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LVAVAIIGIGCRFPGGIGDADSFWNFVLHKGDAVADIPKDRWDADKYYDPDPDTPGRMYTRRGSFLTQEF RRFDADFFGISHREAAVLDPQQRLLLETTWEALDDAGIAGQAVGGNVGTFIGGFMNDNMISRGLARNLEK INNFAAFSASQTLLSNRIAHALDLWGPSMTVDTACSSSLVTTHLAVRAVANGECDVALAGGVNVMFQPET FITMCKGRFLAADGRSKSFDAAADGYGRGEGVGIVVLKNLEQAQRDGDHIYAVIRGSGVNQDGRTIALPV PNPVSQQRLADRVIKEAGIDPALVGYIEAHGTGTSVGDPLEAQALGHSYGRVAGRARPLVIGSVKNNFGH TEAAAGVAGLIKAALTVQRRTIAPQVVLDKLNPEIPFDQLQIRIPTEVEPYPDLGAPAYAAVNSFGYGGT NAHVLVQEPPAPVQTEAPARDSIRIFPVSARSGSALHEVAGRYAKQLSSDLSQDGAQRLKTAATARRAQH YLRKGFIYRDADDLLAQLNTYAASDEAAPPRALVEGISDPVFVFSGMGPQWWGMARALLERPGIFRDAAA EIDEVFQEISGWSVIAELLRPQADSRVSRTEIAQPANFLVQSALAKHLQQFGIRPTAVVGHSVGEVAAAY VSGALSLRDAATVSFHRSRLQAKTAGSGGMLAVGLDAEEAQRRAARFGSAVCVAAINSTAATTLSGDSAA LQTLHDELAGDGIFARMLHVEVPYHSQLMDPILGELATALAGLTPRKAAVPVYSTVTGEKMHSAAFAEPD YWCKNVRDSVLFAKAVDTLIVDRYRVFLELGPHPVLLGNIRESFVRHSVSGAAIQTLHRDQDDEQSVLQA IADLYAVGAIDAPGQADIYESGVVPHMDLPKYPWSQEEVWEEDPLTLRARYGDADRFALLGDRVDALTPQ WEVTLAPANLPWLPDHTVLGSVVLPGTAYLDAALSAVRQRSGRAQAGLDSVVFAVPLVVADHDAPITRIT VDEPTKRFTVNGRSAHTQLWTAHANGRLVEANLGSKRIDVSAWSANDRVFDGEDVYKGLSAVGLSYGPAF QRIQSVRIGSAGCVAQLASPESVSAQRHAVHPALADAALQCIAVLLAARPELDIPPTAHVPASIDRVRLY GEVPEDPVAVVEITSTQPLCANAYLASRDGEVALAMTGVTLRPVGSASTPLSELEQYFYEPRWEPLEEEI EGQPAPTTTAPAARPANVIVEIAQVPLAVAEGARRAAAAGVVVLNADTVEKANLAVTFAEALDRDEFLRV LVTVGSGKSAVENVAGLVTVAQSLRMVMEAETERGVVSPDVQAVLVSKNAFLAPGDRDLDLDQAALVGAR RVLANEQHPAKWSLVDLPAAVSAEEVTAEIGAMNRAEEVAVRQGLRWTQRMRRSLPELVAPWEEPFEPTD PEVAYEVQIPDTRTLKDIKLRACDRIEPGPRQVEVRVETVGLNYKDPLKVLGILTERELGKTYFKLEPGM EGFGVITRVGSQVTEVRVGESIAVAERGLLRRYLTFDLDGGAAWEPIADVHLQRDEFDPLAVGSGVPFFT AGYAFYKLADVRPGETVLIHGAAGGMGMAAVQVAANMGAVVYATAGSEERRRAALDLGATAAFDSRSVGF VDDILQITEGRGVDVIYNSLPGEMIAQNFAVAGEFCRIIEIGKADIYFGGATDLKPFSGNLSFHSIDMDR MLRLRPEIFRELRRECTEMLTAGKLTPLPYTRFPIEEVVGAFEAVFRAEHMGRIVLDLRDQTPTLLPRKP EPAPVRPGHSYLITGGFGGFGLATARSLARAGATHLILASRSGAATEVARAQIEALRAADVDVWEEQVDI SDYDQVADLIAKVEASGHPLRGVFHAAAVAHDEVIADISAESLRKVFRPKVQGALNLDKVTREHDVPLDH FVLYSSISGLIGIVPQLTYAAANSVLDGLAASRRAAGLPALSVSWGAMSGGGMAESDAIVKFLDSVGLRR LNMDMGAAFMRECSRFPLSHVAIAGIDWGVLRTPLPSTAKSTRFAHLSAEAAAVSNEQAAFRAAVLALPE EERGPMVTKELAKELANVLKVDVDSIDPKGPIADLGIDSLMAVEFAARAGKQLNIQISAFQFTPDLTLEA VGARVALLIAQGVGDPDHDGI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2212 | - | - | 100% (2121) | polyketide synthase |
| M. abscessus ATCC 19977 | MAB_3148c | - | 0.0 | 32.58% (2130) | polyketide synthase Pks5 |
| M. abscessus ATCC 19977 | MAB_0939 | - | 0.0 | 31.56% (2161) | polyketide synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3855c | pks2 | 0.0 | 32.47% (2134) | polyketide synthase PKS2 |
| M. gilvum PYR-GCK | Mflv_0405 | - | 0.0 | 32.24% (2199) | beta-ketoacyl synthase |
| M. tuberculosis H37Rv | Rv3825c | pks2 | 0.0 | 32.47% (2134) | polyketide synthase PKS2 |
| M. leprae Br4923 | MLBr_00139 | mas | 0.0 | 32.16% (2158) | putative mycocerosic synthase |
| M. marinum M | MMAR_2344 | pks5_1 | 0.0 | 32.73% (2139) | polyketide synthase, Pks5_1 |
| M. avium 104 | MAV_2370 | - | 0.0 | 32.12% (2136) | mycocerosic acid synthase |
| M. smegmatis MC2 155 | MSMEG_4727 | - | 0.0 | 33.02% (2159) | mycocerosic acid synthase |
| M. thermoresistible (build 8) | TH_4621 | - | 0.0 | 33.26% (1858) | PUTATIVE mycocerosic acid synthase |
| M. ulcerans Agy99 | MUL_2010 | mas | 0.0 | 32.24% (2174) | multifunctional mycocerosic acid synthase membrane-associated |
| M. vanbaalenii PYR-1 | Mvan_1003 | - | 0.0 | 32.17% (2185) | beta-ketoacyl synthase |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK --------------MGSAAHQGESAHR-FAIVGYAGRFPGARDAESFWEL
Mvan_1003|M.vanbaalenii_PYR-1 MTDLQKRALQAIEVLRARVRELEGAGDGYAIVGYALRFPGAADADEFWDV
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK LADGRDAISEVPEDRWDVEAFFDPDPSTPGKVVTRRAGFVDDVSGFDAPF
Mvan_1003|M.vanbaalenii_PYR-1 LRGGRDAISEVPQDRWDADEFFDADPEAAGKMVTRRAGFVEDVAGFDAPF
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK FGMSTREVRLMDPQHRLLLETAWRAIEHSGTAPSELANTNTGVFVGLATH
Mvan_1003|M.vanbaalenii_PYR-1 FGVSAREAMFMDPQHRLLLETAWRAVEHSGTAPSALAGTRTGVFMGLSTH
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK DYLGMASDELSYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACS
Mvan_1003|M.vanbaalenii_PYR-1 DYLGMLTDNLTHDAIEAYLGTGTSPAAAIGRISYRLGLQGPAVAVDTACS
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK SSLVAIHQACQALRLGECDLALAGGANVILTPATMITFSNAHMLAPDGRC
Mvan_1003|M.vanbaalenii_PYR-1 SSLVAVHQACQALRLAECDVALAGGVNVLLSPATMINFSRARMLAPDGRC
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK KTFDAAADGYVRGEGCGVIVIKRLEDAVRDGDRIRAVIRGSAINQDGASG
Mvan_1003|M.vanbaalenii_PYR-1 KTFDATADGYVRGEGCGVVVVKRLADAIRHGDRIRAVIRGSAVNQDGASG
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GLTVPNGVAQQRVIGDALSRAGLAPGDVDYLEAHGTGTSLGDPIEAQAAG
Mvan_1003|M.vanbaalenii_PYR-1 GLTVPNGAAQQRVIADALTNAGLTAADVDYLEAHGTGTPLGDPIEVQAAG
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK AALGPGREPQRPLLIGSAKTNIGHLEAAAGIAGVIKVVLSLEHETLPKHL
Mvan_1003|M.vanbaalenii_PYR-1 AVLGVGREPDRPLLIGSVKTNIGHLEAASGIAGLLKVILSLEHQVLPKHL
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK NFENPSPHIPWDRLPVEVVKESIPWRRGQRGGRPRIAGVSSFGFAGTNAH
Mvan_1003|M.vanbaalenii_PYR-1 NFRSPSPHIPWNRLPVRIVDDPVPWTR---SGRSRVAGISSFGFSGTNAH
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK VILEEAPLAAEP--AQESVDDGRFTLLPLSARTPAALMAVADRYRDWLVA
Mvan_1003|M.vanbaalenii_PYR-1 VLVEEAPRADRAGAAPQPAAPGGFGMLPLSARTPDALAATAHRLRTWLAA
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK NPDATLADLCFTAGTARSHLEHRAALVVNTREAALDLLGALADDRPAPGL
Mvan_1003|M.vanbaalenii_PYR-1 NPDASWPDLCFTAAVGRSHLRHRAALVVDSRSSVEELLGALAEDRPGPGL
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK VRGESHDTPKTAWLFTGQGSQYPGMSRELFDTEPLFAETLRECAAAVDGM
Mvan_1003|M.vanbaalenii_PYR-1 ARGECGDPPKTAWLFTGQGSQYPGMGRELFDTEPVYREVMTRCAEAVADV
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK LEKPLLDVIFDTDGVLDTDSNETLRHTSYAQPALFAVEMGLARLWQSWGF
Mvan_1003|M.vanbaalenii_PYR-1 LERPLLDVVFDAD------GGEALRHTSYAQPALYAVEMGLARLWQSWGI
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK EPDVVLGHSVGQYAAACVAGVLSLRDGARLMAERGRLFGSLPSGGRMAAV
Mvan_1003|M.vanbaalenii_PYR-1 EPDVVLGHSVGQYAAACVAGVMGLEDGAVLLAERGRLFGSLPEGGRMAAV
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK FAAAERVEALTDEYPALSVAAYNGANTVLSGPATDLERAVAGLVADGVRC
Mvan_1003|M.vanbaalenii_PYR-1 FAPADRVESCTVDSPLLSVAAYNGDNTVLSGPAGDLERAVAGFSAAGVRC
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK DWLETSHAFHSALLDPILDDFESYARGITFTAPQRILIDNRTGAALGRSV
Mvan_1003|M.vanbaalenii_PYR-1 DWLDTSHAFHSALLDPVLEEFESCADRFEFGTPQRTLVCNRSGEVLSRHA
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK TLDAAYWRRHARQPVEFAKSVHTLADMNCKLLVEIGPRPVLTAAALSAWP
Mvan_1003|M.vanbaalenii_PYR-1 RLDGQYWRRHARQPVRFAESVRTLADLGCRLLMEIGPQPVLTAAAMRTWP
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK DPATSPRVIASLRRTTADQRQITEAVADAYVLGHLPRFAAFRRDGARVLD
Mvan_1003|M.vanbaalenii_PYR-1 GTVTAPRVAASMRRKGSDRRQITEALAQAYVAGHRPETAARQHGRGRLLD
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK LPTYPFEHRQYWFSDSREPVAAAPQRGARTETVRLLEDGRIEELAALLGG
Mvan_1003|M.vanbaalenii_PYR-1 LPTYPFQHRAYWFPQGQ--ARTAPTDPVHTETVRFLDEERIDELAALLDG
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK TVDDPFTFDVLNRLAAQHNQQRSTESIADDRYQIRWETAAEPPVGADAAD
Mvan_1003|M.vanbaalenii_PYR-1 PTGSAQTVDVLSKLAARHRQQRGAQSIADARYQIRWEKSEAPGAARPTTE
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GITWLLVGDDTDATRPLVDVLAARGHRYRILGLPKSGAEEHELADTLRDA
Mvan_1003|M.vanbaalenii_PYR-1 ATTWLLVTHDSRAAQPIAEVLERRGHPYHIVGLPGSDADAAPAEEALR-A
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK AADATDLRIVHVAALDAAESDTSMKSLLRMQHRVLGGTRRLFGAAVAAQL
Mvan_1003|M.vanbaalenii_PYR-1 TVSQPRPHILYLAALEEPG-GSAAETLGWMQHRVLAAARRLFQLAATAGA
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK RSPMWLVTRGAQHVTDTDVVAPDQTCLWGFGRAASLEHPQIWGGLADLGG
Mvan_1003|M.vanbaalenii_PYR-1 RAPIWLITAGAQRITGDETVEPAQTSLWGFGRAAALEQPELWGGLADVTT
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GTSDEWSRLLNRIAATHDPAVMEDQVAVRGSTSYVPRLVHRDTLPSGKPL
Mvan_1003|M.vanbaalenii_PYR-1 GDAEEWSALIDHIVAAPT---SEDQIAVRGREIHVARLTRCAEKANAAAL
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK HLRADATYLVTGGLGSLGLEIAGYLAANGAGHLVLTSRRTPDEAAASRIE
Mvan_1003|M.vanbaalenii_PYR-1 ELRREATYLVTGGLGALGLEVAEFLASHGAGHLVLTGRRSASDTVRQRID
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK ALRERHGCEVRVVTADVADAHAVARLLATVQAEMPPLAGIVHAAGEIGTT
Mvan_1003|M.vanbaalenii_PYR-1 AMRERFDCQVLVATADVADRDDVARLFSTMRSELPPLAGIVHAAGEIGTS
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK PLADLDDAEVDRVFAGKVWGAWHLSEATSDLQLDFFISTSSIASVWGGFG
Mvan_1003|M.vanbaalenii_PYR-1 PLRTLDDAEMDRVFAGKVWGAVYLCEEVADMGLDFFLATSSIASVWGSHG
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK QAAYGAANAFLDGLAWRLREQGVAGVSVNFGPWSAGMADAQSRARLEQRG
Mvan_1003|M.vanbaalenii_PYR-1 QTAYGAANAFLDGLADSLRARGIPGISVNFGPWAAGMADAKAREQLSRRG
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK IKTLSPADALAGLSDAVISAAPHPVVARVDWSRFLPLYQQAGRRGFLAEL
Mvan_1003|M.vanbaalenii_PYR-1 VKTLAPADALAGMADVIAASTAHAVVARIDWATFLPVYQLQRRRAFLSQL
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK ERELPAAPAQQGPAVTASGRTPLVERLTTAPLQQRKRLLTDYLRDAVAEV
Mvan_1003|M.vanbaalenii_PYR-1 EREVPDVPDASAPAP--SGTTRFVEELTLAPVEQRRKLVLEYLRAAVAEV
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK TRVDAAEIREDAGFFDLGMDSLMAVELRRRIETGVGKEIPVTLVMDHPRL
Mvan_1003|M.vanbaalenii_PYR-1 TRVDAAEIRDEAGFFDLGMDSLMAIELRRRLEQGLGKELPVTLAMDHPHL
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 ---------------------------METSVTPIAVIGMGCRLPGGINS
MUL_2010|M.ulcerans_Agy99 ---------------------------MQKSATPVAIIGMGCRLPGGVDS
MMAR_2344|M.marinum_M --------------------------MAKSHVTPVAVIGMACRLPKGIDS
Mb3855c|M.bovis_AF2122/97 --------MGLGSAASGTGADRGAWTLAEPRVTPVAVIGMACRLPGGIDS
Rv3825c|M.tuberculosis_H37Rv --------MGLGSAASGTGADRGAWTLAEPRVTPVAVIGMACRLPGGIDS
MAV_2370|M.avium_104 -------------------------------MVPVAVIGMACRLPGAVDS
MSMEG_4727|M.smegmatis_MC2_155 --------------------------MTQNCVAPVAIIGMACRLPGAINS
TH_4621|M.thermoresistible__bu -----------------------VNIVGDTPVNAVAVIGMACRLPGGIDS
Mflv_0405|M.gilvum_PYR-GCK SDAADYLLGDVLGLTEAATAPKAATVVSTAADEPIAIVAVSCRFPG-APN
Mvan_1003|M.vanbaalenii_PYR-1 SDAAEYVLGDVLGLSEHTVA-QPDTPSTVRTDDPIAIVGMACRFPG-ADD
MAB_2212|M.abscessus_ATCC_1997 -------------------------------MVAVAIIGIGCRFPGGIGD
.:*::.:.**:* .
MLBr_00139|M.leprae_Br4923 PDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGRSVSRWGGFLDDV
MUL_2010|M.ulcerans_Agy99 PEKLWESLLRGDDLVSEIPPDRWDVDDYYDPEPGVPGRTVSRWGGFIDDV
MMAR_2344|M.marinum_M PEKFWTALLRGDDLITEIPADRWDADEYYDPEPGVPDHSVSRWGGFLDDV
Mb3855c|M.bovis_AF2122/97 PELLWKALLRGDDLITEVPPDRWDCDEFYDPQPGVPGRTVCKWGGFLDNP
Rv3825c|M.tuberculosis_H37Rv PELLWKALLRGDDLITEVPPDRWDCDEFYDPQPGVPGRTVCKWGGFLDNP
MAV_2370|M.avium_104 PERLWEALLRGDDFVTEIPPDRWDADEYYDPEPGVPGRSVSRWGAFIDDV
MSMEG_4727|M.smegmatis_MC2_155 PQQLWEALLRGDDFVTEIPTGRWDAEEYYDPEPGVPGRSVSKWGAFLDDP
TH_4621|M.thermoresistible__bu PQRLWEALLRGDDMVTEIPVDRWDADDYFDPEPGVPGRTVSRWGAFLDDV
Mflv_0405|M.gilvum_PYR-GCK PEAFWDLLSGGVDAIREVPEDRFDIDEFYDPDPDAAGKTYTRYGGFLDHI
Mvan_1003|M.vanbaalenii_PYR-1 TDAFWSVLAEGADLIREIPDDRFDINEFYDPDPEAAGKIYSRYGGFLDGV
MAB_2212|M.abscessus_ATCC_1997 ADSFWNFVLHKGDAVADIPKDRWDADKYYDPDPDTPGRMYTRRGSFLTQE
.: :* : : : ::* .*:* :.::**:* ...: : *.*:
MLBr_00139|M.leprae_Br4923 AG-FDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSSTA
MUL_2010|M.ulcerans_Agy99 AG-FDAEFFGVSEREATSIDPQHRQLLETAWEAIEHAGLDPASLSGSSTG
MMAR_2344|M.marinum_M AG-FDPEFFGISEREAIAIDPQHRLLLQTSWEAVEHAGMPPMSLSGSLTG
Mb3855c|M.bovis_AF2122/97 AD-FDCEFFGIGEREAIAIDPQQRLLLETSWEAMEHAGLTQQTLAGSATG
Rv3825c|M.tuberculosis_H37Rv AD-FDCEFFGIGEREAIAIDPQQRLLLETSWEAMEHAGLTQQTLAGSATG
MAV_2370|M.avium_104 AG-FDPEFFGINEREATAMDPQHRLLLETSWEAMEHAGLTEERVADSRTG
MSMEG_4727|M.smegmatis_MC2_155 AA-FDPEFFGITEREAAAIDPQHRLLLETAWEAVEHSGLNPAGLAGSATG
TH_4621|M.thermoresistible__bu AG-FDPEFFGISEREAISIDPQQRLLLETSWEAMEHAGLTPADVEGSSTG
Mflv_0405|M.gilvum_PYR-GCK DE-FDPEFFGLSPREAVWIEPQQRLMLETVWEGLERAGYAPSALRGSRTG
Mvan_1003|M.vanbaalenii_PYR-1 DG-FDPEFFGISPREAVWIDPQQRLVLETAWEGLERAGYSAAALRGSRSG
MAB_2212|M.abscessus_ATCC_1997 FRRFDADFFGISHREAAVLDPQQRLLLETTWEALDDAGIAGQAVGGNVGT
** :***: *** ::**:* :*:* **.:: .* : ..
MLBr_00139|M.leprae_Br4923 VFTGLTHEDYLVLT-TAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAM
MUL_2010|M.ulcerans_Agy99 VFVGLSHEDYLVRS-VLAGDLAGPYASTGLINSVASGRIAHTLGLHGPAM
MMAR_2344|M.marinum_M VFVGMCHDDYAFVT-DDAGALGDAYAFTGTAFSMASGRVSYALGLRGPAM
Mb3855c|M.bovis_AF2122/97 VFAGVTHGDYTMVA-ADAKQLEEPYGYLGNSFSMASGRVAYAMRLHGPAI
Rv3825c|M.tuberculosis_H37Rv VFAGVTHGDYTMVA-ADAKQLEEPYGYLGNSFSMASGRVAYAMRLHGPAI
MAV_2370|M.avium_104 VFIGLTHGDYQLLA-ADTRSVEGAYGFSGSNFSLASGRIAYALGVHGPAL
MSMEG_4727|M.smegmatis_MC2_155 VFMGLTHNDYAHLA-ADAKALEGPYGFTGTSFSLASGRIAYALGVHGPAI
TH_4621|M.thermoresistible__bu VFVGLSHDDYALLT-SDAGALEEAYGFTGSAFSMASGRIAYRLGVHGPAV
Mflv_0405|M.gilvum_PYR-GCK VFVGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGLEGPAV
Mvan_1003|M.vanbaalenii_PYR-1 VYVGVGANEYSHLLSGGSLDGIEAQFITGNALNVIAGRVSFTLGLEGPAV
MAB_2212|M.abscessus_ATCC_1997 FIGGFMNDNMISRGLARNLEKINNFAAFSASQTLLSNRIAHALDLWGPSM
. *. : . . :.*::. : : **::
MLBr_00139|M.leprae_Br4923 TFDTACSSGLMAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGM
MUL_2010|M.ulcerans_Agy99 TVDTACSSGLLTVHLACRSLHEGESDLALAGGCALLLEPNGSVSLSSQGM
MMAR_2344|M.marinum_M TVDTACSSSLLAVHMACRSLDGGESELALAGGCMLMLEPDVFSSASAQGM
Mb3855c|M.bovis_AF2122/97 TVDTACSSGLTAVHMACRSLHEGESDVALAGGVALMLEPRKAAAGSALGM
Rv3825c|M.tuberculosis_H37Rv TVDTACSSGLTAVHMACRSLHEGESDVALAGGVALMLEPRKAAAGSALGM
MAV_2370|M.avium_104 TVDTACSSGLTAIHLACRSLHEGESDLALAGGATLALDPRKFSAGSAEGM
MSMEG_4727|M.smegmatis_MC2_155 TVDTACSSSLSAIHMACRSLHDGESDVALAGGVSVLLEPRKAAGGSAAGM
TH_4621|M.thermoresistible__bu TVDTACSSSLLAVHMACRSLQVGESDLALAGGAMVMLEPRKYTSASGLGM
Mflv_0405|M.gilvum_PYR-GCK AVDTACSSSLVAVHQATQALRSGDCDMALAGGVNVLLSPVTVVAASRARM
Mvan_1003|M.vanbaalenii_PYR-1 AVDTACSSSLVAVHQACQGLQSGDCDLALAGGVNVLLSPATTIATSRARM
MAB_2212|M.abscessus_ATCC_1997 TVDTACSSSLVTTHLAVRAVANGECDVALAGGVNVMFQPETFITMCKGRF
:.******.* : * * :.: *:.::***** : :.* . :
MLBr_00139|M.leprae_Br4923 LSSTGRCKSFAADADGFVRSEGCAMVLLKRLPDALRDGNRIFAMILGTAT
MUL_2010|M.ulcerans_Agy99 LSPTGRCHAFDVDADGFVRSEGCAVVVLKRLSDALADGDRILAVVRGTAA
MMAR_2344|M.marinum_M LSPTGRCRTFDASADGFVRSEGCAMLVLKRLPDAVRDGDRVLAVLRGSAT
Mb3855c|M.bovis_AF2122/97 LSPTGRCRAFDVAADGFVSGEGCAVVVLKRLPDALADGDRILAVIRGTSA
Rv3825c|M.tuberculosis_H37Rv LSPTGRCRAFDVAADGFVSGEGCAVVVLKRLPDALADGDRILAVIRGTSA
MAV_2370|M.avium_104 LSPTGRCHAFDVAADGFVGGEGSVMLLLKRLNDALRDGDRILAVVRGTAA
MSMEG_4727|M.smegmatis_MC2_155 LSPTGHCHAFDTAADGFVSAEGCVVLTLKRLDDAVADGDRILAVIRGTAT
TH_4621|M.thermoresistible__bu LSPTGRCHAFDVAADGFVRSEGSVMLLLKRLPDALRDNDRILAVVRGTAA
Mflv_0405|M.gilvum_PYR-GCK LSPVGRCKTFDASADGYVRSEGCGILVLKRLSDAVRDGDRVCAVIAGSAV
Mvan_1003|M.vanbaalenii_PYR-1 LSPDGRCKTFDAAADGYVRGEGCGILVLKRLSDAVRDGDRIQAVIRGSAV
MAB_2212|M.abscessus_ATCC_1997 LAADGRSKSFDAAADGYGRGEGVGIVVLKNLEQAQRDGDHIYAVIRGSGV
*:. *:.::* . ***: .** :: **.* :* *.::: *:: *:..
MLBr_00139|M.leprae_Br4923 NQDGGTETLMMPSEDAQVAVYQAALAVAGVEPETIGVVEAHGTGTPIGDP
MUL_2010|M.ulcerans_Agy99 NQDGRSETLLMPSETAQVAVYREALAAAGVDAASVGAVEVHGTGTPVGDP
MMAR_2344|M.marinum_M NQDGRTDNISTPSPDAQVAAYRAALAVAGVDADTVGMIEAHGTGTPVGDP
Mb3855c|M.bovis_AF2122/97 NQDGHTVNIATPSQPAQVAAYRAALAAGGVDAATVGMVEAHGPGTPIGDP
Rv3825c|M.tuberculosis_H37Rv NQDGHTVNIATPSQPAQVAAYRAALAAGGVDAATVGMVEAHGPGTPIGDP
MAV_2370|M.avium_104 NQDGHTVNIATPSKTAQTAVYRAALAAAGVDAGTVGMVEAHGPGTPVGDP
MSMEG_4727|M.smegmatis_MC2_155 NQDGRTVNIATPSADAQAKVYRMALKAAGVEPGTVGLVEAHGTGTPVGDP
TH_4621|M.thermoresistible__bu NQDGRTENISTPSIQAQADVYRSALAVAGVDPATVGMVEAHGTGTPVGDP
Mflv_0405|M.gilvum_PYR-GCK NQDGASSGLTVPNGGAQQRLIGTVLARAGITGGEVDYLEAHGTGTPLGDP
Mvan_1003|M.vanbaalenii_PYR-1 NQDGASGGLTVPNGGAQQRVIAAALTRAGLSGSDIDYLEAHGTGTSLGDP
MAB_2212|M.abscessus_ATCC_1997 NQDGRTIALPVPNPVSQQRLADRVIKEAGIDPALVGYIEAHGTGTSVGDP
**** : : *. :* .: .*: :. :*.**.**.:***
MLBr_00139|M.leprae_Br4923 IEYRSLARVYGAG----TPCALGSAKSNMGHSTASAGTVGLIKAILSLRN
MUL_2010|M.ulcerans_Agy99 IEYRSLAQVYGSGG---SRCMLGSVKTNIGHSESAAGTVGLIKATLSLGH
MMAR_2344|M.marinum_M IEFSSLAQVYGSNG---NPCAVGSAKSSVGHTEAAAGAVGIIKAVLSLQH
Mb3855c|M.bovis_AF2122/97 IEYASVSEVYGVD----GPCALASVKTNFGHTQSTAGVLGLIKVVLALKH
Rv3825c|M.tuberculosis_H37Rv IEYASVSEVYGVD----GPCALASVKTNFGHTQSTAGVLGLIKVVLALKH
MAV_2370|M.avium_104 IEYASLAEVYGID----GPCALASVKTNFGHAQAASGALGMMKAILALQH
MSMEG_4727|M.smegmatis_MC2_155 LEFSSLAEVYGTD----GPCALGSIKTNFGHTQSAAGALGVMKAVLALQH
TH_4621|M.thermoresistible__bu IEYNSLTQVYGKT----GPCALTSVKTNFGHAESAAGALGMMKAILALQH
Mflv_0405|M.gilvum_PYR-GCK IEVQAAAAAYAGARDADRPLLMGSVKTNIGHTESASGAAGLIKVVLSLQH
Mvan_1003|M.vanbaalenii_PYR-1 IEVQAAGAVLGAGRDPDRPLLMGSVKTNVGHLESASGVAGLIKVVLSLQH
MAB_2212|M.abscessus_ATCC_1997 LEAQALGHSYGRVAGRARPLVIGSVKNNFGHTEAAAGVAGLIKAALTVQR
:* : . : * *...** :::*. *::*. *:: .
MLBr_00139|M.leprae_Br4923 GLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGM
MUL_2010|M.ulcerans_Agy99 GVVPPMVHHTRLPDELAEIETGLYVPHEITPWPED--QGPRRIAVSSFGM
MMAR_2344|M.marinum_M GLVPPMVHHTRLPDELAEIDSALFVPQAITPWPEGNDRTPRRAAVSSYGM
Mb3855c|M.bovis_AF2122/97 GVVPRNLHFTRLPDEIAGITTNLFVPEVTTPWPTNGRQVPRRAAVSSYGF
Rv3825c|M.tuberculosis_H37Rv GVVPRNLHFTRLPDEIAGITTNLFVPEVTTPWPTNGRQVPRRAAVSSYGF
MAV_2370|M.avium_104 GVVPRNLHFTQLPDDLARIDTKLFVPQQTTPWVSNGG-HPRRAAVSSYGL
MSMEG_4727|M.smegmatis_MC2_155 NVIPQNLHFTRLPDQMAEIETGLFVPETITPWPVREG-QPRRAAVSAYGL
TH_4621|M.thermoresistible__bu GVVPQNLHFTRLPDEMAAIETNLFVPQATTLWPVREG-CPRRAAVSSYGM
Mflv_0405|M.gilvum_PYR-GCK ETLPQSLHFDTPSPHIPWDSLPVRVVDTAMPWQPNGR--PRRAGVSSFGF
Mvan_1003|M.vanbaalenii_PYR-1 EMLPRHLHFKTPSPHIPWDRLAVRVVAEPTPWRADGR--PRRAGVSSFGF
MAB_2212|M.abscessus_ATCC_1997 RTIAPQVVLDKLNPEIPFDQLQIRIPTEVEPYPDLG--APAYAAVNSFGY
:. : .:. : : : * .*.::*
MLBr_00139|M.leprae_Br4923 SGTNVHVIVEEAPSEACAPDVPETSPGTGDA-------TVGRQLFMLSST
MUL_2010|M.ulcerans_Agy99 SGTNVHAILEEPPTPAPARDQASAEPG-----------MASPLLFALSST
MMAR_2344|M.marinum_M SGSNVHVILEQAPEPAVCRNGAAGLG--------------DALLFTVSAS
Mb3855c|M.bovis_AF2122/97 SGTNVHAVVEQAPQTEAQPHAASTPPTG------------TPALFTLSAS
Rv3825c|M.tuberculosis_H37Rv SGTNVHAVVEQAPQTEAQPHAASTPPTG------------TPALFTLSAS
MAV_2370|M.avium_104 SGTNVHAILEQAPEPAPETVAPEGISAE------------SPLLFPLSST
MSMEG_4727|M.smegmatis_MC2_155 SGTNVHAVLEQAPESPAETAAEAISPKAG-----------NALVFPVSAS
TH_4621|M.thermoresistible__bu SGTNVHAVLEQAPEPVQRPEESADTDAAG------------PLVFALSST
Mflv_0405|M.gilvum_PYR-GCK TGTNAHVLIEEAPTDLAGPTEPTAPAEPVDEDAAADPAPAPVEVLPLSAR
Mvan_1003|M.vanbaalenii_PYR-1 SGTNAHVVLEEPPAQSADLRQPPTDGKDGAAGLESATAPEPAGVLPISAR
MAB_2212|M.abscessus_ATCC_1997 GGTNAHVLVQEPPAPVQTEAPARDSIR----------------IFPVSAR
*:*.*.::::.* :: :*:
MLBr_00139|M.leprae_Br4923 SIAALRETARQLATWV------EEHQDSVVLSDLAYTLARGRAHRPVRTA
MUL_2010|M.ulcerans_Agy99 SADGLRQTARELAEWVGSR---ADSADSTEAVDLAYTLARRRAHRPVRTA
MMAR_2344|M.marinum_M STEALRQTADRLADWV--------DNHEISPSDLAYTLARRRSHQPVRAG
Mb3855c|M.bovis_AF2122/97 SADALRQTAQRLTDWIQ------QHADSLVLSDLAYTLARRRTHRSVRTA
Rv3825c|M.tuberculosis_H37Rv SADALRQTAQRLTDWIQ------QHADSLVLSDLAYTLARRRTHRSVRTA
MAV_2370|M.avium_104 SADELRRTAGRLADWVH------AHGD-LALPDLAYTLARRRVHRPVRTA
MSMEG_4727|M.smegmatis_MC2_155 SADALRSTAQHLADWLLRSGDGNGRGPAIDLGDLAYTLARRRGFRAARSA
TH_4621|M.thermoresistible__bu SAEELRRTAGRLAEWVE------AHTDEVVPADLAYTLARRRAHRPVRTT
Mflv_0405|M.gilvum_PYR-GCK SPEALVALAQRYETWLT-------AHPEADLADVCRTAGTGRSHFEHRAA
Mvan_1003|M.vanbaalenii_PYR-1 SPEALTALARRYESWLT-------AHPDADIADVCYTAGAGRSHFEHRAA
MAB_2212|M.abscessus_ATCC_1997 SGSALHEVAGRYAKQLS------SDLSQDGAQRLKTAATARRAQHYLRKG
* * * . : : : * *
MLBr_00139|M.leprae_Br4923 VVAADLPELVEGLCEIADGDALYDAVVGHGDRGP--VWVFSGQGSQWASM
MUL_2010|M.ulcerans_Agy99 VVAASLPELVEGLQEVAEGDLVYEAAVGRGDRGP--VWVFSGQGSQWAAM
MMAR_2344|M.marinum_M LVAGNRTELAHRLRETAAGDTPYPAAVGHDDLGP--VWVFSGQGSQWATM
Mb3855c|M.bovis_AF2122/97 VIASSVDELIAGLGEVADGDTVYQPAVGQDDRGP--VWLFSGQGSQWAAM
Rv3825c|M.tuberculosis_H37Rv VIASSVDELIAGLGEVADGDTVYQPAVGQDDRGP--VWLFSGQGSQWAAM
MAV_2370|M.avium_104 VLAGDRAQLIEALREVADGDTPYPAAVGRGDRGP--VWVFSGQGSQWAAM
MSMEG_4727|M.smegmatis_MC2_155 VLAGDRGTLVEGLRQIADGEAMPQQAVTNDDRGP--VWVFSGQGSQWASM
TH_4621|M.thermoresistible__bu VIADGVEALTAGLREVADGDAPYQPAVGMDDKAP--VWVFSGQGSQWAGM
Mflv_0405|M.gilvum_PYR-GCK LVVDSVESARIALTDLAQNRLRPGVVRGEHLNHPTTAWMFTGQGSQYPGM
Mvan_1003|M.vanbaalenii_PYR-1 LVVDSVDGARDLLAGLAEDRLGPGAVRGVCGDPPKTAWLFTGQGSQYPGM
MAB_2212|M.abscessus_ATCC_1997 FIYRDADDLLAQLNTYAASDEAAPPRALVEGISDP-VFVFSGMGPQWWGM
.: . * * . .::*:* *.*: *
MLBr_00139|M.leprae_Br4923 GVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGI-------
MUL_2010|M.ulcerans_Agy99 GADLLANEPVFAATVAAVEPIIAHESGFSVTEAMTAPEKVTGI-------
MMAR_2344|M.marinum_M GADLLANEPVFAATVAELEPLIAAESGFSVTEAMTAMEPVTGI-------
Mb3855c|M.bovis_AF2122/97 GADLLTNESVFAATVAELEPLIAAESGFSVTEAMTAPETVTGI-------
Rv3825c|M.tuberculosis_H37Rv GADLLTNESVFAATVAELEPLIAAESGFSVTEAMTAPETVTGI-------
MAV_2370|M.avium_104 GADLLATEPVFAATVAQAEPLIARESGFSVAEAMSAPQTVTGQ-------
MSMEG_4727|M.smegmatis_MC2_155 GAELLDREPAFAAAIAELEPLIAAESDFSVTEALTASETVTGI-------
TH_4621|M.thermoresistible__bu GAELLATEQVFAAKIAEIEPLVARESGFSVTEAMTASETVTGI-------
Mflv_0405|M.gilvum_PYR-GCK ARELFDTEPVFADTVTRCADAVADLLPRPLLDVMFAGGREAGVPPTETLR
Mvan_1003|M.vanbaalenii_PYR-1 ARELFDTEPVFRDTVTRCAEAIGDTLPRPLLEVLFDTDGDNGQ----TLR
MAB_2212|M.abscessus_ATCC_1997 ARALLERPGIFRDAAAEIDEVFQEISGWSVIAELLRPQADSRVSR-----
. *: * : . .: :
MLBr_00139|M.leprae_Br4923 --DKVQPSVFAVQVALATTMEQTYGVRPGAVIGHSMGESAAAVVAGALSL
MUL_2010|M.ulcerans_Agy99 --DKVQPTLFAMQVALAATMEKTYGVRPGAVIGHSLGEAAAAVVAGSLSL
MMAR_2344|M.marinum_M --DRVQPTLFAIQVALAQTMR-SYGVHPGAVIGHSLGEVAAAVVAGALLL
Mb3855c|M.bovis_AF2122/97 --DRVQPTIFAMQVALAATMA-AYGVRPGAVIGHSMGESAAAVVAGVLSA
Rv3825c|M.tuberculosis_H37Rv --DRVQPTIFAMQVALAATMA-AYGVRPGAVIGHSMGESAAAVVAGVLSA
MAV_2370|M.avium_104 --DRVQPTLFTMQVALAATMK-AHGVRPGAVIGHSLGEAAAAVVAGALSL
MSMEG_4727|M.smegmatis_MC2_155 --DRVQPTIFAVQVALAAAMR-SHGVVPGAVIGHSMGEVAASVVSGALSL
TH_4621|M.thermoresistible__bu --DRVQPTLFAIQVALAATMQ-SYGVRPGAVIGHSLGEVAAAVVAGALSL
Mflv_0405|M.gilvum_PYR-GCK HTSFAQPALFAVEMGLARLWQ-SWGIVPDVVLGHSVGQYAAACVAGVFSL
Mvan_1003|M.vanbaalenii_PYR-1 HTSYAQPALFAIEMGLARLWQ-ARGIEPDVVLGHSVGQYAAACVAGVFGL
MAB_2212|M.abscessus_ATCC_1997 -TEIAQPANFLVQSALAKHLQ-QFGIRPTAVVGHSVGEVAAAYVSGALSL
. .**: * :: .** *: * .*:***:*: **: *:* :
MLBr_00139|M.leprae_Br4923 EDAARVICRRSKLMNRVAGSGAMGSVELPAKQVNSELMARGIDDVVISVV
MUL_2010|M.ulcerans_Agy99 EDGARVISRRSKLMLRISGAGAMASVELPAKQVNSELMARGIDDVAVAVV
MMAR_2344|M.marinum_M ADGVKVICRRSRLCTRLAGSGAMASVELPAARVREDLVRHRAKDVVVAVV
Mb3855c|M.bovis_AF2122/97 EDGVRVICRRSKLMATIAGSAAMASVELPALAVQSELTALGIDDVVVAVV
Rv3825c|M.tuberculosis_H37Rv EDGVRVICRRSKLMATIAGSAAMASVELPALAVQSELTALGIDDVVVAVV
MAV_2370|M.avium_104 EDGARVICRRSRLMSRVAGTGATASVELPAQQVLSELTARGISDVVVAVV
MSMEG_4727|M.smegmatis_MC2_155 EDGVKVICRRTRLMTRIAGSGAMAMVELPAQQVLSELASRGVDDVVLSVV
TH_4621|M.thermoresistible__bu EDGVKVICRRSRLCLRLAGAGAMAAIELPAQAVREFLAARGVDDVVLSVI
Mflv_0405|M.gilvum_PYR-GCK EDGARLMAERGRLFGSLPEGGRMVAVFADAKRVEQVAADFPRVSVGAYNG
Mvan_1003|M.vanbaalenii_PYR-1 EDGARLVADRGRLFGGLPVGGRMVAVFTDAEVVEDFADEFPQVSVAAYNG
MAB_2212|M.abscessus_ATCC_1997 RDAATVSFHRSRLQAKTAGSGGMLAVGLDAEEAQRRAARFG-SAVCVAAI
*.. : * :* . . : * . *
MLBr_00139|M.leprae_Br4923 ASPQSTVIGGATETVRDLIAQWEQRDVMAREVAVDVASHSSQVDPILDDL
MUL_2010|M.ulcerans_Agy99 ASPQSTVVGGATDTVRDLVARWEQREVMAREVAVDVASHSPQVDPILEDL
MMAR_2344|M.marinum_M ASPQSTVIGGATDTVRELVAAWGEREVMAREVAVDVASHTPQVEPILGEL
Mb3855c|M.bovis_AF2122/97 TAPQSTVIAGGTESVRKLVDIWERRDVLARAVAVDVASHSPQVDPILDEL
Rv3825c|M.tuberculosis_H37Rv TAPQSTVIAGGTESVRKLVDIWERRDVLARAVAVDVASHSPQVDPILDEL
MAV_2370|M.avium_104 ASPQSTVIAGAAPTVRDLVTAWQERGVMAREVPTDVAFHSPQVDPIMDDL
MSMEG_4727|M.smegmatis_MC2_155 ASPQSTVVGGATASVRELIEMWESRGVMAREIAVDVASHSPQVDPILDDL
TH_4621|M.thermoresistible__bu ASPESTVIGGATDTVRELVAAWEAQGVMAREVAVDVASHSPQVDPILDEL
Mflv_0405|M.gilvum_PYR-GCK P---NTVLSGPGEDLEQIVGTFGEDGIRCTWLETSHAFHSELLDPVLDEF
Mvan_1003|M.vanbaalenii_PYR-1 P---NTVLAGPASDLEQIVAGCSGEGIRTTWLDTSHAFHSALLDPVLDEF
MAB_2212|M.abscessus_ATCC_1997 NSTAATTLSGDSAALQTLHDELAGDGIFARMLHVEVPYHSQLMDPILGEL
*.:.* :. : : : .. . *: ::*:: ::
MLBr_00139|M.leprae_Br4923 AAALADIAPMTPKVPYYS-ATLFDPRELPVCNGAYWVDNLRNTVQFAAAV
MUL_2010|M.ulcerans_Agy99 ATALADIVPSDPKVPYYS-ATLFDPRERPTCDAAYWVDNLRNTVQFAAAV
MMAR_2344|M.marinum_M SELLADVEPLAPQLPYYS-ATSFDPRERPRCDARYWVDNLRHAVRFSAAV
Mb3855c|M.bovis_AF2122/97 IAALADLNPKAPEIPYYS-ATLFDPREAPACDARYWADNLRHTVRFSAAV
Rv3825c|M.tuberculosis_H37Rv IAALADLNPKAPEIPYYS-ATLFDPREAPACDARYWADNLRHTVRFSAAV
MAV_2370|M.avium_104 TDALAEISPRPPEVPYYS-ATLFDPREQPVCDARYWANNMRRMVRFATAV
MSMEG_4727|M.smegmatis_MC2_155 IEALADLDPAEPEIPYYS-ATLYDPRDYADYDAYYWADNLRHTVRFSAAV
TH_4621|M.thermoresistible__bu EEILADLQPMTPTVPYYS-ATSYDPREKPVCDADYWVDNLRHEVRFAAAV
Mflv_0405|M.gilvum_PYR-GCK ESYAAQLQFAAPTLPLVCNRTGAVLTGQTSLDAQYWRRHSRQPVQFAESV
Mvan_1003|M.vanbaalenii_PYR-1 ESCAARLAYAAPTRPLVCNRTGAVVTGPGVIDAQYWRRHARQPVQFAESV
MAB_2212|M.abscessus_ATCC_1997 ATALAGLTPRKAAVPVYSTVTGEKMHSAAFAEPDYWCKNVRDSVLFAKAV
* : . * . * : ** : * * *: :*
MLBr_00139|M.leprae_Br4923 QAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMPYG
MUL_2010|M.ulcerans_Agy99 QAALEDGFRVFAELSPHPLLTHAVDQNARSLDMSAAVLAGMRREQPLPHG
MMAR_2344|M.marinum_M RAALDDGYRVFGELSPHPLLTRAVEQTAASLDIPAAALPAMRRNQPLPHG
Mb3855c|M.bovis_AF2122/97 RSALDDGYRVFAELSPHPLLTHAVDQIAGSVGMPVAALAGMRREQPLPLG
Rv3825c|M.tuberculosis_H37Rv RSALDDGYRVFAELSPHPLLTHAVDQIAGSVGMPVAALAGMRREQPLPLG
MAV_2370|M.avium_104 QAALEDGYRVFAELAPHPLLVRALEQTARSREIPMAALAGMRRGQALPHG
MSMEG_4727|M.smegmatis_MC2_155 QAALEDGHRVFAELSPHPLLTHPVEQTARSLDMPLAVFAAMRRQQEMPHG
TH_4621|M.thermoresistible__bu QAALEDGFRVFGELSPHPLLTRAVEQTARGLDMPVAALPAMRREQEMPHG
Mflv_0405|M.gilvum_PYR-GCK RTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAAPRAIASLRKGVADRRQ
Mvan_1003|M.vanbaalenii_PYR-1 RTLADLGCSVLMEIGPQPFLIAAALRVWPESAATPRAIPSLRKGPDARRQ
MAB_2212|M.abscessus_ATCC_1997 DTLIVDRYRVFLELGPHPVLLGNIRESFVRHSVSGAAIQTLHRDQDDEQS
: *: *:.*:*.* . . .: :::
MLBr_00139|M.leprae_Br4923 LRGLLADLHSAG--AALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQ
MUL_2010|M.ulcerans_Agy99 LRGLLTDVHSAG--AAVDFSVLYPAGRLVNAPPPAWTHRRFFVDGEGQDS
MMAR_2344|M.marinum_M LRGLVADLHSAG--AAVDFATLYPDGQLVDAPLPVWANRRLLLAT-ADAR
Mb3855c|M.bovis_AF2122/97 LRRLLTDLHNAG--AAVDFSVLCPQGRLVDAPLPAWSHRFLFYDREGVDN
Rv3825c|M.tuberculosis_H37Rv LRRLLTDLHNAG--AAVDFSVLCPQGRLVDAPLPAWSHRFLFYDREGVDN
MAV_2370|M.avium_104 LRGFVADLHNAG--AAVDFSVLYPTGRLVDAPLPTWTHRRLWLTDGGLES
MSMEG_4727|M.smegmatis_MC2_155 LLGFVADLHSAG--AAVDFSVLYPTGRLLDAPLPAWTHSTLLLDR-ELES
TH_4621|M.thermoresistible__bu VRTMVGDLFAAG--AAVDFAALYPSGRLVDAPLPTWTRRKLVLSRENGEQ
Mflv_0405|M.gilvum_PYR-GCK IADALAAAYIGG--HKPDFAALHEQRGVRLELPTYPFQRRRFWPKSAGMA
Mvan_1003|M.vanbaalenii_PYR-1 LAEAVAAAYIAG--HRLDFTGHDGGPHRRLPLPTYPFQHRSYWPKTAGIR
MAB_2212|M.abscessus_ATCC_1997 VLQAIADLYAVGAIDAPGQADIYESGVVPHMDLPKYPWSQEEVWEEDPLT
: : . * . : .
MLBr_00139|M.leprae_Br4923 RAQGACTVTVHPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVA
MUL_2010|M.ulcerans_Agy99 KAQGACSVTVHPLLGAHVRLSEQPERHVWQTDVGTDTLSWLSDHQVRNVA
MMAR_2344|M.marinum_M RHGCANSVAAHPLLGAHVDLLEEPERHAWQSEIGTATLPWLGDHQVNSVA
Mb3855c|M.bovis_AF2122/97 RSPGGSTVAVHPLLGAHVRLPEEPERHAWQADVGTATLPWLGDHRIHNVA
Rv3825c|M.tuberculosis_H37Rv RSPGGSTVAVHPLLGAHVRLPEEPERHAWQADVGTATLPWLGDHRIHNVA
MAV_2370|M.avium_104 PTHGGCTVAVHPLLGPHVHLQEEPERHLWQADVGTAAQPWLADHQIRNVV
MSMEG_4727|M.smegmatis_MC2_155 SAPGVPSVSVHPLLGSHVVLPQEPEEHLWQGDVGTEAHPWLSDHRVHQVA
TH_4621|M.thermoresistible__bu QTRGGCTITVHPLLGTHVRLPEEPERHVWQADLGTGAQPWLADHQIHTVA
Mflv_0405|M.gilvum_PYR-GCK IDGRVGASAGSGILGSGKDLASG--DSVYTSRLSVKTQPWLSDHVIYGTV
Mvan_1003|M.vanbaalenii_PYR-1 SDG----SSGSGLLGSAQDLASG--DIVHTSRLSVKTQPWLSDHVIYGTV
MAB_2212|M.abscessus_ATCC_1997 LRARYGDADRFALLGDRVDALTP----QWEVTLAPANLPWLPDHTVLGSV
:** :. .** ** : .
MLBr_00139|M.leprae_Br4923 ALPGAAYCEMALAAAVEVFG-EAAEVRAIAFEQMLLLAAETPIDAIASVD
MUL_2010|M.ulcerans_Agy99 ALPGAAYCEMALAAAGEVFG-EAFEVRDLAFEQMLLLDEETPIDAVASLD
MMAR_2344|M.marinum_M ALPGAAYCEMALAAANTVFG-NPSEVGDIGFHEMLLLDDQTAAGAVALVE
Mb3855c|M.bovis_AF2122/97 ALPGAAYCEMALSAARAVLG-EQSEVRDMRFEAMLLLDDQTPVSTVATVT
Rv3825c|M.tuberculosis_H37Rv ALPGAAYCEMALSAARAVLG-EQSEVRDMRFEAMLLLDDQTPVSTVATVT
MAV_2370|M.avium_104 VLPGAAYCEMALAAARSVLG-ATAEVRDIRFEQALLLDEQTTVDASASVS
MSMEG_4727|M.smegmatis_MC2_155 VLPGAAYCEMALAAVTPVLG-DTGEVHDLKFHDMLLLDDATPVWVSAAVT
TH_4621|M.thermoresistible__bu ALPGAAYCEMALAAAREVIDSDGVEVRDVRFEQMLLLDEQTEVSAVASAV
Mflv_0405|M.gilvum_PYR-GCK VVPGATYAAMALAAVGTPAHAKDVFFYEPIILPEKSSREVQLTVHPSVDG
Mvan_1003|M.vanbaalenii_PYR-1 VVPGATYAAMALAAMPTPARVQEVFFYEPIILGDKDSREVQLMLHRTDDA
MAB_2212|M.abscessus_ATCC_1997 VLPGTAYLDAALSAVRQRSGRAQAGLDSVVFAVPLVVADHDAPITRITVD
.:**::* **:* . :
MLBr_00139|M.leprae_Br4923 APGVINFVVQANQD--GEKMRNATATLHAAEDDCPPPAYDIAALLEAHPN
MUL_2010|M.ulcerans_Agy99 SPGAANFVVQTHVD--GETTRHATAALRASDDESVPPAYDIAALLAAHPV
MMAR_2344|M.marinum_M APGIASFAVDTVRG--GEKVRRSTALLRAVERDSQPAGYDIEALLAAHAC
Mb3855c|M.bovis_AF2122/97 SPGVVDFAVEALQEGVGHHLRRASAVLQQVSGECEPPAYDMASLLEAHPC
Rv3825c|M.tuberculosis_H37Rv SPGVVDFAVEALQEGVGHHLRRASAVLQQVSGECEPPAYDMASLLEAHPC
MAV_2370|M.avium_104 SPGVLHFTVQSHQG--GEQARHASAVLGAATDE-QPAAHDLSALLTAHPH
MSMEG_4727|M.smegmatis_MC2_155 APGTAEFGVETHQS--GDRTQRATAVLRGDVDAERPAAHSIDALLAAHPN
TH_4621|M.thermoresistible__bu EPGTLEFAVETAKD--GEHERRATAVLGAADDTEPPQAHDIDALLAEHPT
Mflv_0405|M.gilvum_PYR-GCK E-SKFQVHSRPYGERGAEWALNAEGVVASGVGDSPAAAGDLEDPVDEAIE
Mvan_1003|M.vanbaalenii_PYR-1 DGWTFEVHSRPYGDRDADWSRNASGTVAAGVGD--AAPDAAADPVDNAIE
MAB_2212|M.abscessus_ATCC_1997 EPTKRFTVNGRSAH-----TQLWTAHANGRLVEANLGSKRIDVSAWSAND
.
MLBr_00139|M.leprae_Br4923 SVN---GTDLRESFAERGVQLGAAFAGLATAHTAEAESGTVLAEVALPAS
MUL_2010|M.ulcerans_Agy99 SVN---GAELREAFVERGIQHGPAFSGLAIARTAETEGGTVLAEVALPAS
MMAR_2344|M.marinum_M RLD---GDELREWFAKTGIHYGPAFTGLAAAHVCERGSDAVLAEISLPGS
Mb3855c|M.bovis_AF2122/97 RVD---GEDLRRQFDKHGVQYGPAFTGLAVAYVAEDATATMLAEVALPGS
Rv3825c|M.tuberculosis_H37Rv RVD---GEDLRRQFDKHGVQYGPAFTGLAVAYVAEDATATMLAEVALPGS
MAV_2370|M.avium_104 DDD---GDEVRRRMDRRGVQYGPAFAGLGAVHSGDE-TGTVLAEVALPRQ
MSMEG_4727|M.smegmatis_MC2_155 RVD---GDELRAGFGTVGIGHGAAFAGLSEAYVATAAEPTVVAAVALPGP
TH_4621|M.thermoresistible__bu RIE---GDELRQWFDQRGVQFGPAFTGLTAARIPEGTVTSVLAEVGLPGQ
Mflv_0405|M.gilvum_PYR-GCK RLNRMRPQELFETFADLELAWGPTWS--GSLKSLWLGEGEAIGDILVGAE
Mvan_1003|M.vanbaalenii_PYR-1 RLTRTRPQQLFDAFADNDLAWGPAWC--SSLRSLWVGTGEAVGDIAVGAE
MAB_2212|M.abscessus_ATCC_1997 RVFD--GEDVYKGLSAVGLSYGPAFQRIQSVR---IGSAGCVAQLASPES
:: : : *.:: :. :
MLBr_00139|M.leprae_Br4923 IRFQQSSYQIHPALLDACFQSVGAGVDATKVGSR----AGLLLPLGVRSL
MUL_2010|M.ulcerans_Agy99 IRFQQGAYGVHPALLDACFQSVAAGVKSTGGG-------GLLLPLGVRSL
MMAR_2344|M.marinum_M MRTQQAGYLVHPALLDACFQSVLAHPVVREMGN-----GGLLLPLGVRRL
Mb3855c|M.bovis_AF2122/97 IRSQQGLYAIHPALLDACFQSVGAHPDSQSVGS-----GLL-VPLGVRRV
Rv3825c|M.tuberculosis_H37Rv IRSQQGLYAIHPALLDACFQSVGAHPDSQSVGS-----GLL-VPLGVRRV
MAV_2370|M.avium_104 IRSQQAAYGAHPALLDACFQSVEAHPAVRALGD-----GALGLVLGIRRL
MSMEG_4727|M.smegmatis_MC2_155 LRSGQRGYTVHPALLDACFQSVIAHPEVQNIAS------GMLLPLGVRRL
TH_4621|M.thermoresistible__bu IRSQQAPYGIHPALLDACFQSVAAHPDVQGAGS------GLLLPLGVRRL
Mflv_0405|M.gilvum_PYR-GCK LAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLYLPLRYGQVSL
Mvan_1003|M.vanbaalenii_PYR-1 LGEHLGREPIHPVLLDLCTGIAGAALLAAAAQTDADPELFLPLRYGRVEV
MAB_2212|M.abscessus_ATCC_1997 VSAQR--HAVHPALADAALQCIAVLLAARPELDIP---PTAHVPASIDRV
: **.* * . : . :
MLBr_00139|M.leprae_Br4923 RVYRPTRNARYCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGT
MUL_2010|M.ulcerans_Agy99 RAYGPTRNAQYCYTRVTKADANGGEADLELLDEQGCVLLAVRGLRLGTGT
MMAR_2344|M.marinum_M RSHASTRNARFCYTRVTACG-HDAEADIDVLDEHGTVLLAVRGLLMGTGL
Mb3855c|M.bovis_AF2122/97 RAYAPVRTARYCYTRVTKVELVGVEADIDVLDAHGTVLLAVCGLRIGTGV
Rv3825c|M.tuberculosis_H37Rv RAYAPVRTARYCYTRVTKVELVGVEADIDVLDAHGTVLLAVCGLRIGTGV
MAV_2370|M.avium_104 RAYGAARNAHYCYTRVTKADTSGVEADIDVLDEHGAVLLAVQGLRVGTSA
MSMEG_4727|M.smegmatis_MC2_155 RAYGSTRNVRYCLSRIVKADSFGVEADLELLDADGTVLLSAMGLQLGTGN
TH_4621|M.thermoresistible__bu QAFGPTRGARYCYARVTDADGSKAEADLDVLDEHGNVLLRVQGLLMGGAA
Mflv_0405|M.gilvum_PYR-GCK QEKMPRRFYCRATWHEAPLDSETQVFDLEYLDRDGRHLGGVREFTVKRAP
Mvan_1003|M.vanbaalenii_PYR-1 RERMPRRFYCRARWQTGGIDSETQVFDLDFLDHDGRNLGGIREFTVKRAP
MAB_2212|M.abscessus_ATCC_1997 RLYGEVPEDPVAVVEITSTQPLCANAYLASRDGEVALAMTGVTLRPVGSA
: . . : * . : .
MLBr_00139|M.leprae_Br4923 TERGEL--DRQLSERLLTIGWQQRTLPESV---HVEPGSWLLIDTFNASA
MUL_2010|M.ulcerans_Agy99 SESGER--DRVLSERLLTLEWQQRQLPEVL---DEETGSWLLIS---ASD
MMAR_2344|M.marinum_M SELADQ--DRLMSRHLLGTEWQQRELPQPQ---APNPESWLLVG---ISE
Mb3855c|M.bovis_AF2122/97 SERDKH--NRVLNERLLTIEWHQRELPEMD---PSGAGKWLLIS---DCA
Rv3825c|M.tuberculosis_H37Rv SERDKH--NRVLNERLLTIEWHQRELPEMD---PSGAGKWLLIS---DCA
MAV_2370|M.avium_104 SESGTR--DRVLTERLLNIEWRQRELPEPE---HADAASWLLIG---TTA
MSMEG_4727|M.smegmatis_MC2_155 SDKAEE--ERLLDERLLTIEWQQRELPRPEGSETVDAGSWLVILAG--DD
TH_4621|M.thermoresistible__bu ADGDDR--DRVLGERLLTIEWQRRDLPEAD----SAAGKWLLVS---TSA
Mflv_0405|M.gilvum_PYR-GCK REALLRGLGGDATRLLYTLGWHEVPVPESGDGAA-PQGTWLIGG------
Mvan_1003|M.vanbaalenii_PYR-1 REALLRGLGADATRLIYRVGWRETSPPVRDDGALGPSSTWLVAG------
MAB_2212|M.abscessus_ATCC_1997 STPLSELEQYFYEPRWEPLEEEIEGQPAPTTTAPAARPANVIVE------
. * ::
MLBr_00139|M.leprae_Br4923 IPDMWASTLTDALKSY-GTQGTECTNLSWLIQDDPVVSRERLGRQLRGRD
MUL_2010|M.ulcerans_Agy99 GEDLMATTLADALKS----QGAECASMVWSAQDDLAGGIEKLGAQLRART
MMAR_2344|M.marinum_M TADRLTTRLAEALKS----LGTDCITTSWHLQADHITDAERFRDQLRDHR
Mb3855c|M.bovis_AF2122/97 ASDVTATRLADAFRE----HSAACTTMRWPLHDDQLAAADQLRDQVGSDE
Rv3825c|M.tuberculosis_H37Rv ASDVTATRLADAFRE----HSAACTTMRWPLHDDQLAAADQLRDQVGSDE
MAV_2370|M.avium_104 TADVLASTLADTLKN----HGAQCTTMAWPQQADHTAHAEQLRNQWRGDG
MSMEG_4727|M.smegmatis_MC2_155 DENPRAAGVVSALIG----AGMPTTTMAWSHDADHDAQAAALTARLDEQP
TH_4621|M.thermoresistible__bu TADVSATRLSDALKQ----AGAESTSMCWPQQADHADNVDRFRAGI-ADG
Mflv_0405|M.gilvum_PYR-GCK -FDELAVSVPGCIPA----------------DRTNPESLRQLLTDAHGRG
Mvan_1003|M.vanbaalenii_PYR-1 -LDALADDVPGSIRIGFDRIWDPDRDGRVVLDPADDEHWRRLFALADERR
MAB_2212|M.abscessus_ATCC_1997 -IAQVPLAVAEGARR----AAAAGVVVLNADTVEKANLAVTFAEALDRDE
. : :
MLBr_00139|M.leprae_Br4923 --GVVILCGPRAGAPDEQSL----LAAREQVRHLVRIIRELAELEGELPR
MUL_2010|M.ulcerans_Agy99 NKGVVIVCGPRSGDADEQSL----LQGREQVRHLVRITRGLAELEGELPR
MMAR_2344|M.marinum_M FAGVVVMTGTGCSSP----------VTSDYVRHVVRVVRELPEIMGEAPR
Mb3855c|M.bovis_AF2122/97 FSGVVVLTGSNTGTPHQGSA----DRGAEYVRRLVGIARELSDLPGAVPR
Rv3825c|M.tuberculosis_H37Rv FSGVVVLTGSNTGTPHQGSA----DRGAEYVRRLVGIARELSDLPGAVPR
MAV_2370|M.avium_104 FTGVVVLTGPKNGDNDQESA----LLSRDHVQHLVRIARELTDLPGEPPR
MSMEG_4727|M.smegmatis_MC2_155 LAGVAVIVGDSETGTDAHDVGADARRGADHVRHLVRIARTLADAVGEPPR
TH_4621|M.thermoresistible__bu VTGVVVLTGPKNGNPDDAAAR----RGSDYVRHLVRITRELAEIDGDAPR
Mflv_0405|M.gilvum_PYR-GCK LPFSGVVWRAA-RSDGDESDAEVAARLEAEIAELLGAVHTVQGGEVKLPG
Mvan_1003|M.vanbaalenii_PYR-1 APVAGVVLGVTGRARPEEPSADFAARLEAQIRDVLGAVHSLSALGAKPAA
MAB_2212|M.abscessus_ATCC_1997 FLRVLVTVGSGKSAVENVAG---LVTVAQSLRMVMEAETERGVVSPDVQA
: : ::
MLBr_00139|M.leprae_Br4923 -LFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHT
MUL_2010|M.ulcerans_Agy99 -LFVVTRQAQRVRPEDEINLEQAGLRGLLRVIGSEHPLLQTTQVDVDEST
MMAR_2344|M.marinum_M -LFVVTRGAQTVLGGESANLEQAGLRGLLRVIGAEYPHLHTTHVDVDEHS
Mb3855c|M.bovis_AF2122/97 -MYVVTRGAQRVLADDCVNLEQGGLRGLLRTIGAEHPHLRATQIDVDEQT
Rv3825c|M.tuberculosis_H37Rv -MYVVTRGAQRVLADDCVNLEQGGLRGLLRTIGAEHPHLRATQIDVDEQT
MAV_2370|M.avium_104 -LYVVTRNAQTVLPNDVPNLGQAGLRGLVRVIGMEHPQLGAGQIDVDEST
MSMEG_4727|M.smegmatis_MC2_155 -LYVVTHRSQHVLDTDEPYLEHSGLRGLIRVVGMEHPRLRATQIDVDDST
TH_4621|M.thermoresistible__bu -LFVVTRGAQAVLPQDRPNLEQAGLRGLLRVIGAEHPHLRTTQIDIADDA
Mflv_0405|M.gilvum_PYR-GCK GLWIVTERAVATESGEPVDPVQAALWGFGRTAINEEPALRCRLVDCDGSP
Mvan_1003|M.vanbaalenii_PYR-1 GLWIVTERAVAAEAGEPVDPVQSALWGLGRTLIAEEPGLRCLLVDLDGSE
MAB_2212|M.abscessus_ATCC_1997 --VLVSKNAFLAPGDRDLDLDQAALVGARRVLANEQHPAKWSLVDLPAAV
:*:. : . :..* * *. * :*
MLBr_00139|M.leprae_Br4923 DVERVAQQLLSGS-EEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEH
MUL_2010|M.ulcerans_Agy99 QAEQLAQQLLGGS-EEDETAWRGGEWYVARLFPGPLSADERQTTVVDHER
MMAR_2344|M.marinum_M GSEVVARQLLSGS-EEDETAWRCGQWYTARLSPMPLRPEERKTTVVEHDT
Mb3855c|M.bovis_AF2122/97 GVEQLARQLLATS-EEDETAWRDNEWYVARLCPTPLRPQERRTIVADHQQ
Rv3825c|M.tuberculosis_H37Rv GVEQLARQLLATS-EEDETAWRDNEWYVARLCPTPLRPQERRTIVADHQQ
MAV_2370|M.avium_104 DAQALARQLLAGS-EEDETAWRDGAWYTARLCPAPLLPEERHTAVANHEC
MSMEG_4727|M.smegmatis_MC2_155 AHEALVRQLLSGS-PEDETAWRDGQWYAARLCPSPLRAAERRTAVADNAS
TH_4621|M.thermoresistible__bu DLDRVAVQLLGGG-AEDETAWRDGQWYTARLSLSPLRPEERKQAVVDCER
Mflv_0405|M.gilvum_PYR-GCK QAVQALAALLSTPVDEPELAVRQGKLLASRLLP-----WSRSGHLTVPRG
Mvan_1003|M.vanbaalenii_PYR-1 DAGPALARLLGAPGDEPELALRQGRLLVPRLLP-----WSRSGQLAIPRG
MAB_2212|M.abscessus_ATCC_1997 SAEEVTAEIGAMN-RAEEVAVRQGLRWTQRMRRSLPELVAPWEEPFEPTD
: . * * * . . *:
MLBr_00139|M.leprae_Br4923 DGLRVHVRKPGD--LQSLELVASDRVPPGPGQLEVAVSMSSINFADVLIA
MUL_2010|M.ulcerans_Agy99 DNMRLQIRTPGD--LQTLELAACDRVPPGPGQIEVAVTMSSINFADVLIA
MMAR_2344|M.marinum_M EGMRLQIRTPGD--LQTMEFVAFDRVAPGPGQIEVAVSTSSINFADVLVS
Mb3855c|M.bovis_AF2122/97 SGMRLQIRTPGD--MQTIELAAFHRVPPGPGQIEVAVRASSVNFADVLIA
Rv3825c|M.tuberculosis_H37Rv SGMRLQIRTPGD--MQTIELAAFHRVPPGPGQIEVAVRASSVNFADVLIA
MAV_2370|M.avium_104 DGMRLQIRTPGD--LESLELVACDRIPPGPGQIEVAVSASSINFADVLVA
MSMEG_4727|M.smegmatis_MC2_155 EGMRLVVRNPGD--LESMELVTFERGTPGPGQIEVAVKASSINFADVLVA
TH_4621|M.thermoresistible__bu DGMRLEIRTPGD--LETMELAAFDRVPPGPGQIEVAVTASSINFADVLIA
Mflv_0405|M.gilvum_PYR-GCK GDYVLAPTERGA--IDNLRLTDSEVPPPAEGYVQVRVEAAGLNFRDVLNV
Mvan_1003|M.vanbaalenii_PYR-1 TDYVLAPTERGV--LDNLRVSETEVTAPPEGHVQVRVEAAGLNFRDVLNA
MAB_2212|M.abscessus_ATCC_1997 PEVAYEVQIPDTRTLKDIKLRACDRIEPGPRQVEVRVETVGLNYKDPLKV
. :. :.. . * ::* * .:*: * *
MLBr_00139|M.leprae_Br4923 FGRFPI----IDDRDPQLGMDFVGVVTAVGEGVTGHQIGDRVGGFSEGGC
MUL_2010|M.ulcerans_Agy99 FGRYPS----LEGRLPETGTDFVGVVTAVGEGVTDHQVGDRVGGFSKDGC
MMAR_2344|M.marinum_M FGRYNS----PDGQMPQLGTDFAGVVTAVGPDVTDHQVGDRVGGMSPHGC
Mb3855c|M.bovis_AF2122/97 FGRYPS----FEGHLPQLGTDFAGVVTAVGPGVTDHKVGDHVGGMSPNGC
Rv3825c|M.tuberculosis_H37Rv FGRYPS----FEGHLPQLGTDFAGVVTAVGPGVTDHKVGDHVGGMSPNGC
MAV_2370|M.avium_104 FGRYPA----FEGRLPELGTDFAGVVTAVGPDVTDHKVGDHVGGLSANGC
MSMEG_4727|M.smegmatis_MC2_155 FGRCPS----FDGRLPELGSEFGGVVTAVGPGVTTHRVGDRVGGVSANGC
TH_4621|M.thermoresistible__bu FGRYPT----FDGRRPQLGTDFAGVVTAVGPDVTSHRVGDRVGGLSPNGC
Mflv_0405|M.gilvum_PYR-GCK LGLYP-------GDPGPIGGDFAGTVTQLGEGVTGLDVGQRVYGSMQG-A
Mvan_1003|M.vanbaalenii_PYR-1 LGLYP-------GDPGPIGGELAGVVTAPGPDVDGFDVGQRVFGFAVG-A
MAB_2212|M.abscessus_ATCC_1997 LGILTERELGKTYFKLEPGMEGFGVITRVGSQVTEVRVGESIA-VAERGL
:* * : *.:* * * :*: :
MLBr_00139|M.leprae_Br4923 WRTFLTCDAN--------LAVTLPSGLTDEQAITAATAHATAWYGLNDLA
MUL_2010|M.ulcerans_Agy99 WRSYLTCDAN--------LAVTLPAGLSDEHAAASSTAHATAWYGLNDLA
MMAR_2344|M.marinum_M WATFVTCDGA--------LATPIPAGLTDAQAAAVTTAHATAWYGLHDLG
Mb3855c|M.bovis_AF2122/97 WGTFVTCDAR--------LAATLPPGLGDAQAAAVTTAHATAWYGLHELA
Rv3825c|M.tuberculosis_H37Rv WGTFVTCDAR--------LAATLPPGLGDAQAAAVTTAHATAWYGLHELA
MAV_2370|M.avium_104 WGTFLTCDAR--------LAVTLPPGLADDQAAAVTTAHATAYYGLHELA
MSMEG_4727|M.smegmatis_MC2_155 WSNFVTCEAD--------LATKLPEGISEHEAAAVGLAYGTVWLGLTELA
TH_4621|M.thermoresistible__bu WSTFVTCDAD--------LAVPLPDGLTEGQAAAVSTAHATAWYGLHDLA
Mflv_0405|M.gilvum_PYR-GCK FASRFNVPGQ--------FLAPIPDGVSAVEAATIPAAALTVRL-SFDWA
Mvan_1003|M.vanbaalenii_PYR-1 FASRVNVPVQ--------FLAPVPEGISAVAAATTPAAVLTAGL-AFDWA
MAB_2212|M.abscessus_ATCC_1997 LRRYLTFDLDGGAAWEPIADVHLQRDEFDPLAVGSGVPFFTAGYAFYKLA
.. . : . * . *. . .
MLBr_00139|M.leprae_Br4923 GIKVGDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGI
MUL_2010|M.ulcerans_Agy99 GIKAGDRVLIHSATGGVGQAAIAIARAAGAQIFATAGNAERRQLVNDMGI
MMAR_2344|M.marinum_M RIRAGDKVLIHSGTGGVGQAAIAIARAAGAEIYATAGSPKRRQVLRDMGI
Mb3855c|M.bovis_AF2122/97 RIRAGDTVLIHSGTGGVGQAAIAIARAAGAEIFATAGTPQRRELLRNMGI
Rv3825c|M.tuberculosis_H37Rv RIRAGDTVLIHSGTGGVGQAAIAIARAAGAEIFATAGTPQRRELLRNMGI
MAV_2370|M.avium_104 RIGAGDRVLIHSATGGVGQAAIAIARAAGAEIFATAGSEQRRQLLRDMGI
MSMEG_4727|M.smegmatis_MC2_155 RMSAGDKILIHSATGGVGQAAIAVARAAGAEIYATAGSEKRRQLLRDWGI
TH_4621|M.thermoresistible__bu RLGAGEKVLIHSATGGVGLAAIAIARSVGAQIYATAGSPARRDLLRDMGI
Mflv_0405|M.gilvum_PYR-GCK QVKSGDKVLIHAASGGVGLAAVQMAQQCGAEVYATAST-FKRATLRKLGV
Mvan_1003|M.vanbaalenii_PYR-1 ALRAGDRVLIHAASGGVGLAAVQLARQRGATVFATASG-YKRPMLRAMGV
MAB_2212|M.abscessus_ATCC_1997 DVRPGETVLIHGAAGGMGMAAVQVAANMGAVVYATAGSEERRRAALDLGA
: *: :***..:**:* **: :* ** ::***. :* *
MLBr_00139|M.leprae_Br4923 EHVYDSRSVEFAEQIRRDTDGYGVDIVLNSLTGAAQRAG-LELLTFGGRF
MUL_2010|M.ulcerans_Agy99 EHVYDSRSIEFADQIRRDTNGYGVDIVLNSLTGAAQRAG-LELLAFGGRF
MMAR_2344|M.marinum_M EHVYDSRSIEFAEAIRADTDGYGVDIVLNSLTGAAQRAG-LELLAWGGRF
Mb3855c|M.bovis_AF2122/97 EHVYDSRSIEFAEQIRRDTNGRGVDVVLNSVTGAAQLAG-LKLLAFRGRF
Rv3825c|M.tuberculosis_H37Rv EHVYDSRSIEFAEQIRRDTNGRGVDVVLNSVTGAAQLAG-LKLLAFRGRF
MAV_2370|M.avium_104 EHVYDSRTVEFADLIRHDTDGYGVDIVLNSVTGAAQRAG-IELLAFGGRF
MSMEG_4727|M.smegmatis_MC2_155 EHVYDSRTTAFADQIRTDTDGYGVDIVLNSVTGPAQRAG-LELLAFGGRF
TH_4621|M.thermoresistible__bu EHVYDSRSTAFADEIRRDTDGYGVDVVLNSLPGAAQRAG-LELLSFGGRF
Mflv_0405|M.gilvum_PYR-GCK KHVYDSRTTDFAEQILADTDGAGVDVVLNSLTSEGFIEATLRATAQHGRF
Mvan_1003|M.vanbaalenii_PYR-1 DHVYDSRTTDFADQILADTDGAGVDVVLNSLTNDGFVAATVRATARNGRF
MAB_2212|M.abscessus_ATCC_1997 TAAFDSRSVGFVDDILQITEGRGVDVIYNSLPGEMIAQN-FAVAGEFCRI
.:***: *.: * *:* ***:: **:.. . *:
MLBr_00139|M.leprae_Br4923 VEIGKADVYGNTRLGLFPFRRGLTFYYLDLALMSVTQPDRVRELLATVFN
MUL_2010|M.ulcerans_Agy99 VEIGKADVYGNTRMGLYPFRRGLTFYYVDLGLMSVIQPERVRELLSTVYN
MMAR_2344|M.marinum_M VEIGKRDIYGDTKMGLFPFRRNLSFYGVDLGMLSITHPRLIRELLTTVYQ
Mb3855c|M.bovis_AF2122/97 VEIGKRDIYGDTKLGLFPFRRNLSFYAVDLGLLSATHPEELRDLLGTVYR
Rv3825c|M.tuberculosis_H37Rv VEIGKRDIYGDTKLGLFPFRRNLSFYAVDLGLLSATHPEELRDLLGTVYR
MAV_2370|M.avium_104 VEIGKRDIYGDTRLGLLPFRRNLTFYALDLALMSFSHPDRLRGLLRTVYR
MSMEG_4727|M.smegmatis_MC2_155 VEIGKRDIYADTRLGLFPFRRNLSFYAVDLALMTVTHPQKIRDLLATVYR
TH_4621|M.thermoresistible__bu IEIGKRDIYGDTRLGLFPFRRNLAFHGVDLGLMADSHPHKIRELLETVYR
Mflv_0405|M.gilvum_PYR-GCK AEIAKRDIWTVE--QMAAARPDLAYEIVALDTVMFTEPDRIRDLLTEVSA
Mvan_1003|M.vanbaalenii_PYR-1 AEIAKRDIWSPE--QMAAARPDIDYEVLALDAVMQQDPDRIQLLLADLAD
MAB_2212|M.abscessus_ATCC_1997 IEIGKADIYFGGATDLKPFSGNLSFHSIDMDRMLRLRPEIFRELRRECTE
**.* *:: : . .: : : : : * .: *
MLBr_00139|M.leprae_Br4923 LTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKLVLDIPRTGSRSVAV
MUL_2010|M.ulcerans_Agy99 LTAEGVLSAPECTHYPLAEAAEAIRTMSNAAHTGKLLLDMPRSGRRGVVV
MMAR_2344|M.marinum_M HTAEGVLPMPQDTHYPLAEAATAIRVMGAADHTGKLLLDIPRSGRSAVVL
Mb3855c|M.bovis_AF2122/97 LTAAGELPMPQSTHYPLVEAATAIRVMGNAEHTGKLVLHIPQTGKSLVTL
Rv3825c|M.tuberculosis_H37Rv LTAAGELPMPQSTHYPLVEAATAIRVMGNAEHTGKLVLHIPQTGKSLVTL
MAV_2370|M.avium_104 LTADGALPMPESTHYPLADAASAIRVMSAAQHTGKLVLDVPHAGRSRVVV
MSMEG_4727|M.smegmatis_MC2_155 LIADGTLPLPEITHYPLEEAATAIRIMGGAQHTGKLVIDIPDTGQSQVVV
TH_4621|M.thermoresistible__bu LTADGVLPMPQSTHYPLAEAATAIRVMSAAEHVGKLVLDVPHTGRADVVV
Mflv_0405|M.gilvum_PYR-GCK GLRDGAWTPLPAEVYPLTEARAAFRRMQQARHIGKIVVQIPNPLQP----
Mvan_1003|M.vanbaalenii_PYR-1 SLARGETAPLPFEAYPLAEATTAFRRMQQARHTGKIILQMPKPLQP----
MAB_2212|M.abscessus_ATCC_1997 MLTAGKLTPLPYTRFPIEEVVGAFEAVFRAEHMGRIVLDLRDQTPTLLPR
* . :*: :. *:. : * * *::::.:
MLBr_00139|M.leprae_Br4923 PPEQAPVYRRDGSYIITGGLGGLGLFFASKLAEAG----CGRIVLTARSQ
MUL_2010|M.ulcerans_Agy99 PPEQVEVFRGDGSYIITGGLGGLGLFFASKMAAAG----CGRIVLTARSQ
MMAR_2344|M.marinum_M PPEQVPVLRADGSYIITGGLGGLGLFLAEKMATAG----AGRIVLSSRSA
Mb3855c|M.bovis_AF2122/97 PPEQAQVFRPDGSYIITGGLGGLGLFLAEKMAAAG----CGRIVLNSRTQ
Rv3825c|M.tuberculosis_H37Rv PPEQAQVFRPDGSYIITGGLGGLGLFLAEKMAAAG----CGRIVLNSRTQ
MAV_2370|M.avium_104 PPAQVRAFRSDGAYIVTGGLGGLGLFLAEKMASPGSRAGCGRIVLCSRAL
MSMEG_4727|M.smegmatis_MC2_155 PPEQVPVFRGDGAYVITGGLGGLGLFLAERMAAAG----CGRIVVNSRSA
TH_4621|M.thermoresistible__bu PPEQASPFRSDGAYIVTGGMGGLGLYLAGEMAAAG----AGCIVLNGRSA
Mflv_0405|M.gilvum_PYR-GCK --------QPDRSYLITGGLGAIGLHTAGYLAQLG----AGDIVLTSRRA
Mvan_1003|M.vanbaalenii_PYR-1 --------HGDRSYLITGGLGALGLHAAAYLAQLG----AGDIVLTGRRM
MAB_2212|M.abscessus_ATCC_1997 KPEPAP-VRPGHSYLITGGFGGFGLATARSLARAG----ATHLILASRSG
: . :*::***:*.:** * :* * . ::: .*
MLBr_00139|M.leprae_Br4923 PNPKARQTIERLCAAG-ADIVVECGNIAEPYTADRLVNAATATGLPLRGV
MUL_2010|M.ulcerans_Agy99 PNPKSRQAIERLRANG-ADIVVECGNIAEPETADRLVSAATATGLPLRGV
MMAR_2344|M.marinum_M PSQKALETIELIRSIG-SDVVVECGDIAQPATAARLVANATATNLPLRGV
Mb3855c|M.bovis_AF2122/97 PTQKMRETIEAIAAMG-SEVVVECGDIAQPGTAERLVATAVATGLPVRGV
Rv3825c|M.tuberculosis_H37Rv PTQKMRETIEAIAAMG-SEVVVECGDIAQPGTAERLVATAVATGLPVRGV
MAV_2370|M.avium_104 PNPKALATLERIRQMG-ADIVVERGDIAEAGTAQRLLDVATATGLPVRGV
MSMEG_4727|M.smegmatis_MC2_155 PSTRSSEIIELIRATG-ADIVVECGDIAEPDTALRLVAAATQTGLPLRGV
TH_4621|M.thermoresistible__bu PSGEALRTIEQLRAAG-TEVIVECG----XXXRGQPVEVAVPT------E
Mflv_0405|M.gilvum_PYR-GCK PDAAAQQAIADIADRTKARLHVFTADVGVEADVAALLERIRAELPPLAGV
Mvan_1003|M.vanbaalenii_PYR-1 PDAATERAISEIAERYHCRIHTFAADVGDESAVRDLLERIRTELPPLAGV
MAB_2212|M.abscessus_ATCC_1997 AATEVARAQIEALRAADVDVWEEQVDISDYDQVADLIAKVEASGHPLRGV
. : :
MLBr_00139|M.leprae_Br4923 LHSAAVVEDATLTNITDELIDRDWSPKVYGSWNLHCATIG-----QPLDW
MUL_2010|M.ulcerans_Agy99 LHAAAVVEDATLSNITDELIDRDWSPKVYGSWNLHRASTG-----QPLDW
MMAR_2344|M.marinum_M LHAAAVVEDATLANITDELLDRDWAPKVYGAWHLHQATTD-----QPLDW
Mb3855c|M.bovis_AF2122/97 LHAAAVVEDATLANITDELLARDWAPKVHGAWELHEATSG-----QPLDW
Rv3825c|M.tuberculosis_H37Rv LHAAAVVEDATLANITDELLARDWAPKVHGAWELHEATSG-----QPLDW
MAV_2370|M.avium_104 LHLAAVIEDATLANITDELIERDWAAKVYGAWNLHCALQESG-AEQSLDW
MSMEG_4727|M.smegmatis_MC2_155 LHAAAVVEDATLANITDELVEHDWAPKVYGAWNLHQAVQSGGPATSELDW
TH_4621|M.thermoresistible__bu LRHADEHPDRRGAQLCDEFARGEQG----AQRNQHRTDAG-------EGQ
Mflv_0405|M.gilvum_PYR-GCK AHLAGVLDDALLSQQSVERFRTALAPKAFGAVHLDRLTRV-----DDLDF
Mvan_1003|M.vanbaalenii_PYR-1 AHLAGVLDDALLPQQSPERFRTTLAPKAFGAWHLHRLTRD-----TELEF
MAB_2212|M.abscessus_ATCC_1997 FHAAAVAHDEVIADISAESLRKVFRPKVQGALNLDKVTREHD---VPLDH
: * * .: * . . .
MLBr_00139|M.leprae_Br4923 FCLFSSGAALLGSPGQGAYAAANSWVDLFAHWRRAQGLPVSAIAWGAWGE
MUL_2010|M.ulcerans_Agy99 FCLFSSGAALMGSPGQGAYAAANSWVDAFAHWRRAQGLPVCAIGWGAWGE
MMAR_2344|M.marinum_M FCSFSSAAAMLGSPGQGAYAAANSWLDAFTHWRHNQNQPATAIAWGPWAE
Mb3855c|M.bovis_AF2122/97 FCLFSSAAALTGSPGQSAYSAANSWLDAFAHWRQAQGLPATAIAWGAWSD
Rv3825c|M.tuberculosis_H37Rv FCLFSSAAALTGSPGQSAYSAANSWLDAFAHWRQAQGLPATAIAWGAWSD
MAV_2370|M.avium_104 FCSFSSAAALVGSPGQGAYAAANSWLDAFTRWRRARGLKATAIAWGAWAQ
MSMEG_4727|M.smegmatis_MC2_155 FCAFSSAAALVGSPGQGAYAAANSWLDAFMQWRRAQGLPATSIAWGAWGE
TH_4621|M.thermoresistible__bu RDAHPPGAVGHDQPDPGALSDTG--LDERGGQFPGVGVQIPVADPGVGID
Mflv_0405|M.gilvum_PYR-GCK FLVSSSVSSLFGSPGQSNYATANAFLDGLVAQRRAQGLPATGVNFGPWAR
Mvan_1003|M.vanbaalenii_PYR-1 FIVYSSGSSVLGSPGQANYATANAVLDGLVAHRKARGLPATGVNWGPWAQ
MAB_2212|M.abscessus_ATCC_1997 FVLYSSISGLIGIVPQLTYAAANSVLDGLAASRRAAGLPALSVSWGAMSG
.. : . : :. :* . *
MLBr_00139|M.leprae_Br4923 VG----------RATFLAEGGEIMITPDEGAYAFEMLVRYDRPYSGYIPI
MUL_2010|M.ulcerans_Agy99 VG----------RATFLAEGGEIMIAPDEGMYAFEQMLRHARTYTGYIPI
MMAR_2344|M.marinum_M IG----------RAIALAESSDAAIAPDEGAYAFQTLLRHNRTYTGYTPI
Mb3855c|M.bovis_AF2122/97 IGQLGWWSASPARASALEESNYTAITPDEGAYAFEALLRHNRVYTGYAPV
Rv3825c|M.tuberculosis_H37Rv IGQLGWWSASPARASALEESNYTAITPDEGAYAFEALLRHNRVYTGYAPV
MAV_2370|M.avium_104 IG----------RGAALADSADVAITPDEGAYAFEALLRHDRACTGYAPI
MSMEG_4727|M.smegmatis_MC2_155 IG----------RGTAMAE-GDNAIAPDEGAYAFEAILRHDRVYNGYAPV
TH_4621|M.thermoresistible__bu HR-----------GAVRVDSGVPAQQGVDG-----EVVRHRTLSS-----
Mflv_0405|M.gilvum_PYR-GCK GG-------MASSEAAAANISAQGLIPLEPSAALTAMAEVVANGTAQATV
Mvan_1003|M.vanbaalenii_PYR-1 GG-------MATSDAARANLGAQGLIPLEPTAALNALGEIVAHGIASAVV
MAB_2212|M.abscessus_ATCC_1997 GG-------MAESDAIVKFLDSVGLRRLNMDMGAAFMRECSRFPLSHVAI
: : .
MLBr_00139|M.leprae_Br4923 LGAPWLPDLVRRSPWAE-----MFSSAGQGSRGP-SKFRMELLALPQDEW
MUL_2010|M.ulcerans_Agy99 IGAPWLADLVRRSPWAE-----MFQSSGQNTRGP-SKFLAELKLLPQEEW
MMAR_2344|M.marinum_M LGTPWIANLARRSRFAE-----AFRYDGVQRSER-SQLRAELAELPLDEW
Mb3855c|M.bovis_AF2122/97 IGAPWLVAFAERSRFFE-----VFSSS--NGSGT-SKFRVELNELPRDEW
Rv3825c|M.tuberculosis_H37Rv IGAPWLVAFAERSRFFE-----VFSSS--NGSGT-SKFRVELNELPRDEW
MAV_2370|M.avium_104 TGTPWLTAFAQRSPFAE-----AFRANGQSATGT-SKLRAELEELPPEEW
MSMEG_4727|M.smegmatis_MC2_155 LGASWLTAFAQRSPFAE-----LFLADTQGASET-RKLRSELAALPREEW
TH_4621|M.thermoresistible__bu ----------VRSGRSS-----RWTAPGSRCGSG-RRYGGES--------
Mflv_0405|M.gilvum_PYR-GCK LKANWQRAAKVLGSSRPPILDLVLPSAVGEITGD-SELLKQLQEIPVPQR
Mvan_1003|M.vanbaalenii_PYR-1 LKANWQRAAKLLGATRPPILDHVLPSAVAAGPGD-SALLKQLQDVPEAQR
MAB_2212|M.abscessus_ATCC_1997 AGIDWGVLRTPLPSTAKSTRFAHLSAEAAAVSNEQAAFRAAVLALPEEER
MLBr_00139|M.leprae_Br4923 SGRLRRLLVEQASVILRRTIDADRS---FIEYGLDSLGMLEMRTHIESET
MUL_2010|M.ulcerans_Agy99 AGRLRRLIAEQASVILRRTVDADRP---FVEYGLDSLGMLEMRTHIETET
MMAR_2344|M.marinum_M PTRLRRLISEQVSLILRRTIDPDRP---LTDYGLDSLGNLELRTRIETET
Mb3855c|M.bovis_AF2122/97 PARLRQLVAEQVSLILRRTVDPDRP---LPEYGLDSLGALELRTRIETET
Rv3825c|M.tuberculosis_H37Rv PARLRQLVAEQVSLILRRTVDPDRP---LPEYGLDSLGALELRTRIETET
MAV_2370|M.avium_104 STRLRRLISDQVSLILRRNVDPDRP---LPEYGLDSLGGLELLTRIQTET
MSMEG_4727|M.smegmatis_MC2_155 PTHLRRLIAEQVGLLLRRTVDPDRP---LSEYGLDSLGHLELRTRIETET
TH_4621|M.thermoresistible__bu ---------------CRRTTGP-------------AAGAAARRGRTRRRR
Mflv_0405|M.gilvum_PYR-GCK AGFVTEFLQKEVQNFLRLAQPPAATSR-FLDLGTDSLMAIELRNRLHSQF
Mvan_1003|M.vanbaalenii_PYR-1 GSFVTEHLQRELQQILGLAQPPAATGR-FLELGMDSLMAVELRNRLVGQF
MAB_2212|M.abscessus_ATCC_1997 GPMVTKELAKELANVLKVDVDSIDPKGPIADLGIDSLMAVEFAARAGKQL
. : : .
MLBr_00139|M.leprae_Br4923 G--IRLTPKVIATNNTARALAQYLADTLAEEEGVAAPAAMVSPETP----
MUL_2010|M.ulcerans_Agy99 G--VRLSPKVIASHNTARALSQHLADTLAEEEAQPAAS------------
MMAR_2344|M.marinum_M G--IRISSTDIT---TVRGLADHLCKKLTPAEDAPATM------------
Mb3855c|M.bovis_AF2122/97 G--IRLAPKNVSAT--VRGLADHLYEQLAPDDAPAAALSSQ---------
Rv3825c|M.tuberculosis_H37Rv G--IRLAPKNVSAT--VRGLADHLYEQLAPDDAPAAALSSQ---------
MAV_2370|M.avium_104 G--IRVSPADIAAIGTIRGLADLLRDKLTPAGAAQAERV-----------
MSMEG_4727|M.smegmatis_MC2_155 G--VRVSAMDMT---TIRGLAQRLCEMLDTDDAVSAPS------------
TH_4621|M.thermoresistible__bu R--PRRPP----------PPPDRVRHRAGPAHGPVRR-------------
Mflv_0405|M.gilvum_PYR-GCK GGAFTINATAVFDYPTIGGLAEYLVAQLPDAETPQAAPQSESEPGPDVTE
Mvan_1003|M.vanbaalenii_PYR-1 GSGFTITATAVFDYPTIGALAEYLAAQTPESTEEGTEMKTADPDGQPATV
MAB_2212|M.abscessus_ATCC_1997 N--IQISAFQFTPDLTLEAVGARVALLIAQGVGDPDHDGI----------
. :
MLBr_00139|M.leprae_Br4923 ----------
MUL_2010|M.ulcerans_Agy99 ----------
MMAR_2344|M.marinum_M ----------
Mb3855c|M.bovis_AF2122/97 ----------
Rv3825c|M.tuberculosis_H37Rv ----------
MAV_2370|M.avium_104 ----------
MSMEG_4727|M.smegmatis_MC2_155 ----------
TH_4621|M.thermoresistible__bu ----------
Mflv_0405|M.gilvum_PYR-GCK ----------
Mvan_1003|M.vanbaalenii_PYR-1 GHADVVLQTS
MAB_2212|M.abscessus_ATCC_1997 ----------