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MSTYPDRPVAGSRIVITGATNGIGKEIARALVRRGALLTLLARDPAKASATVRELAAENGAITAPEYIQA DLADLDSVRAAAHEIATTHPRIDTLVNNAGIHSLSGRTSADGFDLMTATNHLGPFLLTNLLLEPIVAAER ARIVITASEAHRSWPRIDLERFAEARRYNAIRSEIRYGQSKLMNILFTQELSRRLDGTGVTANCFCPGMV STGLVRDSRVLTAVAGLASRTPFVRRPDQGARMGLRLVLDEDLATTTGQFFTSTPGLGQLPAVRIRSDQK AQEELWRRSGELVSL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3438 | - | - | 100% (295) | putative short-chain dehydrogenase/reductase |
| M. abscessus ATCC 19977 | MAB_0643 | - | 3e-36 | 36.93% (306) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0646c | - | 8e-36 | 35.57% (298) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0069 | - | 1e-37 | 38.87% (301) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_0151 | - | 2e-34 | 34.09% (308) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv0439c | - | 1e-37 | 37.75% (302) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_00315 | - | 4e-30 | 34.55% (301) | short chain dehydrogenase |
| M. marinum M | MMAR_0757 | - | 6e-36 | 36.39% (305) | dehydrogenase/reductase |
| M. avium 104 | MAV_4710 | - | 5e-34 | 35.88% (301) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_0876 | - | 4e-37 | 38.87% (301) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_4179 | - | 1e-34 | 35.29% (306) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_1391 | - | 7e-36 | 36.39% (305) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_0753 | - | 4e-34 | 36.25% (309) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0757|M.marinum_M MSANGKAKSHWSASDIPDQSGRVVVVTGANTGLGYHTAEALAGRGAHVVL
MUL_1391|M.ulcerans_Agy99 MSAKGKAKSHWSASDIPDQSGRVVVVTGANTGLGYHTAEALADRGAHVVL
Rv0439c|M.tuberculosis_H37Rv MTANDNKTRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVL
MAV_4710|M.avium_104 MAPHDKRHRDWSEADVGDQSGRVVVITGANTGIGYETAAVLAHRGAHVVL
Mflv_0151|M.gilvum_PYR-GCK MTS------KWTAADVPDQSGRVAVVTGANTGIGYETAEVLAGKGARVVI
Mvan_0753|M.vanbaalenii_PYR-1 MSS------KWTAADVPDQSGRVAVVTGANSGIGYEAAAVLAGRGARVVV
TH_4179|M.thermoresistible__bu MTG------KWTARDVPDQTGRTAVITGANTGLGFETAKVLAEKGAHVVL
Mb0069|M.bovis_AF2122/97 MTK-------WTAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVL
MSMEG_0876|M.smegmatis_MC2_155 MTK-------WTTARIPDQTGRVAIVTGANTGLGLETAKALAAKGAHVVL
MLBr_00315|M.leprae_Br4923 MAK-------WTTADIPDQTGRVAVITGANTGLGYQTALALAEHGAHVVL
MAB_3438|M.abscessus_ATCC_1997 ----------MSTYPDRPVAGSRIVITGATNGIGKEIARALVRRGALLTL
: :* ::***..*:* . * .:. :** :.:
MMAR_0757|M.marinum_M AVRNPEKGNAAVAQIVAAK-PQADVTLQALDLSSLDSVRSAADALRSAYP
MUL_1391|M.ulcerans_Agy99 AVRNPEKGNAAVAQIVAAK-PQADVTLQALDLSSLDSVRSAADALRSAYP
Rv0439c|M.tuberculosis_H37Rv AVRNLEKGNAARARIMAAR-PGAHVTLQQLDLCSLDSVRAAADALRTAYP
MAV_4710|M.avium_104 AVRDLEKGNAALSRIVAAS-PNADVTLQQLDLASLASVRSAAEALRAAYP
Mflv_0151|M.gilvum_PYR-GCK AVRDAGKGQKALDAITRKH-PGAAVSLQELDLSSLGSVRRATDALRSAHP
Mvan_0753|M.vanbaalenii_PYR-1 AVRNLDKGRQAVSRIRQLH-PGADVMLQELDLSSLASVRAAADDLRAAHP
TH_4179|M.thermoresistible__bu AVRDPDKGRRAADRITAAA-PHADVTVRQLDLTSLDNIRRAADDLRAGYP
Mb0069|M.bovis_AF2122/97 AVRNLDKGKQAAARITEAT-PGAEVELQELDLTSLASVRAAAAQLKSDHQ
MSMEG_0876|M.smegmatis_MC2_155 AVRNLDKGKAAVDWIARSA-PTADLELQQLDLGSLASVRAAADDLKGKFD
MLBr_00315|M.leprae_Br4923 AVRNLDKGKDAAARITATS-AQNNVALQELDLASLESVRAAAKQLRSDYD
MAB_3438|M.abscessus_ATCC_1997 LARDPAKASATVRELAAENGAITAPEYIQADLADLDSVRAAAHEIATTHP
.*: *. : : . ** .* .:* *: : .
MMAR_0757|M.marinum_M RIDLLINNAGVMWTPKQVTKDGFEMQFGTNHLGHFALTGLLLDHLLPVPG
MUL_1391|M.ulcerans_Agy99 RIDLLINNAGVMWTPKQVTKDGFEMQFGTNHLGHFALTGLLLDHLLPVPG
Rv0439c|M.tuberculosis_H37Rv RIDVLINNAGVMWTPKQVTKDGFELQFGTNHLGHFALTGLVLDHMLPVPG
MAV_4710|M.avium_104 RIDLLINNAGVMWTPKQVTEDGFELQFGTNHLGHFALTGLLLDHLLGVRD
Mflv_0151|M.gilvum_PYR-GCK RIDLLINNAGVMYPPKQVTRDGFELQFGTNHLGHFAFTGLLLDNLLDVPG
Mvan_0753|M.vanbaalenii_PYR-1 RIDLLINNAGVMYPPKQTTSDGFELQFGTNHLGHFALTGLLLDRLLPVEG
TH_4179|M.thermoresistible__bu RIDLLINNAGVMYPPRQTTRDGFELQFGTNHLGHFALTGQLLDNILPVDG
Mb0069|M.bovis_AF2122/97 RIDLLINNAGVMYTPRQTTADGFEMQFGTNHLGHFALTGLLIDRLLPVAG
MSMEG_0876|M.smegmatis_MC2_155 RIDLLVNNAGVMWPPRQTTADGFELQFGTNHLGHFALTGLLLDRMLTVPG
MLBr_00315|M.leprae_Br4923 HIDLLINNAGVMWTPKSTTKDGFELQFGTNHLGHFAFTGLLLDRLLPIVG
MAB_3438|M.abscessus_ATCC_1997 RIDTLVNNAGIHSLSGRTSADGFDLMTATNHLGPFLLTNLLLEPIVAAER
:** *:****: . .: ***:: .***** * :*. ::: ::
MMAR_0757|M.marinum_M SRVITVSSLGHRIRAAIHFDDLQWERSYNRVA---AYGQSKLANLLFTYE
MUL_1391|M.ulcerans_Agy99 SRVITVSSLGHRIRAAIHFDDLQWERSYNRVA---AYGQSKLANLLFTYE
Rv0439c|M.tuberculosis_H37Rv SRVVTVSSQGHRIHAAIHFDDLQWERRYNRVA---AYGQAKLANLLFTYE
MAV_4710|M.avium_104 SRVVTVSSLGHRLRAAIHFDDLHWERRYDRVA---AYGQSKLANLLFTYE
Mflv_0151|M.gilvum_PYR-GCK SRVVTVASLAHKNLADIHFDDLQWERKYNRVA---AYGQSKLANLMFTYE
Mvan_0753|M.vanbaalenii_PYR-1 SRVVSVASIAHNIQADIHFDDLQWERSYNRVA---AYGQSKLANLMFTYT
TH_4179|M.thermoresistible__bu SRVVTVASIAHRNMADIHFDDLQWERGYHRVA---AYGQSKLANLMFAYE
Mb0069|M.bovis_AF2122/97 SRVVTISSVGHRIRAAIHFDDLQWERRYRRVA---AYGQAKLANLLFTYE
MSMEG_0876|M.smegmatis_MC2_155 SRVVTVSSQGHRILAAIHFDDLQWERRYNRVA---AYGQSKLANLLFTYE
MLBr_00315|M.leprae_Br4923 SRVITVSSLSHRLFADIHFNDLQWECNYNRVA---AYGQSKLANLLFTYE
MAB_3438|M.abscessus_ATCC_1997 ARIVITASEAHRSWPRIDLERFAEARRYNAIRSEIRYGQSKLMNILFTQE
:*:: :* .*. . *.:: : * : ***:** *::*:
MMAR_0757|M.marinum_M LQRRLAADSQAATIAVAAHPGGSNTELARNLPRMLVPLANILGPALFQSA
MUL_1391|M.ulcerans_Agy99 LQRRLAADSQAATIAVAAHPGDSNTELARNLPRMLVPLANILGPALFQSA
Rv0439c|M.tuberculosis_H37Rv LQRRLG-EAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSP
MAV_4710|M.avium_104 LQRRLAAAPDAKTIAVAAHPGGSNTELARHLPGIFRPVQAVLGPVLFQSP
Mflv_0151|M.gilvum_PYR-GCK LQRRLA-ARGAPTIAVAAHPGISNTELMRHVPGTSLPGVMKLAGLVTNTP
Mvan_0753|M.vanbaalenii_PYR-1 LARRLA-AKGAPTIAVAAHPGISNTELMRHIPGSQLPGFAWLAGLVTNSP
TH_4179|M.thermoresistible__bu LQRRLS-AKNAPTISVAAHPGVSNTELTRYIPGARLPGVSLLAGLLTNSP
Mb0069|M.bovis_AF2122/97 LQRRLAPGGTT--IAVASHPGVSNTELVRNMPRPLVAVAAILAP-LMQDA
MSMEG_0876|M.smegmatis_MC2_155 LQRRLT-GHQT--TALAAHPGASNTELARHLPG---ALERLVTP-LAQDA
MLBr_00315|M.leprae_Br4923 LQRRLATRQTT--IAVAAHPGGSRTELTRTLPALIAPIFSVAELFLTQDA
MAB_3438|M.abscessus_ATCC_1997 LSRRLD---GTGVTANCFCPGMVSTGLVRDSRVLTAVAGLASRTPFVRRP
* *** : . ** * * * . . .
MMAR_0757|M.marinum_M QMGALPTLRAATDPSVAGGQYYGPDGFAEQRGHPKIVQSSAQSHDEDLQR
MUL_1391|M.ulcerans_Agy99 QMGALPTLRTATDPSAAGGQYYGPDGFAEQRGHPKIVQSSAQSHDEDLQR
Rv0439c|M.tuberculosis_H37Rv EMGALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQR
MAV_4710|M.avium_104 AMGALPTLRAATDPAVQGAQYYGPDGFLEQRGRPKLVESSAQSHDEQLQR
Mflv_0151|M.gilvum_PYR-GCK AVGALPTVRAATDPGVTGGQYYGPSGFNEMVGHPVLVTSNKKSHDVAVQQ
Mvan_0753|M.vanbaalenii_PYR-1 AVGSLATLRAATDPGVRGGQYYGPSGVRELVGHPVLVQSNRKSHDVDVQE
TH_4179|M.thermoresistible__bu AVGALATLRAATDPEVKGGQYYGPDGFQEIRGHPVLVGSSAKSRDEDIQR
Mb0069|M.bovis_AF2122/97 ELGALPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEQLQR
MSMEG_0876|M.smegmatis_MC2_155 ALGALPTLRAATDPGALGGQYFGPDGIGETRGYPKVVASSAQSHDADLQR
MLBr_00315|M.leprae_Br4923 ATGALPTLRAATDAAVLGGQYFGPDGFAEIRGHPKVVASNGKSHDVDRQL
MAB_3438|M.abscessus_ATCC_1997 DQGARMGLRLVLDEDLATT---TGQFFTSTPGLGQLPAVRIRS-DQKAQE
*: :* . * . . . * : :* * *
MMAR_0757|M.marinum_M RLWTVSEELTGVSFPV-------
MUL_1391|M.ulcerans_Agy99 RLWTVSEELTGVSFPV-------
Rv0439c|M.tuberculosis_H37Rv RLWTVSEELTGVSFGV-------
MAV_4710|M.avium_104 RLWAVSEELTGVHFPV-------
Mflv_0151|M.gilvum_PYR-GCK RLWTVSEELTGVKYGV-------
Mvan_0753|M.vanbaalenii_PYR-1 RLWTVSEELTGVSYDL-------
TH_4179|M.thermoresistible__bu RLWTVSEELTGVTFPV-------
Mb0069|M.bovis_AF2122/97 RLWAVSEELTGVVYPVG------
MSMEG_0876|M.smegmatis_MC2_155 RLWAVSEELTGVTFPVGEALQQA
MLBr_00315|M.leprae_Br4923 RLWAVSEELTGVVYPVG------
MAB_3438|M.abscessus_ATCC_1997 ELWRRSGELVSL-----------
.** * **..: