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MARKAQGEDKAPRGRGRPPGGGNTAQQAQEQLLDAAERLFIARGYAASTMEAIAREAGYSRAVVYRHFRN RDDLMDALVVRATMNEITNMIGRLMALKSLAEIIPESLVIVSVEVGANPLLRVLADRDDRGTVASLIVDA PNLIDLLTAMYAGVFSTRMAEVRQGVRPEDAARYVLSVALSLLLGLIPGTDDPEQVRRYVRVFVLPTLLA DPPQPEAVFI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0530 | - | - | 100% (220) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2043 | - | 2e-12 | 27.16% (162) | putative transcriptional regulator, TetR |
| M. abscessus ATCC 19977 | MAB_2606c | - | 4e-12 | 27.32% (194) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2534 | - | 5e-09 | 31.40% (172) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0366 | - | 2e-52 | 49.55% (222) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1255c | - | 2e-11 | 31.35% (185) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_02568 | - | 8e-07 | 27.72% (101) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_4418 | - | 2e-43 | 44.71% (208) | transcriptional regulatory protein |
| M. avium 104 | MAV_5275 | - | 3e-11 | 28.57% (126) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0962 | - | 4e-10 | 26.80% (194) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_2255 | - | 4e-10 | 25.51% (196) | TetR-family protein transcriptional regulator |
| M. ulcerans Agy99 | MUL_4487 | - | 1e-09 | 29.95% (197) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0369 | - | 2e-41 | 45.21% (188) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_0530|M.abscessus_ATCC_1997 ---------MARKAQGEDKAPRGRGRPPGGGNTAQQAQEQLLDAAERLFI
MMAR_4418|M.marinum_M --------------------MRRRGRPAGGGNTPEQARRLLVQTAERCFA
Mflv_0366|M.gilvum_PYR-GCK MAEADSEPFAPSASGRSTSPARRRGRPVGGGNTSDQARTVLMDAAERSIL
Mvan_0369|M.vanbaalenii_PYR-1 -----------------------------------------MDAAERSIL
Rv1255c|M.tuberculosis_H37Rv ----------------------MAGTDWLSARRTELAADRILDAAERLFT
MUL_4487|M.ulcerans_Agy99 ----------------------MGRTDWLAAHRSEVAADRILDAAERLYT
MSMEG_0962|M.smegmatis_MC2_155 -----------------------------MP-GPDAASRAILDAALVEFE
TH_2255|M.thermoresistible__bu -----------------------------MPERPDPARQAILDAAVVEFE
MAV_5275|M.avium_104 ------------------MEPSRRWGDDRAILDDEEARRRILEAAGRCIV
Mb2534|M.bovis_AF2122/97 -----------MTASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFA
MLBr_02568|M.leprae_Br4923 ------------------------MAGGAKRIPRAVREQQMLDAAVQMFS
: :*
MAB_0530|M.abscessus_ATCC_1997 ARGYAASTMEAIAREAGYSRAVVYRHFRNRDDLMDALVVRATMNEITNMI
MMAR_4418|M.marinum_M ENG-LDITMAEVAKRAGVSRAVLYRHFGGRDELVVAVAVQVMDRYVARVV
Mflv_0366|M.gilvum_PYR-GCK RRGFQASTMELVAREAGYSRAAIYRHFPSRRLLLEALVERKTRRHQTEIS
Mvan_0369|M.vanbaalenii_PYR-1 QRGFQASTMELIAREAGYSRAAMYRQFPSRQHLLEALVARKTRRHQIEIV
Rv1255c|M.tuberculosis_H37Rv QRDPASIGMNEIAKAAGCSRATLYRYFDSREALRTAYVHRETRRLGREIM
MUL_4487|M.ulcerans_Agy99 EHDPASIGMNEIARAAGCSRATLYRYFESREALRTAYVHRETLRLGREIM
MSMEG_0962|M.smegmatis_MC2_155 RYGFRRVALDDVARRAGVSRTTIYRRFANRDDLVGAVIERENVSLFADIA
TH_2255|M.thermoresistible__bu QHGFRKVALEDVARRAGVSRTTIYRRFTNRDELVAAVVDRENAALFADIA
MAV_5275|M.avium_104 RRGNTQFRMGEVADEAGVSRSTVYRYFPGRDDVLLGLMLRRVDHALAESV
Mb2534|M.bovis_AF2122/97 ERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVSARLLAGAR
MLBr_02568|M.leprae_Br4923 VNGYHKTSMDAIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRFIAMVR
. : :. * * . :* : .: :
MAB_0530|M.abscessus_ATCC_1997 GRLMALKSLAEIIPESLVIVSVEVGANPLLRVLADRDDRGTVASLIVDAP
MMAR_4418|M.marinum_M DDLIPTDDVAALITESLVFVTTVVSRDPLLELLSMGAEHG-VASLLANSP
Mflv_0366|M.gilvum_PYR-GCK ARLTENASLADLLTEGLVIVATELIHDPLLRTLSEQTDEGTVAHLVAGAA
Mvan_0369|M.vanbaalenii_PYR-1 SRMPENADLAEILVEGLVIVATELVHDPLLQTLSEQTDEGTVAHLVAGAA
Rv1255c|M.tuberculosis_H37Rv VKIADVVEPAERLLVSITTTLRMVRDNPALAAWFTTTRPPIGGEMAGRSE
MUL_4487|M.ulcerans_Agy99 QQIGDIDDPRDQLITSITATLRMVRQRPALAAWFASTRPPIGGELAGQSE
MSMEG_0962|M.smegmatis_MC2_155 AELKDAKPQSNIYVEAFTLSILRFRRHRVLNQMMKDEPALVLELAHRHYG
TH_2255|M.thermoresistible__bu AELKHSGPQGDYYVEAFTLAILKFRRHRVLHRMITDEPGFILHLAQQHWG
MAV_5275|M.avium_104 RSLPAPEDPVRSVPQMVLARVESVDGNPLNEALFAAESTAMASALQKGSE
Mb2534|M.bovis_AF2122/97 DVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVR
MLBr_02568|M.leprae_Br4923 ADIDFTQSPKDLLRNTIVSFLRYIDAN-RASWIVMYIQAMSLPAFAQTVR
.
MAB_0530|M.abscessus_ATCC_1997 NLIDLLTAMYAGVFS-TRMAEVRQGVRPEDAARYVLSVALSLLLGLIPGT
MMAR_4418|M.marinum_M VLCGKVAGLYEQVFV-LFRDRLRVGLEPGDVGRYILGVALSLLMNVIPGS
Mflv_0366|M.gilvum_PYR-GCK RIPEQVEQLIAATDGGESEKIFRPGVEAGDVGQFLITAALTMLLGVIPGI
Mvan_0369|M.vanbaalenii_PYR-1 RLPELVEQLFEAMDDGEAGPTFRPGLRADDVGQFLVTTSLTMLLGVIPGI
Rv1255c|M.tuberculosis_H37Rv VIAALAAAFLNSLGPDDPTTVERR-------ARWVVRMLTSLLM--FPGR
MUL_4487|M.ulcerans_Agy99 VIAGLAAAFLQSLGPEAPAAVERR-------ARWTVRVIVSLLM--FPGQ
MSMEG_0962|M.smegmatis_MC2_155 AAIERMAAALRVIFPEGFADRIGEAAVNDLADTILRYALMALLIPSVEPL
TH_2255|M.thermoresistible__bu AAVERMAEALRVIFPAGFAERIGEAAVIEFADTILRYAAMALLLPSVQPL
MAV_5275|M.avium_104 PLVELLLRHYGPLLERWKAAGLLYPDVDFRSVVQWLHTATLFLLAPSWRY
Mb2534|M.bovis_AF2122/97 KAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSK
MLBr_02568|M.leprae_Br4923 EARDQITELVAGLMR-VGTRSSRPDHEYEIMAGALVGAGEAMATRLTTGD
MAB_0530|M.abscessus_ATCC_1997 DDPEQVRRYVRVFVLPTLLADPPQPEAVFI----
MMAR_4418|M.marinum_M DDPATVRRYVRTFVLPAIVASPPDAVSVFV----
Mflv_0366|M.gilvum_PYR-GCK EDPETARRYVRTFVLPAILADPPAPQQVFRPR--
Mvan_0369|M.vanbaalenii_PYR-1 ADSETARRYVQTFVLPAILADPPAPREVFGS---
Rv1255c|M.tuberculosis_H37Rv DE-ADERAMIAEFVVPIVTPASAAARKAGHPGPE
MUL_4487|M.ulcerans_Agy99 DE-ADERAMLEEFVAPVVTPFPTRR---------
MSMEG_0962|M.smegmatis_MC2_155 ETADDIRSFATRHFLPSLPVSLRVVPA-------
TH_2255|M.thermoresistible__bu DTADDIRAFATRHFLPSLPAALHTGSA-------
MAV_5275|M.avium_104 RPHADKRRFVEQFVVRALVPQIRQ----------
Mb2534|M.bovis_AF2122/97 PARTVRARAVLRAMTVAALSAADRCL--------
MLBr_02568|M.leprae_Br4923 IAVDEAAELMINLFWHGLKGAPADRDFGPSIVAG
.