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QRTLPAAVVRLLRREAADRNAHGYYQEMPQLTDRTGSRSRRRGEVLERALYEATLAELTEVGYGGLTMEG IAARAHTGKAALYRRWDTKCELVHAALVFALPPVPELRSGRSARENLLAMFTAQRDLLAGKTAFPGIEVI QQLLHEPEMRAIFADAVVRPRLKIVESILQSAVQDGDLDPKSITPLTARIGSALINQHFLLNGSPPNRRE LALIVDTVIPPRGSDRAAD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1309 | - | - | 100% (230) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_4754 | - | 5e-14 | 27.45% (204) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_4057 | - | 4e-13 | 29.70% (165) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1199c | - | 8e-68 | 67.38% (187) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3021 | - | 3e-16 | 31.75% (189) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1167c | - | 8e-68 | 67.38% (187) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2022 | - | 3e-14 | 31.89% (185) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4284 | - | 1e-76 | 71.57% (197) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_3129 | - | 2e-18 | 30.05% (183) | putative HTH-type transcriptional regulator |
| M. thermoresistible (build 8) | TH_0688 | - | 6e-12 | 30.60% (183) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_2482 | - | 2e-12 | 28.48% (165) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2727 | - | 1e-16 | 30.60% (183) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
TH_0688|M.thermoresistible__bu ---------------------------MTTNSTSVDKAAGAGRPRDPRID
MUL_2482|M.ulcerans_Agy99 ---------------------------MKADPSSLDKAPGAGRPRDPRID
MAV_1309|M.avium_104 MQRTLPAAVVRLLRREAADRNAHGYYQEMPQLTD--RTGSRSRRRGEVLE
MMAR_4284|M.marinum_M ----------------------------MAQLSEPMLTPYRSRRRGEVLE
Mb1199c|M.bovis_AF2122/97 ----------------------------MTVSAPAKANPYR--RRGEVLE
Rv1167c|M.tuberculosis_H37Rv ----------------------------MTVSAPAKANPYR--RRGEVLE
MSMEG_3129|M.smegmatis_MC2_155 -----------------------------------------MRRTGDQLK
Mvan_2727|M.vanbaalenii_PYR-1 ----------------------------------------MGRRRGAELD
Mflv_3021|M.gilvum_PYR-GCK --------------------------MCVVSDPRSDPPSAPLKSRRTARE
MAB_2022|M.abscessus_ATCC_1997 -----------------------MSNGGLKGSVAAPRADVGTRRRDDALM
TH_0688|M.thermoresistible__bu GAILRATADLLVEIGYSNLTMSAVAERAGTTKTALYRRWSSKPELVYAAT
MUL_2482|M.ulcerans_Agy99 FAILSATMELLVQIGYSNLSLAAVAERAGTTKSALYRRWSSKAELVHEAA
MAV_1309|M.avium_104 RALYEATLAELTEVGYGGLTMEGIAARAHTGKAALYRRWDTKCELVHAAL
MMAR_4284|M.marinum_M RALYSATLAELIAVGYGRLTMEGIAARAQTGKAALYRRWASKHDLVQAAL
Mb1199c|M.bovis_AF2122/97 RALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAV
Rv1167c|M.tuberculosis_H37Rv RALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAV
MSMEG_3129|M.smegmatis_MC2_155 ADCRAAALAEVAVAGLAGLTVEGVARRASAAKTSVYRHWASVDDLLIDAL
Mvan_2727|M.vanbaalenii_PYR-1 AAIRAAVLELLAEHGPDGVTMDAVAVTAQTSKPVLYRRWPDRRALLRDTL
Mflv_3021|M.gilvum_PYR-GCK AQLLTITLQQLQQHGYDRLTVEAVATQAKASKATLYRRWPSKSDLVLAAF
MAB_2022|M.abscessus_ATCC_1997 SAIRDATYAELQDHGYAGVTFEGVARRAKTSKPVLYRRYRSRAHMVADAL
. : * ::. .:* * : *. :**:: :: :
TH_0688|M.thermoresistible__bu -APTDPVDTVESSDDVAGIVRALIERNRQITATPAARAAMPGLLVDMAAD
MUL_2482|M.ulcerans_Agy99 -FPVTPSALSAPAGDFAGDIRMMVAATRDVFTTPVVRAALPGLVADMTAE
MAV_1309|M.avium_104 VFALPPVPELRSGRSARENLLAMFTAQRDLLAGKTAFPGIE-VIQQLLHE
MMAR_4284|M.marinum_M QYAVPPPPEPRPGRSARENLLTVFTAHRDVLAGKTEFPGLV-AIGQLIHE
Mb1199c|M.bovis_AF2122/97 QYALPPVPEPRADRSARENLLAVFTANCEILAGKTALPSME-IVSQLLHE
Rv1167c|M.tuberculosis_H37Rv QYALPPVPEPRADRSARENLLAVFTANCEILAGKTALPSME-IVSQLLHE
MSMEG_3129|M.smegmatis_MC2_155 AAACPREEVTVEGGHLRDDLLRSLHQLTGWLSGPAAPAVAAVLAERRRRP
Mvan_2727|M.vanbaalenii_PYR-1 LGIATSAFPTVDTGGFRGDMLAVLRAWAALFTGDSAALMRS-AIGAVTAD
Mflv_3021|M.gilvum_PYR-GCK VEGTRLAAVPPRTGSLRDDLLRVGASVCQQACEHAS--TMRAVLNEMSHN
MAB_2022|M.abscessus_ATCC_1997 PTLRYPPTRLASATSLREDVLALLG---ALLRELHRIGVGNYRCLLAEAD
:
TH_0688|M.thermoresistible__bu PRLHRGLLG-RVGSLVEALRRRLAEAAGRGEVQSGVDADRLTELIGGSVM
MUL_2482|M.ulcerans_Agy99 ADLNARVLS-RFTELFATVRIRLQEAVDRGEAHPDVDPNRMIELIGGATM
MAV_1309|M.avium_104 PEMRAIFADAVVRPRLKIVESILQSAVQDGDLDPKS-ITPLTARIGSALI
MMAR_4284|M.marinum_M PELRAIFANSVVHPRLKIIDSVLRAAIREGDLDPDT-VTPFTARIGPALM
Mb1199c|M.bovis_AF2122/97 PELRAIFINSVWAPRLRIVESILQAGVRSGEIDPAT-LTPMTARIGPALI
Rv1167c|M.tuberculosis_H37Rv PELRAIFINSVWAPRLRIVESILQAGVRSGEIDPAT-LTPMTARIGPALI
MSMEG_3129|M.smegmatis_MC2_155 DLVDALYRDVFGTHGNRFTQTVIEHYAATGEIAPRS-VTPVVCDIGEALV
Mvan_2727|M.vanbaalenii_PYR-1 PELAATFRTDVIGARKQEMDAIITRGVQRGEVRADV-PVDLVRELGQSVL
Mflv_3021|M.gilvum_PYR-GCK PDLRKAMQDEFVHQHKLVIDEVLAEAVQRGEIDATAISDEIYDLLPGYLV
MAB_2022|M.abscessus_ATCC_1997 DGLADDMTTAIAGWVDQTVLRALADARERGEIGPEDIPLPVATSI-LALM
: : *: . . : :
TH_0688|M.thermoresistible__bu FRMVLHPDEPITERWADEVAAILIRGVTKEG--------
MUL_2482|M.ulcerans_Agy99 LRVLLYPDQMLDEAWVDQTTAILVHGVTR----------
MAV_1309|M.avium_104 NQHFLLNGSPPNRRELALIVDTVIPPRGSDRAAD-----
MMAR_4284|M.marinum_M NQHFILTGTPPNRRELALIVDTVIPPKRTSTCDNCDN--
Mb1199c|M.bovis_AF2122/97 HQHVLFTGSPPDREQLTRIIDAMILTTGERRES------
Rv1167c|M.tuberculosis_H37Rv HQHVLFTGSPPDREQLTRIIDAMILTTGERRES------
MSMEG_3129|M.smegmatis_MC2_155 IKHQIDTGELPDGSALEAIVDQAILPALGFPATSSGHA-
Mvan_2727|M.vanbaalenii_PYR-1 WHRLLISGDPIDDEVVTRLVDEVLIPVTRPYYEV-----
Mflv_3021|M.gilvum_PYR-GCK FRALVS-ARPPTLKSVRTLVDKVLLPSLGHRGLSKPDGQ
MAB_2022|M.abscessus_ATCC_1997 RHELFFTRKPFGESKLAELFDTVYLPLINLTSRGG----
: .