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MAQLSEPMLTPYRSRRRGEVLERALYSATLAELIAVGYGRLTMEGIAARAQTGKAALYRRWASKHDLVQA ALQYAVPPPPEPRPGRSARENLLTVFTAHRDVLAGKTEFPGLVAIGQLIHEPELRAIFANSVVHPRLKII DSVLRAAIREGDLDPDTVTPFTARIGPALMNQHFILTGTPPNRRELALIVDTVIPPKRTSTCDNCDN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4284 | - | - | 100% (207) | transcriptional regulatory protein |
| M. marinum M | MMAR_1394 | - | 3e-11 | 30.87% (149) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1695 | - | 7e-11 | 27.32% (183) | regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1199c | - | 2e-68 | 67.39% (184) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3021 | - | 2e-20 | 31.44% (194) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1167c | - | 2e-68 | 67.39% (184) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0989 | - | 8e-15 | 33.33% (180) | putative HTH-type transcriptional regulator TetR |
| M. avium 104 | MAV_1309 | - | 1e-76 | 71.57% (197) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3129 | - | 1e-16 | 32.62% (187) | putative HTH-type transcriptional regulator |
| M. thermoresistible (build 8) | TH_4110 | - | 2e-09 | 28.04% (189) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_2482 | - | 1e-11 | 32.03% (153) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2727 | - | 4e-16 | 28.42% (183) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4284|M.marinum_M ----------------------------MAQLSEPMLTPYRSR--RRGEV
MAV_1309|M.avium_104 MQRTLPAAVVRLLRREAADRNAHGYYQEMPQLTD--RTGSRSR--RRGEV
Mb1199c|M.bovis_AF2122/97 ----------------------------MTVSAPAKANPYR----RRGEV
Rv1167c|M.tuberculosis_H37Rv ----------------------------MTVSAPAKANPYR----RRGEV
Mflv_3021|M.gilvum_PYR-GCK ----------------------------MCVVSDPRSDPPSAPLKSRRTA
MAB_0989|M.abscessus_ATCC_1997 ---------------------------MASDVSTGLTKAARGRQVSQWTP
MSMEG_3129|M.smegmatis_MC2_155 -------------------------------------------MRRTGDQ
Mvan_2727|M.vanbaalenii_PYR-1 ------------------------------------------MGRRRGAE
TH_4110|M.thermoresistible__bu ----------------------------VTATDAAATGRAAARGRPRDPA
MUL_2482|M.ulcerans_Agy99 -----------------------------MKADPSSLDKAPGAGRPRDPR
MMAR_4284|M.marinum_M LERALYSATLAELIAVGYGRLTMEGIAARAQTGKAALYRRWASKHDLVQA
MAV_1309|M.avium_104 LERALYEATLAELTEVGYGGLTMEGIAARAHTGKAALYRRWDTKCELVHA
Mb1199c|M.bovis_AF2122/97 LERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLA
Rv1167c|M.tuberculosis_H37Rv LERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLA
Mflv_3021|M.gilvum_PYR-GCK REAQLLTITLQQLQQHGYDRLTVEAVATQAKASKATLYRRWPSKSDLVLA
MAB_0989|M.abscessus_ATCC_1997 REVELLKVTLRLLQEHGYDRLSVDEVAAESKASKATIYRRWPSKAELVLA
MSMEG_3129|M.smegmatis_MC2_155 LKADCRAAALAEVAVAGLAGLTVEGVARRASAAKTSVYRHWASVDDLLID
Mvan_2727|M.vanbaalenii_PYR-1 LDAAIRAAVLELLAEHGPDGVTMDAVAVTAQTSKPVLYRRWPDRRALLRD
TH_4110|M.thermoresistible__bu LDSAILDAALEIFVEQGISALSIEQVARRAGVGKPTIYRRWSDKEQLVAD
MUL_2482|M.ulcerans_Agy99 IDFAILSATMELLVQIGYSNLSLAAVAERAGTTKSALYRRWSSKAELVHE
. .: . * ::: :* : . *. :**:* *:
MMAR_4284|M.marinum_M ALQYAVPPPP--EPRPGRSARENLLTVFTAHRDVLAGKTEFPGLVAIGQL
MAV_1309|M.avium_104 ALVFALPPVP--ELRSGRSARENLLAMFTAQRDLLAGKTAFPGIEVIQQL
Mb1199c|M.bovis_AF2122/97 AVQYALPPVP--EPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQL
Rv1167c|M.tuberculosis_H37Rv AVQYALPPVP--EPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQL
Mflv_3021|M.gilvum_PYR-GCK AFVEGTRLAA--VPPRTGSLRDDLLRVGASVCQQAC-EHASTMRAVLNEM
MAB_0989|M.abscessus_ATCC_1997 AFIEGMRAQL--VRPNTGSLREDLLRIGTNALADVR-RNTPVMRGLLIEI
MSMEG_3129|M.smegmatis_MC2_155 ALAAACPREE--VTVEGGHLRDDLLRSLHQLTGWLSGPAAPAVAAVLAER
Mvan_2727|M.vanbaalenii_PYR-1 TLLGIATSAF--PTVDTGGFRGDMLAVLRAWAALFTGDSAALMRSAIGAV
TH_4110|M.thermoresistible__bu AIEHRVSAELAWPTPAEASVSDPYELVRRNISAAARTAADPAFRGLIAAI
MUL_2482|M.ulcerans_Agy99 AAFPVTPSAL--SAPAGDFAGDIRMMVAATRDVFTTPVVRAALPGLVADM
: :
MMAR_4284|M.marinum_M I----HEPELRAIFANSVVHPR-LKIIDSVLRAAIREGDLDPDTVTPFTA
MAV_1309|M.avium_104 L----HEPEMRAIFADAVVRPR-LKIVESILQSAVQDGDLDPKSITPLTA
Mb1199c|M.bovis_AF2122/97 L----HEPELRAIFINSVWAPR-LRIVESILQAGVRSGEIDPATLTPMTA
Rv1167c|M.tuberculosis_H37Rv L----HEPELRAIFINSVWAPR-LRIVESILQAGVRSGEIDPATLTPMTA
Mflv_3021|M.gilvum_PYR-GCK S----HNPDLRKAMQDEFVHQH-KLVIDEVLAEAVQRGEIDATAISDEIY
MAB_0989|M.abscessus_ATCC_1997 E----RNPALTKAFRTKFVDER-KALIDDVLFAAVQRGEIDADAVNEELW
MSMEG_3129|M.smegmatis_MC2_155 R----RRPDLVDALYRDVFGTHGNRFTQTVIEHYAATGEIAPRSVTPVVC
Mvan_2727|M.vanbaalenii_PYR-1 T----ADPELAATFRTDVIGAR-KQEMDAIITRGVQRGEVRADVPVDLVR
TH_4110|M.thermoresistible__bu YGSAVTHPALLRTYWEHYILPR-RTAAIALLRRARDLGTVAADADLDVLV
MUL_2482|M.ulcerans_Agy99 T----AEADLNARVLSRFTELF--ATVRIRLQEAVDRGEAHPDVDPNRMI
. : : * .
MMAR_4284|M.marinum_M RIGPALMNQHFILTGTPPNRRELALIVDTVIPPKRTSTCDNCDN--
MAV_1309|M.avium_104 RIGSALINQHFLLNGSPPNRRELALIVDTVIPPRGSDRAAD-----
Mb1199c|M.bovis_AF2122/97 RIGPALIHQHVLFTGSPPDREQLTRIIDAMILTTGERRES------
Rv1167c|M.tuberculosis_H37Rv RIGPALIHQHVLFTGSPPDREQLTRIIDAMILTTGERRES------
Mflv_3021|M.gilvum_PYR-GCK DLLPGYLVFRALVSARPPTLKSVRTLVDKVLLPSLGHRGLSKPDGQ
MAB_0989|M.abscessus_ATCC_1997 DLLPGYLVFRSLLPVRSPTADTVRTLVDDVIMPSLTRER-------
MSMEG_3129|M.smegmatis_MC2_155 DIGEALVIKHQIDTGELPDGSALEAIVDQAILPALGFPATSSGHA-
Mvan_2727|M.vanbaalenii_PYR-1 ELGQSVLWHRLLISGDPIDDEVVTRLVDEVLIPVTRPYYEV-----
TH_4110|M.thermoresistible__bu DMLAGAVTYRVLQP-EPPSARQLRCYLEVAYRQVGLLP--------
MUL_2482|M.ulcerans_Agy99 ELIGGATMLRVLLYPDQMLDEAWVDQTTAILVHGVTR---------
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