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MTDERRMRGRPPLPMETIVDAALQIVDEEGGEALSMRALARRLDSGTATIYRHFANRTEVVAHVVDRVFG EVQLDDPALARMPWQDACIVSSRALFDALRRHPNVAMLLADQIPVGPNVFMIREHTLTLCLQAGFSPAEA IRIYMTLGRYVLGFANQIGAEHRASEADIAMLTRLVENIDLASYPSTLATAGVTLVPLDEEFDFGLGLIV AGLEGLRHGE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4687 | - | - | 100% (220) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2380c | - | 8e-16 | 29.86% (221) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0856c | - | 2e-14 | 28.17% (213) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1388c | - | 1e-06 | 20.78% (154) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_2560 | - | 6e-10 | 27.15% (221) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1353c | - | 1e-06 | 20.78% (154) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_3679 | - | 8e-14 | 26.42% (212) | putative regulatory protein |
| M. avium 104 | MAV_5055 | - | 2e-09 | 28.08% (146) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0442 | - | 2e-16 | 29.33% (208) | tetracycline repressor domain-containing protein |
| M. thermoresistible (build 8) | TH_0654 | - | 9e-11 | 28.22% (202) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_3622 | - | 1e-13 | 26.42% (212) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_1315 | - | 2e-13 | 30.15% (199) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3679|M.marinum_M ---------------------------MFTLRTMYLSTVWEGDVRA---R
MUL_3622|M.ulcerans_Agy99 -------------------MISIRTSYVFTLRTMYLSTVWEGDVRA---R
Mb1388c|M.bovis_AF2122/97 --------------------------------MQTTPGKRQRRQRG---S
Rv1353c|M.tuberculosis_H37Rv --------------------------------MQTTPGKRQRRQRG---S
Mflv_2560|M.gilvum_PYR-GCK MTSLPPATIGRMDNPGSGSARSSAGDPVRTLELLWRVPAEARSGRGPKQR
TH_0654|M.thermoresistible__bu ------------------------------------------------VQ
MAV_5055|M.avium_104 -----------------------------------------MRRAG----
Mvan_1315|M.vanbaalenii_PYR-1 -----MSYAHGCTAVRLDRMTNEEERGTPPLPRALEVLWHDRAGGGRARR
MAB_4687|M.abscessus_ATCC_1997 -------------------------------------MTDERRMRGR-PP
MSMEG_0442|M.smegmatis_MC2_155 ------------------------------------------MGRPSTPI
MMAR_3679|M.marinum_M FTVSDIASAALAIVDQDGLSGLSMRSLAAALGTGPMTLYNYVRDRRELEA
MUL_3622|M.ulcerans_Agy99 FTVSDIASAALAIVDQDGLSGLSMRSLAAALGTGPMTLYNYVRDRRELEA
Mb1388c|M.bovis_AF2122/97 INPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLN
Rv1353c|M.tuberculosis_H37Rv INPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLN
Mflv_2560|M.gilvum_PYR-GCK TSVDAVVAAAVGIADTQGLSAVTIRAVAGVLGLAPMAIYTYVPGKAELLD
TH_0654|M.thermoresistible__bu LRKSDVVDAATAILDNYGIADLTTRRLARELGVTAGALYWHFANKQELLG
MAV_5055|M.avium_104 LKREAVVRAAVKIADAEGIEAISMRRVSQALGVTPMALYRYLPDKDALID
Mvan_1315|M.vanbaalenii_PYR-1 LSRQRIVEAAIELADRDGLGALSMARLAERLGCGTMSLYRHVANKDELVT
MAB_4687|M.abscessus_ATCC_1997 LPMETIVDAALQIVDEEGGEALSMRALARRLDSGTATIYRHFANRTEVVA
MSMEG_0442|M.smegmatis_MC2_155 LSTDRIATAALDLVNSTG--GFTIPGLARRLKVSPSSLYNHVAGREQIVE
. : .* : : . .: :. * ::* :. : :
MMAR_3679|M.marinum_M LVADAVVADVKVPAP---TDDWRADVHAIATAMWETMRQHPNAIPLVLTR
MUL_3622|M.ulcerans_Agy99 LVADAVVADVKVPAP---IDDWRADVHAIATAMWETMRQHPNAIPLVLTR
Mb1388c|M.bovis_AF2122/97 AMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIR
Rv1353c|M.tuberculosis_H37Rv AMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIR
Mflv_2560|M.gilvum_PYR-GCK LMLDSVYGQMSRGDLS--GLPWRHRVTAIADENRALLDEHPWVTQLATTR
TH_0654|M.thermoresistible__bu AVADRILTPVPAGEP---EPGWAERISSTAGRLRDALLSHTDGAELVSAT
MAV_5055|M.avium_104 VVVDESLAVVPVPDP---SGSVTAELLRCFGGLYDLLLDHPGLARAAGER
Mvan_1315|M.vanbaalenii_PYR-1 FMVSAAPGHPPGTTDR---ADWRDALTDWAVGLWDVYHRHPWILHATVIG
MAB_4687|M.abscessus_ATCC_1997 HVVDRVFGEVQLDDPALARMPWQDACIVSSRALFDALRRHPNVAMLLADQ
MSMEG_0442|M.smegmatis_MC2_155 LLRERAMSEVNLPDLDT-DRPWSDVVADIMRSYRRSFARYPRLIPLLTIH
: . .
MMAR_3679|M.marinum_M RTVSASSYMV----ADRLIAALGRSGVGDADLLASFRGVLGLVMG-----
MUL_3622|M.ulcerans_Agy99 RTVWASSYMV----ADRLIAALGRSGVGDADLLASFRGVLGLVMG-----
Mb1388c|M.bovis_AF2122/97 AALSPKTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLD
Rv1353c|M.tuberculosis_H37Rv AALSPKTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLD
Mflv_2560|M.gilvum_PYR-GCK PPLGPGTAAK----YDHELRAFDGLGLSDLDMDSALTYVLGFVTS-----
TH_0654|M.thermoresistible__bu FAAGQSRVLD--EILARFAAAAAAAGLEGSRAVLAARTIVHYVLG-----
MAV_5055|M.avium_104 PLEGPFATRLG----NNVLTLLQHNKIDEADAANLLVSAFSLTLG-----
Mvan_1315|M.vanbaalenii_PYR-1 PPADPGQLAW----LDAGLAALSGTGLSERDKLAAVMALLHFVRG-----
MAB_4687|M.abscessus_ATCC_1997 IPVGPNVFMIR----EHTLTLCLQAGFSPAEAIRIYMTLGRYVLG-----
MSMEG_0442|M.smegmatis_MC2_155 AVNSTQAFRMY----NALAVTLGRAGFSAADSLRIITLIDNYVLG-----
. . .
MMAR_3679|M.marinum_M ----------SAQAELAGPLAGTGREKEQVAVAARIGGLAGAEHP-----
MUL_3622|M.ulcerans_Agy99 ----------SAQAELAGPLAGTGREKEQVAVAARIGGLAGAEHP-----
Mb1388c|M.bovis_AF2122/97 RLSRKSQSAGSGPSAIEHPVAIDPATTPLLAHATGRGHRIGAPDETNFEY
Rv1353c|M.tuberculosis_H37Rv RLSRKSQSAGSGPSAIEHPVAIDPATTPLLAHATGRGHRIGAPDETNFEY
Mflv_2560|M.gilvum_PYR-GCK ----------VARIADDAREARRDSGVSDQAWWDRAGPLLAEVFDDE---
TH_0654|M.thermoresistible__bu ---------------------FTGDEQSRLQWDAAG--------------
MAV_5055|M.avium_104 ----------------CALYRTSRSGRTASSRLSQVGDEAPAVRR-----
Mvan_1315|M.vanbaalenii_PYR-1 --------------ASALDIEAADHHDTAPDYPALLRRLVTGERFP----
MAB_4687|M.abscessus_ATCC_1997 -----------------FANQIGAEHRASEADIAMLTRLVENIDLAS---
MSMEG_0442|M.smegmatis_MC2_155 ----------------------SALDLAAPDEPWESGTEVGP--------
MMAR_3679|M.marinum_M -------HIAALAQASQRSTPAADFER--ALDILLAGIESFERRRDRR--
MUL_3622|M.ulcerans_Agy99 -------HIAALAQASQRSTPAADFER--ALDILLAGIESFERRRDRR--
Mb1388c|M.bovis_AF2122/97 GLECILDHAGRLIEQSSKAAGEVAVRR--PTATADAPTPGARAKAVAR--
Rv1353c|M.tuberculosis_H37Rv GLECILDHAGRLIEQSSKAAGEVAVRR--PTATADAPTPGARAKAVAR--
Mflv_2560|M.gilvum_PYR-GCK -KFPLAARIGAAAGQAFGSAYDADHAYRFGLARVLDGLEPVINRTAR---
TH_0654|M.thermoresistible__bu ---------AEVAEPPADDNPSARFAF--GLNLLINGIAAEIDAAARKSE
MAV_5055|M.avium_104 ----------LRGRLTVASADDTVFRD--ALTRLIAGYVTTAAKTGGRRR
Mvan_1315|M.vanbaalenii_PYR-1 ------ALAAALQAEAFDADGDRLADFRSGLDQFLDGIDSRVRRSR----
MAB_4687|M.abscessus_ATCC_1997 --------YPSTLATAGVTLVPLDEEFDFGLGLIVAGLEGLRHGE-----
MSMEG_0442|M.smegmatis_MC2_155 -------ELAAALATGAPKPARADDAFEFGLAVLLRGLTNP---------