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VSNGGLKGSVAAPRADVGTRRRDDALMSAIRDATYAELQDHGYAGVTFEGVARRAKTSKPVLYRRYRSRA HMVADALPTLRYPPTRLASATSLREDVLALLGALLRELHRIGVGNYRCLLAEADDGLADDMTTAIAGWVD QTVLRALADARERGEIGPEDIPLPVATSILALMRHELFFTRKPFGESKLAELFDTVYLPLINLTSRGG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2022 | - | - | 100% (208) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3565 | - | 1e-10 | 30.72% (166) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3151 | - | 4e-08 | 27.59% (203) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1199c | - | 7e-13 | 29.59% (196) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3683 | - | 1e-13 | 28.87% (194) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1167c | - | 7e-13 | 29.59% (196) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_4284 | - | 3e-12 | 31.38% (188) | transcriptional regulatory protein |
| M. avium 104 | MAV_1309 | - | 2e-14 | 31.89% (185) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3834 | - | 9e-12 | 34.69% (147) | putative TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_4110 | - | 2e-08 | 42.03% (69) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_4780 | - | 3e-09 | 46.03% (63) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2727 | - | 4e-13 | 30.16% (189) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1199c|M.bovis_AF2122/97 ----------------------------MTVSAPAKANPYR--RRGEVLE
Rv1167c|M.tuberculosis_H37Rv ----------------------------MTVSAPAKANPYR--RRGEVLE
MMAR_4284|M.marinum_M ----------------------------MAQLSEPMLTPYRSRRRGEVLE
MAV_1309|M.avium_104 MQRTLPAAVVRLLRREAADRNAHGYYQEMPQLTD--RTGSRSRRRGEVLE
Mflv_3683|M.gilvum_PYR-GCK ---------------------------------------MMTRRRGAELD
Mvan_2727|M.vanbaalenii_PYR-1 ----------------------------------------MGRRRGAELD
MAB_2022|M.abscessus_ATCC_1997 -----------------------MSNGGLKGSVAAPRADVGTRRRDDALM
MSMEG_3834|M.smegmatis_MC2_155 --------------------------------------MTAGRPQEARVT
MUL_4780|M.ulcerans_Agy99 ------------------------------------MVADFGRPRDPRID
TH_4110|M.thermoresistible__bu --------------------------VTATDAAATGRAAARGRPRDPALD
: :
Mb1199c|M.bovis_AF2122/97 RALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAV
Rv1167c|M.tuberculosis_H37Rv RALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAV
MMAR_4284|M.marinum_M RALYSATLAELIAVGYGRLTMEGIAARAQTGKAALYRRWASKHDLVQAAL
MAV_1309|M.avium_104 RALYEATLAELTEVGYGGLTMEGIAARAHTGKAALYRRWDTKCELVHAAL
Mflv_3683|M.gilvum_PYR-GCK AAIRSAVLDLLAGHGPEAVTMDAVAVAAGTSKPVLYRRWPDRRALLRDTL
Mvan_2727|M.vanbaalenii_PYR-1 AAIRAAVLELLAEHGPDGVTMDAVAVTAQTSKPVLYRRWPDRRALLRDTL
MAB_2022|M.abscessus_ATCC_1997 SAIRDATYAELQDHGYAGVTFEGVARRAKTSKPVLYRRYRSRAHMVADAL
MSMEG_3834|M.smegmatis_MC2_155 TVILDAVLSELAEHGFGSMTVDGVAKRAGAGKGAIYRRWPSKIEMTAAAM
MUL_4780|M.ulcerans_Agy99 GAVLRATVELLAETGYAGLLVSAIAKRAGTSKPAIYRRWPSKAHLVHEAV
TH_4110|M.thermoresistible__bu SAILDAALEIFVEQGISALSIEQVARRAGVGKPTIYRRWSDKEQLVADAI
.: *. : * : .. :* * ..* .:***: : : ::
Mb1199c|M.bovis_AF2122/97 QY-----ALPPVPEPRADRSARENLLAVFTANCEILAG-KTALPSMEIVS
Rv1167c|M.tuberculosis_H37Rv QY-----ALPPVPEPRADRSARENLLAVFTANCEILAG-KTALPSMEIVS
MMAR_4284|M.marinum_M QY-----AVPPPPEPRPGRSARENLLTVFTAHRDVLAG-KTEFPGLVAIG
MAV_1309|M.avium_104 VF-----ALPPVPELRSGRSARENLLAMFTAQRDLLAG-KTAFPGIEVIQ
Mflv_3683|M.gilvum_PYR-GCK MA-----VASTSFPRPDTGTFRGDLLAVLRAWAQLFTG-DTGPLMRSVIV
Mvan_2727|M.vanbaalenii_PYR-1 LG-----IATSAFPTVDTGGFRGDMLAVLRAWAALFTG-DSAALMRSAIG
MAB_2022|M.abscessus_ATCC_1997 PT-----LRYPPTRLASATSLREDVLALLGALLRELHR-IGVGNYRCLLA
MSMEG_3834|M.smegmatis_MC2_155 RT-----LALPEGAAPDTGSLYGDVLALLADVNRWIGDERMRRLYPDLLA
MUL_4780|M.ulcerans_Agy99 FP-----IDAAT-AVPDTGSPVDDLREMVRRTTAVLSTPAAKAAQPGLIG
TH_4110|M.thermoresistible__bu EHRVSAELAWPTPAEASVSDPYELVRRNISAAARTAADPAFRGLIAAIYG
. : .
Mb1199c|M.bovis_AF2122/97 QLLHEPELRAIFINSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIG
Rv1167c|M.tuberculosis_H37Rv QLLHEPELRAIFINSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIG
MMAR_4284|M.marinum_M QLIHEPELRAIFANSVVHPRLKIIDSVLRAAIREGDLDPDTVTPFTARIG
MAV_1309|M.avium_104 QLLHEPEMRAIFADAVVRPRLKIVESILQSAVQDGDLDPKSITPLTARIG
Mflv_3683|M.gilvum_PYR-GCK AVASDPDLESTFRSDVLGMRKAEMTTLIGRAVERGEVRPDVPVELVRELG
Mvan_2727|M.vanbaalenii_PYR-1 AVTADPELAATFRTDVIGARKQEMDAIITRGVQRGEVRADVPVDLVRELG
MAB_2022|M.abscessus_ATCC_1997 EADDG--LADDMTTAIAGWVDQTVLRALADARERGEIGPEDIPLPVATSI
MSMEG_3834|M.smegmatis_MC2_155 EAQRNPVLAEALMDTVGTPRRARARDILDRAATRGELAPGADSELLVDAM
MUL_4780|M.ulcerans_Agy99 EMAADPTLHSALLVRFGEIFGHGLTTWLDNAAARGQVRADVTAPELAEAI
TH_4110|M.thermoresistible__bu SAVTHPALLRTYWEHYILPRRTAAIALLRRARDLGTVAADADLDVLVDML
: : . * : .
Mb1199c|M.bovis_AF2122/97 PALIHQHVLFTGSPPDREQLTRIIDAMILTTGERRES----
Rv1167c|M.tuberculosis_H37Rv PALIHQHVLFTGSPPDREQLTRIIDAMILTTGERRES----
MMAR_4284|M.marinum_M PALMNQHFILTGTPPNRRELALIVDTVIPPKRTSTCDNCDN
MAV_1309|M.avium_104 SALINQHFLLNGSPPNRRELALIVDTVIPPRGSDRAAD---
Mflv_3683|M.gilvum_PYR-GCK QSVLWHRLLITGDPITDELVTQLVDEVLIPVTRPYYDQ---
Mvan_2727|M.vanbaalenii_PYR-1 QSVLWHRLLISGDPIDDEVVTRLVDEVLIPVTRPYYEV---
MAB_2022|M.abscessus_ATCC_1997 LALMRHELFFTRKPFGESKLAELFDTVYLPLINLTSRGG--
MSMEG_3834|M.smegmatis_MC2_155 GALVFWRLIALFRPVTSEYLDRVARAICAFARTGPV-----
MUL_4780|M.ulcerans_Agy99 AGIVLIGLLTRPGELEPGVGDAWIDRTTTLLLKGIRKGTPQ
TH_4110|M.thermoresistible__bu AGAVTYRVLQ-PEPPSARQLRCYLEVAYRQVGLLP------
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