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SAKGKAKSHWSASDIPDQSGRVVVVTGANTGLGYHTAEALADRGAHVVLAVRNPEKGNAAVAQIVAAKPQ ADVTLQALDLSSLDSVRSAADALRSAYPRIDLLINNAGVMWTPKQVTKDGFEMQFGTNHLGHFALTGLLL DHLLPVPGSRVITVSSLGHRIRAAIHFDDLQWERSYNRVAAYGQSKLANLLFTYELQRRLAADSQAATIA VAAHPGDSNTELARNLPRMLVPLANILGPALFQSAQMGALPTLRTATDPSAAGGQYYGPDGFAEQRGHPK IVQSSAQSHDEDLQRRLWTVSEELTGVSFPV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1391 | - | - | 100% (312) | short chain dehydrogenase |
| M. ulcerans Agy99 | MUL_1288 | - | 1e-64 | 46.75% (308) | short chain dehydrogenase |
| M. ulcerans Agy99 | MUL_1918 | - | 1e-27 | 32.01% (303) | dehydrogenase/reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0447c | - | 1e-146 | 80.77% (312) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_0151 | - | 1e-114 | 68.42% (304) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv0439c | - | 1e-146 | 80.77% (312) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_00315 | - | 1e-118 | 70.20% (302) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0646c | - | 1e-123 | 71.34% (307) | short chain dehydrogenase |
| M. marinum M | MMAR_0757 | - | 1e-174 | 98.40% (312) | dehydrogenase/reductase |
| M. avium 104 | MAV_4710 | - | 1e-137 | 77.88% (312) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_0876 | - | 1e-119 | 70.92% (306) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_4179 | - | 1e-119 | 68.87% (302) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_0753 | - | 1e-113 | 68.54% (302) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_1391|M.ulcerans_Agy99 MSAKGKAKSHWSASDIPDQSGRVVVVTGANTGLGYHTAEALADRGAHVVL
MMAR_0757|M.marinum_M MSANGKAKSHWSASDIPDQSGRVVVVTGANTGLGYHTAEALAGRGAHVVL
Mb0447c|M.bovis_AF2122/97 MTANDNKTRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVL
Rv0439c|M.tuberculosis_H37Rv MTANDNKTRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVL
MAV_4710|M.avium_104 MAPHDKRHRDWSEADVGDQSGRVVVITGANTGIGYETAAVLAHRGAHVVL
MAB_0646c|M.abscessus_ATCC_199 ---MSRSTTKWSTTDIPDQTGRIAIVTGANTGLGLETAKALAAHGAHVVL
MSMEG_0876|M.smegmatis_MC2_155 -------MTKWTTARIPDQTGRVAIVTGANTGLGLETAKALAAKGAHVVL
MLBr_00315|M.leprae_Br4923 -------MAKWTTADIPDQTGRVAVITGANTGLGYQTALALAEHGAHVVL
Mflv_0151|M.gilvum_PYR-GCK ------MTSKWTAADVPDQSGRVAVVTGANTGIGYETAEVLAGKGARVVI
Mvan_0753|M.vanbaalenii_PYR-1 ------MSSKWTAADVPDQSGRVAVVTGANSGIGYEAAAVLAGRGARVVV
TH_4179|M.thermoresistible__bu ------MTGKWTARDVPDQTGRTAVITGANTGLGFETAKVLAEKGAHVVL
.*: : **:** .::****:*:* .:* .:* :**:**:
MUL_1391|M.ulcerans_Agy99 AVRNPEKGNAAVAQIVAAKPQADVTLQALDLSSLDSVRSAADALRSAYPR
MMAR_0757|M.marinum_M AVRNPEKGNAAVAQIVAAKPQADVTLQALDLSSLDSVRSAADALRSAYPR
Mb0447c|M.bovis_AF2122/97 AVRNLEKGNAARARIMAARPGAHVTLQQLDLCSLDSVRAAADALRTAYPR
Rv0439c|M.tuberculosis_H37Rv AVRNLEKGNAARARIMAARPGAHVTLQQLDLCSLDSVRAAADALRTAYPR
MAV_4710|M.avium_104 AVRDLEKGNAALSRIVAASPNADVTLQQLDLASLASVRSAAEALRAAYPR
MAB_0646c|M.abscessus_ATCC_199 AVRNAEKGKAAAEAITAAHSNADVTLQSLDLSSLESVRRASDELKGRYDK
MSMEG_0876|M.smegmatis_MC2_155 AVRNLDKGKAAVDWIARSAPTADLELQQLDLGSLASVRAAADDLKGKFDR
MLBr_00315|M.leprae_Br4923 AVRNLDKGKDAAARITATSAQNNVALQELDLASLESVRAAAKQLRSDYDH
Mflv_0151|M.gilvum_PYR-GCK AVRDAGKGQKALDAITRKHPGAAVSLQELDLSSLGSVRRATDALRSAHPR
Mvan_0753|M.vanbaalenii_PYR-1 AVRNLDKGRQAVSRIRQLHPGADVMLQELDLSSLASVRAAADDLRAAHPR
TH_4179|M.thermoresistible__bu AVRDPDKGRRAADRITAAAPHADVTVRQLDLTSLDNIRRAADDLRAGYPR
***: **. * * . : :: *** ** .:* *:. *: . :
MUL_1391|M.ulcerans_Agy99 IDLLINNAGVMWTPKQVTKDGFEMQFGTNHLGHFALTGLLLDHLLPVPGS
MMAR_0757|M.marinum_M IDLLINNAGVMWTPKQVTKDGFEMQFGTNHLGHFALTGLLLDHLLPVPGS
Mb0447c|M.bovis_AF2122/97 IDVLINNAGVMWTPKQVTKDGFELQFGTNHLGHFALTGLVLDHMLPVPGS
Rv0439c|M.tuberculosis_H37Rv IDVLINNAGVMWTPKQVTKDGFELQFGTNHLGHFALTGLVLDHMLPVPGS
MAV_4710|M.avium_104 IDLLINNAGVMWTPKQVTEDGFELQFGTNHLGHFALTGLLLDHLLGVRDS
MAB_0646c|M.abscessus_ATCC_199 IDLLINNAGVMWTEKSSTADGFELQFGTNHLGHYALTGLLLERLLPVEGS
MSMEG_0876|M.smegmatis_MC2_155 IDLLVNNAGVMWPPRQTTADGFELQFGTNHLGHFALTGLLLDRMLTVPGS
MLBr_00315|M.leprae_Br4923 IDLLINNAGVMWTPKSTTKDGFELQFGTNHLGHFAFTGLLLDRLLPIVGS
Mflv_0151|M.gilvum_PYR-GCK IDLLINNAGVMYPPKQVTRDGFELQFGTNHLGHFAFTGLLLDNLLDVPGS
Mvan_0753|M.vanbaalenii_PYR-1 IDLLINNAGVMYPPKQTTSDGFELQFGTNHLGHFALTGLLLDRLLPVEGS
TH_4179|M.thermoresistible__bu IDLLINNAGVMYPPRQTTRDGFELQFGTNHLGHFALTGQLLDNILPVDGS
**:*:******:. :. * ****:*********:*:** :*:.:* : .*
MUL_1391|M.ulcerans_Agy99 RVITVSSLGHRIRAAIHFDDLQWERSYNRVAAYGQSKLANLLFTYELQRR
MMAR_0757|M.marinum_M RVITVSSLGHRIRAAIHFDDLQWERSYNRVAAYGQSKLANLLFTYELQRR
Mb0447c|M.bovis_AF2122/97 RVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLANLLFTYELQRR
Rv0439c|M.tuberculosis_H37Rv RVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLANLLFTYELQRR
MAV_4710|M.avium_104 RVVTVSSLGHRLRAAIHFDDLHWERRYDRVAAYGQSKLANLLFTYELQRR
MAB_0646c|M.abscessus_ATCC_199 RVVTVSSIGHRIRADIHFDDLQWERDYDRVAAYGQSKLANLLFTYELQRR
MSMEG_0876|M.smegmatis_MC2_155 RVVTVSSQGHRILAAIHFDDLQWERRYNRVAAYGQSKLANLLFTYELQRR
MLBr_00315|M.leprae_Br4923 RVITVSSLSHRLFADIHFNDLQWECNYNRVAAYGQSKLANLLFTYELQRR
Mflv_0151|M.gilvum_PYR-GCK RVVTVASLAHKNLADIHFDDLQWERKYNRVAAYGQSKLANLMFTYELQRR
Mvan_0753|M.vanbaalenii_PYR-1 RVVSVASIAHNIQADIHFDDLQWERSYNRVAAYGQSKLANLMFTYTLARR
TH_4179|M.thermoresistible__bu RVVTVASIAHRNMADIHFDDLQWERGYHRVAAYGQSKLANLMFAYELQRR
**::*:* .*. * ***:**:** *.*******:*****:*:* * **
MUL_1391|M.ulcerans_Agy99 LAADSQAATIAVAAHPGDSNTELARNLPRMLVPLANILGPALFQSAQMGA
MMAR_0757|M.marinum_M LAADSQAATIAVAAHPGGSNTELARNLPRMLVPLANILGPALFQSAQMGA
Mb0447c|M.bovis_AF2122/97 LG-EAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGA
Rv0439c|M.tuberculosis_H37Rv LG-EAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGA
MAV_4710|M.avium_104 LAAAPDAKTIAVAAHPGGSNTELARHLPGIFRPVQAVLGPVLFQSPAMGA
MAB_0646c|M.abscessus_ATCC_199 LAG---TNTVALAAHPGGSNTELARNSPLWVRAVFDVVAPVLVQGADMGA
MSMEG_0876|M.smegmatis_MC2_155 LTG---HQTTALAAHPGASNTELARHLP----GALERLVTPLAQDAALGA
MLBr_00315|M.leprae_Br4923 LATR--QTTIAVAAHPGGSRTELTRTLPALIAPIFSVAELFLTQDAATGA
Mflv_0151|M.gilvum_PYR-GCK LAARG-APTIAVAAHPGISNTELMRHVPGTSLPGVMKLAGLVTNTPAVGA
Mvan_0753|M.vanbaalenii_PYR-1 LAAKG-APTIAVAAHPGISNTELMRHIPGSQLPGFAWLAGLVTNSPAVGS
TH_4179|M.thermoresistible__bu LSAKN-APTISVAAHPGVSNTELTRYIPGARLPGVSLLAGLLTNSPAVGA
* * ::***** *.*** * * : : . *:
MUL_1391|M.ulcerans_Agy99 LPTLRTATDPSAAGGQYYGPDGFAEQRGHPKIVQSSAQSHDEDLQRRLWT
MMAR_0757|M.marinum_M LPTLRAATDPSVAGGQYYGPDGFAEQRGHPKIVQSSAQSHDEDLQRRLWT
Mb0447c|M.bovis_AF2122/97 LPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWT
Rv0439c|M.tuberculosis_H37Rv LPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWT
MAV_4710|M.avium_104 LPTLRAATDPAVQGAQYYGPDGFLEQRGRPKLVESSAQSHDEQLQRRLWA
MAB_0646c|M.abscessus_ATCC_199 LPTLRAATDPAALGGQYYGPDGFMEQRGNPKVVASSEQSYNLDLQRRLWS
MSMEG_0876|M.smegmatis_MC2_155 LPTLRAATDPGALGGQYFGPDGIGETRGYPKVVASSAQSHDADLQRRLWA
MLBr_00315|M.leprae_Br4923 LPTLRAATDAAVLGGQYFGPDGFAEIRGHPKVVASNGKSHDVDRQLRLWA
Mflv_0151|M.gilvum_PYR-GCK LPTVRAATDPGVTGGQYYGPSGFNEMVGHPVLVTSNKKSHDVAVQQRLWT
Mvan_0753|M.vanbaalenii_PYR-1 LATLRAATDPGVRGGQYYGPSGVRELVGHPVLVQSNRKSHDVDVQERLWT
TH_4179|M.thermoresistible__bu LATLRAATDPEVKGGQYYGPDGFQEIRGHPVLVGSSAKSRDEDIQRRLWT
*.*:*:***. . *.**:**.*. * * * :* *. :* : * ***:
MUL_1391|M.ulcerans_Agy99 VSEELTGVSFPV-------
MMAR_0757|M.marinum_M VSEELTGVSFPV-------
Mb0447c|M.bovis_AF2122/97 VSEELTGVSFGV-------
Rv0439c|M.tuberculosis_H37Rv VSEELTGVSFGV-------
MAV_4710|M.avium_104 VSEELTGVHFPV-------
MAB_0646c|M.abscessus_ATCC_199 VSEELTDVVFPVK------
MSMEG_0876|M.smegmatis_MC2_155 VSEELTGVTFPVGEALQQA
MLBr_00315|M.leprae_Br4923 VSEELTGVVYPVG------
Mflv_0151|M.gilvum_PYR-GCK VSEELTGVKYGV-------
Mvan_0753|M.vanbaalenii_PYR-1 VSEELTGVSYDL-------
TH_4179|M.thermoresistible__bu VSEELTGVTFPV-------
******.* : :