For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VARGETRSAALLAVALQVLIRDGYDRFSMDSVAALAHASKTTIYRRWSNKAELIKAALDAHDASFNDEVF DTGGLRTDLIATMGMLRRKAQALPPTLYPDLIRAMEHDETLSDAIRRHLADPGLSPFDAPLSRAVGRGEA GVDVDRQLIHDVAEAMLTHRLTLGGPLDDAFIGRLVDDVLLVLIRPGAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1497c | - | - | 100% (190) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0989 | - | 1e-16 | 35.33% (184) | putative HTH-type transcriptional regulator TetR |
| M. abscessus ATCC 19977 | MAB_3151 | - | 2e-16 | 32.96% (179) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1581 | - | 9e-16 | 32.95% (176) | regulatory protein |
| M. gilvum PYR-GCK | Mflv_3683 | - | 2e-18 | 31.89% (185) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1556 | - | 1e-15 | 32.95% (176) | regulatory protein |
| M. leprae Br4923 | MLBr_00815 | - | 1e-05 | 38.60% (57) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_1695 | - | 1e-16 | 34.66% (176) | regulatory protein |
| M. avium 104 | MAV_4754 | - | 4e-19 | 35.68% (185) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0465 | - | 2e-17 | 34.04% (188) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0688 | - | 3e-10 | 28.49% (186) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_1934 | - | 7e-17 | 34.66% (176) | regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_2727 | - | 4e-22 | 34.05% (185) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_4754|M.avium_104 --------------MGQPQSQMEPESKLRQRTEGRLDRSRDPAILDAALA
MSMEG_0465|M.smegmatis_MC2_155 --------------------MKATDSKLRQRTDGRLDRTRDPAILDAALA
MAB_1497c|M.abscessus_ATCC_199 -----------------------------MVARG---ETRSAALLAVALQ
Mflv_3683|M.gilvum_PYR-GCK ---------------------------MMTRRRG---AELDAAIRSAVLD
Mvan_2727|M.vanbaalenii_PYR-1 ----------------------------MGRRRG---AELDAAIRAAVLE
Mb1581|M.bovis_AF2122/97 -------------------MVGAVTQIADRPTDPSPWSPRETELLAVTLR
Rv1556|M.tuberculosis_H37Rv -------------------MVGAVTQIADRPTDPSPWSPRETELLAVTLR
MMAR_1695|M.marinum_M -----------------------MTQTADRSAQVSPWSPREAELLAVTLQ
MUL_1934|M.ulcerans_Agy99 --------------------MGAMTQTADRSAQVSPWSPREAELLAVTLQ
TH_0688|M.thermoresistible__bu ------------------MTTNSTSVDKAAGAGRPRDPRIDGAILRATAD
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
: ..
MAV_4754|M.avium_104 ALAEHGYDATNMNDIAARAGVGKAAIYRRWSSKAALMTDALIYWRPELLN
MSMEG_0465|M.smegmatis_MC2_155 ALAENGYAGTNMDDIASRAGVGKAAIYRRWSSKAALITDALVYWKPALLI
MAB_1497c|M.abscessus_ATCC_199 VLIRDGYDRFSMDSVAALAHASKTTIYRRWSNKAELIKAALDAHD-ASFN
Mflv_3683|M.gilvum_PYR-GCK LLAGHGPEAVTMDAVAVAAGTSKPVLYRRWPDRRALLRDTLMAVASTSFP
Mvan_2727|M.vanbaalenii_PYR-1 LLAEHGPDGVTMDAVAVTAQTSKPVLYRRWPDRRALLRDTLLGIATSAFP
Mb1581|M.bovis_AF2122/97 LLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVAV
Rv1556|M.tuberculosis_H37Rv LLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVAV
MMAR_1695|M.marinum_M LLQEHGYDRLTIDAVANTARASKATVYRRWPSKAELVLAAFIEGVRQVAV
MUL_1934|M.ulcerans_Agy99 LLQEHGYDRLTIDAVANTARASKATVYRRWPSKAELVLAAFIEGVRQVAV
TH_0688|M.thermoresistible__bu LLVEIGYSNLTMSAVAERAGTTKTALYRRWSSKPELVYAATAPTDPVDTV
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
: * :. :* * . *..:*:::..: * .
MAV_4754|M.avium_104 DDAPDTGSLAGDLDAIVKRAKRNDNALISNDLVLRVALEAAHDPELATAL
MSMEG_0465|M.smegmatis_MC2_155 DDIPDTGSLEGDLNEIAERAARNADERITYDLILRVAVEAMNDSQLASAL
MAB_1497c|M.abscessus_ATCC_199 DEVFDTGGLRTDLIATMGMLRRKAQALPP-TLYPDLIRAMEHDETLSDAI
Mflv_3683|M.gilvum_PYR-GCK --RPDTGTFRGDLLAVLRAWAQLFTGDTG-PLMRSVIVAVASDPDLESTF
Mvan_2727|M.vanbaalenii_PYR-1 --TVDTGGFRGDMLAVLRAWAALFTGDSA-ALMRSAIGAVTADPELAATF
Mb1581|M.bovis_AF2122/97 P--PNTGNLRDDLLRLGELICREVGQHAS--TIRAVLVEVSRNPALNDVL
Rv1556|M.tuberculosis_H37Rv P--PNTGNLRDDLLRLGELICREVGQHAS--TIRAVLVEVSRNPALNDVL
MMAR_1695|M.marinum_M A--PNTGSLRDDLVKIGEGICGQAHQQAS--TIRAVLVEVSRHPALSDAL
MUL_1934|M.ulcerans_Agy99 A--PNTGSLRDDLVKIGEGICGQAHQQAS--TIRAVLVEVSRHPALSDAL
TH_0688|M.thermoresistible__bu ESSDDVAGIVRALIERNRQITATPAARAA---MPGLLVDMAADPRLHRGL
MLBr_00815|M.leprae_Br4923 SVQQALRTTTNNRQRLHAAVQAFFDFIEH--DGQGYRLIFENDNITEPRV
. .
MAV_4754|M.avium_104 NDLILFKGRRVLSAVLAQAADRGEIDPNRDWSLVADVLTAMGLLR--AIS
MSMEG_0465|M.smegmatis_MC2_155 DDLTLLRGRRTMTAILKNATARGEIAPDTDWSLVPDVLTAMLLMR--AIR
MAB_1497c|M.abscessus_ATCC_199 RRHLADPGLSPFDAPLSRAVGRGEAGVDVDRQLIHDVAEAMLTHR--LTL
Mflv_3683|M.gilvum_PYR-GCK RSDVLGMRKAEMTTLIGRAVERGEVRPDVPVELVRELGQSVLWHR--LLI
Mvan_2727|M.vanbaalenii_PYR-1 RTDVIGARKQEMDAIITRGVQRGEVRADVPVDLVRELGQSVLWHR--LLI
Mb1581|M.bovis_AF2122/97 QHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFR--SII
Rv1556|M.tuberculosis_H37Rv QHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFR--SII
MMAR_1695|M.marinum_M QRQFVDQRKALIQQVLQQAVDRGEITQAAITDELWDLLPGYLIFR--SII
MUL_1934|M.ulcerans_Agy99 QRQFVDQRKALIQQVLQQAVDRGEITQAAITDELWDLLPGYLIFR--SII
TH_0688|M.thermoresistible__bu LGRVG-SLVEALRRRLAEAAGRGEVQSGVDADRLTELIGGSVMFR--MVL
MLBr_00815|M.leprae_Br4923 AAQVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGISVDCARYWLD
: : .. :
MAV_4754|M.avium_104 -GQRVDGKFVRRVIDTLILPAVRAAPE---
MSMEG_0465|M.smegmatis_MC2_155 -GERVDANYVRKVIDTVIVPAVRATAY---
MAB_1497c|M.abscessus_ATCC_199 -GGPLDDAFIGRLVDDVLLVLIRPGAR---
Mflv_3683|M.gilvum_PYR-GCK TGDPITDELVTQLVDEVLIPVTRPYYDQ--
Mvan_2727|M.vanbaalenii_PYR-1 SGDPIDDEVVTRLVDEVLIPVTRPYYEV--
Mb1581|M.bovis_AF2122/97 PNRPPTQDTVQALVDDVILPSLTRSTG---
Rv1556|M.tuberculosis_H37Rv PNRPPTQDTVQALVDDVILPSLTRSTG---
MMAR_1695|M.marinum_M PNRPPTPHTVQLLVDDFIMPGLTQATG---
MUL_1934|M.ulcerans_Agy99 PNRPPTPHTVQLLVDDFIMPGLTQATG---
TH_0688|M.thermoresistible__bu HPDEPITERWADEVAAILIRGVTKEG----
MLBr_00815|M.leprae_Br4923 TNRPISKSDAVEGTVQFAWGGLSHVPLTRL
.