQSLDPDRVVYLGSASKSLA-----PALRLGWMVLP
MMAR_2376|M.marinum_M DDHCAGIAGVPLHTLAG-ATQHWAFVRSAAKAYG-----PDLRLAVLAGD
MUL_1552|M.ulcerans_Agy99 DDHCAGIAGVPLHTLAG-ATQHWAFVRSAAKAYG-----PDLRLAVLAGD
MAV_3214|M.avium_104 DDHCAGISGAALHPVAG-CTTHWAFVRSASKAYG-----PDLRVAVLAGD
MLBr_01488|M.leprae_Br4923 CYLGLGWDAEPFSVLHPLVCDGNHTGLLAVHSLSKSSSLAGYRAGFVAGD
TH_1831|M.thermoresistible__bu CYLGLGWDETPVSVLHPTVCGGDHTNLLAIHSLSKTSSLAGYRAGFVAGD
Mb1183|M.bovis_AF2122/97 --------------------------------------------------
Rv1152|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1181|M.gilvum_PYR-GCK AELVDQVVETAGGQQFHVDVVSQLTLADFLTAGHYDRHIRRMRMRYRRRR
Mvan_5625|M.vanbaalenii_PYR-1 DNLIDAVLAAAGGQQFYVDAINQLTLADFIAGGHYDRHIRRMRMRYRRRR
MSMEG_6371|M.smegmatis_MC2_155 QALVEPVIAAAGGQQFNVDAITALTLADFIATGGYDRHIRRMRNRYRRRR
MAB_0196c|M.abscessus_ATCC_199 PEQMDAAVAATGGAQWYVGAISQLTMADFIAGGHYDRHIRRMRGRYRRRR
MMAR_2376|M.marinum_M QRTVERVHGRLRLGPGWVSHILQDLAVRLFADDAATGLVRQAQERYADAR
MUL_1552|M.ulcerans_Agy99 QRTVERVHGRLRLGPGWVSHILQDLAVRLFADDAATGLVRQAQERYADAR
MAV_3214|M.avium_104 QRTVDRVHGRLRLGPGWVSHVLQQLAVELWSDTAASELVATAERRYADRR
MLBr_01488|M.leprae_Br4923 PDLVAELLAVRKHAGMMVPTPVQAAMVAALGDDAHE---REQRDRYARRR
TH_1831|M.thermoresistible__bu PALVAELLAVRKHAGMMVPTPVQAAMVAALDDDAHE---RQQRERYQRRR
Mb1183|M.bovis_AF2122/97 --------------------------------------------------
Rv1152|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1181|M.gilvum_PYR-GCK DMLVSALSPFAVGIGGLAAGVNLLVTLPDGAEPELIRRAGEAGIALVGLS
Mvan_5625|M.vanbaalenii_PYR-1 DVLVSALSPFDVGIGGLAAGVNLLVTLPDGAEPEVMRRAGESGLAVSGLS
MSMEG_6371|M.smegmatis_MC2_155 DHLVEALSGFDVGIRGLAAGVNMLLTLPDGAEPEVLRRAGEAGIALSGLA
MAB_0196c|M.abscessus_ATCC_199 DLLVQRLAGYNVGVRGLSAGLHLLLTLPEGTESDVLYRAGEAGVALAGLA
MMAR_2376|M.marinum_M GRLCAALSARGVAAHGR-SGLNVWIPVPD--ETAAITRLLNRGWAAAPGA
MUL_1552|M.ulcerans_Agy99 GRLCAALSARGVAAHGR-SGLNVWIPVPD--ETAAITRLLNRGWAAAPGA
MAV_3214|M.avium_104 RRLCGALAERGVDAHGR-SGLNVWVRVPD--EAVAVSRLLGAGWAAAPGA
MLBr_01488|M.leprae_Br4923 DVLLPAVVSAGFTVDHSEAGLYLWASRGE-PCRDSVEWFAQRGILVALGE
TH_1831|M.thermoresistible__bu RELLPALQQAGFTVDHSEAGLYLWATRGE-PCRATVDWLARRGILVAPGE
Mb1183|M.bovis_AF2122/97 ------------------------------------------------
Rv1152|M.tuberculosis_H37Rv ------------------------------------------------
Mflv_1181|M.gilvum_PYR-GCK MMRHPRAGSGVAERDGLIVGFAAAPEHAFPAAVSALCEVLRASGL---
Mvan_5625|M.vanbaalenii_PYR-1 IMRHPMAGP--ADVDGLIVGFAAPPEHAFSAAVAALCDVLRASGL---
MSMEG_6371|M.smegmatis_MC2_155 LMRHPLAHPDIPAPDGIIVGFGAPAEHAFRPAVEALRGVLEDVLSP--
MAB_0196c|M.abscessus_ATCC_199 RLRHPLAGPHIPNPDGVVVSFGTPADHGFGPAVDALCRVLAATGL---
MMAR_2376|M.marinum_M RFR-------IRSAPGIRVTIAGLSAEEIEPLADAIAEAIQRTGRPTV
MUL_1552|M.ulcerans_Agy99 RFR-------VRSAPGIRVTIAGLSAEEIEPLADAIAGAIQRTGRPTV
MAV_3214|M.avium_104 RFR-------MQTPAGIRITIADLTPDEIEPLADAVAQAVRPSGRPIV
MLBr_01488|M.leprae_Br4923 FYG-------PGGCQHVRVALTAS-DERIAAVVARLS-----------
TH_1831|M.thermoresistible__bu FYG-------PRGAEHVRIALTAP-DERITAAAARLAQAG--------