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M. abscessus ATCC 19977 MAB_3575c (-)

annotation: polyketide synthase
coordinates: 3618780 - 3621758
length: 992

EIDVTGIACRFPGADGVEAFWDMLLRGRNGTRVVPEDRWWADDFVSPAPPYGTGKVNTRHGAFIDDPERF
DHGFFGIAPSEAAATDIQQRLVLQAGYHALEDAGIDPQSLRGSTTGVFVGVMSSDWGALHLTDYAGMTPQ
RGVGNGYCMLANRVSYALDLTGPSMSVDTACSSSLTAVHLAAGALRAGECDLAIVAGVNLMLTPILSIFY
TQAGLSAPDGRCRPFAKSGGGIGRGEGVGAVVLRRSEDRPDDAPAPYATVRGSFVGQDGRSNGITAPTRR
GQERVIAAALRSAGHTGADLHFVEAHGTGTTLGDLIETQALGATCGDRVGRAPLVVGSVKGNIGHTEGAA
GIAGFIKACLSMHHRTVPPSLFADDENPALDLAERNLKLAVSAEKLPRGDLLAGVSSFGLGGTNVHVVIG
SAPRVRRPIRRGGIGVLTVSGNDAAALRRNLDRLVAGFDPTEHWPRYCYSTNQVKAGGTQRIALVTRDGA
DLAGEAEVALHRLARRNERARRRRPRIAFVYTGQGSQYREMGLALREQHSGFAEALAEADALLEPHFGGS
VVRAIETGEDHLGRSLDDTVVAQPALFALQYALTTTFAAHGVRPDVVLGHSVGEIAACAAAGVLDPAAAA
ALVVTRGALMGALPAGGTMLAARLPAELADEFVSGPVALAAVNGPDSVTFSGPVERIAEVADQLNGRGVH
TRELVVSHAFHSPAMEPVGGELAAAAPLPAESAGAPIVISSVTGTAAEAADFTGDYWRAQLLGTVDFLGA
ARTLADMEPSHIIEIGPRSTLLSLLAAADLIPDSQRIAPVPGAAATGLDFADALAALWQWGLDIDWRPLY
AEHDRVVGRLPGYVFADEERFFASAATVGPLVHTQSVRTATAPVREVASVPPADDESQPDVGVVHRAVIR
VLADVGGHREDALHAAADLRDDLGFDSVQAMQFADRIVNELDMPRLDPVAIQDNLTTIADLTKLVAGTAG
VAQPEHTGAGI*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_3575c--100% (992)polyketide synthase
M. abscessus ATCC 19977MAB_0939-e-13739.43% (842) polyketide synthase
M. abscessus ATCC 19977MAB_2212-e-12336.75% (819) polyketide synthase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2074cpks121e-15040.25% (887) polyketide synthase pks12
M. gilvum PYR-GCKMflv_0405-1e-14237.99% (916) beta-ketoacyl synthase
M. tuberculosis H37RvRv2048cpks121e-15040.14% (887) polyketide synthase pks12
M. leprae Br4923MLBr_00135-1e-15139.69% (897) putative polyketide synthase
M. marinum MMMAR_0101-1e-15140.36% (892) polyketide synthase PKS
M. avium 104MAV_3108-1e-15340.65% (888) erythronolide synthase, modules 3 and 4
M. smegmatis MC2 155MSMEG_0408-1e-13836.29% (981) type I modular polyketide synthase
M. thermoresistible (build 8)TH_4458-1e-12440.38% (676) PUTATIVE putative Fatty acyl-AMP ligase FadD28_1 and polyketide
M. ulcerans Agy99MUL_2005pks15/11e-14638.80% (902) polyketide synthase Pks15/1
M. vanbaalenii PYR-1Mvan_1003-1e-14438.75% (898) beta-ketoacyl synthase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0405|M.gilvum_PYR-GCK          ----------------------MGSAAHQGE-SAHRFAIVGYAGRFPG-A
MSMEG_0408|M.smegmatis_MC2_155      ----------------------MVSAEHPIE-PTPSFAIIGYAARFPG-A
Mvan_1003|M.vanbaalenii_PYR-1       --------MTDLQKRALQAIEVLRARVRELEGAGDGYAIVGYALRFPG-A
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           MVDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGGV
Rv2048c|M.tuberculosis_H37Rv        MVDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGGV
MMAR_0101|M.marinum_M               --------------------------------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          RDAESFWELLADGRDAISEVPEDR-WDVEAFFDPDPSTPGKVVTRRAGFV
MSMEG_0408|M.smegmatis_MC2_155      ASAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRAGFV
Mvan_1003|M.vanbaalenii_PYR-1       ADADEFWDVLRGGRDAISEVPQDR-WDADEFFDADPEAAGKMVTRRAGFV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           DSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHKSYARTGGFV
Rv2048c|M.tuberculosis_H37Rv        DSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHKSYARTGGFV
MMAR_0101|M.marinum_M               --------------------------------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          DDVSGFDAPFFGMSTREVRLMDPQHRLLLETAWRAIEHSGTAPSELANTN
MSMEG_0408|M.smegmatis_MC2_155      DDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSN
Mvan_1003|M.vanbaalenii_PYR-1       EDVAGFDAPFFGVSAREAMFMDPQHRLLLETAWRAVEHSGTAPSALAGTR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           DGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSA
Rv2048c|M.tuberculosis_H37Rv        DGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSA
MMAR_0101|M.marinum_M               --------------------------------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          TGVFVGLATHDYLGMASDELSYPEIEAYMAIGTSNAAAAGRISYRLGLQG
MSMEG_0408|M.smegmatis_MC2_155      TGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQG
Mvan_1003|M.vanbaalenii_PYR-1       TGVFMGLSTHDYLGMLTDNLTHDAIEAYLGTGTSPAAAIGRISYRLGLQG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           TGVFAGLIVGGYG------MLAEEIEGYRLTGMTSSVASGRVAYVLGLEG
Rv2048c|M.tuberculosis_H37Rv        TGVFAGLIVGGYG------MLAEEIEGYRLTGMTSSVASGRVAYVLGLEG
MMAR_0101|M.marinum_M               --------------------------------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          PAVAVDTACSSSLVAIHQACQALRLGECDLALAGGANVILTPATMITFSN
MSMEG_0408|M.smegmatis_MC2_155      PAVAVDTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSN
Mvan_1003|M.vanbaalenii_PYR-1       PAVAVDTACSSSLVAVHQACQALRLAECDVALAGGVNVLLSPATMINFSR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           PAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPTVFVEFSR
Rv2048c|M.tuberculosis_H37Rv        PAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPTVFVEFSR
MMAR_0101|M.marinum_M               --------------------------------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AHMLAPDGRCKTFDAAADGYVRGEGCGVIVIKRLEDAVRDGDRIRAVIRG
MSMEG_0408|M.smegmatis_MC2_155      AHMLAPDGRCKTFDAAADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRG
Mvan_1003|M.vanbaalenii_PYR-1       ARMLAPDGRCKTFDATADGYVRGEGCGVVVVKRLADAIRHGDRIRAVIRG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           HRGLAPDGRCKPYAGRADGVGWSEGGGMLVLQRLSDARRLGHPVLAVVVG
Rv2048c|M.tuberculosis_H37Rv        HRGLAPDGRCKPYAGRADGVGWSEGGGMLVLQRLSDARRLGHPVLAVVVG
MMAR_0101|M.marinum_M               --------------------------------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          SAINQDGASGGLTVPNGVAQQRVIGDALSRAGLAPGDVDYLEAHGTGTSL
MSMEG_0408|M.smegmatis_MC2_155      SAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPADVGYLEAHGTGTSL
Mvan_1003|M.vanbaalenii_PYR-1       SAVNQDGASGGLTVPNGAAQQRVIADALTNAGLTAADVDYLEAHGTGTPL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           SAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTL
Rv2048c|M.tuberculosis_H37Rv        SAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTL
MMAR_0101|M.marinum_M               --------------------------------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GDPIEAQAAGAALGPGREPQRPLLIG-SAKTNIGHLEAAAGIAGVIKVVL
MSMEG_0408|M.smegmatis_MC2_155      GDPIEAQAAGEVLGAGRAPEEPLLIG-SAKTNIGHLEAAAGIAGVIKVVM
Mvan_1003|M.vanbaalenii_PYR-1       GDPIEVQAAGAVLGVGREPDRPLLIG-SVKTNIGHLEAASGIAGLLKVIL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           GDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAGVIKMVL
Rv2048c|M.tuberculosis_H37Rv        GDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAGVIKMVL
MMAR_0101|M.marinum_M               --------------------------------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          SLEHETLPKHLNFENPSPHIPWDRLPVEVVKESIPWRRGQRGGRPRIAGV
MSMEG_0408|M.smegmatis_MC2_155      ALENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQR---NGKPRIAGV
Mvan_1003|M.vanbaalenii_PYR-1       SLEHQVLPKHLNFRSPSPHIPWNRLPVRIVDDPVPWTR---SGRSRVAGI
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           AMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWPAG---ARTRRAGV
Rv2048c|M.tuberculosis_H37Rv        AMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWPAG---ARTRRAGV
MMAR_0101|M.marinum_M               --------------------------------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          SSFGFAGTNAHVILEEAPLAAEPAQES--VDDGRFTLLPLSARTPAALMA
MSMEG_0408|M.smegmatis_MC2_155      SSFGFAGTNAHVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVR
Mvan_1003|M.vanbaalenii_PYR-1       SSFGFSGTNAHVLVEEAPRADRAGAAPQPAAPGGFGMLPLSARTPDALAA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           SSFGISGTNAHVIIEAVPVVPRREAGWAGPVVP-----WVVSAKSESALR
Rv2048c|M.tuberculosis_H37Rv        SSFGISGTNAHVIIEAVPVVPRREAGWAGPVVP-----WVVSAKSESALR
MMAR_0101|M.marinum_M               --------------------------------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          VADRYRDWLVANPDATLADLCFTAGTARSHLEHRAALVVNTREAALDLLG
MSMEG_0408|M.smegmatis_MC2_155      LAGEYRDWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLG
Mvan_1003|M.vanbaalenii_PYR-1       TAHRLRTWLAANPDASWPDLCFTAAVGRSHLRHRAALVVDSRSSVEELLG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           GQAARLAAYVRGDDGLDVADVGWSLAGRSVFEHRAVVVGGDRDRLLAGLD
Rv2048c|M.tuberculosis_H37Rv        GQAARLAAYVRGDDGLDVADVGWSLAGRSVFEHRAVVVGGDRDRLLAGLD
MMAR_0101|M.marinum_M               --------------------------------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ALADDRPAPGLVRGESHDTPKTAWLFTGQGSQYPGMSRELFDTEPLFAET
MSMEG_0408|M.smegmatis_MC2_155      ALADDRPAPGLVRGESHEAPKTAWLFTGQGSQYPGMARELFDTEPVFAET
Mvan_1003|M.vanbaalenii_PYR-1       ALAEDRPGPGLARGECGDPPKTAWLFTGQGSQYPGMGRELFDTEPVYREV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           ELAGDQLGGSVVRGTATAAGKTVFVFPGQGSQWLGMGIELLDTAPAFAQQ
Rv2048c|M.tuberculosis_H37Rv        ELAGDQLGGSVVRGTATAAGKTVFVFPGQGSQWLGMGIELLDTAPAFAQQ
MMAR_0101|M.marinum_M               --------------------------------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LRECAAAVDGMLEKPLLDVIFDTDGVLDTDSNETLRHTSYAQPALFAVEM
MSMEG_0408|M.smegmatis_MC2_155      VRKCAEAVADILEKPLLDVIFDAD-ELDGDTESPLRHTTYAQPALFAVEL
Mvan_1003|M.vanbaalenii_PYR-1       MTRCAEAVADVLERPLLDVVFDAD------GGEALRHTSYAQPALYAVEM
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           IDACAEAFAEFVDWSLVDVLRGAP------GAPGLDRVDVVQPVLFAVMV
Rv2048c|M.tuberculosis_H37Rv        IDACAEAFAEFVDWSLVDVLRGAP------GAPGLDRVDVVQPVLFAVMV
MMAR_0101|M.marinum_M               --------------------------------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GLARLWQSWGFEPDVVLGHSVGQYAAACVAGVLSLRDGARLMAERGRLFG
MSMEG_0408|M.smegmatis_MC2_155      GLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGRLFG
Mvan_1003|M.vanbaalenii_PYR-1       GLARLWQSWGIEPDVVLGHSVGQYAAACVAGVMGLEDGAVLLAERGRLFG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           SLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRSKLLA
Rv2048c|M.tuberculosis_H37Rv        SLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRSKLLA
MMAR_0101|M.marinum_M               --------------------------------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           GLAGPGGMVSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSGEVGALE
Rv2048c|M.tuberculosis_H37Rv        GLAGPGGMVSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSGEVGALE
MMAR_0101|M.marinum_M               --------------------------------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           ELIAVCSTKELRTRRIEVDYASHSVEVEAIRGPLAEALSGIEPRSTRTVF
Rv2048c|M.tuberculosis_H37Rv        ELIAVCSTKELRTRRIEVDYASHSVEVEAIRGPLAEALSGIEPRSTRTVF
MMAR_0101|M.marinum_M               --------------------------------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           FSTVTGNRLDTAGLDADYWYRNVRQTVLFDQAVRNACEQGYRTFIESSPH
Rv2048c|M.tuberculosis_H37Rv        FSTVTGNRLDTAGLDADYWYRNVRQTVLFDQAVRNACEQGYRTFIESSPH
MMAR_0101|M.marinum_M               --------------------------------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           PALITGVEETFAACTDGDSEAIVVPTLGRGDGGLHRFLLSAASAFVAGVA
Rv2048c|M.tuberculosis_H37Rv        PALITGVEETFAACTDGDSEAIVVPTLGRGDGGLHRFLLSAASAFVAGVA
MMAR_0101|M.marinum_M               --------------------------------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           VNWRGTLDGAGYVELPTYAFDKRRFWLSAEGSGADVSGLGLGASEHPLLG
Rv2048c|M.tuberculosis_H37Rv        VNWRGTLDGAGYVELPTYAFDKRRFWLSAEGSGADVSGLGLGASEHPLLG
MMAR_0101|M.marinum_M               --------------------------------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           AVVDLPASGGVVLTGRLSPNVQPWLADHAVSDVVLFPGTGFVELAIRAGD
Rv2048c|M.tuberculosis_H37Rv        AVVDLPASGGVVLTGRLSPNVQPWLADHAVSDVVLFPGTGFVELAIRAGD
MMAR_0101|M.marinum_M               --------------------------------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          -----------------------------------------------SLP
MSMEG_0408|M.smegmatis_MC2_155      -----------------------------------------------SLP
Mvan_1003|M.vanbaalenii_PYR-1       -----------------------------------------------SLP
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           EVGCSVLDELTLAAPLLLPATGSVAVQVVVDAGRDSNSRGVSIFSRADAQ
Rv2048c|M.tuberculosis_H37Rv        EVGCSVLDELTLAAPLLLPATGSVAVQVVVDAGRDSNSRGVSIFSRADAQ
MMAR_0101|M.marinum_M               ---------------------------------------------MRNNN
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          SGGRMAAVFAAAERVEALTDEYPALSVAAYNGANTVLSGPATDLERAVAG
MSMEG_0408|M.smegmatis_MC2_155      AGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKDLESAVAT
Mvan_1003|M.vanbaalenii_PYR-1       EGGRMAAVFAPADRVESCTVDSPLLSVAAYNGDNTVLSGPAGDLERAVAG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           AGWLLHAEGILRPGSVEPGADLSVWPPAGAVTVDVADGYERLATRGYRYG
Rv2048c|M.tuberculosis_H37Rv        AGWLLHAEGILRPGSVEPGADLSVWPPAGAVTVDVADGYERLATRGYRYG
MMAR_0101|M.marinum_M               LAWLLANQALASEWSASPAYYAPNIVTHAQIHEGAARLGNVFGSRGLRTG
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      -------LLSLLRQRSERYGDKIAFDYCTGEQEHSRLTYQELDIR-----
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LVADGVRCDWLETSHAFHSALLDPILDDFESYARGITFTAPQRILIDNRT
MSMEG_0408|M.smegmatis_MC2_155      LVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRT
Mvan_1003|M.vanbaalenii_PYR-1       FSAAGVRCDWLDTSHAFHSALLDPVLEEFESCADRFEFGTPQRTLVCNRS
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           PAFRGLTAMWARGEEIFAEVRLPEAAGGVGGFGVHPALLDAVLHAVVIAG
Rv2048c|M.tuberculosis_H37Rv        PAFRGLTAMWARGEEIFAEVRLPEAAGGVGGFGVHPALLDAVLHAVVIAG
MMAR_0101|M.marinum_M               ---------------------------------------DRVLLCLPDST
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      ----------------------------ARAIAAHLQDQGVAGERVLVLC
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GAALGRSVTLDAAYWRRHARQPVEFAKSVHTLADMNCKLLVEIGPRPVLT
MSMEG_0408|M.smegmatis_MC2_155      GSALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLT
Mvan_1003|M.vanbaalenii_PYR-1       GEVLSRHARLDGQYWRRHARQPVRFAESVRTLADLGCRLLMEIGPQPVLT
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           DPDELALPFAWQGVSLHATGASAVRARIAPAGPSAVSVELADGLGLPVLS
Rv2048c|M.tuberculosis_H37Rv        DPDELALPFAWQGVSLHATGASAVRARIAPAGPSAVSVELADGLGLPVLS
MMAR_0101|M.marinum_M               DLVQLLLACLARGIVAFISNP---------------ELRPDDHTFQEQDT
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      PSGLDFITAMFGCFYVGAVAVPVHPPVHNRLLSRVASIVADVRATSVLTT
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AAALSAWPDPATSPRVIASLRRTTADQRQITEAVADAYVLGHLPRFAAFR
MSMEG_0408|M.smegmatis_MC2_155      ATALAAWPDPATTPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAFR
Mvan_1003|M.vanbaalenii_PYR-1       AAAMRTWPGTVTAPRVAASMRRKGSDRRQITEALAQAYVAGHRPETAARQ
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           VASMVARPVTERQLLAAVSGSGPDRLFEVIWSPASAATSPGPTPAYQIFE
Rv2048c|M.tuberculosis_H37Rv        VASMVARPVTERQLLAAVSGSGPDRLFEVIWSPASAATSPGPTPAYQIFE
MMAR_0101|M.marinum_M               QPALVVTTDALRDRFARSGIVDPGELWAEANQAKPAAYEPLTGDALAYGT
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      AATRADLKEILDGLHDGDPLRWLAVDTIEADDETSWTPTTVDTDSVAFVQ
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          RDGARVLDLPTYPFEHRQYWFSDSR------EPVAAAPQRGARTETVRLL
MSMEG_0408|M.smegmatis_MC2_155      QPDARKLDLPTYPFEHRQFWFSDNRAIDRDTQTASAGSVTPHRTQAVRLL
Mvan_1003|M.vanbaalenii_PYR-1       HGRGRLLDLPTYPFQHRAYWFPQGQ--------ARTAPTDPVHTETVRFL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           SVAADQDPVAGSYVRSHQALAAVQSWLTDHESGVLVVATRGAMALPREDV
Rv2048c|M.tuberculosis_H37Rv        SVAADQDPVAGSYVRSHQALAAVQSWLTDHESGVLVVATRGAMALPREDV
MMAR_0101|M.marinum_M               YTSGTTGAPKAALHRHGDVWAFIDAMCRN---ALRLTPDDVGLSIARMYF
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      YTSGSTSTPKGVVLTHHNLLANLESISRDAGQGDEARVVSWLPLHHDMGL
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          EDGRIEELAALLGGTVDDPFTFDVLNRLAAQHNQQRSTESIADDRYQIRW
MSMEG_0408|M.smegmatis_MC2_155      EDGQIEELAALIDGETVDEQTLRVLNKLAARHNQQRSTHVDPDARYEIRW
Mvan_1003|M.vanbaalenii_PYR-1       DEERIDELAALLDGPTGSAQTVDVLSKLAARHRQQRGAQSIADARYQIRW
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           ADLAGAAVWGLVRSAQTEHPGRIVLVDSDAATDDAAIAMALATGEPQVVL
Rv2048c|M.tuberculosis_H37Rv        ADLAGAAVWGLVRSAQTEHPGRIVLVDSDAATDDAAIAMALATGEPQVVL
MMAR_0101|M.marinum_M               AYGLGNSVWFPLATGSSAVISRSPLGAESAAN--------LSERFSPSVL
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      IGGIFGVVHFGGTAYLMPPSSFIQRPMSWLEAISWHGANISVGPNFGYQL
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ETAAEPPVGADAADGITWLLVGDDTDATRPLVDVLAARGHRYRILGLPKS
MSMEG_0408|M.smegmatis_MC2_155      DAIASAAASTGAAA--DWILVGDDTAAVLEFADALTAGGHRHQIVALPGS
Mvan_1003|M.vanbaalenii_PYR-1       EKSEAPGAARPTTEATTWLLVTHDSRAAQPIAEVLERRGHPYHIVGLPGS
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           RGGQVYTARVRGSRAADAILVPPGDGPWRLGLGSAGTFENLRLEPVPNAD
Rv2048c|M.tuberculosis_H37Rv        RGGQVYTARVRGSRAADAILVPPGDGPWRLGLGSAGTFENLRLEPVPNAD
MMAR_0101|M.marinum_M               YGVPTFLARVADTCAADAFR---------------------SLRCVVSAG
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      CVERSTPEERATLDLSTWVRAYCGAEPVRAATMRRFTEAFAPAGFRADAF
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GAEEHELADTLRD-------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      DADEAQLVDTLR--------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       DADAAPAEEALR--------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           APLGPGQVRVAMRAIAANFRDIMITLGMFTHDALLGGEGAGVVVEVGPGV
Rv2048c|M.tuberculosis_H37Rv        APLGPGQVRVAMRAIAANFRDIMITLGMFTHDALLGGEGAGVVVEVGPGV
MMAR_0101|M.marinum_M               EALELGLAQRLMKFFGG---------------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      HPVYG---------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------AAADATDLRIVHVAALDAAESDTS
MSMEG_0408|M.smegmatis_MC2_155      ---------------------------AASAGELYVVHIAAGDGAAAP--
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------ATVSQPRPHILYLAALEEPGGS-A
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           TEFSVGDSVFGFFPDGSGTLVAGDVRLLLPMPADWSYAEAAAISAVFTTA
Rv2048c|M.tuberculosis_H37Rv        TEFSVGDSVFGFFPDGSGTLVAGDVRLLLPMPADWSYAEAAAISAVFTTA
MMAR_0101|M.marinum_M               ----------------------------IPLLDGIGSTEVGQTFISSTVD
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      -----------------------------------LAEATLFVSGRPENV
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          MKSLLRMQHRVLGGTRRLFGAAVAAQLRSPMWLVTRGAQHVTDTDVVAPD
MSMEG_0408|M.smegmatis_MC2_155      MRDLLRVQHRTLGGLRRLFRAANDAELRSPIWLVTRDGQRVTDTDTVVPE
Mvan_1003|M.vanbaalenii_PYR-1       AETLGWMQHRVLAAARRLFQLAATAGARAPIWLITAGAQRITGDETVEPA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           YYAFIHLADVQPGQRVLIHAGTGGVGMAAVQLARHLGLEVFATASKGKWD
Rv2048c|M.tuberculosis_H37Rv        YYAFIHLADVQPGQRVLIHAGTGGVGMAAVQLARHLGLEVFATASKGKWD
MMAR_0101|M.marinum_M               EWRLGTLGKVLSPYEIRVVAPDG---------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      LPTVRSLDNAALREHRVVPAAADDANAAAVVGCGPAAYGEEIVIVDPATR
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          QTCLWGFGRAASLEHPQIWGGLADLGGGTSDEWSRLLNRIAATHDP----
MSMEG_0408|M.smegmatis_MC2_155      QSCLWGFGRAAALELPHIWGGLADLSG-ADTEWPRLIARITSPRD-----
Mvan_1003|M.vanbaalenii_PYR-1       QTSLWGFGRAAALEQPELWGGLADVTTGDAEEWSALIDHIVAAPT-----
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           TLRAMGFDDDHISDSRSLEFEDKFRAATGGRGFDVVLDSLAGEFVDASLR
Rv2048c|M.tuberculosis_H37Rv        TLRAMGFDDDHISDSRSLEFEDKFRAATGGRGFDVVLDSLAGEFVDASLR
MMAR_0101|M.marinum_M               TTAAPGVEGDLWVRGPSLTAGYWNRPTQPPSISDSWLDTRDRVCVDAHG-
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      REFPPDVVGEIWVAGENVAQGYLGKPSESAETFAAHLADSG---------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           LVAPGGVFLEMGKTDIRDPGVIAQQYPGVRYRAFDLFEAGPDRIAQILAE
Rv2048c|M.tuberculosis_H37Rv        LVAPGGVFLEMGKTDIRDPGVIAQQYPGVRYRAFDLFEPGRPRMHQYMLE
MMAR_0101|M.marinum_M               --------------------------------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          -------------AVMEDQVAVRGSTSYVPRLVHRDTLPSGKPLHLRADA
MSMEG_0408|M.smegmatis_MC2_155      ---------------GEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDR
Mvan_1003|M.vanbaalenii_PYR-1       ---------------SEDQIAVRGREIHVARLTRCAEKANAAALELRREA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           LATLFGDGVLRPLPVTTFDVRRAPAALRYLSQARHTGKVVMLMPGSWAAG
Rv2048c|M.tuberculosis_H37Rv        LATLFGDGVLRPLPVTTFDVRRAPAALRYLSQARHTGKVVMLMPGSWAAG
MMAR_0101|M.marinum_M               -----------------------------------------WVTYRCRAD
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      ----------------------------------RGPFLRTGDYGFLLDG
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          TYLVTGGLGSLGLEIAGYLAANGAGHLVLTSRRTPDEAAASRIEALRERH
MSMEG_0408|M.smegmatis_MC2_155      TYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPGDDARRRLDGLREQY
Mvan_1003|M.vanbaalenii_PYR-1       TYLVTGGLGALGLEVAEFLASHGAGHLVLTGRRSASDTVRQRIDAMRERF
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           TVLITGGTGMAGSAVARHVVARHGVRNLVLVSRRGPDAPGAAELVAELAA
Rv2048c|M.tuberculosis_H37Rv        TVLITGGTGMAGSAVARHVVARHGVRNLVLVSRRGPDAPGAAELVAELAA
MMAR_0101|M.marinum_M               DIEIVGGININPREIEQLIVEDHLVAETAVVAVREATG------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      ELFVTGRLKDLIIIRGRNYHPNDIEATVQEVHPALMSGRGAAFAVSPDPS
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GCEVRVVTADVADAHAVARLLATVQAEMPPLAGIVHAAGEIGTTPLADLD
MSMEG_0408|M.smegmatis_MC2_155      ACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLD
Mvan_1003|M.vanbaalenii_PYR-1       DCQVLVATADVADRDDVARLFSTMRSELPPLAGIVHAAGEIGTSPLRTLD
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           AGAQVQVVACDAADRAALAKVIADIPVQHPLSGVIHTAGALDDAVVMSLT
Rv2048c|M.tuberculosis_H37Rv        AGAQVQVVACDAADRAALAKVIADIPVQHPLSGVIHTAGALDDAVVMSLT
MMAR_0101|M.marinum_M               -------------ESALQAFLVPESGASLGESAIKELHRRLLGSLSPHKV
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      GTEQLVIVQEVDRGRLGEVDTDELIAAIR---TAVTSQHDIGVHTVVLVD
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          DAEVDRVFAGKVWGAWHLSEATSDLQ--LDFFISTSSIASVWGGFGQAAY
MSMEG_0408|M.smegmatis_MC2_155      DAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAY
Mvan_1003|M.vanbaalenii_PYR-1       DAEMDRVFAGKVWGAVYLCEEVADMG--LDFFLATSSIASVWGSHGQTAY
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           PDRVDVVLRSKVDAAWHLHELTRDLDVSAFVMFSSMAGLVGSSGQANYAA
Rv2048c|M.tuberculosis_H37Rv        PDRVDVVLRSKVDAAWHLHELTRDLDVSAFVMFSSMAGLVGSSGQANYAA
MMAR_0101|M.marinum_M               PHRFEIAERLPRTASGKLQRGQ----------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      PLRIPTTSSGKIR-------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GAANAFLDGLAWRLREQGVAGVSVNFGPWSAGMADAQSRARLEQRGIKTL
MSMEG_0408|M.smegmatis_MC2_155      GAANAFLDGLAWRLRERGVTAVSVNFGPWAAGMADAESRARLEQRGVRTL
Mvan_1003|M.vanbaalenii_PYR-1       GAANAFLDGLADSLRARGIPGISVNFGPWAAGMADAKAREQLSRRGVKTL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           ANSFLDALAAHRRAHGLPAISLGWGLWDQASAMTSGLDAADLARLGREGV
Rv2048c|M.tuberculosis_H37Rv        ANSFLDALAAHRRAHGLPAISLGWGLWDQASAMTGGLDAADLARLGREGV
MMAR_0101|M.marinum_M               --------------------------------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          SPADALAGLSDAVISAAPHPVVARVDWSRFLPLYQQAGRRGFLAELEREL
MSMEG_0408|M.smegmatis_MC2_155      SPAEALAGMADVVAGPVQG-VVAKIDWSRFLPLYQQAGRRAFLSELESEL
Mvan_1003|M.vanbaalenii_PYR-1       APADALAGMADVIAASTAHAVVARIDWATFLPVYQLQRRRAFLSQLEREV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           LALSTAEALELFDTAMIVDEPFLAPARIDLTALRAHAVAVPPMFSDLASA
Rv2048c|M.tuberculosis_H37Rv        LALSTAEALELFDTAMIVDEPFLAPARIDLTALRAHAVAVPPMFSDLASA
MMAR_0101|M.marinum_M               -------------------------LRTQPAAQPVWERRCTVGTSDSDGQ
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      ---------------------------RRTCRQRFLDGELDAFAEWRLAT
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          PAAPAQQGPAVTASGRTPLVERLTTAPLQQRKRLLTDYLRDAVAEVTR-V
MSMEG_0408|M.smegmatis_MC2_155      PAAATGAAAPATVPGKPPLVEQLTKAPVQQRKSLITNYLRNAVAEVTR-V
Mvan_1003|M.vanbaalenii_PYR-1       PDVPDASAPAP--SGTTRFVEELTLAPVEQRRKLVLEYLRAAVAEVTR-V
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Mb2074c|M.bovis_AF2122/97           PTRRQVDDSVAAAKSKSALAHRLHGLPEAEQHAVLLGLVRLHIATVLGNI
Rv2048c|M.tuberculosis_H37Rv        PTRRQVDDSVAAAKSKSALAHRLHGLPEAEQHAVLLGLVRLHIATVLGNI
MMAR_0101|M.marinum_M               RDPQTQTNYKVGPRVGPVTLDERLAVLQQEGHRLIADTVSAEVAQILGDP
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      PRPAQPVPAADEQADEQAGAGPGAGPGADEIRAWFVAQLAGELG-----L
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          DAAEIREDAGFFDLGMDSLMAVELRRRIETGVGKEIPVTLVMDHPRLSDA
MSMEG_0408|M.smegmatis_MC2_155      DADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDA
Mvan_1003|M.vanbaalenii_PYR-1       DAAEIRDEAGFFDLGMDSLMAIELRRRLEQGLGKELPVTLAMDHPHLSDA
MLBr_00135|M.leprae_Br4923          -----------------------------------MTASVEGADQKSEKL
MUL_2005|M.ulcerans_Agy99           -----------------------------------MTTSGESADQQNDKL
MAV_3108|M.avium_104                -----------------------------------MPG--------TEQH
Mb2074c|M.bovis_AF2122/97           TPEAIDPDKAFQDLGFDSLTAVEMRNRLKSATGLSLSPTLIFDYPTPNRL
Rv2048c|M.tuberculosis_H37Rv        TPEAIDPDKAFQDLGFDSLTAVEMRNRLKSATGLSLSPTLIFDYPTPNRL
MMAR_0101|M.marinum_M               AAERIDRDVAFAELGFDSRMTVELRNRLAAVTGLRLPETVGWDYGSISRL
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      SPDDIDTGQPFAYYGLDSVRAIQLMTALEAWSGIKVAPTLAYDHPTIDLA
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ADYLLGDVLGLTEAATAP---------KAATVVSTAADEPIAIVAVSCRF
MSMEG_0408|M.smegmatis_MC2_155      ADYLLVEVLGLGEQTNVR---------QASTVT-ARTDDPIAVVAVSCRF
Mvan_1003|M.vanbaalenii_PYR-1       AEYVLGDVLGLSEHT-VA---------QPDTPSTVRTDDPIAIVGMACRF
MLBr_00135|M.leprae_Br4923          ISYLKKVVVELDETR------------ARLREYEQRATEPVAVVGIGCRF
MUL_2005|M.ulcerans_Agy99           FRYLKKVAVELDEAR------------ARLREYEQRATEPVAVVGIGCRF
MAV_3108|M.avium_104                LDYLKRLTADLRRTR------------RRVAELEGRLSEPVAVVGMACRY
Mb2074c|M.bovis_AF2122/97           ASYIRTELAGLPQEI------------KHTPAVRTTSEDPIAIVGMACRY
Rv2048c|M.tuberculosis_H37Rv        ASYIRTELAGLPQEI------------KHTPAVRTTSEDPIAIVGMACRY
MMAR_0101|M.marinum_M               AAHLETELAGSGGRG------------KPGPSVAGG--APVAIVGVGCRY
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------MEIDVTGIACRF
TH_4458|M.thermoresistible__bu      AEHLAGLTHTATSTAADAGVSTGAGRRPEHGPAPDRADEPIAIIGIGCRF
                                                                            : : .:.**:

Mflv_0405|M.gilvum_PYR-GCK          PG-APNPEAFWDLLSGGVDAIREVPEDR-FDIDEFYDPDPDAAGKTYTRY
MSMEG_0408|M.smegmatis_MC2_155      PG-APDPESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRF
Mvan_1003|M.vanbaalenii_PYR-1       PG-ADDTDAFWSVLAEGADLIREIPDDR-FDINEFYDPDPEAAGKIYSRY
MLBr_00135|M.leprae_Br4923          PGGVDSPDRLWDVVSECRDVVSEFPTDRGWDVDGLFDPDPDAEGKTYTRW
MUL_2005|M.ulcerans_Agy99           PGGADGPEGLWDLVSQGRDAVTEFPNDRGWDTEGLFDPDPDAEGKTYTRW
MAV_3108|M.avium_104                AGGVDSPEALWDLVIEGRDTVSDFPVDRGWDVEGLYDPDPDAKGKMYTRQ
Mb2074c|M.bovis_AF2122/97           PGGVNSPDDMWDMLIQGRDVLSEFPADRGWDLAGLYNPDPDAAGACYTRT
Rv2048c|M.tuberculosis_H37Rv        PGGVNSPDDMWDMLIQGRDVLSEFPADRGWDLAGLYNPDPDAAGACYTRT
MMAR_0101|M.marinum_M               PGGVESAGGLWDVVVGGRDVISGFPVDRGWDVEGVFDPDPDALGKTYCRL
MAB_3575c|M.abscessus_ATCC_199      PG-ADGVEAFWDMLLRGRNGTRVVPEDRWWADDFVSPAPPYGTGKVNTRH
TH_4458|M.thermoresistible__bu      PG-ADGPAAYWRLLREGRDAITATPPER-WDTDSVGDG---------TRW
                                    .* . .    * ::    :     * :* :    .             * 

Mflv_0405|M.gilvum_PYR-GCK          GGFLDHIDEFDPEFFGLSPREAVWIEPQQRLMLETVWEGLERAGYAPSAL
MSMEG_0408|M.smegmatis_MC2_155      GGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDL
Mvan_1003|M.vanbaalenii_PYR-1       GGFLDGVDGFDPEFFGISPREAVWIDPQQRLVLETAWEGLERAGYSAAAL
MLBr_00135|M.leprae_Br4923          GAFLDDAAGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEYAGIDPLSL
MUL_2005|M.ulcerans_Agy99           GAFVENATNFDAGFFGIPPSEVLAMDPQQRLMLEVSWEALEHAGIDPMSL
MAV_3108|M.avium_104                GSFLQHAGDFDAGFFGIGPSEALAMDPQQRIMLEICWEALERAGIDPSAL
Mb2074c|M.bovis_AF2122/97           GGFVDGVGDFDPAFFGVGPSEALAMDPQQRMLLELSWEALERAGIDPTGL
Rv2048c|M.tuberculosis_H37Rv        GGFVDGVGDFDPAFFGVGPSEALAMDPQHRMLLELSWEALERAGIDPTGL
MMAR_0101|M.marinum_M               GGFLDGADRFDAGFFGIGPSEALAMDPQQRLLLECSWEALEDAGIDPVSL
MAB_3575c|M.abscessus_ATCC_199      GAFIDDPERFDHGFFGIAPSEAAATDIQQRLVLQAGYHALEDAGIDPQSL
TH_4458|M.thermoresistible__bu      GGFLERIDGFDAGFFGISPREAVRIDPQQRLLLEVAWEALEDAGLVPDRL
                                    *.*::    **  ***: * *.   : *:*::*:  :..** **  .  *

Mflv_0405|M.gilvum_PYR-GCK          RGSRTGVFVGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALG
MSMEG_0408|M.smegmatis_MC2_155      RGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALG
Mvan_1003|M.vanbaalenii_PYR-1       RGSRSGVYVGVGANEYSHLLSGGSLDGIEAQFITGNALNVIAGRVSFTLG
MLBr_00135|M.leprae_Br4923          RGSATGVFTGIFAPSYGS----RDTGGLQGYGLTGTAVSVASGRVSYVLG
MUL_2005|M.ulcerans_Agy99           RGSSTGVFTGIFAPSYGG----KDVGALQGYGLTGSPVSVASGRVAYVLG
MAV_3108|M.avium_104                RGTATGVFAGVIHAGYGG----EVKGELEGYGLTGSTLSVTSGRVSYVLG
Mb2074c|M.bovis_AF2122/97           RGSATGVFAGVMTQGYGM----FAAEPVEGFRLTGQLSSVASGRVAYVLG
Rv2048c|M.tuberculosis_H37Rv        RGSATGVFAGVMTQGYGM----FAAEPVEGFRLTGQLSSVASGRVAYVLG
MMAR_0101|M.marinum_M               RGSVTGVFTGLMSSDYGAG---RVSGDLEGYGLTSAAASVASGRVAYLLG
MAB_3575c|M.abscessus_ATCC_199      RGSTTGVFVGVMSSDWGALHL-TDYAGMTPQRGVGNGYCMLANRVSYALD
TH_4458|M.thermoresistible__bu      AGSRTGVFTGVSTYDYLHLQ-LSHPELIDAYSGTGTASSIAANRLSYVFD
                                     *: :**:.*:    :           :     ..      :.*::: :.

Mflv_0405|M.gilvum_PYR-GCK          LEGPAVAVDTACSSSLVAVHQATQALRSGDCDMALAGGVNVLLSPVTVVA
MSMEG_0408|M.smegmatis_MC2_155      FEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVA
Mvan_1003|M.vanbaalenii_PYR-1       LEGPAVAVDTACSSSLVAVHQACQGLQSGDCDLALAGGVNVLLSPATTIA
MLBr_00135|M.leprae_Br4923          LEGPAVSVDTACSSSLVAIHWAMSSLRSGECDLALAGGVTVMGLPSIFVG
MUL_2005|M.ulcerans_Agy99           LEGPALSVDTACSSSLVAIHWAMASLRSGECDMALAGGVTVMGLPSIFVG
MAV_3108|M.avium_104                LEGPAVSVDTACSSSLVAMHLAAQSLRSGECDLALAGGVTVMATPAAFVE
Mb2074c|M.bovis_AF2122/97           LEGPAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPDIFVE
Rv2048c|M.tuberculosis_H37Rv        LEGPAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPDIFVE
MMAR_0101|M.marinum_M               LEGPAVSVDTACSSSLVALHLAASSLRSGECDVALAGGVTVMATPATFVG
MAB_3575c|M.abscessus_ATCC_199      LTGPSMSVDTACSSSLTAVHLAAGALRAGECDLAIVAGVNLMLTPILSIF
TH_4458|M.thermoresistible__bu      FRGPSLTLDSACSSSLVAVHQACRSLRDGECDLALAGGVNIMLSAGIGLN
                                    : **::::*:****:*.*:* *  .*: *:**:*:..**.:   .   : 

Mflv_0405|M.gilvum_PYR-GCK          ASRARMLSPVGRCKTFDASADGYVRSEGCGILVLKRLSDAVRDGDRVCAV
MSMEG_0408|M.smegmatis_MC2_155      ASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAV
Mvan_1003|M.vanbaalenii_PYR-1       TSRARMLSPDGRCKTFDAAADGYVRGEGCGILVLKRLSDAVRDGDRIQAV
MLBr_00135|M.leprae_Br4923          FSRQRGLAADGRCKAFARAADGTGWGEGAGVVVLERLSDAQRLGHTVLAV
MUL_2005|M.ulcerans_Agy99           FSRQRGLAADGRCKAFAAAADGTGWGEGAGVLVLERLSDAQRNGHNVLAV
MAV_3108|M.avium_104                FSRQRALAPDGRCKVYAGAADGTSWSEGAGVLVLERLADARRLGHPVWAV
Mb2074c|M.bovis_AF2122/97           FSRWRGLSPDGRCKAFAAAADGTGFSEGGGMLVLQRLSDARRLGHPVLAV
Rv2048c|M.tuberculosis_H37Rv        FSRWRGLSPDGRCKAFAAAADGTGFSEGGGMLVLQRLSDARRLGHPVLAV
MMAR_0101|M.marinum_M               FSRQRGLAADGRCKAFAGAADGTGFSEGAGVVVLMRLSEARRRGLAVLGV
MAB_3575c|M.abscessus_ATCC_199      YTQAGLSAPDGRCRPFAKSGGGIGRGEGVGAVVLRRSEDRPDDAPAPYAT
TH_4458|M.thermoresistible__bu      FTRAGVMATDGRCKTFDARADGWVRGEGAGIVVLKPLREALADEDPIYAV
                                     ::    :. ***: :   ..*   .** * :**    :         ..

Mflv_0405|M.gilvum_PYR-GCK          IAGSAVNQDGASSGLTVPNGGAQQRLIGTVLARAGITGGEVDYLEAHGTG
MSMEG_0408|M.smegmatis_MC2_155      IPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTG
Mvan_1003|M.vanbaalenii_PYR-1       IRGSAVNQDGASGGLTVPNGGAQQRVIAAALTRAGLSGSDIDYLEAHGTG
MLBr_00135|M.leprae_Br4923          VRGSAVNQDGASNGLTAPNGLAQQRVIQAALTNAGLSSADVDVVEAHGTA
MUL_2005|M.ulcerans_Agy99           VRGSAINQDGASNGLTAPNGLTQQRVIQAALANCGLTSADVDVVEAHGTA
MAV_3108|M.avium_104                LRGSAVNQDGASNGLTAPNGPSQQRVIRAALANAGLSAVDVDVVEGHGTG
Mb2074c|M.bovis_AF2122/97           VVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTG
Rv2048c|M.tuberculosis_H37Rv        VVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTG
MMAR_0101|M.marinum_M               IAGSAVNQDGASNGLTAPNGPAQQRVIEAALANAGLTAADVDVVEGHGTG
MAB_3575c|M.abscessus_ATCC_199      VRGSFVGQDGRSNGITAPTRRGQERVIAAALRSAGHTGADLHFVEAHGTG
TH_4458|M.thermoresistible__bu      IRGSAVNQDGRTNGLMAPSRTAQEVVLTDAYRRAGVSPGVVQYVEAQGIG
                                    : .* :.*** :.*: .*.   *: ::  .   .* :   :. :*.:* .

Mflv_0405|M.gilvum_PYR-GCK          TPLGDPIEVQAAAAAYAGAR-DADRPLLMGSVKTNIGHTESASGAAGLIK
MSMEG_0408|M.smegmatis_MC2_155      TPLGDPIEVQAAAAAYGAGR-DADRPLLMGSVKTNIGHTESASGAAGLIK
Mvan_1003|M.vanbaalenii_PYR-1       TSLGDPIEVQAAGAVLGAGR-DPDRPLLMGSVKTNVGHLESASGVAGLIK
MLBr_00135|M.leprae_Br4923          TTLGDPIEAQALLATYGQGR-PADQPLWVGSIKSNMGHTQAAAGVAGVIK
MUL_2005|M.ulcerans_Agy99           TTLGDPIEAEALLATYGQGR-PTDQPLWVGSIKSNMGHTQAAAGVAGVIK
MAV_3108|M.avium_104                TVLGDPIEAQALLATYGQDR-PADRPLWLGSIKSNIGHTSAAAGVAGVIK
Mb2074c|M.bovis_AF2122/97           TTLGDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAGVIK
Rv2048c|M.tuberculosis_H37Rv        TTLGDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAGVIK
MMAR_0101|M.marinum_M               TTLGDPIEAQALLATYGQAR-PADQPLWLGSIKSNMGHTQAAAGIAGVIK
MAB_3575c|M.abscessus_ATCC_199      TTLGDLIETQALGATCGDRV--GRAPLVVGSVKGNIGHTEGAAGIAGFIK
TH_4458|M.thermoresistible__bu      TPVGDAIEVGALGTVLAEDR-PPDSPCLIGSVKTNIGHLEAAAGIAGLIK
                                    * :** **. *  :. .        *  :**:* *:** ..*:* **.**

Mflv_0405|M.gilvum_PYR-GCK          VVLSLQHETLPQSLHFDTPSPHIPWDSLPVRVVDTAMPWQPN-GRPRRAG
MSMEG_0408|M.smegmatis_MC2_155      VVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTN-GRVRRAG
Mvan_1003|M.vanbaalenii_PYR-1       VVLSLQHEMLPRHLHFKTPSPHIPWDRLAVRVVAEPTPWRAD-GRPRRAG
MLBr_00135|M.leprae_Br4923          MVQAMRHHVMPATLHVDEPSPRVDWTTGAVSVLTEARDWSVE-GRPRRAG
MUL_2005|M.ulcerans_Agy99           MVQAMRHGLMPASLHVDEPSKRVDWESGAVSVLAEARDWPDA-GRPRRAG
MAV_3108|M.avium_104                MVQALRHGVMPKTMHVDVPSPHVDWSAGAVSLLTDPRPWPEH-GGPRRAG
Mb2074c|M.bovis_AF2122/97           MVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWPAG-ARTRRAG
Rv2048c|M.tuberculosis_H37Rv        MVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWPAG-ARTRRAG
MMAR_0101|M.marinum_M               MVQAMRHELMPATLHVDVPSPHVDWSSGAVSLLTQPRPWPAVDGRPRRAG
MAB_3575c|M.abscessus_ATCC_199      ACLSMHHRTVPPSLFADDENPALDLAERNLKLAVSAEKLPRG---DLLAG
TH_4458|M.thermoresistible__bu      VALALRHRMIPPTLNFTEPNPTIEFDKLPVRVAQTLTPWPDD-SGRAVAG
                                       :::*  :*  :     .  :      : :                **

Mflv_0405|M.gilvum_PYR-GCK          VSSFGFTGTNAHVLIEEAPTDLAGPTEPTAPAEPVDEDAAADP-APAPVE
MSMEG_0408|M.smegmatis_MC2_155      VSSFGFTGTNAHVLVEEAPPQLH-----TADAAPVEPAATAEAGTDDSPQ
Mvan_1003|M.vanbaalenii_PYR-1       VSSFGFSGTNAHVVLEEPPAQSADLRQPPTDGK-DGAAGLESATAPEPAG
MLBr_00135|M.leprae_Br4923          VSSFGISGTNAHVILEEAPTPVE-----------ASYSTAD--QQRLSVV
MUL_2005|M.ulcerans_Agy99           VSSFGISGTNAHVILEEAPAPEA-----------VPDSESNKGEPSLPVV
MAV_3108|M.avium_104                VSSFGISGTNAHVIVEQAPAAAE-----------TEAAPAS-STMPDAVV
Mb2074c|M.bovis_AF2122/97           VSSFGISGTNAHVIIEAVPVVPR-----------REAGWAG------PVV
Rv2048c|M.tuberculosis_H37Rv        VSSFGISGTNAHVIIEAVPVVPR-----------REAGWAG------PVV
MMAR_0101|M.marinum_M               VSSFGISGTNAHVIVEQVCPEVV-----------AEAVDVS-----PDSL
MAB_3575c|M.abscessus_ATCC_199      VSSFGLGGTNVHVVIGSAPRVRR-----------PIRRGG--------IG
TH_4458|M.thermoresistible__bu      VSAFGFGGTNAHVVLAEAPQVRA--------------AATADDHADGFVE
                                    **:**: ***.**::                                   

Mflv_0405|M.gilvum_PYR-GCK          VLPLSARSPEALVALAQRYETWLTAHPEADLADVCRTAGTGRSHFEHRAA
MSMEG_0408|M.smegmatis_MC2_155      VLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAA
Mvan_1003|M.vanbaalenii_PYR-1       VLPISARSPEALTALARRYESWLTAHPDADIADVCYTAGAGRSHFEHRAA
MLBr_00135|M.leprae_Br4923          PWVVSGRSTAALMAQASRLAFYVQADPEVDPVDVGCALAA-RSVFEHRAV
MUL_2005|M.ulcerans_Agy99           PWVISARSAEALTAQAGRLLAHVQADPQSNPVDIGFSLAG-RSAFEHRAV
MAV_3108|M.avium_104                PWVVSARSAEALAGQARRLLDHVTADAQASPLDVGWSLVSTRAVFEHRAV
Mb2074c|M.bovis_AF2122/97           PWVVSAKSESALRGQAARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRAV
Rv2048c|M.tuberculosis_H37Rv        PWVVSAKSESALRGQAARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRAV
MMAR_0101|M.marinum_M               PWVVSGKSEAAVAAQAKRLLAAVQADEGLDRLDVGFSLAR-RTAFEYRAV
MAB_3575c|M.abscessus_ATCC_199      VLTVSGNDAAALRRNLDRLVAGFDPTEHWP--RYCYSTNQVKAGGTQRIA
TH_4458|M.thermoresistible__bu      ILPLSARSQAALDALAERYESALTG--GVPPADLCHTAGARRAHHDHRLA
                                       :*...  *:     *    .             :    ::    * .

Mflv_0405|M.gilvum_PYR-GCK          LVVDSVESARIALTDLAQNRLRPGVVRG--EHLNHPTTAWMFTGQGSQYP
MSMEG_0408|M.smegmatis_MC2_155      LVVDSVERAREGLAALAEGRTPAGVVRG--EHVHRPTTAWLFTGQGSQYP
Mvan_1003|M.vanbaalenii_PYR-1       LVVDSVDGARDLLAGLAEDRLGPGAVRG--VCGDPPKTAWLFTGQGSQYP
MLBr_00135|M.leprae_Br4923          VVGESREQLIAGLAGLAVGESGAGVAIG--QAAPLGKTVVVFPGQGAQRI
MUL_2005|M.ulcerans_Agy99           VVGADRQQLLTGLATLADGAPGAGVVTG--QAGSVGKTAVVFPGQGSQRI
MAV_3108|M.avium_104                VVGRERGALATGLAGLASGRPGPATVVG--RARSTGKTVLVFPGQGSQTL
Mb2074c|M.bovis_AF2122/97           VVGGDRDRLLAGLDELAGDQLGGSVVRG--TATAAGKTVFVFPGQGSQWL
Rv2048c|M.tuberculosis_H37Rv        VVGGDRDRLLAGLDELAGDQLGGSVVRG--TATAAGKTVFVFPGQGSQWL
MMAR_0101|M.marinum_M               VLGEDRQQLISGLTELAAGQPGPTVLNG--RAATVSKTVMVFPGQGSQRL
MAB_3575c|M.abscessus_ATCC_199      LVTRDG-ADLAGEAEVALHRLARRNERA--RRRRP-RIAFVYTGQGSQYR
TH_4458|M.thermoresistible__bu      VVGASRAELIGALAAYRRGEPHPGVFTGRSQSGHRSGVVFVFSDEGSQWR
                                    ::  .                      .          . ::..:*:*  

Mflv_0405|M.gilvum_PYR-GCK          GMARELFDTEPVFADTVTRCADAVADLLPRPLLDVMFAGGREAGVPPTET
MSMEG_0408|M.smegmatis_MC2_155      GMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRET----ADL
Mvan_1003|M.vanbaalenii_PYR-1       GMARELFDTEPVFRDTVTRCAEAIGDTLPRPLLEVLFDTDGDN----GQT
MLBr_00135|M.leprae_Br4923          GMGRELCSQLPVFAEEFDAVTGELDRHMRLPLRDVVWGADAGL-------
MUL_2005|M.ulcerans_Agy99           GMARELHDQLPVFAEAFDAVADELDRHLRIPLCEVMWGSDVAL-------
MAV_3108|M.avium_104                GMGRQLYERFEVFAGALDEAVAVVDEHSRLSVREVMWGADPEL-------
Mb2074c|M.bovis_AF2122/97           GMGMGLHAGYPVFAEAFNTVVGELDRHLLRPLREVMWGHDENL-------
Rv2048c|M.tuberculosis_H37Rv        GMGMGLHAGYPVFAEAFNTVVGELDRHLLRPLREVMWGHDENL-------
MMAR_0101|M.marinum_M               GMGQQLHGQFPVFAQAFDAVVEQLDRYLRLPLRDALWGGDEHL-------
MAB_3575c|M.abscessus_ATCC_199      EMGLALREQHSGFAEALAEADALLEPHFGGSVVRAIETGEDHLG----RS
TH_4458|M.thermoresistible__bu      GMAQRLYAEDQVFRTALAECDRALRRHMEISPLSELLADPSHSR------
                                     *.  *      *   .      :      .    :              

Mflv_0405|M.gilvum_PYR-GCK          LRHTSFAQPALFAVEMGLARLWQSWGIVPDVVLGHSVGQYAAACVAGVFS
MSMEG_0408|M.smegmatis_MC2_155      LQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFS
Mvan_1003|M.vanbaalenii_PYR-1       LRHTSYAQPALFAIEMGLARLWQARGIEPDVVLGHSVGQYAAACVAGVFG
MLBr_00135|M.leprae_Br4923          LDSTEFAQPALFAVEVALFAVLQHWGLQPDFVMGHSIGELAAAYVAGVLA
MUL_2005|M.ulcerans_Agy99           LDSTEFAQAALFAVEVALFAALQRWGLQPDFVMGHSVGELSAAYVAGVLT
MAV_3108|M.avium_104                LQSTEFAQPALFVFEVALAALWESLGVTPDVVMGHSVGEIAAACVAGVLS
Mb2074c|M.bovis_AF2122/97           LNSTEFAQPALFAVEVALFRLLGSWGVRPDFVMGHSIGELSAAHVAGVLS
Rv2048c|M.tuberculosis_H37Rv        LNSTEFAQPALFAVEVALFRLLGSWGVRPDFVMGHSIGELSAAHVAGVLS
MMAR_0101|M.marinum_M               LESTEFAQPSLFAVEVALFALLRDWGVSPDVVMGHSVGELSAAHVAGVLT
MAB_3575c|M.abscessus_ATCC_199      LDDTVVAQPALFALQYALTTTFAAHGVRPDVVLGHSVGEIAACAAAGVLD
TH_4458|M.thermoresistible__bu      MDEVTIASPALFAVQVALAALWQSWGVEPAAVIGHRMGEVAAAHVAGVLG
                                    :  .  *..:**..: .*       .: *  *:** :*: :*. .***: 

Mflv_0405|M.gilvum_PYR-GCK          LEDGARLMAERGRLFGSLPEGGRMVAVFADAKRVEQVAADFPRVSVGAYN
MSMEG_0408|M.smegmatis_MC2_155      LDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYN
Mvan_1003|M.vanbaalenii_PYR-1       LEDGARLVADRGRLFGGLPVGGRMVAVFTDAEVVEDFADEFPQVSVAAYN
MLBr_00135|M.leprae_Br4923          PADAAMLVVARGRLMQSMPAGGTMWAVAASEDEVVSLLGEG--VGIAAIN
MUL_2005|M.ulcerans_Agy99           LVDAAMLVVARGRLMQALPAGGAMVAVAAAEDEVLPSLTDG--VGIAAIN
MAV_3108|M.avium_104                LRDAARLVAARGALMAALPPGGVMVAVTAGESQVGPLLGGG--VSIAAVN
Mb2074c|M.bovis_AF2122/97           LENAAVLVAARGRLMQALPAGGAMVAVQAAEEEVRPLLSAE--VDIAAVN
Rv2048c|M.tuberculosis_H37Rv        LENAAVLVAARGRLMQALPAGGAMVAVQAAEEEVRPLLSAE--VDIAAVN
MMAR_0101|M.marinum_M               LDDAAKLVAARGRLMQALPEGGAMFAIAASEHEVSPLLGEA--VGIAAIN
MAB_3575c|M.abscessus_ATCC_199      PAAAAALVVTRGALMGALPAGGTMLAARLPAELADEFVSGP--VALAAVN
TH_4458|M.thermoresistible__bu      LDDAAALLCGRTRLSRLASTG-----------------------------
                                       .* *:  *  :    . *                             

Mflv_0405|M.gilvum_PYR-GCK          GPN-TVLSGPGEDLEQIVGTFGEDGIRCTWLETSHAFHSELLDPVLDEFE
MSMEG_0408|M.smegmatis_MC2_155      GPN-TVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDEFE
Mvan_1003|M.vanbaalenii_PYR-1       GPN-TVLAGPASDLEQIVAGCSGEGIRTTWLDTSHAFHSALLDPVLDEFE
MLBr_00135|M.leprae_Br4923          APESVVISGPQAAVSAIADKFAAQGRRVHQLAVSHAFHSPLMEPMLEEFV
MUL_2005|M.ulcerans_Agy99           APKSVVISGAEAAVTAISDQFAQQGRRVHRLAVSHAFHSPLMEPMLEEFA
MAV_3108|M.avium_104                GPDAVVLSGEQEAVAAVADRLAGSGARVHRLAVSHAFHSALMEPMLDGFA
Mb2074c|M.bovis_AF2122/97           GPASLVISGAQNAVAAVADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFA
Rv2048c|M.tuberculosis_H37Rv        GPASLVISGAQNAVAAVADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFA
MMAR_0101|M.marinum_M               APDAVVISGERAAVGVLAEELIDRGRRVHRLAVSHAFHSPLMEPMLADFA
MAB_3575c|M.abscessus_ATCC_199      GPDSVTFSGPVERIAEVADQLNGRGVHTRELVVSHAFHSPAMEPVGGELA
TH_4458|M.thermoresistible__bu      -------------------------------------------AVREGLD
                                                                               .:   : 

Mflv_0405|M.gilvum_PYR-GCK          SYAAQLQFAAPTLPLVCNRTGAVLTGQT-SLDAQYWRRHSRQPVQFAESV
MSMEG_0408|M.smegmatis_MC2_155      AYAAQFQFAAPTLPLVCNRTGAVLTGQT-PLDAQYWRRHSRQPVQFAESV
Mvan_1003|M.vanbaalenii_PYR-1       SCAARLAYAAPTRPLVCNRTGAVVTGPG-VIDAQYWRRHARQPVQFAESV
MLBr_00135|M.leprae_Br4923          RVAAQVEVRKPQIGLVSNVTGELAGPD--FGSPQYWGEHVSRAVRFVDSA
MUL_2005|M.ulcerans_Agy99           RIAAQVEAREPQIALVSNVTGELASADGGFGSAQYWVEHVRRAVRFADSA
MAV_3108|M.avium_104                AAAAGIEPRPPRIPLVSNLTGQLAGPG--YGTPQYWVDHVRRPVRFVDGV
Mb2074c|M.bovis_AF2122/97           AVAAGIAIGRPTIGVISNVTGQLAGDD--FGSAAYWRRHIRQAVRFADSV
Rv2048c|M.tuberculosis_H37Rv        AVAAGIAIGRPTIGVISNVTGQLAGDD--FGSAAYWRRHIRQAVRFADSV
MMAR_0101|M.marinum_M               LAAGDITAHPPRIALVSNLTGELAGPD--YGSAQYWVEHVRRPVRFADSV
MAB_3575c|M.abscessus_ATCC_199      AAAPLPAESAGAPIVISSVTGTAAEAAD--FTGDYWRAQLLGTVDFLGAA
TH_4458|M.thermoresistible__bu      GLLANLRPDDPRIPLYSTVTGDAVTGRG--FGAAHWMENLHSPVRFSAAV
                                                  : .. **             :*  :   .* *  ..

Mflv_0405|M.gilvum_PYR-GCK          RTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAAPRAIASLRKGVADRRQ
MSMEG_0408|M.smegmatis_MC2_155      RTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQ
Mvan_1003|M.vanbaalenii_PYR-1       RTLADLGCSVLMEIGPQPFLIAAALRVWPESAATPRAIPSLRKGPDARRQ
MLBr_00135|M.leprae_Br4923          RHLQTLGATHFIESGPSSGLMGAIEQSLAPAEAV--VVSMMGKDRPELAS
MUL_2005|M.ulcerans_Agy99           RQLHTLGVTHFVEVGPGSGLTGSIEQSLAPAEAV--VVSMLGKDRPEVAS
MAV_3108|M.avium_104                RLAESQGAGVFLEVGPGAALTSAVEQSLTSDRAM--SVVTMPKGRPEVDS
Mb2074c|M.bovis_AF2122/97           RFAQAAGGSRFLEVGPSGGLVASIEESLPDVAVT--TMSALRKDRPEPAT
Rv2048c|M.tuberculosis_H37Rv        RFAQAAGGSRFLEVGPSGGLVASIEESLPDVAVT--TMSALRKDRPEPAT
MMAR_0101|M.marinum_M               RNLEELGASHFIEVGPGGGLSSAIAQSLRSPEAV--TVPVLGKDRPEVNS
MAB_3575c|M.abscessus_ATCC_199      RTLADMEPSHIIEIGPRSTLLSLLAAADLIPDSQ--RIAPVPGAAATGLD
TH_4458|M.thermoresistible__bu      RRLLGRGHDAFLEISAHPMLLSAVQEDAADLGRSCTTLVSMRRGECGRDV
                                    *         ::* ..   * .               :  :         

Mflv_0405|M.gilvum_PYR-GCK          IADALAAAYIGGHKPDFAALHEQ-RGVRLELPTYPFQRRRFWPK----SA
MSMEG_0408|M.smegmatis_MC2_155      IADALASAYVGGHRPDFAAVHRQ-PRRPVELPTYPFQRRRFWPK----AS
Mvan_1003|M.vanbaalenii_PYR-1       LAEAVAAAYIAGHRLDFTGHDGG-PHRRLPLPTYPFQHRSYWPK----TA
MLBr_00135|M.leprae_Br4923          VLGAAGQLFATGMPVEWPAVFAGSSRRRVTLPTYAFQRRRFWETPGTDGT
MUL_2005|M.ulcerans_Agy99           VLTAFGQLFSTGMSVDWPAVFAGSGATRVDLPTYAFQRRRFWEVPGADGP
MAV_3108|M.avium_104                LLTAAARLFTAGADVRWSAAFTGLHARRVDLPTYAFARRRFWLSGDAVGS
Mb2074c|M.bovis_AF2122/97           LTNAVAQGFVTGMDLDWRAVVG--EAQFVELPTYAFQRRRFWLS-GDGVA
Rv2048c|M.tuberculosis_H37Rv        LTNAVAQGFVTGMDLDWRAVVG--EAQFVELPTYAFQRRRFWLS-GDGVA
MMAR_0101|M.marinum_M               LISAVGQLFSTGVGVDWSAVFAGSGGRQVGLPTYAFARRRFWLD-GSASA
MAB_3575c|M.abscessus_ATCC_199      FADALAALWQWGLDIDWRPLYAEHDRVVGRLPGYVFAD------------
TH_4458|M.thermoresistible__bu      LMTSLAALYASGHAVDWARVHPH-GSHCTAAPTYPWQRQRFWLDIDRCDT
                                    .  : .  :  *    :              * * :              

Mflv_0405|M.gilvum_PYR-GCK          GMAIDGRVGASAGSGILGSGKDLASGDSVYTSRLSVKTQPWLSDHVIYGT
MSMEG_0408|M.smegmatis_MC2_155      SIAVDG---GTAASGILGSGKDLASGDTIYTSRLSVKSQPWLADHVIYGT
Mvan_1003|M.vanbaalenii_PYR-1       GIRSDG----SSGSGLLGSAQDLASGDIVHTSRLSVKTQPWLSDHVIYGT
MLBr_00135|M.leprae_Br4923          ASVSGLGLGSTEHALLGAVVERPDSGGVVLTGRLSLANQPWLADHVIGGV
MUL_2005|M.ulcerans_Agy99           ADATGLGLGGAEHALLGAVVERPDSGGVVLTGRLALADQPWLADHVIGGV
MAV_3108|M.avium_104                ANIASLGLAEAEHPLLGAVLDRPDSGGVVLTGRLSTAAQPWLADHAVAGT
Mb2074c|M.bovis_AF2122/97           ADAASLGLAASEHALLGAVIDLPASGGVVLTGRLSPSVQGWLADHSVAGV
Rv2048c|M.tuberculosis_H37Rv        ADAAGLGLAASEHALLGAVIDLPASGGVVLTGRLSPSVQGWLADHSVAGV
MMAR_0101|M.marinum_M               ADVGEAGLVAAGHALLGAVVEQPDTGAVVLTGRLSLARQPWLADHLVGGA
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      GDGAGTG-------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          VVVPGATYAAMALAAVGTP--AHAKDVFFYEPIILPEKSSREVQLTVHPS
MSMEG_0408|M.smegmatis_MC2_155      VVVPGATYAAMALAAVGTP--ARLKDVFFYEPIILPEKASREVQLTLHPA
Mvan_1003|M.vanbaalenii_PYR-1       VVVPGATYAAMALAAMPTP--ARVQEVFFYEPIILGDKDSREVQLMLHRT
MLBr_00135|M.leprae_Br4923          VLFPGAGFVELVIRAGDEVGCAGVEELVLAAPLVLHPGSGVQVQVVVAAA
MUL_2005|M.ulcerans_Agy99           VLFPGAGFVELAIRAGDEVGCAVVEELVLAAPLVLHPGMGVQVQVIVGTA
MAV_3108|M.avium_104                VLFPGAGFVELALRAGDEVGCPVVEELTLSAPLSLPAGGTVQLQVVVADA
Mb2074c|M.bovis_AF2122/97           TIFPGAGFVELAIRAGDEVGCGVVDELTLAAPLVLPASGSVAVQVVVNGP
Rv2048c|M.tuberculosis_H37Rv        TIFPGAGFVELAIRAGDEVGCGVVDESTLAAPLVLPASGSVAVQVVVNGP
MMAR_0101|M.marinum_M               VLFPGTGFVELAIRAGDEVGCGVVEELTLATPLVLNAGTAVQVQVVVGSA
MAB_3575c|M.abscessus_ATCC_199      ------------------------EERFFASAATVGP-------------
TH_4458|M.thermoresistible__bu      ---------------------GTAERTVVPAPLPAPSASAAPTVDEVLLC
                                                            .   .  .                  

Mflv_0405|M.gilvum_PYR-GCK          VDGESK-FQVHSRPYGERGAEWALNAEGVVASGVGDSPAAAGDLEDPVDE
MSMEG_0408|M.smegmatis_MC2_155      DGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGSDPDAAADEQSDPVDE
Mvan_1003|M.vanbaalenii_PYR-1       DDADGWTFEVHSRPYGDRDADWSRNASGTVAAGVG--DAAPDAAADPVDN
MLBr_00135|M.leprae_Br4923          D-ESSRRAVSVYSRGDQSHGGWLLNAEGLLE------VDAAEATVDLSLW
MUL_2005|M.ulcerans_Agy99           D-DSGNRALSVYSRGDKSED-WLLNAEGMLG------VEAASSGADLSVW
MAV_3108|M.avium_104                AGQPGSRSVAVYSR--VAQSEWTLHAEGVLS------EAAPAPAAELSVW
Mb2074c|M.bovis_AF2122/97           D-ESGVRGVSVYSRGDVGTG-WVLHAEGALR------AGSAEPTADLAMW
Rv2048c|M.tuberculosis_H37Rv        D-ESGVRGVSVYSRGDVGTG-WVLHAEGALR------AGSAEPTADLAMW
MMAR_0101|M.marinum_M               G-QSGQRLVSMYSRADQPDQHWVLHAQGSVAPAAV--QPAAAASAELSTW
MAB_3575c|M.abscessus_ATCC_199      ----------------------LVHTQSVRT--------ATAPVREVASV
TH_4458|M.thermoresistible__bu      ADQRERRELLESYLRDRVAAELGVLPP------------LLDVAAPLSTL
                                                             .                        

Mflv_0405|M.gilvum_PYR-GCK          AIERLNRMRPQELFETFADLELAWGPTWSGSLKSLWLGEGEAIGDILVGA
MSMEG_0408|M.smegmatis_MC2_155      VIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDILVGA
Mvan_1003|M.vanbaalenii_PYR-1       AIERLTRTRPQQLFDAFADNDLAWGPAWCSSLRSLWVGTGEAVGDIAVGA
MLBr_00135|M.leprae_Br4923          PPEGAESVDISDAYPQLAERGYAYGPAFQG-LVAIWRRGSELFAEVVAPT
MUL_2005|M.ulcerans_Agy99           PPEGAESVDISDGYAQLADRGYAYGPGFQG-LVGVWRRDSELFAEVVAPS
MAV_3108|M.avium_104                PPADAEAVDVAGGYDDLAGRGYGYGPAFRG-LRAVWRRGAETFAEVELPE
Mb2074c|M.bovis_AF2122/97           PPAGAVPVEVADGYQQLAERGYGYGPAFRG-LTAMWRRGDEVFAEVALPA
Rv2048c|M.tuberculosis_H37Rv        PPAGAVPVEVADGYQQLAERGYGYGPAFRG-LTAMWRRGDEVFAEVALPA
MMAR_0101|M.marinum_M               PPAGAEAVDIGGLYERLARRGYGYGPAFQG-LRAVWRRGRDVFAEVGLPN
MAB_3575c|M.abscessus_ATCC_199      PPADDESQPDVGVVHRAVIR------------------------------
TH_4458|M.thermoresistible__bu      GIDSLTAAELRARVERDLGIVIPVAQLLNG--------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLYLPLRYGQVS
MSMEG_0408|M.smegmatis_MC2_155      ELAEQLGSEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLPLRYGQVT
Mvan_1003|M.vanbaalenii_PYR-1       ELGEHLGREPIHPVLLDLCTGIAGAALLAAAAQTDADPELFLPLRYGRVE
MLBr_00135|M.leprae_Br4923          --GVVVDGMGMHPALLDAVLHALGLAIENTQ----ATTEMRLPFCWRGVS
MUL_2005|M.ulcerans_Agy99           --GVAVDKMGMHPVVLDAVLHALGLTAEQNP----DSDETKLPFCWRGVS
MAV_3108|M.avium_104                QAGVSTGRFGIHPVLLDAALHALGVADKR--------LETVLPFSWQGVS
Mb2074c|M.bovis_AF2122/97           DAGVSVTGFGVHPVLLDAALHAVVLSAESAER---GQGSVLVPFSWQGVS
Rv2048c|M.tuberculosis_H37Rv        DAGVSVTGFGVHPVLLDAALHAVVLSAESAER---GQGSVLVPFSWQGVS
MMAR_0101|M.marinum_M               DEGLDLTDVGIHPALLDAVLHATMAAAGADV------AEMRLPFSWRGVS
MAB_3575c|M.abscessus_ATCC_199      -------------VLADVGGH-------------------------REDA
TH_4458|M.thermoresistible__bu      ------------PSVSDLAEWISTTMVGFGST------------TPEPES
                                                  : *                                 

Mflv_0405|M.gilvum_PYR-GCK          LQEKMPRRFYCRATWHEAPLDSETQVFDLEYLDRDGRHLGGVREFTVKRA
MSMEG_0408|M.smegmatis_MC2_155      LAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRA
Mvan_1003|M.vanbaalenii_PYR-1       VRERMPRRFYCRARWQTGGIDSETQVFDLDFLDHDGRNLGGIREFTVKRA
MLBr_00135|M.leprae_Br4923          LHAGGAGRVRARFTSAGAD---AIAVDIADSAGLPVLTVRSLVTRAMTAE
MUL_2005|M.ulcerans_Agy99           LHAGGAGRVRARLTMSGPD---SISVEIADAAGLPVLTVGALVTRAMSAA
MAV_3108|M.avium_104                LHAAGASRVRVRLAPAGAG---AVSVELADASGVPVLSVRELVTRAVSAE
Mb2074c|M.bovis_AF2122/97           LHAAGASAVRARIAPVGPS---AVSIELADGLGLPVLSVASMLARPVTDQ
Rv2048c|M.tuberculosis_H37Rv        LHAAGASAVRARIAPVGPS---AVSIELADGLGLPVLSVASMLARPVTDQ
MMAR_0101|M.marinum_M               LHAAGAAGLRARIAALDGGDGAAVSVELADAAGLPVLSVDSLVTRPVTAN
MAB_3575c|M.abscessus_ATCC_199      LHAAADLRDDLGFDSVQAM---QFADRIVNELDMPRLDPVAIQDNLTTIA
TH_4458|M.thermoresistible__bu      AGVPGRSRPPDGAVASGSGDGGRWIELLNQMPEVSDDTVDELLRQLLAAG
                                                                 :           :        

Mflv_0405|M.gilvum_PYR-GCK          PREALLRGLGG-DATRLLYTLGWHEVPVPESGDGAAP-QGTWLIGGFDEL
MSMEG_0408|M.smegmatis_MC2_155      PREALLRGLGG-DATRLLYTLGWHEVPPPPSADDAV---GTWLIAGFDEL
Mvan_1003|M.vanbaalenii_PYR-1       PREALLRGLGA-DATRLIYRVGWRETSPPVRDDGALGPSSTWLVAGLDAL
MLBr_00135|M.leprae_Br4923          QLRTAVTAAGG-ALEQGPMDLVWSPIPLSSDGHGG-GLPSVVSWADYCAG
MUL_2005|M.ulcerans_Agy99           QLRAAVAEAGGGAPDQGPLDVIWSPIPLSGSGTNGSAQPAVVSWADFCAG
MAV_3108|M.avium_104                QLAAAVAVRSG---SGELLDVAWSVIEPRNSLPDN---------------
Mb2074c|M.bovis_AF2122/97           QLRAAVSSSGP----DRLFEVTWSPQPSAAVEPLP-----VCAWG-----
Rv2048c|M.tuberculosis_H37Rv        QLRAAVSSSGP----DRLFEVTWSPQPSAAVEPLP-----VCAWG-----
MMAR_0101|M.marinum_M               QLNAAIAAAAG-APDDKLLEVAWSPIALNDRTIGGRDDVPVMLWDDHRDD
MAB_3575c|M.abscessus_ATCC_199      DLTKLVAGTAG---------------------------------------
TH_4458|M.thermoresistible__bu      ENHDDTQLH-----------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AVSVPGCIPADR----------------TNPESLRQLLTDAHGRGLPFSG
MSMEG_0408|M.smegmatis_MC2_155      AAKVPGCVPIDRN---------------TDLQVLGEVLSQAHARGAGFSG
Mvan_1003|M.vanbaalenii_PYR-1       ADDVPGSIRIGFDRIWDPDRDGRVVLDPADDEHWRRLFALADERRAPVAG
MLBr_00135|M.leprae_Br4923          --------------------------------------------RGNDTG
MUL_2005|M.ulcerans_Agy99           GDGG----------------------------------------AAGDAG
MAV_3108|M.avium_104                ---------------------------------------------PISEG
Mb2074c|M.bovis_AF2122/97           --------------------------------------------TTEDSA
Rv2048c|M.tuberculosis_H37Rv        --------------------------------------------TTEDSA
MMAR_0101|M.marinum_M               D-------------------------------------------GHGAGT
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          VVWRAARSDGDESD--AEVAARLEAEIAELLGAVHTVQGGEVKLPGGLWI
MSMEG_0408|M.smegmatis_MC2_155      VVWRCATPGRKESGSASAESARLEAEITNLLSAVHAAQGPSVKLPGGLWI
Mvan_1003|M.vanbaalenii_PYR-1       VVLGVTGRARPEEPS-ADFAARLEAQIRDVLGAVHSLSALGAKPAAGLWI
MLBr_00135|M.leprae_Br4923          VVVWEFGSASAGAQAPVDSVAAVYSATHAALQVLQFWFGQ--DRAGTLVV
MUL_2005|M.ulcerans_Agy99           VVVWEP------NPAGEDVVGPVYAATHAALEVLQSWFDG--DRAGTLVV
MAV_3108|M.avium_104                VTVWEP------AAVDGAGPAAVHAATHQALGVLQSRLAG--EAGGVLVV
Mb2074c|M.bovis_AF2122/97           AVVFES------VPLAGDVVAGVYAATSSVLDVLQSWLTR--DGAGVLVV
Rv2048c|M.tuberculosis_H37Rv        AVVFES------VPLAGDVVAGVYAATSSVLDVLQSWLTR--DGAGVLVV
MMAR_0101|M.marinum_M               VVIWES-----CCAADDDVVRSAYAATHAALAVLQSWLSG--DRPGTLVI
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          VTERAVATESGEPVDPVQAALWGFGRTAINEEPALRCRLVDCDGSPQAVQ
MSMEG_0408|M.smegmatis_MC2_155      VTEHGVACESGEPVDPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVD
Mvan_1003|M.vanbaalenii_PYR-1       VTERAVAAEAGEPVDPVQSALWGLGRTLIAEEPGLRCLLVDLDGSEDAGP
MLBr_00135|M.leprae_Br4923          LTRGAVGLVGEGISDLAAAAVWGMVRSAQSEHSGK-IVLIDTDSAVD---
MUL_2005|M.ulcerans_Agy99           LTHGAVAMPGENVSDLAGAAVWGIVRSAQAENPGR-IVLVDADAAVE---
MAV_3108|M.avium_104                STRGAVGLPGEDVADLAGAAVWGLVRSAQAEHPGR-VVLVDTDGSLD---
Mb2074c|M.bovis_AF2122/97           MTRGAVALPGEDVTDLAGAAVWGLVRSAQTEHPGR-IVLVDSDAPLDD--
Rv2048c|M.tuberculosis_H37Rv        MTRGAVALPGEDVTDLAGAAVWGLVRSAQTEHPGR-IVLVDSDAPLDD--
MMAR_0101|M.marinum_M               VTHGGVALTDEGVKDLAAAAVWGLVRSAQSEHPGR-IVLIDTDSAPTDPE
MAB_3575c|M.abscessus_ATCC_199      --------------------------VAQPEHTGA-GI------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ALAALLSTP-VDEPELAVRQGKLLASRLLPWSRSGHLTVPRGGDYVLAPT
MSMEG_0408|M.smegmatis_MC2_155      LLAALLAAPGIQEPEIAVRQGKLLASRLLPWARSGHLTLPRGGDFVLAPT
Mvan_1003|M.vanbaalenii_PYR-1       ALARLLGAP-GDEPELALRQGRLLVPRLLPWSRSGQLAIPRGTDYVLAPT
MLBr_00135|M.leprae_Br4923          ----VAVLADLGESQLLVRCNTVHAARLSPAPQ--LLALPVGESMWRLAA
MUL_2005|M.ulcerans_Agy99           ----AAELVAVGEPQLVVRSGAAHAARLAPAAP--LLAVPADESAWRLAA
MAV_3108|M.avium_104                ----LATVIGCGEPQLVVRDGVAYRARLRPAGRRALLELPGPPAVWRLAA
Mb2074c|M.bovis_AF2122/97           --SALAAVVTTGEPQVLWRRGEVYTARVHGSRAVGGLLVPPSDRPWRLAM
Rv2048c|M.tuberculosis_H37Rv        --SALAAVVTTGEPQVLWRRGEVYTARVHGSRAVGGLLVPPSDRPWRLAM
MMAR_0101|M.marinum_M               VLMDLANLAGRGEPQLLVSGGAVYGARLAPIPP-----------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ERGAIDN---LRLTDSEVPPPAEGYVQVRVEAAGLNFRDVLNVLGLYPGD
MSMEG_0408|M.smegmatis_MC2_155      ERGAIDN---LRLTETDVPEPDEGYVQVRVEAAGLNFRDVLNVLGLYPGD
Mvan_1003|M.vanbaalenii_PYR-1       ERGVLDN---LRVSETEVTAPPEGHVQVRVEAAGLNFRDVLNALGLYPGD
MLBr_00135|M.leprae_Br4923          DGGGTLEDLVIQPCPEVQAPLQAGHMRVAVAAVGVNFRDVVAALGMYPGQ
MUL_2005|M.ulcerans_Agy99           GGGGTLEDLVIEPCPEVQAPLAAGQVRVAVRAVGVNFRDVVAALGMYPGA
MAV_3108|M.avium_104                GDAGTLEDLAVQEHP--AAELAPGQVRVRVAAAGVNFRDVLVALGMYPGA
Mb2074c|M.bovis_AF2122/97           STAGTFENLRLELIPDADAPLGPGQVRVAVSAIAANFRDVMIALGLYPDP
Rv2048c|M.tuberculosis_H37Rv        STAGTFENLRLELIPDADAPLGPGQVRVAVSAIAANFRDVMIALGLYPDP
MMAR_0101|M.marinum_M               --------------------------------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          PGPIGGDFAGTVTQLGEGVTGLDVGQRVYGSMQGAFASRFNVPGQFLAPI
MSMEG_0408|M.smegmatis_MC2_155      PGPIGGDFAGTVTQLGAGVSGLEIGQRVYGSMQGAFASRFNVPAQFLAPI
Mvan_1003|M.vanbaalenii_PYR-1       PGPIGGELAGVVTAPGPDVDGFDVGQRVFGFAVGAFASRVNVPVQFLAPV
MLBr_00135|M.leprae_Br4923          APPLGAEGAGVVIEIGPEVTGVAVGDAVMGFLGG-AGPLAVVHQQLITQM
MUL_2005|M.ulcerans_Agy99           APPLGAEGAGVVLEVGPQVSGVAVGDSVMGFLGG-AGPLSVVDQQLITRM
MAV_3108|M.avium_104                AQ-LGAEGAGVVTEVGAGVTDVAVGDAVMGIFGL-VGSEAAVDRRLVTRV
Mb2074c|M.bovis_AF2122/97           DAVMGVEACGVVIETSLNKGSFAVGDRVMGLFPEGTGTVASTDQRLLVKV
Rv2048c|M.tuberculosis_H37Rv        DAVMGVEACGVVIETSLNKGSFAVGDRVMGLFPEGTGTVASTDQRLLVKV
MMAR_0101|M.marinum_M               --------------------------------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          PDGVSAVEAATIPAAALTVR-LSFDWAQVKSGDKVLIHAASGGVGLAAVQ
MSMEG_0408|M.smegmatis_MC2_155      PDGIGAVEAATIPAAALTVR-LAFDWAQLKPGDKVLIHAASGGVGLAAIQ
Mvan_1003|M.vanbaalenii_PYR-1       PEGISAVAAATTPAAVLTAG-LAFDWAALRAGDRVLIHAASGGVGLAAVQ
MLBr_00135|M.leprae_Br4923          PQGWSLAEAAAVPVVFLTALFGLADLAGIRAGESVLIHAGTGGVGMAAVQ
MUL_2005|M.ulcerans_Agy99           PQGWSFAQAAAVPVVFLTALFGLQDLAKIQPGESVLIHAGTGGVGMAAVQ
MAV_3108|M.avium_104                PPGWSMAQAAGIPVVFLTAYYGLSVLAGLRAGQRVLVHAATGGVGMAAVQ
Mb2074c|M.bovis_AF2122/97           PAGWSHTAAATTSVVFATAHYALVDLADVQPGQRVLIHAGTGGVGMAAVQ
Rv2048c|M.tuberculosis_H37Rv        PAGWSHTAAATTSVVFATAHYALVDLAAARSGQRVLIHAGTGGVGMAAVQ
MMAR_0101|M.marinum_M               --------------------------------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          MAQQCGAEVYATASTFKRATLRKLG--VKHVYDSRTTDFAEQILADTDGA
MSMEG_0408|M.smegmatis_MC2_155      MAQQSGAEVFATASTFKRSTLRRLG--VKYVYDSRTTDFADQILADTNGA
Mvan_1003|M.vanbaalenii_PYR-1       LARQRGATVFATASGYKRPMLRAMG--VDHVYDSRTTDFADQILADTDGA
MLBr_00135|M.leprae_Br4923          FARHWGVEIFVTASRGKWDTLRDMGFDDDHIGDSRTLEFEEKFLAVTDGR
MUL_2005|M.ulcerans_Agy99           LARHWGVEIFVTASRGKWDTLRAMGFDDDHIGDSRTLDFEEKFLAVTDGR
MAV_3108|M.avium_104                LARHWGAEVFATASRGKWDTLRAMGFDDAHIADSRTLDFEQKFGAAPG--
Mb2074c|M.bovis_AF2122/97           LARHLGLEVFATASKGKWDTLRAMGFDDDHISDSRSLEFEDKFRAATGGR
Rv2048c|M.tuberculosis_H37Rv        LARHLGLEVFATASKGKWDTLRAMGFDDDHISDSRSLEFEDKFRAATGGR
MMAR_0101|M.marinum_M               ---------ALSATDGDCPTS-----------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GVDVVLNSLTSEGFIEATLRATAQHGRFAEIAKRDIWTVEQMAAARPDLA
MSMEG_0408|M.smegmatis_MC2_155      GVDVVLNSLTSAGFVEATLKATAQGGRFAEIAKRDIWSHEQMAEARPDIA
Mvan_1003|M.vanbaalenii_PYR-1       GVDVVLNSLTNDGFVAATVRATARNGRFAEIAKRDIWSPEQMAAARPDID
MLBr_00135|M.leprae_Br4923          GVDVVLDSLAGD-FVDASLRLLVRGGRFLEMGKTDIRDAQEIAANYPGVQ
MUL_2005|M.ulcerans_Agy99           GVDVVLDSLAGD-FVDASLRLLVRGGRFLEMGKTDIRDADKIAANYPGVW
MAV_3108|M.avium_104                GMDVVLNSLAGE-FNDASLRLLGPGGRFIEMGKTDLRDPDVVARAHPGVR
Mb2074c|M.bovis_AF2122/97           GFDVVLDSLAGE-FVDASLRLVAPGGVFLEMGKTDIRDPGVIAQQYPGVR
Rv2048c|M.tuberculosis_H37Rv        GFDVVLDSLAGE-FVDASLRLVAPGGVFLEMGKTDIRDPGVIAQQYPGVR
MMAR_0101|M.marinum_M               --------------------------------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          YEIVALDTVMFTEPDRIRDLLTEVSAGLRDGAWTPLPAEVYPLTEARAAF
MSMEG_0408|M.smegmatis_MC2_155      YEIVALDTVMFTEPDRIRDLLTEVSDGMARGEWTPLPAEIYPITEARSAF
Mvan_1003|M.vanbaalenii_PYR-1       YEVLALDAVMQQDPDRIQLLLADLADSLARGETAPLPFEAYPLAEATTAF
MLBr_00135|M.leprae_Br4923          YRAFDL---SEAGPVRMQEMLCEVRELFDTQVLHRLPVTSWDVRCAPAAF
MUL_2005|M.ulcerans_Agy99           YRAFDL---SEAGPVRMQEMLAEVRELFDTAVLHRLPVTTWDVRCAPAAF
MAV_3108|M.avium_104                YRAFDL---MEAGPDRIAAMLAEVMELFAAGALTPLPVKAFDARCAADAY
Mb2074c|M.bovis_AF2122/97           YRAFDL---FEAGPDRIAQILAELATLFGDGVLRPLPVTTFDVRRAPAAL
Rv2048c|M.tuberculosis_H37Rv        YRAFDL---FEPGPDRIAQILAELATLFGDGVLRPLPVTTFDVRCAPAAL
MMAR_0101|M.marinum_M               -----------DGPAELASVLDP---------------------------
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          RRMQQARHIGKIVVQIP-NPLQPQPDRSYLITGGLGAIGLHTAGYLAQLG
MSMEG_0408|M.smegmatis_MC2_155      RRMQQARHIGKIVLQVP-KPLQPQQDRSYLITGGLGAIGLHTAAYLAQLG
Mvan_1003|M.vanbaalenii_PYR-1       RRMQQARHTGKIILQMP-KPLQPHGDRSYLITGGLGALGLHAAAYLAQLG
MLBr_00135|M.leprae_Br4923          RFMSQARHIGKVVLTMPSALADGLAEGTVLITGASGAIGGVLARHMVSAY
MUL_2005|M.ulcerans_Agy99           RFMSQARHIGKVVLTMPSALADGLADATVLITGATGAVGAVLARHMLDGY
MAV_3108|M.avium_104                RFVSAARHIGKVVLTMPDGPAG-LSGGTALITGATGMAGAALARHLVARH
Mb2074c|M.bovis_AF2122/97           RYLSQARHTGKVVMLMP----GSWAAGTVLITGGTGMAGSAVARHVVARH
Rv2048c|M.tuberculosis_H37Rv        RYLSQARHTGKVVMLMP----GSWAAGTVLITGGTGMAGSAVARHVVARH
MMAR_0101|M.marinum_M               -------------------------AGTVLITGGTGMAGGVLARHVVGAG
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          -AGDIVLTSRRAPDAAAQQAIADIADRTKARLHVFTADVGVEADVAALLE
MSMEG_0408|M.smegmatis_MC2_155      -AGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVGDEAQVADLLA
Mvan_1003|M.vanbaalenii_PYR-1       -AGDIVLTGRRMPDAATERAISEIAERYHCRIHTFAADVGDESAVRDLLE
MLBr_00135|M.leprae_Br4923          GVRHLVLASRRGDRAEGAVELAAELVGAGAKIQVVACDVADNDAVRGLFA
MUL_2005|M.ulcerans_Agy99           GVRHLVLASRRGDRAEGAAELAAELSEAGANVQVVACDVADRDAVEAMLA
MAV_3108|M.avium_104                RVPHLMLVGRRGEAAPGMAELAAELRGAGASVSVLSCDVGDRDAVAAMLA
Mb2074c|M.bovis_AF2122/97           GVRNLVLVSRRGPDAPGAAELVAELAAAGAQVQVVACDAADRAALAKVIA
Rv2048c|M.tuberculosis_H37Rv        GVRNLVLVSRRGPDAPGAAELVAELAAAGAQVQVVACDAADRAALAKVIA
MMAR_0101|M.marinum_M               GVRHVVLASRQGEQAPGVAELVSELSAAGAEVLVLACDVADRDAVAQMME
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          RIRAELPPLAGVAHLAGVLDDALLSQQSVERFRTALAPKAFGAVHLDRLT
MSMEG_0408|M.smegmatis_MC2_155      RIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHLDRLT
Mvan_1003|M.vanbaalenii_PYR-1       RIRTELPPLAGVAHLAGVLDDALLPQQSPERFRTTLAPKAFGAWHLHRLT
MLBr_00135|M.leprae_Br4923          QLSREFPPVRGVIHAAGVLDDGAITSLTPDRVDTVLRAKVDAAWNLHEAT
MUL_2005|M.ulcerans_Agy99           RLSGEYPPVRGVIHAAGVLDDAVISSLTPERIDTVLRAKVDAAWNLHEAT
MAV_3108|M.avium_104                QVPARYP-LRSVFHAAGVLDDAVIASLTPARIDTVLRAKVDGAWNLHELT
Mb2074c|M.bovis_AF2122/97           DIPVQHP-LSGVIHTAGALDDAVVMSLTPDRVDVVLRSKVDAAWHLHELT
Rv2048c|M.tuberculosis_H37Rv        DIPVQHP-LSGVIHTAGALDDAVVMSLTPDRVDVVLRSKVDAAWHLHELT
MMAR_0101|M.marinum_M               QVRRRCPPLTGVIHAAGVLDDTVIASLTPDRMNPVLRAKVDGAWHLHQLT
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          RVDDLDFFLVSSSVSSLFGSPGQSNYATANAFLDGLVAQRRAQGLPATGV
MSMEG_0408|M.smegmatis_MC2_155      RDDDLDFFIVSSSVSSLFGSPGQANYATANAMLDGLVAKRRAQGLVATGI
Mvan_1003|M.vanbaalenii_PYR-1       RDTELEFFIVYSSGSSVLGSPGQANYATANAVLDGLVAHRKARGLPATGV
MLBr_00135|M.leprae_Br4923          RDLDLLMFVLCSSIAATVGSPGQGNYSAANAFLDGLAAYRQAAGLAGTSL
MUL_2005|M.ulcerans_Agy99           LDLDLSMFVLCSSIAATVGSPGQGNYSAANSFLDGLAAHRQAAGLAGISV
MAV_3108|M.avium_104                KDLDLSAFVVFSSMAGIVGAPGQGNYAAANSFLDALAIHRHAHGLPALSV
Mb2074c|M.bovis_AF2122/97           RDLDVSAFVMFSSMAGLVGSSGQANYAAANSFLDALAAHRRAHGLPAISL
Rv2048c|M.tuberculosis_H37Rv        RDLDVSAFVMFSSMAGLVGSSGQANYAAANSFLDALAAHRRAHGLPAISL
MMAR_0101|M.marinum_M               RGLGLSMFVLCSSIAGVMGSPGQGNYAAANTFLDALAAHRRATGLAGLSV
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          NFGPWARGGMASSEAAAAN---ISAQGLIPLEPSAALTAMAEVVANGTAQ
MSMEG_0408|M.smegmatis_MC2_155      NFGPWGQGGMASSEAATAN---ITAQGLIPLDPSAALHALAEVIANGSGQ
Mvan_1003|M.vanbaalenii_PYR-1       NWGPWAQGGMATSDAARAN---LGAQGLIPLEPTAALNALGEIVAHGIAS
MLBr_00135|M.leprae_Br4923          AWGLWEQPGGMNAHLSSRDLARISRSGLAPMNPAQALELFDAALVIDHPF
MUL_2005|M.ulcerans_Agy99           AWGLWEQSGGMAAHLSSRDLARMSRSGLAPMNPEQAVGLLDAVLAINHPL
MAV_3108|M.avium_104                AWGMWEEPSAMTAHLEERDKARMSRAGLSALSTRQALDLLDDALLGEQPL
Mb2074c|M.bovis_AF2122/97           GWGLWDQASAMTSGLATVDFKRFARDGIVAMSSADALQLFDTAMIVDEPF
Rv2048c|M.tuberculosis_H37Rv        GWGLWDQASAMTGGLATVDFKRFARDGIVAMSSADALQLFDTAMIVDEPF
MMAR_0101|M.marinum_M               QWGLWEQTSAMTGHLGERDLARIRRSGLAPMSVGQAVELFDAAVLLDRST
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ATVLKANWQRAAKVLGSSRPPILDLVLPSAVG---------EITGDSELL
MSMEG_0408|M.smegmatis_MC2_155      ATVLKANWQRAAKVLGSARPPILDLVLPSAAG---------EATGDSELL
Mvan_1003|M.vanbaalenii_PYR-1       AVVLKANWQRAAKLLGATRPPILDHVLPSAVA---------AGPGDSALL
MLBr_00135|M.leprae_Br4923          MVTALLDRAALDAQAQAGALPPLFSRLVRRSRRRQIEDPGDATQSKLALV
MUL_2005|M.ulcerans_Agy99           MVATLLDRPALEARAQAGGLPPLFAGVVRRPRRRQIEDTGDAAQSKSALA
MAV_3108|M.avium_104                VVGTRLDRAALAQHRAA--LPPLLSELAGRPARRMLEHTDMVSLTG--LR
Mb2074c|M.bovis_AF2122/97           MLPAHIDFAALKVKFDGGTLPPMFVDLINAPTRRQVDDSLAAAKSKSALA
Rv2048c|M.tuberculosis_H37Rv        MLPAHIDFAALKVKFDGGTLPPMFVDLINAPTRRQVDDSLAAAKSKSALL
MMAR_0101|M.marinum_M               VVAACLDRNALASPAVSAELPMLFHSLLPRPSRRVIN--KDATTHESGLA
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          KQLQEIPVPQRAGFVTEFLQKEVQNFLRLAQPPAATS--RFLDLGTDSLM
MSMEG_0408|M.smegmatis_MC2_155      KQLMEIPIPQRAGFVTEFLQREVQNFLRLASPPAASS--RFLDLGTDSLM
Mvan_1003|M.vanbaalenii_PYR-1       KQLQDVPEAQRGSFVTEHLQRELQQILGLAQPPAATG--RFLELGMDSLM
MLBr_00135|M.leprae_Br4923          QRLQGLAANRQLELLVGVVCLQAAAVLGRPSPEDIDPNTKFQDLGFDSLT
MUL_2005|M.ulcerans_Agy99           ERLNGLSAGERQDALVGLVCLQAAAVLGRPSPEDIDPEAGFQDLGFDSLT
MAV_3108|M.avium_104                ARLAGMNPEQRQAELVELVCGNAAAVLG-HSTADVDPGDAFSDLGFDSLT
Mb2074c|M.bovis_AF2122/97           HRLHGLPEDEQHAVLLDLVRSHIATVLGSASPEAIDPDRAFQDLGFDSLT
Rv2048c|M.tuberculosis_H37Rv        QRLEGLPEDEQHAVLLDLVRSHIATVLGSASPEAIDPDRAFQELGFDSLT
MMAR_0101|M.marinum_M               QRLQALSPHQQHQLLVETVRNQAAVVLGRPSGQDIDPECTFQDLGLDSLT
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AIELRNRLHSQFGGAFTINATAVFDYPTIGGLAEYLVAQLPDAETPQAAP
MSMEG_0408|M.smegmatis_MC2_155      AIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLPDAEAPETA-
Mvan_1003|M.vanbaalenii_PYR-1       AVELRNRLVGQFGSGFTITATAVFDYPTIGALAEYLAAQTPESTEEGTEM
MLBr_00135|M.leprae_Br4923          AVELRNRLKSATG--LTLPPTVIFDHPTPTAVAEYVAQQMLKSRPAESGD
MUL_2005|M.ulcerans_Agy99           AVELRNRFKSATG--LTLPPTVIFDHPTPTAIAEYVGRQIPDSQATQAEE
MAV_3108|M.avium_104                AVELRNRLKIATG--LTLSPTVIFDHPTPAALAEHLGGQLTSAGPTPAAP
Mb2074c|M.bovis_AF2122/97           AVEMRNRLKSATG--LSLSPTLIFDYPNSAALAGYMRRELLGSSPQDTSA
Rv2048c|M.tuberculosis_H37Rv        AVEMRNRLKSATG--LALSPTLIFDYPNSAALAGYMRRELLGSSPQDTSA
MMAR_0101|M.marinum_M               AVELRNRLKAASG--LSLSPTLIFDYPTPATLARHLAQQLIGTGTTGSAQ
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          QSESEPGPDVTE--------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       KTADPDGQPATVGHADVVLQTS----------------------------
MLBr_00135|M.leprae_Br4923          ETSQAVEPKVEEVSVHA---------------------------------
MUL_2005|M.ulcerans_Agy99           E--KLPESDGEMVSVTA---------------------------------
MAV_3108|M.avium_104                AETAAPPDRSSRIDEVVSELQTLLTQPGLSPGDRAQLVTRLQSLLSTPPQ
Mb2074c|M.bovis_AF2122/97           VAAGEAELQRIVASIPVKRLR------------QAGVLDLLLALANETET
Rv2048c|M.tuberculosis_H37Rv        VAAGEAELQRIVASIPVKRLR------------QAGVLDLLLALANETET
MMAR_0101|M.marinum_M               IESQLETLQQTLLAIEDGDKQ--------------RVAAQLRKFLTRLLA
MAB_3575c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ----------------------------------
MSMEG_0408|M.smegmatis_MC2_155      ----------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       ----------------------------------
MLBr_00135|M.leprae_Br4923          ----------------------------------
MUL_2005|M.ulcerans_Agy99           ----------------------------------
MAV_3108|M.avium_104                PSGHPEFPEDAFDDDIATATDSQLFAILDDEAGP
Mb2074c|M.bovis_AF2122/97           SGQDPALAPTAEQEIADMDLDDLVNAAFRNDDE-
Rv2048c|M.tuberculosis_H37Rv        SGQDPALAPTAEQEIADMDLDDLVNAAFRNDDE-
MMAR_0101|M.marinum_M               PAESGRPLDDRIKDATSPSEILQLIDAGSIES--
MAB_3575c|M.abscessus_ATCC_199      ----------------------------------
TH_4458|M.thermoresistible__bu      ----------------------------------