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TANDNKTRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAARPG AHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTNHLGHFALTGLVL DHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLANLLFTYELQRRLGEAGKSTIAV AAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKV VQSSAQSHDKDLQRRLWTVSEELTGVSFGV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0439c | - | - | 100% (311) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv0068 | - | e-124 | 72.85% (302) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv2263 | - | 4e-61 | 46.28% (309) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0447c | - | 1e-180 | 100.00% (311) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_0151 | - | 1e-116 | 68.75% (304) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_00315 | - | 1e-117 | 69.21% (302) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0646c | - | 1e-119 | 70.72% (304) | short chain dehydrogenase |
| M. marinum M | MMAR_0757 | - | 1e-147 | 81.41% (312) | dehydrogenase/reductase |
| M. avium 104 | MAV_4710 | - | 1e-138 | 79.17% (312) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_0876 | - | 1e-118 | 71.52% (302) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_4179 | - | 1e-117 | 68.75% (304) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_1391 | - | 1e-146 | 80.77% (312) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_0753 | - | 1e-115 | 70.00% (300) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0439c|M.tuberculosis_H37Rv MTANDNKTRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVL
Mb0447c|M.bovis_AF2122/97 MTANDNKTRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVL
MMAR_0757|M.marinum_M MSANGKAKSHWSASDIPDQSGRVVVVTGANTGLGYHTAEALAGRGAHVVL
MUL_1391|M.ulcerans_Agy99 MSAKGKAKSHWSASDIPDQSGRVVVVTGANTGLGYHTAEALADRGAHVVL
MAV_4710|M.avium_104 MAPHDKRHRDWSEADVGDQSGRVVVITGANTGIGYETAAVLAHRGAHVVL
MAB_0646c|M.abscessus_ATCC_199 ---MSRSTTKWSTTDIPDQTGRIAIVTGANTGLGLETAKALAAHGAHVVL
MSMEG_0876|M.smegmatis_MC2_155 -------MTKWTTARIPDQTGRVAIVTGANTGLGLETAKALAAKGAHVVL
MLBr_00315|M.leprae_Br4923 -------MAKWTTADIPDQTGRVAVITGANTGLGYQTALALAEHGAHVVL
Mflv_0151|M.gilvum_PYR-GCK ------MTSKWTAADVPDQSGRVAVVTGANTGIGYETAEVLAGKGARVVI
Mvan_0753|M.vanbaalenii_PYR-1 ------MSSKWTAADVPDQSGRVAVVTGANSGIGYEAAAVLAGRGARVVV
TH_4179|M.thermoresistible__bu ------MTGKWTARDVPDQTGRTAVITGANTGLGFETAKVLAEKGAHVVL
.*: : **:** .::****:*:* .:* .:* :**:**:
Rv0439c|M.tuberculosis_H37Rv AVRNLEKGNAARARIMAARPGAHVTLQQLDLCSLDSVRAAADALRTAYPR
Mb0447c|M.bovis_AF2122/97 AVRNLEKGNAARARIMAARPGAHVTLQQLDLCSLDSVRAAADALRTAYPR
MMAR_0757|M.marinum_M AVRNPEKGNAAVAQIVAAKPQADVTLQALDLSSLDSVRSAADALRSAYPR
MUL_1391|M.ulcerans_Agy99 AVRNPEKGNAAVAQIVAAKPQADVTLQALDLSSLDSVRSAADALRSAYPR
MAV_4710|M.avium_104 AVRDLEKGNAALSRIVAASPNADVTLQQLDLASLASVRSAAEALRAAYPR
MAB_0646c|M.abscessus_ATCC_199 AVRNAEKGKAAAEAITAAHSNADVTLQSLDLSSLESVRRASDELKGRYDK
MSMEG_0876|M.smegmatis_MC2_155 AVRNLDKGKAAVDWIARSAPTADLELQQLDLGSLASVRAAADDLKGKFDR
MLBr_00315|M.leprae_Br4923 AVRNLDKGKDAAARITATSAQNNVALQELDLASLESVRAAAKQLRSDYDH
Mflv_0151|M.gilvum_PYR-GCK AVRDAGKGQKALDAITRKHPGAAVSLQELDLSSLGSVRRATDALRSAHPR
Mvan_0753|M.vanbaalenii_PYR-1 AVRNLDKGRQAVSRIRQLHPGADVMLQELDLSSLASVRAAADDLRAAHPR
TH_4179|M.thermoresistible__bu AVRDPDKGRRAADRITAAAPHADVTVRQLDLTSLDNIRRAADDLRAGYPR
***: **. * * . : :: *** ** .:* *:. *: . :
Rv0439c|M.tuberculosis_H37Rv IDVLINNAGVMWTPKQVTKDGFELQFGTNHLGHFALTGLVLDHMLPVPGS
Mb0447c|M.bovis_AF2122/97 IDVLINNAGVMWTPKQVTKDGFELQFGTNHLGHFALTGLVLDHMLPVPGS
MMAR_0757|M.marinum_M IDLLINNAGVMWTPKQVTKDGFEMQFGTNHLGHFALTGLLLDHLLPVPGS
MUL_1391|M.ulcerans_Agy99 IDLLINNAGVMWTPKQVTKDGFEMQFGTNHLGHFALTGLLLDHLLPVPGS
MAV_4710|M.avium_104 IDLLINNAGVMWTPKQVTEDGFELQFGTNHLGHFALTGLLLDHLLGVRDS
MAB_0646c|M.abscessus_ATCC_199 IDLLINNAGVMWTEKSSTADGFELQFGTNHLGHYALTGLLLERLLPVEGS
MSMEG_0876|M.smegmatis_MC2_155 IDLLVNNAGVMWPPRQTTADGFELQFGTNHLGHFALTGLLLDRMLTVPGS
MLBr_00315|M.leprae_Br4923 IDLLINNAGVMWTPKSTTKDGFELQFGTNHLGHFAFTGLLLDRLLPIVGS
Mflv_0151|M.gilvum_PYR-GCK IDLLINNAGVMYPPKQVTRDGFELQFGTNHLGHFAFTGLLLDNLLDVPGS
Mvan_0753|M.vanbaalenii_PYR-1 IDLLINNAGVMYPPKQTTSDGFELQFGTNHLGHFALTGLLLDRLLPVEGS
TH_4179|M.thermoresistible__bu IDLLINNAGVMYPPRQTTRDGFELQFGTNHLGHFALTGQLLDNILPVDGS
**:*:******:. :. * ****:*********:*:** :*:.:* : .*
Rv0439c|M.tuberculosis_H37Rv RVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLANLLFTYELQRR
Mb0447c|M.bovis_AF2122/97 RVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLANLLFTYELQRR
MMAR_0757|M.marinum_M RVITVSSLGHRIRAAIHFDDLQWERSYNRVAAYGQSKLANLLFTYELQRR
MUL_1391|M.ulcerans_Agy99 RVITVSSLGHRIRAAIHFDDLQWERSYNRVAAYGQSKLANLLFTYELQRR
MAV_4710|M.avium_104 RVVTVSSLGHRLRAAIHFDDLHWERRYDRVAAYGQSKLANLLFTYELQRR
MAB_0646c|M.abscessus_ATCC_199 RVVTVSSIGHRIRADIHFDDLQWERDYDRVAAYGQSKLANLLFTYELQRR
MSMEG_0876|M.smegmatis_MC2_155 RVVTVSSQGHRILAAIHFDDLQWERRYNRVAAYGQSKLANLLFTYELQRR
MLBr_00315|M.leprae_Br4923 RVITVSSLSHRLFADIHFNDLQWECNYNRVAAYGQSKLANLLFTYELQRR
Mflv_0151|M.gilvum_PYR-GCK RVVTVASLAHKNLADIHFDDLQWERKYNRVAAYGQSKLANLMFTYELQRR
Mvan_0753|M.vanbaalenii_PYR-1 RVVSVASIAHNIQADIHFDDLQWERSYNRVAAYGQSKLANLMFTYTLARR
TH_4179|M.thermoresistible__bu RVVTVASIAHRNMADIHFDDLQWERGYHRVAAYGQSKLANLMFAYELQRR
**::*:* .*. * ***:**:** *.*******:*****:*:* * **
Rv0439c|M.tuberculosis_H37Rv LG-EAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGA
Mb0447c|M.bovis_AF2122/97 LG-EAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGA
MMAR_0757|M.marinum_M LAADSQAATIAVAAHPGGSNTELARNLPRMLVPLANILGPALFQSAQMGA
MUL_1391|M.ulcerans_Agy99 LAADSQAATIAVAAHPGDSNTELARNLPRMLVPLANILGPALFQSAQMGA
MAV_4710|M.avium_104 LAAAPDAKTIAVAAHPGGSNTELARHLPGIFRPVQAVLGPVLFQSPAMGA
MAB_0646c|M.abscessus_ATCC_199 LAG---TNTVALAAHPGGSNTELARNSPLWVRAVFDVVAPVLVQGADMGA
MSMEG_0876|M.smegmatis_MC2_155 LTG---HQTTALAAHPGASNTELARHLP----GALERLVTPLAQDAALGA
MLBr_00315|M.leprae_Br4923 LATR--QTTIAVAAHPGGSRTELTRTLPALIAPIFSVAELFLTQDAATGA
Mflv_0151|M.gilvum_PYR-GCK LAARG-APTIAVAAHPGISNTELMRHVPGTSLPGVMKLAGLVTNTPAVGA
Mvan_0753|M.vanbaalenii_PYR-1 LAAKG-APTIAVAAHPGISNTELMRHIPGSQLPGFAWLAGLVTNSPAVGS
TH_4179|M.thermoresistible__bu LSAKN-APTISVAAHPGVSNTELTRYIPGARLPGVSLLAGLLTNSPAVGA
* * ::***** *.*** * * : : . *:
Rv0439c|M.tuberculosis_H37Rv LPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWT
Mb0447c|M.bovis_AF2122/97 LPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWT
MMAR_0757|M.marinum_M LPTLRAATDPSVAGGQYYGPDGFAEQRGHPKIVQSSAQSHDEDLQRRLWT
MUL_1391|M.ulcerans_Agy99 LPTLRTATDPSAAGGQYYGPDGFAEQRGHPKIVQSSAQSHDEDLQRRLWT
MAV_4710|M.avium_104 LPTLRAATDPAVQGAQYYGPDGFLEQRGRPKLVESSAQSHDEQLQRRLWA
MAB_0646c|M.abscessus_ATCC_199 LPTLRAATDPAALGGQYYGPDGFMEQRGNPKVVASSEQSYNLDLQRRLWS
MSMEG_0876|M.smegmatis_MC2_155 LPTLRAATDPGALGGQYFGPDGIGETRGYPKVVASSAQSHDADLQRRLWA
MLBr_00315|M.leprae_Br4923 LPTLRAATDAAVLGGQYFGPDGFAEIRGHPKVVASNGKSHDVDRQLRLWA
Mflv_0151|M.gilvum_PYR-GCK LPTVRAATDPGVTGGQYYGPSGFNEMVGHPVLVTSNKKSHDVAVQQRLWT
Mvan_0753|M.vanbaalenii_PYR-1 LATLRAATDPGVRGGQYYGPSGVRELVGHPVLVQSNRKSHDVDVQERLWT
TH_4179|M.thermoresistible__bu LATLRAATDPEVKGGQYYGPDGFQEIRGHPVLVGSSAKSRDEDIQRRLWT
*.*:*:***. . *.**:**.*. * * * :* *. :* : * ***:
Rv0439c|M.tuberculosis_H37Rv VSEELTGVSFGV-------
Mb0447c|M.bovis_AF2122/97 VSEELTGVSFGV-------
MMAR_0757|M.marinum_M VSEELTGVSFPV-------
MUL_1391|M.ulcerans_Agy99 VSEELTGVSFPV-------
MAV_4710|M.avium_104 VSEELTGVHFPV-------
MAB_0646c|M.abscessus_ATCC_199 VSEELTDVVFPVK------
MSMEG_0876|M.smegmatis_MC2_155 VSEELTGVTFPVGEALQQA
MLBr_00315|M.leprae_Br4923 VSEELTGVVYPVG------
Mflv_0151|M.gilvum_PYR-GCK VSEELTGVKYGV-------
Mvan_0753|M.vanbaalenii_PYR-1 VSEELTGVSYDL-------
TH_4179|M.thermoresistible__bu VSEELTGVTFPV-------
******.* : :