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SRSTTKWSTTDIPDQTGRIAIVTGANTGLGLETAKALAAHGAHVVLAVRNAEKGKAAAEAITAAHSNADV TLQSLDLSSLESVRRASDELKGRYDKIDLLINNAGVMWTEKSSTADGFELQFGTNHLGHYALTGLLLERL LPVEGSRVVTVSSIGHRIRADIHFDDLQWERDYDRVAAYGQSKLANLLFTYELQRRLAGTNTVALAAHPG GSNTELARNSPLWVRAVFDVVAPVLVQGADMGALPTLRAATDPAALGGQYYGPDGFMEQRGNPKVVASSE QSYNLDLQRRLWSVSEELTDVVFPVK*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_0646c | - | - | 100% (307) | short chain dehydrogenase |
M. abscessus ATCC 19977 | MAB_0643 | - | e-108 | 68.09% (304) | short chain dehydrogenase |
M. abscessus ATCC 19977 | MAB_1144c | - | 5e-62 | 45.95% (309) | short-chain dehydrogenase/reductase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0069 | - | 1e-120 | 72.52% (302) | short chain dehydrogenase |
M. gilvum PYR-GCK | Mflv_0143 | - | 1e-109 | 67.22% (302) | short chain dehydrogenase |
M. tuberculosis H37Rv | Rv0068 | - | 1e-120 | 72.19% (302) | short chain dehydrogenase |
M. leprae Br4923 | MLBr_00315 | - | 1e-119 | 70.10% (301) | short chain dehydrogenase |
M. marinum M | MMAR_0757 | - | 1e-124 | 71.66% (307) | dehydrogenase/reductase |
M. avium 104 | MAV_4710 | - | 1e-117 | 70.86% (302) | short chain dehydrogenase |
M. smegmatis MC2 155 | MSMEG_0876 | - | 1e-122 | 74.42% (301) | short chain dehydrogenase |
M. thermoresistible (build 8) | TH_4179 | - | 1e-110 | 65.13% (304) | PUTATIVE short-chain dehydrogenase/reductase SDR |
M. ulcerans Agy99 | MUL_1391 | - | 1e-124 | 71.34% (307) | short chain dehydrogenase |
M. vanbaalenii PYR-1 | Mvan_0762 | - | 1e-112 | 67.88% (302) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment Mb0069|M.bovis_AF2122/97 -------MTKWT---AADIPDQTGRTAVITGANTGLGFETAAALAAHGAH Rv0068|M.tuberculosis_H37Rv -------MTKWT---AADIPDQTGRTAVITGANTGLGFETAAALAAHGAH MSMEG_0876|M.smegmatis_MC2_155 -------MTKWT---TARIPDQTGRVAIVTGANTGLGLETAKALAAKGAH MLBr_00315|M.leprae_Br4923 -------MAKWT---TADIPDQTGRVAVITGANTGLGYQTALALAEHGAH MAB_0646c|M.abscessus_ATCC_199 ---MSRSTTKWS---TTDIPDQTGRIAIVTGANTGLGLETAKALAAHGAH MMAR_0757|M.marinum_M MSANGKAKSHWS---ASDIPDQSGRVVVVTGANTGLGYHTAEALAGRGAH MUL_1391|M.ulcerans_Agy99 MSAKGKAKSHWS---ASDIPDQSGRVVVVTGANTGLGYHTAEALADRGAH MAV_4710|M.avium_104 MAPHDKRHRDWS---EADVGDQSGRVVVITGANTGIGYETAAVLAHRGAH TH_4179|M.thermoresistible__bu ------MTGKWT---ARDVPDQTGRTAVITGANTGLGFETAKVLAEKGAH Mflv_0143|M.gilvum_PYR-GCK -------MTDWTNWNVADIPDQTGRTAVITGANTGLGFETAKALAEKGAR Mvan_0762|M.vanbaalenii_PYR-1 -------MTDWT---TADIPDQTGRTAVITGANTGLGFETAKALAAGGAR .*: : **:** .::******:* .** .** **: Mb0069|M.bovis_AF2122/97 VVLAVRNLDKGKQAAARITEATPGAEVELQELDLTSLASVRAAAAQLKSD Rv0068|M.tuberculosis_H37Rv VVLAVRNLDKGKQAAARITEATPGAEVELQELDLTSLASVRAAAAQLKSD MSMEG_0876|M.smegmatis_MC2_155 VVLAVRNLDKGKAAVDWIARSAPTADLELQQLDLGSLASVRAAADDLKGK MLBr_00315|M.leprae_Br4923 VVLAVRNLDKGKDAAARITATSAQNNVALQELDLASLESVRAAAKQLRSD MAB_0646c|M.abscessus_ATCC_199 VVLAVRNAEKGKAAAEAITAAHSNADVTLQSLDLSSLESVRRASDELKGR MMAR_0757|M.marinum_M VVLAVRNPEKGNAAVAQIVAAKPQADVTLQALDLSSLDSVRSAADALRSA MUL_1391|M.ulcerans_Agy99 VVLAVRNPEKGNAAVAQIVAAKPQADVTLQALDLSSLDSVRSAADALRSA MAV_4710|M.avium_104 VVLAVRDLEKGNAALSRIVAASPNADVTLQQLDLASLASVRSAAEALRAA TH_4179|M.thermoresistible__bu VVLAVRDPDKGRRAADRITAAAPHADVTVRQLDLTSLDNIRRAADDLRAG Mflv_0143|M.gilvum_PYR-GCK VVIAVRNTDKGAQAAARIRG-----DVDVQELDLTSLSSIRTAAEALKAR Mvan_0762|M.vanbaalenii_PYR-1 VVLAVRDTEKGAQAAAKMAG-----DVDVQQLDLTSLASIRSAADALKSR **:***: :** * : :: :: *** ** .:* *: *:. Mb0069|M.bovis_AF2122/97 HQRIDLLINNAGVMYTPRQTTADGFEMQFGTNHLGHFALTGLLIDRLLPV Rv0068|M.tuberculosis_H37Rv HQRIDLLINNAGVMYTPRQTTADGFEMQFGTNHLGHFALTGLLIDRLLPV MSMEG_0876|M.smegmatis_MC2_155 FDRIDLLVNNAGVMWPPRQTTADGFELQFGTNHLGHFALTGLLLDRMLTV MLBr_00315|M.leprae_Br4923 YDHIDLLINNAGVMWTPKSTTKDGFELQFGTNHLGHFAFTGLLLDRLLPI MAB_0646c|M.abscessus_ATCC_199 YDKIDLLINNAGVMWTEKSSTADGFELQFGTNHLGHYALTGLLLERLLPV MMAR_0757|M.marinum_M YPRIDLLINNAGVMWTPKQVTKDGFEMQFGTNHLGHFALTGLLLDHLLPV MUL_1391|M.ulcerans_Agy99 YPRIDLLINNAGVMWTPKQVTKDGFEMQFGTNHLGHFALTGLLLDHLLPV MAV_4710|M.avium_104 YPRIDLLINNAGVMWTPKQVTEDGFELQFGTNHLGHFALTGLLLDHLLGV TH_4179|M.thermoresistible__bu YPRIDLLINNAGVMYPPRQTTRDGFELQFGTNHLGHFALTGQLLDNILPV Mflv_0143|M.gilvum_PYR-GCK FDKIDLLINNAGVMTTPKGTTADGFELQFGTNHLGHFALTGLLFDNILDI Mvan_0762|M.vanbaalenii_PYR-1 FDHIDLLINNAGVMTTPKGTTADGFELQFGTNHLGHFAFTGLLLDKLLDV . :****:****** . : * ****:*********:*:** *::.:* : Mb0069|M.bovis_AF2122/97 AGSRVVTISSVGHRIRAAIHFDDLQWERRYRRVAAYGQAKLANLLFTYEL Rv0068|M.tuberculosis_H37Rv AGSRVVTISSVGHRIRAAIHFDDLQWERRYRRVAAYGQAKLANLLFTYEL MSMEG_0876|M.smegmatis_MC2_155 PGSRVVTVSSQGHRILAAIHFDDLQWERRYNRVAAYGQSKLANLLFTYEL MLBr_00315|M.leprae_Br4923 VGSRVITVSSLSHRLFADIHFNDLQWECNYNRVAAYGQSKLANLLFTYEL MAB_0646c|M.abscessus_ATCC_199 EGSRVVTVSSIGHRIRADIHFDDLQWERDYDRVAAYGQSKLANLLFTYEL MMAR_0757|M.marinum_M PGSRVITVSSLGHRIRAAIHFDDLQWERSYNRVAAYGQSKLANLLFTYEL MUL_1391|M.ulcerans_Agy99 PGSRVITVSSLGHRIRAAIHFDDLQWERSYNRVAAYGQSKLANLLFTYEL MAV_4710|M.avium_104 RDSRVVTVSSLGHRLRAAIHFDDLHWERRYDRVAAYGQSKLANLLFTYEL TH_4179|M.thermoresistible__bu DGSRVVTVASIAHRNMADIHFDDLQWERGYHRVAAYGQSKLANLMFAYEL Mflv_0143|M.gilvum_PYR-GCK PGSRIVTVSSNGHKMGGAIHWDDLQWERSYNRMGAYTQSKLANLLFTYEL Mvan_0762|M.vanbaalenii_PYR-1 DGARIVTVSSNGHKMGGAIHWDDLQWERSYSRMGAYSQSKLANLLFTYEL .:*::*::* .*: . **::**:** * *:.** *:*****:*:*** Mb0069|M.bovis_AF2122/97 QRRLAPG--GTTIAVASHPGVSNTELVRNMPRPLV-AVAAILAP-LMQDA Rv0068|M.tuberculosis_H37Rv QRRLAPG--GTTIAVASHPGVSNTEVVRNMPRPLV-AVAAILAP-LMQDA MSMEG_0876|M.smegmatis_MC2_155 QRRLT-G--HQTTALAAHPGASNTELARHLPG----ALERLVTP-LAQDA MLBr_00315|M.leprae_Br4923 QRRLATR--QTTIAVAAHPGGSRTELTRTLPALIA-PIFSVAELFLTQDA MAB_0646c|M.abscessus_ATCC_199 QRRLA-G--TNTVALAAHPGGSNTELARNSPLWVR-AVFDVVAPVLVQGA MMAR_0757|M.marinum_M QRRLAADSQAATIAVAAHPGGSNTELARNLPRMLV-PLANILGPALFQSA MUL_1391|M.ulcerans_Agy99 QRRLAADSQAATIAVAAHPGDSNTELARNLPRMLV-PLANILGPALFQSA MAV_4710|M.avium_104 QRRLAAAPDAKTIAVAAHPGGSNTELARHLPGIFR-PVQAVLGPVLFQSP TH_4179|M.thermoresistible__bu QRRLSAK-NAPTISVAAHPGVSNTELTRYIPGARL-PGVSLLAGLLTNSP Mflv_0143|M.gilvum_PYR-GCK QRRLAPR--GKTIAVAAHPGTSTTELARNLPRPVERAFLAAAPVLFAQTA Mvan_0762|M.vanbaalenii_PYR-1 QRRLAPR--GKTIAVAAHPGTSSTELGRNLPAALQPALNRLAP-LLAQSP ****: * ::*:*** * **: * * . : : . Mb0069|M.bovis_AF2122/97 ELGALPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEQLQR Rv0068|M.tuberculosis_H37Rv ELGALPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEQLQR MSMEG_0876|M.smegmatis_MC2_155 ALGALPTLRAATDPGALGGQYFGPDGIGETRGYPKVVASSAQSHDADLQR MLBr_00315|M.leprae_Br4923 ATGALPTLRAATDAAVLGGQYFGPDGFAEIRGHPKVVASNGKSHDVDRQL MAB_0646c|M.abscessus_ATCC_199 DMGALPTLRAATDPAALGGQYYGPDGFMEQRGNPKVVASSEQSYNLDLQR MMAR_0757|M.marinum_M QMGALPTLRAATDPSVAGGQYYGPDGFAEQRGHPKIVQSSAQSHDEDLQR MUL_1391|M.ulcerans_Agy99 QMGALPTLRTATDPSAAGGQYYGPDGFAEQRGHPKIVQSSAQSHDEDLQR MAV_4710|M.avium_104 AMGALPTLRAATDPAVQGAQYYGPDGFLEQRGRPKLVESSAQSHDEQLQR TH_4179|M.thermoresistible__bu AVGALATLRAATDPEVKGGQYYGPDGFQEIRGHPVLVGSSAKSRDEDIQR Mflv_0143|M.gilvum_PYR-GCK DRGALPTLRAAADPGVLGGQYYGPDGLGQQRGAPVVVASSAQSYDVDQQR Mvan_0762|M.vanbaalenii_PYR-1 AAGALPTLRAATDPSVLGGQYYGPDGIGQQRGNPVVVASSNQSYDMALQR ***.***:*:*. . *.**:****: : ** * :* *. :* : * Mb0069|M.bovis_AF2122/97 RLWAVSEELTGVVYPVG------ Rv0068|M.tuberculosis_H37Rv RLWAVSEELTGVVYPVG------ MSMEG_0876|M.smegmatis_MC2_155 RLWAVSEELTGVTFPVGEALQQA MLBr_00315|M.leprae_Br4923 RLWAVSEELTGVVYPVG------ MAB_0646c|M.abscessus_ATCC_199 RLWSVSEELTDVVFPVK------ MMAR_0757|M.marinum_M RLWTVSEELTGVSFPV------- MUL_1391|M.ulcerans_Agy99 RLWTVSEELTGVSFPV------- MAV_4710|M.avium_104 RLWAVSEELTGVHFPV------- TH_4179|M.thermoresistible__bu RLWTVSEELTGVTFPV------- Mflv_0143|M.gilvum_PYR-GCK RLWEISEELTKVTFPDL------ Mvan_0762|M.vanbaalenii_PYR-1 RLWTVSEELTGVTFPVPVLS--- *** :***** * :*