For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_2782 (-)

annotation: acyl-CoA dehydrogenase domain protein
coordinates: 1542028 - 1543188
length: 387

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2782--100% (387)acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)TH_4603-1e-7440.81% (370) PUTATIVE acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)TH_3846-9e-7440.16% (376) PUTATIVE acyl-CoA dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2528cfadE191e-17779.53% (386) acyl-CoA dehydrogenase
M. gilvum PYR-GCKMflv_2554-0.087.82% (386) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37RvRv2500cfadE191e-17779.53% (386) acyl-CoA dehydrogenase
M. leprae Br4923MLBr_00737fadE255e-7240.43% (376) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977MAB_4538c-1e-16275.59% (381) putative acyl-CoA dehydrogenase FadE
M. marinum MMMAR_3847fadE190.081.65% (387) acyl-CoA dehydrogenase FadE19
M. avium 104MAV_1672-0.083.46% (387) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155MSMEG_4715-0.088.11% (387) acyl-CoA dehydrogenase
M. ulcerans Agy99MUL_3778fadE190.081.14% (387) acyl-CoA dehydrogenase FadE19
M. vanbaalenii PYR-1Mvan_4089-0.089.64% (386) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb2528c|M.bovis_AF2122/97           --MTTTTTTISGGILPKEYQDLRDTVADFARTVVAPVSAKHDAEHSFPYE
Rv2500c|M.tuberculosis_H37Rv        --MTTTTTTISGGILPKEYQDLRDTVADFARTVVAPVSAKHDAEHSFPYE
MMAR_3847|M.marinum_M               -----MTTAISAGTLPKEYQDLRDTVADFARSVVAPVSAKHDEEHSFPYE
MUL_3778|M.ulcerans_Agy99           -----MTTAISAGTLPKEYQDLRDTVADFARSVVAPVSAKHDEEHSFPYE
MAV_1672|M.avium_104                -----MTTSITAGTLPKEYQDLRDTVAEFARTVVAPVSAKHDEEHSFPYE
Mflv_2554|M.gilvum_PYR-GCK          -----MSDFLSTGTLPDHYAQLAKTVRDFAQSVVAPVAAKHDEEHSFPYE
MSMEG_4715|M.smegmatis_MC2_155      -----MTDFLSTGSLPDDYEQLAKTVRDFAQSVVAPVAAKHDEEHSFPYE
Mvan_4089|M.vanbaalenii_PYR-1       -----MSNNLATGILPDHYEQLAKTVRDFAQSVVAPVAAKHDEEHSFPYE
TH_2782|M.thermoresistible__bu      -----MPDYLTTGNLPDHYAELAGTVRDFAQSVVAPVAAKHDQERSFPYE
MAB_4538c|M.abscessus_ATCC_199      -------MTFSTAELPDEYESLRKTVEEFAHSVVAPAAAHHDATKTFPYA
MLBr_00737|M.leprae_Br4923          MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE
                                             :    **..: .*  *:  :*.. :** :*. *    **  

Mb2528c|M.bovis_AF2122/97           IVAKMGEMGLFGLPFPEEYGGMGGDYFALSLVLEELGKVDQSVAITLEAA
Rv2500c|M.tuberculosis_H37Rv        IVAKMGEMGLFGLPFPEEYGGMGGDYFALSLVLEELGKVDQSVAITLEAA
MMAR_3847|M.marinum_M               VVAKMGEMGLFGLPFPEEYGGMGGDYFALALALEELGKVDQSVAITLEAG
MUL_3778|M.ulcerans_Agy99           VVAKMGEMGLFGLPFPEEYGGMGGDYFALALALEELGKVNQSVAITLEAG
MAV_1672|M.avium_104                VVAKMGEMGLFGLPFPEEYGGMGGDYFALSLALEELGKVDQSVAITLEAG
Mflv_2554|M.gilvum_PYR-GCK          VVSGMADMGLFGLPFPEEYGGMGGDYFALCLALEELGKVDQSVAITLEAG
MSMEG_4715|M.smegmatis_MC2_155      VVAGMADMGLFGLPFPEEYGGMGGDYFALCLALEELGRVDQSVAITLEAG
Mvan_4089|M.vanbaalenii_PYR-1       VVAGMADMGLFGLPFPEEYGGMGGDYFALCLALEELGKVDQSVAITLEAG
TH_2782|M.thermoresistible__bu      VVAAMGEMGLFGLPFPEEYGGMGGDYFALCLALEELGKVDQSVAITLEAG
MAB_4538c|M.abscessus_ATCC_199      VVAQMGEMGLFGLPFPEEYGGMGGDYFALCLTLEELARADQSVAITLEAA
MLBr_00737|M.leprae_Br4923          ALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASL-IPAV
                                     :: :   *: .: .****** *.* .* .:.:**:.:.: *.:: : * 

Mb2528c|M.bovis_AF2122/97           VGLGAMPIYRFGTEEQKQKWLPDLTSGRALAGFGLTEPGAGSD-AGSTRT
Rv2500c|M.tuberculosis_H37Rv        VGLGAMPIYRFGTEEQKQKWLPDLTSGRALAGFGLTEPGAGSD-AGSTRT
MMAR_3847|M.marinum_M               VGLGAMPIYRFGNEEQKSKWLPDLLAGRALAGFGLTEPGAGSD-AGSTRT
MUL_3778|M.ulcerans_Agy99           VGLGAMPIYRFGNEEQKSKWLPDLLAGRALAGFGLTEPGAGSD-AGSTRT
MAV_1672|M.avium_104                VSLGAMPIYRFGNEEQKRKWLPDLTAGRALAGFGLTEPGAGSD-AGATRT
Mflv_2554|M.gilvum_PYR-GCK          VSLGAMPVYRFGNESQKQEWLPLLASGKALGAFGLTEAGGGSD-AGATKT
MSMEG_4715|M.smegmatis_MC2_155      VSLGAMPVYRFGNDAQKQEWLPLLASGKALGAFGLTEAGGGSD-AGATKT
Mvan_4089|M.vanbaalenii_PYR-1       VSLGAMPVYRFGTEAQKQEWLPLLASGKALGAFGLTEAGGGSD-AGATKT
TH_2782|M.thermoresistible__bu      VSLGAMPIYRFGTEEQKQRWLPELAAGKALGAFGLTEPGGGSD-AGATRT
MAB_4538c|M.abscessus_ATCC_199      VSLGAMPVYRYGSEEQKQRWLPELASGKSLAAFGLTEPGGGTDIPGSIRT
MLBr_00737|M.leprae_Br4923          NKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSD-AASMRT
                                      **:* :   *.:  * . ** * :  ::..:.*:*  .*:* ..: :*

Mb2528c|M.bovis_AF2122/97           TARLEGDEWIINGSKQFITNSGTDITSLVTVTAVTGTTGTAADAKKEIST
Rv2500c|M.tuberculosis_H37Rv        TARLEGDEWIINGSKQFITNSGTDITSLVTVTAVTGTTGTAADAKKEIST
MMAR_3847|M.marinum_M               TARLDGGEWVVNGSKQFITNSGTDITSLVTITAVTG---SIADGKKEIST
MUL_3778|M.ulcerans_Agy99           TARLDGGEWVVNGSKQFITNSGTDITSLVTITAVTG---SIADGKKEIST
MAV_1672|M.avium_104                TARLEDGEWVINGSKQFITNSGTDITSLVTVTAVTG---TVGADKKEIST
Mflv_2554|M.gilvum_PYR-GCK          TAKSDGASWVINGTKQFITNSGTDITKLVTVTAVTG---EN-NGKKEISS
MSMEG_4715|M.smegmatis_MC2_155      TARLDDGHWVINGSKQFITNSGTDITRLVTVTAVTG---EKPDGRKEISS
Mvan_4089|M.vanbaalenii_PYR-1       TARLDDGHWVINGSKQFITNSGTDITKLVTVTAVTG---ET-DGKKEISS
TH_2782|M.thermoresistible__bu      TARLDDGHWVINGSKQFITNSGTDITKLVTVTAVTG---EV-AGKKEISA
MAB_4538c|M.abscessus_ATCC_199      RAVEDNGSWVINGAKAFITNSGTDITAVVGVAAVTG---RSADGSPEISV
MLBr_00737|M.leprae_Br4923          RAKADGDDWILNGFKCWITNGGK--STWYTVMAVTD----PDKGANGISA
                                     *  :.  *::** * :***.*.  :    : ***.           ** 

Mb2528c|M.bovis_AF2122/97           IIVPSGTPGFTVEPVYNKVGWNASDTHPLTFADARVPRENLLGARGSGYA
Rv2500c|M.tuberculosis_H37Rv        IIVPSGTPGFTVEPVYNKVGWNASDTHPLTFADARVPRENLLGARGSGYA
MMAR_3847|M.marinum_M               IIVPSGTPGFIVEPVYNKVGWNASDTHPLSFDDARVPEENLLGIRGKGYA
MUL_3778|M.ulcerans_Agy99           IIVPSGTPGFIVEPVYNKVGWNASDTHPLSFDDARVPEENLLGIRGKGYA
MAV_1672|M.avium_104                IIVPSGTPGFTVEPVYSKVGWNASDTHPLSFSDARVPEENLLGARGTGYA
Mflv_2554|M.gilvum_PYR-GCK          ILVPVPTEGFTAEPAYNKVGWNASDTHPLSFDDVRVPQENLLGERGRGYA
MSMEG_4715|M.smegmatis_MC2_155      ILVPVPTEGFTAEPAYNKVGWNASDTHPLSFDDVRVPEENLLGERGRGYA
Mvan_4089|M.vanbaalenii_PYR-1       ILVPVPTPGFTAEPAYNKVGWNASDTHPLSFDDVRVPQENLLGERGRGYA
TH_2782|M.thermoresistible__bu      IIVPVPTDGFTVEPAYHKVGWNASDTHPLSFDDVRVPEENLLGERGRGYA
MAB_4538c|M.abscessus_ATCC_199      IHVPSGTPGFTVEPGYDKVGWHASDTHPLSFDDVRVPYENLLGERGRGYA
MLBr_00737|M.leprae_Br4923          FIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFK
                                    : *     **   *   *:* :.* *  * * . *:* :.::*  * *: 

Mb2528c|M.bovis_AF2122/97           NFLSILDEGRIAIAALATGAAQGCVDESVKYANQRQSFGQPIGAYQAIGF
Rv2500c|M.tuberculosis_H37Rv        NFLSILDEGRIAIAALATGAAQGCVDESVKYANQRQSFGQPIGAYQAIGF
MMAR_3847|M.marinum_M               NFLSILDEGRIAIAALATGVAQGCVDESVKYAKERQSFGQPIGSYQAISF
MUL_3778|M.ulcerans_Agy99           NFLSILDEGRIAIAALATGVAQGCVDESVKYAKERQSFGQPIGSYQAISF
MAV_1672|M.avium_104                NFLSILDEGRIAIAALATGAAQGCVDESVKYAKERQSFGQPIGSYQAISF
Mflv_2554|M.gilvum_PYR-GCK          NFLRILDEGRIAIAALSVGAAQGCVDESVKYAKERQAFGAAIGTYQAIAF
MSMEG_4715|M.smegmatis_MC2_155      NFLRILDEGRIAIAALSVGAAQGCVDESVKYAKERQAFGAAIGTYQAIAF
Mvan_4089|M.vanbaalenii_PYR-1       GFLRILDEGRIAIAALSVGAAQGCVDESVKYAKERHAFGRAIGTNQAIAF
TH_2782|M.thermoresistible__bu      NFLRILDEGRIAIAALSVGAAQGCVDESVKYAKEREAFGRPIGANQAIAF
MAB_4538c|M.abscessus_ATCC_199      GFLRILDEGRIAIAAVATGAAQGCVDESLRYARSRPAFGSAIIDYQSVSF
MLBr_00737|M.leprae_Br4923          TALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQF
                                      *  **. * :*.* :.* ***.:* :: *:..*  ** .*   *:: *

Mb2528c|M.bovis_AF2122/97           KIARMEARAHVARTAYYDAAAKMLAGKP-FKKEAAIAKMISSEAAMDNSR
Rv2500c|M.tuberculosis_H37Rv        KIARMEARAHVARTAYYDAAAKMLAGKP-FKKEAAIAKMISSEAAMDNSR
MMAR_3847|M.marinum_M               KIARMEARAHVARTAYYEAAAKMLAGKP-FKKEAAIAKMISSEAAMDNAR
MUL_3778|M.ulcerans_Agy99           KIARMEARAHVARTAYYEAAAKMLAGKP-FKKEAAIAKMISSEAAMDNAR
MAV_1672|M.avium_104                KIARMEARAHVARTAYYDAAAKMLAGKP-FKKEAAIAKMIASEAAMDNAR
Mflv_2554|M.gilvum_PYR-GCK          KIARMEARAHTARAAYYDAAALMLSGKP-FKKAASVAKMVASEAAMDNAR
MSMEG_4715|M.smegmatis_MC2_155      KIARMEARAHAARTAYYDAAALMLAGKP-FKKAASVAKLVASEAAMDNAR
Mvan_4089|M.vanbaalenii_PYR-1       KIARMEARAHAARAAYYDAAALMLAGKP-FKKAAAVAKLVSSEAAMDNAR
TH_2782|M.thermoresistible__bu      KIARMEARAHTARTAYYDAAALMLAGKP-FKKQAAIAKMVASEAAMDNAR
MAB_4538c|M.abscessus_ATCC_199      KIARMQARAHTARLAYYHAAALLLAGKP-FKTEASIAKLIASEAAMDNAR
MLBr_00737|M.leprae_Br4923          MLADMAMKVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEVTT
                                     :* *  :...**   * ***    *:* :   :: :* .:*: **: : 

Mb2528c|M.bovis_AF2122/97           DATQIHGGYGFMNEYPVARHYRDSKVLEIGEGTTEVQLMLIARSLGLQ
Rv2500c|M.tuberculosis_H37Rv        DATQIHGGYGFMNEYPVARHYRDSKVLEIGEGTTEVQLMLIARSLGLQ
MMAR_3847|M.marinum_M               DATQVHGGYGFMNEYPVARHYRDSKILEIGEGTTEVQLMLIARSLGLS
MUL_3778|M.ulcerans_Agy99           DAAQVHGGYGFMNEYPVARHYRDSKILEIGEGTTEVQLMLIARSLGLS
MAV_1672|M.avium_104                DATQIHGGYGFMNEYPVARHYRDSKILEIGEGTTEVQLMLIARSLGLS
Mflv_2554|M.gilvum_PYR-GCK          DATQIFGGYGFMNEYSVARHYRDSKILEIGEGTTEVQLMLIGRELGL-
MSMEG_4715|M.smegmatis_MC2_155      DATQIFGGYGFMNEYSVARHYRDSKILEIGEGTTEVQLMLIGRELGL-
Mvan_4089|M.vanbaalenii_PYR-1       DATQIFGGYGFMNEYPVARHYRDSKILEIGEGTTEVQLMLIGRELGL-
TH_2782|M.thermoresistible__bu      DATQIFGGYGFINEFPVARHYRDSKILEIGEGTTEVQLMLIGRELGL-
MAB_4538c|M.abscessus_ATCC_199      DATQIFGGAGFMNESPVARQYRDSKILEIGEGTSEVQLMLIARALTG-
MLBr_00737|M.leprae_Br4923          DAVQLFGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR-
                                    **.*:.** *: .: .* *  **:*: :* ***.::* :::.* *