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VTVHWTTADIPDQTGRVAVVTGANTGLGLETARALAAAGAQVVLAVRDPDKGAAAADDITKGAAGSNLAL QRLDLSSLSDIRSAARQLGADYPRIDLLINNAGVMYPPKSLTADGFELQFGTNHLGHFALTGLLLENLTA VPDSRVVIVSSNGHKFRAAIHFDDLQWERGYSRVGAYAQSKLANLLFTYELQRRLQAAGAETVALAAHPG ASGTELMRHITFGPEALTAAALKIAQSPAMGALPSLRAATDPAAQGGQYYGPSGFGEFRGYPKVVRSSKQ SHDKVLQQRLWSVSEELTGVRFPV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0643 | - | - | 100% (304) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0646c | - | e-108 | 68.09% (304) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_1144c | - | 2e-61 | 46.75% (308) | short-chain dehydrogenase/reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0069 | - | 1e-112 | 67.67% (300) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_0151 | - | 1e-110 | 65.69% (306) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv0068 | - | 1e-112 | 67.33% (300) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_00315 | - | 1e-103 | 65.12% (301) | short chain dehydrogenase |
| M. marinum M | MMAR_0757 | - | 1e-110 | 66.67% (306) | dehydrogenase/reductase |
| M. avium 104 | MAV_4710 | - | 1e-109 | 67.66% (303) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_0876 | - | 1e-115 | 70.67% (300) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_4179 | - | 1e-108 | 64.71% (306) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_1391 | - | 1e-109 | 66.67% (306) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_0762 | - | 1e-107 | 67.11% (301) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0069|M.bovis_AF2122/97 -------MTKWTAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVL
Rv0068|M.tuberculosis_H37Rv -------MTKWTAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVL
MSMEG_0876|M.smegmatis_MC2_155 -------MTKWTTARIPDQTGRVAIVTGANTGLGLETAKALAAKGAHVVL
MLBr_00315|M.leprae_Br4923 -------MAKWTTADIPDQTGRVAVITGANTGLGYQTALALAEHGAHVVL
MAB_0643|M.abscessus_ATCC_1997 ------MTVHWTTADIPDQTGRVAVVTGANTGLGLETARALAAAGAQVVL
Mvan_0762|M.vanbaalenii_PYR-1 -------MTDWTTADIPDQTGRTAVITGANTGLGFETAKALAAGGARVVL
MMAR_0757|M.marinum_M MSANGKAKSHWSASDIPDQSGRVVVVTGANTGLGYHTAEALAGRGAHVVL
MUL_1391|M.ulcerans_Agy99 MSAKGKAKSHWSASDIPDQSGRVVVVTGANTGLGYHTAEALADRGAHVVL
MAV_4710|M.avium_104 MAPHDKRHRDWSEADVGDQSGRVVVITGANTGIGYETAAVLAHRGAHVVL
Mflv_0151|M.gilvum_PYR-GCK ------MTSKWTAADVPDQSGRVAVVTGANTGIGYETAEVLAGKGARVVI
TH_4179|M.thermoresistible__bu ------MTGKWTARDVPDQTGRTAVITGANTGLGFETAKVLAEKGAHVVL
.*: : **:**..::******:* .** .** **:**:
Mb0069|M.bovis_AF2122/97 AVRNLDKGKQAAARITEATPGAEVELQELDLTSLASVRAAAAQLKSDHQR
Rv0068|M.tuberculosis_H37Rv AVRNLDKGKQAAARITEATPGAEVELQELDLTSLASVRAAAAQLKSDHQR
MSMEG_0876|M.smegmatis_MC2_155 AVRNLDKGKAAVDWIARSAPTADLELQQLDLGSLASVRAAADDLKGKFDR
MLBr_00315|M.leprae_Br4923 AVRNLDKGKDAAARITATSAQNNVALQELDLASLESVRAAAKQLRSDYDH
MAB_0643|M.abscessus_ATCC_1997 AVRDPDKGAAAADDITKGAAGSNLALQRLDLSSLSDIRSAARQLGADYPR
Mvan_0762|M.vanbaalenii_PYR-1 AVRDTEKGAQAAAKMAG-----DVDVQQLDLTSLASIRSAADALKSRFDH
MMAR_0757|M.marinum_M AVRNPEKGNAAVAQIVAAKPQADVTLQALDLSSLDSVRSAADALRSAYPR
MUL_1391|M.ulcerans_Agy99 AVRNPEKGNAAVAQIVAAKPQADVTLQALDLSSLDSVRSAADALRSAYPR
MAV_4710|M.avium_104 AVRDLEKGNAALSRIVAASPNADVTLQQLDLASLASVRSAAEALRAAYPR
Mflv_0151|M.gilvum_PYR-GCK AVRDAGKGQKALDAITRKHPGAAVSLQELDLSSLGSVRRATDALRSAHPR
TH_4179|M.thermoresistible__bu AVRDPDKGRRAADRITAAAPHADVTVRQLDLTSLDNIRRAADDLRAGYPR
***: ** * :. : :: *** ** .:* *: * . . :
Mb0069|M.bovis_AF2122/97 IDLLINNAGVMYTPRQTTADGFEMQFGTNHLGHFALTGLLIDRLLPVAGS
Rv0068|M.tuberculosis_H37Rv IDLLINNAGVMYTPRQTTADGFEMQFGTNHLGHFALTGLLIDRLLPVAGS
MSMEG_0876|M.smegmatis_MC2_155 IDLLVNNAGVMWPPRQTTADGFELQFGTNHLGHFALTGLLLDRMLTVPGS
MLBr_00315|M.leprae_Br4923 IDLLINNAGVMWTPKSTTKDGFELQFGTNHLGHFAFTGLLLDRLLPIVGS
MAB_0643|M.abscessus_ATCC_1997 IDLLINNAGVMYPPKSLTADGFELQFGTNHLGHFALTGLLLENLTAVPDS
Mvan_0762|M.vanbaalenii_PYR-1 IDLLINNAGVMTTPKGTTADGFELQFGTNHLGHFAFTGLLLDKLLDVDGA
MMAR_0757|M.marinum_M IDLLINNAGVMWTPKQVTKDGFEMQFGTNHLGHFALTGLLLDHLLPVPGS
MUL_1391|M.ulcerans_Agy99 IDLLINNAGVMWTPKQVTKDGFEMQFGTNHLGHFALTGLLLDHLLPVPGS
MAV_4710|M.avium_104 IDLLINNAGVMWTPKQVTEDGFELQFGTNHLGHFALTGLLLDHLLGVRDS
Mflv_0151|M.gilvum_PYR-GCK IDLLINNAGVMYPPKQVTRDGFELQFGTNHLGHFAFTGLLLDNLLDVPGS
TH_4179|M.thermoresistible__bu IDLLINNAGVMYPPRQTTRDGFELQFGTNHLGHFALTGQLLDNILPVDGS
****:****** .*: * ****:***********:** *::.: : .:
Mb0069|M.bovis_AF2122/97 RVVTISSVGHRIRAAIHFDDLQWERRYRRVAAYGQAKLANLLFTYELQRR
Rv0068|M.tuberculosis_H37Rv RVVTISSVGHRIRAAIHFDDLQWERRYRRVAAYGQAKLANLLFTYELQRR
MSMEG_0876|M.smegmatis_MC2_155 RVVTVSSQGHRILAAIHFDDLQWERRYNRVAAYGQSKLANLLFTYELQRR
MLBr_00315|M.leprae_Br4923 RVITVSSLSHRLFADIHFNDLQWECNYNRVAAYGQSKLANLLFTYELQRR
MAB_0643|M.abscessus_ATCC_1997 RVVIVSSNGHKFRAAIHFDDLQWERGYSRVGAYAQSKLANLLFTYELQRR
Mvan_0762|M.vanbaalenii_PYR-1 RIVTVSSNGHKMGGAIHWDDLQWERSYSRMGAYSQSKLANLLFTYELQRR
MMAR_0757|M.marinum_M RVITVSSLGHRIRAAIHFDDLQWERSYNRVAAYGQSKLANLLFTYELQRR
MUL_1391|M.ulcerans_Agy99 RVITVSSLGHRIRAAIHFDDLQWERSYNRVAAYGQSKLANLLFTYELQRR
MAV_4710|M.avium_104 RVVTVSSLGHRLRAAIHFDDLHWERRYDRVAAYGQSKLANLLFTYELQRR
Mflv_0151|M.gilvum_PYR-GCK RVVTVASLAHKNLADIHFDDLQWERKYNRVAAYGQSKLANLMFTYELQRR
TH_4179|M.thermoresistible__bu RVVTVASIAHRNMADIHFDDLQWERGYHRVAAYGQSKLANLMFAYELQRR
*:: ::* .*: . **::**:** * *:.**.*:*****:*:******
Mb0069|M.bovis_AF2122/97 LAPGG--TTIAVASHPGVSNTELVRNMPRPLVAVAAILAP-LMQDAELGA
Rv0068|M.tuberculosis_H37Rv LAPGG--TTIAVASHPGVSNTEVVRNMPRPLVAVAAILAP-LMQDAELGA
MSMEG_0876|M.smegmatis_MC2_155 LT-GH--QTTALAAHPGASNTELARHLPG---ALERLVTP-LAQDAALGA
MLBr_00315|M.leprae_Br4923 LATRQ--TTIAVAAHPGGSRTELTRTLPALIAPIFSVAELFLTQDAATGA
MAB_0643|M.abscessus_ATCC_1997 LQAAGA-ETVALAAHPGASGTELMRHITFG-PEALTAAALKIAQSPAMGA
Mvan_0762|M.vanbaalenii_PYR-1 LAPRG--KTIAVAAHPGTSSTELGRNLPAALQPALNRLAPLLAQSPAAGA
MMAR_0757|M.marinum_M LAADSQAATIAVAAHPGGSNTELARNLPRMLVPLANILGPALFQSAQMGA
MUL_1391|M.ulcerans_Agy99 LAADSQAATIAVAAHPGDSNTELARNLPRMLVPLANILGPALFQSAQMGA
MAV_4710|M.avium_104 LAAAPDAKTIAVAAHPGGSNTELARHLPGIFRPVQAVLGPVLFQSPAMGA
Mflv_0151|M.gilvum_PYR-GCK LAARG-APTIAVAAHPGISNTELMRHVPGTSLPGVMKLAGLVTNTPAVGA
TH_4179|M.thermoresistible__bu LSAKN-APTISVAAHPGVSNTELTRYIPGARLPGVSLLAGLLTNSPAVGA
* * ::*:*** * **: * :. : : . **
Mb0069|M.bovis_AF2122/97 LPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEQLQRRLWA
Rv0068|M.tuberculosis_H37Rv LPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEQLQRRLWA
MSMEG_0876|M.smegmatis_MC2_155 LPTLRAATDPGALGGQYFGPDGIGETRGYPKVVASSAQSHDADLQRRLWA
MLBr_00315|M.leprae_Br4923 LPTLRAATDAAVLGGQYFGPDGFAEIRGHPKVVASNGKSHDVDRQLRLWA
MAB_0643|M.abscessus_ATCC_1997 LPSLRAATDPAAQGGQYYGPSGFGEFRGYPKVVRSSKQSHDKVLQQRLWS
Mvan_0762|M.vanbaalenii_PYR-1 LPTLRAATDPSVLGGQYYGPDGIGQQRGNPVVVASSNQSYDMALQRRLWT
MMAR_0757|M.marinum_M LPTLRAATDPSVAGGQYYGPDGFAEQRGHPKIVQSSAQSHDEDLQRRLWT
MUL_1391|M.ulcerans_Agy99 LPTLRTATDPSAAGGQYYGPDGFAEQRGHPKIVQSSAQSHDEDLQRRLWT
MAV_4710|M.avium_104 LPTLRAATDPAVQGAQYYGPDGFLEQRGRPKLVESSAQSHDEQLQRRLWA
Mflv_0151|M.gilvum_PYR-GCK LPTVRAATDPGVTGGQYYGPSGFNEMVGHPVLVTSNKKSHDVAVQQRLWT
TH_4179|M.thermoresistible__bu LATLRAATDPEVKGGQYYGPDGFQEIRGHPVLVGSSAKSRDEDIQRRLWT
*.::*:***. . *.**:**.*: : * * :* *. :* * * ***:
Mb0069|M.bovis_AF2122/97 VSEELTGVVYPVG------
Rv0068|M.tuberculosis_H37Rv VSEELTGVVYPVG------
MSMEG_0876|M.smegmatis_MC2_155 VSEELTGVTFPVGEALQQA
MLBr_00315|M.leprae_Br4923 VSEELTGVVYPVG------
MAB_0643|M.abscessus_ATCC_1997 VSEELTGVRFPV-------
Mvan_0762|M.vanbaalenii_PYR-1 VSEELTGVTFPVPVLS---
MMAR_0757|M.marinum_M VSEELTGVSFPV-------
MUL_1391|M.ulcerans_Agy99 VSEELTGVSFPV-------
MAV_4710|M.avium_104 VSEELTGVHFPV-------
Mflv_0151|M.gilvum_PYR-GCK VSEELTGVKYGV-------
TH_4179|M.thermoresistible__bu VSEELTGVTFPV-------
******** : *