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NRYVKRGSVGVSIFAVSAAAAVLANPSENSAIAAAAGCPDVDVSFARGTNDSPGLGDVGKAFTDELTDRL AGKSVDIYAVNYPASFDWVRAGDGANDMSYHVQEVARNCPNTQFVLGGFSQGAAVVDVLFGTNGTGLTFN NPLPTDLEKRVAAIVLIGNPKNWQVAGMNLDLSIRDDQRSKIIDICNPGDGICDPNGGGLGPHMQYKSDG SADKAADFVAGRLAAVAASSSAAAASSSTSTTASGVPASTSKSANPLSATTAPAPTSASPAPASSPSSST PKPVAASTSRRVPAWMMPATDAPAAEVPAAVTSTIPAPDPARHGPLPGPGGQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3809c | - | - | 100% (333) | cutinase Cut4 |
| M. abscessus ATCC 19977 | MAB_4405 | - | 2e-43 | 46.89% (177) | serine esterase cutinase family |
| M. abscessus ATCC 19977 | MAB_3766 | - | 9e-36 | 40.64% (219) | cutinase cut3 precursor |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3482 | cut4 | 7e-40 | 44.08% (211) | cutinase precursor CUT4 |
| M. gilvum PYR-GCK | Mflv_4439 | - | 3e-44 | 43.36% (226) | cutinase |
| M. tuberculosis H37Rv | Rv3452 | cut4 | 7e-40 | 44.08% (211) | cutinase precursor CUT4 |
| M. leprae Br4923 | MLBr_00099 | - | 9e-05 | 26.45% (155) | hypothetical protein MLBr_00099 |
| M. marinum M | MMAR_1098 | cut3 | 4e-43 | 39.11% (271) | cutinase precursor, Cut3 |
| M. avium 104 | MAV_4396 | - | 6e-43 | 44.65% (215) | cutinase |
| M. smegmatis MC2 155 | MSMEG_1528 | - | 4e-47 | 46.26% (214) | cutinase |
| M. thermoresistible (build 8) | TH_4127 | - | 3e-35 | 41.43% (210) | PUTATIVE serine esterase, cutinase family protein |
| M. ulcerans Agy99 | MUL_0856 | cut3 | 5e-42 | 38.38% (271) | cutinase precursor, Cut3 |
| M. vanbaalenii PYR-1 | Mvan_1441 | - | 1e-45 | 45.87% (218) | cutinase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3482|M.bovis_AF2122/97 --MIPRPQPHSGRWRAGAARRLTSLVAAAFAAATLLLTP-----------
Rv3452|M.tuberculosis_H37Rv --MIPRPQPHSGRWRAGAARRLTSLVAAAFAAATLLLTP-----------
MAV_4396|M.avium_104 ----------------------MGLGVGLLAGAAVLIAP-----------
MMAR_1098|M.marinum_M ----------------MNKHPLAVLAGALVTATGLLAAP-----------
MUL_0856|M.ulcerans_Agy99 ----------------MNKHPLAVLAGALVTATGLLAAP-----------
MSMEG_1528|M.smegmatis_MC2_155 ------------MSLDLVFRRARLVAAAALIATVMLAAPLAA--------
Mvan_1441|M.vanbaalenii_PYR-1 ----------MMIDLDAPARRATGVLAAILVAAATLVA------------
MAB_3809c|M.abscessus_ATCC_199 ------------MNRYVKRGSVGVSIFAVSAAAAVLANP-----------
TH_4127|M.thermoresistible__bu ----------------------------VLGSAALLAGVP----------
Mflv_4439|M.gilvum_PYR-GCK --------MGLSECLSGVTAPGLALAAGLLLAPHAFAQPALTPAPGPA--
MLBr_00099|M.leprae_Br4923 MVEKVPRKRHRVLAWTAALSMAAVVALAIVAVVILLRSAESPRSSLPPGV
:
Mb3482|M.bovis_AF2122/97 -------ALA----PPASAG-CPDAEVVFARGTGEPPGLG------RVGQ
Rv3452|M.tuberculosis_H37Rv -------ALA----PPASAG-CPDAEVVFARGTGEPPGLG------RVGQ
MAV_4396|M.avium_104 -------QLI----PLASAS-CPGVEVVFARGTDEPPGVG------KVGG
MMAR_1098|M.marinum_M -------SITGTAIPSASAADCPDAEVVFARGTSEPPGIG------RVGE
MUL_0856|M.ulcerans_Agy99 -------SITGTAIPSASAADCPDAEVVFPRGTSEPPGIG------RVGE
MSMEG_1528|M.smegmatis_MC2_155 -------HAPTGALGAARAADCPDIEVVFARGTDESPGIG------RIGN
Mvan_1441|M.vanbaalenii_PYR-1 --------APV-QIPAAHAQGCPDIEVVFARGTDEPPGLG------RVGA
MAB_3809c|M.abscessus_ATCC_199 -------SENS---AIAAAAGCPDVDVSFARGTNDSPGLG------DVGK
TH_4127|M.thermoresistible__bu -------------APTAAAIPCSDVEVVFARGTSEPPGVG------RVGQ
Mflv_4439|M.gilvum_PYR-GCK ---PPPIAAPAPEPLAAPVAGCPDVEIVFARGTTEAPGLG------AMGQ
MLBr_00099|M.leprae_Br4923 LPIPSTAPHPRKPRPAFQDVSCPDVQLLVVPGTWESSLQDNPLDPVQFPD
*.. :: . ** :.. . .
Mb3482|M.bovis_AF2122/97 AFVS----SLRQQTN-KSIGTYGVNYPANGDFLAAAD-----------GA
Rv3452|M.tuberculosis_H37Rv AFVS----SLRQQTN-KSIGTYGVNYPANGDFLAAAD-----------GA
MAV_4396|M.avium_104 AFVS----SLREQTR-KSVGAYGVNYPANKDFLAAAD-----------GA
MMAR_1098|M.marinum_M AFVD----SLRQQTG-KNIGVYAVNYPASRLQLHGGD-----------GA
MUL_0856|M.ulcerans_Agy99 AFVD----SLRQQTG-KNIGVYAVNYPASRLQLHGGD-----------GA
MSMEG_1528|M.smegmatis_MC2_155 AFVQ----ALRGKVGGRSVGTYAVNYPASYDFLAAAD-----------GA
Mvan_1441|M.vanbaalenii_PYR-1 AFVD----SLRGRVGGRSVGTYAVNYPASFDFLAAAA-----------GA
MAB_3809c|M.abscessus_ATCC_199 AFTD----ELTDRLAGKSVDIYAVNYPASFDWVRAGD-----------GA
TH_4127|M.thermoresistible__bu ALAN----ALQARLPGRTVSTYGVSYPATYDFLAATD-----------GA
Mflv_4439|M.gilvum_PYR-GCK AFVE----DLRSRLGGKTVGVYAVDYPASPDFPTAVE-----------GI
MLBr_00099|M.leprae_Br4923 ALLRNSTMTIGQQFPTSRVQTYTIPYTAQFHNPLSGDKQMTYNDSRAEGT
*: : : : * : *.* . *
Mb3482|M.bovis_AF2122/97 NDASDHIQQMASACRATRLVLGGYSQGAAVIDIVTAAPLPG---------
Rv3452|M.tuberculosis_H37Rv NDASDHIQQMASACRATRLVLGGYSQGAAVIDIVTAAPLPG---------
MAV_4396|M.avium_104 NDASNHIQQMAGNCPNTKLVLGGYSQGAAVIDIVTAAPVPG---------
MMAR_1098|M.marinum_M NDVISHVKSMASSCPNTKIVLGGYSQGADVIDIVAGVPLAG---------
MUL_0856|M.ulcerans_Agy99 NDVISHVKSMASSCPNTKIVQGGYSQGADVIDIVAGVPLAG---------
MSMEG_1528|M.smegmatis_MC2_155 NDASGHVQWMVNNCPNTRLVLGGYSQGAAVIDVIAAVPFPA---------
Mvan_1441|M.vanbaalenii_PYR-1 NDASLHIQYMMANCPRTRLVLGGYSQGAAVIDVIAAVPIPA---------
MAB_3809c|M.abscessus_ATCC_199 NDMSYHVQEVARNCPNTQFVLGGFSQGAAVVDVLFGTNGTG---------
TH_4127|M.thermoresistible__bu NDATARITTLAQQCPSTRVVLGGYSQGAAVVDMLGGLPPLGD--------
Mflv_4439|M.gilvum_PYR-GCK ADASTHVQQIAMNCPDTKLVLGGYSQGAAVMGFVTTELIPDG--------
MLBr_00099|M.leprae_Br4923 RAMVQEMINVNNKCPLTSYVLVGFSQGAVIAGDITSDIGNGHGPVDDDLV
.: : * * * *:**** : . :
Mb3482|M.bovis_AF2122/97 --------------LGFT-QPLPP--AADDHIAAIALFGNPSGRAGG---
Rv3452|M.tuberculosis_H37Rv --------------LGFT-QPLPP--AADDHIAAIALFGNPSGRAGG---
MAV_4396|M.avium_104 --------------LGFR-NPLPP--QAADHVAAVALFGNPSGRAGR---
MMAR_1098|M.marinum_M --------------ISFG-NELPA--QYADNIAAVAVFGNVANRSGG---
MUL_0856|M.ulcerans_Agy99 --------------ISFG-NELPA--QYADNIAAVAVFGNVANRSGG---
MSMEG_1528|M.smegmatis_MC2_155 --------------IGFN-APLPA--NVPEHVAAVAVFGNPSAKLG----
Mvan_1441|M.vanbaalenii_PYR-1 --------------VGFN-APLPP--NTPDFVAAIAVFGNPSTKLG----
MAB_3809c|M.abscessus_ATCC_199 --------------LTFN-NPLPT--DLEKRVAAIVLIGNPKNWQVAGMN
TH_4127|M.thermoresistible__bu ------------R-VGLVGSALPT--GSVGNVAAVAVFGNPSAKFGR---
Mflv_4439|M.gilvum_PYR-GCK ------------VSLSEVPAPMPP--DIADHVAAVALLGAPSDRFMDMIK
MLBr_00099|M.leprae_Br4923 LGVTLIADGRRQQGVGNDIGPNPPGEGAEVTLHEVPVLSGLGMTMTG---
: *. : : ::.
Mb3482|M.bovis_AF2122/97 -LMSALTPQFGSKTINLCNNGDPICSDG--NRWRAHLG-YVPGMTNQAAR
Rv3452|M.tuberculosis_H37Rv -LMSALTPQFGSKTINLCNNGDPICSDG--NRWRAHLG-YVPGMTNQAAR
MAV_4396|M.avium_104 -LMSALTPDFSGKTIDLCNPGDPICSGG--YQWASHLS-YVPGLTNQAAR
MMAR_1098|M.marinum_M -SLTTQSSLLGSKSIDLCNPSDPICHSGPGNDWNGHTDGYVPTYTTQAAS
MUL_0856|M.ulcerans_Agy99 -SLTTQSSLLGSKSIDLCNPSDPICHSGPGNDWNGHTDGYVPTYTTQAAS
MSMEG_1528|M.smegmatis_MC2_155 -LPLTASPVYGSRAIDLCNAGDPVCGSG--DSVPAHRAYD-GGPANQAAA
Mvan_1441|M.vanbaalenii_PYR-1 -IPITASPVWGSRSIDLCNGLDPVCSGG--DDIAAHSNYGPGMFTDQAAA
MAB_3809c|M.abscessus_ATCC_199 -LDLSIRDDQRSKIIDICNPGDGICDPN-GGGLGPHMQYKSDGSADKAAD
TH_4127|M.thermoresistible__bu --PINTSPVFGGRGIDLCSDGDPICSNG--RNPFAHTNYETSVHIETAAD
Mflv_4439|M.gilvum_PYR-GCK QPPVTIGALYQPKTLELCVPGDFVCSPG--NDLGAHARYISDGLVVQAAD
MLBr_00099|M.leprae_Br4923 -ARPGGFGVLHSRTNEICAPGDLICAAPAEAFSVANLPATLNTLASGAGQ
: ::* * :* : *.
Mb3482|M.bovis_AF2122/97 FVASRI--------------------------------------------
Rv3452|M.tuberculosis_H37Rv FVASRI--------------------------------------------
MAV_4396|M.avium_104 FVAARV--------------------------------------------
MMAR_1098|M.marinum_M FVAAKLAASSMAPVVQLPGPVPRAPGP--------------APQAPGPAT
MUL_0856|M.ulcerans_Agy99 FVAAKLAASSMAPVVRLPGPVPRAPGP--------------APQAPGPAT
MSMEG_1528|M.smegmatis_MC2_155 FVAGLL--------------------------------------------
Mvan_1441|M.vanbaalenii_PYR-1 FVAGRL--------------------------------------------
MAB_3809c|M.abscessus_ATCC_199 FVAGRLAAVAASSSAAAASSSTSTTASGVPASTSKSANPLSATTAPAPTS
TH_4127|M.thermoresistible__bu FAAGLI--------------------------------------------
Mflv_4439|M.gilvum_PYR-GCK FAVGKLAETPAESGGAPA--------------------------------
MLBr_00099|M.leprae_Br4923 PIHAMYATAQFWDLDGAPATVWTLNWVHRLIEGAPHPKHG----------
.
Mb3482|M.bovis_AF2122/97 --------------------------------------------------
Rv3452|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4396|M.avium_104 --------------------------------------------------
MMAR_1098|M.marinum_M ASPG---TPVGATGTLVGAH------------------------------
MUL_0856|M.ulcerans_Agy99 ASPG---TPVGATGTLVGAH------------------------------
MSMEG_1528|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1441|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3809c|M.abscessus_ATCC_199 ASPAPASSPSSSTPKPVAASTSRRVPAWMMPATDAPAAEVPAAVTSTIPA
TH_4127|M.thermoresistible__bu --------------------------------------------------
Mflv_4439|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_00099|M.leprae_Br4923 --------------------------------------------------
Mb3482|M.bovis_AF2122/97 ---------------
Rv3452|M.tuberculosis_H37Rv ---------------
MAV_4396|M.avium_104 ---------------
MMAR_1098|M.marinum_M ---------------
MUL_0856|M.ulcerans_Agy99 ---------------
MSMEG_1528|M.smegmatis_MC2_155 ---------------
Mvan_1441|M.vanbaalenii_PYR-1 ---------------
MAB_3809c|M.abscessus_ATCC_199 PDPARHGPLPGPGGQ
TH_4127|M.thermoresistible__bu ---------------
Mflv_4439|M.gilvum_PYR-GCK ---------------
MLBr_00099|M.leprae_Br4923 ---------------