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AKWTTADIPDQTGRVAVITGANTGLGYQTALALAEHGAHVVLAVRNLDKGKDAAARITATSAQNNVALQE LDLASLESVRAAAKQLRSDYDHIDLLINNAGVMWTPKSTTKDGFELQFGTNHLGHFAFTGLLLDRLLPIV GSRVITVSSLSHRLFADIHFNDLQWECNYNRVAAYGQSKLANLLFTYELQRRLATRQTTIAVAAHPGGSR TELTRTLPALIAPIFSVAELFLTQDAATGALPTLRAATDAAVLGGQYFGPDGFAEIRGHPKVVASNGKSH DVDRQLRLWAVSEELTGVVYPVG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_00315 | - | - | 100% (304) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_00862 | ephD | 2e-09 | 28.57% (182) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01094 | - | 6e-09 | 27.01% (211) | short chain alcohol dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0069 | - | 1e-125 | 74.18% (306) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_0151 | - | 1e-106 | 66.01% (303) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv0068 | - | 1e-125 | 73.86% (306) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0646c | - | 1e-118 | 70.10% (301) | short chain dehydrogenase |
| M. marinum M | MMAR_0757 | - | 1e-119 | 71.19% (302) | dehydrogenase/reductase |
| M. avium 104 | MAV_4710 | - | 1e-112 | 68.87% (302) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_0876 | - | 1e-117 | 70.07% (304) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_4179 | - | 1e-111 | 66.23% (302) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_1391 | - | 1e-118 | 70.20% (302) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_0762 | - | 1e-109 | 66.01% (303) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0069|M.bovis_AF2122/97 -------MTKWTAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVL
Rv0068|M.tuberculosis_H37Rv -------MTKWTAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVL
MSMEG_0876|M.smegmatis_MC2_155 -------MTKWTTARIPDQTGRVAIVTGANTGLGLETAKALAAKGAHVVL
MAB_0646c|M.abscessus_ATCC_199 ---MSRSTTKWSTTDIPDQTGRIAIVTGANTGLGLETAKALAAHGAHVVL
MLBr_00315|M.leprae_Br4923 -------MAKWTTADIPDQTGRVAVITGANTGLGYQTALALAEHGAHVVL
Mvan_0762|M.vanbaalenii_PYR-1 -------MTDWTTADIPDQTGRTAVITGANTGLGFETAKALAAGGARVVL
MMAR_0757|M.marinum_M MSANGKAKSHWSASDIPDQSGRVVVVTGANTGLGYHTAEALAGRGAHVVL
MUL_1391|M.ulcerans_Agy99 MSAKGKAKSHWSASDIPDQSGRVVVVTGANTGLGYHTAEALADRGAHVVL
MAV_4710|M.avium_104 MAPHDKRHRDWSEADVGDQSGRVVVITGANTGIGYETAAVLAHRGAHVVL
Mflv_0151|M.gilvum_PYR-GCK ------MTSKWTAADVPDQSGRVAVVTGANTGIGYETAEVLAGKGARVVI
TH_4179|M.thermoresistible__bu ------MTGKWTARDVPDQTGRTAVITGANTGLGFETAKVLAEKGAHVVL
.*: : **:** .::******:* .** .** **:**:
Mb0069|M.bovis_AF2122/97 AVRNLDKGKQAAARITEATPGAEVELQELDLTSLASVRAAAAQLKSDHQR
Rv0068|M.tuberculosis_H37Rv AVRNLDKGKQAAARITEATPGAEVELQELDLTSLASVRAAAAQLKSDHQR
MSMEG_0876|M.smegmatis_MC2_155 AVRNLDKGKAAVDWIARSAPTADLELQQLDLGSLASVRAAADDLKGKFDR
MAB_0646c|M.abscessus_ATCC_199 AVRNAEKGKAAAEAITAAHSNADVTLQSLDLSSLESVRRASDELKGRYDK
MLBr_00315|M.leprae_Br4923 AVRNLDKGKDAAARITATSAQNNVALQELDLASLESVRAAAKQLRSDYDH
Mvan_0762|M.vanbaalenii_PYR-1 AVRDTEKGAQAAAKMAG-----DVDVQQLDLTSLASIRSAADALKSRFDH
MMAR_0757|M.marinum_M AVRNPEKGNAAVAQIVAAKPQADVTLQALDLSSLDSVRSAADALRSAYPR
MUL_1391|M.ulcerans_Agy99 AVRNPEKGNAAVAQIVAAKPQADVTLQALDLSSLDSVRSAADALRSAYPR
MAV_4710|M.avium_104 AVRDLEKGNAALSRIVAASPNADVTLQQLDLASLASVRSAAEALRAAYPR
Mflv_0151|M.gilvum_PYR-GCK AVRDAGKGQKALDAITRKHPGAAVSLQELDLSSLGSVRRATDALRSAHPR
TH_4179|M.thermoresistible__bu AVRDPDKGRRAADRITAAAPHADVTVRQLDLTSLDNIRRAADDLRAGYPR
***: ** * :. : :: *** ** .:* *: *:. . :
Mb0069|M.bovis_AF2122/97 IDLLINNAGVMYTPRQTTADGFEMQFGTNHLGHFALTGLLIDRLLPVAGS
Rv0068|M.tuberculosis_H37Rv IDLLINNAGVMYTPRQTTADGFEMQFGTNHLGHFALTGLLIDRLLPVAGS
MSMEG_0876|M.smegmatis_MC2_155 IDLLVNNAGVMWPPRQTTADGFELQFGTNHLGHFALTGLLLDRMLTVPGS
MAB_0646c|M.abscessus_ATCC_199 IDLLINNAGVMWTEKSSTADGFELQFGTNHLGHYALTGLLLERLLPVEGS
MLBr_00315|M.leprae_Br4923 IDLLINNAGVMWTPKSTTKDGFELQFGTNHLGHFAFTGLLLDRLLPIVGS
Mvan_0762|M.vanbaalenii_PYR-1 IDLLINNAGVMTTPKGTTADGFELQFGTNHLGHFAFTGLLLDKLLDVDGA
MMAR_0757|M.marinum_M IDLLINNAGVMWTPKQVTKDGFEMQFGTNHLGHFALTGLLLDHLLPVPGS
MUL_1391|M.ulcerans_Agy99 IDLLINNAGVMWTPKQVTKDGFEMQFGTNHLGHFALTGLLLDHLLPVPGS
MAV_4710|M.avium_104 IDLLINNAGVMWTPKQVTEDGFELQFGTNHLGHFALTGLLLDHLLGVRDS
Mflv_0151|M.gilvum_PYR-GCK IDLLINNAGVMYPPKQVTRDGFELQFGTNHLGHFAFTGLLLDNLLDVPGS
TH_4179|M.thermoresistible__bu IDLLINNAGVMYPPRQTTRDGFELQFGTNHLGHFALTGQLLDNILPVDGS
****:****** . : * ****:*********:*:** *::.:* : .:
Mb0069|M.bovis_AF2122/97 RVVTISSVGHRIRAAIHFDDLQWERRYRRVAAYGQAKLANLLFTYELQRR
Rv0068|M.tuberculosis_H37Rv RVVTISSVGHRIRAAIHFDDLQWERRYRRVAAYGQAKLANLLFTYELQRR
MSMEG_0876|M.smegmatis_MC2_155 RVVTVSSQGHRILAAIHFDDLQWERRYNRVAAYGQSKLANLLFTYELQRR
MAB_0646c|M.abscessus_ATCC_199 RVVTVSSIGHRIRADIHFDDLQWERDYDRVAAYGQSKLANLLFTYELQRR
MLBr_00315|M.leprae_Br4923 RVITVSSLSHRLFADIHFNDLQWECNYNRVAAYGQSKLANLLFTYELQRR
Mvan_0762|M.vanbaalenii_PYR-1 RIVTVSSNGHKMGGAIHWDDLQWERSYSRMGAYSQSKLANLLFTYELQRR
MMAR_0757|M.marinum_M RVITVSSLGHRIRAAIHFDDLQWERSYNRVAAYGQSKLANLLFTYELQRR
MUL_1391|M.ulcerans_Agy99 RVITVSSLGHRIRAAIHFDDLQWERSYNRVAAYGQSKLANLLFTYELQRR
MAV_4710|M.avium_104 RVVTVSSLGHRLRAAIHFDDLHWERRYDRVAAYGQSKLANLLFTYELQRR
Mflv_0151|M.gilvum_PYR-GCK RVVTVASLAHKNLADIHFDDLQWERKYNRVAAYGQSKLANLMFTYELQRR
TH_4179|M.thermoresistible__bu RVVTVASIAHRNMADIHFDDLQWERGYHRVAAYGQSKLANLMFAYELQRR
*::*::* .*: . **::**:** * *:.**.*:*****:*:******
Mb0069|M.bovis_AF2122/97 LAP--GGTTIAVASHPGVSNTELVRNMPRPLVAVAAILAP-LMQDAELGA
Rv0068|M.tuberculosis_H37Rv LAP--GGTTIAVASHPGVSNTEVVRNMPRPLVAVAAILAP-LMQDAELGA
MSMEG_0876|M.smegmatis_MC2_155 LT---GHQTTALAAHPGASNTELARHLPG---ALERLVTP-LAQDAALGA
MAB_0646c|M.abscessus_ATCC_199 LA---GTNTVALAAHPGGSNTELARNSPLWVRAVFDVVAPVLVQGADMGA
MLBr_00315|M.leprae_Br4923 LAT--RQTTIAVAAHPGGSRTELTRTLPALIAPIFSVAELFLTQDAATGA
Mvan_0762|M.vanbaalenii_PYR-1 LAP--RGKTIAVAAHPGTSSTELGRNLPAALQPALNRLAPLLAQSPAAGA
MMAR_0757|M.marinum_M LAADSQAATIAVAAHPGGSNTELARNLPRMLVPLANILGPALFQSAQMGA
MUL_1391|M.ulcerans_Agy99 LAADSQAATIAVAAHPGDSNTELARNLPRMLVPLANILGPALFQSAQMGA
MAV_4710|M.avium_104 LAAAPDAKTIAVAAHPGGSNTELARHLPGIFRPVQAVLGPVLFQSPAMGA
Mflv_0151|M.gilvum_PYR-GCK LAAR-GAPTIAVAAHPGISNTELMRHVPGTSLPGVMKLAGLVTNTPAVGA
TH_4179|M.thermoresistible__bu LSAK-NAPTISVAAHPGVSNTELTRYIPGARLPGVSLLAGLLTNSPAVGA
*: * ::*:*** * **: * * . : : . **
Mb0069|M.bovis_AF2122/97 LPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEQLQRRLWA
Rv0068|M.tuberculosis_H37Rv LPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEQLQRRLWA
MSMEG_0876|M.smegmatis_MC2_155 LPTLRAATDPGALGGQYFGPDGIGETRGYPKVVASSAQSHDADLQRRLWA
MAB_0646c|M.abscessus_ATCC_199 LPTLRAATDPAALGGQYYGPDGFMEQRGNPKVVASSEQSYNLDLQRRLWS
MLBr_00315|M.leprae_Br4923 LPTLRAATDAAVLGGQYFGPDGFAEIRGHPKVVASNGKSHDVDRQLRLWA
Mvan_0762|M.vanbaalenii_PYR-1 LPTLRAATDPSVLGGQYYGPDGIGQQRGNPVVVASSNQSYDMALQRRLWT
MMAR_0757|M.marinum_M LPTLRAATDPSVAGGQYYGPDGFAEQRGHPKIVQSSAQSHDEDLQRRLWT
MUL_1391|M.ulcerans_Agy99 LPTLRTATDPSAAGGQYYGPDGFAEQRGHPKIVQSSAQSHDEDLQRRLWT
MAV_4710|M.avium_104 LPTLRAATDPAVQGAQYYGPDGFLEQRGRPKLVESSAQSHDEQLQRRLWA
Mflv_0151|M.gilvum_PYR-GCK LPTVRAATDPGVTGGQYYGPSGFNEMVGHPVLVTSNKKSHDVAVQQRLWT
TH_4179|M.thermoresistible__bu LATLRAATDPEVKGGQYYGPDGFQEIRGHPVLVGSSAKSRDEDIQRRLWT
*.*:*:***. . *.**:**.*: : * * :* *. :* : * ***:
Mb0069|M.bovis_AF2122/97 VSEELTGVVYPVG------
Rv0068|M.tuberculosis_H37Rv VSEELTGVVYPVG------
MSMEG_0876|M.smegmatis_MC2_155 VSEELTGVTFPVGEALQQA
MAB_0646c|M.abscessus_ATCC_199 VSEELTDVVFPVK------
MLBr_00315|M.leprae_Br4923 VSEELTGVVYPVG------
Mvan_0762|M.vanbaalenii_PYR-1 VSEELTGVTFPVPVLS---
MMAR_0757|M.marinum_M VSEELTGVSFPV-------
MUL_1391|M.ulcerans_Agy99 VSEELTGVSFPV-------
MAV_4710|M.avium_104 VSEELTGVHFPV-------
Mflv_0151|M.gilvum_PYR-GCK VSEELTGVKYGV-------
TH_4179|M.thermoresistible__bu VSEELTGVTFPV-------
******.* : *