For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MPPEPRRSDATRAAILEAAQEHFASVGYEKATIRAIAGTAGIDPSLVMRYYGNKGKLFAAAANFDLCLPE LSAVSHEELGTVIVQHFLERWEVDDTMVALLRAAVSNEEARLRMVEIFTDQSLPAFEELLTDHAAERAAL IGGQMIGFAVCRYILRLSPVIEMTHQDIVNWMAPIVQQYIDTPAP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2885 | - | - | 100% (185) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2351c | - | 4e-16 | 30.77% (195) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4776c | - | 1e-13 | 30.43% (161) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1711c | - | 7e-19 | 31.09% (193) | hypothetical protein Mb1711c |
| M. gilvum PYR-GCK | Mflv_0253 | - | 1e-21 | 33.51% (188) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1685c | - | 7e-19 | 31.09% (193) | hypothetical protein Rv1685c |
| M. leprae Br4923 | MLBr_02568 | - | 4e-06 | 28.24% (131) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_0204 | - | 1e-41 | 41.11% (180) | hypothetical protein MMAR_0204 |
| M. avium 104 | MAV_3088 | - | 3e-18 | 31.28% (195) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1700 | - | 1e-44 | 50.00% (178) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3542 | - | 2e-21 | 34.27% (178) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_4899 | - | 2e-42 | 40.54% (185) | hypothetical protein MUL_4899 |
| M. vanbaalenii PYR-1 | Mvan_0641 | - | 7e-22 | 33.51% (185) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_2885|M.abscessus_ATCC_1997 ---------MPPEPRRSDATRAAILEAAQEHFASVGYEKATIRAIAGTAG
MSMEG_1700|M.smegmatis_MC2_155 ---------MR---RSAAETKSVILAAARERFAADGYERATIRSIAADAS
MMAR_0204|M.marinum_M -----------MKTRDATATRSAILDAAQSQFGENGFERTTIRSVAKAAG
MUL_4899|M.ulcerans_Agy99 ---------MPVKTRDATATRSAILDAAQSQFGENGFERTTIRSVAKAAG
Mb1711c|M.bovis_AF2122/97 MAAPDNSRRRPGRPAGSSDTRERILSSARELFAHNGIDRTSIRAVAAKAG
Rv1685c|M.tuberculosis_H37Rv MAAPDNSRRRPGRPAGSSDTRERILSSARELFAHNGIDRTSIRAVAAKAG
MAV_3088|M.avium_104 MTTTGTTRRRRGRPAGSSGSRERILASARELFARNGIRNTSIRAVAAAAG
Mflv_0253|M.gilvum_PYR-GCK MPPPAQTGRRRGRRKGDPVSRETVLAAAKGRFARDGFEKTTLRAIAEDAG
Mvan_0641|M.vanbaalenii_PYR-1 MPRPGETARRRGRRQGEPVSKEAVLAAAKTRFARDGYEKTTLRAIADDAR
TH_3542|M.thermoresistible__bu -----------------------VLAAAKRRFAQDGYEKTTLRAIARDAH
MLBr_02568|M.leprae_Br4923 -------MAGGAKRIPRAVREQQMLDAAVQMFSVNGYHKTSMDAIAAEAQ
:* :* *. * .::: ::* *
MAB_2885|M.abscessus_ATCC_1997 IDPSLVMRYYGNKGKLFAAAANFDLC----LPELSAVS---HEELGTVIV
MSMEG_1700|M.smegmatis_MC2_155 IDPSMVMRYFGNKERLFAAAAEFDLE----LPDLALVP---REEIGATLA
MMAR_0204|M.marinum_M VDPALVMHYFGSKAGLFTAATRFDIK----FPDLSGIP---MDRIADALL
MUL_4899|M.ulcerans_Agy99 VDPALVMHYFGSKAGLFTAATRFDIK----FPDLSGIP---MDRIADALL
Mb1711c|M.bovis_AF2122/97 VDAALVHHYFGTKQQLFAAAIHIPIDPMVIIGPIREAP---VEELGYKLP
Rv1685c|M.tuberculosis_H37Rv VDAALVHHYFGTKQQLFAAAIHIPIDPMVIIGPIREAP---VEELGYKLP
MAV_3088|M.avium_104 VDSALVHHYFGTKEKLFAAAVQIPIDPMQVIGPLREVP---VDDLGYALP
Mflv_0253|M.gilvum_PYR-GCK VDASMVLYLFGSKEALFRESLRLILDPGVLIEALSGGE----ADIGTRMV
Mvan_0641|M.vanbaalenii_PYR-1 VDASMVLYLFGSKEQLFREALRLILDPEVLVAALAGVEGD-SSDVGTRMV
TH_3542|M.thermoresistible__bu VDASMVLYLFGSKAELFRESLELILDPEMLVAAMTGDD----GDVGTRMV
MLBr_02568|M.leprae_Br4923 ISKPMLYLYYGSKEDLFGACLNREMSRFIAMVRADIDFTQSPKDLLRNTI
:. .:: :*.* ** . . : . :
MAB_2885|M.abscessus_ATCC_1997 QHFLERWE-VDD--TMVALLRAAVSNEEARLRMVEIFTDQSLPAFEELL-
MSMEG_1700|M.smegmatis_MC2_155 GHFLERWE-RDE--ALLILLRAGVTNEAVAERMRTIFAAQLAPVIAKLTG
MMAR_0204|M.marinum_M PNFLRVWG-PRG--AFLPLLRAAASNRDAADALVEVFVDRVGPALSAIV-
MUL_4899|M.ulcerans_Agy99 PNFLRVWG-PRG--AFLPLLRAAATNRDAADALVEVFVDRVGPALSAIV-
Mb1711c|M.bovis_AF2122/97 SLLLPIWD-SELGAGLIATLRSLISGSDVGLARSFLEEVVTVELGSRVDN
Rv1685c|M.tuberculosis_H37Rv SLLLPIWD-SELGAGLIATLRSLISGSDVGLARSFLEEVVTVELGSRVDN
MAV_3088|M.avium_104 SMLLPLWD-SEVGAAFIATLRSILAGEEISLFRTFIQDVIGVEVGPRVDN
Mflv_0253|M.gilvum_PYR-GCK RAYLGVWESPESAESMRTMLASATSNPDAREAFRGFIQDYVLAAVVGTLG
Mvan_0641|M.vanbaalenii_PYR-1 RTYLGIWEAADSAASMRAMLASATSNPDAHEAFRSFMQDYVLTAVSGVLG
TH_3542|M.thermoresistible__bu RVYLQIWESPDTGPTIRAMLQSATSNTDAREAFRSFLREYLLTAVSGVLG
MLBr_02568|M.leprae_Br4923 VSFLRYIDANRASWIVMYIQAMSLPAFAQTVREARDQITELVAGLMRVGT
* . .
MAB_2885|M.abscessus_ATCC_1997 -TDHAAERAALIGGQMIGFAVCRYILRLSPVIEMTHQDIVNWMAPIVQQY
MSMEG_1700|M.smegmatis_MC2_155 GAPDAPVRASLAASQVLGMALCRYVLAFPPLVDMSRDGVVAWIGPTLQRY
MMAR_0204|M.marinum_M -PDRGPERAALVAAQMVGVATARYVIGLPPLLHMDDEELIRWLRPVIVHY
MUL_4899|M.ulcerans_Agy99 -PDRGPERAALVAAQMVGVATARYVIGLPPLLHMDDEELIRWLRPVIVHY
Mb1711c|M.bovis_AF2122/97 PPGTGKIRTQFVASQLMGVVMARYIVRIEPFASLPAEQIVQTIAPNLQRY
Rv1685c|M.tuberculosis_H37Rv PPGTGKIRTQFVASQLMGVVMARYIVRIEPFASLPAEQIVQTIAPNLQRY
MAV_3088|M.avium_104 PAGSGVIRIQFVASQLVGVVMARYILELEPFASLPPEQIAATIAPNLQRY
Mflv_0253|M.gilvum_PYR-GCK GDDRARLRAMLAASSLVGTAMMRYLMEIPPLSELATEDVIRLVAPTVTRY
Mvan_0641|M.vanbaalenii_PYR-1 GGEQARLRAMLAASSLVGTAMLRYVMRVAPLAELPTEDVVRLVAPTVTRY
TH_3542|M.thermoresistible__bu GGEQARLRAELAATGLVGTAMLRYIMRVPPLAELSTEEVVRMLAPTVNRY
MLBr_02568|M.leprae_Br4923 RSSRPDHEYEIMAGALVGAGEA--MATRLTTGDIAVDEAAELMINLFWHG
. : . ::* : . : : : . :
MAB_2885|M.abscessus_ATCC_1997 IDTPAP------------
MSMEG_1700|M.smegmatis_MC2_155 LVG---------------
MMAR_0204|M.marinum_M LTDPAP------------
MUL_4899|M.ulcerans_Agy99 LTDPAP------------
Mb1711c|M.bovis_AF2122/97 LTGELPDDLAP-------
Rv1685c|M.tuberculosis_H37Rv LTGELPDDLAP-------
MAV_3088|M.avium_104 LTGDLPDGLAP-------
Mflv_0253|M.gilvum_PYR-GCK LTAPADELGLPG------
Mvan_0641|M.vanbaalenii_PYR-1 LTADARELGLPD------
TH_3542|M.thermoresistible__bu LTADADELGLPSSLTAGS
MLBr_02568|M.leprae_Br4923 LKGAPADRDFGPSIVAG-
: